***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: The present study investigated whether football has favorable effects in the treatment of mild-to-moderate arterial hypertension in untrained middle-aged men . Twenty-five untrained males aged 31 - 54 year with mild-to-moderate hypertension were r and omized to a football training group ( FTG , two 1-h sessions per week ) and a control group receiving physician-guided traditional recommendations on cardiovascular risk factor modification ( doctoral advice group , DAG ) . After 3 months , systolic blood pressure ( SBP ) and diastolic blood pressure ( DBP ) were lowered ( P<0.05 ) by 12 + /- 3 and 7 + /- 1 mmHg in FTG , respectively , whereas no significant changes were observed for DAG , with the 3 months values being lower ( P<0.05 ) in FTG than DAG ( SBP : 138 + /- 2 vs 148 + /- 2 mmHg ; DBP : 84 + /- 2 vs 92 + /- 2 mmHg ) . The resting heart rate was lowered ( P<0.05 ) by 12 + /- 2 b.p.m . in FTG after 3 months ( 67 + /- 3 vs 79 + /- 3 b.p.m . ) , whereas no change was observed for DAG . After 3 months , FTG had higher ( P<0.05 ) VO(2max ) ( 8 + /- 2 % ; 35.0 + /- 1.6 vs 32.5 + /- 1.3 mL/min/kg ) and lower ( P<0.05 ) fat mass ( 1.7 + /- 0.6 kg ) , whereas no change was observed for DAG . In conclusion , football training is an attractive non-pharmacological supplement to the treatment of mild-to-moderate arterial hypertension in untrained middle-aged men The effects of 16 weeks of football or strength training on performance and functional ability were investigated in 26 ( 68.2 ± 3.2 years ) untrained men r and omized into a  football ( FG ; n = 9 ) , a strength training ( ST ; n = 9 ) , or a control group ( CO ; n = 8) . FG and ST trained 1.6 ± 0.1 and 1.5 ± 0.1 times per week , respectively , with higher ( P < 0.05 ) average heart rate ( HR ) ( ∼140 vs 100 bpm ) and time > 90%HRmax ( 17 vs 0 % ) in FG than ST , and lower ( P < 0.05 ) peak blood lactate in FG than ST ( 7.2 ± 0.9 vs 10.5 ± 0.6 mmol/L ) . After the intervention period ( IP ) , VO₂ max ( 15 % ; P < 0.001 ) , cycle time to exhaustion ( 7 % ; P < 0.05 ) , and Yo-Yo Intermittent Endurance Level 1 performance ( 43 % ; P < 0.01 ) were improved in FG , but unchanged in ST and CO . HR during walking was 12 % and 10 % lower ( P < 0.05 ) in FG and ST , respectively , after IP . After IP , HR and blood lactate during jogging were 7 % ( P < 0.05 ) and 30 % lower ( P < 0.001 ) in FG , but unchanged in ST and CO . Sit-to-st and performance was improved ( P < 0.01 ) by 29 % in FG and 26 % in ST , but not in CO . In conclusion , football and strength training for old men  improves functional ability and physiological response to submaximal exercise , while football additionally elevates maximal aerobic fitness and exhaustive exercise performance The study tested the hypothesis that long-term soccer training has positive impact on cardiovascular profile , body composition , bone health , and physical capacity in inactive , pre-menopausal women with mild hypertension . The study applied a r and omized controlled design in which physically inactive middle-aged women were separated into a soccer training group  ( n=19 ; SOC ) and a control group ( n=12 ; CON ) . SOC performed 128±29 ( ±SD ) one-h small-sided soccer training sessions over one year . Blood pressure , body composition , blood lipid profile , and fitness level were determined pre- and post-intervention . Over one year , mean arterial pressure decreased more in SOC than in CON ( -5±7 vs + 4±5 mmHg ; P<.05 ) . Total-body fat mass decreased more ( P<.05 ) in SOC than in CON ( -2.5±2.5 vs + 0.6±3.2 kg ; P<.05 ) , while the change scores for lean body mass were not significantly different in SOC ( 2.6±2.7 kg ) compared to CON ( 1.1±1.9 kg , P=.09 ) . Over one year , change scores in whole-body bone mineral density ( 0.004±0.032 vs -0.019±0.026 g·cm2 ) as well as bone mineral content ( 30±70 vs -39±113 g ) were positive in SOC compared to CON ( P<.05 ) . Post-intervention plasma triglycerides decreased more ( -0.1±0.7 vs + 0.2±0.2 mmol·L-1 ) and HDL cholesterol increased more ( 0.2±0.7 vs -0.2±0.2 mmol·L-1 ) in SOC than in CON ( P<.05 ) . Yo-Yo intermittent endurance level 1 ( 122±105 vs 2±21 % ) and 20-m sprint performance ( 6±6 vs -1±2 % ) increased more ( P<.05 ) in SOC than in CON . In conclusion , long-term soccer training result ed in broad-spectrum improvements in the health profile of untrained , pre-menopausal women with mild hypertension , including cardiovascular , metabolic , and musculo-skeletal benefits The purpose of this study was to determine the effects of recreational soccer ( SOC ) compared to moderate-intensity continuous running ( RUN ) on all health-related physical fitness components in healthy untrained men . Sixty-nine participants were recruited and r and omly assigned to one of three groups , of which sixty-four completed the study : a soccer training group ( SOC ; n = 20 , 34±4 ( means±SD ) years , 78.1±8.3 kg , 179±4 cm ) ; a running group ( RUN ; n = 21 , 32±4 years , 78.0±5.5 kg , 179±7 cm ) ; or a passive control group ( CON ; n = 23 , 30±3 years , 76.6±12.0 kg , 178±8 cm ) . The training intervention lasted 12 weeks and consisted of three 60-min sessions per week . All participants were tested for each of the following physical fitness components : maximal aerobic power , minute ventilation , maximal heart rate , squat jump ( SJ ) , countermovement jump with arm swing ( CMJ ) , sit- and -reach flexibility , and body composition . Over the 12 weeks , VO2max relative to body weight increased more ( p<0.05 ) in SOC ( 24.2 % , ES = 1.20 ) and RUN ( 21.5 % , ES = 1.17 ) than in CON ( -5.0 % , ES = -0.24 ) , partly due to large changes in body mass ( -5.9 , -5.7 and + 2.6 kg , p<0.05 for SOC , RUN and CON , respectively ) . Over the 12 weeks , SJ and CMJ performance increased more ( p<0.05 ) in SOC ( 14.8 and 12.1 % , ES = 1.08 and 0.81 ) than in RUN ( 3.3 and 3.0 % , ES = 0.23 and 0.19 ) and CON ( 0.3 and 0.2 % ) , while flexibility also increased more ( p<0.05 ) in SOC ( 94 % , ES = 0.97 ) than in RUN and CON ( 0–2 % ) . In conclusion , untrained men displayed marked improvements in maximal aerobic power after 12 weeks of soccer training and moderate-intensity running , partly due to large decreases in body mass . Additionally soccer training induced pronounced positive effects on jump performance and flexibility , making soccer an effective broad-spectrum fitness training intervention Summary And rogen deprivation therapy ( ADT ) for prostate cancer ( PCa ) impairs musculoskeletal health . We evaluated the efficacy of 32-week football training on bone mineral density ( BMD ) and physical functioning in men undergoing ADT for PCa . Football training improved the femoral shaft and total hip BMD and physical functioning parameters compared to control . Introduction ADT is a mainstay in PCa management . Side effects include decreased bone and muscle strength and increased fracture rates . The purpose of the present study was to evaluate the effects of 32 weeks of football training on BMD , bone turnover markers ( BTMs ) , body composition , and physical functioning in men with PCa undergoing ADT . Methods Men receiving ADT > 6 months ( n = 57 ) were r and omly allocated to a football training group ( FTG ) ( n = 29 ) practising 2–3 times per week for 45–60 min or to a st and ard care control group ( CON ) ( n = 28 ) for 32 weeks . Outcomes were total hip , femoral shaft , femoral neck and lumbar spine ( L2-L4 ) BMD and systemic BTMs ( procollagen type 1 amino-terminal propeptide , osteocalcin , C-terminal telopeptide of type 1 collagen ) . Additionally , physical functioning ( postural balance , jump height , repeated chair rise , stair climbing ) was evaluated . Results Thirty-two-week follow-up measures were obtained for FTG ( n = 21 ) and for CON ( n = 20 ) , respectively . Analysis of mean changes from baseline to 32 weeks showed significant differences between FTG and CON in right ( 0.015 g/cm2 ) and left ( 0.017 g/cm2 ) total hip and in right ( 0.018 g/cm2 ) and left ( 0.024 g/cm2 ) femoral shaft BMD , jump height ( 1.7 cm ) and stair climbing ( −0.21 s ) all in favour of FTG ( p < 0.05 ) . No other significant between-group differences were observed . Conclusions Compared to st and ard care , 32 weeks of football training improved BMD at clinical ly important femoral sites and parameters of physical functioning in men undergoing ADT for PCa The study examined the effects of 1 year of football or strength training on cardiovascular function in 65- to 75-year-old men . Twenty-six untrained men ( age : 68.2 ± 3.2 years ) were r and omized to football training ( FTG ; n = 9 ) , strength training ( STG ; n = 9 ) , or control ( CG ; n = 8) . In FTG , left ventricular ( LV ) internal diastolic diameter , end-diastolic volume , and mass index were 8 % , 21 % , and 18 % higher ( P < 0.01 ) , respectively , after 12 months , with no changes in STG and CG . After 12 months , LV ejection fraction was increased ( P < 0.05 ) by 8 % and 5 % in FTG and STG , respectively , and systolic longitudinal two-dimensional strain by 8 % and 6 % , whereas right ventricular systolic function improved ( P < 0.05 ) by 22 % in FTG , but not in STG and CG . In FTG , LV diastolic mitral inflow ( E/A ) ratio and peak early diastolic velocity ( E ' ) improved ( P < 0.05 ) by 25 % and 12 % , respectively , after 12 months , with no changes in STG and CG . In FTG , maximum oxygen uptake was 16 % and 18 % higher ( P < 0.001 ) after 4 and 12 months , respectively , and resting heart rate was 6 and 8 beats per minute lower ( P < 0.001 ) , respectively , with no changes in STG and CG . In conclusion , football training elicited superior cardiovascular effects  compared with strength training in elderly untrained men Abstract We investigated the musculoskeletal health profile of  elite female football players ( ET ) in comparison to untrained ( UT ) young women subjected to 16 weeks of football training ( 2 × 1 h per week ) .  DXA scans , blood sampling , sprint testing and Flamingo postural balance testing were carried out for 27 Danish national team players and 28 untrained women , with eight women being tested after training .  At baseline total BMD and BMC were 13 % ( 1.305 ± 0.050 versus 1.159 ± 0.056 g · cm−2 ) and 23 % ( 3047 ± 235 versus 2477 ± 526 g ) higher ( P < 0.001 ) and leg BMD and BMC were 24 and 28 % higher ( P < 0.01 ) in ET than in UT . Resting plasma osteocalcin was 45 % higher in ET than in UT ( 28.8 ± 10.9 versus  
    Output:
    
Irrespective of age or sex , these health benefits were observed in both , untrained individuals and clinical population s. In conclusion , findings from this systematic review suggest that acute SSSG  may elicit high cardiovascular and metabolic dem and s in untrained healthy adults and clinical population s. Moreover , this type of exercise is safe with positive long-term effects on physical fitness and health indices .