***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: OBJECTIVE This prospect i ve study assessed treatment outcome and patient satisfaction of oral cancer patients with a m and ibular overdenture on implants up to 5 years after treatment . MATERIAL S AND METHODS At baseline , 50 consecutive edentulous oral cancer patients , in whom prosthetic problems were expected after oncological treatment , were evaluated by st and ardized question naires and clinical assessment s. All implants were installed during ablative tumour surgery in native bone in the interforaminal area . About two-thirds of the patients ( n=31 ) had radiotherapy post-surgery  ( dose > 40 Gy in the interforaminal area ) . RESULTS At the 5-year evaluation , 26 patients had passed away and four patients had to be excluded from the analyses , because superstructures were not present , due to persistent local irritation ( n=2 ) , loss of three implants ( n=1 ) and the impossibility of making an overdenture related to tumour and oncological surgery-driven anatomical limitations ( n=1 ) . In the remaining 20 patients , the prosthesis was still in function ( 76 implants ) . During the 5-year follow-up , total 14 implants were lost , 13 in irradiated bone ( survival rate 89.4 % , dose > 40 Gy ) and one in non-irradiated bone ( survival rate 98.6 % ) . Peri-implant tissues had a healthy appearance and remained healthy over time . Patients were satisfied with their dentures . CONCLUSIONS It was concluded that oral cancer patients can benefit from implants installed during ablative surgery , with a high survival rate of the implants , a high percentage of rehabilitated patients and a high denture satisfaction up to 5 years after treatment In this prospect i ve study , we determined the effects of the time interval between irradiation and implant therapy , implant location , bone-resection surgery , and irradiation dose on implant survival . We analyzed the survival of 446 implants inserted after radiotherapy over a period of up to 14 years in 130 consecutive patients treated for oral cancer . The 10-year overall Kaplan-Meier implant survival percentage is 78 % . The difference in survival percentages of implants inserted < 1 year and ≥ 1 year after irradiation ( 76 % and 81 % , respectively ) is not significant . We concluded that implant survival is significantly influenced by the location ( maxilla or m and ible , 59 % and 85 % , respectively ; p = 0.001 ) , by the incidence of bone-resection surgery in the jaw where the implant was installed ( p = 0.04 ) , and by the irradiation dose at the implant site ( < 50 Gray or ≥ 50 Gray , p = 0.05 ) Surgical treatment of malignancies in the oral cavity and subsequent radiotherapy often result in an anatomic and physiological oral condition unfavorable for prosthodontic rehabilitation . The objective of this prospect i ve study was to assess the effect of hyperbaric oxygen therapy on treatment outcome ( condition of peri-implant tissues , implant survival , oral functioning and quality of life ) of prosthodontic rehabilitation with implant-retained lower dentures in radiated head and neck cancer patients 6 weeks and 1 year after placing the new dentures . The treatment outcome was assessed in a group of 26 head neck cancer patients who were subjected to radiotherapy after tumour surgery .  St and ardized question naires were completed and clinical and radiographic assessment s were performed . After r and omization , endosseous Brånemark implants were placed in the anterior part of the m and ible either under antibiotic prophylaxis ( 13 patients ) or under antibiotic prophylaxis combined with pre and postsurgery hyperbaric oxygen ( HBO ) treatment ( 13 patients ) . In the HBO and non-HBO group eight implants ( implant survival 85.2 % ) and three implants ( implant survival 93.9 % ) were lost , respectively . Peri-implant tissues had a healthy appearance in both groups . Osteoradionecrosis developed in one patient in the HBO group . All patients functioned well with their implant-retained lower denture . The quality of life related to oral functioning and denture satisfaction were improved to a comparable extent in the HBO and non-HBO group . Implant-retained lower dentures can improve the quality of life related to oral functioning and denture satisfaction in head and neck cancer patients . Adjuvant hyperbaric oxygen therapy could not be shown to enhance implant survival in radiated m and ibular jaw bone In this multicenter study , submerged implants were prospect ively followed to evaluate their long-term prognosis in irradiated patients . In a total of 77 patients treated for oral or neck cancer , 188 implants were consecutively placed . After a healing period , the successfully integrated implants were restored with 69 removable and 38 fixed restorations . The implants cumulative survival and success rates were evaluated over a period of at least 36 months . In addition , cumulative success rates were calculated for implant subgroups divided per implant site ( m and ible or maxilla ) , radiation dosage , and the time interval between the last irradiation and implant placement . During the healing period , 20 implants did not successfully integrate , whereas 168 implants were classified as success ( including both survival and success rates ) . The analysis of implant subgroups showed slightly more favorable cumulative success rate for m and ibular implants ( 98.4 % ) compared with maxillary implants ( 57.1 % ) and clearly better success rate for a radiation dosage minor of 50-Gy doses . A time greater than 12 months as interval between last irradiation and implant placement seems not to promote better clinical results The aim of this prospect i ve study was to assess treatment outcome and impact on quality of life of prosthodontic rehabilitation with implant-retained prostheses in head-neck cancer patients . Fifty patients were evaluated by st and ardized question naires and clinical assessment . All received the implants during ablative tumour surgery in native bone in the interforaminal area . About two-thirds of the patients ( n=31 ) needed radiotherapy post-surgery . Both in irradiated and non-irradiated bone two implants were lost 18 - 24 months after installation . Peri-implant tissues had a healthy appearance . No cases of osteoradionecrosis occurred . In 15 patients no functional implant-retained lower dentures could be made for various reasons . The other 35 patients all functioned well , with an improvement in quality of life . Major improvement was observed in the non-irradiated patients . In the irradiated patients , less improvement in many functional items was observed , while items related to the oral sequelae of radiotherapy did not improve . Similar to the quality -of-life assessment s , denture satisfaction was improved and tended to be higher in non-irradiated than irradiated patients . Implant-retained lower dentures can substantially improve the quality of life related to oral functioning and denture satisfaction in head-neck cancer patients . This effect is greater in non-irradiated than irradiated cancer patients 
    Output:
    
Dental implants installed in the irradiated area of an oral cavity have a high survival rate , but strict monitoring is needed to prevent complications , thereby reducing possible failures