***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: BACKGROUND The aim of the present prospect i ve longitudinal study of periodontally diseased and periodontally healthy patients was a clinical , microbiological , and radiographic comparison of teeth and implants and an assessment of the implant success rate . METHODS Thirty-nine partially edentulous patients provided with a total of 150 implants were enrolled in the study . Oral rehabilitation was undertaken in 15 patients treated for generalized aggressive periodontitis ( GAgP ) , 12 patients treated for generalized chronic periodontitis ( GCP ) , and 12 periodontally healthy patients . The examinations of the teeth and implants were carried out within the framework of a 3-month recall schedule over a 3-year period . At each session , clinical parameters for probing depth ( PD ) , gingival recession ( GR ) , attachment level ( AL ) , gingival index ( GI ) , and plaque index ( PI ) were recorded , and the composition of the subgingival microflora determined by dark-field microscopy . In the periodontally diseased patients , Actinobacillus actinomycetemcomitans ( A.a . ) , Porphyromonas gingivalis ( P.g . ) , and Prevotella intermedia ( P.i . ) were detected at teeth and implants by DNA analysis in the first and third years after insertion of the superstructure . Intraoral radiographs of the teeth and implants were taken at baseline , immediately after insertion of the superstructure , and then 1 and 3 years later . RESULTS The GI and PI at implants and teeth remained below 0.25 and 0.6 , respectively , in all patient groups throughout the study period . At the implants and teeth , a slight increase in PD and a continuous attachment loss was recorded in the GAgP patients . The attachment loss was greater at the implants than at the teeth in all groups . The morphological distribution of the microorganisms revealed virtually healthy conditions in all groups . A.a . was detected in two GAgP patients , whereas P.g . and P.i . were found more frequently both in the GAgP and in the GCP patients . Radiographically detected bone loss was higher after 3 years at implants and teeth in the GAgP patients than in the other two groups . The implant success rates recorded were 100 % in the periodontally healthy and GCP patients , and 95.7 % in the maxilla and 100 % in the m and ible of the GAgP patients . CONCLUSIONS The results show that oral rehabilitation can be performed with implants in patients treated for generalized aggressive and chronic periodontitis . However , slight attachment loss and bone loss were registered at the implants and teeth in the patients with aggressive periodontitis OBJECTIVES To evaluate the long-term survival rates of dental implants  according to the patient 's periodontal status , as well as to estimate if the effect of periodontal status regarding implant failure is constant throughout the long-term follow-up . MATERIAL S AND METHODS This was a historical prospect i ve cohort study design of all consecutive patients operated from 1996 to 2006 at a periodontal clinic . The cohort consisted of 736 patients , with a total of 2336 dental implants .  An extended Cox proportional hazards model , which includes interaction terms between survival time and variables of interest , was used . RESULTS Patients ' mean ( SD ) age was 51.13 ( 12.35 ) . The follow-up time was up to 144 months , with a mean ( SD ) of 54.4 ( 35.6 ) months . The overall implant raw survival rate was 95.9 % . The Kaplan-Meier estimates for the cumulative survival rate ( CSR ) at 108 months were 0.96 and 0.95 for implants inserted into healthy and moderate chronic periodontal patients , respectively . The CSR declined to 0.88 at 108 months for the severe periodontitis group . The extended Cox model revealed that severe chronic status turned out to be a significant risk factor for implant failure after 50 months of follow-up [ hazard ratio (HR)=8.06 ; p<0.01 ] . The extended Cox model for smoking indicates a near-significant effect after 50 months ( HR=2.76 ; p=0.061 ) . CONCLUSIONS Periodontal status and smoking are significant risk factors for late implant failures . The HR for periodontal and smoking status are not constant throughout the follow-up period PURPOSE The purpose of this study was to analyze the current literature s and to assess outcomes of  implant treatment in patients with generalized aggressive periodontitis . MATERIAL S AND METHODS Studies considered for inclusion were search ed in Pub-Med . The literature search for studies published in English between 2000 and 2012 was performed . Our findings included literature assessing implant treatment in patients with a history of generalized aggressive periodontitis ( GAP ) . All studies were screened according to inclusion criteria . The outcome measures were survival rate of superstructures , marginal bone loss around implant and survival rate of implants . All studies were divided into two follow-up period : short term study ( < 5 years ) and long term study ( ≥ 5 years ) . RESULTS Seven prospect i ve studies were selected , including four short-term and three long-term studies . The survival rates of the superstructures were generally high in patients with GAP , i.e. 95.9 - 100 % . Marginal bone loss around implant in patients with GAP as compared with implants in patients with chronic periodontitis or periodontally healthy patients was not significantly greater in short term studies but was significantly greater in long term studies . In short term studies , the survival rates of implants were between 97.4 % and 100 % in patients with GAP-associated tooth loss , except one study . The survival rates of  implants were between 83.3 % and 96 % in patients with GAP in long term studies . CONCLUSION Implant treatment in patients with GAP is not contraindicated provided that adequate infection control and an individualized maintenance program are assured BACKGROUND The successful use of osseointegrated implants in periodontally healthy patients has been documented in numerous longitudinal studies in recent years . However , the extent to which these positive results apply to periodontally diseased patients remains unclear . The aim of the present prospect i ve longitudinal study of partially edentulous patients treated for generalized chronic periodontitis and generalized aggressive periodontitis was a clinical , microbiological , and radiographic comparison of teeth and implants and assessment of the implant success rate . METHODS Five partially edentulous patients treated for generalized aggressive periodontitis ( GAgP ) and 5 treated for generalized chronic periodontitis ( GCP ) were enrolled in this study . The GAgP patients received 36 implants , and the GCP patients 12 implants .  The teeth were examined 2 to 4 weeks before extraction of the non-retainable teeth ( baseline ) , and 3 weeks after insertion of the final abutments ( second examination ) . All further examinations were performed during a 3-month recall schedule over a 5-year period for the GAgP patients and over a 3-year period for the GCP patients . At each session clinical parameters were recorded at teeth and implants and the composition of the subgingival microflora was determined by dark-field microscopy and DNA analysis . Intraoral radiographs of the teeth and implants were taken for control purpose s at baseline ; after insertion of the superstructure ; and 1 , 3 , and 5 years later . RESULTS The clinical findings indicated healthy periodontal and peri-implant conditions in both patient groups throughout the study . However , an increased probing depth and an attachment loss were recorded in the GAgP patients after the third year ( P<0.001 ) . The distribution of the microorganisms revealed no significant differences between the patient groups or between implants and teeth . Moderate bone loss at teeth and implants was registered in both groups . The success rates recorded were 100 % in the GCP patients and 88.8 % ( maxilla : 85.7 % ; m and ible : 93.3 % ) in the GAgP patients . CONCLUSIONS The 3-year and 5-year follow-ups show that osseointegrated implants may be successful in oral rehabilitation of partially edentulous patients treated for generalized aggressive periodontitis and generalized chronic periodontitis . However , as no significant differences were recorded between conditions at teeth and at implants , progression of the disease can not be ruled out BACKGROUND The aim of this prospect i ve 10-year study of partially edentulous subjects treated for generalized aggressive periodontitis and periodontally healthy subjects was a clinical , microbiologic , and radiographic comparison of teeth and implants and assessment of the implants ' success rate . METHODS Five subjects treated for generalized aggressive periodontitis ( GAgP ) and five periodontally healthy subjects who were orally rehabilitated with osseointegrated implants  participated in the study . First , they were examined 2 to 4 weeks before extraction of the non-retainable teeth ( baseline ) and 3 weeks after insertion of the final abutments . All further examinations were performed during a 3-month recall schedule over a 10-year period . At every session , clinical parameters were recorded , and the composition of the subgingival microflora was determined . Radiographs were taken at baseline after insertion of the superstructure and 1 , 3 , 5 , 8 , and 10 years later . RESULTS Throughout the follow-up period , the peri-implant gingival index of GAgP subjects was significantly higher than in periodontally healthy subjects . There was no difference in plaque index between teeth and implants or between the two groups . The peri-implant probing depths were comparable in the two groups and remained < or = 4 mm throughout the follow-up . The probing depth was significantly higher around the teeth of the GAgP subjects compared to periodontally healthy subjects . Implants of GAgP subjects showed a significantly higher attachment loss ( Ø 2.4 mm ) . The attachment level at teeth and implants of the periodontally healthy subjects and at teeth of the GAgP subjects was almost unchanged . Microbiologically , GAgP subjects had fewer cocci and more motile rods and filaments at teeth and implants than periodontally healthy subjects . GAgP subjects showed significantly more peri-implant bone loss in the first year ( Ø 2.07 mm ) and in the subsequent 9 years ( total 1.3 mm ) . Bone loss at teeth also was significantly higher at baseline ( Ø 26.39 % ) and in the following years ( total 9.3 % ) . Implant survival rates were 100 % in periodontally healthy subjects versus 83.33 % in GAgP subjects . CONCLUSIONS This 10-year study showed that partially edentulous subjects treated for GAgP can be rehabilitated successfully with osseointegrated implants . However , the bone and attachment loss at the implants were higher than in periodontally healthy subjects This study evaluated the efficacy of implant supported dental restorations in patients with chronic periodontal diseases at various stages within 2 years of completing treatment . 30 patients with periodontal diseases and 30 patients without periodontal diseases were studied . Total counts of 276 implant bodies were divided into group A ( patients with periodontal diseases ; a total of 149 implants ) and group B ( patients with healthy periodontium ; a total of 127 implants ) . In group A subjects , periodontitis was treated prior to implant placement . The study focused on patients ' modified sulcus bleeding index , modified plaque index , implant mobility index , periodontal probing depth and implant success rate 12 and 24 months after the completion of the treatment . The result show : there were no significant differences in implant success rate between groups A and B ; modified sulcus bleeding index scores showed differences between the groups 24 months after treatment ; there were no significant differences in other clinical indexes during the study between the groups ; there were no significant differences in periodontal probing depth between the groups ; modified plaque index and modified sulcus bleeding index were positively correlated in implant supported dental restoration patients with chronic periodontal diseases 
    Output:
    
Strong evidence suggests that periodontitis is a risk factor for implant loss ; moderate evidence revealed that periodontitis is a risk factor for peri-implantitis and that patients with periodontitis have higher implant-bone loss