***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: OBJECTIVES /HYPOTHESIS Nasal disease , including chronic rhinosinusitis and allergic rhinitis , is a significant source of morbidity . Nasal irrigation has been used as an adjunctive treatment of sinonasal disease . However , despite an abundance of anecdotal reports , there has been little statistical evidence to support its efficacy . The objective of this study was to determine the efficacy of the use of pulsatile hypertonic saline nasal irrigation in the treatment of sinonasal disease . STUDY DESIGN A prospect i ve controlled clinical study . METHODS Two hundred eleven patients from the University of California , San Diego ( San Diego , CA ) Nasal Dysfunction Clinic with sinonasal disease ( including allergic rhinitis , aging rhinitis , atrophic rhinitis , and postnasal drip ) and 20 disease-free control subjects were enrolled . Patients irrigated their nasal cavities using hypertonic saline delivered by a Water Pik device using a commercially available nasal adapter twice daily for 3 to 6 weeks . Patients rated nasal disease-specific symptoms and completed a self-administered quality of well-being question naire before intervention and at follow-up . RESULTS Patients who used nasal irrigation for the treatment of sinonasal disease experienced statistically significant improvements in 23 of the 30 nasal symptoms queried . Improvement was also measured in the global assessment of health status using the Quality of Well-Being scale . CONCLUSIONS Nasal irrigation is effective in improving symptoms and the health status of patients with sinonasal disease OBJECTIVE Evaluation of the endoscopic transseptal approach of vidian neurectomy . DESIGN A case series , with a follow-up of 12 to 24 months . SETTING A referral center . PATIENTS A consecutive sample of 11 adult patients with resistant vasomotor rhinitis : eight with severe rhinorrhea and three with recurrent nasal polyposis . All patients had a negative history of allergy and negative skin tests . All patients completed the study . INTERVENTION The rigid nasal endoscope was used through a transseptal approach to reach the sphenopalatine foramen and to cut the vidian nerve . MAIN OUTCOME MEASURES Intraoperative identification and cutting of the vidian nerve under direct endoscopic vision . Postoperative evaluation of rhinorrhea , sneezing , and recurrent disease . RESULTS The vidian nerve was identified and sectioned bilaterally in all cases . Immediate and complete cessation of rhinorrhea uniformly occurred . Paroxysms of sneezing were vastly reduced . No recurrence was detected , except in one case . Three patients complained of dry eyes , but they had symptomatic relief with artificial teardrops . CONCLUSION The technique of endoscopic transseptal vidian neurectomy is a minor surgical procedure with high efficacy and minimal postoperative morbidity . More cases and longer follow-up are necessary to provide long-term results 
    Output:
    
The text of two recent otolaryngology text books was also review ed , and the main results of the study revealed the prevalence of NAR had not previously been studied in Oman .
The study found that more than half of rhinitis patients suffered from NAR .
There are no specific diagnostic tests for NAR ; a thorough case history is the best diagnostic tool to date .