***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: Psychological stress among breast cancer patients can inhibit immune function and contribute to disease progression . We investigated the effects of autogenic training ( AT ) , a relaxation method for reducing stress , on salivary immunoglobulin A ( sIgA ) in breast cancer surgery patients . Thirty patients scheduled to undergo breast cancer surgery were r and omly assigned to an AT or control group ( usual care ) . Patients in the AT group underwent training for 7 days after surgery . Salivary IgA and heart rate variability were assessed on the day before surgery , and on the third and seventh postoperative days . Levels of sIgA were significantly higher on the seventh postoperative day in the AT group ( n = 7 ) compared to the control group ( n = 7 ) ( p = 0.049 ) . These findings suggest that AT may improve immune function in breast surgery patients Objective —To compare the efficacy in runners of two relaxation  techniques with regard to exercise reactivity and recovery after exercise . Methods —Thirty one adult male runners were studied prospect ively for six months in three groups practising either meditation ( n = 11 ) or autogenic training ( n = 11 ) or serving as controls ( n = 10 ) . Before and after the six months relaxation intervention , indicators of reactivity to exercise and metabolism after exercise ( blood lactate concentration , heart rate ( HR ) , and oxygen consumption ( Vo2 ) ) , were tested immediately after and 10 minutes after exercise . Resting HR was also assessed weekly at home during the trial . State anxiety was measured before and after the intervention . Results —After the relaxation training , blood lactate concentration after exercise was significantly ( p<0.01 ) decreased in the meditation group compared with the control group . No difference was observed in lactate responses between the autogenic training group and the control group . There were no significant differences among the groups with regard to HR , Vo2 , or levels of anxiety . Conclusion —Meditation training may reduce the lactate response to a st and ardised exercise bout Objectives A recent meta- analysis concluded that multicomponent treatments are effective for some fibromyalgia ( FM ) symptoms . The objective of this study was to examine whether a psychoeducational intervention implemented in primary care is more effective than usual care for improving the functional status of patients with FM . Methods This study was based on a r and omized controlled trial . The 484 patients with FM included in a data base of the Viladecans Hospital ( Barcelona , Spain ) were eligible for screening . Finally , 108 patients were r and omly assigned to the intervention and 108 patients were assigned to usual care . The intervention comprised nine 2-hour sessions ( 5 sessions of education and 4 sessions of autogenic relaxation ) . The patients were assessed before and after the intervention with a battery of instruments ( measuring sociodemographic data , medical comorbidities , functional status , trait anxiety , and social desirability ) . Results The posttreatment drop-out rate was 9.7 % ( intervention : 6.5 % ; control : 13 % ) . The intention-to-treat analyses showed significant differences between the groups at posttreatment : the intervention group improved in physical impairment , days not feeling well , pain , general fatigue , morning fatigue , stiffness , anxiety , and depression ( medium effect size in most cases ) . The patients who responded to the intervention reported less trait anxiety at baseline than nonresponders . The absolute risk reduction with the intervention was 36.1 % ( 95 % confidence interval : 23.3 - 48.8 ) and the number needed to treat was 3 ( 95 % confidence interval : 2.0 - 4.3 ) . Discussion A 2-month psychoeducational intervention improves the functional status of FM patients to a greater extent than usual care , at least in the short-term . The social desirability bias did not explain the reported outcomes . Trait anxiety was associated with response to treatment . Trial Registration NCT00550966 The purpose of this study was to investigate the effects of acute aerobic activity an an autogenic relaxation session on reducing  induced state anxiety . Eighty-five university students were r and omly assigned to one of three groups ( a ) aerobic , ( b ) relaxation , ( c ) control . Each group was tested separately . The general procedure consisted of anxiety induction , assessment , intervention , and assessment . The induced affect procedure involved having subjects visualize distressing images and generating high arousal states for ten minutes ( Smith and Ascough , 1985 ) . State anxiety was assessed by State-Trait Anxiety Inventory ( form Y-1 ) . The aerobic intervention lasted 40 minutes , including warm-up and cool-down . The relaxation intervention consisted of listening and following instructions on a tape for approximately 30 minutes ( Budzyski T , 1974 , " Limb Heaviness-Exercise MU3 - 3 " ) . The control group was excused after anxiety induction and told to report back in 30 minutes . The data was analyzed by a 3 x 2 ( groups by time ) ANOVA with repeated measures on the last factor . The groups by times interaction was significant , F(2,82 ) = 13.07 , p less than 0.01 . Post-hoc analysis using Tukey with a normalized n indicated that both the aerobic and relaxation groups significantly reduce anxiety scores from pretreatment to post-treatment but were not different from each other . Both groups were significantly different from the control . The findings support the argument that an acute aerobic activity and relaxation session can reduce induced anxiety . These results have implication s for motivating individuals to engage in exercise and activity to relieve anxiety generated by an acute stressor An experimental study was conducted among 60 menopausal women , 30 each in experimental and control group who met inclusion criteria . The menopausal women were identified in both the groups and level of depression was assessed using Cornell Dysthmia rating scale . Simple r and om sampling technique by lottery method was used for selecting the sample . Autogenic relaxation was practice d by the menopausal women for four weeks . The findings revealed that in experimental group , after intervention of autogenic relaxation on depression among menopausal women , 23 ( 76.7 % ) had mild depression . There was a statistically significant effectiveness in experimental group at the level of p < 0.05 . There was a statistically significant association between the effectiveness of  autogenic relaxation  on depression among menopausal women in the post-experimental group with the type of family at the level of p < 0.05 It is not established whether behavioral interventions add benefit to pharmacological therapy for hypertension . We hypothesized that behavioral neurocardiac training ( BNT ) with heart rate variability biofeedback would reduce blood pressure further by modifying vagal heart rate modulation during reactivity and recovery from st and ardized cognitive tasks ( “ mental stress ” ) . This r and omized , controlled trial enrolled 65 patients with uncomplicated hypertension to BNT or active control ( autogenic relaxation ) , with six 1-hour sessions over 2 months with home practice .  Outcomes were analyzed with linear mixed models that adjusted for antihypertensive drugs . BNT  reduced daytime and 24-hour systolic blood pressures ( −2.4±0.9 mm Hg , P=0.009 , and −2.1±0.9 mm Hg , P=0.03 , respectively ) and pulse pressures ( −1.7±0.6 mm Hg , P=0.004 , and −1.4±0.6 mm Hg , P=0.02 , respectively ) . No effect was observed for controls ( P>0.10 for all indices ) . BNT also increased RR-high-frequency power ( 0.15 to 0.40 Hz ; P=0.01 ) and RR interval ( P<0.001 ) during cognitive tasks . Among controls , high-frequency power was unchanged ( P=0.29 ) , and RR interval decreased ( P=0.03 ) . Neither intervention altered spontaneous baroreflex sensitivity ( P>0.10 ) . In contrast to relaxation therapy , BNT with heart rate variability biofeedback modestly lowers ambulatory blood pressure during wakefulness , and it augments tonic vagal heart rate modulation . It is unknown whether efficacy of this treatment can be improved with biofeedback of baroreflex gain . BNT , alone or as an adjunct to drug therapy , may represent a promising new intervention for hypertension Objectives : To explore autogenic training ( AT ) as a treatment for psychological morbidity , symptomology , and physiological markers of stress among women with chest pain , a positive exercise test for myocardial ischemia , and normal coronary arteries ( cardiac syndrome X ) . Design : Fifty-three women with cardiac syndrome X ( mean ± SD age , 57.1 ± 8 years ) were r and omized to an 8-week AT program or symptom diary control . Symptom severity and frequency , Hospital Anxiety and Depression Scale , Spielberger State-Trait Anxiety Inventory , Cardiac Anxiety Question naire ( CAQ ) , and Ferrans and Powers Quality of Life Index ( QLI ) , blood pressure , heart rate , electrocardiogram , and plasma catecholamines  were measured before and after intervention and at the 8-week follow-up . Results : Women who underwent AT had improved symptom frequency ( 8.04 ± 10.08 vs 1.66 ± 2.19 , P < 0.001 ) compared with control women and reduced symtom severity ( 2.08 ± 1.03 vs 1.23 ± 1.36 , P = 0.02 ) and frequency ( 6.11 ± 3.17 vs 1.66 ± 2.19 , P < 0.001 ) post-AT compared with baseline within group . Within-group improvements among women who underwent AT include QLI health functioning ( 17.80 ± 5.74 vs 19.41 ± 5.19 , P = 0.04 ) and CAQ fear ( 1.53 ± 0.61 vs 1.35 ± 0.56 , P = 0.02 ) post-AT and QLI health functioning ( 17.80 ± 5.74 vs 20.09 ± 5.47 , P = 0.01 ) , CAQ fear ( 1.53 ± 0.61 vs 1.30 ± 0.67 , P = 0.002 ) , CAQ total ( 1.42 ± 0.54 vs 1.29 ± 0.475 , P = 0.04 ) , Spielberger State-Trait Anxiety Inventory trait anxiety ( 42.95 ± 11.19 vs 38.68 ± 11.47 , P = 0.01 ) , and QLI quality of life ( 20.67 ± 5.37 vs 21.9 ± 4.89 , P = 0.02 ) at follow-up . Conclusion : An 8-week AT program improves symptom frequency , with near-significant improvements in symptom severity in women with cardiac syndrome The aim of the present study was ( a ) to investigate the relative efficacy of autogenic training and future oriented hypnotic imagery in the treatment of  tension headache  and ( b ) to explore the extent to which therapy factors such as relaxation , imagery skills , and hypnotizability mediate therapy outcome . Patients were r and omly assigned to the 2 therapy conditions and therapists . 55 patients ( 28 in the autogenic therapy condition and 27 in the future oriented hypnotic imagery condition ) completed the 4 therapy sessions and 2 assessment sessions . No significant main effect or interaction effects for treatment condition or therapist was revealed . A significant effect for time in analyzing scores for headache pain , pain medication usage , depression , and state anxiety was found . In the self-hypnosis condition , pain reduction proved to be associated with depth of relaxation during home practice ( as assessed with diaries ) and capacity to involve in imagery ( as assessed with the Dutch version [ van der Velden & Spinhoven , 1984 ] of the Creative Imagination Scale [ Barber & Wilson , 1978/79 ; Wilson & Barber , 1978 ] ) . After statistically controlling for relaxation and imagery , hypnotizability scores ( as assessed with the Dutch version [ Oyen & Spinhoven , 1983 ] of the Stanford Hypnotic Clinical Scale [ Morgan & J.R. Hilgard , 1975 , 1978/79 ] ) were significantly correlated with ratings of pain reduction . Results are discussed in the context of the neo-dissociation and social-cognitive model of hypnoanalgesia . The clinical relevance and the method ological shortcomings of the present study are also critically assessed OBJECTIVES Autogenic training ( AT ) is a method of autosuggestion with some potential for reducing anxiety . This study tests whether AT lowers anxiety levels experienced by patients undergoing coronary angioplasty . METHODS Fifty-nine patients were r and omly assigned to receive regular AT or no such therapy as an adjunct to st and ard care for 5 months . The primary outcome measure was State Anxiety at 2 months . Qualitative information was generated by face-to-face interviews . RESULTS State Anxiety showed a significant intergroup difference both at 2 and 5 months . This finding was corroborated by secondary outcome measures , for example , quality of life , and by qualitative information about patients ' experiences . The results do not allow us to determine whether the observed effects are specific to AT or of a nonspecific nature . CONCLUSIONS Our results suggest that AT may have a role in reducing anxiety of patients undergoing coronary angioplasty The present study was design ed to examine the effect of heart rate variability ( HRV ) biofeedback on the cardiorespiratory resting function during sleep in daily life . Forty 
    Output:
    
These studies showed that autogenic training decreased anxiety and depression , and increased the high frequency of heart rate variability .
Autogenic training is effective for adults ' stress management , and nurses will be able to effectively perform autogenic training programs for workers ' stress relief at the workplace