***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: Purpose : To compare the course of inflammation after small‐incision cataract surgery with implantation of 1 of 3 types of foldable intraocular lenses ( IOLs ) in eyes with uveitis . Setting : Department of Ophthalmology , University of Vienna , Vienna , Austria . Methods : Seventy‐four eyes with uveitis and cataract and 68 control eyes with cataract were prospect ively selected to receive a foldable hydrophilic acrylic ( Hydroview ® , Bausch & Lomb ) , hydrophobic acrylic ( AcrySof ® , Alcon ) , or silicone ( CeeOn ® 911 , Pharmacia ) IOL . All surgery was performed by the same surgeon using a st and ardized protocol : clear corneal incision , capsulorhexis , phacoemulsification , and in‐the‐bag IOL implantation . Preoperative and postoperative inflammation was evaluated by measuring aqueous flare preoperatively and 1 , 3 , 7 , 28 , 90 , and 180 days after surgery using the Kowa FC‐1000 ® laser flare‐cell meter . All uveitic eyes were in remission for at least 3 months before surgery . Results : In the uveitic eyes , there was no statistically significant difference in the postoperative course of flare and cell among the 3 IOL groups . Six months after surgery in uveitic eyes , flare values reached preoperative levels and the cell count was lower than preoperatively in all 3 IOL groups . Relative flare values were higher in the eyes with uveitis and a CeeOn 911 IOL ; however , the difference between this group and the 2 acrylic IOL groups was not significant . Conclusions : There were no significant differences in inflammation after implantation of foldable IOLs in uveitic eyes . Although absolute flare values and cell counts in eyes with uveitis were higher than in control eyes , primarily because of a damaged blood‐aqueous barrier ( BAB ) , BAB recovery was similar between the 2 groups . The changes in the BAB indicate that foldable IOL implantation is safe in uveitic eyes Purpose : To evaluate the postoperative outcomes in uveitic eyes after phacoemulsification and posterior chamber intraocular lens ( IOL ) implantation .  Setting : Multicenter ( 19 ) international study . Methods : This prospect i ve r and omized comparative interventional case series comprised 140 eyes of 140 patients who had phacoemulsification and implantation of IOLs of various material s :  hydrophobic acrylic ( n = 48 ) , silicone ( n = 44 ) , poly(methyl methacrylate ) ( PMMA ) ( n = 26 ) , or heparin‐surface‐modified PMMA ( HSM PMMA ) ( n = 22 ) . Preoperative and postoperative grading and control of intraocular inflammation were performed . Clinical ly significant observations , visual outcomes , and the incidence of postoperative complications were recorded . Results : At the final follow‐up , 64 eyes ( 46.3 % ) had a best corrected visual acuity of 20/40 or better , an improvement that was highly significant ( P < .0001 ) . One day after surgery , the acrylic group had the lowest inflammation values and the silicone group the highest ( P = .02 ) . The acrylic group continued to have the lowest inflammation grade values until the 3‐month follow‐up . The acrylic and HSM PMMA groups had the lowest incidence of relapses . Posterior capsule opacification developed in 48 eyes ( 34.2 % ) , with the highest incidence in the silicone group . Conclusions : Phacoemulsification with IOL implantation in selected uveitic eyes was safe and effective . Acrylic IOLs provided a better visual outcome and lower complication rate than IOLs of other material Background To compare a hydrophobic and a hydrophilic acrylic single-piece intraocular lens ( IOL ) in uveitis patients with respect to biocompatibility and visual outcome . Methods Prospect i ve , r and omized study in patients with noninfectious uveitis after phacoemulsification and implantation of either a hydrophobic AcrySof ™  ( group 1 , n = 30 )  or a hydrophilic Akreos adapt ™  ( group 2 , n = 30 ) , sharp-edged acrylic IOL . The primary outcome was uveal biocompatibility , detected by giant-cell deposition , anterior chamber cell count and laserflare photometry over a 6-month follow-up period . Secondary outcome measures were capsular biocompatibility , as detected by posterior capsule opacification ( PCO ) , lens epithelial cell outgrowth and Nd : YAG capsulotomies , and visual outcome . Results The groups did not differ with respect to anatomic type of uveitis , immunosuppressive treatment , associated systemic disease , and intraoperative manipulation . The number of giant cells on the anterior IOL surface was higher in group 1 than in group 2 ( p = 0.03 ) . The number of anterior chamber cells , laser flare photometry levels , and uveitis reactivations after surgery did not differ between the groups . After 6 months , the number of patients with PCO development ( p = 1.0 ) and Nd : YAG capsulotomies ( p = 0.21 ) , lens epithelial cell outgrowth , visual outcome and uveitis complications were comparable in both groups . Conclusions Both of the acrylic IOLs used had good uveal and capsular biocompatibility , leading to significant improvement in BCVA in patients with noninfectious uveitis . No obvious differences were detected at 6 months with respect to uveal and capsular biocompatibility and visual outcome OBJECTIVE To assess the outcome of cataract surgery in eyes of patients with uveitis . DESIGN Prospect i ve , noncomparative case series . PARTICIPANTS A total of 90 eyes of 76 patients fulfilled the enrollment criteria . INTERVENTION All patients had their surgery performed using st and ard cataract extraction techniques . Unless contraindicated , preoperative systemic steroids were administered to all patients with posterior disease , chronic anterior uveitis , with known macular edema , and those in whom outcome of cataract surgery on the fellow eye had been poor . RESULTS Patients were divided into those with anterior disease ( n = 53 ) and those with posterior disease ( n = 37 ) . Overall , 81 ( 90 % ) of 90 eyes showed improvement in vision ( median + 4 Snellen lines ) . In those with anterior disease , the development of severe uveitis in the first week postsurgery was associated with a greater incidence of macular edema ( P = 0.014 ) . The single largest diagnosis in those with posterior disease was that of panuveitis ( n = 24 ) . This group showed the poorest visual outcomes in this study . The majority of patients , however , were noted to have visual loss secondary to conditions present before surgery . CONCLUSION Cataract surgery in eyes with uveitis leads to an improvement of vision in the majority of cases . Severe postoperative uveitis is the most common postoperative complication and is associated with a significant risk of macular edema in those with anterior disease . In the posterior group , poor visual outcome after surgery is most commonly the result of preoperative vision-limiting conditions Purpose To compare the clinical results of heparin surface modified ( HSM ) hydrophilic acrylic intraocular lens ( IOL ) with those of hydrophobic acrylic IOL . Methods One hundred patients with cataract were r and omized to receive one of acrylic foldable IOLs after phacoemulsification : HSM hydrophilic acrylic IOL ( n=50 ) BioVue3 ® ( BioVue , OII , Ontario , CA , USA ) and hydrophobic acrylic IOL ( n=50 ) Sensar ® ( AR40e , AMO , Santa Ana , CA , USA ) . Best-corrected visual acuity and refractive error were measured at 1 week , 2 months , 6 months and 12 months after surgery in both IOL groups . To assess posterior capsular opacification ( PCO ) , digital retroillumination image of posterior capsule was analyzed at 12 months using POCOman software . Results Best-corrected visual acuity ( log MAR ) was 0.032±0.082 in BioVue3 ® group and 0.034±0.077 in Sensar ® group at 12 months . There was no statistically significant difference between the two groups ( p=0.554 ) . Refractive error was −0.247±0.821 diopter in BioVue3 ® group and −0.264±0.808 diopter in Sensar ® group at 12 months . There was no statistically significant difference of refractive error between the two groups ( p=0.909 ) . At 12 months , BioVue3 ® IOL group had a lower percentage area and severity of PCO than Sensar ® group . However , it was not statistically significant ( p=0.349 , p=0.288 ) . No Nd : YAG capsulotomy was performed in BioVue3 ® group while it was required in two eyes ( 4.0 % ) in Sensar ® group . Conclusions There was no statistically significant difference of postoperative visual acuity , refractive error and degree of PCO between HSM hydrophilic acrylic IOL and hydrophobic acrylic IOL Purpose . To evaluate various available intraocular lenses ( IOL ) ( PMMA , acrylic , heparin coated PMMA , and silicone ) in patients with cataracta complicata and evaluate IOL tolerance , post-operative inflammation , cystoid macular edema , and posterior capsular opacification(PCO ) requiring Nd : YAG capsulotomy . Design . r and omized , double masked clinical trial . Participants . Patients evaluated in the Ocular Immunology and Uveitis Service of the Massachusetts Eye and Ear Infirmary and deemed to need cataract surgery by st and ard criteria were asked to participate in the clinical trial . Patients had to have a diagnosis of chronic uveitis , which was inactive for 3 months prior to cataract surgery . Results . Acrylic lenses appeared to provide the best overall results when evaluated for post-operative inflammation , PCO rates , visual acuity , and cystoid macular edema ( CME ) ( compared to PMMA , silicone , and heparin coated PMMA ) Purpose : To evaluate the uveal and capsular biocompatibility of hydrophilic acrylic , hydrophobic acrylic , and silicone intraocular lenses ( IOLs ) in eyes with uveitis . Setting : Department of Ophthalmology , University of Vienna , Vienna , Austria . Methods : This prospect i ve study comprised 72 eyes with uveitis and 68 control eyes having phacoemulsification and IOL implantation by 1 surgeon . Patients received 1 of the following IOLs : foldable hydrophilic acrylic ( Hydroview ® , Bausch & Lomb ) , hydrophobic acrylic ( AcrySof ® , Alcon ) , or silicone ( CeeOn ® 911 , Pharmacia ) . Postoperative evaluations were at 1 , 3 , and 7 days and 1 , 3 , and 6 months . Cell reaction was evaluated by specular microscopy of the anterior IOL surface and the anterior and posterior capsule reaction , by biomicroscopy . Results : Small round cell deposition was observed on all IOLs in the immediate postoperative period , especially in eyes with uveitis . This reaction decreased 3 to 6 months after surgery . Although the CeeOn 911 had a higher mean grade of small cells , there was no statistical difference between the 3 IOL types after 6 months in the uveitis and control groups . Foreign‐body giant cells ( FBGCs ) increased after 1 week to 1 month . The AcrySof IOLs had the highest number of FBGCs ; after 6 months , there was a statistically significant difference between the AcrySof and Hydroview uveitis groups ( P = .036 ) and the AcrySof and CeeOn 911 uveitis groups ( P = .003 ) but there was no difference among the 3 IOL types in the control group . Lens epithelial cell outgrowth persisted on the Hydroview IOLs in control eyes and regressed on all 3 IOL types in uveitic eyes and on the AcrySof and CeeOn 911 IOLs in control eyes ( P = .0001 ) . Anterior capsule opacification ( ACO ) was more severe on all IOL types in uveitic eyes and on the CeeOn 911 IOL in control eyes . Posterior capsule opacification ( PCO ) was more severe in uveitic eyes . The Hydroview group had more severe PCO than the AcrySof and the CeeOn 911 groups in uveitis and control eyes . Six months postoperatively , the difference was significant ( P = .0001 ) . There was no significant difference between the AcrySof and CeeOn 911 IOLs . Conclusions : Intraocular lens biocompatibility is inversely related to inflammation .  Hydrophilic acrylic material had good uveal but worse capsular biocompatibility . Hydrophobic acrylic material had lower uveal but better capsular biocompatibility . Silicone showed a higher small cell count ( mild ) and more severe ACO but achieved PCO results comparable to FBGC results and better than those with the AcrySof lens 6 months after surgery . Despite the differences in IOL biocompatibility , all patients benefited from the surgery PURPOSE A heparin surface modified posterior chamber intraocular lens ( IOL ) was compared with a conventional polymethylmethacrylate ( PMMA ) IOL regarding postoper 
    Output:
    
AUTHORS ' CONCLUSIONS Based on the trials identified in this review , there is uncertainty as to which type of IOL provides the best visual and clinical outcomes in people with uveitis undergoing cataract surgery .
However , due to small sample sizes and heterogeneity in outcome reporting , we found insufficient information to assess these and other types of IOL material s for cataract surgery for eyes with uveitis