***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
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    Input: Pain is still an actual problem in dentistry , and a usage of anaesthetics can be still limited , so new ways of caries treatment are still being search ed in order to ease this process both to a patient and a doctor . Efficiency of chemomechanical tooth treatment to children was studied . 30 children within two age groups of 3 - 6 and 7 - 13 years took part in this research , and their teeth with caries were treated in two different ways -- chemomechanical and traditional . Teeth with the same class of cavities were treated . There are presented records about the need of anaesthetics ' usage , cleaning duration and patients ' complaints in this study . Results show that chemomechanical treatment could be as effective as traditional one , causes less pain and lowers the need for anaesthetics . There was noticed less removal of solid tissue cleaning carious cavity OBJECTIVES The purpose of this study was to compare the chemomechanical caries-removal system ( Carisolv ) with high-speed excavation in cavitated occlusal caries of primary molars . Design and setting . The study was a r and omized controlled , clinical trial in which the two techniques were compared in each subject . Participants were chosen from public schools , in Maracaibo County , Zulia State , Venezuela . SAMPLE AND METHODS The sample consisted of 80 primary molars selected from 40 children ( mean age 7.7+/-0.7 years ) . Each patient had at least two contralateral primary molars with cavitated occlusal caries and approximately equal-size access to lesions . The outcome variables were : clinical ly complete caries removal , size of the opening of the cavity , volume of carious tissue removed , pain during caries removal , anaesthesia requested by the patient , caries-removal time , and behaviour and preference of patients . RESULTS All treated molars were clinical ly caries free whichever caries-removal procedure was used . When Carisolv ' was used the final cavity entrance sizes were smaller ( P<0.001 ) and the estimated volume of tissue removed was less ( P<0.001 ) . The time taken for caries removal was three times longer ( 7.51+/-1.83 min , P<0.001 ) . Some pain was reported by seven ( 17.5 % ) participants when Carisolv was used , compared with 16 ( 40 % ) when high-speed excavation was used ( P<0.05 ) . Using the Carisolv method there was a higher proportion of patients with positive behaviour ( P<0.01 ) , and 71.0 % ( P<0.05 ) preferred this treatment . CONCLUSION Carisolv is an effective clinical alternative treatment for the removal of occlusal dentinal caries in cavitated primary molars ; it is more conservative of dental tissue and appeared to be more comfortable for most patients , although the clinical time spent is longer than when using high-speed excavation PURPOSE The purpose of this controlled clinical trial was to compare the working time for caries removal in primary teeth , the need for local anesthesia and patient cooperation , when the chemomechanical Carisolv or the conventional mechanical method were used . METHODS The sample consisted of primary teeth of children who had occlusal or buccal carious lesions into dentin .  High speed and /or low speed were used as the conventional mechanical method of caries removal . The efficiency in caries removal was judged on the basis of clinical criteria . Length of working time , need of local anesthesia , and level of patient cooperation were recorded for both methods . Statistical analysis was performed using the student 's t test and chi-square test . RESULTS Working time with the chemomechanical method was much more prolonged than with the mechanical method ( P < .001 ) , but it did not negatively affect children 's cooperation . Furthermore , the chemomechanical method reduced the need for administration of local anesthesia for Class V cavity preparations . CONCLUSIONS The chemomechanical method , although more prolonged , is effective in caries removal in primary teeth , does not influence children 's cooperation and may reduce the need of local anesthesia in Class V restorations UNLABELLED The change in the concepts of cavity preparation and the development of reliable adhesive material s lead to the development of alternative methods of caries removal . Chemo-mechanical caries removal ( CMCR ) involves the chemical softening of carious dentin , followed by its removal with gentle excavation . OBJECTIVE The present study was conducted to evaluate clinical ly the efficiency of caries removal using a new chemo-mechanical agent ( Papacarie ) compared to the conventional drilling method including the need for local anesthesia , the need for drill , duration of the treatment and the pain reaction . STUDY DESIGN This study was split mouth design . The study was performed on thirty seven bilateral open carious lesions . They were divided into two equal groups according to method of caries removal . In Group I , caries was removed using the Papacarie system and in Group II , caries was removed with the conventional drill . RESULTS The results showed that the Papacarie was as efficient as the drill in caries removal from open carious lesions with no significant difference in the operating time . The new CMCR agent also reduced significantly the need for local anesthesia and the use of drill . In addition , Papacarie was also more comfortable than the traditional rotatory instruments . CONCLUSIONS It was concluded that Papacarie could be an effective caries removal method to treat children , particularly those who present with early childhood caries or management problems Objective . The purpose of this study was to make a clinical comparison of the chemomechanical method for caries removal and the conventional rotary instruments technique when used in children and adolescents . Material and Methods . The study comprised 120 patients aged 3–17 years r and omized into two groups : caries were removed chemomechanically in 60 patients and 60 patients received conventional treatment with rotary instruments . The outcome variables were : clinical ly complete caries removal , pain during caries removal , need for local anesthesia , treatment time , preferences of patients , and clinical success of the restorations during the 12-month evaluation period . Results . Complete caries removal was achieved in 92 % of chemomechanically treated teeth and in all teeth treated with rotary instruments ( p>0.05 ) . The chemomechanical method significantly reduced the need for local anesthesia ( p<0.001 ) . Eighty-five percent of patients treated with Carisolv and 47 % treated with rotary instruments were satisfied with the treatment ( p<0.05 ) . The mean time for chemomechanical caries removal was 11.2±3.3 min and 5.2±2.8 min for caries removal with rotary instruments ( p<0.001 ) . At the end of the 12-month evaluation period , there was no observed influence of the caries removal method on the survival of the restorations . Conclusions . The chemomechanical caries removal technique is an adequate alternative to the conventional rotary instruments method and is advantageous in pediatric dentistry Dental fear is often associated with experience of pain , unpleasant sounds and uncomfortable vibrations caused by dental drills . Therefore patients welcome alternative , less painful excavating methods such as lasers , s and blasters and chemomechanical systems . The aim of this study was to compare a chemomechanical caries removal system ( Carisolv ) to traditional drilling with regard to patient acceptance and time consumption as well as the six-month success rate of fillings . Ninety-two primary teeth in 46 children were included in the study . From this study , the following conclusions can be drawn : patient acceptance of Carisolv-treatment compared to drilling is excellent , since 65 % would choose Carisolv and no one drilling when treated next time . The dentists rated patients ' degree of pain significantly lower in Carisolv situations than in drill situations . Time consumption is significantly higher when excavating with Carisolv ( 6.7 min . ) than with drill ( 3.3 min . ) . The durability of fillings six months after treatment is equal in the two groups The objective of the present study was to assess the efficiency and benefit of a  chemomechanical system for  carious dentin removal , Carisolv , in general practice . A revised caries classification , the site/stage concept , was used to describe the clinical situations of all carious lesions treated . The study was performed by 12 investigators , and 120 carious lesions were treated with Carisolv .  Sixty percent of the cases were treated without anaesthesia , and we found a significant correlation between chemomechanical treatment without anaesthesia and absence of pain ( P=0.01 ) . In 78.3 % of the cases , carious dentin was totally removed  with Carisolv , and in 21.7 % , the dentin treatment was completed by drilling . In cases performed with Carisolv alone , the time required to remove carious dentin was 11.1±9.51 min ( mean±SD ) . Treatment time was equivalent for all sites and increased significantly with each successive stage of lesion progression ( P<0.001 ) . In 82.5 % of cases , the clinicians were  satisfied with Carisolv , and in 99.2 % , so were the patients . We conclude that , using clinical examination methods , Carisolv seems to remove carious dentin at all sites and stages of carious lesions but must be made more efficient for use in general practice Extensive testing for the safety of the GK-101 solution was conducted with experimental animals . An Investigational New Drug permit was awarded by the Food and Drug Administration before clinical studies . Subsequently , two studies --one double-blind and one open -- were conducted to determine the safety and caries-removing efficacy of a 0.05 % solution of N-monochloroglycine ( GK-101 ) on clinical subjects , as well as to study the technique for such a procedure . In the double-blind study , the efficacy , as shown by ratings for caries removal , of GK-101 applied under pressure was significantly greater than that of the placebo solution of normal saline ( P less than 0.01 ) . Both treatment groups were comparable with respect to the age distribution , pretreatment intraoral examination results , and past history . No drug-related reactions were reported by patients in either group . On the basis of caries removal results in the open study , GK-101 solution , in conjunction with the pump system , was found to be effective as determined by the investigator . The caries in all but one of the 61 lesions treated with GK-101 was rated as " total removal " or as " almost total to total " removal . Approximately 77 % of the patients treated with GK-101 experienced neither pain nor an odd taste . Any pain reported was always described as " slight " or " little . " The drug is currently being further tested for safety and efficacy The purpose of this study was to evaluate the clinical efficiency and patient acceptance of the chemomechanical caries removal agent Carisolv ™ in deciduous teeth . Contralateral primary molars of sixteen 7– to 9–year – old patients ( 32 teeth ) were treated with the air – motor and with Carisolv , respectively . Patients replied to a pre– and a postoperative question naire . Complete caries removal ( CCR ) was accomplished in all air – motor sessions . It was not achieved within the time limit of 15 min in 6 ( 37.5 % ) Carisolv sessions . Air  – motor CCR time ranged between 6 and 18 s ( mean : 11.81 s )  . Carisolv CCR time , where accomplished within 15 min , ranged between 6 min 46 s and 13 min 57 s ( mean : 6 min 51 s ) . Preoperatively , the majority of the children reported disliking the drilling , and that they would visit the dentist more often and prefer sitting in the chair longer if they could avoid it . Postoperatively , the majority of the children reported disliking the taste of Carisolv  , estimated Carisolv to have taken longer , would not recommend it to their friends , and preferred the air – motor . In conclusion , Carisolv , although a step forward in terms of solution volume required , is not in a position to replace rotary instruments for caries removal : it did not remove decay completely in one third of our sample ; it was much slower than the air – motor ; it had a chlorine taste/odor our patients disliked AIM To evaluate and compare the efficacy of chemo mechanical ( carie care ) caries removal method with rotary and h and excavation by assessing the amount of time taken , the pain response experienced by the children and the amount of residual caries left out . STUDY DESIGN Twenty patients between the age groups of 5 - 7 years were selected and caries removal was done by airotor h and instruments and cariecare gel . The efficacy , time taken and pain threshold was evaluated during caries removal . RESULTS significant results were obtained when inter group comparison were made . CONCLUSION it was concluded that cariecare was efficient in caries removal and can be used as an alternative for the airotor in management of dental caries especially in children 
    Output:
    
This systematic review indicates that the clinical efficacy of chemo-mechanical removal with Carisolv seems as reliable as the rotary instruments .