***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: BACKGROUND Female patients are underrepresented in most  stent-graft ( EVAR ) trials due to a reduced anatomical eligibility for endovascular treatment . The purpose of this analysis was to determine the performance of the Ovation ® and Ovation Prime ® stent graft in women versus men for elective abdominal aortic aneurysm ( AAA ) repair . METHODS From May 2011 to December 2013 , 501 patients ( 86 % men , mean age 73 years ) from 30 sites were prospect ively enrolled in the OVATION Registry and electively treated with endovascular aneurysm repair .  Patients returned for clinical and imaging follow-up at 1 month , 6 months , and 1 year . A post-hoc analysis was performed to assess the influence of gender on patient outcomes . RESULTS Women were older ( median 77 vs. 73 years , P<0.01 ) although men reported a higher frequency of ASA class III/IV ( 54 % vs. 34 % ) , coronary artery disease ( 43 % vs. 29 % ) , diabetes mellitus ( 19 % vs. 7 % ) , and history of tobacco use ( 50 % vs. 33 % ) . Median external iliac diameter was 6.4 mm in women and 7.5 mm in men ( P<0.001 ) . Proximal neck diameter was larger in men versus women ( 24 vs. 22 mm ) . Technical success was 100 % in women and 99.5 % in men . Type I endoleak was identified in 5 men ( 1.5 % ) and a type III leak was identified in 1 ( 0.3 % ) man . No woman presented with type I or III endoleak at 1 year . The rate of AAA enlargement was similar in women ( 2.5 % ) and men ( 2.7 % ) . Freedom from aneurysm-related mortality through 1 year was 100 % in women and 99.3 % in men ( log-rank P=0.49 ) . Freedom from all-cause mortality through 1 year was 94.0 % in women and 95.8 % in men ( log-rank P=0.51 ) . One contained AAA rupture was reported in a male patient . One female patient underwent conversion to open surgery . Freedom from a secondary intervention through 1 year was 88.2 % in women and 93.7 % in men ( log-rank P=0.11 ) . CONCLUSIONS Women and men derive similarly favorable benefits with the Ovation stent graft through 1-year follow-up . Longer-term follow-up will be required to determine the durability of these outcomes OBJECTIVE Women have been under-represented in trials that set guidelines for the management of aortic aneurysms . Several studies reported inferior outcomes in women compared with men after endovascular aneurysm repair ( EVAR ) .  We investigated the relationship between gender and outcomes after EVAR . METHODS A total of 1380 consecutive patients underwent elective EVAR from 1992 to 2012 . Baseline , intraoperative , and postoperative variables by gender were analyzed from a prospect i ve data base . RESULTS The cohort comprised 214 women ( 15.5 % ) and 1166 men ( 84.5 % ) . Women were older than men at repair ( 77.8 vs 74.5 years , P < .001 ) and had less cardiac disease ( P = .005 ) . They had shorter ( 19.8 ± 12.9 vs 26.3 ± 14.7 mm ; P < .001 ) more angulated aortic necks ( 38.8 ° ± 16.1 ° vs 31.2 ° ± 14.7 ° ; P < .001 ) and fewer iliac aneurysms ( P = .002 ) . Women had more arterial reconstructions ( iliac conduits , P = .006 ; thrombolysis and thrombectomy , P = .013 ; patch angioplasty , P < .001 ; endarterectomy , P < .001 ) , more perioperative complications ( 16.9 % vs 9.1 % ; P = .001 ) , and more in-hospital days ( 4.1 vs 3.4 days ; P = .029 ) . Perioperative mortality was equivalent ( women : 2 % vs men : 2.3 % ; P = .73 ) . Mean follow-up was 30.9 months . Women and men experienced equivalent aneurysm-related deaths and overall survival . Survival curve analysis showed endoleaks were more likely to develop in women than men ( P = .005 ) ; however , there was no difference in rates of arterial re interventions required for each gender during the follow-up period . CONCLUSIONS Female gender is associated with more periprocedural complications , adjunctive arterial procedures , and increased endoleaks but does not affect long-term re interventions or survival . Further studies are warranted to eluci date the effect of gender on outcomes . These data should be considered when selecting EVAR for men and women AIM It is widely known that inflammation is related to type 2 diabetes ( T2D ) , but few studies have shown a direct relationship between the immune system and T2D using a reliable biomarker . Neutrophil : lymphocyte ratio ( NLR ) is an easy-to-analyze inflammation biomarker , but few studies have assessed the relationship between NLR and T2D . In order to evaluate how NLR is related to T2D , we design ed a large-scale cross-sectional and prospect i ve cohort study in an adult population . SUBJECTS AND METHODS Participants were recruited from the Tianjin Medical University General Hospital-Health Management Centre . Both a baseline cross-sectional ( n=87,686 ) and a prospect i ve ( n=38,074 ) assessment were performed . Participants without a history of T2D were followed up for ∼ 6 years ( with a median follow-up of 2.7 years ) . Adjusted logistic and Cox proportional hazards regression models were used to assess relationships between the quintiles of NLR and T2D ( covariates : age , sex , BMI , smoking status , drinking status , hypertension , hyperlipidemia , and family history of cardiovascular disease , hypertension , hyperlipidemia , or diabetes ) . RESULTS The prevalence and incidence of T2D were 4.9 % and 6.8/1000 person-years respectively . The adjusted odds ratio and hazard ratio ( 95 % CI ) of the highest NLR quintile were 1.34 ( 1.21 , 1.49 ) and 1.39 ( 1.09 , 1.78 ) ( both P for trend < 0.01 ) respectively as compared to the lowest quintile of NLR . Leukocyte , neutrophil , and lymphocyte counts do not significantly predict the eventual development of T2D . CONCLUSION The present study demonstrates that NLR is related to the prevalence and incidence of T2D , and it suggests that NLR may be an efficient and accurate prognostic biomarker for T2D 
    Output:
    
Li J , Chen Q , Luo X , Hong J , Pan K , Lin X , et al. Neutrophil-tolymphocyte ratio positively correlates to age in healthy population .
Reference value of neutrophil lymphocyte ratio in healthy Sudanese in Khartoum .