***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: OBJECTIVE Chronic gastritis was treated with herbal pairs in order to reduce the side effects and raise the therapeutic effects . METHOD The out patients were r and omly divided into a treatment group treated with herbal pairs and a control group treated with Banxia Xiexin Tang ( Pinellia Decoction for Purging the Stomach-fire ) . RESULT The total effective rate in the treatment group was 96 % , higher than that in the control group ( P < 0.05 ) . CONCLUSION With the basic theory of traditional Chinese medicine as guiding principles , herbal pairs have two-way regulatory effects , that is , reducing the side effects and raising the therapeutic effects Kang Wei Granules , a granular preparation for strengthening the spleen and replenishing Qi and for clearing away heat and resolving dampness , was used in the treatment of 288 cases of gastropathy related to Helicobacter pylori infection . The effects were compared with De Nol triple therapy in the control group of 74 cases . The therapeutic results showed that Kang Wei Granules was superior to the western drugs in improving the principal symptoms of deficiency of the spleen and stomach , and retention of damp-heat in the interior ( P < 0.05 ) AIM To document the efficacy and tolerability of 14-day moxifloxacine-tetracycline-lansoprazole ( MTL ) regimens for  Helicobacter pylori ( Hp ) eradication as a first-line therapy . METHOD Fifty-six Hp-positive patients were enrolled . Patients were considered eligible for the study if they underwent upper gastrointestinal endoscopy , and Hp infection was diagnosed through histologic examination of antral and body bioptic sample s. Primary end point of this study was to evaluate the eradication rate of 14-day MTL regimen therapies . Hp eradication was assessed using the 13C urea breath test performed . All patients were asked to fill in a vali date d question naire to report therapy-related side effects . Each symptom was grade d from absent or present . RESULTS Fifty-six patients ( 29 men and 27 women ) were enrolled . The studied therapeutic regimens were completed by 96.4 % patients . Two dropouts occurred in the MTL group because of side effects . The eradication rate in MTL regimens was 55.4 % . The overall prevalence of side effects was high in the MTL group . CONCLUSION The MTL regimen failed to achieve the recommended eradication rates and had higher adverse effect rate . Hence , MTL regimen does not seem to be a suitable choice as a first-line Hp eradication therapy AIM The eradication rate of Helicobacter pylori ( H pylori ) shows variation among countries and regimens of treatment . We aim ed to study the eradication rates of different regimens in our region and some factors affecting the rate of eradication . METHODS One hundred and sixty-four H pylori positive patients ( 68 males , 96 females ; mean age : 48+/-12 years ) with duodenal or gastric ulcer without a smoking history were included in the study . The patients were divided into three groups according to the treatment regimens . Omeprazole 20 mg , clarithromycin 500 mg , amoxicillin 1 g were given twice daily for 1 week ( Group I ) and 2 weeks ( Group II ) . Patients in Group III received bismuth subsitrate 300 mg , tetracyline 500 mg and metronidazole 500 mg four times daily in addition to Omeprazole 20 mg twice daily . Two biopsies each before and after treatment were obtained from antrum and corpus , and histopathologically evaluated . Eradication was assumed to be successful if no H pylorus was detected from four biopsy specimens taken after treatment . The effects of factors like age , sex , H pylori density on antrum and corpus before treatment , the total H pylori density , and the inflammation scores on the rate of H pylori eradication were evaluated . RESULTS The overall eradication rate was 42 % . The rates in groups II and III were statistically higher than that in group I ( P<0.05 ) . The rates of eradication were 24.5 % , 40.7 % and 61.5 % in groups I , II and III , respectively . The eradication rate was negatively related to either corpus H pylori density or total H pylori density ( P<0.05 ) . The median age was older in the group in which the eradication failed in comparison to that with successful eradication ( 55 yr vs 39 yr , P<0.001 ) . No correlation between sex and H pylori eradication was found . CONCLUSION Our rates of eradication were significantly lower when compared to those reported in literature . We believe that advanced age and high H pylori density are negative predictive factors for the rate of H pylori eradication Objective To assess the efficacy and safety of Moluodan ( 摩罗丹 ) in treating dysplasia in chronic atrophic gastritis ( CAG ) patients . Methods This was a multi-centered , double-blind , r and omized controlled trial . The total of 196 subjects were assigned to receive either Moluodan or folic acid in a 2:1 ratio by blocked r and omization . Mucosa marking targeting biopsy ( MTB ) was used to insure the accuracy and consistency between baseline and after 6-month treatment . Primary outcomes were histological score , response rate of pathological lesions and dysplasia disappearance rate . Secondary endpoints included gastroscopic findings , clinical symptom and patient reported outcome ( PRO ) instrument . Results Dysplasia score decreased in Moluodan group ( P = 0.002 ) , significance was found between groups ( P = 0.045 ) . Dysplasia disappearance rates were 24.6 % and 15.2 % in Moluodan and folic acid groups respectively , no significant differences were found ( P = 0.127 ) . The response rate of atrophy and intestinal metaplasia were 34.6 % and 23.0 % in Moluodan group , 24.3 % and 13.6 % in folic acid group . Moluodan could improve erythema ( P = 0.044 ) , and bile reflux ( P = 0.059 ) , no significance between groups . Moluodan was better than folic acid in improving epigastric pain , epigastric suffocation , belching and decreased appetite ( P < 0.05 ) , with symptom disappearance rates of 37 % to 83 % . Conclusions Moluodan  improved dysplasia score in histopathology , and erythema and bile reflux score in endoscopy , and superior to folic acid in improving epigastric pain , epigastric suffocation , belching and decreased appetite . [ ChiCTR-TRC-00000169 
    Output:
    
CHD , if prescribed as a complementary therapy to WM , may improve the clinical manifestations and pathological change for AG patients .
But its monotherapy for H. pylori eradication is not supported by enough clinical evidence