***TASK*** the task is to summarize an input biomedical literature in six sentences 
    ***INPUT*** the input is a biomedical literature 
    ***OUTPUT*** the output is the summary of an input biomedical literature in six sentences 
    ***DOCUMENTATION*** 
    ***EXAMPLES*** 
    Input: This study was design ed to compare differentprimer sets for PCR analysis of H. pylori in the sameseries of 40 dental plaque sample s. Three pairs ofprimers , HPU1/HPU2 , HP1/HP2 , and EHC-U/EHC-L , directed to the urease A gene , 16S rRNA gene , or 860-bpDNA of H. pylori , respectively , were used . Our results demonstrate that EHC-L/EHC-U were moRespecific and sensitive for H. pylori added to saliva or dental plaque than HPU1/HPU2 and HP1/HP2 . Thedetection rates for H. pylori DNA in dental plaque sample s from r and omly selected adult patients from theDental Clinic of the University of Ulm were 26.5 % ( 9/34 ) for HPU1/HPU2 , 78.9 % ( 30/38 ) for HP1/HP2 , and 100 % ( 40/40 ) for EHC-U/EHC-L ( P < 0.001 ) . Nested PCRusing primers directed to the 860-bp DNA of H. pylorifurThe r confirmed the presence of H. pylori DNA ( 40/40 ) in all these sample s. Our results indicate that primers EHC-U/EHC-L are to be recommendedfor PCR detection of H. pylori in the oralcavity The objective of this study is to determine the presence of Helicobacter pylori in the dental plaque of healthy Saudis and its relation to dental care . One hundred r and omly selected healthy Saudis attending the dental clinic were assessed for oral hygiene and periodontal disease by dental examination . Information about the use of toothpaste , chewing stick , smoking and dentures was obtained . Sample s of dental plaque were collected after scoring it according to the plaque index . Presence of H. pylori in the plaque was sought by a commercially available rapid urease test with a sensitivity of 94 % and a specificity of 100 % . The presence of H. pylori was indicated by a positive rapid urease test in 81 % . There was significant correlation of heavy dental plaque ( plaque index score 3 ) with presence of H. pylori ( p=0.03 ) . We conclude that H. pylori is present in the dental plaque of most Saudis and this is due to poor oral hygiene BACKGROUND Helicobacter pylori eradication from the oral cavity is more difficult than from the stomach . Thus , if the bacterium survives the antibacterial therapy in the oral cavity , it would be able to re-infect the stomach within a few weeks . Since oral health status could correspond to oral infection with H. pylori , the aim of the study was to determine whether oral health and oral hygiene practice s affect the efficacy of H. pylori eradication from the stomach . MATERIAL AND METHODS The study was performed in 137 patients with peptic ulcer who had undergone a 7-day course of eradication treatment with one of two sets of drugs : 1 , omeprazole , amoxicillin , and tinidazole or 2 , omeprazole , clarithromycin , and tinidazole .  The efficacy of H. pylori eradication from the stomach was evaluated at the second gastroscopy 4 weeks after cessation of eradication therapy by means of two methods : rapid urease test and histology . The examination of natural dentition and prosthetic restorations as well as the assessment of hygienic procedures referring to natural dentition and dentures accompanied the second gastroscopy . RESULTS No association was found between the efficacy of H. pylori eradication from the stomach and the number of natural teeth , decayed teeth , use of dentures , debris index , or periodontal index . However , an association between eradication success and some oral hygiene procedures were noted . Unexpectedly , in patients treated with omeprazole , amoxicillin and tinidazole , the removal of dental prosthesis for the night and brushing the natural teeth twice a day or more reduced the efficacy of H. pylori eradication from the stomach . CONCLUSIONS Oral health and oral hygiene practice s seem unlikely to increase the efficacy of H. pylori eradication from the stomach 
    Output:
    
Based on the systematic review of the available literature on H. pylori infection and its presence in the oral cavity , it can be concluded that dental plaque can act as a reservoir , and proper oral hygiene maintenance is essential to prevent reinfection .