human
The task is to decide the Hallmarks of Cancer (HOC) taxonomy of the article based on its abstract. The input is an abstract text. There are 10 topics you will need to decide whether the article is related to. Topics: sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, genomic instability and mutation, tumor promoting inflammation, cellular energetics, avoiding immune destruction. The output should be topics from the above 10 topics, that are related to the input article. Please note one article can be related to multiple topics. Output format: provide a semicolon-separated list of relevant topics.
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    INPUT: Sarcomatoid renal cell carcinomas of the kidney are rare neoplasms constituting about 1-5% of all renal malignant neoplasms . These are aggressive tumors and are commonly associated with conventional ( clear cell ) renal cell carcinomas , but cases associated with chromophobe renal cell carcinomas are sparse . Cytological features of such lesions have rarely been reported . Here , we report a unique case of a 48-year-old male patient who presented with right flank lump and pain . A fine needle aspiration was performed from the lesion under ultrasound guidance and a cytological diagnosis of pleomorphic sarcoma was made . A right-sided radical nephrectomy was carried out and subsequent histopathology revealed a sarcomatoid renal cell carcinoma with wide areas of necrosis coexisting with chromophobe renal cell carcinoma with calcification . Differentiation of pleomorphic sarcoma from a sarcomatoid renal cell carcinoma is , thus , challenging from cytopathology smears and the differential diagnoses should always be borne in mind while giving a cytopathological opinion .
    OUTPUT:

agent
resisting cell death
The task is to decide the Hallmarks of Cancer (HOC) taxonomy of the article based on its abstract. The input is an abstract text. There are 10 topics you will need to decide whether the article is related to. Topics: sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, activating invasion and metastasis, genomic instability and mutation, tumor promoting inflammation, cellular energetics, avoiding immune destruction. The output should be topics from the above 10 topics, that are related to the input article. Please note one article can be related to multiple topics. Output format: provide a semicolon-separated list of relevant topics.
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    INPUT: Sarcomatoid renal cell carcinomas of the kidney are rare neoplasms constituting about 1-5% of all renal malignant neoplasms . These are aggressive tumors and are commonly associated with conventional ( clear cell ) renal cell carcinomas , but cases associated with chromophobe renal cell carcinomas are sparse . Cytological features of such lesions have rarely been reported . Here , we report a unique case of a 48-year-old male patient who presented with right flank lump and pain . A fine needle aspiration was performed from the lesion under ultrasound guidance and a cytological diagnosis of pleomorphic sarcoma was made . A right-sided radical nephrectomy was carried out and subsequent histopathology revealed a sarcomatoid renal cell carcinoma with wide areas of necrosis coexisting with chromophobe renal cell carcinoma with calcification . Differentiation of pleomorphic sarcoma from a sarcomatoid renal cell carcinoma is , thus , challenging from cytopathology smears and the differential diagnoses should always be borne in mind while giving a cytopathological opinion .
    OUTPUT:
