***TASK***
the task is to simplify the input abstract of a biomedical literature

***INPUT***
the input is the abstract of a biomedical literature

***OUTPUT***
the output is the simplified abstract for the input abstract of a biomedical literature

***DOCUMENTATION***

***EXAMPLES***

Input: We included a single-centre non-blinded randomised controlled trial that reported a total of 302 intubation attempts in 232 infants. The median gestational age of enrolled infants was 29 weeks. Paediatric residents and fellows performed the intubations. We judged the study to be at low risk of bias overall. Investigators compared success rates of first-attempt intubation with and without use of a stylet and reported success rates as similar between stylet and no-stylet groups (57% and 53%) (P = 0.47). Success rates did not differ between groups in subgroup analyses by provider level of training and infant weight. Results showed no differences in secondary review outcomes, including duration of intubation, number of attempts, participant instability during the procedure, and local airway trauma. Only 25% of all intubations took less than 30 seconds to perform. Study authors did not report neonatal morbidity nor mortality. We considered the quality of evidence as low on GRADE analysis, given that we identified only one unblinded study. Current available evidence suggests that use of a stylet during neonatal orotracheal intubation does not significantly improve the success rate among paediatric trainees. However, only one brand of stylet and one brand of endotracheal tube have been tested, and researchers performed all intubations on infants in a hospital setting. Therefore, our results cannot be generalised beyond these limitations.
Output:

In literature searches updated in April 2017, we found one randomised controlled trial (302 intubations) that met the inclusion criteria of this review. Rates of successful intubation at first attempt with or without use of a stylet as an aid were similar, at 57% and 53%, respectively. Success rates with and without use of a stylet did not differ between infants of different weights, or between trainee paediatric doctors with different levels of experience. The length of time it took to intubate and the number of attempts made before successful intubation were comparable between groups. The incidence of a drop in a patient’s oxygen level and in heart rate was equivalent between groups, as was the reported incidence of trauma to the airway associated with the procedure. The quality of evidence was low. We downgraded the level because we included only one unblinded study.