***TASK***
the task is to simplify the input abstract of a biomedical literature

***INPUT***
the input is the abstract of a biomedical literature

***OUTPUT***
the output is the simplified abstract for the input abstract of a biomedical literature

***DOCUMENTATION***

***EXAMPLES***

Input: We included 30 studies, which evaluated 3D exercise (Tai Chi and yoga), balance training or strength and resistance training. Two of these were cluster-randomised trials, two were cross-over trials and one was quasi-randomised. The studies included a total of 2878 participants with a mean age ranging from 68 to 85 years. Most studies included more women than men, with four studies recruiting women only. Twelve studies recruited participants at increased risk of falls; three of these recruited participants who also had fear of falling. Poor reporting of the allocation methods in the trials made it difficult to assess the risk of selection bias in most studies. All of the studies were at high risk of performance and detection biases as there was no blinding of participants and outcome assessors and the outcomes were self reported. Twelve studies were at high risk of attrition bias. Using GRADE criteria, we judged the quality of evidence to be 'low' for fear of falling immediately post intervention and 'very low' for fear of falling at short or long-term follow-up and all other outcomes. Exercise interventions were associated with a small to moderate reduction in fear of falling immediately post intervention (SMD 0.37 favouring exercise, 95% confidence interval (CI) 0.18 to 0.56; 24 studies; 1692 participants, low quality evidence). Pooled effect sizes did not differ significantly between the different scales used to measure fear of falling. Although none of the sensitivity analyses changed the direction of effect, the greatest reduction in the size of the effect was on removal of an extreme outlier study with 73 participants (SMD 0.24 favouring exercise, 95% CI 0.12 to 0.36). None of our subgroup analyses provided robust evidence of differences in effect in terms of either the study primary aim (reduction of fear of falling or other aim), the study population (recruitment on the basis of increased falls risk or not), the characteristics of the study exercise intervention or the study control intervention (no treatment or alternative intervention). However, there was some weak evidence of a smaller effect, which included no reduction, of exercise when compared with an alternative control. There was very low quality evidence that exercise interventions may be associated with a small reduction in fear of falling up to six months post intervention (SMD 0.17, 95% CI -0.05 to 0.38; four studies, 356 participants) and more than six months post intervention (SMD 0.20, 95% CI -0.01 to 0.41; three studies, 386 participants). Very low quality evidence suggests exercise interventions in these studies that also reported on fear of falling reduced the risk of falling measured either as participants incurring at least one fall during follow-up or the number of falls during follow-up. Very low quality evidence from four studies indicated that exercise interventions did not appear to reduce symptoms of depression or increase physical activity. The only study reporting the effects of exercise interventions on anxiety found no difference between groups. No studies reported the effects of exercise interventions on activity avoidance or costs. It is important to remember that our included studies do not represent the totality of the evidence of the effect of exercise interventions on falls, depression, anxiety or physical activity as our review only includes studies that reported fear of falling. Exercise interventions in community-dwelling older people probably reduce fear of falling to a limited extent immediately after the intervention, without increasing the risk or frequency of falls. There is insufficient evidence to determine whether exercise interventions reduce fear of falling beyond the end of the intervention or their effect on other outcomes. Although further evidence from well-designed randomised trials is required, priority should be given to establishing a core set of outcomes that includes fear of falling for all trials examining the effects of exercise interventions in older people living in the community.
Output:

We searched the medical literature up to July 2013 for studies that tested the effects of exercise and reported fear of falling in community-dwelling people (i.e. who live either at home or in places of residence that do not provide nursing care or rehabilitation) aged 65 years and older. The studies compared exercise with no treatment or an alternative intervention, such as education. Summary of the evidence We included 30 studies in the review, with a total of 2878 participants whose average age ranged from 68 to 85 years. Most studies recruited mainly women. Twelve studies recruited participants at increased risk of falls and three of these recruited people who also had fear of falling. All of the studies were at some risk of bias mainly because the participants were aware what group they were in. This lack of blinding may have influenced the study results. We found low quality evidence from 24 studies that exercise interventions result in a small to moderate reduction in fear of falling immediately after the intervention. Some exploratory analyses did not enable us to determine whether this effect differed in different groups of people, such as those at high risk of falling, or with different exercise interventions, such as group or individual exercise. We are very unsure that the effect of exercise on fear of falling is maintained in the next few months after the end of the intervention. We only included studies that reported fear of falling, therefore the evidence on our other outcomes (occurrence of falls, depression, anxiety and physical activity) is only a small part of the total evidence of the effects of exercise on these outcomes. However, the evidence from nine studies included in our review showing that exercise reduced the risk and number of falls is consistent with the results of another Cochrane review testing the effects of exercise on preventing falls. The evidence on the other outcomes was far less and none of the included studies reported the effects of exercise interventions on activity avoidance or costs. Conclusion We concluded that exercise interventions in community-dwelling older people probably reduce fear of falling to a limited extent immediately after the intervention, without increasing the risk or frequency of falls. We also concluded that there is not enough evidence to determine whether exercise interventions reduce fear of falling beyond the end of the intervention or their effect on other outcomes. We encourage further research on this topic.