In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The Calcineurin - inhibitor Induced Pain Syndrome ( CIPS ) is a rare but severe side effect of cyclosporine or tacrolimus and is accurately diagnosed by its typical presentation , magnetic resonance imaging and bone scans .
### Output Text:
The Calcineurin - inhibitor Induced Pain Syndrome ( CIPS ) is a rare but severe side effect of <span class="chemical">cyclosporine</span> or <span class="chemical">tacrolimus</span> and is accurately diagnosed by its typical presentation , magnetic resonance imaging and bone scans . 