In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Our findings show that long - term treatment with high doses of ketoconazole may induce enzyme blockade leading to mineralocorticoid - related hypertension .
### Output Text:
Our findings show that long - term treatment with high doses of <span class="chemical">ketoconazole</span> may induce enzyme blockade leading to mineralocorticoid - related hypertension . 