In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: However , TAM induces release of peripheral proteins of membrane - cytoskeleton and cytosol proteins essentially bound to band 3 .
### Output Text:
However , <span class="chemical">TAM</span> induces release of peripheral proteins of membrane - cytoskeleton and cytosol proteins essentially bound to band 3 . 