In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: One of the latter two patients further experienced a cytolytic hepatitis which appeared after Benzylthiouracil ( Basd ne ) had replaced carbimazole .
### Output Text:
One of the latter two patients further experienced a cytolytic hepatitis which appeared after <span class="chemical">Benzylthiouracil</span> ( <span class="chemical">Basd ne</span> ) had replaced <span class="chemical">carbimazole</span> . 