In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: On the first day of the schedule , moderate high doses of Methotrexate , Etoposide and Cyclophosphamide were administered .
### Output Text:
On the first day of the schedule , moderate high doses of <span class="chemical">Methotrexate</span> , <span class="chemical">Etoposide</span> and <span class="chemical">Cyclophosphamide</span> were administered . 