In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: In addition , PD female rats showed increased ( 3 ) H - MK - 801 binding in the striatum and hippocampus , but not in the cortex .
### Output Text:
In addition , PD female rats showed increased ( 3 ) <span class="chemical">H</span> - <span class="chemical">MK - 801</span> binding in the striatum and hippocampus , but not in the cortex . 