In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Adult male albino rats , treated with ISO ( 200 mg / kg , s . c . ) for 2 days at an interval of 24 h caused a significant ( P < 0 . 05 ) elevation of heart weight , serum marker enzymes , lipid peroxidation and Ca + 2 ATPase level whereas there was a significant ( P < 0 . 05 ) decrease in body weight , endogenous antioxidants , Na + / K + ATPase and Mg + 2 ATPase levels .
### Output Text:
Adult male albino rats , treated with <span class="chemical">ISO</span> ( 200 mg / kg , s . c . ) for 2 days at an interval of 24 h caused a significant ( P < 0 . 05 ) elevation of heart weight , serum marker enzymes , lipid peroxidation and <span class="chemical">Ca</span> + 2 ATPase level whereas there was a significant ( P < 0 . 05 ) decrease in body weight , endogenous antioxidants , <span class="chemical">Na</span> + / <span class="chemical">K</span> + ATPase and <span class="chemical">Mg</span> + 2 ATPase levels . 