In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: CONCLUSIONS : The rate of contrast - induced nephropathy , defined by multiple end points , is not statistically different after the intraarterial administration of iopamidol or iodixanol to high - risk patients , with or without diabetes mellitus .
### Output Text:
CONCLUSIONS : The rate of contrast - induced nephropathy , defined by multiple end points , is not statistically different after the intraarterial administration of <span class="chemical">iopamidol</span> or <span class="chemical">iodixanol</span> to high - risk patients , with or without diabetes mellitus . 