In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Clonidine - induced bradycardia in conscious alpha2ABC - / - mice was 32 . 3 % ( 10 microg / kg ) and 26 . 6 % ( 100 microg / kg ) of the effect in wild - type mice .
### Output Text:
<span class="chemical">Clonidine</span> - induced bradycardia in conscious alpha2ABC - / - mice was 32 . 3 % ( 10 microg / kg ) and 26 . 6 % ( 100 microg / kg ) of the effect in wild - type mice . 