In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The multiple drug schema consisted of : Etoposide 16 . 213 , Methotrexate , Cyclophosphamide , Actomycin - D , and Cisplatin .
### Output Text:
The multiple drug schema consisted of : <span class="chemical">Etoposide</span> 16 . 213 , <span class="chemical">Methotrexate</span> , <span class="chemical">Cyclophosphamide</span> , <span class="chemical">Actomycin - D</span> , and <span class="chemical">Cisplatin</span> . 