In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: NRA0160 , 5 - [ 2 - ( 4 - ( 3 - fluorobenzylidene ) piperidin - 1 - yl ) ethyl ] - 4 - ( 4 - fluorophenyl ) thiazole - 2 - carboxamide , has a high affinity for human cloned dopamine D4 . 2 , D4 . 4 and D4 . 7 receptors , with Ki values of 0 . 5 , 0 . 9 and 2 . 7 nM , respectively .
### Output Text:
<span class="chemical">NRA0160</span> , <span class="chemical">5 - [ 2 - ( 4 - ( 3 - fluorobenzylidene ) piperidin - 1 - yl ) ethyl ] - 4 - ( 4 - fluorophenyl ) thiazole - 2 - carboxamide</span> , has a high affinity for human cloned <span class="chemical">dopamine</span> D4 . 2 , D4 . 4 and D4 . 7 receptors , with Ki values of 0 . 5 , 0 . 9 and 2 . 7 nM , respectively . 