In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Brain MR studies , including DW imaging , were prospectively performed in 14 organ transplant patients receiving tacrolimus who developed neurologic complications .
### Output Text:
Brain MR studies , including DW imaging , were prospectively performed in 14 organ transplant patients receiving <span class="chemical">tacrolimus</span> who developed neurologic complications . 