In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The semi - quantitative scoring was significantly worst in the group treated with CsA plus SRL ( P < 0 . 001 compared with controls ) and the analysis of the total grade of fibrosis also showed the highest proportion in the same group and was significantly different from controls ( P < 0 . 02 ) .
### Output Text:
The semi - quantitative scoring was significantly worst in the group treated with <span class="chemical">CsA</span> plus <span class="chemical">SRL</span> ( P < 0 . 001 compared with controls ) and the analysis of the total grade of fibrosis also showed the highest proportion in the same group and was significantly different from controls ( P < 0 . 02 ) . 