In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: This study assessed the ability of IH636 grape seed proanthocyanidin extract ( GSPE ) to prevent acetaminophen ( AAP ) - induced nephrotoxicity , amiodarone ( AMI ) - induced lung toxicity , and doxorubicin ( DOX ) - induced cardiotoxicity in mice .
### Output Text:
This study assessed the ability of <span class="chemical">IH636 grape seed proanthocyanidin extract</span> ( <span class="chemical">GSPE</span> ) to prevent <span class="chemical">acetaminophen</span> ( <span class="chemical">AAP</span> ) - induced nephrotoxicity , <span class="chemical">amiodarone</span> ( <span class="chemical">AMI</span> ) - induced lung toxicity , and <span class="chemical">doxorubicin</span> ( <span class="chemical">DOX</span> ) - induced cardiotoxicity in mice . 