In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: A decreased glutamate uptake was observed in the subcortical parts of animals treated with reserpine and haloperidol , compared to the control .
### Output Text:
A decreased <span class="chemical">glutamate</span> uptake was observed in the subcortical parts of animals treated with <span class="chemical">reserpine</span> and <span class="chemical">haloperidol</span> , compared to the control . 