In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: End - stage renal disease ( ESRD ) after orthotopic liver transplantation ( OLTX ) using calcineurin - based immunotherapy : risk of development and treatment .
### Output Text:
End - stage renal disease ( ESRD ) after orthotopic liver transplantation ( OLTX ) using calcineurin - based immunotherapy : risk of development and treatment . 