In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Serum - and glucocorticoid - inducible kinase 1 in doxorubicin - induced nephrotic syndrome .
### Output Text:
Serum - and glucocorticoid - inducible kinase 1 in <span class="chemical">doxorubicin</span> - induced nephrotic syndrome . 