In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Kidney function and morphology after short - term combination therapy with cyclosporine A , tacrolimus and sirolimus in the rat .
### Output Text:
Kidney function and morphology after short - term combination therapy with <span class="chemical">cyclosporine A</span> , <span class="chemical">tacrolimus</span> and <span class="chemical">sirolimus</span> in the rat . 