In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: CONCLUSION : Our results suggest that high - dose testosterone therapy may adversely affect atherosclerosis in postmenopausal women and indicate that androgen replacement in these women may not be harmless .
### Output Text:
CONCLUSION : Our results suggest that high - dose <span class="chemical">testosterone</span> therapy may adversely affect atherosclerosis in postmenopausal women and indicate that androgen replacement in these women may not be harmless . 