In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Ezetimibe undergoes extensive glucuronidation by uridine diphosphate glucoronosyltransferases ( UGT ) in the intestine and liver and may have inhibited the glucuronidation of simvastatin hydroxy acid , resulting in increased simvastatin exposure and subsequent hepatotoxicity .
### Output Text:
<span class="chemical">Ezetimibe</span> undergoes extensive glucuronidation by <span class="chemical">uridine diphosphate</span> glucoronosyltransferases ( UGT ) in the intestine and liver and may have inhibited the glucuronidation of <span class="chemical">simvastatin hydroxy acid</span> , resulting in increased <span class="chemical">simvastatin</span> exposure and subsequent hepatotoxicity . 