In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: EBFF did not change during PGE1 infusion whereas in the TMP group , EBF decreased significantly at 30 and 60 min after the start of TMP ( preinfusion : 45 . 9 + / - 13 . 9 ml / 100g / min . 30 min : 32 . 3 + / - 9 . 9 ml / 100 g / min ( P < 0 . 05 ) . 60 min : 30 + / - 7 . 5 ml / 100 g / min ( P < 0 . 05 ) ) .
### Output Text:
EBFF did not change during <span class="chemical">PGE1</span> infusion whereas in the <span class="chemical">TMP</span> group , EBF decreased significantly at 30 and 60 min after the start of <span class="chemical">TMP</span> ( preinfusion : 45 . 9 + / - 13 . 9 ml / 100g / min . 30 min : 32 . 3 + / - 9 . 9 ml / 100 g / min ( P < 0 . 05 ) . 60 min : 30 + / - 7 . 5 ml / 100 g / min ( P < 0 . 05 ) ) . 