In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: METHODS : One hundred and fourteen children ( average age , 5 . 3 years ; range , twelve months to ten years and ten months ) who underwent closed reduction of an isolated fracture or dislocation in the emergency department at a level - I trauma center were prospectively evaluated .
### Output Text:
METHODS : One hundred and fourteen children ( average age , 5 . 3 years ; range , twelve months to ten years and ten months ) who underwent closed reduction of an isolated fracture or dislocation in the emergency department at a level - I trauma center were prospectively evaluated . 