In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Immunohistochemistry displayed significantly increased expressions of MMP - 2 , MMP - 9 , ADAM - 10 and ADAM - 17 ( all p < 0 . 01 ) in intima and media for CaCl ( 2 ) - treated segments .
### Output Text:
Immunohistochemistry displayed significantly increased expressions of MMP - 2 , MMP - 9 , ADAM - 10 and ADAM - 17 ( all p < 0 . 01 ) in intima and media for <span class="chemical">CaCl ( 2 )</span> - treated segments . 