In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: High - dose testosterone is associated with atherosclerosis in postmenopausal women .
### Output Text:
High - dose <span class="chemical">testosterone</span> is associated with atherosclerosis in postmenopausal women . 