In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Effects of an inhibitor of angiotensin converting enzyme ( Captopril ) on pulmonary and renal insufficiency due to intravascular coagulation in the rat .
### Output Text:
Effects of an inhibitor of <span class="chemical">angiotensin</span> converting enzyme ( <span class="chemical">Captopril</span> ) on pulmonary and renal insufficiency due to intravascular coagulation in the rat . 