In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The effect of PDTC on status epilepticus - associated cell loss in the hippocampus and piriform cortex was evaluated in the rat fractionated pilocarpine model .
### Output Text:
The effect of <span class="chemical">PDTC</span> on status epilepticus - associated cell loss in the hippocampus and piriform cortex was evaluated in the rat fractionated <span class="chemical">pilocarpine</span> model . 