In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: In almost half of these women severe atherosclerosis of the aorta was present ( n = 11 ) , while in women without hormone use severe atherosclerosis of the aorta was present in less than 20 % ( OR 3 . 1 ; 95 % CI , 1 . 1 - 8 . 5 , adjusted for age , years since menopause , smoking , and body mass index ) .
### Output Text:
In almost half of these women severe atherosclerosis of the aorta was present ( n = 11 ) , while in women without hormone use severe atherosclerosis of the aorta was present in less than 20 % ( OR 3 . 1 ; 95 % CI , 1 . 1 - 8 . 5 , adjusted for age , years since menopause , smoking , and body mass index ) . 