In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Patients who developed renal insufficiency had lower baseline body weight and higher baseline serum creatinine , required higher doses of loop diuretics , and were more likely to be treated with thiazide diuretics than controls .
### Output Text:
Patients who developed renal insufficiency had lower baseline body weight and higher baseline serum <span class="chemical">creatinine</span> , required higher doses of loop diuretics , and were more likely to be treated with <span class="chemical">thiazide</span> diuretics than controls . 