In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: In future , this form of therapy can offer a safe alternative in the treatment of cyclophosphamide - induced hemorrhagic cystitis .
### Output Text:
In future , this form of therapy can offer a safe alternative in the treatment of <span class="chemical">cyclophosphamide</span> - induced hemorrhagic cystitis . 