In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Pretreatment of TCR , at a dose of 0 . 5 mL / 100 g bodyweight per day , orally for 30 days , prevented the increase in lipid peroxidation and activity of marker enzymes observed in isoproterenol - induced rats ( 85 mg kg ( - 1 ) s . c . for 2 days at an interval of 24 h ) .
### Output Text:
Pretreatment of <span class="chemical">TCR</span> , at a dose of 0 . 5 mL / 100 g bodyweight per day , orally for 30 days , prevented the increase in lipid peroxidation and activity of marker enzymes observed in <span class="chemical">isoproterenol</span> - induced rats ( 85 mg kg ( - 1 ) s . c . for 2 days at an interval of 24 h ) . 