In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Baseline renal ACE positively correlated with the relative rise in proteinuria after adriamycin ( r = 0 . 62 , P < 0 . 01 ) , renal interstitial alpha - smooth muscle actin ( r = 0 . 49 , P < 0 . 05 ) , interstitial macrophage influx ( r = 0 . 56 , P < 0 . 05 ) , interstitial collagen III ( r = 0 . 53 , P < 0 . 05 ) , glomerular alpha - smooth muscle actin ( r = 0 . 74 , P < 0 . 01 ) and glomerular desmin ( r = 0 . 48 , P < 0 . 05 ) .
### Output Text:
Baseline renal ACE positively correlated with the relative rise in proteinuria after <span class="chemical">adriamycin</span> ( r = 0 . 62 , P < 0 . 01 ) , renal interstitial alpha - smooth muscle actin ( r = 0 . 49 , P < 0 . 05 ) , interstitial macrophage influx ( r = 0 . 56 , P < 0 . 05 ) , interstitial collagen III ( r = 0 . 53 , P < 0 . 05 ) , glomerular alpha - smooth muscle actin ( r = 0 . 74 , P < 0 . 01 ) and glomerular desmin ( r = 0 . 48 , P < 0 . 05 ) . 