In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: When the effects of IV drugs are inadequate in patients receiving CVVHDF , interference with adjacent catheters resulting in elimination of the drug by CVVHDF should be suspected .
### Output Text:
When the effects of IV drugs are inadequate in patients receiving CVVHDF , interference with adjacent catheters resulting in elimination of the drug by CVVHDF should be suspected . 