In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: CONCLUSION : Autophagic cardiomyocyte death plays an important role in the pathogenesis of heart failure in rats induced by adriamycin .
### Output Text:
CONCLUSION : Autophagic cardiomyocyte death plays an important role in the pathogenesis of heart failure in rats induced by <span class="chemical">adriamycin</span> . 