In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator - activated receptor - alpha target gene activation .
### Output Text:
Disruption of hepatic lipid homeostasis in mice after <span class="chemical">amiodarone</span> treatment is associated with peroxisome proliferator - activated receptor - alpha target gene activation . 