In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The cases of five depressed adolescents , 14 - 16 years of age , who developed mania during pharmacotherapy with fluoxetine , are reported here .
### Output Text:
The cases of five depressed adolescents , 14 - 16 years of age , who developed mania during pharmacotherapy with <span class="chemical">fluoxetine</span> , are reported here . 