In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: ACC - 9653 , the disodium phosphate ester of 3 - hydroxymethyl - 5 , 5 - diphenylhydantoin , is a prodrug of phenytoin with advantageous physicochemical properties .
### Output Text:
<span class="chemical">ACC - 9653</span> , the <span class="chemical">disodium phosphate ester</span> of <span class="chemical">3 - hydroxymethyl - 5 , 5 - diphenylhydantoin</span> , is a prodrug of <span class="chemical">phenytoin</span> with advantageous physicochemical properties . 