In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: CONCLUSION : According to Naranjo ' s algorithm the likelihood that our patient ' s agranulocytosis and thrombocytopenia occurred as a result of therapy with fluconazole is probable , with a total of six points .
### Output Text:
CONCLUSION : According to Naranjo ' s algorithm the likelihood that our patient ' s agranulocytosis and thrombocytopenia occurred as a result of therapy with <span class="chemical">fluconazole</span> is probable , with a total of six points . 