In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: However , no reports are available on the role of Ca ( 2 + ) in aconitine poisoning .
### Output Text:
However , no reports are available on the role of <span class="chemical">Ca</span> ( 2 + ) in <span class="chemical">aconitine</span> poisoning . 