In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The 200 - micrograms dose was able to totally abolish the deleterious renal effects of indomethacin , whereas the 800 - micrograms dose resulted in significant worsening of renal hemodynamics and sodium retention .
### Output Text:
The 200 - micrograms dose was able to totally abolish the deleterious renal effects of <span class="chemical">indomethacin</span> , whereas the 800 - micrograms dose resulted in significant worsening of renal hemodynamics and <span class="chemical">sodium</span> retention . 