In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The semisynthetic flavonoid monohydroxyethylrutoside ( monoHER ) showed cardioprotection against DOX - induced cardiotoxicity through its radical scavenging and iron chelating properties .
### Output Text:
The semisynthetic <span class="chemical">flavonoid</span> <span class="chemical">monohydroxyethylrutoside</span> ( <span class="chemical">monoHER</span> ) showed cardioprotection against <span class="chemical">DOX</span> - induced cardiotoxicity through its radical scavenging and <span class="chemical">iron</span> chelating properties . 