In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: RAD001 , an oral inhibitor of the mammalian target of rapamycin ( mTOR ) , has shown phase I efficacy in NSCLC .
### Output Text:
<span class="chemical">RAD001</span> , an oral inhibitor of the mammalian target of <span class="chemical">rapamycin</span> ( mTOR ) , has shown phase I efficacy in NSCLC . 