In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Fluoxetine improves the memory deficits caused by the chemotherapy agent 5 - fluorouracil .
### Output Text:
<span class="chemical">Fluoxetine</span> improves the memory deficits caused by the chemotherapy agent <span class="chemical">5 - fluorouracil</span> . 