In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Our data show that ablation of PKCa preserves AQP2 and UT - A1 protein expression and localization in lithium - induced NDI , and prevents the development of the severe polyuria associated with lithium therapy .
### Output Text:
Our data show that ablation of PKCa preserves AQP2 and UT - A1 protein expression and localization in <span class="chemical">lithium</span> - induced NDI , and prevents the development of the severe polyuria associated with <span class="chemical">lithium</span> therapy . 