In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The dose - dependent effect of misoprostol on indomethacin - induced renal dysfunction in well compensated cirrhosis .
### Output Text:
The dose - dependent effect of <span class="chemical">misoprostol</span> on <span class="chemical">indomethacin</span> - induced renal dysfunction in well compensated cirrhosis . 