In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: OBJECTIVE : To highlight the role of electroencephalogram ( EEG ) in the early detection and management of ifosfamide related encephalopathy .
### Output Text:
OBJECTIVE : To highlight the role of electroencephalogram ( EEG ) in the early detection and management of <span class="chemical">ifosfamide</span> related encephalopathy . 