In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Chloroacetaldehyde ( CAA ) is a metabolite of the alkylating agent ifosfamide ( IFO ) and putatively responsible for renal damage following anti - tumor therapy with IFO .
### Output Text:
<span class="chemical">Chloroacetaldehyde</span> ( <span class="chemical">CAA</span> ) is a metabolite of the alkylating agent <span class="chemical">ifosfamide</span> ( <span class="chemical">IFO</span> ) and putatively responsible for renal damage following anti - tumor therapy with <span class="chemical">IFO</span> . 