In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: CONCLUSION : There was no significant difference between isotonic sodium chloride , sodium bicarbonate and isotonic sodium chloride with diltiazem application in prevention of CIN .
### Output Text:
CONCLUSION : There was no significant difference between isotonic <span class="chemical">sodium chloride</span> , <span class="chemical">sodium bicarbonate</span> and isotonic <span class="chemical">sodium chloride</span> with <span class="chemical">diltiazem</span> application in prevention of CIN . 