In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: On this schedule , the animals ' hearts appeared normal after sacrifice and ICRF - 187 ( 50 mg / kg given i . p . 1 h before doxorubicin ) provided almost full protection .
### Output Text:
On this schedule , the animals ' hearts appeared normal after sacrifice and <span class="chemical">ICRF - 187</span> ( 50 mg / kg given i . p . 1 h before <span class="chemical">doxorubicin</span> ) provided almost full protection . 