In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: However , the results of the width of the GAP43 - ir band in the IML showed that CHX + Pilo and control animals had a significantly larger band ( p = 0 . 03 ) as compared with that in the Pilo group .
### Output Text:
However , the results of the width of the GAP43 - ir band in the IML showed that <span class="chemical">CHX</span> + <span class="chemical">Pilo</span> and control animals had a significantly larger band ( p = 0 . 03 ) as compared with that in the <span class="chemical">Pilo</span> group . 