In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: These data indicate that adult mouse atrial and ventricular cardiomyocytes do not synthesize DNA in response to isoproterenol - induced cardiac hypertrophy .
### Output Text:
These data indicate that adult mouse atrial and ventricular cardiomyocytes do not synthesize DNA in response to <span class="chemical">isoproterenol</span> - induced cardiac hypertrophy . 