In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: No statistical significance was found in the allele distribution of - 141Cins > del , TaqIB , rs6275 and TaqIA or in the estimated haplotypes ( constituted by TaqIB , rs6275 and TaqIA ) in linkage disequilibrium between the two groups .
### Output Text:
No statistical significance was found in the allele distribution of - 141Cins > del , TaqIB , rs6275 and TaqIA or in the estimated haplotypes ( constituted by TaqIB , rs6275 and TaqIA ) in linkage disequilibrium between the two groups . 