In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: In a 38 - year - old male patient suffering from a severe postzosteric trigeminal neuralgia , intravenous application of 10 mg biperiden lactate led to a long - lasting paradoxical reaction characterized by considerable bradycardia , dysarthria , and dysphagia .
### Output Text:
In a 38 - year - old male patient suffering from a severe postzosteric trigeminal neuralgia , intravenous application of 10 mg <span class="chemical">biperiden lactate</span> led to a long - lasting paradoxical reaction characterized by considerable bradycardia , dysarthria , and dysphagia . 