In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: It also induced an increase in the number of NADPH - d - positive cells in the dorsal part of the caudate and accumbens nuclei compared with haloperidol and in the pedunculopontine tegmental nucleus compared with saline .
### Output Text:
It also induced an increase in the number of <span class="chemical">NADPH</span> - d - positive cells in the dorsal part of the caudate and accumbens nuclei compared with <span class="chemical">haloperidol</span> and in the pedunculopontine tegmental nucleus compared with saline . 