In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: DESIGN : Dose response curves for nonsedating doses of morphine and CNSB002 given intraperitoneally alone and together in combinations were constructed for antihyperalgesic effect using paw withdrawal from noxious heat in two rat pain models : carrageenan - induced paw inflammation and streptozotocin ( STZ ) - induced diabetic neuropathy .
### Output Text:
DESIGN : Dose response curves for nonsedating doses of <span class="chemical">morphine</span> and <span class="chemical">CNSB002</span> given intraperitoneally alone and together in combinations were constructed for antihyperalgesic effect using paw withdrawal from noxious heat in two rat pain models : <span class="chemical">carrageenan</span> - induced paw inflammation and <span class="chemical">streptozotocin</span> ( <span class="chemical">STZ</span> ) - induced diabetic neuropathy . 