In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: After i . p . injection to rats , abecarnil and diazepam decreased in a time - dependent and dose - related ( 0 . 25 - 20 mg / kg i . p . ) manner [ 35S ] TBPS binding measured ex vivo in the cerebral cortex .
### Output Text:
After i . p . injection to rats , <span class="chemical">abecarnil</span> and <span class="chemical">diazepam</span> decreased in a time - dependent and dose - related ( 0 . 25 - 20 mg / kg i . p . ) manner <span class="chemical">[ 35S ] TBPS</span> binding measured ex vivo in the cerebral cortex . 