In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Effects of 17alpha - ethinylestradiol ( EE ) on the neutral and acidic biosynthetic pathways of bile salt ( BS ) synthesis were evaluated in rats with an intact enterohepatic circulation and in rats with long - term bile diversion to induce BS synthesis .
### Output Text:
Effects of <span class="chemical">17alpha - ethinylestradiol</span> ( <span class="chemical">EE</span> ) on the neutral and acidic biosynthetic pathways of <span class="chemical">bile salt</span> ( <span class="chemical">BS</span> ) synthesis were evaluated in rats with an intact enterohepatic circulation and in rats with long - term bile diversion to induce <span class="chemical">BS</span> synthesis . 