In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Bupivacaine 0 . 75 % with adrenaline was given followed by a 24 - hr continuous infusion of 0 . 25 % bupivacaine .
### Output Text:
<span class="chemical">Bupivacaine</span> 0 . 75 % with <span class="chemical">adrenaline</span> was given followed by a 24 - hr continuous infusion of 0 . 25 % <span class="chemical">bupivacaine</span> . 