In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: CONCLUSION : Lovastatin is highly effective and generally well tolerated as therapy for primary hypercholesterolemia in women .
### Output Text:
CONCLUSION : <span class="chemical">Lovastatin</span> is highly effective and generally well tolerated as therapy for primary hypercholesterolemia in women . 