In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: The mean change in the creatinine concentration from day 0 to day 7 was 0 . 07 mg per deciliter in the iodixanol group and 0 . 24 mg per deciliter in the iohexol group ( P = 0 . 003 ; value in the iodixanol group minus the value in the iohexol group , - 0 . 17 mg per deciliter [ 95 percent confidence interval , - 0 . 34 to - 0 . 07 ] ) .
### Output Text:
The mean change in the <span class="chemical">creatinine</span> concentration from day 0 to day 7 was 0 . 07 mg per deciliter in the <span class="chemical">iodixanol</span> group and 0 . 24 mg per deciliter in the <span class="chemical">iohexol</span> group ( P = 0 . 003 ; value in the <span class="chemical">iodixanol</span> group minus the value in the <span class="chemical">iohexol</span> group , - 0 . 17 mg per deciliter [ 95 percent confidence interval , - 0 . 34 to - 0 . 07 ] ) . 