In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Ventricular fibrillation occurred significantly more often with Renografin , suggesting that chelating agents contribute to toxicity in coronary angiography .
### Output Text:
Ventricular fibrillation occurred significantly more often with <span class="chemical">Renografin</span> , suggesting that chelating agents contribute to toxicity in coronary angiography . 