In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Hypotension , bradycardia , and asystole after high - dose intravenous methylprednisolone in a monitored patient .
### Output Text:
Hypotension , bradycardia , and asystole after high - dose intravenous <span class="chemical">methylprednisolone</span> in a monitored patient . 