In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Structural and functional impairment of mitochondria in adriamycin - induced cardiomyopathy in mice : suppression of cytochrome c oxidase II gene expression .
### Output Text:
Structural and functional impairment of mitochondria in <span class="chemical">adriamycin</span> - induced cardiomyopathy in mice : suppression of cytochrome c oxidase II gene expression . 