In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Both presented in the emergency room with profound coma , hypotension , severe hyperglycemia , and acidosis .
### Output Text:
Both presented in the emergency room with profound coma , hypotension , severe hyperglycemia , and acidosis . 