In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: 8 of the 10 monkeys developed congestive heart failure at an average cumulative adriamycin dose ( 310 mg / m2 ) well below that considered the safe upper limit ( 550 mg / m2 ) in man .
### Output Text:
8 of the 10 monkeys developed congestive heart failure at an average cumulative <span class="chemical">adriamycin</span> dose ( 310 mg / m2 ) well below that considered the safe upper limit ( 550 mg / m2 ) in man . 