In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: After IT morphine , the cerebrospinal fluid ( CSF ) glutamate concentration was increased in group M relative to both baseline and group C ( P < 0 . 05 ) .
### Output Text:
After IT <span class="chemical">morphine</span> , the cerebrospinal fluid ( CSF ) <span class="chemical">glutamate</span> concentration was increased in group M relative to both baseline and group C ( P < 0 . 05 ) . 