In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: In a more complex task commonly used to evaluate major akinetic symptoms of PD patients , 5 mg / kg AMN082 reverses the increased reaction time to respond to a cue of bilateral 6 - OHDA - lesioned rats .
### Output Text:
In a more complex task commonly used to evaluate major akinetic symptoms of PD patients , 5 mg / kg <span class="chemical">AMN082</span> reverses the increased reaction time to respond to a cue of bilateral <span class="chemical">6 - OHDA</span> - lesioned rats . 