In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Coenzyme Q10 significantly compensated deficits in the antioxidant defense mechanisms ( reduced glutathione level and superoxide dismutase activity ) , suppressed lipid peroxidation , decreased the elevations of tumor necrosis factor - alpha , nitric oxide and platinum ion concentration , and attenuated the reductions of selenium and zinc ions in renal tissue resulted from cisplatin administration .
### Output Text:
<span class="chemical">Coenzyme Q10</span> significantly compensated deficits in the antioxidant defense mechanisms ( <span class="chemical">reduced glutathione</span> level and <span class="chemical">superoxide</span> dismutase activity ) , suppressed lipid peroxidation , decreased the elevations of tumor necrosis factor - alpha , <span class="chemical">nitric oxide</span> and <span class="chemical">platinum</span> ion concentration , and attenuated the reductions of <span class="chemical">selenium</span> and <span class="chemical">zinc</span> ions in renal tissue resulted from <span class="chemical">cisplatin</span> administration . 