In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Effect of methanolic extract of Hibiscus rosa sinensis ( 100 - 300 mg / kg ) was studied on reserpine - induced orofacial dyskinesia and neurochemical alterations .
### Output Text:
Effect of methanolic extract of <span class="chemical">Hibiscus rosa sinensis</span> ( 100 - 300 mg / kg ) was studied on <span class="chemical">reserpine</span> - induced orofacial dyskinesia and neurochemical alterations . 