In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: DESIGN : Fluoxetine , a serotonin reuptake inhibitor , was given to Wistar Albino rats for 98 days to produce hyperprolactinemia .
### Output Text:
DESIGN : <span class="chemical">Fluoxetine</span> , a <span class="chemical">serotonin</span> reuptake inhibitor , was given to Wistar Albino rats for 98 days to produce hyperprolactinemia . 