In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Immunohistochemical analysis revealed that coenzyme Q10 significantly decreased the cisplatin - induced overexpression of inducible nitric oxide synthase , nuclear factor - kappaB , caspase - 3 and p53 in renal tissue .
### Output Text:
Immunohistochemical analysis revealed that <span class="chemical">coenzyme Q10</span> significantly decreased the <span class="chemical">cisplatin</span> - induced overexpression of inducible <span class="chemical">nitric oxide</span> synthase , nuclear factor - kappaB , caspase - 3 and p53 in renal tissue . 