In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: In summary , suprofen causes acute declines in renal function , most likely by directly altering the intrarenal distribution of uric acid .
### Output Text:
In summary , <span class="chemical">suprofen</span> causes acute declines in renal function , most likely by directly altering the intrarenal distribution of <span class="chemical">uric acid</span> . 