In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Cyclophilin A and FK506 - binding protein , the main intracytoplasmic receptors for CsA and FK506 , respectively , were each detected in renal tissue extract .
### Output Text:
Cyclophilin A and <span class="chemical">FK506</span> - binding protein , the main intracytoplasmic receptors for <span class="chemical">CsA</span> and <span class="chemical">FK506</span> , respectively , were each detected in renal tissue extract . 