In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Cyclosporin A ( CsA ; 50 mg / kg ) and Fujimycine ( FK506 ; 5 mg / kg ) , but not the related macrolide immunosuppressant rapamycin ( 5 mg / kg ) , caused a reduction of glomerular filtration rate , degenerative changes of proximal tubular epithelium , and hypertrophy of the juxtaglomerular apparatus in male Wistar rats when given for 10 days .
### Output Text:
<span class="chemical">Cyclosporin A</span> ( <span class="chemical">CsA</span> ; 50 mg / kg ) and <span class="chemical">Fujimycine</span> ( <span class="chemical">FK506</span> ; 5 mg / kg ) , but not the related <span class="chemical">macrolide</span> immunosuppressant <span class="chemical">rapamycin</span> ( 5 mg / kg ) , caused a reduction of glomerular filtration rate , degenerative changes of proximal tubular epithelium , and hypertrophy of the juxtaglomerular apparatus in male Wistar rats when given for 10 days . 