In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: For human glioblastoma recurrences , the feasibility , safety , and short - term effects of a surgical intracavitary application of paclitaxel and carboplatin encapsulated by liquid crystalline cubic phases are examined in a pilot study .
### Output Text:
For human glioblastoma recurrences , the feasibility , safety , and short - term effects of a surgical intracavitary application of <span class="chemical">paclitaxel</span> and <span class="chemical">carboplatin</span> encapsulated by liquid crystalline cubic phases are examined in a pilot study . 