In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: We conclude that the combination of paclitaxel 185 mg / m2 administered as a 3 - hour infusion followed immediately by a 1 - hour infusion of carboplatin at an AUC of 6 can be administered safely in a 21 - day schedule in the outpatient setting .
### Output Text:
We conclude that the combination of <span class="chemical">paclitaxel</span> 185 mg / m2 administered as a 3 - hour infusion followed immediately by a 1 - hour infusion of <span class="chemical">carboplatin</span> at an AUC of 6 can be administered safely in a 21 - day schedule in the outpatient setting . 