In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Loss of glutamate decarboxylase mRNA - containing neurons in the rat dentate gyrus following pilocarpine - induced seizures .
### Output Text:
Loss of <span class="chemical">glutamate</span> decarboxylase mRNA - containing neurons in the rat dentate gyrus following <span class="chemical">pilocarpine</span> - induced seizures . 