In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: Effect of increasing intraperitoneal infusion rates on bupropion hydrochloride - induced seizures in mice .
### Output Text:
Effect of increasing intraperitoneal infusion rates on <span class="chemical">bupropion hydrochloride</span> - induced seizures in mice . 