In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: It consists of microangiopathic hemolytic anemia , thrombocytopenia and progressive renal failure associated with mitomycin C treatment and affects about 10 % of patients treated with this agent .
### Output Text:
It consists of microangiopathic hemolytic anemia , thrombocytopenia and progressive renal failure associated with <span class="chemical">mitomycin C</span> treatment and affects about 10 % of patients treated with this agent . 