In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. 
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.

### Input Text: We performed DSE on 51 patients with coronary spastic angina but without significant fixed coronary artery stenosis .
### Output Text:
We performed DSE on 51 patients with coronary spastic angina but without significant fixed coronary artery stenosis . 