We stayed 2 nights in a Balcony Suite, which was light-filled, spacious, and very functional. I chose it because of the location--it was near the Harry Potter event at the Science Center (stop laughing). The restaurant downstairs is pricey, but quite good with many inventive dishes. Road noise was a little loud, but generally pretty mild for a city hotel. If you are planning to spend most of your time by the water/Pike Place/etc., I'd probably recommended getting a hotel down there given the distance, but Pan Pacific is near the Science Center, Space Needle, and that complex. We used valet parking, because the parking lot out front is shared by many businesses--however, I later saw that they had a self-park entry to the garage off the street. You can walk out to several businesses, including yoga, food places, spa, etc.
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