We first stayed at the Serrano in January of 2003. Having decided to visit San Francisco I started doing some google searches and chose it because it looked quite nice. Let me tell you - after a 18 hour journey the place seemed like heaven. A very comfortable bed and a well appointed bathroom were more than welcome sights. We enjoyed our stay so much we came back in 2004 for another two week stay. I found a fantastic rate by regularly checking their website - which was just as well as my wife had let it be known that "we can stay anywhere you like as long as it's the Serrano".
I had been a bit worried that it might not be as good as we remembered - my concerns were groundless. The staff were as friendly, the room was as nice, the atmosphere was as good as we remembered. The staff were attentive without being intrusive and the rooms were kept very clean. Just make sure you ask for a high floor - you can get some good views if you get the right room.
Special mention goes to Jose in the Ponzu restaurant (a constant source of good advice on where to eat) and to Chet the doorman (who was the only person in the whole city who didn't think we were Irish).
Finally, I can think of no better recommendation to give it than that we are already planning our next two week stay there in 2005.
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