If you are not a spoiled hoity-toity, the Castle Inn will serve you very well as a base for your SF trip. It is not fancy, but it is very clean and the price is right. The neighborhood is very safe and offers good food, bars, Walgreens, and coffee shops. Buy a MUNI pass-- you can pick up a bus or cable car going almost anywhere in SF from a stop near the hotel. Some of my family's best memories are from riding the bus; every ride we took offered great people-watching and yet it is completely safe.
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