text:
This is a story of collaboration and a testament to what can be achieved through partnerships and shared values. These values have created the foundation on which we have been able to foster innovation, creativity, sustainability, artistry and city-building.
Our partnership with Allied and BIG began with TELUS Sky in Calgary. Today, we are building upon the relationships we have formed to expand our work and bring a new project to Toronto, with even greater ambition.
Westbank is a practice dedicated to the creation of beauty, in all forms and in the broadest definition. As we have grown the category of a developer has become too narrow to contain the essence of our practice. We are not motivated by the same things as a developer, our values are different: we invite collaborations with cultural pioneers, showcasing their work and allowing it to inform and influence our projects. We strive to develop relationships with creatives so that we function as patrons of their art, rather than as consumers of artistic services. We embrace our eclectic nature, broadening our interests and seeking out willing collaborators in art, culture, music, fashion, technology, sustainability, and architecture, while taking on projects at every scale, from the micro to the macro level. We are and have always been a practice seeking to make meaningful contributions to the cities in which we work and we see the creation of beauty as the means to this end. Through these and other endeavors, we have come to realize that too often, beauty is mistaken as a luxury, an option or an accessory, when we have never seen it as anything less than essential. Recognizing this, we have taken it upon ourselves to fight for it; to create it, to foster it and to celebrate it. In committing our efforts fully to this end, we have evolved beyond the definition of a real estate development firm, to become a culture company.
Allied operates first and foremost on the principle that real estate is a profoundly human business. Our properties are run by people for people, and we've built our portfolio to better serve the people who use our buildings. In 2003, we went public for the express purpose of consolidating high- quality workspace, enabling us to become a leading owner, manager and developer of urban office properties in Canada. Our commitment to distinctive urban workspace is founded on a clear value proposition: well- designed, centrally located, distinctive and cost-effective workspace that adds value, socially, culturally and economically, for our users and for the communities and the cities in which our buildings operate. We believe that each building represents an investment in the community and recognize that the strength of a neighbourhood, as well as the performance of buildings within it, are inextricably linked. Allied is also a product of its history and its business environment. Increasingly, the single most important element of our business environment is urban intensification. Canadians are living and working downtown in greater numbers than ever before. The future of Allied is in the future of urban workspace. It involves the continued consolidation and mixed-use intensification of distinctive urban office properties, sensitivity to design and collaboration, each of which are integral to our success and also add value – economically, socially and culturally. We are committed to creating urban office environments that enrich experience and support the success of our tenants, while contributing vitality to the urban fabric of our cities.
BIG is a Copenhagen, New York and London based group of architects, designers, urbanists, landscape professionals, interior and product designers, researchers and inventors. The office is currently involved in a large number of projects throughout Europe, North America, Asia and the Middle East. BIG's architecture emerges out of a careful analysis of how contemporary life constantly evolves and changes. Not least due to the influence from multicultural exchange, global economical flows and communication technologies that all together require new ways of architectural and urban organization. BIG believes that in order to deal with today's challenges, architecture can profitably move into a field that has been largely unexplored. A pragmatic utopian architecture that steers clear of the petrifying pragmatism of boring boxes and the naïve utopian ideas of digital formalism. Like a form of programmatic alchemy, we create architecture by mixing conventional ingredients such as living, leisure, working, parking and shopping. By hitting the fertile overlap between pragmatic and utopia, we architects once again find the freedom to change the surface of our planet, to better fit contemporary life forms.
Bjarke Ingels founded BIG Bjarke Ingels Group in 2005 after co-founding PLOT Architects in 2001 and working at OMA in Rotterdam. Bjarke defines architecture as the art and science of making sure our cities and buildings fit with the way we want to live our lives. Through careful analysis of various parameters from local culture and climate, ever changing patters of contemporary life, to the ebbs and flows of the global economy, Bjarke believes in the idea of information-driven-design as the driving force for his design process. Named one of the 100 Most Influential People in the World by TIME Magazine in 2016, Bjarke has designed and completed award-winning buildings globally.
In 2011, Wall Street Journal named Bjarke the Innovator of the Year; he received the Danish Crown Prince's Culture Prize in 2011; the Golden Lion at the Venice Biennale in 2004; and the ULI Award for Excellence in 2009. Alongside his architectural practice, Bjarke has taught at Harvard University, Yale University, Columbia University, and Rice University and is an honorary professor at the Royal Academy of Arts, School of Architecture in Copenhagen. He is a frequent public speaker and continues to hold lectures in venues such as TED, WIRED, AMCHAM, 10 Downing Street, the World Economic Forum and many more. In 2018, Bjarke was named Chief Architectural Advisor by WeWork to advise and develop the firm's design vision and language for buildings, campuses and neighbourhoods globally.
Address: King West
Zip/Postal Code: M5V 1K4
Neighborhood: Down Town
Price: From $1,600/Per Sq.Ft.
Property Type: Apartment, Condo, Single Family Home
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Therapeutic Aesthetics (0.11 km)
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Pups of Anarchy (0.22 km)
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Toronto LX Limo (0.13 km)
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Hello, I am interested in [King Toronto Condo]
King Toronto Condo - King Street West, Toronto,


Discussion in 'News and Announcements' started by Fukaziroh_, Sep 2, 2017.
After quite a while we are happy to announce our latest big SG:RL update including lots of new features improving your overall game experience aswell as more content being shipped!
Attachments are being brought back remastered to SG:RL!
You can customize your gun how you like it with the proper attachments you find in chests.
Each weapon has certain attachment slots so some attachments aren't compatible with others to prevent over powered guns from being made.
Hold a gun and write /att to add current attachments to your gun and /det to remove attachments of your guns.
Some attachments such as an Extended Magazine can exist in various variants one for Sniper Rifles, one for Assault Rifles and SMGs ect. to balance out attachments across the board.
We've brought back the old ammo system from SG:RL where you need the actual caliber in order to reload the gun. Example taken here from these weapons.
ARX-200 a designated marksman rifle with high travel speed and fast reload speed with a draw back of having high recoil compared to the other DMRs.
PDW-R a sub machine gun chambered in 5.56x45mm NATO, delievering medium firepower with good range and accuracy including the ability to attach both assault rifle and smg attachments on this weapon with it's drawback of having long reload times and high recoil.
Galil ACE 52 CQB an assault rifle as the replacement of the AN-94, fires 7.62x51mm NATO rounds at low muzzle velocity, the recoil remains similar to the other 7.62mm rifles while it's weight and accuracy is decreased.
They have returned! You will be able to choose kits now from the lobby! Hogwild, Piglet and Boar get their own exclusive kits. However Kits will now only give you an advantage at the start of the game, we removed the Kit/Pay 2 Win factor of them by removing any special items and strong guns.
The whole stats system ingame has been reworked now showing the actual stats of the gun aswell as showing your the attachments you've put on your current weapon.
On the current system there is an invisible delay between switching your weapons so you cannot spam fire weapons without being punished for doing so. Now all weapons excluding the Launchers and the Special weapons now have a draw sound matching the switch delay's timer similar to Counter Strike: Global Offensive's slide pulling every switch but instead of with animations it's done purely with sounds replicating pulling the bolt or pumping the gun.
The timer until you start to die out in deathmatch has been increased to 5 Minutes from 1. This encourages players to play smarter with that amount time instead of trying to get the first shots and then hide until the enemy dies by being wounded from before.
now you may only carry 2 Heavy weapons (Under heavy weapons: Assault Rifles, SMGs, DMRs, LMGs, Launchers, Sniper Rifles, Shotguns count) and a Light weapon (Pistol) if you carry more than the limit in your hotbar your access of shooting will be restricted until your hotbar meets the limits correctly.
Guns can be still stored in your inventory without any restriction, just not your hotbar.
Now you will be able to find consumeable gadgets such as M67 Frags, M18 Smokes and M84 Flashbangs in the chests available for your use in the battlefield!
I wish I could push out this much content.
One of the fastest things I have ever clicked on in my life. My only question is revolving around healing. Can you find healing in chests? So if you are about to be cleaned up / go into deathmatch just fresh out of a health draining fight, you won't get cleaned by other players?
Currently not. Healing will be added in an later update which will be decided by vote which will follow later this day. However some kits such as the Medic and Navy Seal offer healing potions that heal you up quite a bit.
Just stay tuned for the vote.
Ok thank you. Will definitely be voting pro-healing.
Can I get a tactical hazmat suit please?


text:
Mike Huckabee calls Colin Kaepernick a 'Typhoid Mary' in Twitter attack on ex-49ers QB
By Andy Clayton
Colin Kaepernick takes action after failing to land an NFL gig by filing a grievance against the league charging collusion. (Marcio Jose Sanchez/AP)
Colin Kaepernick has been called a lot of things, but leave it to Mike Huckabee to take the name-calling to a new level.
The former Arkansas governor took to Twitter Tuesday morning to call the ex-49ers quarterback a "Typhoid Mary."
Kaepernick, who has been exiled from the league a season after he began kneeling during the national anthem, filed a grievance Sunday against the NFL claiming the league's owners have banded together to keep him out.
"Why won't a team hire Colin Kaepernick?" Huckabee tweeted. "Same reason a hospital wouldn't hire Typhoid Mary-when you kill off your customers U go out of biz!"
Why won't a team hire Colin Kaepernick? Same reason a hospital wouldn't hire Typhoid Mary-when you kill off your customers U go out of biz!
— Gov. Mike Huckabee (@GovMikeHuckabee) October 17, 2017
Kaepernick took a knee during the pre-game playing of "The Star-Spangled Banner" last season in an effort to raise awareness of police brutality against minorities and social injustice. He opted out of his contract with the 49ers in the offseason and has yet to get an offer from another team.
Huckabee, who has twice run for president and is an active supporter of President Trump, denied politics is keeping Kaepernick out of the NFL.
"Kaepernick whines he's not hired because of his politics," Huckabee wrote. "Not true! It's the Russians, Comey, and Trump! Oh wait-that excuse already taken."
The anthem protests had slowed this season - with just a handful of NFL players continuing to kneel or raise a fist - until Trump attacked the league last month in a speech in Alabama.
Players kneel during the national anthem following Trump's comments
Trump called on NFL owners to fire any player who protests during the national anthem.
"Wouldn't you love to see one of these NFL owners, when somebody disrespects our flag, say, 'Get that son of a b---- off the field right now," Trump said. "Out, you're fired!'"
Trump's attack reignited the protest movement and united the players like never before.
How to deal with anthem protests is a key topic at the NFL owners meetings taking place this week in lower Manhattan. Although several players will be involved in the NFL's discussions this week, Kaepernick was not invited to attend.
Former Arkansas Gov. Mike Huckabee takes to Twitter to bash for former 49ers quarterback. (Richard Drew/AP)
Mary Mallon - aka Typhoid Mary - was believed to have infected more than 50 people with Typhoid in the early 1900s in New York in her role as a cook. She was eventually forced into exile and lived in forced isolation for the last 20-plus years of her life.
Today people use "Typhoid Mary" as a colloquial term to describe someone who spreads disease.
Huckabee's daughter - Sarah Huckabee Sanders - is part of Team Trump. She currently serves as the White House press secretary.

redpajama_set_name: RedPajamaCommonCrawl


Show up. Lift heavy things. Go home.
Solid plan. The problem is, this narrow set of goals completely ignores one of the most important methods of mobility development: SMR, or self-myofascial release. Most people are at least minimally familiar with the concept of SMR, even if they don't know it, but fewer have adopted it as a standing task on their workout checklists.
SMR is the practice of manually attempting to release or eliminate muscular adhesions and scar tissue, usually by way of foam rollers, lacrosse balls or deep-tissue massage. It's the most tedious and painful investment you can make in the durability of your chassis, health of your connective tissue and the longevity of your training life.
Research published in a 2015 issue of the International Journal of Sports Physical Therapy examined 14 different peer-reviewed studies on the effectiveness of SMR. The goal was to determine whether SMR could a) improve joint range of motion (ROM) without affecting muscle performance, b) enhance post-exercise muscle recovery and reduce delayed onset muscle soreness (DOMS), and/or c) negatively impact muscle performance.
Researchers found that subjects who used a foam roller for 30 to 60 seconds before and after exercise may offer short-term benefits on hip, back, knee and ankle mobility. But how? Quoting the study, "It has been postulated that ROM changes may be due to the altered viscoelastic and thixotropic property (gel-like) of the fascia, increases in intramuscular temperate and blood flow due to friction of the foam roll, alterations in muscle-spindle length or stretch perception, and the foam roller mechanically breaking down scar tissue and remobilizing fascia back to a gel-like state." Put simply, it's keeping your myofascial complex healthy and making it more efficient at doing what you want it to do.
It's as crippling as it is rewarding, but foam rolling may be one of the best ways to combat DOMS and speed recovery. Researchers found that a 10- to 20-minute tussle with the ol' foam roller postworkout helped reduce perceived pain in subjects while reducing expected drops in performance. Why? It is thought SMR helps to facilitate blood lactate removal while reducing swelling and bathing your muscles in recovery-inducing oxygenated blood.
Research has steered us away from the old practice of cold-stretching muscles or spending too much time static stretching between sets. This is because placing the muscle under stretch may acutely weaken the muscle. But foam rolling — which helps increase muscle pliability and blood flow — shows no such risk of performance issues. Subjects who foam-rolled for just 30 seconds preworkout (after a dynamic, lower-body warm-up) demonstrated a longer time-to-fatigue than those who did not roll. It should be noted that the inclusion of the SMR protocol did not necessarily enhance performance but no negative effects were shown.
Note: For some upper-body SMR interventions, a lacrosse ball against a wall while standing is a strong, viable alternative to floor work.
If you hit a tender spot, focus additional attention on that area because the local pain could signal an existing or developing problem with your fascia. Bottom line is that if you don't already own a foam roller, it may be time to invest in one. Try the TriggerPoint Core Foam Roller, available at vitaminshoppe.com for $29.99.


As motorhome tourists travel through Europe there is an abundance of what are referred to in the English language as 'Aires'.
In the same way as 'a la carte' which means 'on the menu' and 'nom de plume' which means 'pen name' have been adopted into the English Language so has 'Aire de Stationnement' which means 'parking area' the full title however has been shortened to 'Aire' for convenience.
Throughout Europe if local Bye-laws are checked it will be seen that camping, wild or otherwise, is often forbidden in an area.
Tourists using motorhomes are expressly not permitted to engage in any activity which has been deemed to be camping, other than in approved camp sites or caravan and camping parks as they are commonly referred to.
It is the effective use of this type of Bye-law which ensures 'Aires' remain simple parking areas and enables local law enforcement to ensure such areas do not degenerate into unofficial encampments with undesirable consequences for the local environment.
Local authorities have appeared not to have understood what their counterparts in Europe have known for quite a while, that camping as an activity can be defined and if environmentally or socially inappropriate in an area, like any other such activity, it can be controlled through its prohibition by an appropriate Bye-law.
In the absense of such foresight Local Authorities in Ireland seek to ban outright the placement of all'temporary dwellings' in certain areas. Motorhomes, falling within the definition of a 'temproary dwelling' are thus restricted in where they may park. The effect of this blunderbuss approach is that Ireland is percieved as being unfriendly to motorhome tourists.
The creation of a sufficient number of such overnight Motorhome Parking places will enable motorhome tourists to tour at their leisure and enjoy the beauty of our country, be it our rugged Atlantic coastline, excellent 'Blue Flag' beaches, inland lakes and mountains or historic cities and towns .
Motorcaravanning Ireland does not support camping. wild or otherwise, apart from on private land with the owners permission or approved caravan and camping parks.
Parking! Camping! so What's the Difference?
Throughout Europe local authorities/councils have in place anti-camping Bye-laws while at the same time providing parking facilities for motorhomes.
It occupies no greater a footprint than when it is being driven.


While a lot of people go for the different and the mobile phones, the fact remains that there is no other company that can actually come in comparison with Nokia. Nokia happens to be one of the best-known mobile companies that would be able to find in the market, and it has actually been able to provide you with the necessary amount of relief, as well as cutting-edge technology has also been introduced in order to help a person to actually bring about the necessary amount of changes to that aspect. Taking such things into contention, it can actually be a very good idea on your behalf to ensure that you would be able to go for Nokia mobile phones.
Understandably, there are a lot of people that prefer to undertake the use of the different kinds of mobile phones of various companies, but the fact remains that the battery backup of the Nokia phones is unsurpassable by any other mobile company. This way, you would be able to bring about the necessary amount of changes to your life by undertaking the use of a mobile phone.


text:
Cosmasterias felipes är en sjöstjärneart som först beskrevs av Percy Sladen 1889.  Cosmasterias felipes ingår i släktet Cosmasterias och familjen trollsjöstjärnor. Inga underarter finns listade i Catalogue of Life.

Källor

Trollsjöstjärnor
felipes

redpajama_set_name: RedPajamaWikipedia


text:
The 2010-2015 coalition and criminal justice: Continuities and contradictions
Fox, C and Bannister, J and Miszczak, P (2016) The 2010-2015 coalition and criminal justice: Continuities and contradictions. Safer Communities, 15. ISSN 1757-8043
© Emerald Group Publishing Limited.Purpose - The criminal justice system (CJS) in England and Wales went through extensive reform under the Coalition Government of 2010-2015. In this paper, and through the lens of policing, prisons and probation, the authors set out to identify the direction and qualities of these reforms. The paper aims to discuss these issues. Design/methodology/approach - The authors review key policy documents produced by the Coalition Government as well as relevant critiques. The authors concentrate on policing, prisons and probation on the basis that interrogation of these major aspects of the CJS should enable the principles underpinning the Coalition's approach to the CJS to be discerned. Findings - The authors identify key themes, and their contradictions, that emerged in the Coalition Government's approach to the CJS, these being: devolution and centralism; marketization with a growing emphasis on payment by results; politicisation and de-politicisation; and, evidence-based policy. Research limitations/implications - This is a review of recent government policy and as such some of the implications and outcomes resulting from that policy are not yet clear. Practical implications - This paper will be of particular use to those working in or studying UK criminal justice policy. Given that themajority partner in the Coalition went on to form the current government policy trends from the recent Coalition are likely to have some relevance to current government policy making in the CJS. Originality/value - To date there have only been limited attempts to identify key policy trends emerging from the Coalition Government.
Emerald Group Publishing Limited
This is an Author Final Copy of a paper accepted for publication in Safer Communities, published by and copyright Emerald Group Publishing Limited.
Faculties > Arts and Humanities
Research Centres > Research Centre for Applied Social Sciences
https://doi.org/10.1108/SC-11-2015-0039


text:
Turks get another new currency
ISTANBUL – For the second time in four years the Turks have to get used to new money: on the first of January, the 'yeni Türk lirasi' (new Turkish lira), which was introduced at 1 January 2005, will be a thing of the past. The word 'yeni' will be removed and the notes will have a new look.
The new Turkish lira was introduced four years ago as part of economic reforms in which the currency was also revalued: 1 million Turkish lira became 1 new Turkish lira. The evaluation period of the new currency is now over and the currency gets back its original name.
What is different this time is that the banknotes show not only modern Turkey's founding father Atatürk (smiling this time), but also six other historically important Turks. One of them is a woman, which has aroused some debate: strong secularists criticised the choice of a Muslim-feminist writer and would have preferred a woman of Atatürk's time to appear on the fifty lira note.
Tags: ANP
https://frederikegeerdink.com/wp-content/uploads/2020/07/Frederike-Geerdink-1-300x114.jpg 0 0 fgeerdink https://frederikegeerdink.com/wp-content/uploads/2020/07/Frederike-Geerdink-1-300x114.jpg fgeerdink2008-12-30 10:38:042016-01-05 15:31:39Turks get another new currency
Third term for 'Islamist' Erdoğan
Turkey put aid on hold on purpose
Ankara wants monument Algerian war of independence
Turkish minister says Wilders is 'not relevant'
Al Qaeda suspects arrested in Turkey
Turkish president visits Kurdish area
Dutch Turks involved in Turkish referendum
Massive commemoration of murdered journalist
Pure silver 6785824


text:
国产CHINESE在线男同
Antibiotic resistance. The things we do to make it worse. And anything else I find interesting.
Showing posts with label NDM-1. Show all posts
Gone. (Again.) And it's really exciting. (And some NDM-1, too.)
Constant readers, cast your minds back to early summer, when SUPERBUG briefly bugged out of here to Scienceblogs. Scienceblogs was a great community, but not quite the right fit, and so I ended up happily back here, doing my own thing, and you very kindly followed me. And it's been an exciting few months back here, with lots of news on NDM-1 (look here for the archive), and flu and C. diff and HAIs.
And now, some real news. SUPERBUG is moving again. And this is going to be great.
I'm thrilled to be one of seven launch bloggers in a new network set up at Wired.com: Wired Science. It's an amazing, diverse group, high-performance and hyper-cool: Frontal Cortex, Neuron Culture, Laelaps, Dot Physics, Clastic Detritus, Genetic Future, and me. I'm beyond flattered to be among them.
Our launch announcement is here. My new page is here. (The complete addy, which may change in a few weeks after a tweak, but keep it for now:
/wiredscience/superbug/)
My inaugural post is the latest news, from the ICAAC meeting, on NDM-1.
We're having some issues with the archives, so I'll be leaving this site up as a resource. But I'd love to see you there as well as here. Please come check us out. And thank you, so much, for your loyalty, interest and attention over these years.
Posted by Maryn McKenna at 12:15 PM No comments:
Labels: NDM-1, personal
NDM-1: The World Health Organization warns governments
The World Health Organization released a statement this afternoon, prompted by news of the NDM-1 multi-resistance gene. It's worth taking a look: The agency recommends that countries around the world pay serious attention to the emergence of this resistance factor.
WHO calls for broad action within countries, from hospital infection-control and antibiotic-stewardship programs, to increased surveillance for the emergence of resistance, to legislative control of over-the-counter sales. Those sound like (and are) minimal and rational suggestions — but they have the potential to be quite controversial in some countries, from India where OTC antibiotic purchases are a major economic sector, to the US where best practices for hospital control of resistant organisms continue to be, umm, vociferously debated.
The WHO says:
Those called upon to be alert to the problem of antimicrobial resistance and take appropriate action include consumers, prescribers and dispensers, veterinarians, managers of hospitals and diagnostic laboratories, patients and visitors to healthcare facilities, as well as national governments, the pharmaceutical industry, professional societies, and international agencies.
WHO strongly recommends that governments focus control and prevention efforts in four main areas:
surveillance for antimicrobial resistance;
rational antibiotic use, including education of healthcare workers and the public in the appropriate use of antibiotics;
introducing or enforcing legislation related to stopping the selling of antibiotics without prescription; and
strict adherence to infection prevention and control measures, including the use of hand-washing measures, particularly in healthcare facilities.
The WHO has been working on antibiotic resistance for a while now, though the effort seems to be continually obscured by urgent news of outbreaks such as SARS, H5N1, H1N1 and so on. Here's their short fact sheet, detailed program page, and Global Strategy for Containment of Antibiotic Resistance (sadly 9 years old, so it predates the emergence of community MRSA, not to mention NDM-1).
Posted by Maryn McKenna at 2:16 PM No comments:
Labels: India, NDM-1, stewardship, surveillance, WHO
NDM-1: The early warnings
Sorry to drop out of sight, constant readers; a little medical emergency at Casa Superbug, but all better now. There are some new developments regarding the novel resistance factor NDM-1, which renders Gram-negative bacteria resistant to almost all antibiotics:
Germany has announced its first identifications — plural, apparently. (Bloomberg News)
Vietnam says it has also recorded its presence. (Thanh Nien Daily, h/t H5N1)
And France says that it will begin testing for the gene's presence in bacteria carried by patients being admitted to hospitals, in hopes of keeping the plasmid from transferring to other bacterial species and creating a wider resistance problem. (Agence France Presse) This is a reasonable fear; it is analogous to the process by which MRSA became vancomycin-resistant (VRSA), by acquiring the gene for vancomycin resistance from VRE, vancomycin-resistant Enterococcus. But there's much more to be said about what it will take for a hospital to keep this bug from entering or spreading; more on that in a future post.
Before we get too much further from the initial news, I want to go back over the history of NDM-1's discovery — because, as with so many superbugs that take the public by surprise (recall the furor when the CDC's estimate of 19,000 MRSA deaths a year was published in late 2007), it turns out that there have actually been alarm bells ringing on this for a while. Largely, of course, unheard.
The first finding was in an older man of South Asian origin, living in Sweden, who went back to India in 2007, was hospitalized in New Delhi as a result of longstanding health problems, returned to his new home, was hospitalized there also in January 2008, and was discovered there to be carrying this resistance factor. The first public description of his case was made in October 2008, during a poster session at the annual ICAAC meeting (Interscience Conference on Antimicrobial Agents and Chemotherapy). That was later expanded to a journal article that was published in Antimicrobial Agents and Chemotherapy in December 2009; the full text is online in PubMed Central.
In the interim, though, the UK's Health Protection Agency published its first alert, in July 2009, describing 19 patients carrying this resistance in 2008 and the first half of 2009, 9 of whom had received medical care in South Asia:
One UK patient, who developed a bloodstream infection with an E. coli that produced NDM-1 enzyme had received treatment for a haematological malignancy in both India and the UK; two others had undergone cosmetic surgery in India and one of these presented to a UK hospital with a wound infection that grew a mixed microbial flora including K. pneumoniae with NDM-1 enzyme; others had received renal or liver transplantation in Pakistan.
Meanwhile, other researchers in Europe were becoming alert to the threat that NDM-1 posed if it were to spread widely; English researchers warned of it in September 2009, and Scandinavian researchers did the same in November 2009.
And in June 2010, the CDC published its first report and warning of NDM-1 in patients in the US, noting that all three, who lived in different states, had received medical care in India.
But what's important to note is that, despite the surprise and indignation coming from South Asia after the publication of last week's Lancet Infectious Diseases papers (article, editorial) describing the spread of NDM-1, the existence of that resistance factor has been discussed in Indian medicine since sometime last year.
From August to November 2009. a team of physicians at the Hinduja National Hospital and Medical Research Centre in Mumbai surveyed their ICU patients, and found 22 isolates carrying NDM-1. Their paper was submitted very quickly, in December 2009, and published in March 2010 in the Journal of the Association of Physicians of India:
We sought to identify NDM-1 positive strains among the carbapenem resistant Enterobacteriaceae isolates at our tertiary care centre. In a short span of 3 months, we identified 22 such organisms. The physicians at our institute follow the hospital antibiotic policy and do not indiscriminately use carbapenems. However being a tertiary centre we receive transfer in cases / referrals from other hospitals... The identification of NDM-1 in 22 of 24 isolates is a worrisome development indeed. NDM-1 being present among Enterobacteriaceae has the potential for further dissemination in the community. Such dissemination may endanger patients undergoing major treatment at centres in India and this may have adverse implications for medical tourism. Besides stringent infection control in hospitals, good sanitation in the community is also needed to contain the spread of such clones. (Deshpande et al., JAPI 2010)
News of their finding must have percolated through Indian medicine, because in January 2010 — before their paper was published — a worried letter discussing NDM-1, by a South Asian scientist working at the Royal Infirmary of Edinburgh, was published in the Indian Journal of Medical Microbiology:
The virtual nonexistence of antibiotic policies and guidelines in India to help doctors make rational choices with regard to antibiotic treatment is a major driver of the emergence and spread of multidrug resistance in India. This is augmented by the unethical and irresponsible marketing practices of the pharmaceutical industry, and encouraged by the silence and apathy of the regulating authorities. Poor microbiology services in most parts of the country add to the problem. (Krishna, IJMM 2010, DOI: 10.4103/0255-0857.66477)
And in March 2010, Dr. K. Abdul Ghafur of the Apollo Hospital in Chennai published a passionate and despairing call to arms ("An obituary — on the death of antibiotics!") alongside the Mumbai team's findings. The full text is online and it is worth reading in its entirety:
Our country, India, is the world leader in antibiotic resistance, in no other country antibiotics been misused to such an extent. Microbes are the ultimate warriors. They have sophisticated weapons and use ingenious methods of attacks. They have always been many steps ahead of us. Even in the twenty first century with all the developments in the modern medicine, when we face microbes, we feel helpless. Whatever weapons we had in the form of antibiotics, we ourselves have ruined them. Indian medical community has to be ashamed of the NDM-1 ("New Delhi Metallo-1") gene. Even though we have not contributed to carbapenem development, we have contributed a resistance gene with a glamorous name. The overuse of antibiotics is embedded in our Indian gene. It is an Indian tradition. (Ghafur, JAPI 2010)
That Ghafur's plea went unheard is all the more striking — because for almost a decade, Indian researchers had been reporting, in their own journals, a steady and troubling expansion of carbapenem resistance in Indian hospitals. More on that when I post next.
Posted by Maryn McKenna at 10:30 AM 5 comments:
Labels: gram negative, India, NDM-1
More on NDM-1
One of the frustrations of being a working journalist and a blogger is that, when a big blog-story breaks, you're likely already to be working on something else. And so it is, unfortunately, with NDM-1: I'm on a magazine assignment and will be off interviewing people when I should be blogging.
(This s a great time to recommend that, for any breaking infectious disease news, you follow Crof at H5N1 (@crof) and Michael Coston at Avian Flu Diary (@Fla_Medic), who are dedicated, thoughtful, nimble and smart.)
Since I last posted, there's been lots of additional coverage of the "Indian superbug." Much of it, blog and media, is just echo chamber cannibalizing of the earliest reports (including but certainly not only mine), but there are some important new developments worth noting, which I'll list below.
There are also some important points that are getting lost in the echo-chamber bounce: First, it is not correct to say that every person who acquired this was seeking cheap medical care or engaged in medical tourism; a few of them were treated on an emergency basis while traveling, and a few have no apparent healthcare tie. So this is not a situation of people seeking to save money and, as some commenters seem to be suggesting, receiving their karmic payback. (C'mon: Seriously?) Second, it is also not correct to say that every case of this has been linked to a hospital — it's quite clear in the Lancet ID paper that in South Asia, a number of the cases were community infections. So it is not just a case of hospitals that are dirty or have poor infection control (which by the way is a problem in the US as well, right?); NDM-1 is already a community bug, which will make detection and defense much more complex.
OK, curated list:
First, if you're interested in more from me, CNBC asked me to write up a piece about NDM-1, which ran Thursday; and Friday morning I was on the WNYC-FM (and nationally syndicated) radio show The Takeaway.
Second, the list of potential victims of NDM-1 is growing. Most of them have survived, so marking their cases is really a way of measuring the resistance factor's previously undetected spread:
The UK has released a new statement, updating its earlier warning, and says it has found "around 50" cases carrying NDM-1, an update from the Lancet ID paper. (Side note: This statement, and the earlier warnings, came from the UK's Health Protection Agency. The UK has just announced that it will be shutting down that agency in a cost-cutting measure. Great timing.)
The government of Hong Kong has announced that it has seen one case of NDM-1, but the patient recovered.
Canada has disclosed that it has had two cases, not the one mentioned in the Lancet ID editorial, in two different provinces.
Australia says that it has had three cases scattered across the country.
Belgium has announced one death.
And finally — sadly but probably not surprisingly — India is objecting to the stigma of being characterized as the source of NDM-1. The study's first author has disassociated himself from the paper and members of the government are claiming a "pharma conspiracy." Medical tourism has become a significant industry in India, and it is true some of these reports cast doubt on its safety. But still, I find this reaction disappointing.
Evading the stigma of an emerging disease is not a new impulse: Recall how the government of China suppressed for 6 months the news of the start of the SARS epidemic. They did not stop the epidemic, of course — it eventually sicked more than 8000 people across the globe and killed about 775 — but their suppression of the details of its spread kept other jurisdictions from mounting a defense in time. From my teaching gigs in Hong Kong I can testify how much bitterness endures in Hong Kong over this.
China's actions in 2002-03 led to the enactment of the new International Health Regulations by the WHO, which specify that, because expanding epidemics take no notice of borders, it is inappropriate for any government to attempt to impede the free flow of information about their spread. India is a signatory to the IHRs.
I am not suggesting that India is attempting any suppression of news about NDM-1 — there's no evidence of that — but the volatile language being used does concern me. I acknowledge that India is an extremely open society, with degrees of political expression that can sound surprising from this distance. But let's hope the government takes its commitment to the IHRs as seriously as any signatory should.
Posted by Maryn McKenna at 12:03 PM 4 comments:
Labels: Australia, Belgium, Canada, IHR, India国产CHINESE在线男同 , NDM-1, UK
NDM-1: Novel, global, complex and a serious threat
There's news today in the journal Lancet Infectious Diseases of the further spread of a troubling new resistance problem that I first talked about in June: Gram-negative bacteria carrying a novel resistance factor that has been dubbed New Delhi metallo-beta-lactamase, or NDM-1.
In writing about resistant bacteria, it's difficult to avoid overusing superlatives — but this resistance mechanism has spread widely, been transported globally, and brings common bacteria up to the brink of untreatable. It already has been found in India and Pakistan, Sweden, the Netherlands, Australia, Canada and the US, and has been distributed not just by travel but specifically by medical tourism. It has the potential to become an extremely serious global threat.
Necessary background: One major way that microbiologists classify bacteria is on the basis of the organisms' cell membranes; some have a single membrane, and others have two separated by fluid. The groups are identified by their response to a 4-step staining process, called Gram stain for the Danish physician who invented it in the 1880s. Cells that pick up the first stain applied, which is usually violet but sometimes blue, are single-walled; cells that resist the bath of the first stain, but pick up a lighter tint from another chemical in a later step, are double-walled. The single-membrane, dark-stained organisms are dubbed Gram-positive; the double-membrane organisms are known as Gram-negative.
Here's why that distinction is so important for understanding antibiotic resistance: Most of the drugs that kill or control bacteria act by attaching to or penetrating through cell membrane. The double membrane of the Gram-negatives presents a greater obstacle to drug-molecule interference than the single membrane of the Gram-positives — and thus makes developing drugs that can control Gram-negatives a more complex task. Hence, while there's abundant concern about the narrowing drug pipeline for Gram-positives including MRSA, there is even more alarm about the dearth of new drugs for Gram-negatives (as captured last year in this article from Clinical Infectious Diseases).
The novel resistance factor that is described today in Lancet ID appears only in Gram-negatives, primarily in E. coli and K. pneumoniae but also in other species. Bacteria that have acquired this mechanism are resistant to multiple classes of drugs commonly used against Gram-negatives: beta-lactams, fluoroquinolones, aminoglycosides, and most troublingly carbapenems, generally considered the drug class of last resort for those organisms. Several of the isolates found in the study were susceptible only to colistin, a drug that dates back to the 1960s and is considered toxic to the kidneys, and tigecycline, which was only licensed in the US in 2005. Several responded only to aztreonam. One was susceptible to nothing.
The real threat in today's news, though, is not only how resistant these organisms have become; it is also how they got that way, and how and by what means they are spreading.
As the Lancet ID paper reports, NDM-1 resides on a plasmid — a snippet of DNA, not on a chromosome, that reproduces on its own and can move freely between organisms. Intuitively, you would think that bacteria either inherit resistance from their progenitors or develop it on their own when they encounter a drug. Plasmids short-circuit both those processes, allowing resistance to spread rapidly within a single bacterial generation to organisms that have never experienced the drug they are acquiring defenses against. And as the paper testifies, NDM-1 has spread: The authors surveyed for NDM-1 in India, Pakistan and the UK, and found it both widely distributed in South Asia, and also present in UK residents who had family or business ties to South Asia, or had gone to the subcontinent for medical care. And unlike some resistant organisms, the bacteria carrying NDM-1 were not confined to the bug-friendly environment of hospitals or the the debilitated systems of hospital patients. Instead, it was out in the community, causing common illnesses such as urinary tract infections.
There are a couple of points embedded in that report that bear unpicking because they are so foreboding.
First, that this is happening in India, which not only harbors some of the world's largest manufacturers of generics, but also (and possibly synergistically) has some of the world's highest rates of antibiotic use. Some Indian researchers have been warning for years that the subcontinent is on the verge of a homebrewed crisis of drug resistance (Indian Journal of Bioscience, Indian Journal of Medical Microbiology, Indian Journal of Medical Ethics).
Second, that it is linked to medical care, and especially to medical tourism — which has become a booming international industry, not only for elective options such as cosmetic surgery, but because it offers an inexpensive way to perform major procedures that health systems might once have wanted to have done close to the patient's home. A study covered last January by The Independent in London recommended shipping UK patients to India for care, suggesting it could save the beleaguered health service more than $200 million.
And third, that these isolates were found in community infections caused by common organisms such as E. coli. That testifies not only to their wide distribution, but also to how difficult it might be to conduct surveillance for their presence — or, put another way, how easily they could evade detection while they continue to spread. It is not likely that physicians are going to culture every UTI that comes their way, either in the resource-poor developing world or in the overstressed conditions of Western medicine.
One example of the importance of surveillance: That's how NDM-1's first appearance in the United States was detected, via three isolates from three states that were tested at the CDC's national labs in the first half of this year. In a bulletin in June (the subject of my first post on NDM-1), the CDC urged clinicians to be alert for resistant infections in any patients who reported receiving medical care in India or Pakistan.
Unfortunately, given the drought of new drugs for Gram-negatives, surveillance may be the best bet for controlling or at least slowing NDM-1's further spread. It's the urgent recommendation of the author of a companion Lancet ID editorial, also published today (and who appears to have seen Canada's first case):
The spread of these multiresistant bacteria merits very close monitoring and worldwide, internationally funded, multicentre surveillance studies, especially in countries that actively promote medical tourism. Patients who have had medical procedures in India should be actively screened for multiresistant bacteria before they receive medical care in their home country. ...The consequences will be serious if family doctors have to treat infections caused by these multiresistant bacteria on a daily basis.
Kumarasamy KK, Toleman MA, Walsh TR et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. The Lancet Infectious Diseases, early online publication, 11 August 2010doi:10.1016/S1473-3099(10)70143-2
Pitout JDD, The latest threat in the war on antimicrobial resistance. The Lancet Infectious Diseases, early online publication, 11 August 2010. doi:10.1016/S1473-3099(10)70168-7
Posted by Maryn McKenna at 6:07 PM 2 comments:
Labels: global health, gram negative, gram positive, India, medical tourism, NDM-1
News break: CDC alert on imported novel resistance
This is an addition for archival purposes of a post that originally appeared at Scienceblogs.
There's a troubling item in this afternoon's issue of the CDC's Morbidity and Mortality Weekly Report or MMWR: The first report in the United States of a novel resistance mechanism that renders gram-negative bacteria extremely drug-resistant and that has been linked to medical care carried out in India or Pakistan.
The short item describes three isolates (E. coli, Klebsiella pneumoniae and Enterobacter cloacae国产CHINESE在线男同 ) found in three patients in three states between January and June of this year. All three isolates produced New Delhi metallo-beta-lactamase (NDM-1), which has never been recorded in the US before. Because of that novel mechanism, the three isolates were resistant to the carbapenems usually used on the most serious gram-negative infections, in fact to all beta-lactam antibiotics (penicillins, cephalosporins, carbapenems, monobactams, etc.) except for one monobactam, aztreonam -- and they were also resistant to aztreonam through another mechanism that hasn't been identified yet. All three of the patients found carrying this novel resistance factor had undergone medical care in South Asia recently.
This may be the first finding of this mechanism in the US, but it's been causing alarm in Europe for at least two years.
The first identification of NDM-1 was in 2008, in a 59-year-old resident of Sweden who was of South Asian origin and had returned to India for several months. The man was not well -- he had long-standing type 2 diabetes and had experienced a number of strokes -- and while in India he was hospitalized for an abscess, underwent surgery, developed bedsores and was treated for them as well. He returned to Sweden and was hospitalized there in January 2008, where physicians found him to be suffering from a urinary tract infection caused by a Klebsiella strain carrying this never-seen resistance mechanism.
Last July, the UK's Health Protection Agency put out a national alert about NDM-1, warning that the novel mechanism had gone from never-seen in 2007, to 4 isolates in 2008, to 18 in the first half of 2009. They were not an outbreak, but represented repeated importations: The isolates were clonally diverse and had been collected at 17 different hospitals. They were, instead, a sign that long-standing two-way population movement between England and South Asia -- augmented by elective medical tourism (two patients had gone to India for cosmetic surgery) -- was bringing the high rates of antibiotic resistance in India back to a UK medical system that is already challenged by serious infection-control problems.
And now it's here. The special challenge of NDM-1 (which as today's finding suggests is on a mobile genetic element that has carried the resistance mechanism between species) is not only that it adds to an accumulating rogues' gallery of resistance factors that are rapidly making gram-negative bacteria ferociously drug-resistant, but also that there are so few drugs under development for gram-negatives that truly untreatable infections are not far off. The UK clearly is already struggling with attempting to use drugs that are old and toxic, untested against these organisms (and therefore with no agreed-upon dosing), or wrong for the organ systems affected:
Treatment presents major challenges. Most isolates with NDM-1 enzyme are resistant to all standard intravenous antibiotics for treatment of severe infections. Polymyxin is usually active in vitro ... but of uncertain clinical efficacy, especially in pneumonia, owing to poor lung penetration. Tigecycline is often active in vitro, but has low serum levels, is unsuitable for urinary infections and, more generally, is of unproven efficacy in severe infections.
The CDC's alert today asks any clinicians who come up against carbapenem-resistant gram-negatives to ask about contact with India or Pakistan as part of history-taking, and to forward isolates through state public health labs to the the CDC.
Update + fodder: I flipped over to my RSS reader and also discovered this paper posted overnight by Clinical Infectious Diseases, about extended-spectrum beta-lactamases in a particular strain of E. coli ("an important new public health threat"), and this one in Emerging Infectious Diseases, about carbapenem resistance moving between Klebsiella and E. coli.
Labels: gram negative, India, NDM-1, UK
Maryn McKenna
Maryn McKenna is an award-winning journalist and author and a recovering newspaper reporter. She writes about public health, medicine and food policy for national magazines and medical journals, and finds emerging diseases strangely exciting.
SUPERBUG the book
SUPERBUG has been featured on Fresh Air with Terry Gross, NPR's Science Friday, CBC's The Current and other radio and TV as well as numerous print and online publications. Find it at Superbugthebook.com.
Excerpt here, praise here, media coverage and audio/video on this page.
Upcoming appearances are listed here.
I subscribe to the Society of Professional Journalists' code of ethics and the Association of Health Care Journalists' statement of principles. I am a board member of the Association of Health Care Journalists and a member of the National Association of Science Writers, American Society of Journalists and Authors, National Federation of Press Women and Online News Association.
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SUPERBUG: The Fatal Menace of MRSA
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Keep your savings in in this staunch black rabbit.
As soon as you have saved enough, you can collect your money stash via an opening in the bottom.
This coinbank measures 23 cm in width and 35 cm in height.


text:
Perisphaerus rubescens är en kackerlacksart som först beskrevs av Hanitsch 1933.  Perisphaerus rubescens ingår i släktet Perisphaerus och familjen jättekackerlackor. Inga underarter finns listade i Catalogue of Life.

Källor

Jättekackerlackor
rubescens


text:
[![Build Status](https://travis-ci.org/spbpython/kdpv_generator.svg?branch=master)](https://travis-ci.org/spbpython/kdpv_generator)

### purpose
generating images like this:

![sample1](https://secure.meetupstatic.com/photos/event/1/d/b/1/600_463327601.jpeg)
![sample2](https://secure.meetupstatic.com/photos/event/b/1/c/c/600_463125516.jpeg)
![sample3](https://secure.meetupstatic.com/photos/event/8/6/7/b/600_463174427.jpeg)

### features
- draw your image declarative way!
- cyrillic support
- custom fonts (ttf, otf) support
- use local or remote image files
- auto-crop image file to round form

### stack
Python 3.5/3.6 (<3.5 is not supported due to use of `typing` module.), Pillow

### how to use
- install system requirements (`cat system_requirements.txt | xargs apt-get install -y`)
- install python requirements (`pip install -r requirements.txt`)
- create data.yml from any of existing configs (for example, `cp kdpv_generator/configs/meetup.yml data.yml`)
- `python run.py`

### tests
the pytest is used for the tests.
to run the tests use command:
`python3 -m pytest`

### what can be improved
see [Issues](https://github.com/spbpython/kdpv_generator/issues).

redpajama_set_name: RedPajamaGithub


On the western coast of the Dutch province of Friesland, sits Stavoren. Now a popular holiday yacht haven and marina, visited by holidaymakers from many lands.
The lady in question was the widow of a successful merchant who had died, leaving her his fleet of trading vessels. In the years following her husband's death she had vastly increased the wealth of the business until she had now become by far the richest in the city.
One day she sent for her most experienced captain. "I have a special commission for you", she said. "I want you to prepare your ship as quickly as you can. Set sail and bring me back, 'The most precious thing in the world!' "Yes madam", replied the captain, "and what would that be?" "If I knew that", she said icily, "I would already have bought it! You are my most experienced captain, you must have many contacts throughout the world. I don't care how much it costs, just find 'The most precious thing in the world' and bring it to me. You will be well rewarded for your search" The captain left somewhat confused. However his employer was not one with whom he wished to argue.
The following day he began to prepare his ship for the long voyage ahead. News of the mission quickly spread, in the way that gossip does and by the time the ship was ready, a large crowd had gathered at the quayside to see it set sail. Much was the speculation as to what the captain would bring back. "A religious icon!", suggested one. "A pearl as big as an egg!" suggested another. "Perhaps a golden statue from Egypt!" thought someone else. None of them of course had any idea as they watched the ship slip away.
Time passed. The days turned into weeks The weeks became months and there was no sign of the captain's return. A year went by and people had begun to forget about the quest. And then, fifteen months after the ship had sailed away, A cry went out that it had been sighted entering the harbour!
"Wheat", said the captain. "I have brought a cargo of wheat." "Wheat? You have brought me wheat?" She nearly choked with rage" "Yes ma'am, what could be more precious than wheat? Without bread, half the world would starve!" The lady heard one or two sniggers of laughter from the people in the crowd. "And is this wheat all mine, to do with what I will?" she said quietly.
Worse was to follow. After a few weeks, the wheat that had been tossed from the captain's ship took root and began to grow on the sea bed, where it had fallen. Soon the sand, which had freely flowed back and forth with the water, began to clog and pile up among the growing stems of wheat. Within a year a sandbank had grown across the harbour mouth to such proportions that large ships were no longer able to enter the harbour. And so a once prosperous merchant shipping town went steadily into decline.
The sandbank that still lies across harbour entrance, is known appropriately as, 'Lady's Sand'.


Miyoung Lee, Ph.D., Weimo Zhu, Ph.D., Elizabeth Ackley-Holbrook, Ph.D., Diana G. Brower, M.S., Bryan McMurray, M.S.
It is critical to employ accurate measures when assessing physical activity (PA) barriers in any subpopulation, yet existing measures are not appropriate for persons with blindness or visual impairment (PBVI) due to a lack of validity or reliability evidence.
To develop and calibrate a PA barrier scale for PBVI.
An expert panel (n = 3) and 18 PBVI were recruited to establish content validity for a PA barriers subscale; 160 PBVI (96 females) completed the scale along with the Physical Activity Scale for Individuals with Physical Disabilities for calibration. To establish construct-related validity evidence, Confirmative factor analysis (CFA) and Rasch analysis were applied. To investigate internal consistency and reliability, Cronbach's alpha and the reliability coefficient (R) were employed, respectively.
Following CFA and Rasch analyses, five items were eliminated due to misfits; reliability coefficients were unchanged upon deletion of these items. The barriers perceived by PBVI to have the most negative impact on PA included "lack of self-discipline" (logit = 1.40) and "lack of motivation" (logit = 1.27). "Too many stairs in the exercise facility" (logit = −1.49) was perceived to have the least impact.
The newly-developed scale was found to be a valid and reliable tool for evaluating PA barriers in PBVI. To enhance promotion of health-producing levels of PA in PBVI, practitioners should consider applying this new tool as a precursor to programs aimed at improving PA participation in this group.


text:
Shorenstein Lands Trio of New Tenants at Bank of America Plaza in Atlanta, GA
Bank of America Plaza, Atlanta, GA
ATLANTA, GA July 30, 2018 – Shorenstein Properties LLC announced three notable lease signings today at Bank of America Plaza, a newly energized Class A office tower in Midtown Atlanta.
Christopher Caltabiano
The 55-story tower, the tallest in the Southeast, recently underwent a $10 million renovation to the building's West Wing that delivered an array of premier amenities, including state-of-the-art workspaces and a dynamic food hall featuring chef-driven concepts and healthy options.
Headlining the list of new tenants at Bank of America Plaza is Revel Systems, a San Francisco-based tech firm that transforms the way business is done across the globe by integrating all operations and customer channels, driven by the Point of Sale, into a single dashboard.
Jeff Keppen
Revel signed a 25,547-square-foot full-floor lease on the building's 38th floor and will move into upgraded, loft-style offices that are part of the tower's expanding spec suite program.
The owners were represented by Jeff Keppen and Nicole Goldsmith of CBRE. The tenants were represented by Christian Devlin of CBRE.
Outsized demand for the spec suites, which include open floor plans, creative lounge space and tech-enabled amenities, has spurred Shorenstein to accelerate development for the next block of spec suite space, which totals nearly 15,000 square feet and is expected to come online this fall.
Also as part of the spec suite program, Shorenstein unveiled lease signings with Groundfloor (7,746 square feet), the first and only real estate lending marketplace open to non-accredited investors, and Florence Healthcare (4,106 square feet), a fast-growing company focused on improving clinical trial data flow to advance cures through software.
"Our thriving spec suite program has established Bank of America Plaza as a market leader in high-tech loft space that will attract the most sophisticated tenants from Atlanta and beyond," said Christopher Caltabiano, Senior Vice President of Asset Management at Shorenstein Properties.
Nicole Goldsmith
"The demand for these next generation workspaces also coincides with the roster of new dining, retail and entertainment destinations in close proximity to Bank of America Plaza, creating one of the most dynamic work environments in the U.S.
"We welcome this impressive group of companies to the building, and look forward to providing an atmosphere that helps foster bottom-line results for our tenants."
Gregory Dukat
The crown jewel of Atlanta's skyline and one of the tallest buildings in the U.S., Bank of America Plaza is also home to leading tenants such as Anthem, Inc., Display Data, Featurespace and Riskalyze.
"Shorenstein's forward-thinking approach has fueled the impressive transformation of Bank of America Plaza into a premier tech hub," said Greg Dukat, CEO of Revel Systems, a feature rich Point of Sale and business platform. "The ability to access high-tech, move-in ready space in the heart of Atlanta was a key factor in our decision to open a new regional office here.
"Mass transit, great restaurants and other top attractions are within an easy walk of the building and will provide Revel Systems a considerable advantage in recruiting top talent from across the area. We look forward to calling the building home for many years."
As part of the recent West Wing renovation, Shorenstein debuted Marketplace 600, a 17,000-square-foot food hall that includes a "Chef's Table" which showcases the skills of celebrity chefs who frequently visit the building. Marketplace 600 features a variety of food stations, including a salad bar, hot meal bar, grill station and dessert bar, and also offers cooking classes and digital order and pick-up through the Thrive mobile app.
Christian Devlin
The upgraded West Wing also features a new 4,000-square-foot conference and event center, along with a new Bank of America branch. Other on-site amenities include the 17,000-square-foot RPM Health Club & Spa that offers personal training, group classes and massages, and a full-service Starbucks in the main lobby.
Bank of America Plaza is directly adjacent to the North Avenue MARTA rail station, and offers immediate north and south access to Interstates 75 and 85. Mercedes-Benz Stadium, World of Coca-Cola, Ponce City Market and the Georgia Institute of Technology are all within close proximity to the building.
More than 63 restaurants are also located within five blocks of Bank of America Plaza, including Publik Draft House, Edgar's Proof & Provision, Baraonda Ristorante & Bar and Livingston.
Liana Moran
lmoran@thewilbertgroup.com
Labels: Shorenstein Properies Bank of America Plaza Office Tower Midtown Atlanta GA 7-30-18
The Madison Sale Brings EverWest's Phoenix Transaction Volume to $165 Million in 24 Months
The Madison Office Campus, Camelback Corridor, Phoenix, AZ
Amr Ceran
Phoenix, AZ – EverWest Real Estate Investors, in partnership with CenterSquare Investment Management, has completed the sale of The Madison, a Class A office campus located in the heart of Phoenix's Camelback Corridor.
The sale marks a $165 million, 24-month transaction and renovation push within metro Phoenix by the Denver-based real estate investment, management and operating company.
Kevin Shannon, CJ Osbrink, Paul Jones, Ken White, Brunson Howard and Rick Stumm of NKF Capital Markets represented EverWest and CenterSquare in the transaction.
Located at 5343 and 5353 N. 16th St., The Madison totals 177,312 square feet of Class A office space in two four-story buildings – both offering views of the surrounding skyline, Camelback Mountain and Piestewa Peak, and quick access to area amenities, including some of the Valley's most sought-after shopping and dining destinations.
Kevin Shannon
Since purchasing The Madison, EverWest has completed an extensive repositioning program including renovations to lobbies, restrooms, conference facilities, monument signage and landscaping, and the addition of an on-site deli offering quick-serve lunch and dinner items.
"EverWest has executed on its business plan," said EverWest Senior Director Amr Ceran, who manages the company's Arizona and Southern California real estate portfolio, including investment, redevelopment and lease-up.
"Our focus is on acquiring and renovating assets through extensive improvements and lease-up, with results that achieve – and often exceed – market rates."
EverWest's Phoenix activity over the past 24 months has included the sale of Great American Tower – a landmark downtown Phoenix high-rise office building that the company improved prior to sale, and the sale of 10 Chandler, a 553,000-square-foot flex/industrial building located in the Chandler Tech Corridor, fronting Interstate 10.
CJ Osbrink
In 2016. the company renovated The Circuit from a former semiconductor building into 185,000 square feet of creative office space.
The same year it purchased and began efforts to transform The Quad from outmoded executive suites into a 14-building, 166,606-square-foot project that blends elements of a lifestyle center and office park to create a next-generation creative office community.
In late 2017, EverWest completed the purchase of – and is currently renovating – Seville Professional Center, a two-story building totaling 92,581 square feet on North Scottsdale Road.
At The Madison, renovations and a successful lease-up plan has achieved 90 percent occupancy.
Stacey Hershauer/FocusAZ
stacey@focusaz.com
www.everwest.com
www.gwlra.com.
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When your love story begins with a first date at the Inn on Pamlico Sound, it is only fitting to start your new lives as husband and wife there too! An Outer Banks Affair guided Hatteras Island locals, Danielle and Aaron, in creating a wedding day that was surrounded in pink with hints of Southern charm. From the personalized programs by HLR Designs and the fun-filled decor by Renee Landry Events to Distinct Delights confections and glamorous linens by Ocean Atlantic Event Rentals, Daniel Pullen Photography is helping us sharing this Pamilco pretty affair featured in the 2016 Outer Banks Bride Magazine.
View more from Danielle and Aaron's wedding, receive Outer Banks wedding inspiration and receive our in-demand vendor directory by reserving your complimentary copy of the 2016 Outer Banks Bride Magazine.
How He Asked: "Despite living on Hatteras Island, Danielle had never climbed the Cape Hatteras Lighthouse before, but had talked about it frequently. Aaron arrange a climb to the top of the lighthouse on early evening where he proposed once they arrived to the top."
Why They Chose the Outer Banks: "We both live and met on Hatteras Island, so it seemed like the perfect place to have our special day to share with our friends and family from near far. There's no place like home!"
Weddings Inspiration: "We wanted to incorporate all things on Hatteras Island that are special to us. The Inn on Pamlico Sound is where Aaron took me on our first day and we couldn't have imagined having our wedding anywhere else. Danielle's mother was a huge part of the wedding planning and spent a year planning every detail to perfection."
Favorite Wedding Memory: "One of our favorite wedding day memories is being able to get away after the ceremony. Just the two of us with Kate and Daniel Pullen to take pictures at the Cape Hatteras Lighthouse where we had gotten engaged."
Allowing the ocean to be their inspiration, Lauren and Tyler chose a color palette that mirrored its brilliant hues, from light shades of sea foam to rich hues of teal. Renee Landry Events added pops of pink to Lauren's bouquet and created white calla lily bouquets for the bridesmaids that matched the beach-styled reception tablescapes. Basnight Photography captured all of the details of this modern destination wedding at Koru Village & Spa, featured in the 2016 Outer Banks Bride Magazine. We are over-the-moon to share this gallery of ready-to-pick inspiration for your Outer Banks wedding!
View more from Lauren and Tyler's wedding, receive Outer Banks wedding inspiration and receive our in-demand vendor directory by reserving your complimentary copy of the 2016 Outer Banks Bride Magazine.
How He Asked: "Tyler knew he wanted to propose somewhere special to he and Lauren, and since they've been going to the Outer Banks with their families for years, he knew that was the perfect place. On the first night of their vacation in Avon, they went for walk walk on the beach and when they reached the Avon Pier, Tyler popped the question!"
Why They Chose the Outer Banks: "We've been coming to the Outer Banks with our families for vacation for years, and since Tyler proposed there, there was no question that we wanted to get married in Avon too!"
Wedding Inspiration: "Our decor was all beach themed! The color palette included ocean tones, and the wedding style was beach chic. We wanted our wedding to reflect the surrounding of the venue."
Favorite Wedding Memory: "Our first dance. It was one off the only times during the evening when we were able to have a conversation, just the two of us, without people running up to congratulate us! As strange as it was to be the only two people dancing in a room full of people, for those few minutes, it felt like it was just us."
Creators and technicians of incredible wedding lighting designs, Blue Steel Lighting Design uses cutting edge technology to execute your dream wedding atmosphere. Whether you desire a glamorous, sparkling chandeliers or a reception flushed with bright color, Blue Steel Lighting Design can expertly craft lighting that will leave your wedding guests speechless. We are honored to have these experts in event and architectural lighting as a member of the Outer Banks Wedding Association and know will love every minute of working with John and his team!
To learn more about Blue Steel Lighting Design, contact John and Simone at 252-548-9622 or via email: bluesteelobx@gmail.com.
If you are looking for a photographer that will make you feel more like family than a client, then Outer Banks Productions is the perfect photography team for you! With 12 years of experience and over 600 weddings under their belt, Michelle and Douglas are the husband and wife team behind this reputable Outer Banks photography business. Capturing everything from portraits and candids to detailed shots, Outer Banks Productions offerings wedding photography and photo booth rentals from Carova to Hatteras Island. We love that they are able to customize packages to meet many budget sizes too!
To see if Outer Banks Productions is available for your Outer Banks wedding, contact Michelle and Douglas at (252) 480-3074 or via email: weddings@outerbanksproductions.com.
When it came to planning this nautical-themed wedding, the rustic ambiance of the Hilton Garden Inn's Kitty Hawk Pier was the perfect venue to host Lauren and Hunter's aquatic affair. Our favorite part of their darling wedding was the "message in a bottle" toss during their pier ceremony, officiated by Rev. Jay Bowman! Using the love letters exchanged that morning, they placed the letters in a bottle and tossed it into the ocean during the ceremony. With Kristi Midgette Photography capturing all of the unique, memorable moments of this Outer Banks Bride Magazine feature wedding, we're unlocking more steal-worthy details of this Outer Banks destination wedding.
View more from Lauren and Hunter's wedding, receive Outer Banks wedding inspiration and receive our in-demand vendor directory by reserving your complimentary copy of the 2016 Outer Banks Bride Magazine.
How He Asked: "Hunter proposed at a vineyard in Louisa, Virginia. We were out celebrating my birthday and the completion of my teaching license. The next thing I knew, the music stopped and Hunter was down on one knee with a diamond ring tied to a wine glass! In a tasting room full of family and friends, he asked me to marry him."
Why They Chose the Outer Banks: "Hunter and I always dream of having a beach wedding. We visited the Outer Banks and feel in love with its beauty. We both love to fish, so deciding to get married on the pier was perfect for us! We love the rustic feel of Kitty Hawk Pier and knew right away that was the place we were meant to start our forever."
Wedding Inspiration: "We wanted to incorporate a navy and white striped nautical theme, but keep it elegant and classic at the same time. It was all about the details when it came down to planning. I wanted everything to be absolutely breathtaking, and it was!"
Favorite Wedding Memory: "We chose to incorporate a message in a bottle as part of our ceremony. Hunter and I exchanged letters to each other the morning of our wedding, delivered by Hunter's best man. We read each others letters and put them inside the bottle afters to send off to sea. We threw this bottle off the pier into the waves as part of our ceremony. It was a beautiful moment and we can't wait for someone to find that bottle someday!"
When you get engaged in Brazil, it is only fitting to draw inspiration its the tropical foliage when planning your Grande Ritz Palm wedding. From the bohemian blooms by Renee Landry Events to the decadent menu by Cafe Lachine, Engaging Events aided Meghan and Mark in creating a homegrown jubilee with vibrant flare. With Daniel Pullen Photography behind the lens, this grande celebration completely won us over and we are so excited to feature these Corolla natives in the 2016 Outer Banks Bride Magazine!
View more from Meghan and Mark's wedding, receive Outer Banks wedding inspiration and receive our in-demand vendor directory by reserving your complimentary copy of the 2016 Outer Banks Bride Magazine.
How They Met: "Mark and I met seven years ago when I worked at his restaurant, Metropolis. I was a pretty terrible waitress and decided to go back to school to become an art teacher. Two years later, we ran into each other at a concert in Virginia, and have been together ever since! Today, we still have the pleasure of working closely together, because I now own an art studio next door to Metropolis!"
Why They Chose the Outer Banks: "It's our home! We live in Corolla and my parent's live in Duck, just across the street from the Grande Ritz Palm. We feel so lucky to call such a beautiful place home, and couldn't have imagined getting married anywhere else."
Wedding Inspiration: "Mark proposed while we were on vacation in Brazil, and the beautiful flowers we saw there definitely inspired our wedding theme. I wanted a tropical, bohemian vibe with lots of greenery - palm and banana leaves - and dark, dramatic pops of color. The Grande Ritz Palm was the perfect backdrop, and everyone at Renee Landry Events did such an amazing job bringing my ideas to life!"
Favorite Wedding Memory: "What I love about our wedding was that it was so us! It was a perfect day full of happiness and laughter! Since we live on the Outer Banks and Mark is in the wedding industry, many of our friends are our friends! From my hair and makeup to our officiant and caterers, we knew we were in great hands with people who care about us."
We hope you're ready, because your beach day on the Outer Banks is about to be taken to a whole new level. From set-up to break down, Beach Masters handles it all while you can sit back and enjoy the beach! Offering a variety of amenities that include tents, blenders, coolers, corn-hole and more - we can't think of a better way to celebrate your wedding week than with a beach party with Beach Masters!
To learn more about Beach Masters and to book their services for your Outer Banks vacation, Tom at 252-689-8200 or via email: tomk@beachmasters.net.
Several celebrations, continuous laughter, endless fun and countless memories - Brian and Brandon's Outer Banks wedding week was nothing short of spectacular! The Proper Setting aided these two in designing a festival of love throughout the entire week, ending with vows on the grounds of Whalehead in Historic Corolla. Gussied-up in cafe lights, rustic seating, wagon wheels and whimsical blooms by Bells & Whistles, these gents flawlessly decked out their event home reception all captured by Genevieve Stewart Photography!
View more from Brian and Brandon's wedding, receive Outer Banks wedding inspiration and receive our in-demand vendor directory by reserving your complimentary copy of the 2016 Outer Banks Bride Magazine.
How He Asked: "Our engagement story is nothing short of comedic! Brandon planned an elaborate scavenger hunt across Durham, North Carolina that incorporated several of our closest friends who road tripped or flew in from all over the country. When I drove down South to meet Brandon, we ran into a couple snags that made us run behind to begin the hunt but it wasn't too long that I was handed my first clue...one I didn't understand at all! We drove throughout Chapel Hill and Durham making several stops, where we were met by our closest friends who held more mementos and more clues. We eventually ended up at the last stop, a hotel room covered in photos where I open several small bags that contained puzzle pieces. We put the puzzle together which was a picture of the two of us and the caption, "Will You Marry Me?" Of course, I said "yes!" and shortly thereafter our friends came through cheering as we celebrated with champagne!"
Why They Chose the Outer Banks: "We use to have a home in South Nags Head when I was younger and Brandon loves the water, so when he suggested the Outer Banks we both thought its beautiful and serene environment would provide us the perfect backdrop for our wedding vision."
Wedding Inspiration: "Brandon and I both love the natural elements of the outdoors. We wanted a simple ceremony that focused on our story, our love for one another and that incorporated the many important people in our lives. We also love a good party and to dance, which is why we felt as thought we had to have a big dance floor that overlaid part of the pool. We asked Bells & Whistles to refrain from large centerpieces and use moss, candles and subtle flowers to create a tablescape that transformed out dining area into a wonderful woodland and that would highlight the beauty of simplicity. Our guests felt like they were transported away from the poolside into a beautiful forest with our rustic tablescapes and lighting!"
Favorite Wedding Memory: "Hands down, our favorite memory is our first dance. I love country music and the song we chose, 'Who I am With You' by Chris Young truly reflects our relationship. Being a gay couple, it was difficult for both Brandon and I to come out to our friends and family, but in the end it doesn't matter what other people thought of our relationship. We had each other and we could be ourselves and be honest with one another - this song reflected that!"


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Eminem Recalls The Time Val Kilmer Saw Him Naked
Jacinta Howard Published: May 29, 2018
Getty Images for Coachella
Eminem has been the source of a lot of talk lately. But in addition to the Nicki Minaj dating rumors, Eminem went on Instagram to spark even more discussion—specifically about the time that actor Val Kilmer saw him naked.
"This is like a confessional. I have something on my mind that's been bothering me for years, and I will tell you a little story," Em said on IG.
He says it all went down at either the VMAS or the MTV Movie Awards, he can't exactly remember which, but he does know that Kilmer saw him in all his glory, and told him, "I'm your huckleberry." Kidding. But Eminem did say things were a little awkward.
"My trailer was next door to 50 [Cent]'s trailer," he said. "I went to the back to go change for stage and as I'm taking off my underwear, I look across in 50's trailer, right even with me, is Val Kilmer sitting like this in a chair. And I know he's looking at me, and I know he looked away because he saw me looking at him. I know Val Kilmer saw me naked. I just had to get that off my chest."
In the meantime, Em is heavy on the festival circuit—he'll be at Governor's Ball and Bonnaroo next month.
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Source: Eminem Recalls The Time Val Kilmer Saw Him Naked
Filed Under: Eminem
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Facebook and Twitter just aren't enough. When you're limited by characters, it's hard to show what's all the exciting things taking place behind the scenes. Please follow us a bit deeper as we prepare for 2012′s Marathon Race Series. If you have anything you'd like to share, always feel free to email us at Sparky@prairiefiremarthon.com.
Buckle up! The countdown to race day begins!
Have you seen us up in the bright lights around town? Hopefully the town will be covered with Sparky in the weeks to come!


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I am still not quite to the point of a couple guys on OCN, but for CL16 2933 this is about all I am getting.
Very impressive stuff Wish I could have one!!
I got a pretty cool Cinebench ST Single Thread score of 236 with an 8086K, using a Noctua C14S air cooler.
Great for single and slightly threaded work apps and of course gaming.
But it's a Single-Threaded BEAST!
Got a solid result with a 4690K. 4.6 GHz core(1.286volts), 4.2 GHz cache.
Similar single core as 5775C at 4.3 with multi-core only behind by about 200.
1602 score, Xeon E5-1680 v2 @ 4,5GHz on Air Cooling.
FYI : 1574 point score in my case was done with ~4,4GHz clock.
Wine 3.0.3 @ Linux 4.18.10. It is likely it will run faster on native Windows installation.
PS. Memory: 4x 16GB DDR4 UDIMM ECC (Samsung M391A2K43BB1-CRC) running at 3200MT/s, 1.2V (but BIOS is saying 1.362V). tCL=17 (10.6ns). Still tweaking and testing stability. (Performance is similar on tCL=19).
Here is the score of my old CPU 4790, it dates back to may'17 I had that CPU for a month before switching to 5775c. Originally I had 4690k since 2015, u can see its result (708@4.5.Ghz) as well.
Hi and welcome to TPU!
-understandably but unfortunately, the memory is running dual channel only, due to it being quad kit and two for each cpu, no sticks available, making the procs starve for bandwidth, ideally they would work with eight sticks or more for octal channel, as opposed to quad right now.
-Also, despite good performance, the cpus are very expensive and offer no value for $, being only 3.1 ghz max; an engineering sample of QS stepping would have been more affordable.
-That asus motherboard is also known for problematic configuration and deployment, not working well with certain combos, failing with others.
-At that speed, the procs could bottleneck the 1080ti due to sheer clock speed, not allowing any overclocking or turbo unlock, being Broadwell-E.
Nevertheless, I am sure you could enjoy that rig for crunching or rendering, If you can configure it for less power consumption.
I still can't breath... not sure why the silicon gods were nice for a change (from 8700K 5GHz at 1.368v). 1 hour realbench, 2 hours bf1. Still doing more stress tests. BTW, this is on custom H20.
R2700x, b450 mobo, 3200 ram, 240mm aio, 750w psu.
I think with a better mobo" im using a aorus elite, not a great overclocking board" I should be able to hit 2000 with 4.3 and a bit more voltage, I did try 4.3 with the same voltage but scored 1905 and crashed, I dare not go above 1.4 with this board its very basic. what do you think my next mother board should be ?.
this is from the rig I use to run my telescope in my obsy, its a fx8350 with a tiny overclock, its 7 years old with 16gb ram @1600 and its never missed a beat.
no difference with the new update with the ryzen still 1907, ill try the FX in the morning its raining outside so don't wont to let the damp air in my obsy.


text:
Syringa vulgaris 'Heavenly Blue'.
Photo: Jardin botanique de Montréal (Gilles Murray)
Lilacs are fragrant flowering shrubs that are easy to grow and remarkably vigorous and long-lived. They are suitable for planting in both large and small gardens. In addition, you can stagger blooming times by planting a variety of cultivars.
Lilacs or Syringa belong to the Oleaceae family. This botanical family includes various plants that are very important in agriculture, silviculture and horticulture, including ash and olive trees, forsythia and jasmine.
There are some twenty natural and hybrid Syringa species. Most of the natural species are native to southeastern Europe and eastern Asia, especially China. Lilac shrubs vary in height depending on the species, and bloom in a wide range of colours.
The main lilacs
Syringa vulgaris, the common lilac so beloved by our grandmothers, is native to southeastern Europe. It was introduced to Central Europe in about 1563 by Ogier Ghislain de Busbecq, Austrian Ambassador to Constantinople (Istanbul). The forms with single violet or white blooms that are such a familiar part of our rural landscape were brought to North America by early European immigrants.
In the late 19th and early 20th century, various lilac cultivars were created in Europe, by the famous French breeders and nursery growers Victor and Émile Lemoine, among others. These new cultivars were dubbed French lilacs, designating the group of common lilac cultivars that bloom in late May*. The number of Syringa vulgaris cultivars has continued to grow, thanks to the work of European and North American breeders. The Royal Botanical Gardens, in Hamilton, Ontario, is today the international registration authority for new lilac cultivars.
Another group of lilacs, known as hyacinth lilacs (Syringa x hyacinthiflora), includes hybrids between S. vulgaris and S. oblata. These lovely shrubs flower early (around mid-May) and, depending on the cultivar, have highly fragrant single or double flowers. The Clarke's Giant cultivar has one of the largest flower panicles in this group.
A third group, named Syringa x prestoniae, or Preston lilacs, in honour of Isabella Preston, of the Ottawa Experimental Farm, includes hybrids bred from a cross between S. reflexa and S. villosa. These vase-shaped lilacs bloom later (around mid-June) than the first two groups. Their leaves are ruffled and their small tubular flowers are lightly scented. These lilacs produce few if any suckers.
A fourth group includes some lovely Asian lilacs: Amur tree lilacs (S. reticulata ssp. amurensis), Japanese tree lilacs (S. reticulata ssp. reticulata) and Peking tree lilacs (S. reticulata ssp. pekinensis). Some cultivars in this group can grow up to eight metres tall. These species may be grown as trees or shrubs. They are late bloomers (early July), with creamy white flowers and gold-hued bark. S. reticulata 'Ivory Silk', a very popular cultivar, has a more tree-like shape than the species.
The hybrid species Syringa x chinensis has attractive small, dense leaves and small pale mauve flowers that appear in early June.
Syringa x persica is a highly prolific bloomer, with strongly fragrant pinkish-lavender flowers.
Syringa villosa is a vigorous bushy shrub that makes a good container plant. It flowers profusely in mid-June.
Syringa meyeri 'Palibin' is a compact, dwarf cultivar (1.5 m), suitable for a hedge or rock garden. It can also be found top-grafted. The small pale mauve flowers appear in mid-June. Some years, the small, delicate leaves turn a lovely orangey colour in fall.
Syringa patula 'Miss Kim' is another small, compact lilac. It produces pale mauve flowers in mid-June and is suitable for planting as a specimen or for use as a screen. The leaves may turn burgundy in fall.
Syringa 'Bailbelle', sold as Tinkerbelle, is a dwarf cultivar with tubular pale pink flowers. It is a hybrid of S. microphylla 'Superba' and S. meyeri 'Palibin'.
Lilacs can be used in a wide variety of ways. They may be planted as specimens, to form hedges or screens, in rock gardens or as patio plants. The following growing tips will help you keep your lilac vigorous and encourage abundant blooms.
* The blooming times indicated in this leaflet are approximate dates for the Montréal region and may vary depending on exposure and weather in a given year.


text:
Vibrant new square and community building officially launch in Cambridge
7th November 2018 Editor, Estate Agent News City Property 0
Cambridge City Council has officially launched Hobsons Square and the Clay Farm Centre in Trumpington, Cambridge. The attractively designed square has been designed to be a focus for the community, hosting a range of local facilities and services including shops, a large sculpture, seating, rainwater gardens and an open plaza.
Complementing Hobsons Square, the impressive four storey Clay Farm Centre is a vital new addition for Trumpington's residents, boasting a large 250 person community hall with retractable, tiered seating. It offers a range of conference and meeting rooms, a public library and a café plus a dance and exercise studio. The building will also accommodate a health centre, Trumpington Medical Practice, and has apartments on the upper floors.
The new square and community building were designed together, and in consultation with local residents, so that functionally and visually they complement each other and meet the needs of the area. This flexible space gives Trumpington's community a hub in which to meet and socialise, while accommodating a wide range of open air events.
The official launch of Hobsons Square and the Clay Farm Centre was presided over by the Mayor of Cambridge, Cllr Nigel Gawthorpe, in a ribbon-cutting event held on Saturday, October 27th. To mark the special occasion, a series of indoor and outdoor activities were organised including street games, table tennis and climbing, among others. To showcase the versatility of the new building, a wide range of impressive shows were also held, including a drama performance, magic show and even a pop-up circus.
The Friday evening leading up to the launch also offered plenty of entertainment, with a family disco and light switch-on event being held.
The events on both days received support from BPHA.
Cllr Katie Thornburrow, Executive Councillor for Streets & Open Spaces at Cambridge City Council said:
"The new centre already offers the Trumpington community excellent facilities for a wide range of activities, and the opening of Hobsons Square will significantly enhance the building and what it offers."
"I'm looking forward to seeing how the external spaces are used with the public art and building elevation as a backdrop – the designers have done a great job, and I know that the community here is full of ideas and enthusiasm. This is reflected in what has already started happening here at the Centre and around the new developments."
Andrew Carrington, Managing Director of Strategic Land at Countryside, comments:
"The official opening of Clay Farm Centre and Hobsons Square represents a major milestone in bringing the local community together."
"Great Kneighton, along with the wider Trumpington area, will benefit from an array of new facilities and services, all designed to make life here even more inclusive."
In the centre of Hobsons Square is also a stunning new sculpture, known as the "Bronze House". Crafted by renowned artists Heather and Ivan Morrison, the piece was inspired by archaeological discoveries on the site dating from the Bronze Age.
The Clay Farm Centre is operated by Cambridge City Council in partnership with Cambridgeshire County Council.


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Anybody who has tried to get a loan in this low interest rate environment knows getting one isn't necessarily easy—even if you're wealthy and/or have a sterling credit score. But, the Small Business Lending Fund (SBLF) just got $214 million from the Treasury as part of the Small Business Jobs Act.
This addition brings the total of SBLF lend-out moola to $337 million.
Small businesses are big business in America. In case you didn't know they keep about 50 percent of us working and create about 60 percent of the jobs.
If you're a small business owner in need of funding go for it. And if at first you're turned down, try, try and try again. Tenacity pays off!