Whether it's for crowd control, asset/property protection, or concierge/security services, security guards are the ideal choice for those who need total peace-of-mind. However it's important to find the right company or service that fits your needs as more often than not you're placing them in a position of trust. For this reason hiring the right company is important and it's worth taking time to do a bit of ground work.
So why would you hire a security guard anyway?
What type of jobs would a security guard taken on?
What do you need to ask a potential security company?
Like most positions of trust, relevant experience is crucial. Therefore it's important to ask the company whether they can supply you with background knowledge of any potential candidates within their company. There's also nothing like a gut feeling, so with this in mind, it's also a good idea to speak directly with the candidates so that you get a better impression of the people that you're directly trusting your business, family, property, event or assets with. Finally check all licenses and make sure that they're valid.
What about after the company has been hired? What should you do then?
Firstly, information is key. The more clear and concise the directions the smoother and hassle-free the job will be. An experienced security company knows that the 'devil is in the detail' and as such will work with you to go over the finer points of the operation so that they can then brief their teams/personnel.
So there you have it! Everything you need to know about hiring a security company.
If you need total peace-of-mind security then contact MA Services Group. We provide a wide range of security services, using only highly trained professionals with a minimum of 3 years experience. So act now and contact us on 03 9994 4107 for a competitive quote today and let us take care of your security issues.


My name is Brendan Harley.
Biomolecular Engineering department at the University of Illinois.
tissue engineering theme here at the Institute for Genomic Biology.
My research is in biomaterials and digital engineering.
how we can treat them.
what we really think about is changing the way people practice medicine.
people outside of the standard medical field to make an impact.
the realm of thinking about what you do in Star Trek.
Where all of a sudden, they'd come up to you.
You have some sort of injury and there'd be a magical fix.
And there's a lot of stuff that we do there.
And so really we're trying to envision the next generation of medicine.
is that I love playing with LEGOs and models and all these things.
And when I was 17 I was diagnosed with leukemia.
was fascinated by how the biology could have worked to save my life.
being taken about 12 times by the resident and all the interns following them around.
And being 17, I was in a adult hospital.
30 years until I was the closest in age to all the doctors.
what they did in terms of research and how that impacted their medical careers.
And I went to Harvard.
biology, and medicine, and engineering was a really transformative thing.
a strong history of research and a strong history of liberal arts education.
I mean I wouldn't be here without having gone through that.
seeing about a third of my research is in the area of bone marrow transplants.
without having the chance to be a patient.
then you get a better sense of how you might be able to contribute.
understanding the side of the patient, understanding the science.
How do you make an impact?
it's really, the things that we work on in bioengineering are helping patients.
a patient and those things are important to understand.


'We are made of the Earth' chant inspires the spirit to align to Earth's natural rhythm and sound of nature. Whenever human circumstances or stressors toss spirit off blance we must return to nature. Flowers don't question when it is time to bloom. May we follow their lead and sing to their vibrational frequency to recalibrate our bodies, minds and spirit to our natural state of being. It's that simple.


Watch Out for the Tree-of-Heaven - clclex's JimdoPage!
The Plant Materials Guide for Lexington lists exotic invasive plants as well as plants native to Lexington. Knowledge about invasive species like the tree-of-heaven (Ailanthus altissima) is important in protecting the native environment. The tree-of-heaven was introduced from China to North America as an ornamental tree in 1748 by a Pennsylvania gardener. These trees became available from nurseries in 1840 and were widely planted in cities. According to the US Department of Agriculture, they currently grow in 42 states in the US. Tree-of-heaven is included in a list of plants that Massachusetts has prohibited for sale, trade, purchase, or distribution. Though trees-of-heaven are attractive, they are highly invasive. They crowd out native plants that are good for the environment and produce toxins that inhibit colonization of other plant species nearby.
Trees–of-heaven grow fast and can reach about 80 feet in height. The trees are dioecious—male and female flowers occur on separate plants. The flowers are small and pale yellow to green. Flat-winged reddish fruits, each containing one seed, are produced on female trees in late summer or early fall and persist on the trees in winter. The fruits gradually turn to tan. They are on terminal clusters of the trees' branches. Trees-of-heaven have compound pinnate leaves—they are structured like a feather with leaflets on both sides of the stem, sometimes with a terminal leaflet at the end. The leaves are 1- 4 feet in length with 10 to 41 leaflets. Young sumac shrubs, which are good for the environment, look somewhat similar to young trees-of-heaven.
The seeds of trees-of-heaven are dispersed by wind and water. They produce a prolific amount of seeds. One study found that one tree-of heaven could produce more than 300,000 seeds a year. In addition to reproducing by seed, the trees frequently reproduce through vegetative sprouting from roots. The seedlings can grow to 3 – 6 feet in the first year and root sprouts 10 – 14 feet in that time. Trees-of-heaven form dense thickets. The main vulnerability of the tree-of-heaven seems to be its lack of shade tolerance. Thus, it thrives at forest edges, in disturbed or harvested forests, in abandoned city lots, along roads, and in meadows. Trees-of-heaven also are not flood tolerant.
Chopping down a tree-of-heaven does not get rid of it because it produces large numbers of sprouts from the roots. The root system is extensive and hard to eradicate. However, repeated cutting of sprouts over time may eventually exhaust the plant's reserves. Chemical methods of control are most effective. Two fungal pathogens that have been found on dead trees-of-heaven are being investigated as possible biological controls.
Trees-of-heaven can be found in people's yards, in conservation lands and other open spaces, and along many roads in this area. Particularly noteworthy are the large numbers of tall trees-of-heaven along Rte. 2 in Arlington, with many smaller ones coming up in front of them reaching for the sun. West Farm, a small Lexington conservation area, has many young trees-of-heaven spreading into the meadow just in front of the older trees. This scenario is found all over. On a family trip to the Great Smoky Mountains National Park in 2010, we drove on federal highways lined thickly with trees-of-heaven, sometimes with long stretches of them at a time, in all the states from Massachusetts to Tennessee.
If a seed of a tree-of-heaven floats into your yard and starts growing—which is quite likely given the number of trees-of-heaven around—you should dig it out right away and make sure every piece of root is gone. These trees are extremely invasive and destructive to the environment, as are many alien plants. For those who find trees-of-heaven attractive, 5 species of trees listed in the Native Plant Guide for Lexington have deciduous, compound pinnate leaves similar to those of the tree-of-heaven, but they also provide food and cover for wildlife and have other good attributes.
Green ash (Fraxinus pennsylvanica): This dioecious tree grows 30 – 75 feet tall with a trunk diameter up to 20 inches. Its leaves are up to 6 - 9 inches long divided into 5 to 9 leaflets, each about 3 - 4 inches long. The deep-green leaves turn yellow in fall. Both male and female flowers are not conspicuous. The fruiting period is in September and October; the fruits persist through winter. About 10 species of birds eat the seeds from the winged fruits (samaras). This tree is also a larval host to caterpillars of 6 species of butterflies. It grows well in sun, partial shade, and shade and in dry, moist, and wet neutral soil.
White ash (Fraxinus americana): This ash has a straight trunk with a conical or round crown of foliage. White ash grows 60 to 100 feet tall with a trunk diameter of 4 feet, considerably larger than green ash trees. The leaves grow up to 12 inches long, usually with 7 leaflets that are 3 - 5 inches long. In the fall, the leaves turn yellow and then purple. This ash is also dioecious, and the male and female flowers are inconspicuous. The fruiting period is in September to November with fruits persisting to early winter. About 8 species of birds, mostly song birds, eat the seeds of the winged fruits. Many are the same as those that eat green ash seeds. This ash also is a larval host for caterpillars of 6 butterflies, some the same as green ash and some different. Both green and white ash trees provide cover and good nesting sites for birds. White ash grows well in sun, partial shade, or shade and in dry or moist acid soil.
Butternut (Juglans cinerea): The butternut tree, also called white walnut, reaches 40 – 80 feet tall with a trunk diameter of 1 – 2 feet. The leaves have 11 to 17 leaflets, each 3 - 4 inches long. The leaf size ranges from 15 to 30 inches. The yellow-green leaves turn yellow in fall. This tree is monoecious—the male and female flowers form on the same tree. Neither type of flower is conspicuous. The fruiting period is September to November. The fruits are oblong nuts, 1 to 1½ inches in diameter, that are covered with a sticky husk. About a dozen bird species eat the fruits. Most of them eat the meats of butternuts after they have been opened by squirrels or chipmunks or have split naturally. Butternut trees prefer sun and moist, neutral soil.
Mockernut hickory (Carya alba): The mockernut hickory grows 50 - 60 feet or more in height. The bark is rough with shallow ridges, but does not shed like the bark of shagbark hickory. The leaves are 9 – 14 inches long with 7 – 9 (and sometimes 5) leaflets about 6 inches long. The leaves turn bright golden yellow in fall. This tree is monoecious, and both the male flowers (catkins) and female flowers (spikes) are inconspicuous. The fruiting period is September to October, with fruit persisting to December. The round fruits, 1½ inches in diameter, have thick husks that encase the small nuts. Mockernut hickory prefers partial shade and acidic moist soil.
Shagbark hickory (Carya ovata): This tree grows 70 - 90 feet or more in height. It has shaggy bark that sheds. The leaves are 10 - 14 inches long, usually with 5 leaflets, but sometimes 7. In the autumn the leaves turn to yellow or gold. The male and female flowers are similar to those on the mockernut hickory. The fruiting period is September to October, with fruit persisting to December. The fruit, 1½ to 3 inches long, is nearly round and has a thick green husk covering the nut. This tree also provides cover and nesting sites for birds. It grows in sun, partial shade, and shade, and in dry or moist acidic soil.
About 20 bird species eat the nutmeats from mockernut and shagbark hickory trees, often after squirrels or other mammals have opened them or they have split naturally. Also, both mockernut and shagbark hickories are larval hosts for caterpillars of several butterflies and moths. Unfortunately, hickory trees have very long tap roots even when they are small so you may not be able to buy them at nurseries. If you know someone with hickory trees, you should be able to transplant them in the first year if you are very careful. Given that periodically oak trees do not produce any acorns, as is the case this year in our area, planting more nut trees certainly would help wildlife when the acorns are not around.


text:
Liverpool hold 'concrete discussions' over £72m target Jurgen Klopp 'adores'
LIVERPOOL face a wait to discover whether Nicolas Pepe is up for a move to Anfield.
Posted Wednesday, June 26, 2019 by Dailystar.co.uk
That is according to RMC Sport journalist Mohamed Bouhafsi, who claims Liverpool have held "very concrete discussions" with Lille over a potential deal.
Pepe is hot property after chipping in with 21 goal and 12 assists in all competitions last term.
Lille boss Christophe Galtier confirmed last month that the Ivory Coast international "will leave" in this transfer window.
Bouhafsi claims the 24-year-old is likely to delay a decision on his future until after the competition.
But Liverpool are not the only team interested in acquiring his services.
Bouhafsi told Get French Football News: "This is an €80m situation. So it is a situation that needs time and calm. What I can say is that there are very concrete discussions with Liverpool. Discussions that are not even denied by Lille, at Lille they don't deny the very concrete interest and discussions from and with Liverpool.
"Even Bayern Munich, I haven't checked in on this situation for a couple of days, but it is possible that other clubs have inserted themselves into the running.
Liverpool have held 'concrete discussions' over a swoop for Nicolas Pepe (Pic: GETTY)
"I know that one of my colleagues, Bilel Ghazi, who does an excellent job, who I want to congratulate because on top of that he is a very nice person at L'Équipe, speaks about Atletico Madrid and Inter Milan.
"I don't have any information on Atletico Madrid. For Inter Milan, I did speak about an unnamed 3rd club, following my exchanges on Nicolas Pepe and with Liverpool fans, and I think that this 3rd club could be Inter Milan. But I think that at €80m, this deal is too expensive for the Italian side.
"Then, I know that Jurgen Klopp adores Nicolas Pepe's profile, he brings a lot of speed and he is made to play in England, with quick transitions and an exceptional ability to counter-attack.
"Discussions have been had with Liverpool, who have a very profound interest.
"The other thing that I know is that Nicolas Pepe is at AFCON and wants a couple of days to make his decision.
"I don't know if you have been following but Liverpool is a club that often comes out to deny claims on transfers. Jürgen Klopp often talks about transfers and what isn't true (cites Lorenzo Insigne). Liverpool haven't denied (interest in Nicolas Pepe).
"I know that Bayern Munich are still following the situation closely, even if the Ivorian is not #1 on their shortlist. Their interest is still there like it was in winter.
"It is a situation that will decant in the coming days, or coming weeks, maybe just after AFCON. It needs time, because Nicolas Pepe is asking for time, and we have to respect the player's wishes, who wants to concentrate on his national team.
"And don't be surprised if other clubs dive into the race in the coming days, at Lille, I'm told that they are anticipating other Premier League clubs to get involved. It is not unthinkable."
Nicolas Pepe
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redpajama_set_name: RedPajamaCommonCrawl


Bittersweet Enchantment: BOOK BLITZ: Alterations by Stephanie Scott + Giveaway!
BOOK BLITZ: Alterations by Stephanie Scott + Giveaway!
for Alterations by Stephanie Scott! Be sure to enter the giveaway below to win a $20 Amazon GC!


SAN JOSE and SAN FRANCISCO, Calif. – Jan. 3, 2017 – KBM Workspace and Hogue, both premier Knoll dealerships headquartered in San Jose and San Francisco respectively, announced today that they have merged, resulting in a combined entity to be known as KBM-Hogue.
The merger creates an industry-leading, full-service office furniture dealership with operations in San Jose, San Francisco, and Sacramento, representing the largest Knoll dealership in Northern California. This transaction enables KBM-Hogue to leverage complementary areas of strength; including ground-breaking design, high-touch customer service, and flawless execution. The combined operations, expanded footprint, and economies of scale strengthens KBM-Hogue's market presence. Thus, enabling the company to achieve faster growth as a stronger, more competitive single company.
KBM-Hogue will be led by Vuckovich as CEO. His focus will be on guiding the company's growth, and continuing to develop its strategic vision. Under his leadership, KBM Workspace increased revenue by 6X since 2009.
Jonathan Gaber, of Hogue said, "I am excited about the possibilities that this merger brings to the entire KBM-Hogue team. As a larger and stronger company in a vibrant industry, KBM-Hogue will be able to offer our talented employees many paths to career success while taking the company to new heights." "This merger fulfills one of our original goals-to ensure and expand the Hogue model of success by combining two outstanding organizations that have a proven record of employee and client care.", shared David Boggs, of Hogue.
KBM Workspace, the premier Knoll dealer in Silicon Valley, was originally Kennedy Business Machines, founded in downtown San Jose in 1946. As a Knoll dealer from the beginning, KBM Workspace has been in the forefront of office furnishings design, from the days of typing pools and mahogany executive offices to the cubicles of the Silicon Valley startups to the mobile knowledge-workforce of the 21st century.
KBM has been celebrated in the San Jose/Silicon Valley Business Journal as one of Silicon Valley's 50 fastest private growing private companies. They were recognized by the San Jose Silicon Valley Chamber of Commerce as the Small Business of the Year in 2014.
Hogue, a premier Knoll dealership in San Francisco and Sacramento, was founded in 1974 by Wayne Hogue. Jonathan Gaber, President and David Boggs, CFO purchased the company in 1999. Since its inception, Hogue has continued its commitment to excellence through outstanding project management and customer service. Whether servicing a global law firm or a tech-start up, the teams consultative approach has fostered long-term relationships with their clients.
Knoll is a constellation of design-driven brands and people, working together with our clients to create inspired modern interiors. Our internationally recognized portfolio includes furniture, textiles, leathers, accessories, and architectural and acoustical elements brands. These brands - Knoll Office, KnollStudio, KnollTextiles, KnollExtra, Spinneybeck | FilzFelt, Edelman Leather, HOLLY HUNT, and DatesWeiser - reflect our commitment to modern design that meets the diverse requirements of high performance workplaces and luxury interiors. A recipient of the National Design Award for Corporate and Institutional Achievement from the Smithsonian`s Cooper-Hewitt, National Design Museum, Knoll is aligned with the U.S. Green Building Council and the Canadian Green Building Council and can help organizations achieve Leadership in Energy and Environmental Design (LEED) workplace certification. Knoll is the founding sponsor of the World Monuments Fund Modernism at Risk program.


text:
Poland, Hungary propose two-track way out of EU budget deadlock
By Alexandra Brzozowski and Zoran Radosavljevic | EURACTIV.com
Prime Ministers Mateusz Morawiecki and Viktor Orban. [Krystian Maj/KPRM]
Poland and Hungary reaffirmed on Thursday (26 October) their opposition to tying EU finds with the rule of law in member states and instead offered their own proposal for breaking the deadlock that is holding back the EU's €1.81 trillion seven-year budget and the recovery fund.
In the joint proposal, published after the two prime ministers met in Budapest, the two countries insisted they want to continue to limit any rule of law conditionality tied to the EU budget and that such a link should further be discussed.
The proposal is unlikely to go down well with the rest of the EU27, who are keen to unlock the badly needed EU funds but also safeguard basic EU values.
Hungary's Prime Minister Viktor Orban, standing alongside his Polish counterpart Mateusz Morawiecki, said in a press statement in Budapest that the current proposal on the table was unacceptable to Budapest and Warsaw, who will form a tandem in the debate after a joint veto, which Orban called a legitimate tool in the dispute.
"We are uniting our interests and arguments in the discussion, Hungary does not accept any arguments that would be unacceptable to Poland," Orban told reporters.
The declaration also includes a sentence that neither country – neither Poland nor Hungary – will accept the EU proposals without the consent of the other.
"The use of veto is the baseline scenario. We are faced with a mechanism that, through its arbitrariness, would lead to the fragmentation of the EU. This mechanism is the regulation on the so-called rule of law," Morawiecki said.
"This is a bad solution and it may collapse the EU in the future – argued the Polish head of government," he said.
"Conditionality formulated in this way is a bait for any country," Morawiecki said. "We do not need a Union of two contradictory interpretations, we don't need a two-speed Union, which is why we will defend the sovereignty of the treaties," he added, saying that Poland and Hungary would act for the good of the entire bloc.
According to the document, both countries suggest a "two-track process", which is meant to facilitate the speedy adoption of the EU 2021-2027 budget, but might also involve changes to EU treaties.
The EU should drop the rule-of-law conditionality for now to speed the flow of billions in aid to countries suffering record economic downturns amid the COVID-19 pandemic and to approve the 2021-2027 budget, both leaders said.
The EU could return later to how it wants to enforce democratic standards, though that would require amending its treaty, which requires a unanimous decision, they said.
"On the one hand, to limit the scope of any budgetary conditionality to the protection of the financial interests of the Union" according to what member states agreed in the July EU summit.
On the other, the statement said, the European Council should discuss "whether a link between the rule of law and the financial interests in the Union should be established".
For the adoption of the budget and the reconstruction plan, unanimity is required.
"We gave ourselves and the German presidency time to try to find a compromise between the approach of various member states in the context of the EU budget by the end of this year," Orban said.
The new proposal by Warsaw and Budapest is likely to put them straight on a collision course with frugal net contributors like the Netherlands, which advocated for the current law-of-rule provision as the bare minimum needed to protect the bloc's funding and most basic values.
If no consensus is reached by the end of the year, the EU will act on a provisional budget.
This means that only funds resulting from previous commitments will be disbursed, such as subsidies for farmers or funds for the maintenance of the EU administration.
Funds for new investments will be frozen, including infrastructure and a separate fund for reconstruction after the COVID-19 pandemic.
Pressure mounts on Hungary, Poland to lift EU budget veto
In today's edition of the Capitals, find out more about Poland's main figure in opposing the government's judicial reforms has, Judge Igor Tuleya, has lost his immunity from prosecution, Spain's measures to 'save Christmas', and so much more.
[Edited by Zoran Radosavljevic]
EU budget


text:
Intriguing Encounters
I have met a number of people in my life. Among them are people
who stir praise, joy, inspiration, controversy and even hatred. Below
are some of these people. Regardless of the emotions they provoke in
you, the fact remains that they are significant on some social, political,
professional or artistic level. These are among the most intriguing
people I have met. I hope to meet more.
Nigerian writer Chinua Achebe and Ghanian writer Ama Ata Aidoo
I first met Achebe in 1992 in Madison, Wisconsin, USA and again in 2008
in Washington DC where this photo was taken at a gathering
celebrating the 50th Year Anniversary of his novel, Things Fall Apart. I
also met Aidoo at this gathering. But my first meeting with her was in
the early 1980s at a literary conference at the University of Calabar,
Nigeria.
South African Poet and anti-apartheid activist,, Dennis Brutus
This photo was taken at a literary conference at the University of
Calabar, Nigeria, in the early 1980s. Brutus is third from left. I am fifth
from left.
Olusegun Obasanjo, former Nigerian President and Military Head-of-State
Obasanjo is perhaps one of Nigeria's most controversial political figures and the
only man to rule the country three times, first as military dictator and twice as
elected president. This picture was taken in 2001. In my few meetings with
Obasanjo, he has been quite gracious.
Somali writer Nuruddin Farah and Batswana writer Bessie Head
I met both writers in the early 1980s at a literary conference at the
University of Calabar, Nigeria. Though Head is often described as a
Batswana writer, she was born in South Africa.
Nigerian writers Gabriel Okara and James Ene Henshaw
University of Calabar, Nigeria.
Festus Mogae, former President of Botswana
I met him in 2008 in Gabarone, Botswana. He was
the third president of the country.
Nigerian writer and Nobel Laureate, Wole Soyinka
This photo was taken around 2003 in Abuja, Nigeria at
an even celebrating the author. Soyinka, in grey hair,
is seated. I am first from left. Moremi, Soyinka's
daughter, is second from left.
Nigerian writer, Chimamanda Ngozi Adichie
This not-very-clear photo was taken in 2013 in
Nairobi, Kenya. Adichie is in the middle while
my wife, Chinwe, is first from left.
Nigerian writers Flora Nwapa and Cyprian Ekwensi
Nwapa is second from left while Ekwensi is third from left. Nwapa's novel, Efuru (1966) was
the first novel by a sub-Saharan African woman to be published in the English language. First
from left is Charles Nnolim, Professor of English. This photo was taken in the early 1980s at a
literary conference at the University of Calabar, Nigeria.


text:
Latest ME/CFS Research
Reduced HRV (heart rate variability) predicts poor sleep quality in CFS
Thread starter ahimsa
ahimsa_pdx on twitter
This was posted on the co-cure mailing list recently:
Exp Brain Res. 2010 May 26. [Epub ahead of print]
'Reduced heart rate variability predicts poor sleep quality in a
case-control study of chronic fatigue syndrome.'
Burton AR, Rahman K, Kadota Y, Lloyd A, Vollmer-Conna U.
School of Psychiatry, University of NSW, Sydney, Australia.
Parasympathetic function is important in the induction and maintenance
of sleep. We examined whether nocturnal vagal modulation of heart rate
is related to the poor sleep quality commonly reported in chronic
fatigue syndrome (CFS). Heart rate (HR, as R-R intervals) was
continuously monitored during sleep in 20 patients with CFS and 20
matched control subjects. Questionnaires assessed demographic
information, symptoms, functional impairment, and subjective sleep
quality. CFS was associated with more sleep problems in general and
poorer subjective sleep quality on the study night (all p < 0.003),
and reports of repeated awakening during the night were 7 times more
likely compared to healthy subjects (p = 0.017). Time and
frequency-domain parameters of HR variability during sleep were
significantly lower in patients with CFS (all p < 0.006). Multiple
regression analyses revealed that heart rate variability (HRV)
parameters were the best predictors of subjective sleep measures. This
study identified significant reductions in vagal modulation of heart
rate during sleep in CFS. Low HRV strongly predicted sleep
quality-suggesting a pervasive state of nocturnal sympathetic
hypervigilance in CFS.
I was intrigued by this abstract because frequent awakening (up to 10-12 times a night) is my biggest sleep problem. So I searched for reduced HRV and found this other study from 2007:
http://www.cfids-cab.org/rc/Boneva.pdf
Anyone out there want to explain a bit more about what causes reduced HRV and/or suggested treatments? In the little bit of searching that I've done I've seen it linked to everything from depression to congestive heart failure. So it's a bit difficult for me to understand how to view these studies.
I'm hoping someone with more medical knowledge will be able to shed some light on this study as well as any other sleep problems related to autonomic dysfunction/dysregulation.
ahimsa said:
Sorry to be awkward but just to point out to everyone that the Boneva study (but not the initial study) is an empiric criteria (Reeves, 2005) study. It's the Wichita 2-day study cohort which is not as "diluted" as the Georgian cohort but still 10 (most likely - a maximum of 16 anyway but most likely 10) of the 43 CFS cases satisfied the Fukuda definition.
Ill since 1989 said:
Sorry to be awkward ...
Please don't feel awkward on my account - I want to know the details behind these studies. I appreciate the additional information. Thank you!
I hope there are others out there who can comment on the general concept of reduced HRV and what it might mean in Fukuda and/or CCC ME/CFS patients (or even in heart failure patients, elderly, etc.).
Sofa, UK
"a pervasive state of nocturnal sympathetic hypervigilance"
From my own experience I can say with confidence that permanent disruption of sleep (failure of sleep) over a long period of time can cause very many of the symptoms of CFS, possibly even enough on its own to cause symptoms approaching a Fukuda but probably not CCC definition. Fatigue, muscle weakness, aches and pains, loss of short term memory and other cogntive impairnents, vulnerability to infection, problems with digestion, (not to mention anxiety and depression), all of these can (IMO) result solely from "a pervasive state of nocturnal hypervigilance" - ie the body never gets to shut down at night. So I reckon that prolonged sleep disturbance - especially if unrecognised - on its own might get you a diagnosis of CFS, with weak criteria. But the more severe neurological and immune symptoms, such as are those listed in the CCC, are more characteristic of 'ME' than 'CFS' (whatever ME and CFS may be...) and I don't know whether they could result from disturbance of sleep / loss of deep sleep alone.
Anyway this is a roundabout way of saying that patients with Reeves/Oxford style definitions and even some Fukuda patients could be found who fit the criteria purely because of sleep disturbance. So the context for this research might be that one subcluster of the "CFS" wastebasket diagnosis is those who have prolonged sleep disturbance, for whatever reason.
The reduced HRV then...the research is just saying there's a correlation between reduced HRV and sleep quality in this grouping patients...I'm not clear which is more likely to cause the other - or another association suspected...and wonder whether there's any such correlation in other patients with sleep apnea...but it seems their conclusion is that this suggests that "sympathetic hypervigilance" is going on in CFS sleep disturbance.
TH2 hyperstimulation (as result of active XMRV infection or otherwise), and over-reaction to environmental triggers, sounds like it could cause "sympathetic hypervigilance" - sounds a good description of what I've had going on anyway.
IamME
Too sick for an identity
In addition to what IllSince1989 says, Andrew Lloyd is a fully fledged psychologiser (he was one of the first off the starting block to rubbish XMRV and spread rumours about the WPIs research) -- this is the School of Psychiatry after all. The notion that reduced HRV and sleep dysfunction automatically = nocturnal hypervigilence is stupid and a complete leap of perverse logic. Even if it *was* true, "hypervigilence" would not be important because it's not the cause of ME, unlike a differential diagnosis. Mark, bad insomnia cannot cause all the symptoms/signs of ME. What they're trying to do is make this finding fit a stress hypothethis, an affective disorder or PTSD-like illness which they believe can be magicked away with CBT/GET by using a correlation/causation fallacy. Nothing must get in the way of that message.
http://www.abc.net.au/rn/allinthemind/stories/2007/1945419.htm
What the psychiatrists would call cognitive behavioural therapy. And that basically is a combination of approaches to manage symptoms, say, pain relief for instance [No - it's not actually]; approaches to give people sensible advice about the issue of rest versus exercise in relation to the fatigue syndrome. Managing the sleep/wake cycle if it's gone off the rails, managing mood disorder if it's present, and finally a structured, gradually incrementing graded physical exercise program.
http://www.mja.com.au/public/issues/172_10_150500/lloyd/lloyd.html
In the absence of a clear understanding of the underlying pathophysiology, CFS is best described as an illness rather than a disease.4 Illness is a subjective state of suffering -- physical, psychological and social [...] In disorders associated with broad disturbances of central nervous system function there is commonly an interplay between cultural, personal and biomedical factors. Thus, it is not surprising that cognitive-behavioural approaches have shown benefit in clinical trials [...]
A recent evaluation of patients with chronic fatigue in Hong Kong may provide an important insight for our "Western" medical practice.7 For these patients the notion of having a "medical" versus "psychiatric", or "biomedical" versus "psychosocial", cause of their illness made little sense. Their perception was that, while they were clearly unwell, the potential causes of that suffering could lie across a broad domain of personal, social or medical factors. If Australian patients and their doctors could rediscover this basic concept, and could also accept prolonged fatigue as a legitimate illness experience, there would be no need for the polarisation of aetiological models (and political views) that has become characteristic of medical practice in relation to CFS in the USA and UK. This unnecessary polarisation is intellectually shallow and harmful to patients.
To build an effective therapeutic alliance, doctors should endeavour to maximise non-specific treatment effects [...] The cornerstones of good management include providing information about the illness and its natural history; empirical treatment of disturbances of mood and sleep which commonly co-occur in CFS; and encouraging a rehabilitative approach to the illness, including graded physical activity as well as psychological and social support
I think he used to be more pro-biomedical but has become incresingly obsessed with GET, referring to "fatigue states" and this sort of psychogibberish sophistry.
Agree with that.
Ian Hickie, an Australian psychiatrist who sometimes works with Lloyd on CFS stuff, is another to watch out for. He has been very influential both within Aust and internationally (works with Reeves, White, Wessely, et al, you get the idea, was co-author on the CDC Fukuda definition, & the Australian Clinical Guidelines, and IIRC he gave us the useless and dangerous SPHERE 'test' for somatising). But he has largely managed to escape serious scrutiny so far.
Do a PubMed search for (Hickie IB) AND (Lloyd AR)
anciendaze
Heart Rate Variability as a measure of cardiac function
There were studies back in the late 1980's which surprised many cardiologists by showing reduced heart rate variability was an indicator of declining cardiac health. This came out of studies on cardiac dynamics using fairly advanced mathematical theories unfamiliar to most cardiologists. Where a natural assumption that variability increased as you approached a breakdown was wrong was in the misunderstanding of adaptability to changing conditions. Reduced variability meant that feedback in response to changing conditions was not taking place. There is plenty of reason to associate poor cardiac health with poor sleep.
Likes: Float
I agree that Lloyd appears to have become more behaviorist but be careful about damning a study because of its authors. HRV readings are probably the most consistently abnormal readings in CFS research - which is really saying something.
Lloyd's big research project the Dubbo studies - had nothing at all to do with behavior - it took a straight shot at the immune system to try and explain why people were coming down with CFS after an infection. I'd be cautious of categorizing Lloyd too narrowly - yes he does believe behavioral therapies are helpful but he's also been very interested in immune functioning and pathogens as well as gene expression.
Cort said:
he's also been very interested in immune functioning and pathogens as well as gene expression.
I'm not convinced he's interesting in finding pathogens and using anti-viral and anti-microbial treatments.
Here's his other recent contribution to the literature - he was the lead author and corresponding author for this letter to Science:
Science 14 May 2010:
Vol. 328. no. 5980, p. 825
DOI: 10.1126/science.1183706
Prev | Table of Contents | Next
Technical Comments
Comment on "Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome"
Andrew Lloyd,1 Peter White,2 Simon Wessely,3 Michael Sharpe,4 Dedra Buchwald5
Lombardi et al. (Reports, 23 October 2009, p. 585) reported a significant association between the human retrovirus XMRV and chronic fatigue syndrome (CFS). However, the cases with CFS and the control subjects in their study are poorly described and unlikely to be representative. Independent replication is a critical first step before accepting the validity of this finding.
1 Centre for Infection and Inflammation Research, University of New South Wales, Sydney, Australia 2052.
2 Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine, Queen Mary University of London, London, UK.
3 Department of Psychological Medicine, Institute of Psychiatry, Kings College London, UK.
4 School of Molecular and Clinical Medicine, University of Edinburgh, UK.
5 Center for Clinical and Epidemiological Research, University of Washington, Seattle, WA 98101, USA.
* To whom correspondence should be addressed. E-mail: a.lloyd@unsw.edu.au
The finding of a significant association between xenotropic murine leukemia virusrelated virus (XMRV) and the enigmatic clinical illness, chronic fatigue syndrome (CFS), has the potential to revise our understanding of the pathogenesis of this condition and raise serious public health concerns (1). It is unusual to find such a strong association between an infectious agent and a well-defined chronic disease, much less an illness like CFS. As such, critical evaluation of the results is paramount. Experienced CFS researchers will remember the 1991 "discovery" of an HTLV-2like retrovirus in CFS (2), which subsequent studies failed to replicate (36).
For reliable results, clearly defined cases should be compared to a control group similar in all aspects other than the disease. The 101 patients studied in (1) were "patients fulfilling the 1994 CDC Fukuda criteria for chronic fatigue syndrome and the 2003 Canadian Consensus Criteria for chronic fatigue syndrome/myalgic encephalitis (CFS/ME) and presenting with severe disability" [supporting online material for (1)], but the latter requires physical signs precluded in the former. The patients were selected, in part, with immunologic perturbations such as in RNase L pathways, yet there are no biomarkers that have demonstrated reliability in affirming the diagnosis of CFS (7). Lombardi et al. (1) provided no description of demographics, illness duration, pattern of onset, or evaluation for exclusionary medical and psychiatric conditions. Likewise, the characteristics of the controls, and details of collection, handling, and storage of specimens, are not described. It is therefore impossible to critically evaluate the findings.
CFS is likely to arise from complex genes-x-environment risk factors, making a simple causative link between XMRV and CFS unlikely. Even if confirmed, further research will be needed to demonstrate causality. In relation to prostate cancer, with which a comparable association with XMRV was reported (8), negative replication studies are mounting (9). Similarly, three negative replication studies in well-characterized cases of CFS have now been published (1012). This outcome serves as a cogent reminder of the need for independent replication before findings such as this can be accepted.
1. V. C. Lombardi et al., Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome. Science 326, 585 (2009).
2. E. DeFreitas et al., Retroviral sequences related to human T-lymphotropic virus type II in patients with chronic fatigue immune dysfunction syndrome. Proc. Natl. Acad. Sci. U.S.A. 88, 2922 (1991).
3. J. W. Gow et al., Search for retrovirus in the chronic fatigue syndrome. J. Clin. Pathol. 45, 1058 (1992).
4. M. Honda et al., Japanese patients with chronic fatigue syndrome are negative for known retrovirus infections. Microbiol. Immunol. 37, 779 (1993).
5. A. S. Khan et al., Assessment of a retrovirus sequence and other possible risk factors for the chronic fatigue syndrome in adults. Ann. Intern. Med. 118, 241 (1993).
6. W. Heneine et al., Lack of evidence for infection with known human and animal retroviruses in patients with chronic fatigue syndrome. Clin. Infect. Dis. 18 (suppl. 1), S121 (1994).
7. M. Lyall, M. Peakman, S. Wessely, A systematic review and critical evaluation of the immunology of chronic fatigue syndrome. J. Psychosom. Res. 55, 79 (2003).
8. R. Schlaberg, D. J. Choe, K. R. Brown, H. M. Thaker, I. R. Singh, XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors. Proc. Natl. Acad. Sci. U.S.A. 106, 16351 (2009).
9. O. Hohn et al., Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients. Retrovirology 6, 92 (2009).
10. O. Erlwein et al., Failure to detect the novel retrovirus XMRV in chronic fatigue syndrome. PLoS ONE 5, e8519 (2010).
11. H. C. Groom et al., Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome. Retrovirology 7, 10 (2010).
12. F. J. M. van Kuppeveld et al., Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort. BMJ 340, c1018 (2010).
13. M.S. has been paid by insurers for independent advice on medical claims that might include CFS. He has also been paid by lawyers for independent advice on litigation that might include CFS.
Received for publication 22 October 2009. Accepted for publication 18 April 2010.
gracenote
All shall be well . . .
From the full text of the article.
Whether reduced HRV during sleep is linked to the common experience of sleep problems and unrefreshing sleep in CFS has not been explored. The objective of this study is to examine this link, hypothesising that diminished HRV during sleep is associated with poorer sleep quality in subjects with CFS. The effects of relevant covariates of sleep quality including levels of current stress, and psychological distress were also considered.
The 30-item perceived stress questionnaire (PSQ) was used to assess current levels of stress (Levenstein etal. 1993) and common symptoms of psychological distress were reported via the Kessler 10 (K10; Kessler etal. 2002). Functional impairment was assessed by The Brief Disability Questionnaire (BDQ; Von KorV etal. 1996). The 34-item Somatic and Psychological Health Report (SPHERE; Hickie etal. 2001) was used to assess a wide range of physical and psychological symptoms.
The low levels of nocturnal HRV found in our study, are suggestive of a pervasive state of sympathetic hypervigilanceone which is consistent with previous reports of hypoactivity in the prefrontal cortex in this population.
This doesn't appear to me to be a study to determine any kind of medical causation of sleep difficulties in CFS. Why would they even choose to use assessments of psychological health in a study such as this? This is more of the same in my opinion.
I think they would have gotten more useful information by comparing CFS with other medical conditions that show low HRV. I found this on Wiki (not up to doing a better search at the moment):
A range of other outcomes/conditions may also be associated with modified (usually lower) HRV, including congestive heart failure, diabetic neuropathy, depression post-cardiac transplant, susceptibility to SIDS and poor survival in premature babies.
Ironically due to really bad sleep of late (worse than the usual, I mean), I am actually awake in the AM (which has not happened in a long time) & as a result am not at all alert (wouldn't hypervigilance make me more alert?!) ....I am, in fact quite foggy, so my logic may be off, but this occurred to me.........
While this study focused on nocturnal HRV, in general reduced heart rate variability does not just mean that the resting heart rate is too high (as would be the case with hypervigilance) but it also measn that the max heart rate may not be as high, either
..... studies have shown that ME/CFS patients cannot get their heart rates up very high during exercise (one of the differences that has been cited by actual good biomedical research that differentiates ME/CFS from depression).....so if you turn this study on its head, using their logic, then it would seem that the inability to raise max heart rate much at all would indicate just the opposite
I have actually recently been paying attention to my own heart rate variabilty, so the timing of this article is kind of interesting......and I noticed that pre-ME/CFS my heart rate could vary (from its lowest immediately upon waking to its highest immediately after exercise) by more than 130 points, and now, when I manage to get any exercise (granted not at the same intensity, and not often, but I do still manage to swim some or do some other exercise on occassion), my heart rate, at best varies less than 30 points from waking to post exertion (not only does that not fit with what would happen if this were depression, but it also does not fit with what would happen if I were just out of shape)....and though my resting heart rate has increased a bit, the reduced variability is for the most part on the other end of the spectrum (ocurring after any exertion)
Tammie said:
Interesting although just in case anyone is confused, Heart Rate Variability, has a specific definition e.g. http://en.wikipedia.org/wiki/Heart_rate_variability
12 out of the 20 were from the Dubbo study (RRV: N = 7; EBV: N = 4; Coxiella burnetii: N = 1), the other 8 from Dr. Lloyd's practice.
Thought this was interesting:
Heart rate variability can be affected by a number of
mechanisms. For example, it can be directly affected by
levels of activity—it can be increased as a result of exercise
training (Levy et al. 1998; Malfatto et al. 1996). Relating to
this, previous authors have speculated that the reduced
HRV seen in CFS may be a result of cardiovascular deconditioning
(Freeman and Komaroff 1997; De Lorenzo et al.
1998). In the current study, the patients with CFS were
matched for age, BMI and activity, and additionally there
was not substantive between-group diVerence in resting
HR. It is therefore unlikely that cardiac deconditioning was
a determinant of the documented differences in HRV.
gracenote said:
After finding that low HRV is the main factor, they then speculate this might caused by hypoactivity in the prefrontal cortex:
Hypoactivity in the prefrontal circuits
and a lack of inhibitory neural processes typically characterise
psychopathological states, including anxiety, depression,
and post-traumatic stress disorder (Thayer and
Friedman 2004, Thayer 2006).
They don't tell us of the "physical" conditions where low HRV is an issue.
I think how they link hypoactivity in the prefrontal cortex to CFS is weak:
There is some evidence that individuals with CFS may
exhibit anatomical and functional alterations in the prefrontal
cortex—as evidenced by lowered cerebral activity in the
dorsolateral and dorsomedial prefrontal cortices during
fatigue provoking tasks (Caseras et al. 2008) and a bilateral
reduction of grey-matter volume in the prefrontal cortex
(Okada et al. 2004; De Lange et al. 2009). However, dissection
of the mechanisms involved in this process need to
be interpreted with caution: it is not known whether the
changes seen in the prefrontal cortex in CFS are a symptom
or a cause of CFS (De Lange et al. 2009). Nevertheless,
since the role of the prefrontal cortex is essential in active
tonic inhibition of sympathoexcitatory threat circuits, such
alterations in the prefrontal cortex seen in CFS subjects
could be expected to lead to a decrease in vagal drive
defaulting to a sympathetically driven system.
They then suggest other forms of dysautonomia seen in CFS could be due to this
We speculate that changes in the prefrontal cortex seen
in CFS may not only contribute to the reduction of tonic
vagal activity as seen in our study, but may also be manifested
in other forms of dysautonomia seen in CFS.
We recently have research which looks at this a bit differently:
"Impaired cardiovascular response to standing in Chronic Fatigue Syndrome"
Full text at: http://www.imet.ie/imet_documents/Impaired CV responses to standing in CFS.pdf
start of discussion section of that paper:
We have demonstrated that the skeletal muscle bioenergetic abnormality recently described in patients with CFS [1] associates with a similar cardiac bioenergetic abnormality. This impairment is associated with an increase in cardiac contractility on standing (i.e. the heart has to work harder for the same degree of physiological stress), the severity of which associates with symptoms on standing in those with CFS.


text:
Court decides in favor of EPA in Clean Water Act storm water decision
WEBWIRE – Thursday, August 16, 2007
The U.S. Environmental Protection Agency Region 8 announced today that a federal environmental administrative law judge has ruled for EPA in a clean water enforcement case against the Service Oil, Inc., a gasoline and diesel fuel retailer headquartered in West Fargo, N.D.
In an initial decision, Chief Administrative Law Judge Susan L. Biro ordered the company to pay a civil penalty of $35,640. EPA had sought a penalty of $40,000. Service Oil has 30 days from Aug. 3, 2007 to appeal.
Judge Biro found that Service Oil failed to acquire an applicable discharge permit for construction activities and discharged pollutants without a permit, both in violation of the federal Clean Water Act.
"Region 8 resolves most of its enforcement actions through negotiation," said Michael Risner, Acting Deputy Assistant Regional Administrator for EPA's Denver headquarters. "When necessary, we will pursue a formal hearing to ensure that enterprises are meeting their environmental responsibilities. We hope that the judge's decision will encourage other companies to comply with the law."
David Janik, Region 8 Supervisory Enforcement Attorney, said, "It is gratifying that Judge Biro upheld our complaint in the Service Oil case and validated the hard work of our inspectors and case team"
The case stems from an EPA inspection in 2002.


text:
TREASURES BOX
YOUNG MUSICIANS on WORLD STAGES
ORFF-SCHULWERK
TEVİTÖL MUSIC DEPARTMENT
REFLECTIONS by PEKINELS
Bartók And Painting
|In Reflections by Pekinels
|By admin
Hearing colours. Seeing sounds by Güher & Süher Pekinel
At the beginning of the 20th century, the tonal basis of classical music – "the tyranny of the major and minor modes", as Stravinsky described it – changed dramatically. The development of serialism and the introduction of twelve-note technique ushered in a new era.
At that time, Béla Bartók, a music ethnologist with a strong affinity for the German tradition, developed a synthesis all of his own: a style of composition that united elements of folk music, classicism and modernism. By combining rhythmically and melodically asymmetrical chromatic harmonies, he was able to develop a complex musical language that found its expression in the Concerto for two pianos, percussion and orchestra written in 1940. With its inner logic, its lucidity and its expressiveness, the work has almost classical features. It is characterised by a distinct linear polyphony that results from the different pitches of the solo instruments. Sophisticated polyrhythms and systematic shifts of emphasis create tone colour melodies which – as also in Stravinsky – produce unfamiliar rhythms and melodies. Bartók's piano concertos include consistent use of percussion as melody instruments, which additionally enriches the musical language. As one of the co-founders of ethnomusicology, Bartók, together with Zoltán Kodály, collected the folk songs of different cultures and researched into their peculiarities and similarities. For example he visited towns and villages in Anatolia accompanied by the Turkish composer Adnan Saygun in 1936 and selected 67 songs which he later took up again in his works. Paul Hindemith also made a valuable contribution to this archive, which is now part of the Bartók Museum in Osmaniye.
The painter and ethnologist Wassily Kandinsky also used folk elements as a basis for his early works. As his paintings became increasingly abstract, he developed a form of synaesthesia which allowed him to work in non-objectivity. The example he followed here was that of music. His aim was to hear colours and see sounds. For this purpose, he arranged colour sounds into colour symphonies. Other artists, including Klee, Mondrian, Miró, Matisse and Jawlensky, took up this compositional technique and implemented it individually in their work. Like Berg, Webern, Reger, Debussy, the Russian avant-garde or the French expressionists, Bartók too followed this development and these synergies with great interest. In particular the paintings of Mondrian and Kandinsky confirmed his belief that "ostensibly simple forms of drawing can be products of a very complex creative process". His writings, particularly the Harvard Lectures "Revolution and Evolution in Art" (1943) convey these thoughts on music theory in a very understandable manner.
Personal motivation
Between 1970 and 1985, we were driven by an inner need to spend our free time painting and studying the abstract expressionism associated with Kandinsky and were inspired by his two most important writings "Concerning the Spiritual in Art" (1911) and "Point and Line to Plane" (1926). While we were living in Munich, we visited exhibitions and attended lectures at the Academy of Art and the Lenbachhaus gallery (Blauer Reiter collection). This enabled us to renew and intensify our inner imaginative faculties both figuratively and musically. Our enthusiasm for Bartók and the recording of his Sonata for Two Pianos and Percussion for Teldec/Warner stem from this period. Our paintings "The Sonata" and "Harmony of Contradictions" were also produced at that time.
IKSV-Poster
Two paintings by Güher & Süher Pekinel integradted as a poster for the 42nd Istanbul Culture and Arts Foundation (IKSV) Music Festival.
© 2019 Copyright – Pekinels Official Website. Güher & Süher Pekinel. All Rights Reserved.
Design | Badbaz Digital Communication


In Maryland, there are 7 common reasons for suspended license. If you are charged with driving on a suspended license in Maryland, contact attorney Randolph Rice at (410) 694-7291 or email him for immediate legal help.
Points. You have received too many points on your Maryland driving record and the MVA has suspended your license. 8-11 points and the MVA will send you a suspension letter.
Violation of License Restriction. You weren't suppose to do something while driving and you did it and the MVA has suspended your license.
Medical Advisory Board. The Medical Advisory Board has determine you are unfit for a medical reason, that you are unfit to drive.
Fail to Pay a Fine for a previous ticket. You failed to pay an old traffic ticket and the Court notified the MVA and the MVA suspended your license. Go pay he ticket right now and the MVA will life the suspension. Make sure you ask for a "trial" when you pay that old ticket.
Fail to pay Child Support. You failed to pay child support, the child support office notified the MVA and the MVA suspended your license.
Failed to take a test during a DUI/DWI investigation. You were pulled over for DUI (driving while under the influence of alcohol) or DWI (driving while impaired) and you refused to take the breath or blood test, the MVA may suspend your license.
Too many DUI or DWI convictions. You have too many DUI or DWI convictions and the MVA will suspend your driver's license and privilege to drive.
There are other less common reasons for suspended license in Maryland, but these 7 are the most common.
What do you do know. If you can fix one of these Maryland 7 reasons for suspended license, do it as soon after you've been pulled over and charged with driving on a suspended license.
But you still have to go to Court. Call our office at (410) 694-7291, ask for attorney Randolph Rice and let him defend you in Court. His offers free consultations and payment plans for his services. He may be able get you out of the charges if you didn't know your license was suspended.
Call the Law Offices of G. Randolph Rice, Jr., LLC, at (410) 694-7291 for immediate legal help.


MONTEVIDEO (REUTERS) - Uruguay will head to the World Cup on a winning note after beating Uzbekistan 3-0 in a chilly warm-up in front of their own fans on Thursday (June 7).
The win, against a side ranked 81 places below them at 95th in the world, was the third in a row for the South Americans and they have lost just once in their last nine games.
Uruguay got the breakthrough after 31 minutes when Giorgian De Arrascaeta fired home from 15 metres following good work from Edinson Cavani and Luis Suarez.
Suarez doubled their lead eight minutes into the second half when he slotted home a penalty and Jose Maria Gimenez headed home a corner in 72 minutes to make it 3-0.
Uzbekistan were then reduced to 10 men when Komilov Akromjon was sent off.
Uruguay, who won the World Cup in 1930 and 1950, kick off their World Cup campaign on June 15 against Egypt, play Saudi Arabia five days later, before rounding out their Group A fixtures against hosts Russia.


Spiralite Gemshells are extraordinary agatized spiral seashell fossils from India. This interesting stone is a bridge between the mineral and animal worlds which makes it easier for one to access crystal energies. They are believed to store some memory of ancient times of life on Earth. These can be great stones for channelers, healers, medical seers, and prophetic visionaries. Also, this can be ideal for those who are interested in telepathic communication with the sea creatures such as whales and dolphins.
Spiralite Gemshells have strong vibrations that promote longevity and bodily stamina which can help one recover from illness. It is also believed to support evolutions of DNA and preservation of life.


text:
UFC Fight Night 138's Anthony Smith: Changing of the Guard
Believe It or Not, The UFC Needs Jon Jones
Mike Pendleton
Bellator 131: Tito vs. Bonnar Preview and Predictions
Sal DeRose
Kunlun Fight 77 Results: Zuev, Kiria, Toutouh and Xingli Advance
UFC Fight Night 139: Korean Zombie vs. Rodriguez Weigh-in Results
Bellator 199: Bader vs. King Mo Weigh-in Video and Results
Invicta FC 12: Kankaanpää vs. Souza Weigh-in Photo Gallery
MMA Ratings Podcast Episode 72: UFC on Fox 27 and Bellator 193 Preview
Schwan Humes
Tagged Los Angeles
GLORY 52: Los Angeles Fight Night Photo Gallery
On Saturday, March 31, GLORY Kickboxing visited Los Angeles for its 52nd event. The promotion touched down at the Pacific Room at the Long Beach Arena. In the night's main event, reigning featherweight champ...
Robin van Roosmalen vs. Kevin VanNostrand Headlines GLORY 52 in Los Angeles on March 31
GLORY Kickboxing is returning to Los Angeles. The promotion has announced that it will visit the Pacific Room at the Long Beach Arena on Saturday, March 31 for its 52nd event. In the night's main event, f...
GLORY 37 Los Angeles Results: Wilnis Retains, Kongolo Captures Tournament
Rob Young
On Friday, Jan. 20, GLORY kickboxing returned to California for GLORY 37: Los Angeles. In the night's main event, newly crowned middleweight champion Jason Wilnis put his belt on the line against recent tour...
GLORY 37 Los Angeles Weigh-in Results: Wilnis, Adesanya Hit the Mark; van Roosmalen Stripped of Title
On Friday, Jan. 20, GLORY kickboxing returns to California for GLORY 37: Los Angeles. In the night's main event, newly crowned middleweight champion Jason Wilnis puts his belt on the line against recent tour...
GLORY 37: Los Angeles Preview and Predictions
GLORY 37: Los Angeles and SuperFight Series Finalized
The fight cards for GLORY's return to Los Angeles have been revealed. In the night's main event, newly-crowned middleweight champion Jason Wilnis puts his belt on the line against recent tournament winner Is...
Robin van Roosmalen vs. Matt Embree Headlines GLORY 37: Los Angeles
The headlining bout for GLORY's return to Los Angeles has been revealed. Newly-crowned featherweight champion Robin van Roosmalen will put his belt on the line against Canadian Matt Embree in the night's mai...
GLORY 30 Results: Marcus Defends, Abraham Claims Tournament
GLORY kickboxing returned to the United States on Friday, May 13, for GLORY 30: Los Angeles. The middleweight division was in the spotlight with four of the world's top six 187-pound kickboxers fighting at the ...
GLORY 30: Los Angeles Weigh-in Results
GLORY kickboxing returns to the United States on Friday, May 13, for GLORY 30: Los Angeles. The world's consensus top kickboxing promotion travels across the Atlantic after two successful events in Europe. The ...


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