The lab of Rice University synthetic organic chemist K.C. Nicolaou has reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule previously claimed to kill leukemic cancer cells.
The researchers said their work sets the stage for large-scale synthesis of the cytotoxic agent, a lipid found in nearly all animal tissues, and related compounds that can be produced as potential agents to treat certain types of cancer.
The report by Nicolaou and his colleagues on the streamlined total synthesis appeared in Chemistry – A European Journal.
The Nicolaou lab specializes in the synthesis of therapeutic molecules found in nature, but in amounts too small for thorough biological evaluation or clinical use. Since joining Rice and setting up at the BioScience Research Collaborative in 2013, Nicolaou and his team have achieved the synthesis of several cancer-fighting molecules. Nicolaou is best known for the total synthesis of paclitaxel, a drug commonly used to treat a number of cancers.
The prostaglandin the Nicolaou lab synthesized had been isolated in 2011 as a secondary metabolite formed from eicosapentaenoic acid that is found primarily in fish oil.
The Nicolaou lab reported the first total synthesis of the molecule in 2014. That allowed them to confirm its structure. Now the lab has established techniques to develop related disease-fighting compounds and ramp up bulk production if necessary. Several such derivatives under consideration as preclinical drug candidates were detailed in a second paper by the lab this month.
The lab reported that total synthesis of the natural product now requires only six steps from commercially available starting materials. Such a concise and efficient route is highly desirable for the synthesis of preclinical drug candidates and drugs.
In the second paper, the Nicolaou lab identified a macrolactone derivative, formed by joining two functional groups together, as a promising chemotherapy agent to fight a variety of cancers. That publication in the Journal of the American Chemical Society described the synthesis of dozens of prostaglandin derivatives. Nicolaou said the National Institutes of Health's National Cancer Institute (NCI) tested their cytotoxicity against a variety of cancer cell samples.
One derivative tested by NCI, designated as macrolactone 11, is currently under evaluation as a preclinical drug candidate, Nicolaou said. Related compounds macrolactone 33 and 44, which he said showed evidence of even higher potency against leukemia, lung cancer, colon cancer, melanoma, renal, prostate cancer "and several more we did not include in this paper," are also being considered for further testing by Texas Medical Center collaborators.
Results obtained in collaboration with the group of Mark Brönstrup, a professor at the Helmholtz Centre for Infection Research in Germany, led the researchers to suspect the molecule works by inhibiting the export of a translocation biosensor from a cancer cell's nucleus through a covalent addition to an export receptor.
The lab continues to develop drug candidates based on prostaglandin. "The macrolactones are very good – better than the natural product – and now we're following this lead to optimize the potency while minimizing toxicity. It's a balancing act," Nicolaou said.
Postdoctoral researchers Kiran Kumar Pulukuri and Stephan Rigol, graduate student Ruocheng Yu and lab alumni Charles Grove, Philipp Heretsch, Christopher Hale and Abdelatif ElMarrouni, all of Rice, are co-authors on the Chemistry – A European Journal paper.
Pulukuri, Rigol, Heretsch, Yu, Grove, Hale and ElMarrouni as well as Brönstrup and Verena Fetz of the Helmholtz Centre for Infection Research, Braunschweig, Germany, and Monette Aujay, Joseph Sandoval and Julia Gavrilyuk of Stemcentrx Inc., San Francisco, are authors of the JACS paper.
The National Institutes of Health, the Cancer Prevention and Research Institute of Texas and the Welch Foundation supported the research.


Whether your name or the name of a dear loved one, this 18K gold-plated Silver necklace is one-of-a-kind beautiful. Your choice of name measures can be up to eight letters long. Suspending from a box chain, this necklace is all about you.


text:
Ex-solon asks SC to declare DAP unconstitutional
Oct 7, 2013 4:14 PM PHT
Former Iloilo Representative Augusto Syjuco Jr also asks the High Court to recommend administrative charges vs Budget Secretary Abad and Senate President Drilon
MANILA, Philippines (Updated) – A former congressman on Monday, October 7, asked the Supreme Court to declare the government's so-called economic stimulus package – now known as the Disbursement Acceleration Program (DAP) – as unconstitutional and stop the budget department from implementing it further.
Former Iloilo Representative Augusto "Boboy" Syjuco Jr also urged the SC to recommend the filing of administrative and criminal charges against Budget Secretary Florencio "Butch" Abad and Senate President Franklin Drilon.
In his petition, Syjuco called Drilon, his rival in local politics, as the alleged "promotor" of using the "fictional" DAP to push for the impeachment of former chief justice Renato Corona in May 2012. Drilon was the chairman of the Senate finance committee at that time.
Meanwhile, the ex-solon said Abad should be held accountable since DAP was created not by virtue of an Executive Order from the President but merely by a memorandum from the Department of Budget and Management.
According to the petition, the Constitution asserts that all appropriations must pass through Congress, and an office can only augment or re-align items that are included in the general appropriations law. It also cites that the augmentation should be taken from the savings of the respective office.
The former lawmaker specified 3 main reasons why DAP was unconstitutional:
No law was passed and promulgated for the creation of the DAP.
Funds allocated for DAP were taken from budgets of slow moving projects which were not completed nor performed and therefore are not savings in itself.
DAP was and is being used to augment new budget allocations or list not approved by the legislature.
Drilon earlier admitted the DAP releases were sourced from unused funds from various line agencies, and were used to fund items outside the budget.
READ: Drilon admits receiving P100M after Corona trial
Sen Jinggoy Estrada earlier accused Malacañang of enticing senators to vote to oust the Chief Justice in exchange for P50 million each.
Abad denied the additional releases to senators were bribes. He said the releases, ranging from P23 million to P100 million for senators, were in fact part of DAP.
Syjuco earlier filed plunder charges against Drilon, his known rival in Iloilo politics.
Drilon's response
In a statement, Drilon said he would in due time answer the allegations made in the petition.
He, however, denounced his inclusion in the petition as "a clear effort by Syjuco and his camp to muddle the issue on the DAP funds" and to remove public attention from the "corruption" involving lawmakers' Priority Development Assistance Fund.
Syjuco, however, did not receive his mandated PDAF in his last term under the Aquino administration, as did other vocal Aquino critics in the House.
A Rappler report also identified Aquino allies also involved in the systematic misuse of lawmakers' pork barrel.
READ: Admin solons linked to pork barrel scam too
Drilon said his critic was misinformed when Syjuco called him the "promoter" of the allegedly illegal releases.
Without addressing questions on the releases' constitutionality, the Senate President said: "The DAP allocation is not cold cash and but was merely a list of infrastructure projects recommended by legislators and local government officials to be implemented by the Department of Public Works and Highways."
Drilon said "the P100 million I requested under the DAP in December 2012 was…utilized to fund infrastructure projects in Iloilo City, which was eyeing to host the Asia-Pacific Economic Cooperation ministerial meeting in 2015."
A Liberal Party ally at the House of Representatives supported moves to bring questions over the legality of DAP to the SC.
"I think that is best that we bring this issue to the Supreme Court and find out who's got the strongest legal position on this matter about the DAP," said Iloilo Rep Jerry Trenas. "But until then, I think that there is no legal stumbling block for the Department of Budget and Management if it decides to continue implementing DAP."
Syjuco's petition is the 2nd complaint against DAP lodged before the SC.
SC petition vs DAP

redpajama_set_name: RedPajamaCommonCrawl


Cuba. Angela Ms. Weinberg 4 th Grade. Where Cuba is located. The continent is North America. The bodies of water near Cuba are the Atlantic Ocean and Caribbean Sea. The countries next to Cuba are the United States, Bahamas and Jamaica. Animals of Cuba.
The continent is North America.
The bodies of water near Cuba are the Atlantic Ocean and Caribbean Sea.
The countries next to Cuba are the United States, Bahamas and Jamaica.
Sports and games they play are baseball and jai alai.
The leader of the country is Fidel Castro.
The name of the money is the peso and jaiala.
The language they speak in the country is Spanish.
The food they eat is congri and pollo.
The flag is red, white, and blue. It has a star and triangle.
The most interesting place in Cuba is Havana.
The land is beautiful in Cuba.
Mara, Willam ,Cuba. Minnesota: Bridgestone 1999.


Wisdom of the Crowd within Enterprises: Practices and Challenges.
Hosseini, M., Moore, J., Almaliki, M., Shahri, A., Phalp, K. T. and Ali, R., 2015. Wisdom of the Crowd within Enterprises: Practices and Challenges. Computer Networks., 90, pp. 121-132.
The Wisdom of the Crowd advocates that decisions collectively made by a diverse crowd could be better than those made by an elite group of experts. The Wisdom of the Crowd puts preconditions on this to work correctly. This concerns the di- versity of the crowd, their independence from each other, their decentralisation, and the methods of aggregating their distributed knowledge and forming collec- tive decisions. Although the concept is inspiring, its interpretation and conduct differ significantly amongst enterprises, especially with regard to the culture and style of management. In addition, we still lack reflections on how the Wisdom of the Crowd worked in the practice of modern enterprises. To address this lack of knowledge, this paper conducts an empirical study following a mixed method approach involving 35 senior managers coming from 33 different industries in the UK. In the first phase we interview eight managers and, in the second, we con- firm and enhance the results by a survey consisting of open-ended questions and involving 27 other managers. The results shed light on the current practice of the Wisdom of the Crowd in several UK enterprises, which can inform the analysis and design of future software tools meant to aid this emerging decision-making mechanism.


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Shareholders were updated on the planned expansion of Falcon Cement Company's (FCC) production capacity, (Bahrain's first cement plant) bringing it up to a capacity of 3500t/day. The company said that the expansion of FCC will help it to meet Bahrain's growing demand for cement, where there is an increasing number of infrastructure projects.
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SPRINGFIELD — MGM Resorts recently detailed how and why the MGM Springfield design has evolved over the last four months. In a public presentation at CityStage in downtown Springfield, MGM executives, led by President Bill Hornbuckle, walked hundreds of attendees through the enhanced design plan, highlighting changes that allow for both design and operational efficiencies. The late-afternoon forum was hosted by Mayor Domenic Sarno and his economic-development team, led by Chief Development Officer Kevin Kennedy. "We are very proud of MGM Springfield's improved design," Hornbuckle said. "Our commitment to the city of Springfield, the region, and the Commonwealth has never wavered. Today, I am hopeful that people will see it has only gotten stronger. We are as ready as we have ever been to help return downtown Springfield to its glory days." The MGM team presented a detailed comparison of commitments in the May 2013 host-community agreement and the new design plan, with an amenity layout resulting in a less than 1% adjustment in square footage to be experienced by customers. While some amenities, such as the child-care facility and retail, have grown in size, other operational and back-of-the-house spaces were reduced through design efficiencies. A redesign was made public earlier this fall when MGM Springfield announced it was moving the 250-room hotel along Main Street and market-rate apartments off-site. With the changes, MGM hopes to further engage Main Street while promoting ancillary development opportunities with off-site market-rate apartments. MGM is currently negotiating the purchase of 195 State St., the former Springfield School Department headquarters, to move forward with a housing redevelopment at that property. Brian Packer, MGM's vice president of construction and development, joined Hornbuckle on stage, giving a construction update. Packer said that the company already has spent more than $23 million on MGM Springfield construction and employed 675 construction workers. Many of those workers were involved in the renovation of the new Mission on Mill Street, providing an updated, secure facility that will house a rehabilitation program, giveaway center, and business offices. Additionally, Packer laid out a sequence of construction events that will lead up to the September 2018 opening. The company estimates it will now cost more than $950 million to open MGM Springfield. Original estimates were expected to exceed $860 million, including capitalized interest and land-related costs. "MGM Springfield is not only the largest development project Western Massachusetts has ever seen, it is starting to rival the investment of the most-talked-about about development projects in the Commonwealth," said Michael Mathis, MGM Springfield president. "We developed this presentation to provide transparency on our process. The people of Western Massachusetts want to be excited about the once-in-a-lifetime opportunity that is MGM Springfield. We know maintaining a level of positive energy is our responsibility. Major demolition, large contract awards, and exciting opportunities to get involved are all part of the next phase, which will start very soon." MGM is scheduled to present a comprehensive cost and design analysis to the Mass. Gaming Commission on Dec. 3. The mayor and City Council must still approve the updated site plans before MGM can go forward with its design-approval process.
BOSTON — The state's total unemployment rate remained at 4.6% in October, the Executive Office of Labor and Workforce Development announced Thursday. The preliminary job estimates from the Bureau of Labor Statistics indicate Massachusetts added 11,000 jobs in October. The largest over-the-month job gains occurred in the education and health services; professional, scientific, and business services; and other services sectors. Year-to-date, Massachusetts has added 62,800 jobs. The Bureau of Labor Statistics also revised preliminary job estimates for September that originally indicated Massachusetts lost 7,100 jobs. BLS revised estimates for September show the state lost 2,200 jobs. The October preliminary estimates show 3,396,900 Massachusetts residents were employed during the month, and 164,000 were unemployed, for a total labor force of 3,560,900. The labor force decreased by 8,700 from 3,569,600 in September, as 9,600 fewer residents were employed and 900 more residents were unemployed over the month. Over the year, the state's seasonally adjusted unemployment rate fell 0.9% from 5.5% in October 2014. There were 32,000 fewer unemployed persons over the year compared to October 2014. The October state unemployment rate remains lower than the national rate of 5.0% reported by the Bureau of Labor Statistics. "Massachusetts continues to add jobs, and the labor market is strong. We frequently hear from employers that they have jobs to fill, which is a good position for the state to be in," Labor and Workforce Development Secretary Ronald Walker II said. The state's labor-force-participation rate — the total number of residents 16 or older who worked or were unemployed and actively sought work in the last four weeks — decreased 0.2% point to 64.7% over the month. The labor-force-participation rate over the year has decreased 0.8% compared to October 2014. The largest private-sector percentage job gains over the year were in professional, scientific, and business services; construction; other services; leisure and hospitality; and education and health services.


text:
Home Live Blog Archive Show Notes for Wednesday, September 18, 2013
Live Blog Archive
Show Notes for Wednesday, September 18, 2013
• Rep. Jim Moran (D-VA) calls in at 10am ET / 7am PT with his thoughts on the situation in Syria
• Sexy Liberal Hal Sparks joins us in the Los Angeles Bureau at 11am ET / 8am PT for Humpdays With Hal
• The Navy was told by authorities in Rhode Island last month of an incident in which Aaron Alexis complained that he was hearing voices, according to a police report on the incident. It is unclear whether the Navy followed up.
• President Obama has ordered a comprehensive review of government contractor and employee protections. The move comes in the wake of the mass shooting at the Washington Navy Yard, which raised concerns about security procedures at U.S. military installations.
• A day after a mass shooting left 13 dead in DC, federal gun legislation is in the same place as it's been for months: stalled in Congress. Still stung by an April defeat in the Senate, discouraged proponents of gun control legislation say that the chances for change are still dim.
• President Barack Obama said the world would still be better off if Bashar Assad left power, but on Tuesday stressed that his top priority was removing chemical weapons from the Syrian president's arsenal.
SMHH VideoCast F 1-27-23 with Joyce White Vance & John Fugelsang
SMHH VideoCast with Cliff Schecter – 1-13-23
SM Happy Hour VideoCast 03-25-22 Phillip from Ukraine & AG from Mueller She Wrote


Handmade in Texas. Made in the USA.
comes with a onyx zipper and our classic black and white stripe wipeable interior. Large bag comes with a colorful tassel.
Care Instructions: Savannah is machine cold wash only, hang to dry, do not use iron.


text:
The 8-Bit Guy
Open House / VIC-20 Repair Day Info
2023 Scheduled Appearances
8Bit Guy: About
Petscii Robots
Petscii Robots Shareware Downloads
Where is Petscii Robots Arcade?
GeekBits Podcast
Petscii Robots – Which version is best?
Posted by The 8Bit Guy | Last updated Oct 21, 2022 | Blog, Petscii Robots | 26 |
Since the game now runs on some 20 different platforms, I'm often asked "which version is the best?" Well, the simple answer I usually give is, "the best version is the one that runs on your favorite platform!" So if you're an Apple guy, the Apple version is best, if you're a Commodore guy, then the Commodore version is best, and so on. And that generally holds true. In fact, the C128 version is my personal favorite.
But, what if you weren't familiar with any vintage platforms and you were just interested in trying out the game? Or maybe you have multiple vintage systems and you're not sure which one of those is the best experience for this particular game? That being the case, I have ranked them all here for you from best to worst, based on my own experience and opinions. Only mostly-finished or finished ports are listed.
Here's a comparison video showing all 18 versions.
That being said, I think the game is enjoyable on all platforms, and sometimes you have to take some context in mind. For example, the PET is rated towards the bottom. But that doesn't mean it isn't a great game for the PET. In fact, I think it's one of the best. It's just hard for a PET to compete with an Amiga, for example.
MS-DOS (VGA+AdLib)
Sony PlayStation Portable
Commodore 64 REU
Commander X16
Commodore Plus/4
MS-DOS (CGA+PC Speaker)
Atari 800
Commodore VIC-20
Sinclair ZX-Spectrum
Some of those were tough to decide. Some people may even disagree. For example, the Plus/4 vs. the C64 version. The C64 has better music, and some of the graphics look better. But the Plus/4 has a better intro screen and better map. So, it's kind of a tie. Same with the C128 and C64-REU version. They're virtually identical. The C128 wins because it has faster disk access and dual-monitor support. The VIC-20 and PET version just about tie as well. The VIC-20 has color, which is huge. But the PET has a larger player area, more maps, more easter eggs, and of course a live-map.
So anyway, there you have it. Even though the game was originally designed on the PET, there are 9 other platforms which now play the game better than the original.
In time I'll be adding these to the rankings when they are completed. It's not fair to compare complete games against incomplete ones.
Nintendo SNES
Tandy Color Computer 3
Oric-1
PreviousPetscii Robots for Apple II now available!
The 8Bit Guy
Planet X2 for the Commodore 64 is Finished!
New maps for Planet X2, free download
Planet X3 is Here! And with new video modes!
My dream computer – Part 2
Last updated Oct 31, 2021
gadgetboi on May 16, 2022 at 9:56 am
I love the Sega genesis version
Johny on May 16, 2022 at 1:54 pm
Can we expect Amstrad version?
Christopher Rutherford on May 17, 2022 at 1:53 am
Spectrum version would be relatively easy to port to another z80 system like an Amstrad or MSX
Craig beazley on May 16, 2022 at 3:29 pm
Hi 8BitGuy
I am very interested in the Genesis version of the game. Problem… I'm based in the UK. So I'm toying with the different options.
1) Is the game playable on the Sega Mega Drive Mini using Hackchi?
2) Is the game playable on a PAL Sega Mega Drive and seeing as a UK Mega Drive runs slower will it ruin my experience?
3) Can you ship to the UK and how much does it cost?
Look forward to hearing from you. Keep up the fantastic work. It looks a great game and I hope I can play it either on the standard Mega Drive or the Mini (which runs the same across all regions).
The 8Bit Guy on May 16, 2022 at 3:32 pm
I'm not familiar with Hackchi. It should work on a PAL Megadrive according to the developer, but I haven't personally tested that as I don't have a PAL machine. Yes, I ship to the UK. Shipping will be $15.
Stuart on August 17, 2022 at 12:24 am
I think petscii robots version 2 is the best. The one with more robots, more weapons, new maps etc, you know, the one you have yet to make 🙂
Timonthy on January 10, 2023 at 6:09 am
Hello, Murray.
Just wondering if there is a possibility for a few more ports, like the PC-98, X68000, MSX, Famicom Disk System, Osborne, PS2 3DO, SNK Neo-Geo, Turbografix-16, Mega CD32 (or just Sega 32X), Master System, Game Boy (or GBA), BBC Micro, Amstrad, ZX81, Atari ST, Jaguar or Lynx and/or the
68k Macintosh computers (later ones, or perhaps early PowerPC ones)?
The 8Bit Guy on January 10, 2023 at 10:38 am
If somebody wants to make them, sure.. but I'm not going to be involved. Also some of the computers you mentioned have been looked at and determined that it is simply not possible to port, such as the BBC Micro and ZX81. There just isn't enough RAM.
Sean McGrail on May 16, 2022 at 3:57 pm
Thanks for posting this video, I've wanted to check out this game, and was excited to see that this was available for PSP! That means this can also be played on a PS Vita or PS Vita TV if properly modded. I was able to boot up the game just fine after downloading it from your site and moving it over to my vita. I also own a PSP but haven't pulled that out in a long time since the Vita can do double duty.
Paul on May 16, 2022 at 5:05 pm
Put me down for the snes vision please and a vinyl record…uk pal vitriol
Gerry Temple on May 16, 2022 at 7:29 pm
LOVE this project – it's become huge! Idea: as I'm using several old machines I'd be highly interested in buying more than one version. So I thought it would be fantastic to buy several different versions for a special price – or if that's a problem for your store – to get ALL versions for a special price. Cheers from Germany and keep up your brilliant work!
I'm sure if you send me a private email we can work something out.
Athanasius on May 17, 2022 at 5:41 am
The PET-version is the most impressive on a technical/programming standpoint. I enjoy playing it very much as there is much beauty and elegance in it's most basic form. Without any doubt it's the best version that ever graced the PET. My favourite version is either the Amiga- or the C128- version. I really love the very helpful map and the colourful depiction of the action.
I'll definitively buy the Sega Genesis-version next. And the DOS-version too.
Hyperslime64 on May 17, 2022 at 8:59 am
Im really excited for the Genesis version as it's the only one I can technically play on real hardware. (I do own a VIC-20 and Datasette, but no disk drive or RAM expander.)
doug johnson on June 9, 2022 at 8:16 pm
I think I am using version 1.2 these.
C128 Pro: Map screen and all 14 levels. Con: Some of the ground/grass graphics are to busy. (Not a fault of the game but VICE is unable to restore correctly from snapshot.)
Amiga Pro: Excellent graphics sound and map screen, all 14 maps. Con: Music track seems not changeable. Prevents Amiga-Forever from saving a snapshot.
C64 REU: Pro: Like the larger map view and contains all levels. Con: Some of the ground/grass graphics are to busy.
C64: Pro: Like the graphics and play speed. VICE can reload from a snapshot. Con: Short one level. Map view a little small but better than having nothing.
Would like to see C64 v1.3 that has all 14 levels, larger map screen like the REU version and supports the REU but keeps using text mode. Use *.d81 file only.
Thank you for creating this game and for all the others who have worked on ports. Looking forward to the MS-DOS version.
The 8Bit Guy on June 9, 2022 at 9:06 pm
One thing we originally wanted to do on the C128 and C64REU versions was to have user-selectable tiles like on the Apple II version. We wanted to have a hi-res mode and multi-color mode. But we never got around to creating the hi-res graphics. They would have had a similar look to the text mode due to color limitations, but with maybe a bit more detail in some areas.
TJ HOOKER on June 30, 2022 at 6:46 pm
I have the Apple II (with Mockingboard) and VIC-20 (with SNES controller) versions and I enjoy them both very much. Planning on getting the DOS version as I have a Tandy TX with a VGA card but wondering if Tandy sound will be supported?
The 8Bit Guy on June 30, 2022 at 8:16 pm
I haven't decided on Tandy sound yet. But Tandy Graphics is almost a no-brainer since it doesn't require much work to support it.
Marc-Andre Larouche on July 8, 2022 at 10:18 am
Genesis > Amiga in my opinion, swapping items is better with the menu and you can move objects more easily, but I don't like the control to use bomb, because I keep pushing the button to use the item (as I'm use to press a button to confirm my choice) so instead of placing the item, it laid a second bomb and I blow myself up! Happens every time, I can't wrap my head around this for some reason.
Otherwise I like the Genesis music, mechanics and 2 players mode better.
Alex Stone on September 7, 2022 at 11:53 pm
Hello 8-Bit Guy. Great Content as always. Have you ever thought of porting it to Android Phones or for a challenge port it to a TI-84 calculator.
I really liked your videos where you go through the development of the game and how you optimize it. It would be cool to see another devlog discussing the difficulties each port had.
John on October 12, 2022 at 2:04 pm
Which is the best (C64 or REU) version of PETCSII for the retrogames TheC64 orMini or maxi? I would like to play the game from an SDCARD. I already have both Planet X2 and X3.
The 8Bit Guy on October 12, 2022 at 2:20 pm
Those devices do have REU support. But you probably have to make a configuration file for the game to run that way. I don't have that handy. So, the REU version would look best. But the standard version would be easiest to get running.
andrea on October 15, 2022 at 4:15 pm
Hello 8-Bit Guy!
I've been running Petscii Robots both on my C64 and my C64C, and although it looked milder on the C64C, I noticed some serious color fringing issues. I've asked around online and I've been told that since the game was created for NTSC computers, running it on a PAL machine might make it misbehave like this. That's something I didn't consider this at all when I purchased it, and I am, indeed, running it on PAL machines. Can you confirm this hypothesis and you have any idea whether this problem is fixable at all?
The game uses a lot of single-pixel or alternating pixel graphics…. on a lot of composite monitors it can create weird artifacts. If you use a Commodore monitor with LCA mode, it should look fine.
Wesley on December 11, 2022 at 6:31 pm
Am I crazy, where can we get the dos version? You have it listed but nowhere to buy. Is it still in development? Otherwise will need to settle for psp I think.
The 8Bit Guy on December 11, 2022 at 7:02 pm
DOS version isn't finished yet.
8-Bit Keys
Commodore History
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Design solar panel with bateries for pc fan at radiation shield part 2.
I make a electronic circuit with 2N2222 tranzistor, and CA3140E microcircuit, i drive to relay with better accurace,with trimmer i tuning at how voltage i want to drive the relay.
Edited 3 times, last by weather19671967 ( Oct 17th 2009 ).


text:
Q: How to Pass Variables into Script Transformation Editor? I would like to pass Variables from my package into Script Transformation Editor. How do I add this into my Row.Reference1 below?
Here's the script that I use:
Imports System
Imports System.Data
Imports System.Math
Imports Microsoft.SqlServer.Dts.Pipeline.Wrapper
Imports Microsoft.SqlServer.Dts.Runtime.Wrapper

Public Class ScriptMain
    Inherits UserComponent

Public Overrides Sub Input0_ProcessInputRow(ByVal Row As Input0Buffer)

        Row.Column1 = Tokenise(Row.Column0, "|", 1)
        Row.Column2 = Tokenise(Row.Column0, "|", 2)
        Row.Column3 = Tokenise(Row.Column0, "|", 3)
        Row.Column4 = Tokenise(Row.Column0, "|", 4)
        Row.Column5 = Tokenise(Row.Column0, "|", 5)
        Row.Column6 = Tokenise(Row.Column0, "|", 6)
        Row.Column7 = Tokenise(Row.Column0, "|", 7)
        Row.Column8 = Tokenise(Row.Column0, "|", 8)
        Row.Column9 = Tokenise(Row.Column0, "|", 9)
        Row.Column10 = Tokenise(Row.Column0, "|", 10)
        Row.Column11 = Tokenise(Row.Column0, "|", 11)
        Row.Column12 = Tokenise(Row.Column0, "|", 12)
        Row.Column13 = Tokenise(Row.Column0, "|", 13)
        Row.Column14 = Tokenise(Row.Column0, "|", 14)
        Row.Column15 = Tokenise(Row.Column0, "|", 15)
        Row.Column16 = Tokenise(Row.Column0, "|", 16)
        'Row.Reference1 = ???

    End Sub

Private Function Tokenise(ByVal input As String, ByVal delimiter As String, ByVal token As Integer) As String

        Dim tokenArray As String()
        tokenArray = input.Split(delimiter.ToCharArray) 'Split the string by the delimiter
        If tokenArray.Length < token Then 'Protect against a request for a token that doesn't exist
            Return ""
        Else
            Return tokenArray(token - 1)
        End If
    End Function
End Class

A: On the "Script" page of the Script Transformation Editor, the last section is "Custom Properties". There are two properties: ReadOnlyVariables and ReadWriteVariables. Set those that are appropriate to a comma-separated list of the variables you want the script to reference.
When you click the "Edit Script" button,  you'll find that the Variables class created in the ComponentWrapper.vb now has properties with the names of the variables. The read-only variables will exist as readonly properties; the ReadWrite variables will exist as properties with both a getter and a setter.
You then reference them as, for instance, Variables.TaskID.

redpajama_set_name: RedPajamaStackExchange


Welcome to my Wednesday. I want to thank you for stopping by and checking out another day in my life. I hope you are having a great day in yours as well.
I ended up going to bed very early yesterday. Actually I laid down for a nap around 4pm yesterday and slept until this morning at 10am. I guess going to the meeting at NFAN yesterday took more out of me than I realized. I know I had a killer headache again by the time I returned home. My headache continued worsen until I had to lie down and next thing I knew it was morning.
So unfortunately I missed all the Olympic coverage last evening. On her fourth and final chance, Shawn Johnson won her gold medal with a nearly flawless routine on balance beam. At the end she unleashed a smile as big as Beijing itself, a glorious conclusion to a competition that never got her down and only taught her more about herself as she came to appreciate the journey as much as the destination. The 4-foot-9 powerhouse from Iowa had won over the fans here with her strong performance and profound grace. Shawn Johnson finally got her Olympic gold medal in the last event of the women's competition Tuesday night, the balance beam. Johnson nailed her routine that is chock-full of difficult tricks, earning a 16.225. Her grin was a thousand times wider than the 4-inch-wide beam she had just conquered. The world champion, who already had a silver behind fellow American Nastia Liukin in the all-around, and a silver on floor and in the team event, edged Liukin, who finished with a gold, three silvers and a bronze. Cheng Fei of China took the bronze, giving China six women's medals, two behind the United States. I wish I could have caught her finally winning a gold. She is one of my personal favorites from this Olympics.
Luckily, I have what I consider to be good news about Tropical Storm Fay. Tropical Storm Fay moved inland Tuesday after making landfall in southwest Florida, never growing into the hurricane that forecasters had cautioned it could become. There was street flooding in spots and minor storm surge damage was reported in Everglades City to the south. This morning the center of the Fay was about 30 miles east of Fort Myers and was moving north-northeast near 9 mph with maximum sustained winds of 60 mph expected to gradually weaken through the day. It could strengthen slightly once it crosses Florida to the Atlantic and gets over water again. Flooding remained a concern as Fay heads up the Florida peninsula, with rainfall amounts forecast between 5 and 10 inches. The storm could also push tides 1 to 3 feet above normal and spawn tornadoes. Florida Power & Light reported about 58,000 homes and businesses without power in South Florida early Tuesday, the largest number in Collier County, where 28,000 were in the dark. After crossing the Florida Keys without causing major damage Monday, Fay lumbered ashore about 5 am Tuesday at Cape Romano, just south of Naples, with sustained winds of about 60 mph. Cape Romano is the same spot where Hurricane Wilma, a Category 3 storm, made landfall in October 2005. So we have been very lucky so far here in the states. As it moved though the Caribbean, Fay was blamed for at least 14 deaths in Haiti and the Dominican Republic, including two babies who were found in a river after a bus crash. Keep those fingers crossed and hopefully we will have no major injuries or fatalities from the storm. Thanks for all of you who sent emails wishing us well during the storm. They are still forecasting the storm to be in Jacksonville in the next couple of days according to the current models. But hopefully the winds will be way down and our only danger will be the possibility of flooding and/or tornadoes.
I was suppose to have an appointment with my infectious disease doctor (HIV doctor) today. But his office had called yesterday to reschedule me to next week. I really wish I could have gone today and had him check my lungs again. I just finished my last course of antibiotics but I still have a bad wheezing when I breathe. I almost sound as bad as Gary when he is snoring. Well, maybe not that bad. LOL. Todd Reese, an old friend of mine, is now the new office manager at AHF which should greatly improve the operation of the office. Todd brings a ton of experience and a true empathy for the patients to the job which was missing in previous managers.
I heard from my friend, Butch McKay, who is over OASIS in Ft. Walton Beach, Florida. I met Butch and the rest of his staff at their HIV convention this past March and have enjoyed getting to know him over the past several months. I knew from the opening speech Butch gave that we had a lot in common and would probably make great friends. I ended up taking 8 members of my support group to the convention and everyone had a great time. He and his partner recently celebrated their 31st anniversary which is a huge accomplishment regardless of your sexual orientation. So Happy Anniversary guys! I hope you have another very happy 31 anniversaries in your future. Butch works tirelessly helping people with HIV and AIDS for many years. Butch, like I, has lost many close friends to AIDS over the years. If you would like more information about OASIS and the work Butch does please click on the OASIS icon on our links/resource page.
I would also like to thank all of you for your get well cards and messages. You know how to make a guy feel special and loved. I am eternally grateful for your thoughts and prayers. Do not worry because I do not plan on going anywhere. Too damned mean to leave until I am good and ready and guess what. I am not ready. My current health problems are just a bump in the road. You can not keep a good man down.
So that is about it for my day. How was yours? Remember to live life and enjoy it. Too many people go through life on automatic pilot. Don't be one of them.


text:
HomeNewsMark Thompson to Become Visiting Professor
Mark Thompson to Become Visiting Professor
Mark Thompson, outgoing director general of the BBC, is to take up position as a Humanitas Visiting Professor at the University later this year.
On Friday 14th September the University announced that Thompson (Merton, 1976) will take up its first Professorship in Rhetoric and the Art of Public Persuasion, a position created in honour of Philip Gould. Thompson will assume his new role in early November 2012, before he takes up his future position as Chief Executive of the New York Times.
Thompson will deliver a series of lectures in the week beginning 5th November as part of the role. Taking place at St Peter's College, the lectures will analyse the language of political debate in the UK and the USA.
They will, among other issues, consider healthcare and language, science and argument, and the war on morality. The series, entitled The Cloud of Unknowing, will culminate in a symposium -- featuring Andrew Marr, David Willetts, Polly Toynbee and Gus O'Donnell -- which will discuss how language shapes public debate.
Thompson, who read English at Merton College, has remarked to the University that "as an Oxford humanities graduate, it means a great deal to... be asked to become the university's first visiting professor of rhetoric and public persuasion." He went on to explain that the "lectures spring from an abiding interest in language and argument".
Alumni can register for a place at one of the lectures on the Humanitas website.
Humanitas Visiting Professor


1. Set yourself up for success in the new year. With 60+ easy & delicious low-calorie recipes, inspiring success stories, a healthy grocery cart makeover, and so much more, this special keepsake issue will kickstart your SKINNY NEW YEAR! You'll be on your way to a healthier, happier YOU.
2. It's a FANTASTIC gift for your food-loving friends. This is no ordinary magazine. Hungry Girl magazine is a thick, high-quality publication that's exploding with brand-new content! Plus, you can have it sent directly to a friend's or family member's doorstep. You'll even get a cute downloadable gift card to let them know their gift is on the way!
3. It's the ONLY way to guarantee you get a copy. While the magazine WILL be available in stores starting in late December -- Walmart, Target, major supermarkets, and more -- not every store location will carry it. Plus, shipping is free, so it won't cost you a penny more.
Orders will ship in 2 - 4 weeks. Ordering from Canada? Click here.
Here's MORE of What's Inside!
⭑ Your Ultimate Dining-Out Guide - How to make the smartest food choices WHEREVER you go.
Remember, ordering now is the ONLY way to ensure you get yourself a copy of this must-have magazine. Mail-order quantities are limited, so act now! Shipping is FREE, and you'll get an adorable downloadable gift card when you order for a friend. I just know you'll love it as much as I do!
Happy Bathtub Party Day, December 5th! Add bubbles to your bath by sipping on a Sparkling Spiced Apple Sangria.
Click "Send to a Friend" to share the news!


text:
package com.elphin.framework.util.strategy;

import android.util.Log;

import java.util.LinkedList;
import java.util.List;

/**
 * Created with IntelliJ IDEA.
 * User: elphin
 * Date: 13-7-3
 * Time: 下午2:54
 */
public class StrategyHandlerList<T> {

    private static final String TAG = StrategyHandlerList.class.getSimpleName();

    private List<StrategyHandler<T>> mStrategyHandlers = new LinkedList<StrategyHandler<T>>();

    public StrategyHandlerList() {
    }

    public StrategyHandlerList addHandler(StrategyHandler<T> handler) {
        if (handler != null) {
            mStrategyHandlers.add(handler);
        }
        return this;
    }

    public boolean handle(T inParam) {
        final List<StrategyHandler<T>> list = mStrategyHandlers;
        boolean handled = false;
        for (StrategyHandler<T> handler : list) {
            Log.d(TAG, "handler : " + handler.getClass().getSimpleName());
            if (handler.handle(inParam)) {
                Log.d(TAG, "break handler : " + handler.getClass().getSimpleName());
                handled = true;
                break;
            }
        }
        return handled;
    }
}

redpajama_set_name: RedPajamaGithub


text:
Hitachi to provide world's fastest lift
Hitachi says it will provide the world's fastest elevator for use in a 111-storey building in China's Guangzhou city.
Glitch mars opening of world's tallest tower
Strong winds forced the operators of the Tokyo Skytree, the world's tallest tower, to shut down its lifts on its opening day Tuesday, leaving some visitors stranded on a 450-metre-high observation deck.
Woolworths says it expects to lift profits in FY12
Supermarket giant Woolworths says it still expects to lift net profit in the current year but admits the retail sector faces significant challenges.
How to avoid a margin call
Some margin lending may be more marginal than you think. And that's where many of the clients of Opes Prime and Lift have come unstuck.
By Gillian Bullock
Give your website a facelift
An up-to-date website will generate customers. Review our seven easy steps for making sure your small business website isn't doing more harm than good.
Read more Small business news


What types of investments are used by the Financial REITs to earn money for their shareholders?
Financial REITs invest in several types of financial assets, such as mortgage backed securities (MBS), as well as originating mortgages, and some companies engage in raising money for private and public companies and lending through structured financings.
How do you differentiate between the stocks in the Financial REIT group?
I always take a fundamental approach to my analysis, and also contrast the companies by valuation and the composition of their portfolios. Dividend coverage, as well, is very important to the choice of stocks in this group. Not all Financial REITs should be treated equally by investors. In the MBS area, for example, I think the sub-prime market is going to outperform the prime market, as it is not as interest rate sensitive as the prime market. For the structured finance group, interest rate increases are not much of a risk, but credit risk is important, if a borrower were to default on a loan.
Taxable earnings is what drives the dividend for a Financial REIT stock. For GAAP earnings, companies delay the recognition of income, whereas with taxable income, gains are recognized up front. Trends in taxable earnings are the signal for changes in the dividend. (REITs are required to pay out 90% of their taxable earnings as dividends to their shareholders).


text:
Pat Sheldon
(Radio) waves of greatness
By KARL PEARSON
Ask Pat Sheldon about his basketball skills and he will tell you that they were very ordinary.
But thousands of area players and coaches, not to mention fans, would quickly reply that few people have had a greater impact on the game in the area. Their esteem for Sheldon has nothing to do with his skills on the court, but the way in which he and his WFUN broadcasting buddies, Jim Cordell and Gene Gephart in the early years and Jon Hall, Ed Batanian and Gephart in recent years, have presented basketball for 38 years.
It is almost with a sense of bewilderment that Sheldon talks about his selection to the Ashtabula County Basketball Foundation Hall of Fame. He will be the media representative of the class of 12 inductees for 2007 at Sunday's annual banquet and awards ceremony at 6 p.m. at the Conneaut Human Resources Center.
"I was thrilled when I was informed," Sheldon said during a conversation at his office off Prospect Avenue. "I'm certainly honored.
"If there's a reason for it, I guess I would have to say it's my longevity. There are so many other people who are more worthy of the Hall of Fame than I am. I'm just a support person."
He is proud to be back in the company of broadcast partners Cordell and Gephart, who are previous inductees into the ACBF Hall of Fame.
"If it weren't for Jim, Gene and now Jon Hall, there would be no broadcast," Sheldon said. "I've tried to do a little play-by-play before with matters like Little League or the Conneaut girls softball team when they won the state championship (in 2000), but that only made me realize how much talent it takes to perform that role, and I admit I don't have that talent.
"It's unbelievable to me to be in the same company with Jim, Gene and Ed. When I consider that I'm also joining people I've admired for 75 years like Bob Ball and Bob Walters, it truly is amazing."
If not for Sheldon's intervention, though, the WFUN radio team might never have been formed.
"I was listening to a game on WICA (now WFUN) on my way back home from Geneva in 1969," Sheldon. "The disc jockey was so bad that I called (station manager) Dick Rowley to complain. He asked me if I thought I could put together a team that could do any better, and I said I could. That's when I recruited Jim and eventually Gene, who was retiring from coaching (at Ashtabula). The rest is history."
Long before he got involved in broadcasting, basketball was important to young Carey S. Sheldon Jr. Born Aug. 6, 1925 as the youngest of five children of Carey Seth Sheldon Sr. and Ruth (Dunbar) Sheldon, his mother was the first one to tag him with the name most people who know him call him.
"My dad said he would never name a child Junior," he said. "But when I was born, my mother said my dad was too busy to give me a nickname, so she just started calling me Pat. Carey is just my business name. Most people call me Pat."
He and his sister, Carol Keyes of Florida, who was born in 1923, are the lone remaining survivors of their siblings. Older children David, born in 1916, John (1919) and Dorothy (1921) all died relatively early in life.
"I've outlived all the Sheldon men by at least 25 years," he said. "My sister still lives in Florida. We're very close.
"My dad had kidney disease and diabetes and lost his sight. He died the week of Pearl Harbor. David died of diabetes when he was only 28. John died in 1964 of kidney disease. Dorothy died when she was 64."
Because of his father's work, including service as city manager from 1928-37, the Sheldons were of somewhat better means than most families in Ashtabula, even though young Pat's formative years were during the Great Depression.
"We lived on a seven-acre farm out on West Prospect behind what's now Kardohely's Restaurant and back in where Busy Beaver is now," he said. "We had a barn on the back of the property and we set up a basketball court on the second floor.
"It was about 75 feet long and had a slanted roof. My brothers and sisters and I all played up there all the time. I was probably 8 or 9 when I started playing."
It attracted a lot of the poorer kids in Ashtabula, too.
"We had a lot of kids like (Ashtabula County Football Hall of Famer) Ralph Mauro and Tony Collette play up there," Sheldon said. "I was able to play at the Y and in the church leagues in town. I even had kids going to church with me, not because they wanted to go to church, but because they wanted to play in the church league.
"But there was no church league for the Italian kids, so they came over to our barn to play a lot. My two older brothers took care of things there. My sisters even played there as well."
That was different than a lot of girls of that era.


text:
\section{APPENDIX}

\noindent {\bf Data, Masks, and Rings:}
As in \cite{Cholis:2021rpp}, we use {\it Fermi} Pass 8 data, version P8R3, between 4 Aug 2008 and 14 April 2021 (weeks 9 to 670 of \textit{Fermi}-LAT observations)\footnote{\url{https://fermi.gsfc.nasa.gov/ssc/data/access/}}. We use \textit{Fermi} {\tt ScienceTools P8v27h5b5c8} for selection cuts, exposure-cube files, and exposure maps\footnote{\url{https://fermi.gsfc.nasa.gov/ssc/data/analysis/}}. We use these exposure maps to convert the flux maps to maps of expected counts. We restrict to FRONT-converted {\tt CLEAN} data satisfying {\tt zmax = $100^\circ$}, {\tt DATA$\_$QUAL==1}, {\tt LAT$\_$CONFIG==1}, and {\tt ABS(ROCK$\_$ANGLE) < 52}. All of the data and templates we use are in Cartesian projection and cover galactocentric coordinates in the latitude range $-20^\circ < b < +20^\circ$ and the longitude range $-20^\circ < \ell < +20^\circ$. We bin the sky in pixels of size $0.1^{\circ} \times 0.1^{\circ}$, leading to 160,000 total pixels, although many of these are masked, including the pixels along the Galactic disk below $2^\circ$ in latitude. We account for the unequal solid angle subtended by the pixels by applying a correction factor in latitude.

\setlength{\tabcolsep}{6pt}
\begin{table}[t]
       \caption{The energy bins and the radii of the ``small'' and ``large'' masks, $\theta_{s}$ and $\theta_{l}$, used to mask point sources with test statistic less (greater) than 49, respectively. The last column shows the fraction of pixels masked relative to the total number of pixels in the inner $40^\circ \times 40^\circ$ Galactic center region, including both the 4FGL-DR2 catalog and the Galactic disk.}
    \begin{tabular}{r|rr|c}
            $E_{\textrm{min}}-E_{\textrm{max}} {\rm\,[GeV]}$ &  $\theta_{s} [^{\circ}]$ &  $\theta_{l} [^{\circ}]$ & Masked fraction\\
            \hline
             $0.275-0.357$ & 1.125 & 3.75 & 71.8\%\\
             $0.357-0.464$ &  0.975 & 3.25 & 62.9\%\\
             $0.464-0.603$ & 0.788 & 2.63 & 52.2\%\\
             $0.603-0.784$ & 0.600 & 2.00 & 38.5\%\\
             $0.784-1.02$ &  0.450 & 1.50 & 29.2\%\\
             $1.02-1.32$ & 0.375 & 1.25 & 23.4\%\\
             $1.32-1.72$ & 0.300 & 1.00 & 19.0\%\\
             $1.72-2.24$ & 0.225 & 0.750 & 16.3\%\\
             $2.24-2.91$ & 0.188 & 0.625 & 13.0\%\\
             $2.91-3.78$ & 0.162 & 0.540 & 12.9\%\\
             $3.78-4.91$ & 0.125 & 0.417 & 11.6\%\\
             $4.91-10.8$ & 0.100 & 0.333 & 11.5\%\\
             $10.8-23.7$ & 0.060 & 0.200 & 10.3\%\\
             $23.7-51.9$ & 0.053 & 0.175 & 10.3\%\\
        \end{tabular}
    \label{tab:PSF_vsE}
\end{table}

The energy binning for the data and the flux maps is as follows. We take photons with $0.275 {\rm \, GeV} \leq E_\gamma \leq 51.9  {\rm \, GeV}$ and subdivide them into 14 energy bins. The first 11 energy bins cover a constant log-width in energy. To ensure that each bin has a similar statistical impact in our fits, the final three energy bins cover a wider log-width in energy, which compensates for the diminishing gamma-ray flux at higher energy. The exact endpoint of each bin is given in the first column of Tab.~\ref{tab:PSF_vsE}. In the final three columns of this table, we also provide details of the point source mask utilized in \cite{Cholis:2021rpp} and in this work. We classify point sources from the 4FGL-DR2 catalog according to their test statistic (TS). We mask point sources with $\text{TS}\leq 49$ ($\text{TS} >49$) with circular masks with radius $\theta_s$ ($\theta_l$), which depend on energy -- any pixel that is within an angular distance of $\theta_s$ ($\theta_l$) contributes nothing to our log-likelihood in that energy bin. The values of these angular parameters are listed in the second (third) column of the table. To give a sense of the impact of this mask, we report the fraction of ROI pixels that are masked (including point sources as well as the Galactic disk) in the final column. At the lowest energies, a majority of pixels are masked, but at a GeV less than a quarter of pixels are dropped, asymptoting to 10\% of pixels at the highest energies.

\begin{figure*}
    \centering
    \includegraphics[width=0.45\textwidth]{rings_unmask_noROI_maxcount_20.png}~~
    \includegraphics[width=0.45\textwidth]{rings_mask_ROI.png}
    \caption{Photons passing our cuts with energy $1.02 {\rm \,GeV} < E_\gamma <  1.32 {\rm \, GeV}$, without (left) and with (right) the mask that we use for our data. For illustration purposes, we show the boundaries of the {\sf ICS\_1}, {\sf ICS\_2}, and {\sf ICS\_3} rings that vary independently in our fits. In the right panel, we show the region of interest in which we perform our fits.}
    \label{fig:data_mask_ring}
\end{figure*}

We show one energy bin of data in Fig.~\ref{fig:data_mask_ring}, expanded to $\pm 30^\circ \times \pm 30^\circ$ for purposes of illustration. This depicts our data in the range $1.02 {\rm \,GeV} < E_\gamma <  1.32 {\rm \, GeV}$. The left (right) panel is the data without (with) the mask described above. We also show the location of the three innermost rings of ICS emission where they intersect the Galactic disk. The outer edge of {\sf ICS\_1} is at 1.5 kpc from the Galactic center, the outer edge of {\sf ICS\_2} is at 2.5 kpc from the Galactic center, and the outer edge of {\sf ICS\_3} is at 3.5 kpc from the Galactic center. Note that, although {\sf ICS\_2} is an annular cylinder with no emission between 1.5 and 2.5 kpc, this ring contributes to emission inside of $-10^\circ \leq \ell \leq 10^\circ$ because of projection effects along the line of sight. The boundary of {\sf ICS\_3} shown at 3.5 kpc is also the outer boundary of the {\sf HI\_1} and {\sf H2\_1} rings that we use. In the right panel, we also show the ROI in which we perform our fits.

~\\ \noindent {\bf Best-Fit Ring-Based Astrophysical Fluxes:}
\begin{figure*}[t]
\begin{center}
\includegraphics[width=0.45\textwidth]{HI_rings.pdf}~~
\includegraphics[width=0.45\textwidth]{H2_rings.pdf}\\
\includegraphics[width=0.45\textwidth]{res_rings.pdf}~~
\includegraphics[width=0.45\textwidth]{ics_rings.pdf}
\caption{Best-fit spectra and 95\% credible intervals of the flux of the ring-based templates that were fit alongside the boxy bulge excess template. For the negative residual component, we show its absolute value in the lower left panel.}
\label{fig:spectra_r}
\end{center}
\end{figure*}
In Fig.~\ref{fig:spectra_r}, we show the spectra of the best-fit ring-based templates that were fit alongside the boxy bulge, which was the excess with the relative best fit conditioned on using ring-based templates. In the four panels, clockwise from top left, we show the {\sf HI} fluxes, the {\sf H2}  fluxes, the {\sf ICS} fluxes, and the ``residual'' fluxes. As is apparent, the dominant contributions of the {\sf HI},  {\sf H2},  and ``residual'' fluxes have smooth, power-law like behavior. The subdominant {\sf HI} and {\sf H2}  fluxes, which account for of order tens of percent of the emission of these components, show sharp, non-monotonic behavior between energy bins, which is very difficult to explain with any physical model. The sum of the absolute value of the ``residual'' components comprise tens of percents of the emission at low energies.

Most strikingly, the {\sf ICS} fluxes are extremely non-smooth in all energy bins: five of the six different rings come to dominate in at least one bin over the fourteen energy bins we fit. Four of the six rings have extremely jagged, non-smooth behavior. The two innermost rings, labelled {\sf ICS\_1} and {\sf ICS\_2} by the convention of \cite{Pohl:2022hydrogen}, which we follow, are somewhat smoother than the other {\sf ICS} rings.

~\\ \noindent {\bf Results with Macias et al.~maps:}
In Tab.~\ref{tab:resultsM} we report the results of performing the fits as described in the main text, but using the sixteen ring-based maps from \cite{Macias:2016nev, Macias:2019omb, Abazajian:2020tww} instead. Compared to the results in the main text using the ring-based maps of \cite{Pohl:2022hydrogen}, the quality of the fits is substantially worse for every model of the excess. In addition, we observe that the ``residual'' components dominate the emission unless strict priors are imposed.

\begin{table}[t]
\caption{Comparison of the templates of \cite{Macias:2016nev, Macias:2019omb, Abazajian:2020tww} to the templates from \cite{Pohl:2022hydrogen}, as in Tab.~\ref{tab:results}.}
\begin{center}
\begin{tabular}{c|l|l}
Excess Model & $-2 \, \Delta \! \ln \cL$ & $\Delta \!\ln \mathcal B$ \\ \hline
No Excess & $+9828$ & $-4790$ \\
X-Shaped Bulge & $+9851$ & $-4901$ \\
Dark Matter & $+9512$ & $-4643$ \\
Boxy + X-Shaped Bulges & $+7808$ & $-3778$ \\
Boxy Bulge & $+7805$ & $-3897$ \\
Boxy Bulge ``plus'' & $+8026$ & $-3907$
\end{tabular}
\end{center}
\label{tab:resultsM}
\end{table}%

\end{appendix}

redpajama_set_name: RedPajamaArXiv