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"I've never known a man to know so much about so little." - J. Todd Smith
Movies and TV in 2020
The Road to a Blockbuster: SNIKT!
by Roderick Allmanson at precisely 09:19
We're getting into the last throes of July, and so the real Blockbuster Season is nearly done with. Every Friday all Summer Long we've been examining the critical, commercial, and cultural potential of each big movie that has hit the Box Office. We're not only concerned with whether or not a film's going to make any money, but whether or not we still be loving it ten or twenty years on down the line. Where is our next Ghostbusters (1984), Back to the Future (1985), or Jurassic Park (1993)? It is interesting enough that these really great Blockbuster films seem to have been canonized, without any new entries allowed. Do the films coming out today have what it takes? What do you say, Wolvie?
Logan took the red pill.
That The Wolverine (2013) exists at all is a strange phenomenon. Wolverine was already basically the star of the first three X-Men movies when he got his own spinoff, X-Men Origins: Wolverine (2009). While that movie did OK at the Box Office, it's also generally accepted as one of the worst superhero flicks of all time, and not just because will.i.am has a major role. The bloated plot made no sense, it butchered longtime fan favourite characters like Deadpool, and it was somehow laced with worse CGI effects than the first X-Men film, which dropped nearly ten years prior. This movie angered me so much, that to date it's still the only film I've ever reviewed that I didn't see in theaters, because I felt so compelled to trash it.
So why am I still kind of jazzed for The Wolverine? It's the kind of experimental movie that can only come from a franchise as experienced as X-Men. By this point X-Men (2000) has almost become the grandaddy of the modern Superhero movie. Out of the three core franchise movies, two are pretty good, and after that they've been free to flex their muscles. After X-Men Origins: Wolverine tried to be a solo flick (which was really just still a team-up pic, crammed with a ridiculous number of mutant cameos), X-Men: First Class (2011) went back in time as the first period super hero film (coming out a few weeks ahead of Captain America: The First Avenger [2011]). Now, the main series is able to mix and mash up its characters in the first time-travelling superhero film in the form of the upcoming X-Men: Days of Future Past (2014). This franchise is able to bend and buckle itself unlike any other modern series of films. So of course we can take a journey to Japan with no A-list supporting cast members, no mutants, and from the looks of it, no powers. Right?
That's why I'm excited about The Wolverine. It's the exact opposite of X-Men Origins: Wolverine. It's a stripped down story focused on character instead of an excuse to have lots of explosions and mindless action. This also makes it a bit harder to market, but it should ultimately pay off. Could it become the greatest X-Men movie out there? The franchise is 3 for 5 on good flicks right now, which isn't too awful. Wolverine as a character is always overexposed, this happens in the comic world, too. Seeing him with a bit of depth and without the Amnesia Monkey on his back is quite refreshing.
Apparently Hugh Jackman is challenging
Matthew McConaughey for the title of
"Most Time Spent on Screen without a Shirt On"
In the best of worlds this will really be an anti-superhero movie. A closed off, contemplative experience that focused on Wolverine dealing with the massive amounts of nonsense he's graced in the previous five films. Or it will just be more of the same crap. If it's the same crap, this film is going to be a drop in the pond, especially during a summer where it has become more and more difficult for any action film to break out. In fact, no action film as really done that well since World War Z (2013), and that only did well by normal standards, not really in terms of how huge its budget was (it's about barely breaking even right now for the studio, once you factor marketing costs and theater takes). To be fair, that was only a month ago, but there has been so many others that have come in, tried, and failed since then, from White House Down (2013) all the way through to R.I.P.D. (2013). I'm feeling like we still need a little breather - here's to Elysium (2013) premiering on a clean slate. If, however, The Wolverine is actually a solid movie, it can rise above a lot of the other crap that has dropped this summer. It can be the movie it needs to be.
There are also two smaller comedies debuting this week. The To-Do List (2013) seems to be an attempt to give Aubrey Plaza a starring vehicle, but I get the sense that she's a much better supporting actress than a lead actress. It also makes me think of this really weird and awkward moment from the MTV Movie Awards a few months back. The To-Do List seems like a fairly typical teen sex comedy, which we haven't seen all that much of lately, to be honest. I'm not sure this can become a cult hit, which it really needs to be if it wants any kind of long term success.
The other comedy film, which is expanding a bit this weekend, The Way, Way Back (2013), does seem to have the makings of a cult hit, which is good. It's got a dream cast of Steve Carell, Toni Collette, Sam Rockwell, Allison Janney, and Maya Rudolph among others. It's also directed by the Oscar winning duo who wrote The Descendants (2011), Nat "Beerfest Germon" Faxon and Jim "Dean Pelton" Rash. It's got kind of an Adventureland (2009) summer growing up movie kind of vibe, and that shit is usually legit, especially with this kind of talent involved. Of course, its marketing has really miffed on this, but if it's solid, it'll find a way into the hearts and minds of the people who want it. Long term, broad success, though, is out of the picture.
So will you be unsheathing your claws this weekend? I feel like The Wolverine has been such an afterthought. This summer was all about Men of Steel and Iron, not Adamantium. We'll see what the pup can pull off. Stay bloodthirsty, my friends.
Labels: Movies, Road to Blockbuster, Summer 2013, X-Men
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Welcome to Norwegian Morning Wood, the peak of technological evolution. You'll find all the movie, television, and music-related pop culture essays and analysis you ever knew you needed. Grab a reuben and prepare to dive.
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FRONTLINE IN THE NEWS
New CDS to assume command
A Change of Command ceremony on 14 January 2021, will see command transfer from General Jonathan Vance to Vice-Admiral Art McDonald as the new Chief of the Defence Staff.
The live-streamed ceremony commences at 2:15 pm on the CAF Facebook page with a Smudging ceremony and opening remarks.
Her Excellency the Right Honourable Julie Payette, Governor General and Commander-in-Chief of Canada, will preside over the ceremony virtually.
The Right Honourable Justin Trudeau, Prime Minister of Canada; the Honourable Harjit Sajjan, Minister of National Defence; and the Honourable Lawrence MacAulay, Minister of Veterans Affairs and Associate Minister of National Defence will also attend virtually.
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BMW and Audi are rounding out their lineups with new plug-in and electric SUVs. Customizable Fiat Centoventi concept could show a replacement for the 500e. And the Nissan Leaf retains its global EV sales lead with 400,000 cars. All this and more on Green Car Reports.
BMW announced that it will sell a plug-in hybrid version of its bestselling X3 SUV next year, in addition to all-electric and gas versions of the car. Called the X3 xDrive30e, it is expected to have as much as 31 miles of electric range.
Audi also showed off its next electric SUV, the e-tron Sportback. On sale in 2020, it will be based on the e-tron quattro, but have a sportier fastback body and potentially sportier driving dynamics.
The modular Fiat Centoventi concept aims to bring fun customization to an electric city car. If Fiat is serious about staying in the U.S. and refreshing its products here it could preview a replacement for the money-losing 500e.
Nissan announced its 400,000th sale of the Leaf worldwide, the first modern electric car. The keeps it in a solid lead ahead of the Tesla Model 3.
Porsche is keeping precisely to its timelines on its Taycan electric car, due in September in Europe.
Finally, Hyundai revealed a redesigned Sonata that could form the basis of new Sonata Hybrids and Plug-in Hybrids.


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The Effects of Statin Medications on Aerobic Exercise Capacity and Training Adaptations
Zsolt Murlasits, Z. Radák
The incidence of myopathy increases dramatically in statin users who also exercise, likely limiting the positive impact of this lifesaving medication. New evidence also indicates that statin use can directly compromise aerobic exercise capacity; however, we are just beginning to understand the interactions of statins with exercise training and adaptations. This review focuses on the interactions of statins with aerobic exercise capacity and training adaptations to summarize the available information and draw attention to the gaps in our current knowledge in this area. PubMed, Web of knowledge, and Google scholar databases were searched between January 2000 and December 2013 using the following terms and their combinations: statins, exercise, aerobic capacity, endurance training, adaptations. The reference lists of the relevant articles were also scanned for additional information. Considering the widespread use of statins and the need for exercise for cardiovascular health, a better understanding of the interactions of these interventions as well as practical solutions are needed to reduce statin adverse effects associated with exercise.
Muscular Diseases
Murlasits, Z., & Radák, Z. (2014). The Effects of Statin Medications on Aerobic Exercise Capacity and Training Adaptations. Sports Medicine, 44(11), 1519-1530. https://doi.org/10.1007/s40279-014-0224-4
The Effects of Statin Medications on Aerobic Exercise Capacity and Training Adaptations. / Murlasits, Zsolt; Radák, Z.
In: Sports Medicine, Vol. 44, No. 11, 01.11.2014, p. 1519-1530.
Murlasits, Z & Radák, Z 2014, 'The Effects of Statin Medications on Aerobic Exercise Capacity and Training Adaptations', Sports Medicine, vol. 44, no. 11, pp. 1519-1530. https://doi.org/10.1007/s40279-014-0224-4
Murlasits Z, Radák Z. The Effects of Statin Medications on Aerobic Exercise Capacity and Training Adaptations. Sports Medicine. 2014 Nov 1;44(11):1519-1530. https://doi.org/10.1007/s40279-014-0224-4
Murlasits, Zsolt ; Radák, Z. / The Effects of Statin Medications on Aerobic Exercise Capacity and Training Adaptations. In: Sports Medicine. 2014 ; Vol. 44, No. 11. pp. 1519-1530.
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abstract = "The incidence of myopathy increases dramatically in statin users who also exercise, likely limiting the positive impact of this lifesaving medication. New evidence also indicates that statin use can directly compromise aerobic exercise capacity; however, we are just beginning to understand the interactions of statins with exercise training and adaptations. This review focuses on the interactions of statins with aerobic exercise capacity and training adaptations to summarize the available information and draw attention to the gaps in our current knowledge in this area. PubMed, Web of knowledge, and Google scholar databases were searched between January 2000 and December 2013 using the following terms and their combinations: statins, exercise, aerobic capacity, endurance training, adaptations. The reference lists of the relevant articles were also scanned for additional information. Considering the widespread use of statins and the need for exercise for cardiovascular health, a better understanding of the interactions of these interventions as well as practical solutions are needed to reduce statin adverse effects associated with exercise.",
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AB - The incidence of myopathy increases dramatically in statin users who also exercise, likely limiting the positive impact of this lifesaving medication. New evidence also indicates that statin use can directly compromise aerobic exercise capacity; however, we are just beginning to understand the interactions of statins with exercise training and adaptations. This review focuses on the interactions of statins with aerobic exercise capacity and training adaptations to summarize the available information and draw attention to the gaps in our current knowledge in this area. PubMed, Web of knowledge, and Google scholar databases were searched between January 2000 and December 2013 using the following terms and their combinations: statins, exercise, aerobic capacity, endurance training, adaptations. The reference lists of the relevant articles were also scanned for additional information. Considering the widespread use of statins and the need for exercise for cardiovascular health, a better understanding of the interactions of these interventions as well as practical solutions are needed to reduce statin adverse effects associated with exercise.
JO - Sports Medicine
JF - Sports Medicine


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Monitoring CTs, PET Scans and MRIs
Home/Managing GIST/Monitoring CTs, PET Scans and MRIs
Monitoring CTs, PET Scans and MRIsJerry Call2019-04-19T12:44:15-04:00
Monitoring is essential after diagnosis and surgery. Monitoring will help watch for recurrence or progression.
It is important to monitor GIST progression through imaging techniques. Magnetic resonance imaging (MRIs), Computed Tomography (CT) scans and Positron emission tomography (PET) scans have roles to play in the long-term surveillance of GIST, as well as determining response to drug treatments.
MRIs, CTs and PETs examined and clarified
Recently, concerns about exposure to radiation during scans have stirred significant discussion in the LRG email community. Although this is a decision that must be made between each individual and their treatment team, it is important to have a strong knowledge base when approaching the issue.
What is an MRI?
MRI stands for magnetic resonance imaging. Using a strong magnetic field, radio waves and acomputer, detailed pictures of tissue, bone and other internal structures are produced.
A doctor may request that a contrast material be utilized during the process; this may be either oral or intravenous. It is possible that an allergic reaction could occur from these substances. Kidney disease may also limit the use of contrast materials. The presence of some metals in the body (such as found in some defibrillators and other implants) may preclude the use of MRI's.
• No exposure to radiation.
• May be able to better characterize and identify abnormalities and other focal lesions.
• May enable the detection of abnormalities that could be obscured by bone in other techniques.
• Contrast materials used in MRI's are less likely to cause a reaction than contrasts used in other imaging techniques.
• Patients that experience claustrophobia may require a sedative.
• Metals can interfere with the quality of the scan.
• Patients must remain perfectly still to ensure high-quality images. Breathing and bowel motion may cause artifacts or distortions when examining the chest, abdomen and pelvis.
• MRI's are more expensive and take longer to perform than other techniques.
What is a CT scan?
Computed Tomography (CT) is a noninvasive test that may be used to diagnose and monitor many diseases. CT scans provide higher quality images of internal organs, tissue and blood vessels than x-rays. Specialized x-ray equipment produces multiple images of the body, called "slices". A computer then joins the images into cross-sectional views that may be printed or viewed on a monitor.
Once again, a contrast material may be used during the procedure. A patient may be asked not to eat or drink anything for several hours before the exam. It is possible for some patients to have an allergic reaction to the contrast material since it contains iodine.
• High quality images may eliminate the need for more invasive testing.
• Images of bone, soft tissue and blood vessels may be produced simultaneously.
• Images are produced quickly and easily.
• Scans can be performed regardless of the presence of any implants.
• CT scans are less expensive than MRI's.
• Scans are less sensitive to movement than MRI's.
• Exposure to radiation, although small, does occur. Cumulative exposure may be a concern.
• Allergic reactions are more common with the contrast materials used in CT scans, however they are still rare.
What is a PET scan?
Positron emission tomography, a PET scan, is a type of nuclear medicine imaging. This means that a small amount of radioactive material (called a radiotracer) is used during the exam. PET scans do not provide pictures or images of structures. The pictures produced by PET scans reflect the levels of chemical activity in different areas. Areas of greater intensity, or hotspots, indicate higher concentrations of the radiotracer and greater chemical activity.
The radioactive material critical for this type of imaging may be swallowed, injected or inhaled. This material collects in specific areas of the body and emits gamma rays, a type of energy. This energy is detected by a special device and a computer producing specialized pictures that demonstrate both function and structure of organs and internal structures.
PET scans measure blood flow, oxygen use and sugar metabolism. In GIST, the measurement of metabolism may provide a gauge of tumor activity or growth or response to treatment. Indolent GISTs may not be visualized accurately on PETs.
• The unique images produced provide information that may not be attainable using other techniques.
• Response to treatment may be measured.
• The use of a radiotracer means exposure to radiation. It takes approximately 24 hours to leave the body.
• Allergic reactions may occur to the radiotracer.
• Diabetics may need to take special care when considering PET scans.
• Scans are time consuming and expensive.
• Resolution may not be as clear as in CTs or MRIs.
• Timing and scheduling are important to ensure accurate results.
The role of CT and PET scans in the evaluation of GIST
In the offices of the Life Raft Group, we receive reports of many CT scans findings that are inconclusive. On a regular basis, scans results are misinterpreted as resistance leading to the premature cessation of imatinib therapy which has the potential to reduce long-term survival. This is of greater concern when the radiologist reading the scans has little experience with GIST or when a patient is not consulting with a GIST specialist. Traditional criteria for the evaluation of tumor resistance are likely to over-diagnose the occurrence of progression. Proper use and interpretation of CT scans is vital for effective GIST treatment. Some experts in GIST imaging are now advocating the routine use of both CT and PET scans for GIST. At the present time however, CT (or MRI) is the recommended imaging method according to the NCCN sarcoma practice guidelines (v.1.2008). The guidelines also state to "Consider PET" and that "PET is not a substitute for a CT." Proper use and interpretation of CT scans is vital for effective GIST treatment. Some experts in GIST imaging are now advocating the routine use of both CT and PET scans for GIST. At the present time however, CT (or MRI) is the recommended imaging method according to the NCCN sarcoma practice guidelines. The guidelines also state to "Consider PET" and that "PET is not a substitute for a CT."
Initial response to therapy
Traditional RECIST criteria diagnose recurrence or progression based on an increase in tumor size or the identification of new lesions, either at the same site as the primary (a local recurrence) or at distant sites (metastases). Although an increase in tumor size is still important for identifying progression in GIST, the appearance of the tumor needs to be evaluated as well.
Frequently, the initial responses of GIST to imatinib therapy do not meet Response Evaluation Criteria in Solid Tumor (RECIST) guidelines for treatment response. GIST tumors may decrease in size slowly or only show a cessation of growth while responding well to treatment. In some cases, tumor size may increase due to hemorrhaging within the tumor, necrosis (tumor cell death) or tumor degeneration. How, then, can treatment success be evaluated?
PET Scans: When available, positron emission tomography (PET), using fluorine-18-fluorodeoxyglucose (18FDG) is an excellent tool for evaluating response. Unfortunately, due to cost and machine availability PET scans are not available to all patients. Alternatives for PET scans will be discussed later in this article.
If a doctor considers using PET to monitor therapy with Gleevec, Sutent or another tyrosine kinase inhibitor, a baseline PET scan should be obtained before the start of treatment. This provides a tool for comparison of future scans, allowing for evaluation of response.
Using PET scans, it is possible to observe responses to imatinib therapy in as little as 24 hours after initiation of treatment. Significant decreases in activity on PET scans can be seen within a month of starting imatinib therapy in patients that are responding to treatment. However, it may take appreciably longer for tumor shrinkage to appear on CT scans even when there is a strong benefit from treatment.
Those patients with primary resistance to imatinib therapy may also be identified using PET scans. These patients may show little to no decrease in activity on a PET scan. At this point it may be advantageous to consider alternatives to imatinib.
CT Scans: Although significant changes in tumor size may not be seen using computed tomography (CT), other changes in tumor characteristics make CT scans valuable in the evaluation of initial response. Tumor density changes may be visible in a single month following the initiation of imatinib therapy in responding tumors. Changes in density have been seen in as little as a single week. In addition to a decrease in tumor density, a decrease in vascularization may be seen. These changes have been shown to strongly correlate to activity reduction on PET scans. In contrast, using size alone may not show positive tumor response. In patients with primary resistance to imatinib therapy, changes in tumor density and vascularization may not appear indicating a need to explore alternative therapies.
GIST liver metastases that are responding to treatment may become more cystic during imatinib treatment and therefore more visible on a CT scan. Some lesions may not be visible on a CT scan prior to initiation of imatinib therapy and appear as they respond to treatment. Care must be taken not to misinterpret these findings as progression and prematurely cease imatinib therapy.
Long-term surveillance of tumor response
Both CT scans and PET scans have roles to play in the long-term surveillance of GIST response to imatinib. Traditional RECIST criteria diagnose recurrence or progression based on an increase in tumor size or the identification of new lesions, either at the same site as the primary (a local recurrence) or at distant sites (metastases). Although an increase in tumor size is still important for identifying progression in GIST, the appearance of the tumor needs to be evaluated as well.
CT scans: As mentioned earlier, it is important to evaluate the density and vascularization of a GIST tumor when evaluating progression. Changes in size without changes in these other tumor characteristics may not indicate progression. In addition, it is possible for a GIST tumor to develop intratumoral (within the tumor) nodules when secondary resistance first begins developing. An intratumoral nodule will appear as change in density and structure.
PET scans: PET scans are very useful for identifying the onset of secondary resistance. When the results of a CT scan are inconclusive or inconsistent with clinical observations, a PET scan may help clarify the situation. When secondary resistance develops, an increase in activity is seen on a PET scan. The use of PET scans may help with early identification of progression as well as prevent misdiagnoses of progression.
Both PET and CT scans are valuable tools in the evaluation and surveillance of GIST. Traditional RECIST criteria may over-diagnose primary resistance and progression. When available, PET scans are an excellent tool for clarifying questionable scans. However, when PET scans are not feasible, evaluation of additional tumor characteristics such as density may help reduce the misdiagnosis of resistance.
Please note that while current practice often involves physicians prescribing more frequent scans up front in a patient's treatment and then tapering off their use later, some prominent clinicians, such as Heikki Joensuu, believe this is not optimal, but instead call for a different frequency of scans. Please click here to see a post that links to an article from Dr. Joensuu that explains this in further detail.
Recent Posts by the LRG
Benjamin RS, Choi H, Macapinlac HA et al. We Should Desist Using RECIST, at Least in GIST, J Clin Oncol 2007;25:1760–1764.
Choi, Haesun. Response Evaluation of Gastrointestinal Stromal Tumors, Oncologist 2008 13: 4-7; doi:10.1634/theoncologist.13-S2-4.
Demetri GD, von Mehren M, Blanke CD et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors, N Engl J Med 2002; 347:472–480.
Van den Abbeele, Annick D. The Lessons of GIST–PET and PET/CT: A New Paradigm for Imaging, Oncologist 2008 13: 8-13; doi:10.1634/theoncologist.13-S2-8, NCCN Sarcoma Practice Guidelines in Oncology – v.1.2008.
Demetri, Benjamin, Blanke, et al., NCCN Task Force Report: Optimal Management of Patients with Gastrointestinal Stromal Tumor (GIST Update of the NCCN Clinical Practice Guidelines, Journal of the National Comprehensive Cancer Network, Volume 5, Supplement 2.
H. Joensuu, et al, Follow-up strategies for patients with gastrointestinal stromal tumour treated with or without adjuvant imatinib after surgery. Eur J Cancer. 2015 May 25. pii: S0959-8049(15)00395-0. doi: 10.1016/j.ejca.2015.05.009.
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Top Tractor Shoot Out: Massey reigns supreme in 2015
By: Jaiden Drought
The Massey Ferguson 7615 Dyna 6 was the clear winner of this year's Top Tractor Shoot Out, despite the calibre of entrants and highly competitive line-up.
There are a number of reasons why the judges unanimously decided on the 7615 as the Top Tractor Shoot Out 2015 winner. We were looking for the best value for money tractor under $140,000 and all things considered, we are convinced this is it.
The Massey Ferguson 7615 Dyna 6 is a good looking, well designed tractor, with many features which we did not take full advantage of on the day. However, there is no doubt that it stood out from the crowd in terms of individual customisation, particularly of transmission and hydraulic settings all combined in a comfortable, well refined cab.
Top Tractor awards 2015
Supreme winner: best value tractor for under $140,000
Best controls
Best innovation
Best serviceability
Best hydraulics
Best equipped
Best dyno closest to rated power
As in every other Top Tractor Shoot Out we have held, the Massey Ferguson entrant has always dyno'd very close to its max rated power and the 7615 did not disappoint, with a healthy 145hp Dyno result. The power comes from the Finnish-made SISU 6.6L, six cylinder four valve engine which is turbo charged, and intercooled. The SISU power plant meets EU legislation Stage 3B (Tier 4i) using SCR with AdBlue.
This impressed all four judges, both in ease of servicing and innovation. Vital parts are more likely to be checked on a daily basis, because it is easy to do so. When coupled with 500hr engine and 1500hr transmission service intervals, this is likely to keep the cost of ownership down.
The Dyna 6 has a user-friendly transmission that gives 24 speeds with six speeds in four ranges. There are a number of different settings for the transmission which are very nifty, although this does take some homework. Having said that, all the automation can be turned off and driven like any other normal semi power shift transmission, all without having to touch the clutch.
User-friendliness
The six pillar cab was well laid out, bright and comfortable. Large wing mirrors aid rear visibility and smaller doors would play less havoc in the wind. You sit high over the top of the bonnet, which slopes away quickly.
The armrest controls in the Massey were very easy to use and, on the outside, a full light package of 12 work lights is standard with six on front, six on back. Adjustable two point cab suspension was fitted to our test machine and, although it wasn't the best there, it did still provide a very comfortable ride.
The key point with the controls on the 7615 is flexibility to suit different applications. An example of this is the transmission, which can be used from four different locations in the cab: the left hand shuttle, the armrest 'T' stick, the joystick or the foot pedal when in auto mode.
The 7615 was equipped with three remotes – two electronic and one manual as standard, although you can go to four spools all electric for an additional $1700 which seems very reasonable.
The 110L/min Closed Centre Load Sensing (CCLS) swash plate pump was not the most powerful there, nor was that power beyond standard (it is optional), but this was the only machine where it was possible to operate the spools individually via the levers mounted externally, directly on the valve block.
With max lift capacity of 8.6T this was by no means tested to its limit on the day. The linkage was well laid out and un-cluttered which made hitching the implements a doddle. The conventional top link holder was cursed at on a number of occasions and, to be honest, it was very good at holding the top link securely when not in use, but was in the road and at risk of being damaged when the top link was in use and at a good height for hitting your head on when hitching implements.
Performance (implements and Dyno)
The low-down design of the Massey – with very little weight above the half-way mark of the rear wheels (which was evident by the large amount of room between the cab and the chassis) – means excellent stability on hills.
The longer wheel base of the six-cylinder machine felt well balanced and definitely aided traction. This machine did have 800-odd-kgs on the nose which helped with the heavy rear kit, although performance was pleasing given it was by no means the biggest hp rated tractor there.
The key thing to remember with this tractor is that while it is neither the cheapest nor the most powerful of our top Tractor Shoot Out line-up, we felt it represented excellent value for money in terms of what the machine offers to a wide range of buyers.
Well laid out cab
Plenty of individual customisation of controls
Four speed pto
Transmission can be controlled from four different locations
Daily servicing has been well thought out
The engine held on very well over a wide pto speed band and never really felt like it was going to drop off the power
Transmission can be driven through all 24 speeds without using the clutch
Only tractor to have electric spools including a joystick with gear and direction changes as standard.
Spools are coloured but there is no corresponding colour on the Dyna-6 joystick
The top link holder is awkward
The doors were very hard to close
Read the full review in issue #217 of Farm Trader magazine. Subscribe here.
2004 MASSEY FERGUSON 6495
1986 MASSEY FERGUSON 265
2000 MASSEY FERGUSON 4235S
MASSEY FERGUSON 6460 MF6460 Dyna 6
MASSEY FERGUSON 7499 DYNA VT
Top Tracter Shoot Out 2015
Six of the best tractors go head-to-head in Farm Trader's annual Top Tractor Shoot Out 2015.
Top Tractor Shoot Out: Case IH Puma 160
When it comes to performance and power, the impressive Case IH Puma 160 was the best of the bunch...
Top Tractor Shoot Out: New Holland T6070 Elite
There is so much to like about this New Holland T6070 Elite. Coming in at just over $116,000, it...


Located in a quiet property just 10 minutes from the centre of Caen, this apartment can welcome 4 to 6 guests.
With the nearby riding club and outdoor school, the apartment is the ideal base for a family keen on equestrian sports.
From your base, you can also set off and discover the many sites of historic Caen, (William the Conqueror's castle, abbeys, museums, Memorial visitor centre...). And the sea is just around 12 miles away.


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Q: Black Screen on Windows 10 Boot, then loads after disk check Recently my Windows 10 startup has been acting strangely.  Sometimes (not all the time) when turned on, it will show the BIOS screen, show the Windows activity symbol, then black screen.  If left alone, after a minute or two it will eventually show the BIOS screen again, then start a disk check.  After this, Windows will load correctly (shows the login screen).  Any idea of why this might happen?
Other things: I am on a desktop, and I had GRUB installed a while ago, but it hasn't had this problem until recently.

A: Seems like Windows is performing a disk check - meaning your drive has bad sectors, Windows is fixing it, than reboot and starting.
I would turn on S.M.A.R.T. reporting (inside BIOS) - that should provide you with a verification for the health of your drive....
It could be caused by some SW, but most likely you are facing a HW failure

redpajama_set_name: RedPajamaStackExchange


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The Shadowgate Warlock Tier is perfect for those that want not only want to experience this new re-imagined Shadowgate but want a ton of extra goodies to go along with it. Everything from an epic soundtrack to a digital calendar and more!
What's in the Warlock Tier?
Everything below is included in the Hero Tier.
Just like the Ranger Tier, you get a Windows or Mac Steam key at a HUGE discount! The game features awesome first-person adventuring through tons of beautifully illustrated rooms, new and updated puzzles, in-game and Steam-based achievements as well as a full, digitally-orchestrated, dynamic soundtrack and a second retro soundtrack featuring Hiroyuki Masuno's original NES composition.
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You'll also receive a 2016 digital wallpaper calendar "The World of Shadowgate" in a good number of resolutions. This 14 month calendar features the wonderful world outside of the castle proper and shows a lot of locations that have yet to be explored in the Shadowgate universe but may very well yet be (hint hint). Note: each illustration has been provided without the calendar for your convenience as well.
The Shadowgate Series of desktop wallpapers feature five of the most iconic locations from within the game – all beautifully painted by master speedpainter Chris Cold, specifically for this re-imagining of the classic first-person fantasy adventure. We've made sure that we gave you a ton of different resolutions so that you can splash Shadowgate on any type of device. And who knows, we mayhave even thrown in a few more because that's how we roll!
What's in the Ranger Tier (Windows/Mac/Linux)?
Where can I buy the iOS (iPad 3 or Newer) version?
© 2019 Zojoi LLC. All rights reserved.


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'Walk together': Nishnawbe Aski Nation signs MOU with 2 municipal social service agencies | CBC News Loaded
'Walk together': Nishnawbe Aski Nation signs MOU with 2 municipal social service agencies
The Nishnawbe Aski Nation (NAN) signed two agreements with municipal social service agencies Wednesday aimed at addressing poverty and homelessness in northern Ontario.
Agreements with Cochrane, Kenora social services boards chart path to fight poverty, homelessness
Cathy Alex · CBC News · Posted: May 09, 2019 8:00 AM ET | Last Updated: May 9, 2019
Nishnawbe Aski Nation Deputy Grand Chief Walter Naveau (centre) and Barry Baltessen, chair of the Kenora District Social Services Board (left) and George Pirie, mayor of Timmins and chair of the Cochrane Social Services Administration Board, pose after signing agreements to work together to address poverty and homelessness. (Nishnawbe Aski Nation )
The memorandums of understanding lay the groundwork for NAN to work in partnership with the Cochrane Social Services Administration Board (CSSAB) in the northeast, and with the Kenora District Services Board in the northwest.
"Sometimes those silent voices out there have no one to advocate, to speak for them," said NAN Deputy Grand Chief Walter Naveau. "When you have an MOU such as we have now, it gives those on the street a voice."
Walk the journey together
Partnering on solutions to social problems such as poverty and homelessness is "truly at the heart of the reconciliation process," said George Pirie, the mayor of Timmins and the CSSAB chair.
"It is imperative that the Cochrane social service agency, and Timmins, participate fully and, in fact, we believe we can lead the way forward and we believe, through working collaboratively with our Indigenous partners that we can be the model of how it gets done."
The intent is to work together from the earliest stages of planning, all the way to implementation and management of any new initiatives that tackle poverty and homelessness.
"We're going to walk together through this journey in the true spirit of truth and reconciliation, that's our desire," said Barry Baltessen, the chair of the KDSB.
Naveau said he believes the signing of the two agreements at the NAN Chiefs Spring Assembly marks a significant step forward.
'Giving hope'
"When we can put our differences aside and not look at the colours, but to look at one another as human beings trying to walk together to make this a different world, a better world," he said. "It's also giving hope."
The signatories believe the MOU will also help them address other social issues, such as mental health and substance abuse and give them a stronger, louder voice when discussing these subjects with the federal and provincial governments.


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Newton student, county chairman, sisters named King Award winners
House struck by lightning, burns
A firefighter talks with the home owner and his child about the search for the family dog. - photo by Robert Porter
Lightning wreaked havoc on Rockdale County last Friday with two residential homes catching ablaze due to strikes, and three more strikes finding its way to the ground.
A house on the corner of Liz Court and Christopher Lane in the Allen's Landing subdivision was struck around 8:15 p.m. and caught fire shortly before 9 p.m.
One nearby resident described seeing a blinding, silent flash of light, and then, about 15 minutes later, smelling smoke in the air.
No one was reportedly at home at the time, but major damage was inflicted in the attic and second floor. There was also water damage and control damage throughout the house.
"There were three gables on the house," said Deputy Fire Chief Mike Lee. "All three had fire on them. It wasn't a matter of getting one spot; we had to put water everywhere."
The house was one of the first built in the subdivision.
Another house in the 900 block of Mt. Zion Rd north of I-20 also caught fire later in the evening. According to Lee, the fire department responded about 10:30 and stayed on scene until about 2:30 a.m.
In total the Rockdale Fire Department had 23 requests for assistance during the storm from 7 p.m. until midnight.
Lee said all units were tied up, and assistance was requested from Newton and DeKalb counties to help answer the calls.
Check back to www.rockdalenews.com for updates.


Adolescent and Young Adult Oncology explores the unique physical, psychosocial, social, emotional, sexual, and financial challenges adolescents and young adults with cancer face. The column is guest edited by Brandon M. Hayes-Lattin, MD, FACP, Associate Professor of Medicine and Medical Director of the Adolescent and Young Adult Oncology Program at the Knight Cancer Institute at Oregon Health and Science University in Portland, Oregon.
The reasons for this disparity in survival rates for AYAs are many and will take myriad approaches on several fronts to solve, including filling the gaps in the clinical and supportive care AYAs receive and the institution of a model of care for AYAs that is distinct from the models used in pediatric and adult medical oncology.
To successfully bridge the gap in oncology care for this patient population, say experts, will require a more patient-focused multidisciplinary approach and a new AYA oncology discipline of care, although more research is needed to determine the most effective comprehensive models of care that incorporate the uniquely diverse needs of AYA cancer survivors, according to Brandon M. Hayes-Lattin, MD, FACP, Associate Professor of Medicine and Medical Director of the Adolescent and Young Adult Oncology Program at the Knight Cancer Institute at Oregon Health and Science University in Portland, Oregon. Dr. Hayes-Lattin is also Guest Editor of The ASCO Post's Adolescent and Young Adult Oncology column.
The ASCO Post talked with Dr. Hayes-Lattin about the gaps in oncology care for adolescent and young adult cancer survivors and how to fill those gaps to improve oncology care for this patient population and increase their survival rates.
Contributing factors to the worse outcomes for AYA survivors include a limited understanding of age-related differences in tumor biology, less adherence to prescribed therapy, delayed access to care, and lower participation rates in clinical trials. Are there other reasons why AYAs don't fare as well as younger and older adult patients?
The short answer is we don't know all the reasons for the differences in survival improvements for young adults compared to pediatric and older patients, but it probably is a combination of multiple factors, including the ones you listed. The biology of the disease in either older patients with a pediatric-type cancer or younger patients with an older adult–type cancer may well be different. And there are some pretty clear-cut examples of that.
It's probably a big mix of things that are making the difference in survival rates in AYA patients. The real challenge for the oncology field is to sort out which of these components of care are the most important in survival disparity and whether they vary by disease so that we can design novel programs that would fix the problem.
For example, young adult patients with acute lymphoblastic leukemia (ALL) more often present with poorer prognostic molecular or clinical features than children with ALL, and the same thing is true on the other end of the age spectrum: Young women with breast cancer more often present with histologic or endocrine features that put them in a poor prognostic group than older patients with the disease.
In addition to differences in biology, there are retrospective data showing that AYA patients with Ewing sarcoma, for example, who receive the same treatment as children with the same cancer, have different survival rates depending on whether they receive treatment in a pediatric or an adult cancer facility. There are also differences in the delivery of therapy between pediatric and adult hospital environments. Whether that has to do with the actual treatment regimen that is used or the ability of the adult cancer facility to help AYA patients not only adhere to treatment but give them appropriate follow-up care is unclear.
So it's probably a big mix of things that are making the difference in survival rates in AYA patients. The real challenge for the oncology field is to sort out which of these components of care are the most important in survival disparity and whether they vary by disease so that we can design novel programs that would fix the problem.
Please talk about some of the unique characteristics of AYAs that may make them more complicated to care for than pediatric or older adult patients, such as their different levels of maturity and independence from parents; education, career, and personal relationship goals; and fertility and sexual concerns.
You are hitting on the highlights of what makes caring for AYAs different and challenging. I would sum up the issue as how utterly impactful a cancer diagnosis is in young adulthood. It is so disruptive to the normal developmental milestones of young adults, including establishing independence from parents, establishing a career, and starting a family, and interfering with these milestones can be devastating.
A young child with cancer is still under parental care and hasn't launched into these independent transitions yet. These transitions may be delayed, but cancer has not fundamentally disrupted the process, as it does for a young adult. And while an older patient may have a career crisis when he or she gets a cancer diagnosis, most likely the person has a career track record to fall back on and can reengage in the workforce once treatment is completed.
Having your education or career interrupted when you are a young adult is so much more disruptive and life-altering. To me, that is the core difference between caring for pediatric and older adult patients and adolescent and young adult patients.
How can the medical care gap between pediatric and older adult patients and AYA patients be bridged? What are the issues and the solutions?
Much of what is being discussed as potential causes and solutions to these problems is still hypothesis-driven, but there may be structural differences in the care-delivery system that are causing the disparity in survival rates. For example, the ratio of providers to patients tends to differ dramatically between the pediatric and adult cancer worlds, with the adult world often having fewer providers per patient than the pediatric world. The relatively greater availability of physicians, nurses, social workers, and other staff in a pediatric setting might be one structural difference that could explain how much support is available to AYAs and their caregivers to help them adhere to follow-up appointments and treatments.
Before we can say that with certainty, however, we need to investigate how strong the association is. For example, it may be true that there are larger numbers of staff caring for pediatric patients, but that alone may not be responsible for the survival differences. If that is the case, we shouldn't be arguing for hiring more staff, because the problem may be differences in tumor biology instead.
The same is true for the other potential causes of survival disparity, such as treatment protocols for the different age groups. We need rigorous testing before we can know the answer. We are beginning to do such work in ALL, where we are evaluating pediatric-based treatment vs adult regimens in ALL patients up to age 40. It is not a randomized trial, so it is not the most rigorous way to answer this question, but it is a first step into that line of investigation.
Again, if it turns out that the treatment difference can be shown to have an impact on survival, then we will have the necessary tools to make a change. What's challenging is that this kind of work takes time and patience.
AYAs are generally not well represented in clinical trials. Is it because they are not being offered clinical trials or because they are not interested in participating in clinical trials?
This is another area that is under study, but it appears that AYAs are more often treated in community care settings, where there aren't many clinical trial opportunities. For example, it is much more likely that a pediatric cancer patient is being cared for in an academic center, where there are many clinical trials available and where providers place a high priority on enrollment in clinical trials. An older patient is more likely to be treated in a community oncology practice, where the availability of clinical trials might be more limited and internal motivations to enroll in clinical trials are not the same.
There are different models of care used in pediatric oncology, which is more family-focused, and adult medical oncology, which is more disease-focused. Which model of care do you think would most benefit AYA patients?
I struggle to answer that question because, again, without hard evidence-based data to inform decisions about an appropriate care model for AYAs that takes into account tolerance to treatment, tumor biology, and psychosocial development, it is difficult to say what type of care model would bridge the gap in oncology care and make a difference in survival outcome.
We now have several initiatives to create AYA services that are very different from each other because they are not informed by a robust database of information, and that makes it difficult to proceed in one direction. As a result, the programs that get prioritized or funded are not necessarily the ones we know are going to have the biggest impact. But following the progress of these new models will allow us to answer these questions in the future.
Currently, do AYAs fall mainly into the more disease-focused model of care?
In most cancer centers, that is true—even for those that are in various stages of developing programs suited more to the needs of AYAs. Most of the time, the primary care of AYAs is based on disease-focused care, as opposed to having an oncology team expert in all AYA cancer types taking care of this patient population regardless of cancer type.
Most cancer centers have chosen to treat AYA patients with a diseased-based model of care and then bring AYA-type resources to that care, which might include novel collaborations. For example, acute leukemia medical teams on the pediatric and adult cancer service might choose to work together and jointly open trials for pediatric and AYA patients, while truly coordinating their care across the adult/pediatric setting, even though they are still functioning within a disease group. Or it may be that a breast cancer clinic has a list of providers with a special interest and expertise in young women with the disease, so even though the care is disease-based, it brings some AYA consideration to that disease-based team.
Do programs like Teen Cancer America, which provide specialized facilities in cancer centers for teens and young adults (see "Bridging the Gap Between Pediatric and Adult Oncology Care," in the October 10, 2015, issue of The ASCO Post), help AYAs feel more comfortable during treatment and improve adherence to follow-up appointments after treatment is completed?
Disclosure: Dr. Hayes-Lattin reported no potential conflicts of interest.
1. American Cancer Society: Cancer Treatment & Survivorship Facts & Figures 2016-2017. Available at www.cancer.org/acs/groups/content/@research/documents/document/acspc-048074.pdf. Accessed November 28, 2016.
2. Bleyer A, O'Leary M, Ries LAG, et al: Cancer Epidemiology in Older Adolescents and Young Adults 15 to 29 Years of Age, Including SEER Incidence and Survival: 1975-2000. NIH pub no 06-5767. Bethesda, Maryland; National Cancer Institute; 2006.


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Beauvais je město v severní Francii (Picardie) asi 90 km severně od Paříže. Je to hlavní město departementu Oise se slavnou katedrálou, která je na Seznamu světového dědictví UNESCO, a dalšími památkami. V roce 2011 zde žilo 54 189 obyvatel.

Historie
V římské době se Beauvais nazývalo Caesaromagus a roku 325 navštívil město císař Konstantin Veliký. Současný název je odvozen od galského kmene Beilovaci, kteří zde měli hlavní sídlo. V 9. století vzniklo hrabství Beauvais a roku 1013 bylo založeno biskupství. Za stoleté války obléhali město roku 1346 a znovu 1433 Angličané. Roku 1472 je obléhal burgundský hrabě a město se proslavilo hrdinskou obranou pod vedením Jeanne Hachette, která má u radnice pomník. Její památka se každoročně slaví koncem června.

Hospodářství a doprava
Beauvais mělo slavnou manufakturu na výrobu koberců, dnes je zde velký závod AGCO, který vyrábí traktory Massey-Ferguson.

Beauvais leží nedaleko dálnice A 16 a má pravidelné přímé železniční spojení do Paříže. V blízkosti leží mezinárodní letiště Beauvais-Tillé, kam létají hlavně levné aerolinie. Z letiště je pravidelné autobusové spojení do Paříže.

Pamětihodnosti
 Katedrála sv. Petra z let 1225–1275 leží v severozápadní části historického města. Není sice dostavěná, má pouze chór a křížovou loď, s výškou klenby asi 48,5 m je to však nejvyšší gotická katedrála vůbec.
 V západním sousedství katedrály je prostý karolinský kostelík z 9. století.
 V jejím sousedství je také biskupský palác ze 16. století se dvěma věžemi, postavený zčásti na galsko-římských základech. Dnes je to sídlo muzea departementu Oise.
 V jižní části historického města, nedaleko nádraží, je středověký kostel sv. Štěpána s románskou lodí, pozdně gotickým vysokým chórem a zajímavou věží v průčelí. Kostel má zajímavá barevná okna z 15. a 16. století.

Galerie

Sousední obce
Allonne, Aux Marais, Fouquenies, Goincourt, Le Mont-Saint-Adrien, Saint-Martin-le-Nœud, Therdonne, Tillé, Troissereux

Vývoj počtu obyvatel
Počet obyvatel

Osobnosti
 Svatý Geremarus (†658), mnich, opat a poustevník
 Jean Racine (1639–1699), dramatik
 Jean-Baptiste Dubos (1670–1742), estetik a historik
 Alfred Des Cloizeaux (1817–1897), mineralog
 Félix Faure (1841–1899), politik a prezident
 Henri Léon Lebesgue (1875–1941), matematik
 Hubert de Givenchy (1927–2018), aristokrat, módní návrhář, kostýmní výtvarník a návrhář kosmetiky
 Jean-Claude Decaux (* 1937), zakladatel JCDecaux, společnosti podnikající v oblasti outdoorové reklamy

Partnerská města
  Dej, Rumunsko, 1995
  Maidstone, Spojené království, 1961
  Setúbal, Portugalsko, 1982
  Tczew, Polsko, 2003
  Witten, Německo, 1975

Odkazy

Reference

Související články
 Seznam obcí v departementu Oise

Externí odkazy

 Oficiální stránky města

Města v Hauts-de-France
Obce v departementu Oise
Města vyznamenaná Řádem čestné legie
Francouzské prefektury

redpajama_set_name: RedPajamaWikipedia


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text:
by Maariyaah Shaheen April 16, 2017, 9:52 pm in Culture & Art
You Will Not Believe How Beautiful These 5 Mosques Are
Painstakingly detailed, luxuriously defined, it's the hands and minds of Islamic architects and artists that have built the most beautiful and auric places to ever exist. From the depths of the Middle East to the European borders, the spread of the Islamic Empire has laid its long lasting effects on the culture and art of these places, so clear from the offset. The success of Islamic architects in times before ours, celebrates the success of their achievements, raising the bar for our own. But before we take it upon ourselves to question our success, let us all take a couple of minutes to embrace the geometric artistry of Islamic architecture.
1. Jameh Mosque of Isfahān, Isfahān, Iran
© Ali KoRdZaDeh
A living architectural documentary, the Jameh Mosque of Isfahan in Iran is of the only mosque in the country that continued to be built from the 7th to the 20th Century, embodying political exigencies and the luxurious taste of the Islamic Empire of Persia.
2. Hassan II Mosque, Casablanca, Morocco
© Nasbe Photography
© Nabil Elminaoui
Completed in 1993, a more recent architectual advance, this mosque seems fantisical, almost unreal. It's positioning on the coast of the Atlantic ocean and recorded to be the largest mosque in Africa. It also possesses the tallest minaret in the world.
3. Nasir Al-Mulk Mosque, Shiraz, Iran
© Mohammad Reza Domiri Ganji
© Amin Abedini
© Omid Jafarnezhad
It's the colour. The metaphorical symbolism is unmissable, neither is the breath-taking feeling when in this mosque. If you find yourself in the early mornings, you'll be sure what I am talking about. With a significant architectural history from the Islamic Empire of Persia, this mosque holds both architectural and historical significance.
4. The Blue Mosque, Istanbul
An architectual beauty in the heart of the Islamic Empire, The Blue Mosque is almost opposite one of the seven wonders of the world, the Hagia Sophia. What makes this mosque stand out is the sense of community. Despite the elegance and success of beauty in this mosque, it does not fail to hold a great sense of community with both locals and tourists alike, sermons in various languages as well as the prominent celebration of Jumuah.
5. Badshahi Mosque of Lahore, Pakistan
© Genevieve Hathaway
Commissioned by the Sixth Moghul Emperor in the 1671, The Badshahi Mosque integrates the Middle Eastern and Asian architectural inspiration to construct the second largest mosque in Asia. This mosque certainly doesn't fail at accentuating sheer passion, beauty, grandeur and architectural excellence of the Moghul rule.
architectureinspiringIranIstanbulMoroccomosquePakistanTurkey
Written by Maariyaah Shaheen
Maariyaah Shaheen is an academic and islamic studies student. She is the Founder of SisterHoodUK and runs Youth activities in her spare time. Aspiring to make a change, she's currently looking out for ways of improving her chocolate cake recipe and aiding the Ummah but not simultaneously. A dedicated #STEMinist (like a feminist but cooler).
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Next article 23 Things You're Tired of Hearing as a Muslim
Inspired By a Bedouin's Tent: The Faisal Mosque in Islamabad Was Designed By a Turkish Architect
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Discovering the Beauty of Architecture: 5 Beautiful Pieces of Islamic Architecture Around the World
One For the Architecture Lovers: Soon You'll Be Able to Pray in a Wooden Mosque in Cambridge
An Underground Mosque?! This Turkish Mosque Was Building of The Year 2015 at the World Architecture Festival
A Piece of Art: Impressive Mosque in Riyadh Combines Contemporary and Traditional Elements


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Object is supported only in FT-SINIX. The poll interval is the time in minutes between poll actions for verifying whether FT has been stopped, in order to send an ftStopTrap. The value 0 (zero) means: no polling. Default: 0 Reading: Informs poll interval. Writing: Sets poll interval.


140 projects in result set. Displaying 20 per page. Projects sorted by activity ranking.
3. Korean R Translation Repository - The R Documentation files are licensed under the GPL, version 2 or 3. This means that the pilot project to translate them into Korean has permission to reproduce them and translate them.
6. cran2deb - debianize CRAN - cran2deb automatically converts CRAN packages for R into Debian packages, handling dependency matching and package updates nicely.
7. Marketing Analytics Repository - The Marketing Analysis Repository is a project that aims to bring quantitative Marketing and R together. For example, by developing an R package that supports typical analysis and decision tasks.
8. Hierarchical Generalized Linear Models - The aim of the project is to develop a series of packages, including the hglm package, which implement the estimation algorithm of different random effects models based on the hierarchical likelihood theory.
9. Composite Likelihood for Random Fields - Composite-Likelihood based methods for Random Fields.
11. spsextante - R to Sextante interface - Provides a suite of geospatial analysis tools by connecting R with the Sextante geograrphical information system (www.sextantegis.com), similar to spgrass6 and RSAGA.
15. mixOmics - mixOmics is an R package that supplies different methodologies to unravel relationships between two heterogeneous data sets of size n × p and n × q where the p and q variables are measured on the same samples or individuals n.
17. Easy database interface - Simple database interface for SQLite, MySQL and MS Access. It provides functions for easily reading, writing, listing and subsetting tables in SQLite, MySQL and MS Access. easydb is build on top of RSQLite and RODBC.
18. factorplot - factorplot provides numerical and graphical summaries of factor-level differences in GLMs. It produces all pairwise hypotheses tests with either the exact pairwise difference and variance or user-supplied quasi-variances or floating absolute risks.
19. mzmatch.R - This package provides integration between the mzMatch/PeakML Java library (and its file formats) and the XCMS library for R. mzMatch is a modular, open source and platform independent data processing pipeline for metabolomics LC/MS data.


text:
CIA chief Pompeo 'declares war on free speech' – Assange
26 Apr, 2017 05:05
WikiLeaks founder Julian Assange. © Neil Hall © Reuters
Julian Assange has accused Mike Pompeo of declaring war on free speech while seeking vengeance for the exposure of CIA's dirty secrets and backtracking on his earlier stated admiration of WikiLeaks' work until it turned against his personally.
"The 'Pompeo doctrine' articulated in his speech ensnares all serious news and investigative human rights organizations, from ProPublica to Amnesty International to Human Rights Watch," Julian Assange wrote in an opinion column published in the Washington Post, responding to the CIA chief's remarks earlier this month.
'All sorts of illegal actions by CIA': Assange blasts Pompeo for 'pre-emptive attack' on WikiLeaks
Speaking at the Center for Strategic and International Studies on April 13, Pompeo went on the warpath against WikiLeaks – the whistleblowing website – accusing its editor of being on the "wrong side of history" and seeking to harm America, freedom, and democracy.
Firing back at the CIA director, Assange explained that Pompeo is distracting attention and seeking vengeance for the release of the Vault 7 series of documents that WikiLeaks began to publish on March 7. The documents detail the activities and capabilities of the CIA to perform electronic surveillance and conduct cyber warfare.
"All this speech to stifle speech comes in reaction to the first publication in the start of WikiLeaks' 'Vault 7' series," Assange wrote, adding that "when the director of the CIA, an unelected public servant, publicly demonizes a publisher such as WikiLeaks as a 'fraud,' 'coward' and 'enemy,' it puts all journalists on notice, or should."
Assange also stressed that Pompeo's labeling of WikiLeaks as a "non-state hostile intelligence service," lacks any facts and called it a "dagger" aimed at the US constitutional right "to receive honest information about their government."
New Op Ed by me: CIA declares right to target media and human rights groups with "Pompeo Doctrine" https://t.co/6NcRJFYcLo
— Julian Assange (@JulianAssange) April 26, 2017
Calling WikiLeaks an intelligence agency would be "as absurd as the suggestion that the CIA is a media outlet. Both journalists and intelligence agencies cultivate and protect sources, collect information and write reports, but the similarities end there," Assange added.
WikiLeaks 'hostile intel,' Assange & his followers 'demons': CIA chief goes ballistic
Assange also directly addressed Pompeo's comments that he (Assange) and "his ilk make common cause with dictators." Calling the CIA Director's comment ironic, Assange noted that the agency's pursuit to silence US government opponents places him in line with dictatorial regimes.
"Pompeo finds himself in the unsavory company of Recep Tayyip Erdogan of Turkey (257,934 documents published by WikiLeaks); Bashar al-Assad of Syria (2.3 million documents); and the dictatorship in Saudi Arabia (122,609 documents), to name just a few who have tried and failed to censor WikiLeaks," Assange wrote in the Washington Post.
The Australian, who has taken refuge from US prosecution in the Ecuadorian embassy in London, reminded readers that Pompeo was once a WikiLeaks fan.
"Pompeo liked WikiLeaks when he perceived it was publishing material revealing the shortcomings of his political rivals. It was only when our publications touched Pompeo's rice bowl that WikiLeaks became his target," Assange said.
Trends:WikiLeaks news


Silverwood products have been designed by cooks with cooks in mind. The Silverwood company has been producing bakeware products since 1966 with one specialty: high quality, long-lasting products to combat the rise of cheap, shoddy bakeware. Amateur and professional bakers have lauded the range of Silverwood products for their long-lasting, durable cake pans and baking tins. Made from durable, silver-anodised aluminium alloy which is a good heat conductor, heat distributes evenly during baking and reduces baking times. This produces a nicer bake and more importantly they are also easier to clean. The loose base allows for the cake to easily slide out, and we love that the tin is completely warp-resistant and improves with each use.


text:
Q: How to make a popup to select an item using the Sonata lists I recently started a project using Symfony, and as a part of it, there is a Sonata (modeled) backoffice. I love the way Sonata make that lists of items where you can search / filter or wathever.. So, the question is:
Can I reuse this lists as a popup for example to select a user of my DB?
The example is easy:

*

*I have a user table on my DB

*I have a form where you can select a user in one input but, there is 10.000 in the DB so a select is not an option.

*I'd love to use the user list of my sonata project in a popup and when the client click on a user of the list I would put it on the base form.

Is that possible? Is there a way for that?

A: Yes, you can do that using sonata_type_model_list as your field type.
You can see some examples of it here
Note that for a large dataset this is pretty useless unless you add some filters to it as well, otherwise it's just a huge paginated list.

A: Finally I did it creating new Admins with this fields inside:
protected $baseRouteName = 'admin_product_clean_list';
protected $baseRoutePattern = 'product-clean';

I also override the getTemplate method to use my clean custom layout like this:
public function getTemplate($name)
{
    switch ($name) {
        case 'layout':
            return 'DemoBundle:admin:onlytable_layout.html.twig';
            break;
        default:
            return parent::getTemplate($name);
            break;
    }
}

An then just use it with URLs like this:
"{{ app.request.getBaseURL() }}/admin/product-clean/list"

Not sure if it is the best way but it works like a charm.. I can use my custom layout copied of sonata's project (vendor/sonata-project/admin-bundle/Resources/views/standard_layout.html.twig) and remove or add whatever I want. You can also use the sonata empty or ajax layouts instead.