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Puyol apologises for "clumsy joke" after replying to Casillas "I'm gay" tweet
Carles Puyol has moved to apologise for his reply to Iker Casillas, after the former Real Madrid goalkeeper tweeted that he was gay.
The Spanish keeper deleted the tweet and claimed he had been hacked, but not before Carles Puyol engaged with him on social media and joked about their relationship.
The Barcelona legend then replied: "The time has come to tell our story, Iker" with pictures of them celebrating together.
It saw Puyol and Casillas come in for criticism and the former has since apologised for any hurt he caused. The former defender said: "I have made a mistake. Sorry for a clumsy joke with no bad intentions and totally out of place. I understand that it may have hurt sensitivities. All my respect and support for the LGTBIQA+ community."
Casillas too has had to clarify his comments, having said: "I hope you respect me: I'm gay," on social media. He later deleted his tweet and said: "Hacked account. Luckily everything in order. Apologies to all my followers. And of course, more apologies to the LGBT community."
Josh Cavallo, an Australian player who came out as gay last October, is among those to slam the duo who made light of the situation on social media.
He said: "Iker Casillas and Carles Puyol joking and making fun out of coming out in football is disappointing. It's a difficult journey that any LGBTQ+ ppl have to go through. To see my role models and legends of the game make fun out of coming out and my community is beyond disrespectful."
Why Liverpool were not awarded a penalty vs Arsenal for Gabriel's handball
Cavallo's post was shared by Jake Daniels, the Blackpool star who became the first current player in the UK to come out as gay since Justin Fashanu in 1990 when he made the announcement in May.
Former Liverpool player Jose Enrique also slammed his fellow Spaniard, saying on social media: "Instead of apologize and recognize the mistake rather lie to everyone."
Reports in Spain claimed that Casillas was frustrated by speculation surrounding his dating life. AS claimed that Casillas' post was a response to rumours regarding a new relationship with Alejandra Onieva – 18 months after separating from Sara Carbonero, the mother of his two children.
Casillas called time on his playing career in 2020 after a successful career that lasted more than two decades. He came through the ranks at Real Madrid and established himself as their No.1 at a young age.
His career at the club saw him make 725 appearances. During that period he won three UEFA Champions League titles, starting in their La Decima win of 2014. He also won 167 caps over a 16-year period with his country.
Posted in Trending, La LigaTagged #Carles Puyol #Iker Casillas
Zinchenko's incredible reaction to Bukayo Saka's winning goal for Arsenal
Oleksandr Zinchenko summed up the feelings of every Arsenal fan with his incredible reaction to Bukayo Saka's late penalty which secured a 3-2 win over Liverpool. The Gunners had failed to win in their last five games with Jurgen Klopp's side – in fact, they had failed to score and […]
Eden Hazard names his toughest ever Premier League opponent
Griezmann: I'm on the same level as Messi and Ronaldo
Ousmane Dembele responds to Liverpool's transfer offer
Simeone reveals why Atletico Madrid beat Liverpool before even getting to stadium
Sevilla explain why Man Utd were not getting Anthony Martial at his best
Mohamed Salah responds to Real Madrid transfer rumours


See the Traffic Calming Guidelines HERE.
Quechee Covered Bridge Replacement Presented by: Evan P. Detrick, P.E., DuBois & King, Inc.
Active Risk Management for the Charles River Basin ABP Presented by: GeoComp Corporation and Vanasse Hangen Brustlin, Inc.


"Linux gives you a world of choices, from the applications you run to the desktop environment you use, and you start making those choices before you even install it, by selecting a distribution to install. The distribution you choose defines how you'll install your Linux system, how you'll manage it on an ongoing basis, and how you can expand the base system with new software installations.
"Unfortunately, there's no one distribution that's perfect for anyone, but how could there ever be? Different users have different needs, and Linux is all about letting you do what you want, rather than being shoehorned into someone else's idea of a good system. So how do you pick the right distro for you?


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Elliot Balchin (born 30 June 1990) is a British actor who has had roles in various British television series.

Early life and career
In 1999, Balchin joined a Nottingham drama workshop run by ITV and remained for ten years. From 2006 until 2009 he also participated in the National Theatre Connections scheme. In 2009 he began a three-year acting course at LAMDA.

In 2002, he secured a stage role in Ethel and Ernest at the Nottingham Playhouse. Balchin has had roles in the BBC medical shows Doctors and Casualty plus the ITV dramas Bernard's Watch and Peak Practice. In 2008, he appeared in the short film titled Lamb playing Johnny.

In January 2013, Balchin tweeted that he had joined the cast of Channel 4 soap opera Hollyoaks. It was later confirmed that he would play the role of Kevin Foster. On 20 August 2013, Balchin revealed that he would be returning to Hollyoaks for a guest appearance. In 2017, Balchin played Private Peters in the film Journey's End. In 2018, Balchin appeared in Holby City the episode "Family Ties" as Dan Chambers. In 2020, Balchin appeared as Leather Jacket in the British film Solitary. In 2021, Balchin appeared in the film Off Your Head. Balchin also played Frank Sprague in an episode of The Engineering That Built The World.

Filmography

Sources:

References

External links

Living people
21st-century British male actors
British male television actors
British male film actors
1990 births

redpajama_set_name: RedPajamaWikipedia


Razers enter the Smartphone Arena with Razer phone which is aimed to offer you the performance of a gaming laptop in a smartphone.
As we have previously told you about the Razer preparing a Smartphone especially for Gamers, finally the day has arrived where Razer has introduced its first Flagship Smartphone that too specially designed for Gamers in you.
Razer is known for high-performance gaming hardware, software, and systems, probably famous for their Gaming laptops & Accessories. Razer previously acquired Nextbit, makers of the cloud phone which have helped Razer to craft the new sensational Gaming Smartphone.
It features a 5.7" QHD IGZO screen is the World's first smartphone with a 120Hz refresh rate to be known as Ultramotion Display like Razer said, there is no tearing, and no buffering, all smooth gaming experience. The display is protected by Gorilla Glass 3.
The Razer Smartphone Integrated with the best available Flagship processor which is a Qualcomm's Snapdragon 835 with the mammoth 8GB of Ram and 64GB Internal Memory which is expandable via a microSD card.
"We leveraged our engineering experience from laptops creating a heat pipe and two layers of thermal shielding, turning the structure of the phone into a heat sync, so you can use your phone in the high-performance mode for a lot longer and avoid throttling," says Moss.
For the photographer in you, there is a 12Mp Dual Camera, where one is a 12MP F/1.75 wide angle lens and the other is a 12MP F/2.6 telephoto lens with 2X zoom. Additionally, you'll get portrait mode and seamless zoom features in it. The front camera is consists of 8MP F/2.2 sensor.
You won't be disappointed if you want seemingless gaming in your Smartphone because Razer Smartphone packs a 4,000mAh battery that make sure you doesn't end your Gaming session without completing your Mission. It also comes with support for Quick Charge 4.0+, making it the first phone to ship with the new fast-charging technology. What actually it will do, is that it will charge your device from 0 to 85% in just 1 hour.
The Razer Smartphone comes with big Dual Front facing Speaker covering the front of the Smartphone. Razer says, The speakers have dedicated amplifiers, Dolby Atmos, and are certified by THX, another of Razer's acquisitions.
There is a fingerprint scanner embedded in its power button and a USB-C port at the bottom. It also has NFC but no headphone jack. The Razer Phone runs Android 7.1.1 Nougat out of the box with a custom Razer version thanks to Nova Launcher Prime.
What's in it for gamers?
Razer phone has a library of specially designed games that take advantage of its Ultramotion Display. Some of the games were launched in the event were Arena of Valor – let just skip it until you are a Clash of Clans lovers, Tekken – ya quite popular and yet entertaining Game, Final Fantasy XV – not that good especially with those graphics. A brand new game called Ultra Hunt was also demoed at the launch and more game to come in future.
All this you'll get in Razer Smartphone for just $699 not so expensive to taste a better Smartphone. The Pre-orders already begin today and it will start shipping 17th of November. It will be exclusive to Microsoft Stores in the US and Canada, and Three Network in Europe.


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A by-election was held for the Australian House of Representatives seat of Corangamite on 29 August 1953. This was triggered by the death of Liberal MP Allan McDonald. A by-election for the seat of Lang was held on the same day.

The by-election was won by Liberal candidate Dan Mackinnon, who had previously served as the member for Wannon from 1949 to 1951.

Results

References

1953 elections in Australia
Victorian federal by-elections
1950s in Victoria (Australia)


Parties are fun and easy. Party room holds up to 25. Book early. Our room is popular and can be booked solid for weeks ahead.
Click on "Book Online" to check availability or call 243-0886 and ask for assistance.
Costs: The party room rental is just $35 plus tax, due at the time of booking. At the party you just pay for the price of the individual pieces painted by each person at the party. You control the cost. The pieces are packaged together and delivered to the party host. We have a refrigerator and freezer available for your convenience.
Adult mixers are a BLAST at Angelo's. Check out our "Gather with Friends" option. Close out the world and "hang out" with your friends. Bring in the refreshments, beverages, and company. You get the privacy of our party room for 2 hours.
Having an Angelo's pottery party at home is fun and easy. We can accommodate any size group -- large or small.
For the cost of the pottery pieces, you can take them home, let your guests paint, play, and party and then bring the pottery back for us to fire. We will provide a to-go kit with paint, brushes, palettes, and of course, pottery that you have chosen in advance.
You can add a memory plate for $20 or upgrade the memory piece to a picture frame or Piggy Bank for an additional fee. The party piece is then decorated and personalized by our artists.
You have complete control over your spending this way. Your guests have only the choices that you deliver to them at home.
The pieces are packaged together 1 week after the party and picked up by the party host.
Business Groups: We can bring pieces and paint and an artist to your business or workplace and provide a painting experience that helps people bond, relax, and build relationships.
You can rent our entire studio for $100 per hour. Bring in as many as 100 people and we will provide staffing and instruction. We can close the studio during the weekday evenings or you can choose a time after our regular operating hours.
Bring in food and drink or have it catered by a third party. The party room can be used as a feast center.
You can pay for all items on one ticket or we can individually ticket your guests. Just let us know what you want. If you have a theme, let us know at least 2 weeks in advance and we will order in especially for you.


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Keywords: BMPs, gestational diabetes mellitus, heart
Ghasemzadeh F, Golalipour M, Haidari K, Nazari Z, Golalipour MJ. Gestational diabetes influences bone morphogenic protein signaling during heart development in C57BL mice. J Anat Soc India 2021;70:197-201
Ghasemzadeh F, Golalipour M, Haidari K, Nazari Z, Golalipour MJ. Gestational diabetes influences bone morphogenic protein signaling during heart development in C57BL mice. J Anat Soc India [serial online] 2021 [cited 2022 Jan 21];70:197-201. Available from: https://www.jasi.org.in/text.asp?2021/70/4/197/333192
Gestational diabetes mellitus (GDM), a type of Diabetes mellitus, affects approximately 7% of pregnant women, which is characterized by an impaired glucose tolerance during pregnancy.[1]
On the other hand, Bone morphogenetic proteins (BMPs), a family of Transforming growth factor (TGF-βs) superfamily, is a heterodimer complex consisting of type I and II serine-threonine kinases and signals through the SMAD and non-SMAD pathways.[2],[3],[4] BMP involves in some developmental processes homeostasis of tissues.[5] BMPs are essential and play a main role in the formation of mesoderm, particularly myocardial development.[6] van Gelder et al., a study has indicated that gestational diabetes is associated with an increased risk of prenatal mortality and major congenital anomaly.[7] Some of the population-based studies have reported that the infants of diabetic mothers are more susceptible to complex diseases, including obesity, metabolic and cardiovascular complications during childhood and adolescence.[8],[9] It has been proven that children of mothers with GDM have more complex congenital heart anomalies and it seems that, hyperglycemia is a risk factor that has adverse impacts on the development of the cardiovascular system.[10],[11]There are few articles about the molecular mechanisms of congenital cardiovascular malformation due to gestational diabetes.
BMPs have crucial roles in cell proliferation, differentiation, migration, and apoptosis during organ development and adult life. As their inductive roles cardiac differentiation heart morphogenesis. Also, BMPs are pivotal in the regulation of septovalvular development during the formation of heart chambers. In the heart tissue, some of BMPs are expressed before cardioblast and throughout the later stages of heart development. It has been clear that the main roles of six BMPs (BMP 2, 4, 5, 6, 7, and 10) are expressed in the heart during development.[6]
Despite an understanding of the effects of BMPs on cardiac development, but we were wondering whether GDM has any impacts on the expression of BMPs during development.
On days 7.5 and 8.5, the BMP2 level is prominent on day 7.5 in cardiac crescent pro-myocardium and around mesoderm cells, while lower levels are in the outflow tract on day 9.5. The BMP2 expression in the AV channel is turned off on day 10.5.[12] BMP4 in the Outflow tract on day 8.5[13] and BMP57 is highly expressed in the developing heart, as BMP6 is expressed in the myocardium and atrial-ventricular cushions of the outflow tract (OFT).[12] But it in AV (Atrioventricular) and OFT (Outflow tract) pads disappear on 9.5 and reduces on the right OFT on 10.5 and the 11.5.[12] BMP10 is expressed initially in all heart chambers of a rat. The role of BMPs as a signal involved in septation, as any defect in this process will be one of the most common causes of congenital heart disease. Therefore, signaling pathways of BMP in mesoderm formation and cardiac development is vital. BMP signaling regulates the induction of cardiac differentiation through a series of genes involved in the cardiogenesis by expression of NKX2.5 and GATA4 transcription factors.[14] That is why this study is designed to investigate the effect of STZ-induced gestational diabetes with expression changes of BMP5, BMP6, BMP7, and BMP10 in the heart tissue of E11.5 C57BL mice embryo.
Ethical approve
All animal experiments were approved by the Institutional Animal Care and Use Committee of the Golestan University of Medical Sciences, Gorgan, Iran (IR.gums.REC.1395.155)
Generation of gestational diabetes mellitus model
Twelve, 8-week old C57BL mice with an approximate weight of 130 g were housed separately with a male overnight for copulation. The next day vaginal plaque is checked, so it is seen considered as day 0 of pregnancy. Pregnant mice were allocated randomly into control and diabetic groups. Diabetes induced by a single intraperitoneal injection of a freshly prepared streptozotocin solution (150 mg/kg) in saline normal (0.85%) on day 1 of gestation.[15] Dams of the control group were injected with an equal volume of saline normal. 72 hours later, blood glucose levels were checked using a glucometer (ACCU CHEK, Roche Diagnostics, Germany). And the mice with a plasma glucose level higher than 200 mg/dl, was considered as the GDM model. Also, the blood glucose level of the control group was checked before and after pregnancy.[16]
Heart tissue collection
Control and diabetic mice were sacrificed by cervical dislocation on day 11.5 of gestation. Then, the embryos were removed by cesarean section. Heart tissues were extracted from embryos under a stereomicroscope and stored at −80°C until further use.
RNA cDNA synthesis
Total heart tissue from embryos of diabetic and control groups used for RNA extraction. Briefly, RNA was isolated from heart tissues using TRIZOL (Invitrogen) reagent according to the manufacturer's protocol. Residual DNA was digested with 10 U RNase-free DNase (TaKaRa) in the presence of 20 unit RNase inhibitor. After heat inactivation, the total RNA solution was removed and kept at −80°C. The concentration and purity of total RNA samples were measured using a Picodrop Spectrophotometer. The stability and integrity of the RNAs were estimated by agarose gel electrophoresis. For reverse transcription, 1 μg of total RNA was amplified using a cDNA synthesis kit (Fermentas).
Real-time reverse transcription-polymerase chain reaction assay
The forward and reverse polymerase chain reaction (PCR) primers for the 7 genes (S18, BMP 5, 6, 7, and 10) were designed using primer 3 software and were synthesized by Metabion (Martinsried, Germany). All the primer sequences are listed in [Table 1]. Real-time PCR was performed using the SYBR-Green PCR Master Mix kit (TaKaRa) in the Thermo Cycler (ABI, 7300). Mouse S18 used as a housekeeping gene and cDNA from the control group used as a calibrator. The relative gene expression level between the two groups was determined by the comparative cycle threshold (CT) method. The specificity of the amplified product was confirmed by gel electrophoresis. Every Real-time PCR experiment was repeated with four samples and each sample was run in duplicate.
Table 1: Real-time polymerase chain reaction primer name, sequences, size, and GenBank accession number
The value of 2-ΔΔCT was used to calculate relative changes in gene expression. Amplification plot comparison and CT comparison (CT, the first cycle with fluorescent intensity greater than baseline) are estimated for each gene. Finally, relative mRNA expression levels among diabetic and nondiabetic groups were determined by the CT method. Fold change gene expression was shown. Relative target gene expression (fold change) and blood glucose level data were analyzed by one-way ANOVA using Rest statistical analysis software. The differences between the two groups were compared using Student's t-tests and all P values were considered statistically significant If P < 0.05. Data were presented as a mean ± standard deviation.
Blood glucose level
Fasting blood glucose was measured in both control and diabetic group on day zero (G0) and day 3 (G3) of gestation. In diabetic pregnant mice, blood glucose level was significantly increased 72 h after STZ injection (P < 0. 05). The mean ± standard error of mean of blood glucose concentrations in control and diabetic mice is depicted in [Figure 1].
Figure 1: Serum glucose concentrations in diabetic and control pregnant mice on the zero-day of pregnancy (G0) and the third day of pregnancy (G3). Values are means ± standard error of mean. **P < 0.01
Quantitative Reverse Transcription-polymerase chain reaction results
In this study, we assessed whether the expression levels of bone morphogenetic genes including BMP5, BMP6, BMP7, and BMP10 were affected by gestational diabetes in the heart tissue of the embryo. Our data showed that the mRNA expression levels of all studied genes were higher in the heart tissue of embryos derived from GDM compared to controls. Data analysis showed that there was a significant increase in BMP6 in the heart tissue of the GDM-derived embryos in comparison with controls (**P ≤ 0.005). Although GDM-derived embryos showed increases in expression of BMP 5, 7, and 10, no significant differences were seen in compared to controls [Figure 2].
Figure 2: Real-time reverse transcription-polymerase chain reaction analysis of BMP-5, -6, -7, and-10 mRNA expression in the hearts of control and diabetic-derived embryo. Bar graph representing the fold changes of mRNA levels quantified by normalizing to the S18 as a housekeeping gene. Data are presented as mean ± standard deviation. BMP: Bone morphogenetic protein
Diabetes in pregnant women is associated with a fivefold increase in the risk of cardiovascular malformations in their offspring. The most common congenital heart defects are associated with cardiomyocyte hypertrophy, interventricular septum defects, common outflow tract, and heart valves malformations.[17],[18] In laboratory animals, it has been proven that the thickness of the ventricular septum and the weight of the heart in the Offspring of STZinduced diabetic rats is significantly higher than untreated Ones.[19],[20]BMP is involved in the regulation of many processes underlying cardiovascular development.[21],[22] Therefore, the researchers show that BMP signaling has an important role in heart morphogenesis after the midgestation stage.[3],[6]
This study was designed to determine the effect of induced GDM on BMPs expression in the heart tissue of E11.5 embryos in C57BL mice. In the present study, the expression of all studied genes in the E11.5 embryos of C57BL diabetic mice was higher than controls. We observed more than a 2-fold increase in BMP6 in the heart tissue of mouse embryos obtained from diabetic mothers (**P ≤ 0.005). Furthermore, we also showed that GDM upregulates expression of BMP10 and BMP5 in embryonic heart tissue by 1.76 and 1.58 fold, respectively.
Previous studies demonstrated that the BMP signaling pathway regulates the differentiation of cardiomyocytes from the mesoderm. Although, many studies have shown the role of BMPs in the formation of the ventricular chambers and septovalvulogenesis plus. On the other hand, both inhibition and stimulation of BMP are required for normal cardiomyocyte differentiation during heart development.[3],[22] So, these proteins can play a dual role in heart development.
In the developing heart under hyperglycemia, it seems that oxidative stress associated with malformations and subsequently formation of free radicals disrupt TGF-β and Wnt signaling.[23] Possible pathways concerning GDM induced congenital heart defects have occurred through BMPs shown in [Figure 3]. BMPs form a complex with type I and type II receptors, and the type I receptor causes phosphorylation of SMAD1, SMAD5, or SMAD8. Phosphorylated SMADs form a complex with SMAD4.[6] Which is transported into the nucleus and affects the genes GATA4, NKX2/5, and MEF2C, which play an important role in normal heart development.[24]
Figure 3: Possible pathway for gestational diabetes mellitus-induced congenital heart defects through bone morphogenetic proteins
Despite the importance of the BMPs in cardiac development and also the influence of GDM on the induction of heart malformations, no detailed study has been conducted on the effect of maternal diabetes on the expression of these genes in developing a heart. In conclusion, our data indicated that GDM can cause the upregulation of BMPs in the developing heart of E11.5 embryos in C57BL mice. Upregulated BMPs can affect important genes involved in cardiomyocyte hypertrophy. Taken together, these findings might be helpful in the understanding of the mechanism underlying GDM caused heart failure in the offspring. However, it seems that studying normal and abnormal cardiac development is necessary to fully appreciate the exact molecular mechanism of inducing cardiac defects in offspring by gestational diabetes.
The developmental period of the heart occurs on different days in uterus (7.5–15.5), but in this study due to the limitations, only on day 11.5 of gestation. Furthermore, no histological and morphological study was performed on the tissue surface, only at the level of gene expression has been examined.
This study was funded by Golestan University of Medical Sciences (grant number: 174411). Hence, we acknowledge the support of Golestan University of Medical Sciences for financial support of this research.
This study was financially supported by Deputy of research of Golestan University of Medical Sciences, Gorgan, Iran.
American Diabetes Association. 2. Classification and Diagnosis of Diabetes. Diabetes Care. 2015;38(Supplement 1):S8.
Dennery PA. Effects of oxidative stress on embryonic development. Birth defects research Part C, Embryo today : reviews. 2007;81:155-62.
Miyazono K, Kamiya Y, Morikawa M. Bone morphogenetic protein receptors and signal transduction. Journal of biochemistry. 2010;147:35-51.
Wang J, Greene SB, Martin JF. BMP signaling in congenital heart disease: New developments and future directions. Birth defects research Part A, Clinical and molecular teratology. 2011;91:441-8.
Bandyopadhyay A, Yadav PS, Prashar P. BMP signaling in development and diseases: A pharmacological perspective. Biochemical pharmacology. 2013;85:857-64.
Wang RN, Green J, Wang Z, Deng Y, Qiao M, Peabody M, et al. Bone Morphogenetic Protein (BMP) signaling in development and human diseases. Genes & diseases. 2014;1:87-105.
Van Gelder MM, Van Bennekom CM, Louik C, Werler MM, Roeleveld N, Mitchell AA. Maternal hypertensive disorders, antihypertensive medication use, and the risk of birth defects: a case-control study. BJOG: An international journal of obstetrics and gynaecology. 2015;122:1002-9.
Correa A, Gilboa SM, Besser LM, Botto LD, Moore CA, Hobbs CA, et al. Diabetes mellitus and birth defects. American journal of obstetrics and gynecology. 2008;199:237.e1-9.
Mitanchez D, Yzydorczyk C, Siddeek B, Boubred F, Benahmed M, Simeoni U. The offspring of the diabetic mother--short- and long-term implications. Best practice & research Clinical obstetrics & gynaecology. 2015;29:256-69.
Chu C, Gui YH, Ren YY, Shi LY. The impacts of maternal gestational diabetes mellitus (GDM) on fetal hearts. Biomedical and environmental sciences : BES. 2012;25:15-22.
Wang G, Huang WQ, Cui SD, Li S, Wang XY, Li Y, et al. Autophagy is involved in high glucose-induced heart tube malformation. Cell cycle (Georgetown, Tex). 2015;14:772-83.
Piotrowska I. Functional implications of Bone Morphogenetic Protein 10 (BMP10) expression in pathological hearts: Max Planck Institute for Heart and Lung Research, Bad Nauheim. Justus-Liebig university of Giessen; 2007.
Harmelink C, Jiao K. Bone Morphogenetic Protein Signaling Pathways in Heart Development and Disease. Congenital Heart Disease 2012.
Association AD. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2013;36(Supplement 1):S67-S74.
van Wijk B, Moorman AF, van den Hoff MJ. Role of bone morphogenetic proteins in cardiac differentiation. Cardiovascular research. 2007;74:244-55.
Damasceno DC, Sinzato YK, Bueno A, Netto AO, Dallaqua B, Gallego FQ, et al. Mild diabetes models and their maternal-fetal repercussions. Journal of diabetes research. 2013;2013:473575.
Lister R, Einstein F, Chamberlain A, Dar P, Bernstein P, Zhou B. Streptozotocin dosing for the induction of fetal cardiac dysmorphology associated with maternal hyperglycemia. American Journal of Obstetrics & Gynecology. 2012;206:S131.
Zielinsky P, Luchese S, Manica JL, Piccoli AL, Jr., Nicoloso LH, Leite MF, et al. Left atrial shortening fraction in fetuses with and without myocardial hypertrophy in diabetic pregnancies. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 2009;33:182-7.
Corrigan N, Brazil DP, McAuliffe F. Fetal cardiac effects of maternal hyperglycemia during pregnancy. Birth defects research Part A, Clinical and molecular teratology. 2009;85(6):523-30.
Menezes HS, Zettler CG, Calone A, Correa JB, Bartuscheck C, Costa CS, et al. Regression of gestational diabetes induced cardiomegaly in offspring of diabetic rat. Acta cirurgica brasileira. 2009;24:251-5.
Reinking BE, Wedemeyer EW, Weiss RM, Segar JL, Scholz TD. Cardiomyopathy in offspring of diabetic rats is associated with activation of the MAPK and apoptotic pathways. Cardiovascular Diabetology. 2009;8:43.
Yu W, Zha W, Guo S, Cheng H, Wu J, Liu C. Flos Puerariae extract prevents myocardial apoptosis via attenuation oxidative stress in streptozotocin-induced diabetic mice. PloS one. 2014;9:e98044.
Guo WT, Dong DL. Bone morphogenetic protein-4: a novel therapeutic target for pathological cardiac hypertrophy/heart failure. Heart failure reviews. 2014;19:781-8.
Caliceti C, Nigro P, Rizzo P, Ferrari R. ROS, Notch, and Wnt signaling pathways: crosstalk between three major regulators of cardiovascular biology. BioMed research international. 2014;2014:318714.

redpajama_set_name: RedPajamaCommonCrawl


The Buddha's eyes are downcast.
The Buddha sits on a black and red lacquered lotus throne in the virasana posture.
The Buddha is portrayed as walking, lifting the left foot slightly from the ground.
Skillfully carved in openwork relief from a single piece of wood, it remains in good condition.
Small bronze Buddha head with almond-shaped eyes that have heavy lids.
Circa 150-200 years old wooden seated Shan Buddha with Gems.
Small marble seated Buddha with gold leafing and benevolent facial expressions.
This Hanuman style khon mask was used during the classical dance- drama in Tailand for special occassions.
Japanese Buddha portable travel shrine with three folding panels.


Yes. There several ways to combine the Wanderfuls bouquets with fresh flowers. Best bet is to give us a call so we can share the flower secrets with you. Of course, there really is no need to use flowers with the Wanderfuls Bouquets because your guests will believe that they are flowers when they walk into the room.


The place where the present church is located has at least three churches erected. The first known church was probably built in the 1200s.
The church seems to have belonged to the kind of churches called "Kalmar Coastal Church" - a stone church without tower consisting of several floors and had the dual function of of worship and the defense establishment. There are also unique farm cemetery graves.
The church was visited July 12, 1795 by King Gustaf IV Adolf.


Nazca Lines Vandalism or Real Airplane Seen in Google Maps?
The Nazca Lines have been in existence for thousands of years and are proof that natives of the Nazca desert had the capability to make giant drawings that can only be appreciated from the air. The feat has led to speculation that these ancient people had the capacity to fly using hot air balloons and even gliders. Indeed, small gold figures of what appear to be aircraft had been found in the area. These have been concluded to be figures of birds, but some people see otherwise.
What came as a surprise to me when viewing them using Google Maps was a "recent drawing" of an airplane - which looked as if it was done in the same manner the ancients did - moving rocks to expose the lighter sand underneath. At a glance, it may look like the worst kind of environmental vandalism to be made on an ancient archaeological site apart from the swirling tire tracks already present near the highway.
If it's not for real (or a real plane carrying tourists), then it's likely a "photoshopped" practical joke made by someone who messed around with Google Maps. It can be pretty misleading. But it's likely a real plane flying over the lines! Anyway, there's the picture grab. You can look for it yourself in Google Maps.
Save gas! Convert your car to burn water.
Southwest of the plane you can see its shadow. Apparently the photograph was taken from an airplane that was flying a lot higher.
Yes, it's a real plane, likely carrying tourists. There are others to be found if you have the patience. They can take you by surprise if you see them for the first time on Google Earth.


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Focused on presidential bid, Ron Paul has missed 92 percent of votes in 2012
By Eryn Dion - 04/05/12 03:35 PM EDT
Rep. Ron Paul (R-Texas) has missed nearly 92 percent of House votes this year while campaigning for president.
Paul's bid for the White House has lost steam in recent weeks, but he has given little indication he will drop out of the race. The congressman has announced he will not seek a 10th term.
The libertarian lawmaker has called for slashing congressional pay and perks. If elected commander in chief, Paul — who now makes $174,000 a year — has pledged to take a salary of $39,336, "approximately equal to the median income of the American worker," according to his campaign website.
It is not uncommon for Republican and Democratic members running for the White House to miss congressional votes. For example, then-Sens. Hillary Clinton Hillary Diane Rodham ClintonThe Hill's Morning Report - Presented by Facebook - Democrats see victory in a voting rights defeat Left laughs off floated changes to 2024 ticket A year into his presidency, Biden is polling at an all-time low MORE (D-N.Y.) and Barack Obama Barack Hussein ObamaBarack Obama wishes a happy 58th birthday to 'best friend' Michelle Voting rights is a constitutional right: Failure is not an option Florida looms large in Republican 2024 primary MORE (D-Ill.) were rarely seen on Capitol Hill during their 2008 presidential primary clash.
The Hill reported last July that Rep. Michele Bachmann Michele Marie BachmannBoehner says he voted for Trump, didn't push back on election claims because he's retired Boehner: Trump 'stepped all over their loyalty' by lying to followers Boehner finally calls it as he sees it MORE (R-Minn.) had missed about 37 percent of votes in the House since launching her presidential bid. At that time, Paul had missed only 8 percent of the votes since announcing his White House run in mid-May.
Since then, his absenteeism rate has soared. In 2012, Paul has missed 136 votes while casting only 15.
According to GovTrack.us, Paul has missed 91.8 percent of roll call votes for the first quarter of 2012, the highest in his career. He went long stretches this year without setting foot on the House floor and then would show up to vote on a high-profile bill before jetting off again.
During the longest of these stretches, from Jan. 19 to Feb. 27, he was absent for 69 votes in a row. Paul last voted on March 29 on two amendments to Rep. Paul Ryan Paul Davis RyanOn The Trail: Retirements offer window into House Democratic mood Stopping the next insurrection Former Sen. Bob Dole dies at 98 MORE's (R-Wis.) budget. He missed the final vote on passage, however.
"In general, legislators try to keep their participation rates exceedingly high, since no one wants a challenger running an ad against him/her for missing votes," said Sarah Binder, professor of political science at George Washington University and a senior fellow at the Brookings Institution. "But Rep. Paul's running for president and he's giving up his House seat, so I doubt he's worried about being attacked for failing to show up for work in the House."
In 2008, Paul had to fend off a primary challenger who accused the lawmaker of not focusing on his Texas district.
Paul, 76, has attracted a large following and amassed large campaign war chests for his 2008 and 2012 White House bids. But he has failed to capture a state in his two most recent campaigns for the presidency.
Binder said, "I don't see the inconsistency between advocating limited government and failing to participate in every roll call vote. This is just a reality of our political system and the way that it fosters political ambition. It's common for politicians to run progressively for higher and higher offices, and it's tough to hold one office and run for another at the same time."
Paul has not been campaigning as much as he was earlier this year. On March 20, he appeared on "The Tonight Show With Jay Leno."
Paul's office did not comment for this article.
— Oliver Bussell contributed.
Tags Michele Bachmann Hillary Clinton Barack Obama Paul Ryan


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Fairbury McDonald's to close at end of August
FAIRBURY, NE — A fast food restaurant in Fairbury will be closing its doors next week. News Channel Nebraska has learned employees of the McDonald's in Fairbury have been notified the location's last day open will be August 30.
Wednesday, August 24th 2022, 7:16 PM CDT
Wednesday, August 24th 2022, 11:46 PM CDT
By Elic Chisam
FAIRBURY, NE — A fast food restaurant in Fairbury will be closing its doors next week.
News Channel Nebraska has learned employees of the McDonald's in Fairbury have been notified the location's last day open will be August 30. The closing of the location is reportedly due to the structure of the building, which is no longer considered "up to standards" of the restaurant chain, according to one employee.
According to the company's website, the minimum criteria for a location includes being on a lot of roughly 45,000 square feet with a building area of at least 4,500 square feet. The building also needs to be a minimum of 23' 4" and adhere to all local building codes.
Nebraska property records show the lot in Fairbury is 10,000-20,000 square feet. The building, constructed in 1982, is just over 2,000 square feet.
News Channel Nebraska reached out to McDonald's for a comment on the matter Wednesday afternoon and has not received a response at the time of publishing.
Once the location closes, Beatrice will house the only McDonald's location within 40 miles of Fairbury.


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WATCH for Scale: Cramer's 'Mad Money' Recap (Thursday 7/11/19)
Jim Cramer highlights companies that can grow so big they make their own destinies: Walmart, Amazon, Target, Costco and Home Depot.
If you want to be in the business of picking great stocks, look for companies that have scale, Jim Cramer told his Mad Money viewers Thursday. Scale has always mattered, Cramer said, but some companies have made leveraging their scale an art form.
Cramer unveiled a new acronym for his favorite retail stocks with scale. He called it "WATCH," which stands for Walmart (WMT - Get Report) , Amazon (AMZN - Get Report) , Target (TGT - Get Report) , Costco (COST) and Home Depot (HD - Get Report) .
Walmart was following in the footsteps of Sears not too long ago, but the company quickly invested in its online business, paid its employees more and now is a force to be reckoned with. Amazon is, of course, the king of scale, and not just in retail. Meanwhile, Target has also reinvented itself with a new smaller, urban format that shoppers love.
Costco has been a long-time Cramer favorite and he called the company magicians for how it's able to sell products for less than other companies buy them. Finally, there's Home Depot, the king of home and garden supplies. Cramer said Home Depot can make or break a brand thanks to its vast footprint and high product turnover.
Investors looking for a solid retailer to add to their portfolios can consider any of these great stocks, Cramer concluded, because they all have the scale to innovate and win.
Cramer and the AAP team are looking at everything from earnings and tariffs to the Federal Reserve. Find out what they're telling their investment club members and get in on the conversation with a free trial subscription to Action Alerts Plus.
Tracking FedEx
When a stock is able to rally on bad news, that's typically a sign that the bottom is near, Cramer reminded viewers, as he highlighted FedEx (FDX - Get Report) , which now trades at just 11 times earnings.
The transportation stocks are off 11% from their highs earlier this year as signs of a global trade-induced slowdown began to materialize. Shares of FedEx are off 29% over the past year. The stock had a brutal May, as trade talks broke down and tariffs escalated, but since then, things seem to have stabilized.
When FedEx reported two weeks ago, the company admitted that the global environment remains challenging and 2019 will be another year of change and transition for many companies around the globe. But since those remarks, shares have rallied from $156 to $162, Cramer noted, and that's a sign of strength.
Shares of FedEx have historically traded for 16.4 times earnings, Cramer said, which makes their current level of 11 times earnings even more attractive as all of the bad news is already baked into the stock, but none of the positives.
On Real Money, Cramer keys in on the companies and CEOs he knows best. Get more of his insights with a free trial subscription to Real Money.
Reviewing Cannabis Stocks
Just a few months ago, CEOs in the cannabis sector were making some pretty bold claims. But in the prevailing months, the pot stocks have cooled, forcing Cramer to reevaluate the entire group.
Last year, the cannabis stocks caught fire after Canada legalized recreational use. But this week we learned that the leader in the industry, Canopy Growth (CGC - Get Report) has seen pricing decline and production slow as costs began to skyrocket. These changes led to CEO Bruce Linton's firing at the hands of its biggest investor, Constellation Brands (STZ - Get Report) .
Here in the U.S., investors also overestimated the importance of cannabis-derived CBD products, which now face regulations by the FDA. It turns out food and spirits companies are reluctant to add CBD to their products in an uncertain regulatory environment.
What do all of these changes mean for investors? Cramer said he still sees Canopy as the leader in the sector. He also still recommended Cronos Group (CRON - Get Report) , which received an investment from Altria (MO - Get Report) , as well as GW Pharmaceuticals (GWPH) . Cramer said to avoid the rest of the cannabis stocks until we start seeing some hard facts, like same-store sales growth and earnings per share. He would even avoid cannabis ETFs, as they lump all of these bad names into one security.
Executive Decision: Tellurian
For his "Executive Decision" segment, Cramer again sat down with Charif Souki, co-founder and chairman of Tellurian (TELL - Get Report) , the liquified natural gas exporter that's building a new export terminal in Louisiana.
Souki explained that oil giant Total has agreed to a $900 million investment in Tellurian. Total will be investing $500 million directly into the Louisiana facility and have agreed to buy 1.5 million tons of gas, among other investments.
Souki said the Permian Basin in the U.S. have now become the swing oil producer in the world and what happens in the U.S. matters more than what happens with OPEC. The Permian is projected to increase oil output from 4 million to 8 million barrels a day. Souki said all of that natural gas can be on the water and ready to sell for a price so low it has no competition. "We just need to build the infrastructure," he added.
This increased oil production has created a crisis for natural gas, Souki continued. The U.S. is now the fourth largest country for burning, or flaring, our excess gas into the atmosphere and in another two years, we will be the largest. "This is simply not acceptable," Souki said. The U.S. must capture and do something with our natural gas.
In his "No-Huddle Offense" segment, Cramer said the clock is ticking at Bed Bath & Beyond (BBBY - Get Report) and time may be running out for new CEO Mary Winston.
On the company's conference call, Winston admitted that Bed Bath & Beyond must upgrade their stores to give customers a reason to shop there, but Cramer said he remains skeptical given the chain must compete with likes of Target and Amazon, both of which are also investing to woo customers.
Bed Bath still has $1 billion in cash, but Cramer said that may not be enough to upgrade over 1,000 locations. The company has already squandered millions repurchasing 40% of its shares, a move that did absolutely nothing for the share price.
With same-store sales declining rapidly, Cramer said there simply may not be enough time or money to turn this retailer around and give it a reason to exist.
Lightning Round
In the Lightning Round, Cramer was bullish on Sarepta Therapeutics (SRPT - Get Report) , Wingstop (WING - Get Report) , Visa (V - Get Report) and W. P. Carey (WPC - Get Report) .
Cramer was bearish on Amgen (AMGN - Get Report) .
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The Biggest Takeaway From Jerome Powell's Testimony
At the time of publication, Cramer's Action Alerts PLUS had a position in AMZN, HD, AMGN.


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Nanos nitens är en skalbaggsart som beskrevs av Lebis 1953. Nanos nitens ingår i släktet Nanos och familjen bladhorningar. Inga underarter finns listade i Catalogue of Life.

Källor

Bladhorningar
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Q: An error occurred while analyzing 'package-lock.json' (Node Audit Analyzer) I try to use dependency-check-maven in every test build job in Jenkins:
mvn org.owasp:dependency-check-maven:6.2.2:aggregate -DskipSystemScope=true -Dformat=ALL -DprettyPrint=true -DcentralAnalyzerEnabled=false -DassemblyAnalyzerEnabled=false -DyarnAuditAnalyzerEnabled=false -DbundleAuditAnalyzerEnabled=false -DversionCheckEnabled=true

Unfortunately I have a problem with few projects and Node Audit Analyzer, which checks package-lock.json files.
During running Maven's plugin there's a warning in log:
[WARNING] An error occurred while analyzing '/var/lib/jenkins/workspace/testbuild/project/module-web/src/main/resources/dev/package-lock.json' (Node Audit Analyzer).

which cause final error:
[ERROR] Failed to execute goal org.owasp:dependency-check-maven:6.2.2:aggregate (default-cli) on project project: One or more exceptions occurred during dependency-check analysis: One or more exceptions occurred during analysis:
[ERROR]     AnalysisException: Failed to read results from the NPM Audit API (NodeAuditAnalyzer); the analyzer is being disabled and may result in false negatives.
[ERROR]         caused by SocketException: Connection reset
[ERROR]     AnalysisException: Failed to read results from the NPM Audit API (NodeAuditAnalyzer); the analyzer is being disabled and may result in false negatives.
[ERROR]         caused by IOException: Error writing to server

In most problematic projects there's only one error: SocketException: Connection reset OR IOException: Error writing to server, but sometimes there are both of them in the same build log.
To use this plugin I added parameter -DnodeAuditAnalyzerEnabled=false but it's not a solution I want to accept.
I tried to execute Maven in debug mode. Here's a stacktrace with mentioned error:
[DEBUG] Error reading dependency or connecting to NPM Audit API
java.io.IOException: Error writing to server
    at sun.net.www.protocol.http.HttpURLConnection.writeRequests (HttpURLConnection.java:699)
    at sun.net.www.protocol.http.HttpURLConnection.writeRequests (HttpURLConnection.java:711)
    at sun.net.www.protocol.http.HttpURLConnection.getInputStream0 (HttpURLConnection.java:1585)
    at sun.net.www.protocol.http.HttpURLConnection.getInputStream (HttpURLConnection.java:1492)
    at java.net.HttpURLConnection.getResponseCode (HttpURLConnection.java:480)
    at sun.net.www.protocol.https.HttpsURLConnectionImpl.getResponseCode (HttpsURLConnectionImpl.java:347)
    at org.owasp.dependencycheck.data.nodeaudit.NodeAuditSearch.submitPackage (NodeAuditSearch.java:176)
    at org.owasp.dependencycheck.data.nodeaudit.NodeAuditSearch.submitPackage (NodeAuditSearch.java:133)
    at org.owasp.dependencycheck.analyzer.NodeAuditAnalyzer.analyzePackage (NodeAuditAnalyzer.java:188)
    at org.owasp.dependencycheck.analyzer.NodeAuditAnalyzer.analyzeDependency (NodeAuditAnalyzer.java:145)
    at org.owasp.dependencycheck.analyzer.AbstractAnalyzer.analyze (AbstractAnalyzer.java:131)
    at org.owasp.dependencycheck.AnalysisTask.call (AnalysisTask.java:88)
    at org.owasp.dependencycheck.AnalysisTask.call (AnalysisTask.java:37)
    at java.util.concurrent.FutureTask.run (FutureTask.java:266)
    at java.util.concurrent.ThreadPoolExecutor.runWorker (ThreadPoolExecutor.java:1149)
    at java.util.concurrent.ThreadPoolExecutor$Worker.run (ThreadPoolExecutor.java:624)
    at java.lang.Thread.run (Thread.java:748)
[WARNING] An error occurred while analyzing '/var/lib/jenkins/workspace/testbuild/project/module-web/src/main/resources/dev/package-lock.json' (Node Audit Analyzer).
[DEBUG]
org.owasp.dependencycheck.analyzer.exception.AnalysisException: Failed to read results from the NPM Audit API (NodeAuditAnalyzer); the analyzer is being disabled and may result in false negatives.
    at org.owasp.dependencycheck.analyzer.NodeAuditAnalyzer.analyzePackage (NodeAuditAnalyzer.java:197)
    at org.owasp.dependencycheck.analyzer.NodeAuditAnalyzer.analyzeDependency (NodeAuditAnalyzer.java:145)
    at org.owasp.dependencycheck.analyzer.AbstractAnalyzer.analyze (AbstractAnalyzer.java:131)
    at org.owasp.dependencycheck.AnalysisTask.call (AnalysisTask.java:88)
    at org.owasp.dependencycheck.AnalysisTask.call (AnalysisTask.java:37)
    at java.util.concurrent.FutureTask.run (FutureTask.java:266)
    at java.util.concurrent.ThreadPoolExecutor.runWorker (ThreadPoolExecutor.java:1149)
    at java.util.concurrent.ThreadPoolExecutor$Worker.run (ThreadPoolExecutor.java:624)
    at java.lang.Thread.run (Thread.java:748)
Caused by: java.io.IOException: Error writing to server
    at sun.net.www.protocol.http.HttpURLConnection.writeRequests (HttpURLConnection.java:699)
    at sun.net.www.protocol.http.HttpURLConnection.writeRequests (HttpURLConnection.java:711)
    at sun.net.www.protocol.http.HttpURLConnection.getInputStream0 (HttpURLConnection.java:1585)
    at sun.net.www.protocol.http.HttpURLConnection.getInputStream (HttpURLConnection.java:1492)
    at java.net.HttpURLConnection.getResponseCode (HttpURLConnection.java:480)
    at sun.net.www.protocol.https.HttpsURLConnectionImpl.getResponseCode (HttpsURLConnectionImpl.java:347)
    at org.owasp.dependencycheck.data.nodeaudit.NodeAuditSearch.submitPackage (NodeAuditSearch.java:176)
    at org.owasp.dependencycheck.data.nodeaudit.NodeAuditSearch.submitPackage (NodeAuditSearch.java:133)
    at org.owasp.dependencycheck.analyzer.NodeAuditAnalyzer.analyzePackage (NodeAuditAnalyzer.java:188)
    at org.owasp.dependencycheck.analyzer.NodeAuditAnalyzer.analyzeDependency (NodeAuditAnalyzer.java:145)
    at org.owasp.dependencycheck.analyzer.AbstractAnalyzer.analyze (AbstractAnalyzer.java:131)
    at org.owasp.dependencycheck.AnalysisTask.call (AnalysisTask.java:88)
    at org.owasp.dependencycheck.AnalysisTask.call (AnalysisTask.java:37)
    at java.util.concurrent.FutureTask.run (FutureTask.java:266)
    at java.util.concurrent.ThreadPoolExecutor.runWorker (ThreadPoolExecutor.java:1149)
    at java.util.concurrent.ThreadPoolExecutor$Worker.run (ThreadPoolExecutor.java:624)
    at java.lang.Thread.run (Thread.java:748)
[INFO] Finished Node Audit Analyzer (31 seconds)

In the same log in debug mode I found URL used by the anylyzer - https://registry.npmjs.org/-/npm/v1/security/audits Maybe this service has some limits?
I would be grateful for any help.

A: I was getting a similar error:
NodeAuditAnalyzer failed on ...\package-lock.json
An error occurred while analyzing '...\package-lock.json' (Node Audit Analyzer).
Deleting package-lock.json and the node_modules directory then running npm install to recreate fixed the issue.

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For over 50 years, the Center for Strategic and International Studies (CSIS) has developed practical solutions to the world's greatest challenges. As we celebrate this milestone, CSIS scholars continue to provide strategic insights and bipartisan policy solutions to help decision makers chart a course toward a better world.
CSIS is a bipartisan, nonprofit organization headquartered in Washington, D.C. The Center's 220 full-time staff and large network of affiliated scholars conduct research and analysis and develop policy initiatives that look to the future and anticipate change.
Since 1962, CSIS has been dedicated to finding ways to sustain American prominence and prosperity as a force for good in the world. After 50 years, CSIS has become one of the world's preeminent international policy institutions focused on defense and security; regional stability; and transnational challenges ranging from energy and climate to global development and economic integration.
Thomas J. Pritzker was named Chairman of the CSIS Board of Trustees in 2015. Mr. Pritzker succeeds Senator Sam Nunn, who chaired the CSIS Board of Trustees from 1999 to 2015. John J. Hamre became the Center's president and chief executive officer in April 2000. CSIS was founded by David M. Abshire and Admiral Arleigh Burke.
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In partnership with AJC Westchester/Fairfield and The Jewish Historical Society of Fairfield County.
On a summer day in 1945, an Orthodox man and his grown son return to a village in Hungary while the villagers prepare for the wedding of the town clerk's son. The townspeople – suspicious, remorseful, fearful, and cunning – expect the worst and behave accordingly. The town clerk fears the men may be heirs of the village's deported Jews and expects them to demand their illegally acquired property back. A superb ensemble cast and lustrous black and white cinematography contribute to an eloquent drama that paints a complex picture of a society trying to come to terms with the recent horrors they've experienced, perpetrated, or just tolerated for personal gain.
Followed by an AJC Westchester/Fairfield sponsored high level, post-screening discussion with Máté Vincze, Consul for Cultural Affairs at the Hungarian Consulate in New York.
Free of charge. Reservations are encouraged.


text:
Computing / Edge Computing
The Latest Chat App for iPhone Needs No Internet Connection
A startup's software will let iPhone apps connect phones without the Internet.
by Tom Simonite
Mobile app stores are stuffed with messaging apps from WhatsApp to Tango and their many imitators. But FireChat, released last week for the iPhone, stands out. It's the only one that can be used without cell-phone reception.
Just between us: Peer-to-peer schemes like FireChat's send information without involving distant servers or wireless carriers.
FireChat makes use of a feature Apple introduced in the latest version of its iOS mobile software, iOS7, called multipeer connectivity. This feature allows phones to connect to one another directly using Bluetooth or Wi-Fi as an alternative to the Internet. If you're using FireChat, its "nearby" chat room lets you exchange messages with other users within 100 feet without sending data via your cellular provider.
Micha Benoliel, CEO and cofounder of startup Open Garden, which made FireChat, says the app shows how smartphones can be set free from cellular networks. He hopes to enable many more Internet-optional apps with the upcoming release of software tools that will help developers build FireChat-style apps for iPhone, or for Android, Mac, and Windows devices. "This approach is very interesting for multiplayer gaming and all kinds of communication apps," says Benoliel.
Anthony DiPasquale, a developer with consultancy Thoughtbot, says FireChat is the only app he's aware of that's been built to make use of multipeer connectivity, perhaps because the feature remains unfamiliar to most Apple developers. "I hope more people start to use it soon," he says. "It's an awesome framework with a lot of potential. There is probably a great use for multipeer connectivity in every situation where there are people grouped together wanting to share some sort of information." DiPasquale has dabbled in using multipeer connectivity himself, creating an experimental app that streams music from one device to several others nearby.
The new feature of iOS7 currently only supports data moving directly from one device to another, and from one device to several others. However, Open Garden's forthcoming software will extend the feature so that data can hop between two iPhones out of range of one another via intermediary devices. That approach, known as mesh networking, is at the heart of several existing projects to create disaster-proof or community-controlled communications networks (see "Build Your Own Internet with Mobile Mesh Networking").
Apps built to exploit such device-to-device schemes can offer security and privacy benefits over those that rely on the Internet. For example, messages sent using FireChat to nearby devices don't pass through any systems operated by either Open Garden or a wireless carrier (although they are broadcast to all FireChat users nearby).
That means the content of a message and metadata could not be harvested from a central communications hub by an attacker or government agency. "This method of communication is immune to firewalls like the ones installed in China and North Korea," says Mattt Thompson, a software engineer who writes the iOS and Mac development blog NSHipster. Recent revelations about large-scale surveillance of online services and the constant litany of data breaches make this a good time for apps that don't rely on central servers, he says. "As users become more mindful of the security and privacy implications of technologies they rely on, moving in the direction of local, ad-hoc networking makes a lot of sense."
However, peer-to-peer and mesh networking apps also come with their own risks, since an eavesdropper could gain access to local traffic just by using a device within range.
Open Garden's main product is an app that allows Android devices to share their Internet connections (see "Could You Spare Some Internet Access?"). However, Benoliel says that won't be coming to the iPhone anytime soon because the feature that FireChat relies on cannot be used to share data connectivity.
Peer-to-peer mobile communications and mesh networks could prove especially important in countries with minimal communications infrastructure. "You can see Google spending billions on fiber and balloons, but this is not going to solve the problem of ubiquitous mobile connectivity," Benoliel says. He argues that the spread of cheap Android phones across the world will make mesh networking feasible. "We need to create small Internets that can function on their own and [then] connect them to the big Internet."
Tom Simonite


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Home/science/Alan Wake 2 will be in third person, voice actor and protagonist – Nerd4.life
Alan Wake 2 will be in third person, voice actor and protagonist – Nerd4.life
Phil Schwartz December 14, 2021
Sam Lake of Remedy Games confirmed via Twitter that Alan Wake 2 it will be third person game. Additionally, it was announced that longtime actor and voice actor Alan Wake will be returning for the sequel.
The information, as you can see below, was shared via Twitter. Sam Lake is referring to it elka fuzz The actor who put Alan Wake's face in the first game will return to play the character. In addition to, Matthew Buretta The voice actor who voiced the character will be returning to work on Alan Wake 2.
Sam Lake took advantage of his Twitter profile to confirm that Alan Wake 2 will be a third person game. The information wasn't explicitly shared by the last presentation at The Game Awards 2021 (here's the trailer with the release period). The only certainty was related to the fact that this new chapter would be a survival game, as opposed to the first which was a very classic action game: many survival games focus on first person nowadays, so perhaps that is the reason why Lake preferred it. . Determine the third person's choice.
We also remember that Alan Wake 2 will remain on radio silence until next summer, so from now on we will not have the opportunity to discover information about the game.
Phil Schwartz
"Food expert. Unapologetic bacon maven. Beer enthusiast. Pop cultureaholic. General travel scholar. Total internet buff."
See also "Challenger: The Final Flight" shines a light on the missing astronauts and their families
"Food expert. Unapologetic bacon maven. Beer enthusiast. Pop cultureaholic. General travel scholar. Total internet buff."
The 20th Anniversary console has a tribute to Duke – Nerd4.life
It will be exclusive for those under the age of 13
The steadfastness of fools | Times Nurse
Mars Valley is larger than the Grand Canyon, and it is the largest in the solar system: NASA
Moderator: The video shows the funniest opinions of the users


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Jasmine Guy: Is She Alive or Dead?
Riya Garg
Jasmine Guy is well-known for portraying Whitney Gilbert in the Cosby Show episode "A Different World." Now, there are rumours that the actress may have passed away.
According to numerous articles and posts, Jasmine Guy may no longer exist. Continue reading to know is she alive or not?
For more updates follow newslangmedia.
What happened to Jasmine Guy?
The NAACP Image Awards for Outstanding Lead Actress in a Comedy Series have been given to Jasmine Guy for the past four years in a row. Her most recent appearance was in the medical drama Grey's Anatomy, in which she portrayed a friend of Richard Webber's character.
The actress is most known for her roles as Roxy Harvey in Dead Like Me and Sheila Grams Bennet in The Vampire Diaries. Both of these characters were played by the actress. As of the year 2022, she has made a name for herself in the industry and has become a face that is well-known across the Hollywood community.
There are whispers circulating that Jasmine Guy may have passed away, as we have already mentioned. Due to the absence of any official reporting on the matter, we decided to conduct an exhaustive study into it.
After reviewing a number of allegations and assertions, we have arrived to the conclusion that the actress is in good health and is still alive. Therefore, there is no need to worry and take it easy; the actress will be OK.
The actress reportedly debuted in 1982 with seven non-speaking episodes of Debbie Allen's Fame.
The actress gained notoriety for playing Whitley Gilbert in A Different World. a sitcom drama called A Different World. Jasmine Guy featured in the 1987-1993 NBC spinoff of The Cosby Show. She took Lisa Bonet's place as the show's lead after she left the programme.
Skylan Brooks
Angourie Rice
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Former Member Of The Planning Commission Abhijit Sen Died


The latest Gallup poll has revealed that the country's feelings about marijuana are definitely changing. Support for the legalization of marijuana has risen from 60 percent of the country last year to 64 percent in this year's poll. Even the sentiment from Republicans is reflecting this national shift in attitude. The poll revealed that 51 percent of people who consider themselves Republican support the end of prohibition and the legalization of marijuana. The number has risen from last year when only 42 percent were in favor of legalization. This total is a vast change in opinion from 2011's poll that showed only 50 percent support for the legalization of the plant. Since then, there has been a steady increase in support as the states with legal marijuana show just how successful regulation can be.
64 percent of Americans now favor marijuana legalization per a recent Gallup poll.
8 states and the nation's capital, Washington D.C., have all ended prohibition and decided to regulate the plant in the same way that alcohol is regulated. In the states with an active legal industry, crime has been reduced, opioid use and overdoses are down, teen use has not been impacted in any way, jobs have been created and tax revenue has been generated to help schools and the community at large. The success of these initiatives has led to a trend towards ending prohibition in other states across the country. At least 18 other states are expected to present legislature in 2018's legislative sessions that would allow marijuana to be regulated like alcohol. Vermont was the first state to approve the legalization of marijuana through legislature this year. However, the bill was vetoed by the governor.
Republican support for marijuana legalization is at a record high.
Unfortunately, the Department of Justice, headed by long time, vocal prohibitionist Jeff Sessions is not supportive of this view. He urged District Attorneys to seek the highest possible penalties for drug related charges earlier this year, called marijuana only slightly less awful than heroin and is known for saying that "good people don't use marijuana." He sent a letter to Congress earlier this year asking them to remove financial restrictions so that he could crack down on medical marijuana as well as blocking the forward movement towards medical marijuana research. His general approach reflects a combination of the Reagan's failed "Just Say No" campaign to reduce drug use and reefer madness propaganda.
Nonetheless, the majority of the country is in favor of legalization and advocates continue their pursuit to end the prohibition of the plant and regulate it in the same way that alcohol is regulated.


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Ashoka Elected in 2021 | United States
Jill Habig
Link to https://www.ashoka.org/en-us/fellow/jill-habig copied.
Public Rights Project
Jill Habig is bringing justice to the law by closing the gap between the values expressed in our laws and the lived reality of our most underserved communities.
Because of the pandemic, Jill Habig was selected by Ashoka as a Special Relationship (Virtual) using an online process.
All people are entitled to many legal rights—like fair wages, safe housing, non-discrimination, clean water and air, and beyond. And yet, these legal rights rarely translate into tangible outcomes for people because they are rarely enforced—meaning if a corporation doesn't pay their employees properly, or a landlord doesn't keep up to date with building codes, or an employer decides not to hire a person because of their skin color, or a factory expels illegal emissions into the air, they are never held accountable for their actions. But why? Often, it's because those that have the power to hold them accountable—especially state, local, and tribal governments—lack the resources they need to make sure these human, civil, and environmental rights are being followed. In instances where laws are being enforced, enforcement is being carried out inequitably— for example, when small, immigrant-owned businesses are held accountable, but we ignore big corporations that can't be bothered to follow the law.
That's why Jill and her team at the Public Rights Project (PRP) are on a mission to close the gap between the laws on the books and how those laws are enforced with underserved communities in mind. PRP is creating new legal networks, continuing education, and best practices that motivate and specifically enable state, local, and tribal governments to proactively and equitably ensure that rights to economic justice, environmental justice, and racial and gender justice are enforced.
PRP was born of Jill's experience leading affirmative litigation in the San Francisco local government and with the Attorney General's Office in California. She saw the potential for affirmative litigation to become an impactful tool for ensuring civil rights across communities if other offices could be supported with a playbook, incentives to resource the work, and a network . So, she and her team set out to do just that: simultaneously piloting and refining this litigation approach in the Bay Area while documenting it and building the field of work across the United States. The central aim of the Public Rights Project (PRP) is expanding public-interest "affirmative litigation" across the United States, especially at the city level. This requires transforming civil rights enforcement into something that happens proactively in every community across the country, powered by governments who understand their power and know how to use it to improve the lives of underserved people and their communities. To this end, PRP is building a network of civil servants working out of city and district attorneys' offices, which have the legal authority to enforce civil rights but have historically lacked the knowledge, capacity, and public pressure to do so. PRP works with these offices to create an affirmative litigation "playbook" that equips them to serve their communities in new and more effective ways. In order to push government offices to incorporate this more proactive rights-enforcing approach, they work with advocates and activists to create demand for this specific change.
PRP's network enables states, cities, and smaller municipalities to pursue enforcement activities that have traditionally been pursued by the federal government or not at all, providing structures that protect communities regardless of federal priorities and activating a "standing army" with the power and resources to litigate cases that other advocates can't touch due to legal limitations, like arbitration clauses and resource constraints. The model also allows different cities and offices to learn from and support each other in pursuing legal action against common problems ranging from lead poisoning to COVID-related eviction moratoriums to protecting the Post Office or supporting workers in the gig economy.
Ultimately Jill and PRP are transforming our expectations of government and rebuilding trust in local institutions in particular by equipping them with tools to meaningfully address civil rights issues that would otherwise go ignored. Jill and her team envision and work to create a world where rampant unaddressed civil rights violations are no longer a fact of everyday life but are rather rebutted and guarded against by talented and skilled civil servants who leverage the law to protect the most underserved rather than preserve the (inequitable) status quo.
When it comes to economic, gender, racial, and environmental justice, there is a large gap between the promise of our laws and people's lived experiences. 54% of Americans are victims of illegal corporate abuse, including wage theft, predatory lending, unsafe housing, and corporate pollution. Extensive research has also documented the prevalence of discrimination in housing, employment, and policing.
Much of this gap stems from the fact that across the country, laws guaranteeing our rights in the workplace, the marketplace, and the community are largely not enforced and, when they are, are not enforced equitably. Harms caused by under-enforcement of legal rights include direct harm to families' and communities' wealth, health, and life opportunities, damage to the economy, persistent racial wealth gaps, and erosion of trust in the rule of law.
Governments at the federal, state, and local levels have the authority to address these wrongs, but this authority is vastly underutilized. At the state and local level, the offices with legal authority largely lack the knowledge, capacity, tools, and motivation to lead effective, equitable enforcement that close the gap. These smaller offices have traditionally relied on the federal government to do the bulk of enforcement, which waxes and wanes substantially based on the priorities of each presidential administration. States and cities frequently don't have the personnel with training or expertise on issues like wage theft or consumer fraud. They get stuck in the self-perpetuating inertia of not pursuing these kinds of cases because they've never done them before.
Additionally, when government offices engage in the enforcement of civil rights and economic justice issues, the most common approach to public enforcement is fundamentally flawed and furthers institutional racism. Typically, government law offices pursue legal cases based on receiving a complaint from a resident—a resident who has the trust, knowledge, and resources to avail themselves of a government law office—or based on hearing about an issue in the media. These modes of case generation are fundamentally reactive and beholden to "squeaky wheels," while offices remain inaccessible to the most underserved populations due to community mistrust of government institutions and lack of awareness surrounding individual rights. If no one knows a DA's office could stop their employer from stealing their wages, they're never going to complain about that problem to the DA, thus ensuring staff never have a complaint to trigger an investigation.
First, PRP releases numerous guides and playbooks as resources for local and state offices. Among their most recent are guides for fighting corporate abuse, helping local governments promote safe and just communities, and focusing on "the power and potential" of state AGs in the fight to end police brutality. These playbooks serve as accessible resources for local and state offices to develop an arsenal of knowledge that can help them shift the culture of their offices towards one that represents and defends timely civil rights issues and areas of public concern.
To build the interpersonal network of lawyers leading affirmative litigation, Public Rights Project has three fellowship programs, two for early-career professionals who want to join state, local, or tribal governments as affirmative litigation and civil rights enforcement specialists, and one for mid-career professionals who want to pivot to or enhance their skills in civil rights enforcement work. Jill's team provides training and technical support to those fellows to equip them with the tools and skills they need to proactively enforce civil rights laws. Currently, PRP has reached over 60 government offices in over 20 states across the country, including state-level offices, cities of all sizes, and tribal governments. They are planning to double this via high-touch expansion in the coming years, as well as developing a suite of lower-touch materials, digital legal trainings and continuing education to further expand their network.
PRP's fellows and the government offices in which they work are members of the only network of its kind, which connects government legal offices (like those of city attorneys, district attorneys, and attorneys general) across geographies, levels of government, and issue areas—to unite in focusing on civil rights enforcement. This allows offices to learn from each other, share techniques, avoid "reinventing the wheel," and powerfully support each other. PRP has already seen collaborative successes, such as when the Chicago District Attorney's office was able to file an amicus brief supporting Massachusetts' COVID-19-related eviction moratorium, or when thirty-two local, state, and tribal governments connected through Public Rights Project to work together to challenge changes to the post office that were brought about by the Trump administration. The network is also well-positioned to take on and support each other in legal challenges to the employment practices of nationwide "gig economy" companies like Handy and Instacart, where federal action will likely be constrained by a closely divided congress and right-leaning Supreme Court, and pressure from multiple state and local government enforcers will be needed to force the companies to change their business practices. Many civil rights issues, from lead paint to workers' rights, persist across municipal boundaries—and are being more effectively addressed using this networked strategy.
PRP's network is reaching more and more offices by connecting with community advocates and activists, working at local levels to inform and engage them on the question of what these law offices can do for their community so that they, in turn, exert pressure on their local officials to adopt proactive civil rights enforcement models. In many places, the attorneys heading these offices are elected, and a commitment to civil rights enforcement equity is a compelling part of a platform. Jill's team builds and maintains relationships between these local groups and their local CA's, DA's, and AG's offices so that community priorities and needs inform enforcement strategies. For example, Jill's team interviewed workers at Handy and Instacart to assemble detailed information on how those companies were violating their rights and ignoring their needs. This information was, in turn, converted into legal action. When "defunding the police" is on the table for debate, Public Rights Project represents a tangible way for local government offices to pivot their resources from criminal justice enforcement policies that drain and harm communities. Instead, these resources can go towards proactive, equitable civil rights enforcement that makes communities stronger and healthier by closing equity gaps and promoting rights.
Jill's mother was the first woman elected to the school board in their small Midwestern town, and Jill watched her persistence result in meaningful change for the district. In Jill's first year of law school, she helped found the San Francisco Affirmative Litigation Project, a fellowship that paired Yale law students with city attorneys in San Francisco to help scale up impact litigation. The program, founded in 2007, has been able to sustainably grow its impact using an innovative business model that helps state and local governments self-sustain high-quality enforcement teams by using revenue from successful cases to fund permanent staff. Through this work, she saw the difficulty other cities had in building similar programs from scratch because there was no plan or playbook.
In 2015, working as part of the California Department of Justice, Jill led the creation and launch of the Attorney General's Bureau of Children's Justice and oversaw its work defending children's rights in the child welfare, education, and juvenile justice systems. Jill and her team built this new unit to bring cases that had not been brought before on issues like racial bias in school policing. Each time they wanted to innovate, Jill felt as if they were "reinventing the wheel" as they created partnerships and marshalled resources to make change. Her "wish lists" and keen sense of what was needed to enable more cities and states to do this type of work were the seeds of the Public Rights Project.


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How can I run a google pixel without the physical screen?
Android Central Question
I'm attempting to run a google pixel 3 without the physical screen. The phone will be used in remote management, so I have a remote management utility installed on the device as well.
Everything works flawlessly when the screen is installed - all apps and configurations work as they are intended. However, once the screen is removed, the phone doesn't work. On a pixel 3a I was able to attach just a ribbon cable for the screen without the actual screen, and when I pulled it up in airdroid, it would only display a condensed screen about 1/3 the height. On the Pixel 3 it doesn't load up at all.
I've connected the phone to my computer with USB debugging enabled. Without the screen it shows up in the devices list. But with the screen it doesn't even show up in the devices list. The only way to make the phone operational is to remove the battery cable then restart the phone. About 30% of the time it displays a message upon boot "This device failed to boot, do you want to factory reset", with an option of "yes" and "reboot" (selectable through the volume and power buttons).
Also of interesting note, if I power on the phone without the digitizer connected, I can use AirDroid just fine, but it won't register my clicks on the remote view screen. Which leads to believe the phone is registering the hardware of the screen and digitizer upon boot.
If I disconnect the digitizer and LCD after the phone is booted up, I can attach them both and it'll work. It's just when they're disconnected from the phone during the initial boot phase.
I tested this with a Galaxy S8 previously, and that phone worked just fine without the screen attached, and ran fine that way.
Does anyone have any ideas on how to "register" the hardware correctly? I'm not certain that's what's happening, but it appears to be something with the hardware not registering correctly, or something like that. What's odd, is that it doesn't work even with the ribbon cables attached. It requires the full screen to be connected to the ribbon cables.
I've searched up and down google, but there doesn't appear to be much information available on this, as it appears to be a very specific problem which not many people encounter.
IMANUT46
Re: How can I run a google pixel without the physical screen?
Whew !!!!


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The L&L Blog / Scrivener
Write Now with Scrivener, Episode No. 4: Annik Lafarge, Author of Chasing Chopin
Kirk McElhearn / 25 AUG 2021
Annik Lafarge's latest book is Chasing Chopin: A Musical Journey Across Three Centuries, Four Countries, and a Half-Dozen Revolutions. "I honestly don't think I could have written this book without Scrivener."
After a career in publishing, from being a publicist to senior editor, Annik Lafarge is now a consultant and advisor to authors. Her latest book is Chasing Chopin: A Musical Journey Across Three Centuries, Four Countries, and a Half-Dozen Revolutions. Annik talks about how important it is for authors to help market their books.
"I honestly don't think I could have written this book without Scrivener."
Annik Lafarge
Chasing Chopin
David Bellos: The Novel of the Century, The Extraordinary Adventure of Les Misérables
Michael Gorra, Portrait of a Novel, Henry James and the Making of an American Masterpiece
Tony Horwitz, Confederates in the Attic, Dispatches From the Unfinished Civil War
Scott Huler, Defining the Wind, The Beaufort Scale and How a 19th-Century Admiral Turned Science Into Poetry
Catherine Raven, Fox & I
Maggie O'Farrell, Hamnet
Learn more about Scrivener, and check out the ebook Take Control of Scrivener.
If you like the podcast, please follow it in Apple Podcasts or your favorite podcast app. Leave a rating or review, and tell your friends. And check out past episodes of Write Now with Scrivener.
After a career in publishing, from being a publicist to senior editor, Annik Lafarge is now a consultant and advisor to authors. She published On the High Line: Exploring America's Most Original Urban Park in 2012, and her latest book is Chasing Chopin: A Musical Journey Across Three Centuries, Four Countries, and a Half-Dozen Revolutions.
Over 25 years in publishing, Annik has held many roles. For her, "what people in the publishing business do for writers is that they enable them: editors enable authors to find their voice and find the narrative thread and shape their books and marketing people do what they do."
As someone with a lot of experience in publishing, Annik knew how to help market her own books. One point she stresses is that "the author is absolutely essential to the process of figuring out how to sell and market her book. And so as an author, I knew that a lot of the burden was on me; that the publicist who works at Simon and Schuster, who published my book, is not an expert in romantic music, or Chopin, or any of these things, and was going to rely on me."
Annik used Scrivener, during the research and writing process, to store information that she knew would be useful for promotion for her book. "I think a lot of authors resent the fact that so much of the burden is on them, they've written the book, they've gone through this whole process, but you're the expert, you've got to do a lot of the heavy lifting."
Annik set up a folder in the Scrivener Sidebar to take notes while she was working on the book. "Every time I had an idea, or I came across a journalist who was writing about my subject, or there was a competition, I would just throw it into that folder in the Sidebar. And then when it came time to fill out my author questionnaire and give information to my publicist, all that stuff was right there, you know, and I had an email list."
As part of her proactive approach to marketing her book, Annik got in touch with me when she discovered the podcast, suggesting that she might be an interesting guest, because of the unique way she uses Scrivener. (Authors interested in being a guest on Write Now with Scrivener can drop me an email at podcast@scrivenerapp.com.)
Annik was drawn to Chopin because "I found that over a series of many years that Chopin, and in particular, what's known as the Funeral Sonata, the Opus 35, with the very famous funeral march, just kept popping up everywhere I went, including in surprising places, like in a jazz club in Chicago after I had visited a friend there who was dying."
Annik is an amateur pianist, and has long played Chopin's music, but there was more that led her to focus on him. And she set out to look at the history of this work; not so much the musicology of the sonata, but the cultural and historical context around it. "I found that it was a really interesting way to write about Chopin, to write about the fascinating period that he lived in in the 19th century. It was this just exuberant period of innovation and technology and music and publishing. He was a very independent person who I found to be very different from the kind of cliché of the tragic, romantic hero that we've all kind of come to know."
Annik used Scrivener to hold and manage her research for Chasing Chopin. "For me, Scrivener is really like a giant database. And the thing that I love best is that it's like a three-dimensional way to organize and view and engage with every aspect of content in a writing project." And this project was complex. Annik needed to store texts, photos, music files, and more, and her Scrivener project was over 2 gigabytes. "This book involves a lot of different threads. One of the things that I love about about Scrivener is that you can have a thumbnail of a photograph, for instance, in the right-hand sidebar, and you can have a series of links, you can throw an MP3 link in there too, and it'll play in whatever music program you use."
Scrivener is, for Annik Lafarge, an essential tool for her writing. "It's an incredibly powerful search engine, particularly if you have an enormously detailed database like I do. I'm using it in a very three-dimensional way, that I honestly don't think I could have written this book without Scrivener."
Kirk McElhearn is a writer, podcaster, and photographer. He is the author of Take Control of Scrivener, and host of the Write Now with Scrivener podcast.
Use Quick Reference Windows to View Multiple Parts of Scrivener Projects
Customize the Scrivener Editor 1 - Setting Up the Editor


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3 keys in the Utah Jazz's 110-91 win over the Golden State Warriors
By Deseret News Mar 25, 2018, 8:55pm MDT
Ryan McDonald
Share All sharing options for: 3 keys in the Utah Jazz's 110-91 win over the Golden State Warriors
Utah Jazz guard Donovan Mitchell (45) shoots between Golden State Warriors guard Nick Young, left, and forward Jordan Bell during the second half of an NBA basketball game in Oakland, Calif., Sunday, March 25, 2018. (AP Photo/Jeff Chiu)
Jeff Chiu, AP
OAKLAND, Calif. — Facing the Golden State Warriors without All-Stars Stephen Curry, Kevin Durant, Klay Thompson and Draymond Green, the Utah Jazz used a strong second-half surge to cruise to a 110-91 win Sunday night.
Turning point: Up by six at halftime, the Jazz broke things open in the third quarter thanks to a 15-0 run early in the frame. They led by 24 at the start of the fourth quarter and cruised from there.
The hero: Seven Jazz players finished in double figures, led by Donovan Mitchell's 21 points.
3 keys:
• Utah shot over 48 percent from the field while Golden State shot under 42 percent. The Jazz made 12 3-pointers compared to just six for the Warriors.
• The Jazz finished with more rebounds, assists, blocks, fast-break points and points in the paint.
• Without their "Big Four," the Warriors turned to a makeshift lineup that saw just Quinn Cook (17) and Andre Igoudala (12) finish in double figures.
Jazz almanac: 42-32, Won 1
Playoff picture: The Jazz are tied with the Minnesota Timberwolves for seventh in the Western Conference but hold the eighth seed due to tiebreakers.
Next 3:
Wednesday, March 28, vs. Boston (50-23), 7:30 p.m. MDT
Friday, March 30, vs. Memphis (19-54), 7 p.m. MDT
Sunday, April 1 at Minnesota (42-32), 5 p.m. MDT
Jazz notes: A Stockton in a Utah uniform happened — and he'll get more chances
Utah Jazz blow out the guys wearing the Warriors jerseys, 110-91
Next Up In Sports
Analysis: Jazz lose to Houston Rockets, the worst team in the Western Conference
Could BYU women's hoops go all the way?
How the Cougars plan to avoid an emotional letdown against San Diego
Utah has a new defensive tackles coach, and he is a Ute legend


XV International Conference on Civilising Processes: The Legacy of Norbert Elias.
Organising the conference took more than a year of hard work. The call for and some of us plan to meet in the next Conference that will be held in Brazil in 2016.
I want to thank sincerely all the academics and students who attended. The Conference was possible due to the work of Monica Guitian (head of the Centro de Estudios Interdisciplinarios en Teoria Social), who worked on the organisation of the event with the support or Elena Oros and Alejandra González Bazua and a group of enthusiastic students I also appreciate the co-operation of the Dean of the Political Sciences School of the UNAM, Fernando Castañeda, who gave his academic and generous financial support to the conference. Thanks also to the Norbert Elias Foundation for its interest in our work and for financially supporting Cas Wouters's air ticket,and to Ademir Gebara and the Latin American Civilisational Group for their confidence in the Mexican organising committee and the opportunity they gave us when they proposed UNAM Mexico as the venue.


DistrictBug offers details on school districts and ISDs. This record is for READING SCHOOL DISTRICT school district in READING, VT. ISD and school district data is deemed reliable, but not guaranteed. More info at SchoolBug.


Background: Cross-sectional studies suggest an association of 25-hydroxyvitamin D with exacerbations in patients with COPD, but longitudinal evidence from cohort studies is scarce. The aim of this study was to assess the association of serum 25-hydroxyvitamin D with exacerbations and mortality in primary care patients with COPD.
Methods: In the main analysis, we included 356 patients with COPD (GOLD [Global Initiative for Chronic Obstructive Lung Disease] stages II-IV, free from exacerbations for ≥ 4 weeks) from a prospective cohort study in Dutch and Swiss primary care settings. We used negative binomial and Cox regression to assess the association of 25-hydroxyvitamin D with (centrally adjudicated) exacerbations and mortality, respectively.
Results: Baseline mean ± SD serum 25-hydroxyvitamin D concentration was 15.5 ± 8.9 ng/dL, and 274 patients (77.0%) had 25-hydroxyvitamin D deficiency (< 20 ng/dL). Compared with patients with severe 25-hydroxyvitamin D deficiency (< 10 ng/dL, n = 106 [29.8%]), patients with moderately deficient (10-19.99 ng/dL, n = 168 [47.2%]) and insufficient (20-29.99 ng/dL, n = 58 [16.3%]) concentrations had the same risk for exacerbations (incidence rate ratio, 1.01 [95% CI, 0.77-1.57] vs 1.00 [95% CI, 0.62-1.61], respectively).
In patients with desirable concentrations (> 30 ng/dL, n = 24 [6.7%]), the risk was lower, although not significantly (incidence rate ratio, 0.72 [95% CI, 0.37-1.42]). In patients taking vitamin D supplements, using different cutoffs for 25-hydroxyvitamin D or competing risk models did not materially change the results. We did not find a statistically significant association of 25-hydroxyvitamin D concentration with mortality.
Conclusions: This longitudinal study in a real-world COPD population that carefully minimized misclassification of exacerbations and the influence of confounding did not show an association of 25-hydroxyvitamin D with exacerbations and mortality.
Trial registry: ClinicalTrials.gov; No.: NCT00706602; URL: www.clinicaltrials.gov.