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Search results for: the-search-for-certainty
The Search for Certainty A Philosophical Account of Foundations of Mathematics
Marcus Giaquinto — 2002-06-06 in
Author : Marcus Giaquinto
The nineteenth century saw a movement to make higher mathematics rigorous. This seemed to be on the brink of success when it was thrown into confusion by the discovery of the class paradoxes. That initiated a period of intense research into the foundations of mathematics, and with it the birth of mathematical logic and a new, sharper debate in the philosophy of mathematics. The Search for Certainty examines this foundational endeavour from the discovery of the paradoxes to the present. Focusing on Russell's logicist programme and Hilbert's finitist programme, Giaquinto investigates how successful they were and how successful they could be. These questions are set in the context of a clear, non-technical exposition and assessment of the most important discoveries in mathematical logic, above all G--ouml--;del's underivability theorems. More than six decades after those discoveries, Giaquinto asks what our present perspective should be on the question of certainty in mathematics. Taking recent developments into account, he gives reasons for a surprisingly positive response.
The Search for Certainty
W.W. Spradlin — 2012-12-06 in Medical
Author : W.W. Spradlin
Who are we? What are we? How do we fit into the world? Or into the universe? These and other questions pertaining to ourselves and our environ ment are as compelling to us today as they were to our primitive ancestors. Throughout our history we have developed paradigms of thought that have attempted to answer these questions, each conceptual framework being par ticularly relevant to its age. We are, in the twentieth century, witnessing a complete reorganization of our thinking. We are now, with the aid of tech nology, able to bring together both ancient and new patterns of thought and to observe the emergence of a kaleidoscopic world view that is uniting the once dissonant theories of philosophy, religion, and science. This book sketches an historical picture of three world views that have shaped our ideas about ourselves. These conceptual formats that have so influenced us are not mutually exclusive and are present in all of us simulta neously, although to varying degrees depending upon our individual biases.
Frank J. Swetz — 2012 in Mathematics
Author : Frank J. Swetz
Self-contained and authoritative, this history of mathematics is suited to those with no math background. Its absorbing, entertaining essays focus on the era from 1800 to 2000. Contributors include Henri Poincaré, Judith V. Grabiner, and H. S. M. Coxeter, who discuss topics ranging from logic and infinity to Fermat's Last Theorem.
Krzysztof Burdzy — 2009 in Mathematics
Author : Krzysztof Burdzy
This volume represents a radical departure from the current philosophical duopoly in the area of foundations of probability, that is, the frequency and subjective theories. One of the main new ideas is a set of scientific laws of probability. The new laws are simple, intuitive and, last but not least, they agree well with the contents of current textbooks on probability. Another major new claim is that the OC frequency statisticsOCO has nothing in common with the OC frequency philosophy of probability, OCO contrary to popular belief. Similarly, contrary to the general perception, the OC Bayesian statisticsOCO shares nothing in common with the OC subjective philosophy of probability.OCO The book is non-partisan on the scientific side OCo it is supportive of both frequency statistics and Bayesian statistics. On the other hand, it contains well-documented and thoroughly-explained criticisms of the frequency and subjective philosophies of probability. Short reviews of other philosophical theories of probability and basic mathematical methods of probability and statistics are incorporated. The book includes substantial chapters on decision theory and teaching probability, and it is easily accessible to the general audience
— 1928 in Certainty
Search for Certainty
Mark Finley — 2010 in Bible
Author : Mark Finley
W. W. Spradlin — 1984-03-12 in
Author : W. W. Spradlin
The Search for Certainty in an Uncertain World
Federal Reserve Bank — 1962 in
Author : Federal Reserve Bank
It is Written (Television program) — 2000-03 in Bible
Author : It is Written (Television program)
This volume represents a radical departure from the current philosophical duopoly in the area of foundations of probability, that is, the frequency and subjective theories. One of the main new ideas is a set of scientific laws of probability. The new laws are simple, intuitive and, last but not least, they agree well with the contents of current textbooks on probability. Another major new claim is that the ?frequency statistics? has nothing in common with the ?frequency philosophy of probability,? contrary to popular belief. Similarly, contrary to the general perception, the ?Bayesian statistics? shares nothing in common with the ?subjective philosophy of probability.? This volume is non-partisan on the scientific side ? that it is supportive of both frequency statistics and Bayesian statistics. On the other hand, it contains well-documented and thoroughly-explained criticisms of the frequency and subjective philosophies of probability. Short reviews of other philosophical theories of probability and basic mathematical methods of probability and statistics are incorporated. This volume includes essential chapters on decision theory and teaching probability, and it is easily accessible to the general audience.
'Go Out and Study the Land' (Judges 18:2)
Marjolein Bastin 2017 Monthly/Weekly Planner Calendar: Nature's Inspiration
Counselling People with Communication Problems
Brotherhood Of The Rosicrucians Or Rosy Cross
Information Visualization, Third Edition: Perception for Design (Interactive Technologies)
Spectral Properties of Hamiltonian Operators
Personal Finance in Your 20s & 30s For Dummies
The Tact of Teaching: The Meaning of Pedagogical Thoughtfulness
Starship: First Steps to Empire
Show Me the Bunny! (SpongeBob SquarePants)
Vulcan Boys
Rainy Day Ramen and the Cosmic Pachinko
The Day the Black Rain Fell
Measuring the Flow of Time
Global Restructuring and Territorial Development
The International Handbook of Public Financial Management
Reader-Response Criticism
Dad, Am I Going To Die?
Fire Ecology in Rocky Mountain Landscapes
The Iron Ring
Hosting the Olympic Games
Top Secret: The Truth Behind Today's Pop Mysticisms
Sport and the Brain: The Science of Preparing, Enduring and Winning, Part B: Volume 234
Supporting the Highly Sensitive Child
The Conscript: A Novel of Libya's Anticolonial War (Modern African Writing Series)
The Public Years of Sarah and Angelina Grimke
Talking Leaf
Cat & Mouse
Between Jerusalem and Europe
Compact Key for Schools Student's Book without Answers with CD-ROM
The Greatest Gardening Tips in the World
Chatterbox: Level 4: Activity Book
Aquaman Volume 2: Amnesty
Figure Fantasy
French Inside Out
David's Tabernacle
Serene Flowers
I Am Here Now
The Body in Pain in Irish Literature and Culture
Adult Coloring Book Shine
A Little History of Religion
Arpeggio of Blue Steel Vol. 16
The Evolution of Mammalian Characters
Ultraman, Vol. 4
Part 2: Non-ferrous Alloys – Light Metals
Self-Help for Women
The Mental and Moral Philosophy of Laughter
Switzerland Then and Now
Using Your HP 95LX


This drawing is an exceptional drawing because we are going in an aerial view round Curacao but also this is the first full color, pencil and ink drawing that will be 3 meters and 60 centimeters long and 30 centimeters high.
On this page I will place the complete development of this 3 meters and 60 centimeters long and 30 centimeters drawing that I will make on 6 pieces of paper.
I call this drawing "Curacao 360" and it will be an extreme one.


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The easy way to hire 70's Bands, Funk Bands & Disco Bands in Merseyside
70's Bands, Funk Bands & Disco Bands for hire in Merseyside
59 of the finest Merseyside 70's Funk & Disco Bands to hire for your events
59 of the finest Merseyside 70's Funk & Disco Bands to hire for your events.
These are the perfect 70's Bands, Funk Bands & Disco Bands for weddings, corporate events & parties in Merseyside, locally sourced by our entertainment experts. Find the best Merseyside 70's Bands, Funk Bands & Disco Bands only at Alive Network, the UK's biggest entertainment agency.... More
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5 stars - La Frontera are Highly Recommended 15 Reviews
Number of members: 5 Merseyside
Performing an upbeat mix of Pop, Soul & Funky Dance, La Frontera are a versatile female fronted 5 piece. Providing unforgettable entertainment, this professional band cover material from Jessie J, Aretha Franklin, Stevie Wonder, Estelle & more!...
Fee for Merseyside
5 stars - Gold are Highly Recommended 65 Reviews
Number of members: 6 South Yorkshire
Gold are a premium quality function band available with 6, 7, 8 or 9 members. This international party band is made up of the highest quality professional musicians, who specialise in performing choice party tracks from a wide range of genres including Funk, Soul, Motown, Rock, Indie, Pop and Disco....
Soul Explosion
Performing the biggest Soul, Funk & Pop hits from the last 5 decades, Soul Explosion come armed with great grooves, killer vocals and a repertoire to keep your dancefloor full all night. Previous performance credits include Glastonbury, major Cruise Ships, Liverpool Philharmonic Hall, Edinburgh Fringe Festival & more....
The Divine Soul Collective
5 stars - The Divine Soul Collective are Highly Recommended 20 Reviews
Number of members: 6 Greater Manchester
Playing an accessible and lively soul based set, their playlist spans from the early 60's Motown sounds, the 70's funk and disco era, right up to the contemporary Soul hits of the modern era. Artists such as:- Stevie Wonder, Michael Jackson, Sister Sledge, Earth Wind & Fire, Jocelyn Brown, Beyoncé, Mary J Blige, Bruno Mars and many more. Guaranteed to get every generation up onto the dance floor... And keep them there!...
Andy Joseph
5 stars - Andy Joseph are Highly Recommended 57 Reviews
Andy Joseph is a modern day solo swing and soul singer, covering rat pack and crooner classics, through to soul and contemporary pop. Sir Alex Ferguson was recently captivated by Andy's style, vocal ability and personality. Also available as a duo with a live pianist or a full 9 piece live band....
5 stars - Asteroids are Highly Recommended 2 Reviews
A top quality function band who cover a range of genres and play them in their unique way. Upbeat, funky and guaranteed to make you dance - these guys know how to have fun on stage! You won't be dissapointed!...
Need help finding the perfect 70's Band for your event?
If you would like help selecting the perfect 70's funk or disco band for your event, simply give us a call or make a quick enquiry and one of our talented entertainment coordinators will be happy to assist.
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5 stars - Soul Stew are Highly Recommended 4 Reviews
Number of members: 7 North Yorkshire
Soul Stew's repertoire utilises the raw funk of King Curtis, the heavy bass of James Brown and the household hooks of Stevie Wonder plus many more! A dedicated band who love what they do, Soul Stew's passion for performing shines through at every event and is guaranteed to make your night!...
5 stars - BackBeat are Highly Recommended 63 Reviews
An electric group of 5 young, cool, professional musicians. Their ever expanding repertoire covers a huge range. From Soul, Funk, Motown & Disco to Rock & Pop, all your favorite party classics & latest modern day hits guarantee to get the party started!...
5 stars - Diva Divine are Highly Recommended 66 Reviews
Number of members: 1 Staffordshire
Diva Divine tributes a wide range of songs from the 60's to present day. With impeccable vocals, stunning costumes & plenty of audience participation!  Her huge repertoire includes the best Soul, Motown, Disco, Rock & Roll and Jazz Hits that were made famous by artists like Aretha Franklin, Whitney Houston, The Supremes, Stevie Wonder, Candi Staton, Rihanna, The Beatles, Madonna, The Jackson 5, Alicia Keys & many more!...
Soul Satisfaction
5 stars - Soul Satisfaction are Highly Recommended 4 Reviews
Graduates of Leeds College Of Music, Soul Satisfaction are a professional 6 piece band specialising in Funk, Soul, Motown & Pop! With a pure soulful sound and a stunning female vocalist Soul Satisfaction guarantee to provide you with top class music....
5 stars - The Family are Highly Recommended 25 Reviews
The Family are a Funk, Soul & Pop party band, performing a superb mix of classic and contemporary dance floor fillers. One of Manchester's finest function bands, the band work closely with you to ensure that the music for your event is perfect!...
5 stars - Soul Power are Highly Recommended 6 Reviews
Soul power are a professional high energy 9 piece funk and soul band from North Yorkshire. With over a decade of experience performing at venues such as Blenheim Palace, this band will be sure to leave you and your guests with a night to remember....
City Funk
5 stars - City Funk are Highly Recommended 5 Reviews
Number of members: 5 West Midlands
Superb energetic 5 piece band with accomplished soulful vocals, playing an awesome unique blend of modern & classic Funk, Soul, Motown, Disco & Rock 'n Roll!...
Sophie and the Exciters
5 stars - Sophie and the Exciters are Highly Recommended 25 Reviews
Number of members: 5 Northamptonshire
Fronted by Sophie, the first artist to perform at London's O2 Arena, Sophie & the Exciters are first class musicians with one of the largest set lists of music for a party band, from present day pop rock and indie, through to Soul, funk and Motown...
The Party Crashers
5 stars - The Party Crashers are Highly Recommended 35 Reviews
Combine the finest musicians from the Midlands, add an irresistibly varied repertoire of modern & classic party hits, then serve with a confident hard hitting performance to create the ultimate in live music. The Party Crashers are just that and more!...
Diva Soul Band
Diva Soul Band are a supergroup of first class musicians guaranteed to make your event! With their unique & authentic repertoire of classics from the 60s, 70s, 80s all the way up to present day, expect to hear songs from Aretha Franklin, Gladys Knight, The Supremes & The Vandellas, Tina Turner, even Beyonce and Bruno Mars!...
After 8s
5 stars - After 8s are Highly Recommended 21 Reviews
Superb energetic 8 piece band with male & female lead vocals, backing vocals & brass section! After 8's playing an awesome unique blend of modern & classic Funk, Soul, Motown, Disco, Rock 'n Roll, R 'n' B and House anthems!...
Groove Station
5 stars - Groove Station are Highly Recommended 15 Reviews
Number of members: 4 Edinburgh
The act to book if you really want to impress! With talented musicians & 1st class vocals, Groove Station offer a fantastic selection of foot stomping classics & contemporary cover tunes guaranteed to have your guests dancing all night long!...
The Nineties Brit Pop Collection
The 80s Collection
70's, Funk & Disco Band Hire Prices
5 Great Reasons To Book A 70's Disco Wedding Band
Vintage Wedding Entertainment
Top 14 Vintage Themed Corporate Entertainers
Wedding Entertainment Prices: What Can You Get For...
50 Corporate Entertainment Ideas for 6 Types of Ev...
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Everything you need to know to hire 70's Bands, Funk Bands & Disco Bands for your event
How much do Merseyside 70's Funk & Disco Bands cost?
70's Funk & Disco Bands in Merseyside cost from £402 to £7841. The average price in 2020 was £2150. Prices vary depending on experience, demand, size of act, travel costs and the specs of the equipment provided. Artists travelling into Merseyside from further away will usually charge more than a local act due to travel time and fuel costs.
We will always do our best to help you find 70's Funk & Disco Bands on your budget, so please give us a call if you can't find what you're looking for.
Do you have a 70's Funk or Disco Band near me?
Alive Network represents 70's Funk & Disco Bands throughout Merseyside, with acts available for events in Bebington, Billinge, Birkenhead, Bootle, Crosby, Formby, Haydock, Heswall, Hoylake, Huyton-With-Roby, Kirkby, Litherland, Liverpool, Maghull, Newton-Le-Willows, Prescot, Rainford, Southport, St Helens, Wallasey.
To see the most local Merseyside 70's Funk & Disco Bands, enter a search using your event date and location, then use the 'nearest me' sort option.
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Aside from finding some of the best 70's Funk & Disco Bands in the UK and getting expert advice from our friendly staff, one of the main reasons to hire a 70's Funk or Disco Band from Alive Network Entertainment Agency is security. We ensure your booking is covered 24/7 against any eventuality, so that no matter what, you can enjoy your event without worrying about whether your entertainment will turn up. If your 70's Funk or Disco Band is ill or unable to perform, our team will be on hand to source a suitable replacement even out of office hours and at short notice. Imagine having to do that yourself!?
Hand-picked 70's Funk & Disco Bands for the ultimate in quality and reliability
Hundreds of 70's Bands, Funk Bands & Disco Bands to choose from
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How do you join a 70's Funk or Disco Band agency?
There is no cost to join Alive Network but we are not a directory, so every application is individually assessed and we hand-pick the 70's Funk & Disco Bands we want to represent.
We look to recruit 70's Funk & Disco Bands who we feel are the best in their area, but who also represent good value for money.
The Leading 70's Bands, Funk Bands & Disco Bands Agency in Merseyside
Looking for 70's Funk & Disco Bands in Merseyside? Alive Network will help you hire the best local Merseyside 70's Funk or Disco Band, with acts available in Bebington, Billinge, Birkenhead, Bootle, Crosby, Formby, Haydock, Heswall, Hoylake, Huyton-With-Roby, Kirkby, Litherland, Liverpool, Maghull, Newton-Le-Willows, Prescot, Rainford, Southport, St Helens, Wallasey
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redpajama_set_name: RedPajamaCommonCrawl


194. To serve on a California jury, you must be a U.S. citizen. You must be selected to serve; juror names are selected from state identification cards, driver's licenses, and voting rolls. If selected, you will receive in your mail an envelope marked Jury Summons. Call the 800 phone number to find out the first day of your service. If that date is inconvenient for you, you can change it to a later date. You cannot serve more than once every 12 months.
If you are mentally disabled or are a full‐time caregiver, you may be excused from service. If you have no reasonable means of transportation to court, you might be excused. If you are a full‐time student or teacher, you won't be excused. If you are a breast‐feeding mom, you can postpone your service. If you are dead, your family must provide proof of death.
To serve on a jury, you must be able to read and understand basic English. Your age doesn't matter, as long as you are at least 18 years old. Once you're 70, you can say that you're too sick to serve; you don't need a doctor's excuse. If you're younger than 70, you need a doctor's note confirming that you are ill. Blind people, deaf people, and people in wheelchairs can be required to serve on a jury.
You will not get paid very much for your service—$15 a day. Also, the state will reimburse you 34 cents for each mile that you drive in your car (one way only). Some employers will pay your salary while you serve; some won't. If you own a business, you might be away from it for one to four weeks, occasionally even longer. You could lose a lot of money if you do most of the work for your business. But the judge won't excuse you unless you can demonstrate extreme financial hardship. Parking for jurors is always free.


Shark Attack Golf and American Power Golf has announced an APG Developmental Long Drive Event. There will be a fundraiser golf tournament and fundraiser on March 22, 2013 and a Amateur Long Drive event on March 23, 2013. These events will take place at Carolina Springs Golf Club in Fountain Inn, South Carolina. You may contact Moby / Matt Ellenburg at sharkattackgolf@gmail.com for more information or to register. Entry fee will be $150 for the Long Drive Event and $50 per player for the 4 man golf tournament the day before. There will be an on course long drive competition for a small fee with the 3 top players having a playoff for free entry into the APG event.
Get your name in to reserve a spot. We will begin collecting entry fees April 18-22 watch for PayPal address to be posted soon.
You know I'll be there!!
Will the winner of this event get a free buy in into the east coast classic? Or is this event simply developmental and you get nothing for it?
As it stands now, it's just a cash payout. The 2 events aren't really connected as the Skirmish is an amateur event and the East Coast Classic is an open Pro Event. All the payouts and places paid will be based on the turnout.
With that kind of price you can count me in.
Alright Boss...you're in. I'll update the list.
so how are you paying cash if its an amatuer?
Donnie, its a developmental event. Just like Metter, only cash instead of a paid spot. amatuer is listed bc its not going to include anyone in the top 150-200 it so. There is not a bigger event the day following this one. It's a stand alone APGDT event where you have a chance to win money.
Perhaps the correct term would be Developmental Event. This is a part of the American Power Golf Developmental Tour. We simply mean it's not an event for the accomplished Long Driver who is ranked high in the unofficial rankings. The goal of the developmental tour is basically a farm system to allow Long Drivers to get experience and hopefully move on to the bigger events and to compete for the big purses. It's a scale system...instead of having to pay $600 entry fees and competing for $8,000-$10,000, they put up $150-$200 and compete for a pot based on the money paid in...example $1,000 first place, etc. Hope that helps.
got ya. amatuer event threw me off as ams cant win cash. developmental sounds better. thanks for clarification.
cant wait cold weather is killing me i wanna hit balls lol.
Please add my name to the list of hitters.
Whoever came up with this developmental tour idea is a genius!
My hope is to be there!
I'll add you to this list Matthew. Thanks for being a part.
Hey Koolaid.....oh yeah!.....you need to come run wild on the grid.
Give some credit to the guy who came up with the Developmental name!!
Also wanted to update that there will be 3 EXECUTION SHAFTS offered as prizes during the Long Drive Event so play hard. Thanks to Mike Roach for the donation.
I'm trying to bring 3 other guys down to play Friday in the tourny, but if not... I definitely want to play in it!!!
Can the LD guys join forces and make a team or are you trying to put and LD'er on each team?


Hi Binx, welcome to VENTS! How have you been?
Howzit Vents! Thank you so much for interviewing me, I appreciate the support 🙂 I have been so excited. Non-stop writing and releasing and creating, it's keeping my spirits high and motivated for sure.
Absolutely. The song is a metaphor for keeping something in your focus. When you start to feel derailed from whatever it is you set out for in the first place, remember why it is that you started and keep going.
Yes. The song is about my Dad. He passed away last year. I was in a very dark place and I wanted to give up a career in music because it was bringing me more pain than pleasure. My dad was exceptionally involved in my life and career and he is the reason I became a musician. So I use the song as a reminder to keep my Dad in my thoughts as I continue my journey as a musician.
It was SO much fun. I could do it all day every day. We shot the video in my friends mansion and at the beach in Conneticut. We chose a day when the temperatures ended up being below freezing and I had a scene coming out of the ocean water. I'm surprised I never ended up getting frost bite or pneumonia! I had to constantly be covered with a blanket and stuff hand warmers into my wet holographic shoes.
It was an 18 hour shoot, we stayed until the sun had risen the next morning and I never slept and hardly ate anything because I was so busy.
Despite all of this, my energy levels were at an all time high and all of my best friends came out to help on set and make me laugh, so I got to hangout and be creative all at once, which is my absolute happy place. I am lucky to have them in my life.
The songs off of my "The African Bee" EP vary because "Radiohead" I wrote when I was 16 and most of the other tracks I had written recently or in my early 20's. So it's quite a wide range and my writing style has evolved. Recording is also exciting because I get to take a simple melody in my head, mix it with all the sounds I hear and turn it into a masterpiece.
What was it like to work with Kinetics and how did that relationship develop?
I felt honoured to work with him since he came recommended so highly, he's a great writer and also has a couple of hit songs under his name! (Haylee Williams and BOB – Airplanes, to name one.) He is also just a really lovely person and it was the first time I really co-wrote with someone else, I usually write everything myself. Jason Flom from Lava/Republic Records set up the co-write for us.
"Headlights" is the only song we wrote together, but the song is my most special one because of my Dad, therefore it's a massive influence to me.
What role does South Africa plays in your music?
South Africa will always play a massive role in my music. Growing up there with my mom, dad and brother was unique and blissful and the culture is unlike anything else. I will always try to incorporate my African roots as much as possible to share it with people who aren't as familiar with my country. Because I am extremely proud of where I come from. I even have a song called "African Heart" off of the EP and I sing in three different languages; English, Afrikaans and Xhosa.
I have also always received a tremendous amount of support from the people, press and radio.
So "Headlights" is actually part of my EP called, "The African Bee." But I have a new single coming in June and a new album will be coming this September 13 2017! I can't wait. It will be released once again on my Dad's birthday and the same day as "The African Bee" which was released last year.
The "Headlights" music video will be released 31st May, Wednesday 2017.
I will be releasing my next summer single "Paradise" in June, which I recorded at The Spotify Studios.
Yes, I am currently planning a trip to Los Angeles in July and South Africa in December to play a couple of shows and do a press tour with all the new releases I have coming up.
What else is happening next in BINXs world?
You can connect with me on social media and anyone who signs up to my mailing list will always receive the Buzz first!
You can sign up to my mailing list on my website because I always send new releases or new information to people on the list first.


1- Central Laboratory for Stem Cell Research and Translational Medicine, Centre for Liver Research and Diagnostics, Deccan College of Medical Sciences, Hyderabad, India.
2- Department of Genetics, Faculty of Science, Osmania University, Hyderabad, India.
3- Centre for Cellular and Molecular Biology, Hyderabad, India.
Introduction: The present study aimed to explore protective mechanisms of hypothermia against mild cold and heat stress on highly proliferative homogeneous human Neural Precursor Cells (NPCs) derived from Subventricular Zone (SVZ) of human fetal brain.
Methods: CD133+ve enriched undifferentiated and differentiated human NPCs were exposed to heat stress at 42°C. Then, Western-blot quantification was performed using Hsp-70 (70 kilodalton heat shock proteins) recombinant protein. Finally, changes in pluripotency and Hsp-70 expression were measured using immunofluorescence staining and RT-qPCR (Quantitative reverse transcription PCR) analysis, respectively.
Results: Heat stress resulted in abnormal neurospheres development. The apoptosis rate was enhanced during long-term in vitro culture of neurospheres. Neurogenic differentiation reduced and showed aberrent phenotypes during heat stress. After hypothermia treatment significant improvement in neurospheres and neuronal cell morphology was observed.
Conclusion: Mild-hypothermia treatment induces attenuated heat shock response against heat stress resulting in induced HSP-70 expression that significantly improves structure and function of both undifferentiated human NPCs and differentiated neurons.
16. Morimoto, R. I, Tissieres, A., & Georgopoulos, C. (1994). The biology of heat shock proteins and molecular chaperones. New York: Cold Spring Harbor Laboratory Press.
33. Vishwakarma, S. K., Paspala, S. A. B., Bardia, A., Tiwari, S.K., Srinivas, G., Raj, A., et al. (2013). Isolation and characterization of neural precursor cells from different regions of human fetal brain: Assessment of in vitro proliferation and differentiation. International Journal of Advanced Research, 1(9), 782-793.


Avtohlamu - 6 of the most memorable music festivals of the 60s and 70s. The isle of wight music festival in 1970 was the last of three music festivals to take place on the island between the years of 1968 and 1970 the success of the first two events likely contributed to the huge turnout of attendees between 600,000 and 700,000 according to the guinness world book of records even more than at woodstock!. 4 of the most memorable music festivals galore. 4 of the most memorable music festivals pop; music festivals have changed a great deal since the fateful day of woodstock 1969 since that congregation of music, freedom and youth, festivals have become almost a rite of passage for the young and carefree a chance to forget the real world for one day and listen to the music that soothes. 6 most memorable 'fan on stage' moments mosh. Weekly music video roundup featuring awesome new tracks from the likes of lydia and milestones; 6 most memorable 'fan on stage' moments [tps header] we've put together a list of some of our most memorable moments that fans have been invited up on stage to play, sing and generally rock out with their favourite bands. Festival pass: the 14 most memorable festival moments of. Your friends here at the festival pass team went to a lot of festivals this year and that made our list of the most memorable moments a tough one to decide the mini music festivals at the. The 5 most memorable sets at electric forest music festival. Without further ado, here is my list of the most memorable sets keeping in mind that i could not catch them all 5 justin jay's fantastic voyage 5 low key music festivals to catch before summer ends sounds an enthusiastic account of houston's whatever fest sounds dispatches from fun fun fun fest culture. The 11 biggest music festivals of the fall, all across the. Here are the music festivals that you should be looking forward to for the rest of 2018 skip to content toggle navigation sounds; to be at this year, they decided to bring the carnival to orlando, florida nov 9 and 10 are going to be some of the most memorable dates for music fans who are able to attend the three different stages. Telluride jazz festival. The telluride jazz festival has consistently earned national and international attention for featuring the best in classic, mainstream, blues, african, cajun, and latin jazz music telluride jazz festival ranks among the world's most memorable music festivals. 6 most memorable in person nba draft moments seatgeek. Live music live sports live festivals search search 6 most memorable in person nba draft moments alex gormley june 23, 2017 in honor of a relatively tame evening in 2017, let's look back at some of the more memorable, in person draft night reactions. Uk festivals 2019 14 of the best cn traveller. Well rested from its 2018 fallow year, worthy farm is once again ready to host the world's most famous music festival glastonbury sets the bar when it comes to multi genre festivals and consistently books the industry's biggest names to play its pyramid stage. Who is the most memorable person you've met at a festival. Music festivals of any kind feel free to post news, pictures, lineups, upcoming shows, videos, ask questions, etc * bonnaroo * coachella *.


A bike polo photo book by Robert Griffin was published yesterday. It's titled Wheeled Horses – Chicago Bike Polo. Apparently it's 7″x7″ and 42 pages. A pre-view is available online at blurb.com or just click the image below.
This entry was posted by Doug D on August 24, 2008 at 12:01 am, and is filled under Art, Bike Polo, Illinois, Products. Follow any responses to this post through RSS 2.0. You can leave a response or trackback from your own site.


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Live: South side of the 6300 block of Hollywood Boulevard
Actor | Comedian
Born Jacob Cohen on Nov. 22, 1921 in Babylon, N.Y.
Died Oct. 5, 2004 of complications following heart valve replacement surgery in UCLA Ronald Reagan Medical Center, CA
Rodney Dangerfield tapped an enduringly rich vein of comedy gold when he created his stage persona as a middle-aged everyman who got no respect.
Dangerfield's successful comeback as a stand-up comic in the 1960s when he was in his 40s made him a familiar figure on television, in movies, and on Vegas and comedy-club stages for more than three decades.
Standing on stage in his trademark black suit, the bug-eyed Dangerfield was always the picture of sweaty unease, nervously tugging at his red tie as he delivered his sharply timed, self-deprecating lines.
In an hourlong performance, Dangerfield would do about 325 jokes, his stream-of-consciousness delivery and lovable loser persona combining to create one of comedy's most recognizable icons whose appeal spanned the generation gap.
At 19, he got a gig in the Catskills, the mountain resort area north of New York City — 10 weeks at $12 a week, plus room and board — and he legally changed his name to Jack Roy. He also was hired as a singing waiter at the Polish Falcon nightclub in Brooklyn, where Lenny Bruce's mother, Sally Marr, was the emcee. Earning $20 to $30 a week for three nights' work, he considered it his first break in show business.
After two years as a comic, Dangerfield was earning about $150 a week. But it was a constant struggle, and after working a series of what he termed "dumps," he gave up show business at 28 to marry Joyce Indig, a 23-year-old singer, "and lead a normal life."
It was while going through his divorce in 1962, a time when he was $20,000 in debt and living in a seedy New York hotel, that the 40-year-old Dangerfield decided to give stand-up comedy another shot.
It was slow going at first. The turning point came in 1967, when Dangerfield's agent arranged an audition for him with Ed Sullivan, whose Sunday night variety show was the premier television showcase for performers. Sullivan liked what he saw.
Dangerfield had been talking about how nothing goes right for him — a topic that perfectly suited his hang-dog, been-through-the-wringer demeanor. But before making the fourth of his 16 appearances on the Sullivan show, he recalled that the gangsters he saw in the clubs he worked at always talked about getting or not getting respect. The phrase, "I don't get no respect," would become the unifying theme of his act.
When he next appeared on the Sullivan show, he tried out a joke that defined his new comedy image: "When I played hide-and-seek, they didn't even look for me."
— Dennis McLellan in the Los Angeles Times Oct. 6, 2004
The Education Of Rodney Dangerfield
Rodney Dangerfield, 82; Comedic Icon Built a Career on Getting 'No Respect'
Three thoughts about Rodney Dangerfield
Yes, I was his nurse. I was his private nurse. I can't tell you where, but, Rodney was my patient. I was a nurse for alot of celebrities, can't tell you about their illnesses, but I know his wife Juan very well, she picked me to work with Rodney, because I got along well with him. He called me Big Black Momma, because I was so strict, he made a joke to all the producers, in the room, which included Louie Anderson, from the Family Feud, it was hilarious!!!
" — Demetrice Lee, March 27, 2010 at 3:41 p.m.
Yes this comical genius deserves a star, a lot of the classic 80's comedy movies starred him as the main actor.
" — ARMANDO CASTRO , October 6, 2015 at 8:43 a.m.
Total Respect!
" — Kate, October 6, 2015 at 4:09 p.m.
Share a thought about Rodney Dangerfield
Did you ever meet Rodney Dangerfield? Share your memory.
Which other stars on the Hollywood Walk of Fame have connections to Rodney Dangerfield?
Are other places in the world important to Rodney Dangerfield?
Does Rodney Dangerfield deserve this star on the Hollywood Walk of Fame?


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THE TUESDAY DROP: 4,100+ New Shots
12.13.22 Seasons greetings from ShotDeck! Check out all the shots we're dropping from films that fit the festive spirit below, and remember you can always request films for future drops by clicking here!
IN BRUGES (2008)
IN BRUGES is a 2008 Irish dark comedy crime thriller written and directed by Martin McDonagh in his feature directorial debut. The film stars Colin Farrell and Brendan Gleeson as two London-based Irish hitmen in hiding in Bruges, Belgium, from their enraged boss (Ralph Fiennes). In Bruges premiered at the 2008 Sundance Film Festival, and grossed over $34 million from its $15 million budget, earning an Academy Award nomination for Best Original Screenplay. McDonagh worked on the film with Danish cinematographer Eigil Bryld, whose body of work includes House of Cards, The Report and Deep Water.
The entire film was shot on location in Bruges, and McDonagh and Bryld wanted the visual language of the film to incorporate the city meaningfully into the story, given how much of the film is about these two characters dealing with the city in different ways. McDonagh and Bryld referenced the paintings of Hieronymus Bosch as a core reference point for the film, and wanted the movie to visually progress from highlighting the beauty and charm of Bruges, to eventually foregrounding its more foreboding, gothic qualities as the tone of the film darkens. Bryld achieved this through the precise lighting design that he and his department developed, lighting buildings and spaces with warm tungsten sources that were eventually taken away, with buildings being increasingly backlit to create frightening silhouettes as the characters end up in a race for their lives.
BATMAN RETURNS (1992)
BATMAN RETURNS is a 1992 American superhero film directed by Tim Burton and written by Daniel Walters, based on the DC Comics character Batman. The film stars Michael Keaton as Bruce Wayne / Batman, who comes into conflict with wicked businessman Max Shreck (Christopher Walken) and the Penguin (Danny DeVito). When Shreck's assistant, Selina Kyle (Michelle Pfeiffer) finds out about his plot, he tries to kill her, and she is transformed into Catwoman, whose efforts to team up with Schreck and the Penguin are complicated by the romance budding between her and Batman. Batman Returns was the sequel to the 1989 film Batman, and grossed over $266 million from its $50-80 million budget, earning Academy Award nominations for Best Makeup and Best Visual Effects. Today, it is considered one of the most successful entries in the Batman franchise. Burton worked on the film with American production designer Bo Welch, whose filmography includes Edward Scissorhands, The Birdcage, Men in Black and Thor.
Batman Returns was shot almost entirely across seven soundstages on the Warner Bros. and Universal lots. Welch and Burton wanted to extend the work done in the first film by Anton Furst, making the film feel as though it was taking place on the West Side of Gotham, while the first film took place on the East Side. Welch was influenced by the architecture and art of German Expressionism, as well as neo-fascist architecture for the villains, while also being influenced by painters from the American precisionism era. Welch's concept designs started with building cardboard models of buildings influenced by depression era machine-age art, aiming for a feeling of an overbuilt, oppressive representation of Gotham City's corruption. Buildings were constructed on the sound stage to feel massive when shot from specific angles, and while the majority of the film was shot in these environments, several panoramic shots (such as a shot traveling from Shreck's department store to its office) were created with detailed miniatures.
MEAN GIRLS (2004)
MEAN GIRLS is a 2004 American teen comedy directed by Mark Waters and written by Tina Fey, partially based on Rosalind Wiseman's 2002 non-fiction self-help book, Queen Bees and Wannabes. The film stars Lindsay Lohan as teenager Cady Heron, who joins a public high school in the Illinois suburbs after being homeschooled by her scientist parents in Africa. Cady quickly finds herself in the good graces of an elite group of students dubbed "the Plastics", led by Regina George (Rachel McAdams), and has to navigate the social hierarchies of school while holding onto her friendships. Amanda Seyfried, Lizzy Caplan, Lacey Chabert, Daniel Franzese, Jonathan Bennett, Tim Meadows and Tina Fey also star. Mean Girls grossed over $130 million from its $17 million budget, and has gone on to become widely considered one of the most influential high school films ever made, and one of the greatest films of the century so far.
Waters worked on the film with American costume designer Mary Jane Fort. The two wanted the costuming to have a timeless quality while also feeling appropriate to the setting of the film. Fort decided she could create this timeless look by looking both forward and back in terms of fashion trends. To look ahead, Fort studied trends in European fashion, and took those colors and shapes and modified them for a contemporary American lifestyle. To look back, Fort found that girls in high schools in the '50s would do their nails and hair and wear some of their best clothes to school, and took these cues as inspiration for the dress sense of the characters in the film. In order to ensure they felt contemporary, Fort and her team scoured teen magazines, and used those trends as a basis from which to set the Plastics apart from everyone else. Fort wanted Gretchen to look slightly sweeter, evoking cardigans into her wardrobe, and for Karen to feel like the follower, wearing a combination of what Regina and Gretchen were wearing. The costuming of the characters would evolve alongside the story for each character, and the clothes of Mean Girls became a fashion icon for over a decade to come.
THIS CHRISTMAS is a 2007 American Christmas comedy written, produced and directed by Preston A. Whitmore II. The film is named after the 1970 Donny Hathaway song of the same name and follows the Whitfield family. Matriarch Ma'Dere Whitfield (Loretta Devine) assembles the family for their first reunion in four years, but the family's ties start to strain when various secrets come to light, including Claude's (Columbus Short) military status, Quentin's (Idris Elba) debts and teenager Baby's plans to become a singer. Regina King, Delroy Lindo, Laz Alonso and Sharon Leal also star. This Christmas grossed over $49 million domestically from its $13 million budget. Whitmore worked on the film with Italian-American production designer Dawn Snyder, who was the production designer of projects such as On My Block, Best. Worst. Weekend. Ever. and What Remains.
One of the factors differentiating This Christmas from most other holiday family films for Whitmore and Snyder was the Los Angeles setting of the film, which created a setting for the film that did not include the traditional imagery of snow and cold weather that American audiences were used to associating with films about the holiday season. Whitmore and Snyder wanted to embrace this element of the film, choosing to shoot on location around the city for as much of the film as possible, as opposed to building on set, so that they could convey a sense of the weather and climate even for interior scenes. Snyder and the locations team spent a lot of time scouting homes around Los Angeles, and designed the house to feel like a character in the film, with each setting of the film dressed and designed to evolve with the story and the journey of the family as tensions begin to rise between them.
SHAZAM! (2019)
SHAZAM! is a 2019 American superhero film directed by David F. Sandberg, based on the DC Comics character of the same name. The film follows teenager Billy Batson (Asher Angel) as he is chosen by the ancient wizard Shazam (Djimon Hounsou) to be his new champion by saying the name "Shazam", allowing him to transform into an adult superhero (Zachary Levi) with various superpowers. Mark Strong and Jack Dylan Grazer also star. Shazam! Grossed over $366 million worldwide from its $80-100 million budget. Sandberg worked on the film with American costume designer Leah Butler, whose previous films include Paranormal Activity 3 and Annabelle: Creation.
Sandberg and Butler wanted every element of the Shazam costume to have some continuity with both the character's golden age comic book roots, as well as the mythology that informs it, incorporating ancient symbols into the design of the suit, as well as choosing materials and colors that informed the look of the character. Gold became a central character to the design, given that it allowed the suit to be designed by organic elements and not feel manufactured, as well as create an association between the suit and Greek associations with gold of the sun and the sacred masculine. The lightning bolt itself was created with a thin lighting element that had a remote adjustable dimmer, which allowed it to be used as a practical source in shots for Sandberg and cinematographer Maxime Alexandre.
DEVS: SEASON ONE (2020)
DEVS is an American sci-fi thriller television series created, written and directed by Alex Garland. The series stars Sonoya Mizuno as Lily Chan, a software engineer for a quantum computing company Amaya, run by Forest (Nick Offerman). Lily soon becomes embroiled in a mystery when her boyfriend dies on the first day of his new job at Amaya's secret development division Devs by apparent suicide. The series also stars Jin Ha, Zach Grenier, Stephen McKinely Henderson, Cailee Spaeny, Karl Glusman and Alison Pill. Devs was nominated for four Primetime Emmy Awards in 2020. Garland worked on the series with British cinematographer Rob Hardy and British production designer Mark Digby, both of whom are longtime collaborators of Garland's.
Garland and Digby spoke about creating a dynamic, evolving, almost living world for the set of the Devs building, turning scientific principles into geometric designs in keeping with the principles of the company that its scientific heart would also be its most magical and lyrical space. The vacuum-sealed building that has a pulsing gold interior housing the beating heart of a quantum computer was designed to be a dynamic set by Digby, who built this environment in close collaboration with Hardy. Garland's working style did not involve storyboarding. He would instead begin the day with rehearsals and then work out shot lists with Hardy on set, meaning that Digby's design had to be flexible from both a design and a lighting perspective. Digby designed the set to be lit almost entirely by the reflection of light coming out of the gold-plated walls, which were built with foam panels covered in 4" x 4" gold leaf pieces of paper. Digby designed LED remote-controllable lights to line the walls at different angles that, when controlled by an iPad, were able to pulse in different ways that helped give the sets different looks and feelings depending on the scene, as well as accommodate the camera language of a constantly moving camera that Garland and Hardy designed for the series.
MEET ME IN ST. LOUIS (2004)
MEET ME IN ST. LOUIS is a 1944 American Christmas musical film directed by Vincente Minnelli, and written by Irving Brecher and Fred Finklehoffe, based on the short stories by Sally Benson published in a novel under the same title. The film, divided into a series of seasonal vignettes, starting with Summer 1903, relates the story of a year in the life of the Smith family in St. Louis leading up to the opening of the Louisiana Purchase Exposition (more commonly referred to as the World's Fair) in the spring of 1904. It stars Judy Garland, Margaret O'Brien, Mary Astor, Lucille Bremer, Tom Drake, Leon Ames, Majorie Main, and June Lockhart. Meet Me in St. Louis was a critical and commercial hit upon its release, becoming the second-highest grossing film of 1944 (collecting over $12 million from its $6.5 million budget), and earning four Academy Award nominations. In 1994, the film was added to the US National Film Registry by the Library of Congress. Minnelli worked on the film with American cinematographer George Folsey, whose credits include The Great Ziegfeld, The Band Wagon and A Life of Her Own.
Meet Me in St. Louis was the first film of Minnelli's career shot on Technicolor. Minnelli and Folsey had a Technicolor consultant, Natalie Kalmus, on set, but the pair wanted to push the possibilities of the form and experiment with the images it could create. Critics of the three-color Technicolor system at the time felt that it could not provide clean focus, especially for distant scenes, given that the image was simultaneously captured by three systems that were then printed together to provide the color film for exhibition (called the "Technicolor imbibition process"). Folsey and Minnelli decided to play with this soft focus effect, including it in the visual language of the film to give the movie a soft, dreamy feel. The Technicolor imbibition process stopped being used in the 1970s, and though some filmmakers such as Martin Scorsese fought to revive it because the Eastmancolor prints would fade after a few years, the process was only revived for a decade in the 1990s before being completely abandoned in 2002.
LAST CHRISTMAS (2019)
LAST CHRISTMAS is a 2019 romantic comedy directed by Paul Feig. The film is named after the 1984 song of the same name and is inspired by the music of George Michael and Wham!. Starring Emilia Clarke and Henry Goulding, the film follows Kate (Clarke), a disillusioned Christmas store worker who starts falling for a mysterious customer named Tom (Goulding). Emma Thomspon and Michelle Yeoh also star. Last Christmas grossed over $123 million from its $25-30 million budget. Feig worked on the film with British production designer Gary Freeman, whose credits include Everest and Maleficent.
Feig and Freeman's vision for Last Christmas was to create a slightly fairy tale version of London that embraced an aesthetic of fairy lights, beauty and romance, while still understanding the limitations that shooting on location in central London would place on the look of the film and embracing a level of groundedness through the fantasy. These locations in central London were contrasted with the working-class neighborhoods, such as Kate's house in Isle of Dogs. The Christmas store was created with a combination of location and stage work, shooting partially at a store in Covent Garden and then recreating the interiors on a soundstage.
THE BEST MAN HOLIDAY (2013)
THE BEST MAN HOLIDAY is a 2013 American comedy-drama written, produced and directed by Malcolm D. Lee. The film is a sequel to Lee's 1999 film The Best Man, and stars Morris Chestnut, Taye Diggs, Regina Hall, Terrence Howard, Sanaa Lathan, Nia Long, Harold Perrineau, Monica Calhoun and Melissa De Sousa, all reprising their roles from the first film. The Best Man Holiday was a critical and commercial success upon its release, grossing $71 million from its $17 million budget and earning four NAACP Image Awards. Lee worked on the film with American costume designer Danielle Hollowell, who is also known for her work on films such as Girls Trip and Roll Bounce.
Hollowell and Lee set up rules for each characters' costuming based on their personalities and their journeys over the course of the story. The pair wanted to ground all the costume choices in the real world, and create a feeling that these characters would shop for their clothes at the same places that the audience would go, pointing Hollowell towards stores such as Zara, Topshop, J. Crew and Banana Republic as places to source costumes from. Shelby's look was defined as "strategically sexy", Mia's as "classic glamor", Robyn's as "fun eclectic", Jordan's as "business glam" and Candace's as "balanced but fun", while Lance's look was defined as "power player", Harper's as "casual cool", Julian's as "urban intellectual" and Quinton's as "world traveler", all of which formed the foundation upon which their clothes were sourced for the film.
THE CITY OF LOST CHILDREN (2019)
THE CITY OF LOST CHILDREN is a 1995 sci-fi fantasy film directed by Marc Caro and Jean-Pierre Jeunet. The film follows the elderly Krank (Daniel Emilfork), who has lost his capacity for dreaming and is attempting to fight death by stealing the dreams of children. Krank's cloned henchmen (played by Dominique Pinon) snatch 5-year-old Denree (Joseph Lucien) and attempt to steal his dreams, prompting his father, One (Ron Perlman) and Denree's 9-year-old friend Miette (Judith Vittet) to join forces in an attempt to save Denree. The City of Lost Children premiered at the 1995 Cannes Film Festival, and is considered a major entry in the steampunk genre. Caro and Jeunet worked on the film with French-Iranian cinematographer Darius Khondji, who is known for his work on films such as Se7en, The Immigrant and Uncut Gems.
Caro and Jeunet worked with Khondji to create a high-intensity visual language for The City of Lost Children that pushed the film firmly into fantastical territory while still evoking a kind of grittiness and groundedness that would contribute to the dystopian atmosphere in which the story takes place. Khondji made prominent use of close-ups throughout the film, helping to create a sense of claustrophobia in the frame, and creating a high-key, chiaroscuro lighting design that pushed the drama and intensity of every scene to its visual potential.
THE MAN WHO INVENTED CHRISTMAS (2017)
THE MAN WHO INVENTED CHRISTMAS is a 2017 Christmas biographical comedy-drama directed by Bharat Nalluri and written by Susan Coyne, based on the 2008 book by the same name by Les Standiford. The film stars Dan Stevens as Charles Dickens, who is suffering financial hardship in 1843, 4 years after the success of Oliver Twist and after writing 3 unsuccessful novels in a row. Desperate for a hit, Dickens finds real life inspiration to create the characters in A Christmas Carol. Christopher Plummer and Jonathan Pryce also star. Nalluri worked on the film with British cinematographer Ben Smithard, who is known for his work on films such as The Damned United, My Week With Marilyn and The Trip.
Smithard and Nalluri were clear on wanting to avoid the moody, dark, desaturated look of historical films that had become a cliché of the genre, wanting to focus more on the magic of following Dickens' thoughts and allowing the audience access to his mind over the course of the film. Smithard chose to use the Alexa Mini paired with Zeiss Ultra Primes and Angenieux zoom lenses, opting to light the shoot with Tungsten sources placed outside windows and filling rooms with smoke to evoke the period and not allow scenes to feel too contemporary, and as a way of evoking a magical quality to the light in each scene, with soft, warm light that pushed the film outside the expected territory for a historical drama.
THE TUESDAY DROP – 08.03.21
CINE GEAR 2022 WRAPUP


Oktoberfest Brunch ft. The Woodpeckers / Feedo @ Cairo Jazz Club 610 - Cairo Jazz Club 610, Al Guezira Plaza, Sheikh Zayed, Egypt.
Enjoy your favourite Saturday brunch and chill at Cairo Jazz Club 610 with The Woodpeckers and Feedo. Reservations at CJC are recommended, call 01008111330.


SIMCRO Ltd. Has Acquired ISL Animal Health & NJ Phillips Pty Ltd.
Hamilton, New Zealand – Simcro Limited, a leader in the global animal pharmaceutical delivery device industry, has acquired ISL Animal Health (Hamilton, NZ) and NJ Phillips PTY (Gosford, NSW, Australia) from Forlong & Maisey and the Maisey family of Hamilton, New Zealand.
The agreement is effective from 1 September 2015.
Simcro Executive Chairman, Will Rouse, said, "After the Riverside Company became our majority shareholder in 2013, we began looking for opportunities to exponentially grow Simcro's international market strength. We've been in discussions with ISL Animal Health and NJ Phillips for quite some time.
"Internationally, animal health companies are amalgamating at a rapid pace. These industry changes are creating opportunities for companies like ours. These opportunities, however, create the requirement to meet ever-increasing quality and compliance thresholds for our global customers.
All three companies are exporters and have strengths in developing and manufacturing devices and packaging solutions for the delivery of animal health pharmaceuticals and vaccines to global markets.
"Around the world, Simcro has a strong reputation as an industry innovator and, as a result of these acquisitions, we intend to do even more in this space. We have plans to invest in new technologies and solutions for the ultimate benefit of our global customers," Mr Rouse also said.
Mr Rouse said the company intends to use its newly created critical mass to increase its geographical footprint in key markets – primarily Latin America, Asia, North America and Europe.
"Long-term our primary goal is growth: growing opportunities for staff, growing innovation, growing exports and growing international market share. Our next step is working together as a new team to execute a strategy to achieve these aggressive growth targets," he explained.
Simcro will move its Hamilton operations across the city to a new building on ISL Animal Health's current site. NJ Phillips' office in Gosford, NSW, will remain in its current location.
Mr Rouse confirmed daily operations at the three companies will remain largely unchanged.
The companies chose not to disclose financial details of the acquisitions.


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BOC Sciences provides various toxins used as payloads for antibodies conjugation and form ADCs. Mitochondria are the powerhouse of the cells, which control bioenergetics, biosynthesis, metabolism, and signaling. Given the wide range of roles, mitochondria were studied extensively as a potential therapeutic target for various diseases, including cancer, diabetes, and neurodegenerative diseases. Mitochondrial dysfunction of cancer cells includes increased aerobic glycolysis, elevated ROS level, decreased apoptosis, and resistance to chemotherapeutic agents. On the other hand, normal mitochondria suppress cancer proliferation and increase drug sensitivity by inhibiting cancerous glycolysis and glucose uptake. Mitochondrion-mediated pathways have been identified as promising targets for various diseases.
Why BOC Sciences
Comprehensive one-stop antibody-drug conjugate service platform
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More information About Mitochondria
Mitochondria Characteristics
Mitochondria are organelles present in most cells and composed of two membrane layers. They are the energy-producing structure in cells and the central spot for aerobic respiration. Mitochondrion retains its own genetic material and system, but is limited in size as a semi-autonomous organelle. In addition to supplying energy to cells, mitochondria are also involved in cellular differentiation, information transmission, apoptosis, and the regulation of cell growth and cell cycle. Numerous mitochondrial features have been used to design novel mitochondrial targeting anticancer agents. Moreover, selective delivery of drugs to mitochondria improves drugs' specificity and reduces toxicity. A better understanding of the mitochondrial role in cancer development reveals possible therapeutic targets and improves mitochondria-targeted anticancer drugs' activity and selectivity.
Fig. 1. Structure of Mitochondria.
Mitochondria Inhibitor
Mitochondria in malignant cells differ from normal cells in structure and function, which are actively involved in metabolic reprogramming. Mitochondria in cancer cells are characterized by excessive reactive oxygen species (ROS) production, promoting cancer development by inducing genomic instability, altering gene expression, and participating in signaling pathways. Mensacarcin is a highly oxygenated polyketide first isolated from soil-dwelling Streptomyces bacteria. It exhibits potent cytostatic properties (mean of 50% growth inhibition=0.2 μm) in almost all cell lines of the National Cancer Institute (NCI)-60 cell line screen and relatively selective cytotoxicity against melanoma cells. Live-cell bioenergetic flux analysis confirmed that Mensacarcin disturbs mitochondrial function and energy production. Mensacarcin's unique mode of action suggests that it may be a valuable probe for examining energy metabolism, particularly in BRAF-mutant melanoma, and represent a promising lead for developing new anticancer drugs.
Plitzko, B.; et al. The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells. J Biol Chem, 2017, 292(51): 21102-21116.
Plitzko, B.; et al. Measurement of Oxygen Consumption Rate (OCR) and Extracellular Acidification Rate (ECAR) in Culture Cells for Assessment of the Energy Metabolism. Bio. Protoc., 2018, 20, 8(10): e2850.


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Q: How should I handle a HTTP response whose body takes time to generate, and whose headers cannot be determined until generation is complete? Background
My web application lives on a centralised server in the product's "network", and provides the means to manage/configure various distributed devices. The server also logs various statistics that arrive from each device, storing them on disk in /var/log/. The web GUI allows users to download those logs.
It also has a facility to download them in various different formats, which requires an on-the-fly translation/conversion. This conversion takes some time (say on the order of thirty seconds) and results in files of size in the 300MB region.
All of this is fine and a user can accept that downloading such a converted file is going to take some time. But I've architected myself into a bit of a corner in terms of how effectively I can actually deliver these files.
For the purposes of this question, I shall not be exploring AJAX/JavaScript/Java/Flash/multi-step/multi-page solutions. Assume that, from the user agent's perspective, the download shall be a straightforward HTTP GET request to a CGI script from clicking on an <a> element, and nothing more.

Problem
My web application is loosely MVC-architected in such a way that the controller chosen to satisfy the requested action (say, in this case: controller "devices" action "getConvertedLog") performs its business logic and sets various flags that describe how the HTTP response should be composed. Only after the controller has finished its work will the HTTP response be composed, with response headers generated and the body streamed from, in this case, a temporary file on disk.
The first problem with this is that the controller itself performs (or, at least, invokes) the file conversion, takes some time to perform. The HTTP headers are consequently not generated (let alone transferred) for thirty seconds or so. Not only does this result in thirty seconds of literally nothing happening in the browser (at least from my experience in Chrome) but it also puts the entire request at high risk of a HTTP 504 Gateway Timeout error from intervening routers.
I could shuffle my code around a little so that some HTTP response headers can be transferred to the browser before the conversion begins, to at least give an indication that something is happening (and, hopefully, stave off the Gateway Timeout). But before the conversion completes I have no way of knowing how many bytes will comprise the result. Therefore, I cannot send a meaningful Content-Length header, so the user-agent cannot display progress to the user. And for a 300MB file I do not consider this to be acceptable.
The second problem with this is that, if there is an error during conversion, the HTTP response code should be meaningful. So I cannot have sent a Status in these hypothetical pre-conversion headers.

Question
What would you do here? What's the least I need to do indicate to user-agents and proxies that the request has been accepted and a response is coming (albeit slowly), before the success or failure and size of the response has been determined?
I guess it would be ideal if it were legal and functional to send a very small set of headers, say:
 Status: 200 OK
 Content-Type: application/zip
 Content-Disposition: attachment; filename="thefile.zip"

… then follow it up with the remaining headers (Set-Cookie, Cache-Control, Content-Length and so forth), some potentially replacing earlier ones (like a change in Status) and, finally, the response body.
I'm hoping the fact that Apache's CGI module translates and re-orders some headers (e.g. Status: 200 ends up in the first line of the response as HTTP/1.1 200 OK) can help here. How might HTTP 102 Processing help here?
(Update: "At least one CGI-Header must be supplied, but no CGI header can be repeated with the same field-name." [CGI 1.1, §9.2]. Rats.)

A: This is a common problem.  The first example that springs to mind is in credit card authentication.
As has been mentioned, you need to conceptually fork the process, so that one thing responds to the client and another does the actual work.
This is actually quite straight forward, because HTTP is a state free protocol, you can have a page render, and complete the client transaction, whilst actually carrying on functioning on the server (as long as the service on the server allows you too, PHP will normally time you out if you take too long).
So here's a plan.  When you get your request, create your temporary file, with a name like /tmp/.part and redirect the client to a different page, which I'll come to shortly.  Either send the  as a parameter within the redirect link, or as a cookie.  Then conclude your connection with the client and process the file, storing data in /tmp/.part as you go.  Once you're done, rename /tmp/.part to /tmp/
On the different page, given  parameter (either from cookie or parameter), and check for the existence of /tmp/ or /tmp/.part  If the .part file exists, it's still processing, either generate a html file with a meta tag telling the user to reload in a few seconds, or sleep for a few seconds and give the client a redirect with the same form as the original caller.
If /tmp/ exists, you're done.  Present the user with the file for download.
You might also want to add some garbage collections somewhere to check if there are .part files that haven't changed for >1 hour, or actual files that are more than 2 or 3 hours old, and delete them.
If you have a server that is timing you out, then you have 2 options, via restart during refresh, or via cron.
If you opt for restart, code the .part file with enough information to pick up the process mid way through and have the refresh stage check for a running process and if it doesn't find one, restart the process
If you opt to go through cron, you're ultimately changing the above to a job management system, where instead of the cgi-bin initiating the work, you have it create the request, and have cron periodically checking for requests (the existence of a .part file) and where it finds one, it executes it.
Regarding error handling, this could feed into your ability to restart a process.  If the .part contains some status indicator, to tell the reload screen where it's at, you could pass error conditions back to the user.  If the executing script encounters a problem, it updates .part.  When the client next reloads the page with  as it's context, it looks at the .part file and returns back the status.
It's worth bearing in mind, you have to balance the complication of putting into .part more than simply the incomplete version of what will be  vs creating a 3rd file such as .status which the reload script might use.

redpajama_set_name: RedPajamaStackExchange


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Press Release - Detroit Man Charged in Carjacking and Armed Robbery Crime Spree
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Detroit Man Charged in Carjacking and
Armed Robbery Crime Spree
Wayne County Prosecutor Kym Worthy has charged Edward Mack Anderson, 27 (DOB: 07/31/1992) of Detroit, in connection with a series of crimes, including a carjacking, felonious assaults and armed robberies that occurred throughout Detroit between early February 2019 and late October 2019.
It is alleged that the defendant fired three shots at the female driver who had just exited the northbound Lodge Freeway at Wyoming Avenue.
Anderson has been charged with Assault with Intent to Do Great Bodily Harm, Carrying a Concealed Weapon, Felon in Possession of a Firearm and two counts of Felony Firearm.*
April 9, 2019 at approximately 5:37 p.m.
It is alleged that the defendant brandished a firearm at the same previous victim in the 15100 block of Greenfield Avenue in Detroit.
Anderson has been charged with Felonious Assault, Carrying a Concealed Weapon, Felon in Possession of a Firearm and two counts of Felony Firearm.*
September 28, 2019 at approximately 2:55 a.m.
It is alleged that the defendant carjacked a 27-year-old male and a 28-year-old female at a gas station in the 11600 block of Schaefer Avenue in Detroit.
Anderson has been charged with Carjacking, two counts of Armed Robbery, Receiving and Concealing Stolen Property - Motor Vehicle, Unlawful Driving Away of an Automobile, Carrying a Concealed Weapon, Felon in Possession of a Firearm and six counts of Felony Firearm.*
October 5, 2019 at approximately 12:10 a.m.
It is alleged that as a 53-year-old male was walking in the area of Tireman Street and Southfield Road, a vehicle pulled up and the armed defendant driver exited the vehicle and robbed the victim of his clothing and personal property.
Anderson has been charged with Armed Robbery, Carrying a Concealed Weapon, Felon in Possession of a Firearm and two counts of Felony Firearm.*
A 27-year-old male was walking in the area of Diversey and Mansfield when it is alleged that a vehicle pulled up and the defendant driver pulled a weapon, struck him in the head with the weapon and robbed him of his clothing and personal property.
October 9, 2019 at approximately 11:00 p.m.
A 20-year-old male was walking in the area of Scotten Street and Scoval Street in Detroit when, it is alleged, a vehicle pulled up and the defendant driver exited the vehicle, pulled a weapon and robbed the victim of his personal property.
October 24, 2019 at approximately 11:55 p.m.
An 18-year-old male victim was walking northbound on Cass Avenue near Selden when, it is alleged, the defendant driver pulled up on the victim, exited the vehicle and pointed a weapon at the victim. The victim was able to escape on foot.
The male victim was walking southbound on Second Avenue near Hancock when, it is alleged, that a car drove up on him, the defendant driver exited the vehicle, pointed a weapon at the victim and robbed him of his personal items.
Anderson was arraigned on these cases on October 28, 2019 before 36th District Court Magistrate Dawn M. White. The Probable Cause Conferences are scheduled for November 11, 2019 at 8:30 a.m.; the Preliminary Examinations are scheduled for November 18, 2019 at 9:00 a.m. All hearings are before Judge Ronald Giles in 36th District Court. The defendant was remanded to jail.
*The charges are allegations and defendants are presumed innocent until and unless proven guilty.
Kym L. Worthy
Wayne County Prosecutor


The Oconee County Technology department is dedicated to supporting the effective integration of technology into all aspects of teaching, learning, and school administration.
Students and parents in Oconee County expect the school system to provide a quality modern educational environment that will prepare their children for the modern world. Technological tools are vital to this process. Having access to real world tools helps students gain the technology skills needed to be lifelong learners and prepares them for successful careers. Parents can learn more about classroom technology and find additional resources by visiting the Parent Classroom Technology Guide page.
Technology is a tool for teachers and students. It increases student engagement, teacher productivity, content differentiation, and the amount of readily available student learning data. Interactive whiteboard and wireless tablet technology will be used to teach rigorous content in all content areas. Classroom response systems will be used throughout the middle and high schools to instantly assess if the students are learning the content being taught. The results of the assessments will inform and immediately change the instruction being offered. The response systems also help teachers identify individual needs of students. Computer benchmark assessments further enable teachers to gain information about individual student performance. Email and the introduction of VoIP classroom phones help teachers efficiently communicate with parents and other teachers.
Elementary students have access to modern computers in the classroom, media center, and computer labs. Shared network folders have been established for the students to save their work. Middle and High School students have access to modern computers in the computer labs and media center. All middle and high school students have logins and networked folders to save their work. This allows them to access their documents and files from any computer in the school. Students at all levels have the resources necessary to produce materials that demonstrate their acquisition of both basic skills and higher order thinking skills using modern technology tools.


Tana Wojczuk is a writing teacher, with a focus on the essay. Her classes often incorporate readings from American Studies and intersect with her work in cultural criticism. She teaches writing at NYU and formerly taught essay writing courses at Columbia University themed around American Studies and Writing and the Law.
Media: Interview with Phililp Lopate on "Making Your Essay Your Own" from The Morningside Review, Columbia's Journal of Undergraduate Writing.
I have a thought about this approach to essay writing where the writer is not wholeheartedly behind the essay. In other words, the author invents a character that has a point of view, a life of circumstances or experiences that he or she does not have or hold. Some one asked a question about the balance between creative essay writing and more formal styles and Mr. Lopate suggested that essay writing is inherently creative. But I think, while that may be true, it misses the point of the question, or at least the point as I heard it. If an essay writer invents a character to express a voice for a mind of ideas that are not his or her own it seems to me that this is simply fiction, a short story of sorts. It's not an expansion of the form but a blurring of the lines with an already well established form.
I mean, like, as if there is supposed to be a recognizable form at all. I'm imagining a three dimensional continuum, a cosmic Venn diagram, that all forms of writing would fit into and all their characteristics could be accounted for. The point of course is to allow for everything and anything, especially invention and origination, which are good things in my opinion. No form defined but by that which is taken is so defined. Something like that. But defined form is good too, obviously. And good form requires a mold, does it not? And if you break the mold, or change it in some important way, then what have you of the original form. It's is irrevocably changed, confused at least if not outright lost entirely.


text:
Divine Jokes
What do you get when Little Richard calls you up to tell you he's picked up Carmen Miranda, Freddy Mercury, Peter Allen, Divine, Sylvester, Chris Crocker, Elton John, Gil Chesterton, Andy Dick, Wayne Newton, Liberace, and Richard Simmons...and they're on their way?
Tutti Frutti en route-y!
(Wooooooooo!)
An American, Brit, and Aussie are about to get executed in Russia.
The executioner approaches the American prisoner and says, "How would you like to die? By firing squad, hung by the neck, or on the electric chair?"
"I'll take the chair" the American says. So he gets strapped into the electric chair.
When they flip the switch, nothing happens! In Moth...
Why doesn't anybody eat the toast after they see an image of Jesus?
I bet it tastes divine!
(A joke my physics teacher told) There was a Bulgarian man who drove trains for a living...
He loved his job. Driving a train had been his dream ever since he was a child. He loved to make the train go as fast as possible. Unfortunately, one day he was a little too reckless and caused a crash. He made it out, but a single person died. Well, needless to say, he went to court over this incid...
Israel Health minister who previously claimed that CORONA Virus is "divine punishment against homosexuality."
Has tested positive for the virus!!!
A good-natured conspiracy theorist wakes up and realizes that he's died in his sleep and gone to heaven...God appears and says "welcome my son, as a reward for your virtuous life, I can answer one question for you about any topic you'd like with absolute certainty..."
The man thinks for a second and asks God "who actually killed JFK?"
God's eyes roll back in to his head for a minute while he scours the divine historical record. After a moment, he returns to normal and says "Lee Harvey Oswald."
The man replies "Wow! This goes way deeper than I though...
What's the most divine chord?
**G Sus**
A 'divine' healer in his 'miracle' ministry called, "Anyone with 'special needs' who wants to be prayed for, please come forward to the front."
With that, John got in line and when it was his turn the Pastor asked, " John, what do you want me to pray for you?"
John replied, "Pastor, I need you to pray for help with my hearing."
The Pastor put one finger of one hand on John's ear, placed his other hand on top of John's head, an...
Why do Reddit astrologers not try to divine humor from the movement of planets?
Because the real joke is in the comets!
Is Hell endothermic or exothermic?
The e-mail was on the weighty matter of the nature of hell, as allegedly posed by a Dr Robert Shambaugh of the University of Oklahoma school of chemical engineering. It purports to be a final exam question from May 1997.
His May 1997 question for his Momentum, Heat and Mass Transfer II class ...
A man drives a train in Bulgaria. One day, he falls asleep driving and runs over someone walking on the tracks. Well, his case goes to court, and he gets the death sentence for murder
So, he's on death row and the executioner approaches him.
"What would you like for your last meal?"
"I would like a banana please."
The executioner thinks it's weird, but shrugs and gives him a banana. The guy eats his banana, waits a while, and gets strapped into the electric c...
The Home Minister, the Minister of Defence and the Minister of Fisheries are on a state visit to the Vatican.
As a courtesy, the Pope dines with them that night. The food is good, and the conversation still better. As the evening wears on, the Home Minister notices that her cup has run dry, and uses the opportunity to show off her inexhaustible wit. "Pope the divine," she says, turning to the solemn head of...
Several churches started having problems with squirrels damaging their buildings.
The Presbyterian church called a meeting to decide what to do about their squirrel infestation. After much prayer and consideration, they concluded that the squirrels were predestined to be there, and they should not interfere with God's divine will.
At the Baptist church, the squirrels had ...
KFC seeks divine intervention.
When I tell this joke, I change it to Colonel Sanders making the pitch and mimic his unique voice.
KFC Pope
A salesman from KFC walked up to the Pope and offers him a million dollars if he would change "The Lord's Prayer" from "give us this day our daily bread" to "give us this day our...
Three people die and appear before Buddha
Stunned by the divine presence before them, they lower their heads.
-Raise your heads. You were humble in life and your deeds were praiseworthy. You have earned the right to a reincarnation of your choice. You have much to accomplish yet though.
One of the people takes a step forward a...
This is a joke my dad told me a long time ago. I hope I don't offend anyone.
A young man was inspired to help out with his church's fundraiser. He asked the preacher if he could participate. The preacher, knowing the young man had a bad stutter, only gave him 3 bibles to sell.
The following day the young man returned asking for more. The preacher gave him 5. The follo...
Scientists found out that the cause for the California earthquake was not a divine retribution but simply a banana peel.
Your mom slipped over it.
How do you cook divine spaghetti?
Al Dante.
A priest is playing darts...
A priest is playing darts. Every time he misses he yells out: "Jesus Fucking Christ I'm pissed, my shot just missed!". A bishop sees him and warns him about using the lords name in vain. "If you use that language again, I shall ask the lord to punish you" he says. But the priest doesn't mind him and...
An enormously popular and beloved Pope, after a long reign, dies and, naturally, goes to heaven.
He's met by the reception committee, and after a whirlwind tour he is told that he can enjoy any of the myriad of recreations available.
The pope, having always loved the bible, decides that he wants to read all of the original records of God's communications with humanity before they were re...
Whoever wrote the Bible should've come up with two more divine entities
So instead of calling it the "Holy Trinity" it would be the "Repentagon".
Did you hear about the hornet who left home in search of the divine truth?
He's a bee-leaver
A man has a parrot that likes to swear.
One night, a girl he's been dating for a while, is coming over to his place. So he grabs the parrot by the neck and tells him
"Listen you little shit, no swearing tonight, alright!? Also I will tie two string on your legs, and when the girl pull one of them I want you to come up with a compl...
The Pope is saddend that he never sees much of the countries he visits and decides it's time for a change
After a visit to Berlin, the Pope decides he wants to travel to Rome by car. Off course, he didn't bring a car and so the German government seizes the opportunity to impress him with German engineering. They lend him the most powerful car they have available, with a German driver/bodyguard. And off ...
It's the time of the French Revolution and they're doing their usual daily beheadings..
Today they're leading a priest, a prostitute and an engineer up to the guillotine.
They ask the priest if he wants to be face up or face down when he meets his fate. The priest says that he would like to be face up so he will be looking toward heaven when he dies. They raise the blade of the ...
Long Joke
Ever since he was a little kid, Bob always had one goal in life: to become a train conductor. Finally when he grew up, he achieved his goal and became the conductor of the Happytown train. He was so excited to conduct the train that he decided to see how fast he can go. He went faster and faster unt...
The tale of timmy.
When little Timmy went to school,
and Mastered one to nine,
He thought the other kids were cool,
and every class divine.
He painted shapes in red and blue,
and drew in curves and bends,
and by the time the day was through,
he'd made a hundred friends!
I'm pals...
So Johnny dies and goes to heaven, where god's waiting to review his life.
God's all like "Aight, aight. I like you Johnny, I always have, always will. You helped old ladies cross the street, you donated to charities, and all in all in my professional divine opinion.... you're a stand up guy! But what the fuck's the deal with all the incest porn?"
Johnny replied, " ...
Two Priests and Two Nuns have dinner with His Holiness, the Pope.
Two priests are fishing on lake outside of Rome. It's a beautiful day, the sun is light, and the water is smooth. Suddenly the first priests fishing rod bends alarmingly; he has hooked a huge fish! It's a struggle but he managed to reel it in. It's a beautiful rainbow coloured fish and big enough to...
Three kingdoms border a lake in the shape of an obtuse triangle
One kingdom lies on each side of the lake. For decades, the king's had argued over it's true owner, each claiming to be the first kingdom to settle there, and many tales of magical swords and godly favours to claim divine right. Eventually, this storytelling and legal battling came to no conclusion,...
A long time ago, in the middle east
There was a town where everyone worshipped many gods. But one day, a young boy arrived from afar, claiming to be a prophet sent by Allah. He told them to convert to Islam, or else they would receive divine punishment.
Naturally, the townspeople rejected his words, and they executed him in pub...
Franz was reading his book on death row...
It was the 'storm of the century'. On death row, Franz was reading his religious texts, looking for God, even as the inmates of the neighbouring cells were having an explosive argument about who should get to shower first. '14 days to execution', Franz thought, as he physically and mentally trembled...
I was in the dentist's chair.
He looked at my shoes and said, "Very nice loafers there, very nice."
"Thanks," I said.
Then he looked at my leather bag. "Love the bag, too. Very stylish, very nice."
He looked out the window while I rinsed my mouth out, and said, "That car is divine. I...
Flood joke from a catechism
Religious guy's town started flooding, and when the water reached his porch he started praying for help. Suddenly, a divine voice told him, "Bob, you are a good person, I have heard your prayers and I will save you!"
A few minutes later some woman in a small inflatable raft paddled by.
Suzy came to the church in a see-through blouse leaving nothing to imagination
After the congregation,the priest called her aside and said " you can't come to church dressed like that " pointing at her blouse.
"But I have a divine right" complained Suzy.
" And you have a divine left too " noted the priest " still you can't come dressed like that " .
A huge soccer fan arrived at the Vatican
There, he saw the pope. He approached His Holiness and said: 'Mr. Popeman, there is one thing I have always wondered: do they have soccer in heaven?'
'Good question', says the Pope, 'Let me get back to you on that. Meet me here in a week.'
A week later, the Pope and the man meet each o...
There once was a wise old man...
There once was a wise old man in a village. Old beyond memory, he channeled the knowledge of nature and the divine for his fellow townsfolk.
Many came to him with questions, until one day he took a vow of silence, shuttering his open door. Instead, he turned to his untended field. He wou...
A father had a very rowdy son
He would never listen to his father, always disobeying rules, and being rebellious at every chance. The father often told the boy, "You should be more respectful of others", to no avail as his words fell on deaf ears. His pranks were, quite frankly, annoying to the neighbours, but what did the son c...
What is a synonym for the Holy Trinity?
The divine threesome.
During the French Revolution a doctor, a lawyer, and an engineer were facing execution on the guillotine.
The doctor was first, but the blade jammed and the doctor was set free due to Divine Intervention.
The lawyer was next, again the blade jammed, and was also set free.
As the engineer was being led to his doom, he glanced up at the blade and said "Wait a minute! I think I see the proble...
The priest, laywer, and engineer
By chance, a priest, a laywer, and an engineer find themselves in line to be guillotined. They demand that the priest steps up, and he reluctantly does so. They put his head in the guillotine and pull the rope, but to everyone's surprise, nothing happens. The priest declares that he was saved by ...
How to use religion to your advantage
1. Claim divine visitation of some nature
2. ???
3. Prophet
Mix-up in Heaven
A bus full of people, all of whom were incredibly unattractive, crashes over a cliff. Everyone dies. They all ascend to Heaven. While waiting at the gates, God himself comes to greet them. "Hey, sorry about that. I know you weren't expecting to go that way. But you, know... divine plan." He proceeds...
Every year at the state fair...
... Paul entered the lottery for the brand new truck and lost. This year, he told his friend David, he wasn't going to bother and enter.
"What kind of attitude is that?" David asked. He leaned closer and whispered, "What you need, pal, is faith. Look around and see if the good Lord sends you...
Letter to God
A Post Office worker at the main sorting office finds an unstamped, poorly hand-written envelope addressed to God. He opens it and discovers it is from an elderly lady, distressed because some thief robbed her of 100 dollars. She will be cold and hungry for the rest of the month if she doesn't recei...
Russian version of the guillotine joke (different punchline)
(fyi: Russian belief is that if anything goes wrong during the execution, it is divine intervention, and it is every bad mojo to try to execute a 2nd time if the prisoner survived.)
The Germans catch 3 spies in Berlin during WW1. A Frenchman, an American, and a Russian. They wan...
Religious jokes can be funny
A Jewish man goes to his neighbor and tells him that his son ran away and became a Christian. The neighbor replies, "You know, it's funny you say that. A little while ago my son did the same." At that, they both went to the local rabbi to ask for guidance. When they tell the rabbi their stories, the...
I found this short, thin stick covered with flammable chemical at one end.
I rubbed it firmly against a rough surface. Suddenly I felt completeness and purpose in life. All the negative feelings such as bitterness and hate melted away. I started to see divine beauty around me and I was able to forgive everything. My mind was still. As I looked around me, I noticed there wa...
A 54 year old woman had a heart attack & was taken to the hospital
A 54 year old woman had a heart attack & was taken 2 the hospital.
While on the operating table she had a near death experience.
Seeing God, she asked, "Is my time up ?"
God said, "No, you have another 34 years to live."
Armed with this divine insight, the woman decid...
The train driver.
Once upon a time there was a guy that was very passionate about trains ever since he was a little kid.
So no one was surprised that once he grew up he became a train conductor.
However as much as he loved trains he was really terrible at driving them.
Sadly, one day he caused a ...
A man was walking by a construction site when he heard a woman yell "STOP!!!" The man stopped abruptly, and seconds later a brick fell and landed in his path. He looked around but saw no trace of the woman whose voice he heard.
A day or two after that, he was driving to work. In the midst...
A programming genius named Sewter
Built a limerick-writing computer
The metre was fine
And the rhymes quite divine
But for some reason it always got the last line wrong
Three guys are about to be executed.
One's a lawyer, one's a priest, and one's an engineer.
They bring out the lawyer first, put him under the guillotine, and pull the lever, but the blade gets stuck halfway down. The lawyer goes, "Ah-ha! By pulling the lever, you have technically carried out the execution, which according to th...
The creation of a pussy, improved version.
Each man was a master-of-craft at his trade,
Now by God in his wisdom a task they'd been laid.
See them gathered together, by calling divine
to fashion a vulva of peerless design.
The first man, a butcher of eminent skill
took a hold of his bla...
Intrepid Engineer
A Christian, a Muslim, and an engineer are sentenced to die at the guillotine.
The Christian goes first but when the executioner pulls the lever to release the blade, the blade suddenly stops halfway down the track with a loud "boing."
"Praise the Lord," the Christian exults, "who in h...
There is a huge queue of nuns at the gates of heaven
At the steps of heaven, Petrus is standing in front of a gate with a bucket of water besides him.
In front of him is a huge queue of nuns, all wishing to enter the divine realm!
Petrus looks at the nuns and shouts "Listen up all of you who have served God so well. Before you enter Heaven, ...
A farmer is having a bad harvesting season.
Nothing grew. He's trying to think about how to break the news to his wife and kids. They'll lose the house. They could starve. They spent so many hours tilling the fields and breaking their backs and they have nothing to show for it. He thinks of all the hours of his children's youth that he stole ...
divine intervention
heavenlygodsacredjehovahgodlikedeityholyprophecyalmightysuperhumanspiritualeternalcreatorinspiredsupernaturallordevildivinityspiritsupreme beinggloriousresurrectiontruthgoddesssalvationsoulimmortalityclericecclesiasticheavengod almightyomnipotentomniscientvisionangelicmiracleblessingspantheonmysticalchristsaintoraclezeusearthlyjesusessenceimmortalmiraculousdemoniceverlasting


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Toronto Film Review
Toronto Film Listings, Reviews and Criticism.
100 Best Canadian Films – Piers Handling
The reputation of Piers Handling precedes him: not only is he the director of TIFF but also a passionate cinephile and a valuable supporter of Canadian cinema. This includes having published two books on some of Canada's most important directors: Donald Shebib and David Cronenberg. Other contributions to 100 Best Canadian Films include those by Marcel Jean, Mike Hoolboom and myself. They're meant to be fun, subjective forays into the history of Canadian cinema. I'm also excited to to highlight the great new TIFF Canada on Screen website where many of these films are beautifully described and illustrated. There's more to come! – D.D.
Piers Handling's 103 Best Canadian Films
- Back to God's Country (David Hartford, 1919)
- Carry on Sergeant! (Bruce Bairnsfather, 1928)
- Rhapsody In Two Languages (Gordon Sparling, 1934)
- Churchill's Island (Stuart Legg, 1941)
- Listen to the Prairies (Gudrun Parker, 1945)
- Neighbours (Norman McLaren, 1952)
- Corral (Colin Low, 1954)
- Paul Tomkowicz: Street-railway Switchman (Roman Kroitor, 1954)
- City of Gold (


This super cool family met me at the historic Cambridge Fall Fair on a gorgeous late summer night for some rides and smiles. I loved the idea of heading to the fair - the lights, the roller coasters, the small of cotton candy, popcorn and caramel apples in the warm air, the laughter of delight and screams of terror, all underscored by a local band rocking the main stage. A perfect end note to summer. I really wanted to do my best to capture this awesome family as they truly are, loving, kind and truly bonded. They had a blast carnival games and riding the various amusement rides, stopping for a few quick photos in front of the fun house and then wrapping it up with some cotton candy and a few more stomach-twisting turns on the Tilt-a-Whirl as the fair's bright lights started to light the night sky.
Thank you all for being such great sports and for spending a great evening with me at the fair. Enjoy the images!