Option 1: What are the important elements of building a loving, safe, and supportive community? How do you contribute to maintaining these elements in your community?
"Define community," I hear my teacher say. All around me, students start scribbling furiously. Some run to the dictionaries, but my thoughts whirl around just two words: define community? How can you define something so abstract and complex? A dictionary alone cannot even begin to capture the essence of community. In fact, to really define community, you'd need to dive in.
Find a new community, one that you don't already belong to, and observe. Watch how every member treats one another with respect and kindness. See the initial discomfort between the members begin to dissolve and melt away. Study the way that each small misunderstanding leads to smiles and laughs. Look closely at the feeling of security, that safeness, but don't forget the struggles.
Scrutinize the flashes of the eyes, the forced smiles, and the strained laughs. Pay attention to the slightly raised voices, on the threshold of a shout. Keep an eye on those tense moments of rivalry, where the bystanders freeze and the participants pause, shaking slightly. Note how few community members go out of their way to avoid conflict. Realize that some conflict is inevitable.
Witness the moments when someone backs down. Mark the second when they suddenly realize it's not worth it. Observe how they stop themselves, often mid‐phrase, and politely agree. Recognize when they move along, ashamed, pretending that nothing happened. These moments are common yet invaluable to a good community.
"All right, you should be finishing up by now," the teacher says. Students sigh and pass their sheets forward. I quickly jot down some notes about kindness and respect, and pass up my own. But my mind still revolves around those two words. I see myself trapping that word, that word community, and snaring its lifeblood to impose onto paper. I envision myself truly defining community.
Come to my school, walk into my homeroom. You will start to notice. Peek through the window of my math class; slip through the doors of my Chinese class. There it is again! Sneak into science; stay quiet in the library. Spot those glimpses, those tiny flashes, of something much, much bigger. The colossal idea again.
We all have that special part of us: that thrill at an inside joke; that feeling when you look up from a task and see someone else looking up too; that shared awareness when you've been working as one seamless unit for hours, tirelessly, never once considering giving up; that simple pleasure when someone finishes your thought exactly, and you both turn and smile because good minds think alike! We all have our communities, and that concludes my definition.
To create a loving, safe, and supporting community, there must be meaning in everything we do. Each person works toward a common, greater goal, and each person thrives off the others. The elements that create this kind of community are insight, optimism, communication, responsibility, acceptance for growth, commitment, honesty, cooperation, compromise, awareness, organization, unity, and resourcefulness. All of these elements connect with each other. The relationship between these elements is that they all bounce off of each other in a cause‐and‐effect way. For example, when communicating your ideas in a group, you learn to compromise and work toward one outcome.
In my community, I contribute to maintaining these elements by involving myself in the action. When the time is right, I voice my opinion, provide ideas to the problems that we try to resolve, and ultimately work toward a common goal with my fellow peers. When I do this, it helps keep the flow of the community going and helps provide support to maintain the goal and efforts of others. The elements of a community are crucial pieces to a place and experience where everyone works hand‐in‐hand. Community doesn't function with just one person or thing, but is a collage of many different mixes.
There are times when I walk into a grove in the forest and see all these creatures vigorously and robustly conducting their lives yet interacting with one another so peacefully and tranquilly. The birds are tweeting; the leaves are shuffling; the brooks are rolling. There stands a doe, fixing her impenetrable vision on me as if she is telling a story of the silent forest that grows around us.
There I have a vision of the far ancient memory of our planet. Back then, there were only trees and waters covering the surface of our planet, the mother of earth. It was primitive, rough as well as dangerous in the wilderness of nature. But, as I remember, it was not evil. No, no evil. Surely creatures consumed one another for survival. However, as I looked back, I saw no violence but harmony, like a symphony played by the orchestra of the grand nature. It is in this way that everything—all living creatures—survived and prospered infinitely without an end.
As I roamed about within those lofty trees so high that they plunged into the sky, there was a feeling, an emotion that sprung from my heart, from my very essential being that I am not alone again. I seemed to be in a river, a life stream where I was flowing with millions of millions of others like countless plankton, together toward the very end. Right at that moment, I felt that I needed defense no more but only trust, a firm belief that the stream all of us are in will carry us to the ultimate purpose.
It was the community of God. It was just exactly the community of God that weighed down all man‐made artificial community, where conflicts exist but harmoniously. This must sound so strange but believe me, it is always possible for conflict to exist peacefully and harmoniously, only if we be a part of one another.
In a community, a group needs diverse and unprejudiced people in order to achieve unity and understanding. Without different ideas and opposing concepts, a community would not be able to move forward and grow like a garden to spread ideas or even understand other groups. Communities need to accept different and diverse ideas in order to agree, make decisions, and function. Although a community needs to have a variety of different people, it might also need a great deal of unprejudiced people, because we, as people, have different ideas, and we need to be able to understand those ideas without bias so we can have empathy and understanding. If there were to be a lack of open‐minded people, the communities would be unable to grow. Without acceptance of different or diverse ideas, the community would be unable to function or make decisions that benefit the group due to lack of agreement. Therefore, a community needs both a diverse set of people and a nonjudgmental mentality, or else the community can never grow and make a difference.
These are awesome people, every one. I'd love to see them in my community!


Please add sound. Your almost at five stars from me just needs sound.
Potentially the best stop motion app for the iPad, but needs work. The settings selection has buttons for quality and size. You have to hold the quality button down because a simple tap closes the app. It's not possible to operate the size button without closing the app, so I can't change from default small to large size. You actually have to save a video ( and describe it!) before deleting it and this is a pain. The grid and ghost image of the last frame are features of the great Mac app, iStopMotion. Adjustability of frame rate and time interval is easy. A nice loud click when a frame is recorded is welcome if you have used one of the silent types. Cool effects features are another plus. Imaginative displays for controls is yet another ( it would be better if all of the controls actually worked.) I hope that these problems will be corrected before I send this to the failed app graveyard.
This is the best video app ever.. It works good for Lego to be creative!
The best Stop Motion app Just wish there was no limit to how many frames you can do.


At Amp, we are passionate about making sure our artists are able to write the best songs they can by giving them access to some of the best songwriters out there.
To learn more about our songwriting camps, go to experiencesongwriting.com.
One of our songwriting coaches, Shane Stevens, has worked with artists like Carrie Underwood, Lady Antebellum, Jordin Sparks, and Megan Trainor. He was kind enough to sit down with us at one of our recent Nashville camps and give us his top tips for writing a good song.
Click here to watch the full interview with Shane Stevens!
Shane's biggest piece of advice is to be honest and share your own story. Write what you know, because that is what people will believe.
Once you've started writing your story, challenge yourself to write lyrics that you haven't heard anyone else write. "As we like to say in country music, put furniture in it!" is how Shane puts it!
His third tip is to be interesting melodically and to try new things. His encouragement is to push yourself! This, he says, is what will get people interested in your music!
Have other songwriting tips to add? Let us know in the comments! If you found this article helpful, don't forget to share it!


Give your tired eyes some love to protect your sense of vision.
Whether you're spending one month at a yoga teacher training or vagabonding around the country for months, this list will help you to be perfectly prepared for your journey.
When wanderlust strikes, pack your passport and flow with the universe's guidance.


text:
La psiquiatría biológica o biopsiquiatría es una rama de la psiquiatría que intenta comprender los trastornos mentales en términos de la función biológica del sistema nervioso. Es interdisciplinaria en su enfoque y se basa en ciencias tales como la neurociencia, la psicofarmacología, la bioquímica, la genética y la fisiología. Así pues, es la rama de la medicina que se ocupa del estudio de la función biológica del sistema nervioso en los trastornos mentales.

Si bien existe cierta superposición entre la psiquiatría biológica y la neurología, esta última especialidad se centra, por lo general, en los trastornos donde es evidente una patología del sistema nervioso, como la epilepsia, parálisis cerebral, encefalitis, neuropatía, enfermedad de Parkinson y esclerosis múltiple. Asimismo, hay cierta superposición entre la biopsiquiatría y la neuropsiquiatría, que se ocupa de los trastornos de conducta en el contexto de un aparente trastorno cerebral. La psiquiatría biológica y otros enfoques en las enfermedades mentales no son mutuamente excluyentes, sino que simplemente hacen frente a los fenómenos desde diferentes niveles de explicación.

Debido a su enfoque en la función biológica del sistema nervioso, la psiquiatría biológica ha sido importante en el desarrollo y la prescripción de tratamientos con fármacos para los trastornos mentales. No obstante, en la práctica, los psiquiatras pueden defender tanto la medicación como las terapias psicológicas para el tratamiento de las enfermedades mentales. Es más probable que la terapia sea llevada a cabo por psicólogos clínicos, psicoterapeutas, terapeutas ocupacionales u otros trabajadores de la salud mental, quienes están más especializados y entrenados en enfoques que prescinden de los fármacos.

La historia del campo data del médico de la Antigua Grecia Hipócrates, pero el término «psiquiatría biológica» fue usado por primera vez en la literatura científica arbitrada en 1953. El término es usado más comúnmente en Estados Unidos que en otros países como el Reino Unido; sin embargo, la rama no está exenta de críticas y la frase «psiquiatría biológica» es empleada algunas veces por sus críticos como un término despectivo.

Alcance y definición detallada

La psiquiatría biológica es una rama de la psiquiatría, cuya atención se centra principalmente en la investigación y la comprensión de las bases biológicas de los trastornos mentales graves, tales como los trastornos unipolar y biopolar (del estado de ánimo), esquizofrenia y trastornos mentales orgánicos, como el Alzheimer. Este conocimiento ha sido obtenido por medio del uso de ciencias de la imagen, psicofarmacología, neuroinmunoquímica, entre otros. El descubrimiento de la interacción detallada entre neurotransmisores y la comprensión de la huella digital de los neurotransmisores de las drogas psiquiátricas, como la clozapina, ha sido un resultado útil de la investigación.

A nivel de investigación, incluye todas las posibles bases biológicas de la conducta: bioquímica, genética, fisiológica, neurológica y anatómica. A nivel clínico, incluye diversas terapias, como medicamentos, dieta, evitar contaminantes ambientales, ejercicio y reducción de los efectos adversos del estrés, todo lo cual puede causar cambios bioquímicos mensurables. El psiquiatra biológico considera todas ellas como posibles remedios o etiologías para los trastornos mentales. No obstante, el psiquiatra biológico no suele descartar los enfoques psicoanalíticos (psicoterapia). Generalmente, la capacitación para los psiquiatras biológicos incluye tanto enfoques psicodinámicos como biológicos. Por consiguiente, los psiquiatras suelen estar cómodos con un enfoque dual: «métodos psicoterapéuticos... son tan indispensables como la psicofarmacoterapía en una clínica psiquiátrica moderna».

Fundamentos
A fines de los años 1950, las primeras drogas antipsicóticas y antidrepesivas modernas fueron desarrolladas: clorpromazina (también conocida como torazina), el primer antipsicótico ampliamente utilizado, fue sintetizado en 1950; mientras que iproniazida, uno de los primeros antidepresivos, fue sintetizado por primera vez en 1957. En 1959, fue creada la imipramina, el primer antidepresivo tricíclico,

Sobre la base de las observaciones clínicas de los resultados de las drogas mencionadas, en 1965, el artículo pionero The Catecholamine Hypothesis of Affective Disorders fue publicado. En él, se articulaba la hipótesis del desbalance químico para explicar los trastornos de la salud mental, especialmente, la depresión. Formó buena parte de la base conceptual para la era moderna en la psiquiatría biológica.

Esta hipótesis ha sido extensamente revisada desde su advenimiento en 1965. Investigaciones más recientes señalan los mecanismos biológicos subyacentes como la base posible para varios trastornos mentales.

Las imágenes modernas del cerebro permiten un examen no invasivo de la función neuronal en pacientes con trastornos mentales; sin embargo, esta opción es todavía experimental. Con algunos trastornos, parece que las imágenes pueden detectar con fiabilidad ciertos problemas neurobiológicos asociados con un trastorno específico. Si futuros estudios corroboran estos resultados experimentales, el diagnóstico futuro de ciertos trastornos mentales puede ser agilizando usando tales métodos.

Diagnóstico
El diagnóstico correcto es importante en los trastornos mentales; de lo contrario, la condición podría empeorar y tener como consecuencia un impacto negativo tanto en el paciente como en el sistema de salud. Otro problema con un mal diagnóstico es que un tratamiento para una condición puede exacerbar otras condiciones. En otros casos, trastornos mentales aparentes podrían ser un efectos secundarios de un problema biológico serio, como una concusión, tumor cerebral o anomalía hormonal, que podría requerir intervención médica y quirúrgica.

Tratamientos empleados
 Trastorno afectivo estacional: fototerapia, inhibidores selectivos de la recaptación de la serotonina.
 Depresión: Inhibidores selectivos de la recaptación de la serotonina (Prozac), inhibidores selectivos de la recaptación de serotonina y noradrenalina (venlafaxina), antidepresivos atípicos (bupropion, mirtazapina), antidepresivos tricíclicos, inhibidores de la monoaminooxidasa, terapia electroconvulsiva, estimulación magnética transcraneana.
 Trastorno bipolar: carbonato de litio, ácido valproico, lamotrigina, carbamazepina.
 Esquizofrenia: haloperidol, clozapina, olanzapina, risperidona, quetiapina, ziprasidona y otros antipsicóticos
 Trastorno de ansiedad generalizada: inhibidores selectivos de la recaptación de la serotonina, benzodiazepinas, buspirona
 Trastorno obsesivo-compulsivo: clomipramina, inhibidores selectivos de la recaptación de la serotonina (citalopram)

Últimos hipótesis biológicas de trastornos mentales
Nuevas investigaciones indican que diferentes mecanismos biológicos pueden ser la base de algunos trastornos mentales, solo indirectamente relacionados con los neurotransmisores y la "teoría del desequilibrio químico".

Una investigación reciente señala que podría existir una "vía final común" biológica entre la terapia electroconvulsiva y las drogas antidepresivas actuales. Esta investigación muestra que la depresión recurrente puede ser un trastorno neurodegenerativo, lo que altera la estructura y función de las células cerebrales, destruyendo las conexiones de las células nerviosas, incluso matando a ciertas células del cerebro y precipitando un declive en el conjunto de las funciones cognitivas.

En esta nueva perspectiva de la psiquiatría biológica, la plasticidad neuronal es un elemento central. Más evidence apunta a que varios trastornos mentales son un problema neurofisiológico que inhibe la neuroplasticidad. Esta es denominada la hipótesis neurogénica de depresión, que pretende explicar la acción farmacológica antidepresiva, incluyendo el lapso de tiempo entre la toma de la droga y el inicio del impacto terapéutico. Asimismo, se propone entender por qué la regulación a la baja de neurotransmisores pueden ayudar a la depresión, por qué el estrés a menudo precipita los trastornos del estado de ánimo y por qué la modulación selectiva de diferentes neurotransmisores puede ayudar a la depresión. También podría explicar el mecanismo neurobiológico de otros efectos no farmacológicos en el humor, incluyendo el ejercicio, la dieta y el metabolismo. La identificación de la "via final común" neurobiológica que comparten la mayoría de los antidepresivos podría permitir el diseño racional de nuevos medicamentos que se centren en esta vía, lo que podría producir drogas con menos efectos secundarios, más efectivas y de impacto terapéutico más rápido.

Críticas

Una minoría de pacientes, activistas y psiquiatras critican que la psiquiatría biológica sea un concepto científico o que tenga un base empírica adecuada; por ejemplo, argumentan que no existen marcadores biológicos de las condiciones psiquiátricas reconocidas. Esta posición ha estado representada en algunas revistas académicas como The Journal of Mind and Behavior y Ethical Human Psychology and Psychiatry, que publican material que contradice específicamente «la idea de que la angustia emocional se debe a una enfermedad orgánica subyacente.» En su lugar, teorías y modelos alternativos consideran los trastornos mentales como no biomédicos que pueden ser explicados en términos, por ejemplo, de las reacciones emocionales a las circunstancias negativas de la vida o a un trauma agudo.

Campos tales como la psiquiatría social, la psicología clínica y la sociológica pueden ofrecer explicaciones no biomédicas de los trastornos mentales para ciertas dolencias y, a veces, son críticos a la biopsiquiatría. Los críticos sociales creen que la psiquiatría biológica no ha podido satisfacer el método científico debido a que creen que no existe evidencia biológica falsable de los trastornos mentales. Luego, estos críticos consideran que la psiquiatría biológica es una pseudociencia que intenta retratar a la psiquiatría como una ciencia biológica.

Ronald David Laing sostiene que atribuir los trastornos mentales a los factores biofísicos era a menudo viciado por el procedimiento de diagnóstico: las pruebas complementarias (EEG, PET) suelen realizarse después del diagnóstico, cuando ya ha comenzado el tratamiento, lo que hace que las pruebas no sean ciegas y que incurran posiblemente en un sesgo de confirmación.

Véase también
 Psicobiología

Referencias

Enlaces externos

Modelos médicos
Biologica

redpajama_set_name: RedPajamaWikipedia


If you have any questions,please feel free to contact us.We can try our best to help you.
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text:
Glloboçen (, formerly Gollomboç; Macedonian and Bulgarian: Глобочени) is a village on Lake Prespa in the Pustec Municipality located in the Korçë County in Albania.

Geography
Glloboçeni is situated on the western shore of the Greater Prespa Lake at an altitude of 879 meters (2884 feet) above sea level. The nearest settlement to the north is Dolna Gorica and to the south is Šulin.

History
The "La Macédoine et sa Population Chrétienne" survey by Dimitar Mishev (D. Brankov) from 1905 shows that the inhabitants of the village of Glubochani were in the bosom of the Patriarchate of Constantinople.

A survey by Georgi Trajchev in 1911 stated the village as having 33 houses and 319 residents.

The French linguist André Mazon, in his study on Slavic folklore in Albania from 1936, noted  Glomboč as a Bulgarian village in the region of Mala Prespa.

During World War II, 24 of the village's 40 houses were burnt down.

In 2013, the village's official name was changed back from Gollomboç to Glloboçeni.

Demographics
A 2007 estimate put the village's population at 300 to 350 people. The village is composed of ethnic Macedonians, which form part of the larger Macedonian minority in Albania.  According to Bulgarian sources, including a local one, the local inhabitants are Bulgarians.

Culture
Glloboçeni is the nearest village to the Church of the Annunciation, a rock church situated on the Lake Prespa shore at an altitude of roughly 25 meters (80 feet). It was established in the 14th century.

People from Glloboçeni
Sotir Kaleškov, member of the Internal Macedonian Revolutionary Organization
Ilinden Spasse, writer, son of Sterjo Spasse
Sterjo Spasse, writer
Gjorgi Tane, politician

References

Populated places in Pustec Municipality
Villages in Korçë County
Macedonian communities in Albania


text:
Galderma S.A. is a Swiss pharmaceutical company specializing in dermatological treatments and skin care products. Formerly a subsidiary of L'Oréal and Nestlé, it has been held by a consortium of private institutional investors since 2019.

Galderma was formed in 1981 as a joint venture between Nestlé and L'Oréal, then it became a subsidiary of Nestlé. Since 2019, it belongs to an investment fund. The company, headed by president and CEO Flemming Ørnskov (ex-Shire), has 33 sites in 100 countries with a worldwide network of distributors and employs more than 4,600 people. The headquarters is based in Zug, Switzerland. In 2021, the slogan of Galderma is "Advancing dermatology for every skin story".

History

The origins of Galderma date back to 1961 and the founding of the Owen dermatology company in Dallas, Texas, USA by M. Owen.

In 1979, Professor Hans Schaefer founded the International Center for Dermatological Research (CIRD) in Sophia Antipolis, with the support of the CEO of L'Oréal, François Dalle, who wanted to diversify his cosmetic research into the drug sector. At the same time, Nestlé, which also had ambitions in dermatology bought the Owen laboratory.

L'Oréal and Nestlé joined forces to create Galderma in 1981 (CIRD became Galderma R&D). It was a joint venture between the two companies.

In 2007, the Galderma Global Corporate Campaign won the Medical Marketing Association's International Award of Excellence.

In 2010, sales reached 1.2 billion euros, an increase of 16.1% over 2009.

Galderma expanded by specializing in the research, development and commercialization of products for dermatology (skin care) patients. It reached a significant size, with 38 subsidiaries present in 100 countries in the 2010s. It diversified into aesthetic medicine products with the botulinum toxin Azzalure, a field in which it strengthened in 2010 with the acquisition of the Swedish medical-device company Q-Med.

In 2014, Nestlé bought back all the shares from L'Oréal, thus creating a new unit of Nestlé group called Nestle Skin Health. The transaction had a value of €3.1 billion (US$4.23 billion) and was paid for by Nestlé with 21.2 million L'Oréal shares. L'Oréal paid €3.4 billion (US$4.63 billion) for the remaining 27.3 million shares.

In 2019, Nestlé sold Galderma for $10.2 billion to a consortium comprising the EQT VIII fund, Luxinva (a wholly owned subsidiary of Abu Dhabi Investment Authority), PSP Investments and other institutional investors. Since then, it has been the largest independent dermatology company in the world.

In November 2021, Galderma bought California-based Alastin, a firm specialising in specialist skincare products, for an undisclosed price.

In June 2022, Galderma announced positive results in two Phase III trials for liquid botulinum toxin A, showing RelabotulinumtoxinA significantly reduced frown line severity and was well tolerated. This result primes the company to apply for approval in the US and other global markets.

Also in June 2022, Galderma announced positive data from Phase III trial, showing efficacy and safety of nemolizumab in patients with prurigo nodularis. Nemolizumab is a monoclonal antibody that blocks the signaling of IL-31, a neuroimmune cytokine involved in the pathogenesis of prurigo nodularis.

Activities
Galderma is specialized in the research, development and commercialization of skin care products and treatments across aesthetics, consumer care and prescription medicine.

Galderma provides a range of over-the-counter and prescription dermatological products for skin care, aesthetics and treatment of conditions including acne, rosacea, psoriasis and other steroid-responsive dermatoses (SRD), onychomycosis (fungal nail infections), pigmentary disorders, skin cancer and skin aging. Galderma's activities are divided into three business units: aesthetics, consumer care and prescription medicine. Galderma's products are sold in more than 100 countries.

Aesthetics
In 2007, Galderma and Ipsen signed a licensing agreement for the distribution of the botulinum toxin Dysport, known as Azzalure in the European Union, for the improvement of glabellar lines (frown lines between the eyes). More than 40 million treatments have been performed in the United States and the European Union.

The main brands are Restylane, Azzalure, Dysport, Alluzience and Sculptra.

Consumer care
Galderma's products are available over-the-counter to consumers.

The main consumer care brands are Cetaphil, with its range of skin care products for all ages; Benzac and Differin OTC for mild-to-moderate acne; and Loceryl, used to treat fungal nail infections, and Alastin.

Prescription Medicine
Disease areas are atopic dermatitis, dermato-oncology and psoriasis.

The main brands are Aklief, Benzac, Cetaphil, Epiduo, Epiduo Forte, Loceryl, Differin, Soolantra, Mirvaso, Oracea and Metvix.

Research and development
The company invests substantially in research and development and sources new treatments from its own activities and from its partnerships with others. It divides its research and development departments between six sites:

Lausanne, Switzerland
Zug, Switzerland
Uppsala, Sweden
Dallas, Texas
Bridgewater, New Jersey
Baie d'Urfé, Canada

Production
Galderma has manufacturing facilities at the following locations:

 The Alby-sur-Chéran plant in France, inaugurated in 1994, supplies over 70 countries.
 The Baie d'Urfé (Montreal) facility in Canada started production in 2000 and supplies North America.
 The plant in Uppsala, Sweden, manufactures aesthetic and corrective products.
 The Hortolândia site in the state of São Paulo, Brazil serves South America.

Governance

 Flemming Ørnskov, chief executive officer
 Thomas Dittrich chief financial officer
 Adrian Murphy, vice president, head of global operations
 Allison Pinkham, chief human resources officer

Notes and references

See also
 List of pharmaceutical companies
 Pharmaceutical industry in Switzerland

Companies based in Lausanne
Pharmaceutical companies of Switzerland
L'Oréal
Nestlé
Skin care
Health care
Pharmaceutical companies established in 1981
Swiss companies established in 1981
2019 mergers and acquisitions


The HISTORY CAPE shows some of the milestones in 'zoeppritz since 1828's history. In this cape, woven from soft cotton, you can discover among other things the portraits of both of the company founders, the Zeppelin dating back to 1928, the historical company's site and much more. Special accents are set by the fringed edge, the soft leather strap at the back and on the inside close to the neck and the silver lurex-whipstitch on the arm and front of the big shawl collar. The sleeves can be adjusted with small push buttons. Inspiration for the HISTORY CAPE came from the blanket HISTORY. Different colors of whipstitch are available upon request.


text:
Planners' Picks — September 7, 2021
Planners' Picks
A collection of resources from CSN planning committee members worth mentioning
Students are back on campus, school is in session, and we lead ourselves and others into the fall semester. Explore these resources on team development, DEI, hybrid/remote work, and a weekly dose of personal self-leadership development.
||| Resources on Work Culture & Team Development |||
Let us, then, be up and doing
Rich Gassen published an article on Linkedin 5 years ago about participation in honor of Labor Day.
One of the greatest and simplest tools for learning more and growing more is doing more. It may or may not involve more activity. We're not talking, necessarily, about action but of involvement.
Revisit the entire short article here:
https://www.linkedin.com/pulse/let-us-up-doing-rich-gassen/
"The goal is not to be perfect by the end. The goal is to be better today." – Simon Sinek
Defining the skills citizens will need in the future world of work
To future-proof citizens' ability to work, they will require new skills—but which ones? A survey of 18,000 people in 15 countries suggests those that governments may wish to prioritize. All citizens will benefit from having a set of foundational skills that help them fulfill the following three criteria, no matter the sector in which they work or their occupation:
add value beyond what can be done by automated systems and intelligent machines
operate in a digital environment
continually adapt to new ways of working and new occupations
https://www.mckinsey.com/industries/public-and-social-sector/our-insights/defining-the-skills-citizens-will-need-in-the-future-world-of-work
In the modern economy, motivation is a tricky thing.
A hundred years ago, when people like Frederick Taylor were pioneering the field of scientific management, motivation was pretty easy. The idea was you could switch people from an hourly rate to a piece-rate system to do a set of repetitive tasks, and it would incentivize them to do the tasks faster. It was a rudimentary idea, but in some organizations, it's still the philosophy behind how pay — especially incentive pay — is set. And there's actually a decent amount of research that incentives like that can work to increase motivation when there is a really clear understanding of exactly what tasks must be done to earn the reward. But in knowledge work or creative work economy, those easy-to-understand, repetitive tasks are becoming rarer and rarer.
Fortunately, there's another option to increase motivation.
https://ideas.ted.com/3-things-that-keep-people-feeling-motivated-at-work/
||| Resources on Hybrid and Remote Work |||
Is Your Job Shifting to a Hybrid Work Plan? These Tips Can Help
Since the start of the pandemic, many nonessential workers have had to adjust to a remote work environment. This shift introduced new challenges, such as navigating virtual meetings and recreating a productive workspace from home. As the pandemic evolves, some companies are choosing to return to the office 100 percent of the time, some are adopting a fully remote policy, and others are entertaining the idea of a hybrid work model.
Unlike a fully remote organization where everyone works from home, a hybrid plan means that you might be working in the office while other key teammates are working remotely (or vice versa). Here are a few tips to maintain effective communication between workplaces.
https://www.grammarly.com/blog/hybrid-work-plan-communication-tips/
How To Host Inclusive Hybrid Meetings
Learning & Talent Development recently collaborated with the Center for User Experience, the Office of Strategic Consulting, and the Office of Compliance to create guidance on best practices for inclusive meetings with both in-person and virtual participants.
You can access the guide for information on how to set up meeting rooms, leverage existing technology, build inclusivity into meetings, and much more.
https://it.wisc.edu/learn/guides/inclusive-hybrid-meetings/
"Civility costs nothing, and buys everything." – Mary Wortley Montagu
A Compassionate Guide For Your Return to Work Plan
Author and speaker Heather Younger asks: How do we, as leaders, navigate managing two groups of people with entirely different histories this past year as they converge into one?
The best way to keep your workplace united after so much time apart is to be there for them on an organization-wide level. Reach out to each team member, each group of team members, whether united by age, race, culture, background, religion, or opinions, meet them in their shoes. Another term for this form of meeting a person where they are at is empathy.
The WFH group of employees and the non-remote folks will have vastly different experiences from the past year, but at the core, they don't differ too much. The past year has been hard and filled with change, regardless of if that change led you home or not. Stand with your team as they relive and are shaped by their past experiences daily. Comfort, advise, and care for each employee as new changes will bring about new struggles.
The empathetic actions I have described so far are incredibly important, but right there with them is the compassion component at the same level of importance. It is powerful to sit with a person in the midst of their struggles or their joys. It is another incredible thing altogether to take action to alleviate their pain or share with them in their joy.
https://employeefanatix.com/a-compassionate-guide-for-your-return-to-work-plan/
||| Resources on DEI |||
Resources at CUPA-HR around diversity and inclusion
Stories of diversity and inclusion can enrich a campus community and move the institution along the path to greater cultural understanding and competence. In these facilitator guides, you will find tools to help you use the project's portraits and videos to facilitate discussions on campus. CUPA-HR offers these materials and conversation starters for topics like microaggressions, race and ethnicity, LGBT issues, and more.
https://diversity.cupahr.org/discussions/
||| Resources on Self-Leadership Development |||
Stay Cool Under Pressure — Without Appearing Cold
If you're a manager who handles stress with ease, while your boss and team become wound ever tighter, you may give the unfortunate impression that you don't care about the work or your colleagues. Being cool under stress is an asset, but your colleagues may read your unruffled nature as "nonchalance." This perception could hurt your career trajectory. This article discusses three ways to change that perception.
https://hbr.org/2020/11/stay-cool-under-pressure-without-appearing-cold
Linkedin Learning: Leading with Emotional Intelligence
Emotions are all around us in the office, and it's important for leaders to understand how to harness them to cultivate productivity and positive relationships. In this course, Britt Andreatta shares how to boost your emotional quotient (EQ) to better lead teams, work with peers, and manage up. Learn what emotional intelligence is and how it factors in at work, and discover concrete techniques for raising your own EQ. This includes perceiving yourself accurately, exercising emotional self-control, understanding and managing your triggers, and developing empathy. Then, turn those lessons around to build your awareness of others and become a more inspiring—and effective—leader.
Analyze the brain science behind emotional intelligence.
Identify and assess your emotions.
Determine how to exercise emotional self-control.
Identify your triggers and how to respond the them.
Assess how others respond at work.
Determine how to maximize team performance using emotional intelligence.
Discover how to catalyze change.
https://www.linkedin.com/learning/leading-with-emotional-intelligence-3/lead-with-emotional-intelligence?u=56745513
Downloadable Action for Happiness September Calendar: Self-Care
Self-care isn't selfish, it's essential. No-one's perfect. But so often we compare our insides to other people's outsides. This month we're encouraging everyone to be kinder to themselves (as well as others), especially when things go wrong. Self-care increases our resilience and helps us get more out of life. It also helps us accept others as they are too.
https://www.actionforhappiness.org/september
||| Upcoming Events |||
Live Webinar: Character & Happiness – with Angela Duckworth
Thurs 9 Sept – Online via Zoom – 1:00-2:00pm CST
What is character? And how does it support wellbeing?
At this event, psychologist Angela Duckworth will share what she's learnt in her years of research into character. She'll explain how we don't need to rely on talent to be successful or to achieve goals; instead we can develop our strengths to respond wisely to whatever life sends our way.
Angela defines character as "everything we do to help other people as well as ourselves". She believes we can cultivate character strengths in three dimensions: strengths of heart (e.g. gratitude), strengths of will (e.g. grit), and strengths of mind (e.g. curiosity).
Pre-register below:
https://www.eventbrite.co.uk/e/character-happiness-with-angela-duckworth-tickets-162422908291
"The trick is in what one emphasizes. We either make ourselves miserable, or we make ourselves happy. The amount of work is the same." – Carlos Castaneda
Previous post: Planners' Picks — August 31, 2021
Next post: Planners' Picks — September 14, 2021
Planners' Picks — January 18, 2022
Planners' Picks — January 4, 2022
Planners' Picks — December 28, 2021

redpajama_set_name: RedPajamaCommonCrawl


text:
package io.opentelemetry.sdk.metrics.internal.aggregator;

import io.opentelemetry.api.common.Attributes;
import io.opentelemetry.sdk.internal.PrimitiveLongList;
import io.opentelemetry.sdk.metrics.InstrumentType;
import io.opentelemetry.sdk.metrics.data.DoublePointData;
import io.opentelemetry.sdk.metrics.data.HistogramPointData;
import io.opentelemetry.sdk.metrics.data.LongPointData;
import io.opentelemetry.sdk.metrics.internal.data.ImmutableDoublePointData;
import io.opentelemetry.sdk.metrics.internal.data.ImmutableHistogramPointData;
import io.opentelemetry.sdk.metrics.internal.data.ImmutableLongPointData;
import io.opentelemetry.sdk.metrics.internal.data.exponentialhistogram.ExponentialHistogramPointData;
import io.opentelemetry.sdk.metrics.internal.descriptor.InstrumentDescriptor;
import java.util.ArrayList;
import java.util.List;
import java.util.Map;

final class MetricDataUtils {
  private MetricDataUtils() {}

  /** Returns true if the instrument does not allow negative measurements. */
  static boolean isMonotonicInstrument(InstrumentDescriptor descriptor) {
    InstrumentType type = descriptor.getType();
    return type == InstrumentType.HISTOGRAM
        || type == InstrumentType.COUNTER
        || type == InstrumentType.OBSERVABLE_COUNTER;
  }

  static List<LongPointData> toLongPointList(
      Map<Attributes, LongAccumulation> accumulationMap, long startEpochNanos, long epochNanos) {
    List<LongPointData> points = new ArrayList<>(accumulationMap.size());
    accumulationMap.forEach(
        (labels, accumulation) ->
            points.add(
                ImmutableLongPointData.create(
                    startEpochNanos,
                    epochNanos,
                    labels,
                    accumulation.getValue(),
                    accumulation.getExemplars())));
    return points;
  }

  static List<DoublePointData> toDoublePointList(
      Map<Attributes, DoubleAccumulation> accumulationMap, long startEpochNanos, long epochNanos) {
    List<DoublePointData> points = new ArrayList<>(accumulationMap.size());
    accumulationMap.forEach(
        (labels, accumulation) ->
            points.add(
                ImmutableDoublePointData.create(
                    startEpochNanos,
                    epochNanos,
                    labels,
                    accumulation.getValue(),
                    accumulation.getExemplars())));
    return points;
  }

  static List<HistogramPointData> toExplicitBucketHistogramPointList(
      Map<Attributes, ExplicitBucketHistogramAccumulation> accumulationMap,
      long startEpochNanos,
      long epochNanos,
      List<Double> boundaries) {
    List<HistogramPointData> points = new ArrayList<>(accumulationMap.size());
    accumulationMap.forEach(
        (labels, aggregator) -> {
          List<Long> counts = PrimitiveLongList.wrap(aggregator.getCounts().clone());
          points.add(
              ImmutableHistogramPointData.create(
                  startEpochNanos,
                  epochNanos,
                  labels,
                  aggregator.getSum(),
                  aggregator.getMin(),
                  aggregator.getMax(),
                  boundaries,
                  counts,
                  aggregator.getExemplars()));
        });
    return points;
  }

  static List<ExponentialHistogramPointData> toExponentialHistogramPointList(
      Map<Attributes, ExponentialHistogramAccumulation> accumulationMap,
      long startEpochNanos,
      long epochNanos) {
    List<ExponentialHistogramPointData> points = new ArrayList<>(accumulationMap.size());
    accumulationMap.forEach(
        (attributes, aggregator) ->
            points.add(
                ExponentialHistogramPointData.create(
                    aggregator.getScale(),
                    aggregator.getSum(),
                    aggregator.getZeroCount(),
                    aggregator.getMin(),
                    aggregator.getMax(),
                    aggregator.getPositiveBuckets(),
                    aggregator.getNegativeBuckets(),
                    startEpochNanos,
                    epochNanos,
                    attributes,
                    aggregator.getExemplars())));
    return points;
  }
}

redpajama_set_name: RedPajamaGithub


Term : Lease or Rental. ▪Rate Per Annum: 3.5 Million Naira. ▪Location: Northern Foreshore Estate, Chevron Drive, Nesr Ebeano Super-Market. ▪Lovely 4 Bedroom Detached House Within a Cluster. Well Planned.
Well Built and Beautifully Finished 4 Bedroom Semi Detached Duplex.


text:
Bibliographic details for Reference:Reference-019840
Page name: Reference:Reference-019840
Author: CSDMS contributors
Publisher: CSDMS, .
Date of last revision: 6 October 2022 17:46 UTC
Permanent URL: https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425
Page Version ID: 419425
Citation styles for Reference:Reference-019840
Reference:Reference-019840. (2022, October 6). CSDMS, . Retrieved 14:53, January 30, 2023 from https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425.
"Reference:Reference-019840." CSDMS, . 6 Oct 2022, 17:46 UTC. 30 Jan 2023, 14:53 <https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425>.
CSDMS contributors, 'Reference:Reference-019840', CSDMS, , 6 October 2022, 17:46 UTC, <https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425> [accessed 30 January 2023]
CSDMS contributors, "Reference:Reference-019840," CSDMS, , https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425 (accessed January 30, 2023).
CSDMS contributors. Reference:Reference-019840 [Internet]. CSDMS, ; 2022 Oct 6, 17:46 UTC [cited 2023 Jan 30]. Available from: https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425.
Reference:Reference-019840, https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425 (last visited January 30, 2023).
author = "CSDMS",
title = "Reference:Reference-019840 --- CSDMS{,} ",
url = "https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425",
url = "\url{https://csdms.colorado.edu/csdms_wiki/index.php?title=Reference:Reference-019840&oldid=419425}",
Retrieved from "https://csdms.colorado.edu/wiki/Special:CiteThisPage"


text:
using System;
using System.Collections.Generic;
using System.Diagnostics.Contracts;
using System.Text;
using Microsoft.Extensions.Primitives;

namespace HtcSharp.HttpModule.Http.Headers {
    // SourceTools-Start
    // Remote-File C:\ASP\src\Http\Headers\src\CookieHeaderValue.cs
    // Start-At-Remote-Line 11
    // SourceTools-End
    // http://tools.ietf.org/html/rfc6265
    public class CookieHeaderValue {
        private static readonly CookieHeaderParser SingleValueParser = new CookieHeaderParser(supportsMultipleValues: false);
        private static readonly CookieHeaderParser MultipleValueParser = new CookieHeaderParser(supportsMultipleValues: true);

        private StringSegment _name;
        private StringSegment _value;

        private CookieHeaderValue() {
            // Used by the parser to create a new instance of this type.
        }

        public CookieHeaderValue(StringSegment name)
            : this(name, StringSegment.Empty) {
            if (name == null) {
                throw new ArgumentNullException(nameof(name));
            }
        }

        public CookieHeaderValue(StringSegment name, StringSegment value) {
            if (name == null) {
                throw new ArgumentNullException(nameof(name));
            }

            if (value == null) {
                throw new ArgumentNullException(nameof(value));
            }

            Name = name;
            Value = value;
        }

        public StringSegment Name {
            get { return _name; }
            set {
                CheckNameFormat(value, nameof(value));
                _name = value;
            }
        }

        public StringSegment Value {
            get { return _value; }
            set {
                CheckValueFormat(value, nameof(value));
                _value = value;
            }
        }

        // name="val ue";
        public override string ToString() {
            var header = new StringBuilder();

            header.Append(_name.AsSpan());
            header.Append("=");
            header.Append(_value.AsSpan());

            return header.ToString();
        }

        public static CookieHeaderValue Parse(StringSegment input) {
            var index = 0;
            return SingleValueParser.ParseValue(input, ref index);
        }

        public static bool TryParse(StringSegment input, out CookieHeaderValue parsedValue) {
            var index = 0;
            return SingleValueParser.TryParseValue(input, ref index, out parsedValue);
        }

        public static IList<CookieHeaderValue> ParseList(IList<string> inputs) {
            return MultipleValueParser.ParseValues(inputs);
        }

        public static IList<CookieHeaderValue> ParseStrictList(IList<string> inputs) {
            return MultipleValueParser.ParseStrictValues(inputs);
        }

        public static bool TryParseList(IList<string> inputs, out IList<CookieHeaderValue> parsedValues) {
            return MultipleValueParser.TryParseValues(inputs, out parsedValues);
        }

        public static bool TryParseStrictList(IList<string> inputs, out IList<CookieHeaderValue> parsedValues) {
            return MultipleValueParser.TryParseStrictValues(inputs, out parsedValues);
        }

        // name=value; name="value"
        internal static bool TryGetCookieLength(StringSegment input, ref int offset, out CookieHeaderValue parsedValue) {
            Contract.Requires(offset >= 0);

            parsedValue = null;

            if (StringSegment.IsNullOrEmpty(input) || (offset >= input.Length)) {
                return false;
            }

            var result = new CookieHeaderValue();

            // The caller should have already consumed any leading whitespace, commas, etc..

            // Name=value;

            // Name
            var itemLength = HttpRuleParser.GetTokenLength(input, offset);
            if (itemLength == 0) {
                return false;
            }

            result._name = input.Subsegment(offset, itemLength);
            offset += itemLength;

            // = (no spaces)
            if (!ReadEqualsSign(input, ref offset)) {
                return false;
            }

            // value or "quoted value"
            // The value may be empty
            result._value = GetCookieValue(input, ref offset);

            parsedValue = result;
            return true;
        }

        // cookie-value      = *cookie-octet / ( DQUOTE* cookie-octet DQUOTE )
        // cookie-octet      = %x21 / %x23-2B / %x2D-3A / %x3C-5B / %x5D-7E
        //                     ; US-ASCII characters excluding CTLs, whitespace DQUOTE, comma, semicolon, and backslash
        internal static StringSegment GetCookieValue(StringSegment input, ref int offset) {
            Contract.Requires(input != null);
            Contract.Requires(offset >= 0);
            Contract.Ensures((Contract.Result<int>() >= 0) && (Contract.Result<int>() <= (input.Length - offset)));

            var startIndex = offset;

            if (offset >= input.Length) {
                return StringSegment.Empty;
            }

            var inQuotes = false;

            if (input[offset] == '"') {
                inQuotes = true;
                offset++;
            }

            while (offset < input.Length) {
                var c = input[offset];
                if (!IsCookieValueChar(c)) {
                    break;
                }

                offset++;
            }

            if (inQuotes) {
                if (offset == input.Length || input[offset] != '"') {
                    // Missing final quote
                    return StringSegment.Empty;
                }

                offset++;
            }

            int length = offset - startIndex;
            if (offset > startIndex) {
                return input.Subsegment(startIndex, length);
            }

            return StringSegment.Empty;
        }

        private static bool ReadEqualsSign(StringSegment input, ref int offset) {
            // = (no spaces)
            if (offset >= input.Length || input[offset] != '=') {
                return false;
            }

            offset++;
            return true;
        }

        // cookie-octet      = %x21 / %x23-2B / %x2D-3A / %x3C-5B / %x5D-7E
        //                     ; US-ASCII characters excluding CTLs, whitespace DQUOTE, comma, semicolon, and backslash
        private static bool IsCookieValueChar(char c) {
            if (c < 0x21 || c > 0x7E) {
                return false;
            }

            return !(c == '"' || c == ',' || c == ';' || c == '\\');
        }

        internal static void CheckNameFormat(StringSegment name, string parameterName) {
            if (name == null) {
                throw new ArgumentNullException(nameof(name));
            }

            if (HttpRuleParser.GetTokenLength(name, 0) != name.Length) {
                throw new ArgumentException("Invalid cookie name: " + name, parameterName);
            }
        }

        internal static void CheckValueFormat(StringSegment value, string parameterName) {
            if (value == null) {
                throw new ArgumentNullException(nameof(value));
            }

            var offset = 0;
            var result = GetCookieValue(value, ref offset);
            if (result.Length != value.Length) {
                throw new ArgumentException("Invalid cookie value: " + value, parameterName);
            }
        }

        public override bool Equals(object obj) {
            var other = obj as CookieHeaderValue;

            if (other == null) {
                return false;
            }

            return StringSegment.Equals(_name, other._name, StringComparison.OrdinalIgnoreCase)
                   && StringSegment.Equals(_value, other._value, StringComparison.OrdinalIgnoreCase);
        }

        public override int GetHashCode() {
            return _name.GetHashCode() ^ _value.GetHashCode();
        }
    }
}


text:
Work in Slow Motion
Years ago, a mentor told me a story about NFL quarterback Joe Montana. He wasn't the fastest guy on the field and didn't have the strongest arm, but he saw the field in slow motion. It was his unfair advantage.
This mentor explained this as I was struggling to pick up new skills and feeling overwhelmed by all the work on my plate. "Prioritize the important stuff," he said. "And everything else will slow down."
I've never forgotten that advice and think about it often. When you strip away the busy work, our careers aren't nearly as complicated as we make them seem. The most successful people know how to do the work that pays the bills.
Here's an old ESPN clip about Montana that sums up what it was like to play with him:
Montana was neither exceptionally fast nor tall nor did he have a bazooka for an arm. The man whom his high school quarterbacks coach said "was born to be a quarterback" won by wits and grace, style and reaction. It was if he saw the game in slow motion. Whether it was with Notre Dame or the 49ers, whether the game was played in an ice storm in Dallas or in the humidity of Miami, Montana was The Man in the fourth quarter.
"There have been, and will be, much better arms and legs and much better bodies on quarterbacks in the NFL," said former 49er teammate Randy Cross, "but if you have to win a game or score a touchdown or win a championship, the only guy to get is Joe Montana."
I love this anecdote. It's exactly the kind of person I aspire to be in my career. It describes the kind of people I enjoy working with. And it's the inspiration I want to share with others. Strip away all the trivial stuff and everything else will slow down.
More in Essays
Google and the Future of B2B Content Marketing
The True North Formula
6 Jul 2017 – 2 min read
Why Email Marketing Is a Missed Opportunity for Agencies
"Playing it safe is the riskiest course of all."
Hey all, Here are a few things I've been writing and pondering lately. Enjoy this week's issue and if you're feeling inspired, pass it on. 1. Work in Slow Motion Busy work is stressful. Meaningful work is satisfying. There will be more distractions than
Jimmy Daly 22 Dec 2016 • 2 min read
I saw this the other day in a job description and it really depressed me. I won't call out the company—I'm sure there's some legalese that requires them to include this. Still, this is more aptly named "health risks" than


text:
Q: HLS inequality not suitable to bound this integral I am trying to bound the following integral for $f \in L^{n/2}(\mathbb{R}^n)$:
$\int_{\mathbb{R}^n}\int_{\mathbb{R}^n} f(x) \lvert x-y \lvert^{2(2-n)}f(y)dxdy$. Because of the factor 2 in the exponent, the condition $0<\lambda<n$ in the Hardy-Littlewood-Sobolev inequality fails for $\lambda=2n-4$ and $n>3$. Is there another way to bound this integral?

A: I'm probably missing something, but how about this: Suppose $0<f$ is continuous (don't even worry about integrability for now). Fix $x\in \mathbb{R}^n$ and let $r>0$ be such that $f(y)>f(x)/2>0 $ for every $y\in B:=B_\delta(x)$. Then use polar coordinates to write
\begin{equation}
\begin{split}
\int_{\mathbb{R}^n} |x-y|^{-\alpha} f(y)\, dy & \geq \dfrac{f(x)}{2}\int_B |x-y|^{-\alpha}\, dy\\
& = \dfrac{f(x)}{2} \int_{B_\delta(0)} |y|^{-\alpha}\, dy.
\end{split}
\end{equation}
So if $\alpha>n$ (as is the case for you if $n>3$), then the first integral is $\infty$ for any $x$, so the whole integral is infinite in this case.

redpajama_set_name: RedPajamaStackExchange


text:
Q: Pandas from Django .last() query I can not create a dataframe when using only a single row - in this case using the .last() record for all the users.
I am trying to get the very last row information.
for i in a:

    qs = Cash.objects.filter ( id = i.id ).order_by ( 'month' ).last()

    df = pd.DataFrame.from_records ( qs )

or something like
    df = read_frame ( qs )

I get the following error:
object of type 'Cash' has no len()

Thank you very much.

A: You can use slicing to limit queryset with one record:
qs = Cash.objects.filter ( id = i.id ).order_by ( '-month' )[:1]

df = pd.DataFrame.from_records ( qs )

Note that negative indexing is not supported.


It is becoming increasingly apparent that microglia, the immune cells of the CNS, and their peripheral counterparts, macrophages, have a major role in normal physiology and pathology. Recent technological advances in the production of particular cell types from induced pluripotent stem cells have led to an interest in applying this methodology to the production of microglia. Here, we discuss recent advances in this area and describe how they will aid our future understanding of microglia.
Wolf, S. A. Boddeke, H. W. & Kettenmann, H. Microglia in physiology and disease. Annu. Rev. Physiol. 10, 619–643 (2017).
Amor, S. et al. Inflammation in neurodegenerative diseases – an update. Immunology 142, 151–166 (2014).
Brazelton, T. R. Rossi, F. M. Keshet, G. I. & Blau, H. M. From marrow to brain: expression of neuronal phenotypes in adult mice. Science 290, 1775–1779 (2000).
Waisman, A. Ginhoux, F. Greter, M. Bruttger, J. Homeostasis of microglia in the adult brain: review of novel microglia depletion systems. Trends Immunol. 36, 625–636 (2015).
Karch, C. M. & Goate, A. M. Alzheimer's disease risk genes and mechanisms of disease pathogenesis. Biol. Psychiatry 77, 43–51 (2015).
Villegas-Llerena, C. et al. Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease. Curr. Opin. Neurobiol. 36, 74–81 (2016).
Gonsette, R. E. Neurodegeneration in multiple sclerosis: the role of oxidative stress and excitotoxicity. J. Neurol. Sci. 274, 48–53 (2008).
Tansey, M. G. & Goldberg, M. S. Neuroinflammation in Parkinson's disease; its role in neuronal death and implications for therapeutic intervention. Neurobiol. Dis. 37, 510–518 (2010).
Crotti, A. & Glass, C. K. The choreography of neuroinflammation in Huntington's disease. Trends Immunol. 36, 364–373 (2015).
Morello, G. Spampinato, A. G. Cavallaro, S. Neuroinflammation and ALS: transcriptomic insights into molecular disease mechanisms and therapeutic targets. Mediators Inflamm. https://doi.org/10.1155/2017/7070469 (2017).
Sha nks, N. Greek, R. Greek, J. Are animal models predictive for humans? Philos. Ethics Humanit. Med. 4, 2 (2009).
Keene, C. D. et al. Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines. Pathobiol. Aging Age Relat. Dis. 6, 32397 (2016).
Swami, V., Furnham, A. & Christopher, A. N. Free the animals? Investigating attitudes toward animal testing in Britain and the United States. Scand. J. Psychol. 49, 269–276 (2008).
Ohgidani, M. et al. Direct induction of ramified microglia-like cells from human monocytes: dynamic microglial dysfunction in Nasu-Hakola disease. Sci. Rep. 4, 4957 (2014).
Ryan, K. J. et al. A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants. Sci. Trans. Med. 20, 421 (2017).
Sturgeon, C. M. et al. Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells. Nat. Biotechnol. 32, 554–561 (2014).
Arber, C. Lovejoy, C. Wray, S. Stem cell models of Alzheimer's disease: progress and challenges. Alzheimers Res. Ther. 9, 42–59 (2017).
Kierdorf, K. Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat. Neurosci. 16, 273–280 (2013).
Davies, L. C. & Taylor, P. R. Tissue-resident macrophages: then and now. Immunology 144, 541–548 (2015).
Hoeffel, G. et al. C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages. Immunity 42, 665–678 (2015).
Buchrieser, J. James, W. Moore, M. D. Human induced pluripotent stem cell-derived macrophages share ontogeny with MYB-independent tissue-resident macrophages. Stem Cell Rep. 8, 334–345 (2017).
Muffat, J. et al. Efficient derivation of microglia-like cells from human pluripotent stem cells. Nat. Med. 22, 1358–1367 (2016).
Douvaras, P. et al. Directed Differentiation of Human Pluripotent Stem Cells to Microglia. Stem Cell Rep. 8, 1516–1524 (2017).
Pandya, H. et al. Differentiation of human and murine induced pluripotent stem cells to microglia-like cells. Nat. Neurosci. 20, 753–759 (2017).
Abud, E. et al. iPSC-derived human microglia-like cells to study neurological diseases. Neuron 94, 278–293 (2017).
Haenseler, W. et al. A highly efficient human pluripotent stem cell microglia model displays a neuronal-co-culture-specific expression profile and inflammatory response. Stem Cell Rep. 8, 1727–1742 (2017).
Takata, K. et al. Induced-pluripotent-stem-cell-derived primitive macrophages provide a platform for modeling tissue-resident macrophage differentiation and function. Immunity 47, 183–198 (2017).
Karlsson, K. R. Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3. Exp. Hematol. 36, 1167–1175 (2008).
Lachmann, N. et al. Large-scale haematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies. Stem Cell Rep. 4, 282–296 (2015).
Murray, P. J. et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 41, 14–20 (2014).
Moore, C. S. et al. P2Y12 expression and function in alternatively activated human microglia. Neurol. Neuroimmunol. Neuroinflamm. 2, e80 (2015).
Pocock, J. M. & Kettenmann, H. Neurotransmitter receptors on microglia. Trends Neurosci. 30, 527–535 (2007).
Domercq, M. Vázquez-Villoldo, N. Matute, C. Neurotransmitter signaling in the pathophysiology of microglia. Front. Cell Neurosci. 7, 49 (2013).
Greter, M. Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia. Immunity 37, 1050–1060 (2012).
Gosselin, D. An environment-dependent transcriptional network specifies human microglia identity. Science 356, eaal3222 (2017).
Stevens, B. et al. The classical complement cascade mediates CNS synapse elimination. Cell 131, 1164–1178 (2007).
Sousa, C. Biber, K. & Michelucci, A. Cellular and molecular characterization of microglia: a unique immune cell population. Front. Immunol. 8, 198 (2017).
Perry, V. H. Cunningham, C. Holmes, C. Systemic infections and inflammation affect chronic neurodegeneration. Nat. Rev. Immunol. 7, 161–167 (2007).
Morris, J. K. et al. Is Alzheimer's disease a systemic disease? Biochim. Biophys. Acta. 1842, 1340–1349 (2014).
Yamasaki, R. et al. Differential roles of microglia and monocytes in the inflamed central nervous system. J. Exp. Med. 211, 1533–1549 (2014).
Hooper, C. et al. Differential effects of albumin on microglia and macrophages: implications for neurodegeneration following blood-brain barrier damage. J. Neurochem. 109, 694–705 (2009).
Nimmerjahn, A. Kirchhoff, F. & Helmchen, F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308, 1314–1318 (2005).
Vogel, D. Y. et al. Human macrophage polarization in vitro: maturation and activation methods compared. Immunobiology 219, 695–703 (2014).
Suzuki, H. et al. Glycolytic pathway affects differentiation of human monocytes to regulatory macrophages. Immunol. Lett. 176, 18–27 (2016).
Mucci, A. et al. Murine iPSC-derived macrophages as a tool for disease modelling of hereditary pulmonary alveolar proteinosis due to Csf2rb deficiency. Stem Cell Rep. 7, 292–305 (2016).
Biber, K. Möller, T. Boddeke, E. Prinz, M. Central nervous system myeloid cells as drug targets: current status and translational challenges. Nat. Rev. Drug Discov. 15, 110–124 (2016).
Chen, S. K. et al. Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Cell 141, 775–785 (2010).
Biju, K. C. et al. Bone-marrow-derived microglia-based neurturin delivery protects against dopaminergic neurodegeneration in a mouse model of Parkinson's disease. Neurosci. Lett. 535, 24–29 (2013).
Conde, J. R. & Streit, W. J. Microglia in the aging brain. J. Neuropathol. Exp. Neurol. 65, 199–203 (2006).
Angelov, D. N. et al. Temporospatial relationships between macroglia and microglia during in vitro differentiation of murine stem cells. Dev. Neurosci 20, 42–51 (1998).
Tsuchiya, T. et al. Characterization of microglia induced from mouse embryonic stem cells and their migration into the brain parenchyma. J. Neuroimmunol. 160, 210–218 (2005).
Napoli, I. Kierdorf, K. Neumann, H. Microglial precursors derived from mouse embryonic stem cells. Glia 57, 1660–1671 (2009).
Beutner, C. Roy, K. Linnartz, B. Napoli, I. Neumann, H. Generation of microglial cells from mouse embryonic stem cells. Nat. Protoc. 5, 1481–1494 (2010).
van Wilgenburg, B. Browne, C. Vowles, J. Cowley, S. A. Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions. PLoS ONE 8, e71098 (2013).
J.M.P. made a substantial contribution to discussions of the content of the article. J.M.P. and T.M.P. researched data for the article, wrote the article and reviewed and/or edited the manuscript before submission.
Correspondence to Jennifer M. Pocock or Thomas M. Piers.


I am Stephanie Mayberry and I am a Christian Aspie.
This means that I am a Christian and I have Asperger's Syndrome. I hope that through this blog I can help people come to know Jesus while also gaining a better understanding of the Aspie mind.
For more resources and information, please visit my website The Christian Aspie.
I have moved to this service.
Hi I'm Jenny and I'm a Christian with Asperger's. I love your blog it voices exactly how I feel about many things. I love where you said people with autism don't need to be cured but accepted and I agree. I'll be following your blog. Here is a link to my blog http://theworldofmismatchedsocks.blogspot.com/ please read it and let me know what you think. GOD bless you.


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This events calendar is an announcement service by CoNGO to its member organizations, its NGO substantive committees, the wider civil society community, and the UN System. All events included here, including their accuracy, are the sole responsibility of their organizers. Unless explicitly indicated, inclusion of an event in this calendar does not constitute CoNGO endorsement of the event. If you have an event or meeting you want to be considered for announcement here, please email us at infonews@ngocongo.org.
Language and Migration: Experience and Memory
19 April 2021 - 1 May 2021
« Strengthening the prevention and treatment of cannabis problematic use
Chinese Language Day »
Language and Migration: Experience and Memory Symposium
This interdisciplinary symposium will convene humanists and social scientists, field-workers and policy-makers, artists and writers, to think together about migrants as resourceful users, interpreters, and creators of language.
Language is a vital, but underexplored, factor in the lives of migrants, immigrants and refugees. It has a direct impact on the experiences and choices of individuals displaced by war, terror, or natural disasters and the decisions made by agents who provide (or fail to provide) relief, services, and status. Distilled through memory, it shapes the fictions, poems, memoirs, films and song lyrics in which migrants render loss and displacement, integration and discovery, the translation of history and culture, and the trials of identity.
The symposium will take place online between Monday, April 19 and Saturday May 1, 2021.
Special events: Our symposium will feature two keynote speakers: Prof. Sarah Dryden-Peterson of the Harvard Graduate School of Education, who will open our exchange with a lecture on Monday April 19; and Prof. Viet Thanh Nguyen, Aerol Arnold Professor of English, University of Southern California, and winner of the Pulitzer Prize for The Sympathizer, who will close the proceedings with a lecture on Saturday, May 1. On Friday evening, April 30, we are delighted to host a reading by Jhumpa Lahiri, Yiyun Li and Aleksandar Hemon, three distinguished members of Princeton's Creative Writing faculty.
The symposium program can be found here.
Registration information can be found here. There will be one zoom link for the entire conference. (Panelists and chairs will also receive a special link for their sessions.)
Our primary sponsors are the Migration Lab of the Princeton Institute for International and Regional Studies, and the Study Group for Language and the United Nations. We'd like to acknowledge additional support from the Center for Applied Linguistics, the Esperantic Studies Foundation, the Centre for Research and Documentation on World Language Problems, and Birkbeck, University of London. At Princeton, generous support has also come from the Lewis Center, the Humanities Council, the Department of English, the Department of Comparative Literature, The Department of African-American Studies, and the University Center for Human Values.
Please direct questions to Sam Evans at same@princeton.edu
CoNGO Notes: CoNGO is currently in the process of constituting an NGO Committee on Language and Languages and is calling for endorsement of the creation of this important committee. For information on this new committee, visit here. For more information on the NGO Committee on Migration, please visit ngo-migration.org. For more information on the NGO Committee on Education, Learning, and Literacy, please visit facebook.com/NGOCELLatUN.
CoNGO Recommended Events, CSO event
climate emergency, climate refugees, communication, Conference of NGOs, culture, data, digital divide, education, ESD, Harvard, history, human rights, identity, IDPs, internal displacement, interpretation, language, literacy, memory, mental health, migration, nature-based solutions, poetry, Princeton, science, social development, social protections, social science, speech, stakeholder engagement, terror, war
https://migration.princeton.edu/symposium
Princeton Institute for International and Regional Studies
infonews@ngocongo.org


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Testimonial Archives
Our law firm has successfully handled thousands of criminal, DWI, and municipal court charges throughout Burlington County and New Jersey.
DWI/DUI
THEFT & FRAUD Charges
Mount Laurel Man Charged With Vehicular Homicide and Assault By Auto
This week, the Burlington County Prosecutor's Office announced that they had filed charges for Vehicular Homicide, Assault By Auto and Driving While Intoxicated against a Mount Laurel man who had been involved in an accident in January that caused the death of one of his children and serious injuries to other.
According to reports, Ossie Thomas, 27, was allegedly operating his vehicle at speeds above the posted limit while driving through Willingboro, New Jersey. Due to Mr. Thomas' rate of speed, it is believed that he was unable to navigate a turn properly and subsequently crashed the vehicle. It is further alleged that Mr. Thomas' children were not properly restrained int he vehicle at the time of the accident.
Originally, Mr. Thomas was released after the accident. However, after the police and prosecutor's office conducted an investigation, a Warrant for the new charges was issued and Mr. Thomas was detained pending his appearance before the Burlington County Superior Court. The prosecutor's office said the decision to charge Thomas with vehicular homicide was based on eyewitness accounts and the results of toxicology tests performed after the crash.
What Charges Were Filed?
Mr. Thomas is facing multiple charges, some of which carry mandatory periods of incarceration. Specifically, he is facing charges for vehicular homicide, assault by auto, causing a fatal accident while driving with a suspended license, causing bodily injury while driving with a suspended license, two counts of endangering the welfare of a child and driving while intoxicated.
Mount Laurel DWI Attorneys
Proetta, Oliver & Fay is a Criminal Defense Law Firm in Burlington County. If you or a loved one are facing criminal or traffic charges involving Driving While Intoxicated, please do not hesitate to contact our office today at (609) 850-8284.
Our phones are answered 24 hours a day. We are available weekdays during business hours. We also meet with clients on evenings and weekends by request. We have four office locations conveniently located in Jersey City, Edison, Middletown, Cranford, Burlington, and Hamilton. All major credit cards are accepted.
525 Highway 73,
Suite 104, Marlton,
100 Horizon Center
Boulevard, Hamilton,
New Jersey, 08691
Point Pleasant Office
3828 River Road,
Suite A, Point Pleasant,
Middletown Office
180 Kings Highway,
Middletown Township,
For a Free Consultation Call: 609-850-8284 Office visits are by appointment only
© 2018 Proetta, Oliver & Fay


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Thermally activated, single component epoxy systems
Unruh, David A.
Pastine, Stefan J.
Moreton, Jessica C.
Frechet, Jean
Chemical Science Program
Office of the VP
A single component epoxy system in which the resin and hardener components found in many two-component epoxies are combined onto the same molecule is described. The single molecule precursor to the epoxy resin contains both multiple epoxide moieties and a diamine held latent by thermally degradable carbamate linkages. These bis-carbamate "single molecule epoxies" have an essentially infinite shelf life and access a significant range in curing temperatures related to the structure of the carbamate linkages used. © 2011 American Chemical Society.
Unruh, D. A., Pastine, S. J., Moreton, J. C., & Fréchet, J. M. J. (2011). Thermally Activated, Single Component Epoxy Systems. Macromolecules, 44(16), 6318–6325. doi:10.1021/ma200673v
Synthesis of the new materials and their characterization was supported by the Director, Office of Science, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231; additional support by the Frechet Various Donors Gift Funds is also acknowledged.
American Chemical Society (ACS)
10.1021/ma200673v
Articles; Physical Science and Engineering (PSE) Division; Chemical Science Program


According to a statement by China's Center for Disease Control and Prevention, the research center in Beijing "will not only greatly enhance China's ability to monitor and prevent flu from spreading, but also increase China's influence and power in decision-making in the area" (Gale, 11/17).
"'The stockpile will be channelled to the Asian countries that need it most, as decided by the World Health Organisation,' Naoko Noda, adviser to the Japan International Cooperation System, told Reuters on the sidelines of an Asia-Europe Foundation pandemic preparedness seminar" (Ahmad, 11/17).
On Monday, Sens. Joe Lieberman (I-Conn.) and Susan Collins (R-Maine), with the Senate Homeland Security and Governmental Affairs Committee, sent a letter to HHS Secretary Kathleen Seblelius ahead of the agency's scheduled testimony before their committee today, expressing "dissatisfaction with the Obama administration's effort to distribute the H1N1 vaccine," The Hill writes. The senators believe a vaccine shortage in the U.S. was due, in part, to the "agency's decision to identify an initial target group that comprised nearly 50 percent of the U.S. population," the news service writes (Fabian, 11/16).
Reuters reports that Lieberman and Collins "praised the Health and Human Services Department for working quickly, but said the agency had sent a mixed message to the public. 'The glaring discrepancy between the demand for and supply of H1N1 vaccine in our country has resulted in pregnant women standing in line for hours, only to find no vaccine at the end,' they wrote to" Sebelius (Fox, 11/16).
"Lieberman and Collins said that a letter Sebelius penned to their panel last month about the shortage was 'a sure sign that lessons have not been learned to ensure that this situation does not happen again' because it did not admit any missteps on behalf of the federal government," The Hill reports (11/16).


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ACL Tear
Bicep Tear
Dislocated Shoulder
Sports Medicine & Arthroscopic Surgery
Office Appointments
Domestic & International Travelers
Manhattan Orthopedics Contents Specialties Diagnostic Imaging
At Manhattan Orthopedics, we are dedicated to providing our professional athletes and our weekend warriors alike, with the most advanced medical technology, the highest levels of surgical expertise, and the best medical care in Manhattan. With our available diagnostic imaging services, we are able to do just that!
We are proud to offer our patients this cutting-edge technology to help improve treatment outcomes. Ultrasound uses sound waves to visualize soft tissue such as muscles and tendons.
Ultrasonography uses a probe containing one or more acoustic transducers to send pulses of sound into the patient. Whenever a sound wave encounters a material with a different density, part of the sound wave is reflected back to the probe and is detected as an echo.
By performing ultrasound-guided procedures and exams in the office physicians can decrease time to diagnosis and care, increase the accuracy of injections, and minimize the use of ionizing radiation inpatient evaluation.
DIAGNOSTIC RADIOGRAPHY (X-RAY)
Manhattan Orthopedics offers a state of the art radiology suite, identical to those found in Citi Field (home of the NY Mets), and in Barclays Center (home of the Brooklyn Nets).
Our x-ray facility features advanced digital technology that creates significantly increased image quality, allowing for sharper x-rays, better image detail and ultimately, better visualization and interpretation of fractures and other maladies. But best of all, the equipment features an integrated generator and cesium digital detector which allows us to deliver x-ray care with a fraction of the x-ray exposure of other, older x-ray facilities.
DIAGNOSTIC FLUOROSCOPY
For any unexplained joint pain, your physician may recommend a diagnostic procedure called a fluoroscopy. This is a procedure involving multiple x-rays of a joint using a fluoroscope, which immediately shows an x-ray image. An iodine solution is injected into the joint area to highlight areas around the painful joint and bring into focus the internal workings of specific joints and soft tissue structures. Problems with the ligaments, cartilage, tendons, or the joint capsule of the hip, shoulder, knee, ankle or wrist can be identified in many cases, but the most commonly studied joints are the knee and shoulder.
This technology is very helpful to surgeons when performing surgical procedures. Interventional fluoroscopy has tremendous advantages over invasive surgical procedures because it requires a very small incision which substantially reduces recovery time and reduces the risk of infection for the patient.
Labrum Tear
Myelopathy
Rotator Cuff Surgery
Synvisc Injection
57 West 57th Street 15th Floor, New York, NY 10019
27-31 Crescent Street Apartment 3R, Astoria, NY 11102
Manhattan Orthopedics, New York, NY
Address: 57 West 57th Street, 15th Floor, New York, NY 10019
Manhattan Orthopedics, Astoria, NY
Address: 27-31 Crescent Street, Apartment 3R, Astoria, NY 11102


Airbnb and Tesla Motors are "giving travelers a new way to get away." Last week, the companies announced a partnership that will bring charging stations to select homes across the globe, starting with the California coast. "Together, we're building a world with no limits to how far you can travel and how you get there," says Airbnb. "From remote deserts to lush forests, we're unlocking highways, backroads, adventures and unique homes."
Sounds great, but how does it work? Airbnb hosts that are interested in adding a Tesla charger to their home can apply to have a charger installed in their home. To qualify for the initial phase, hosts must live in California, have five verified bookings and a rating of higher than four stars. If you are selected by Tesla, they will cover the cost of the charger but you have to cover the cost of the installation. Then, Airbnb will list you as a "Tesla-ready property" on their site, so Tesla drivers know that they can charge up while they stay with you. It only take a few hours for Tesla's Model S to charge to its full 270-mile range.
The partnership is all part of Tesla's efforts to expand charging stations for its electric vehicles to combat "range anxiety," the fear among drivers that electric vehicles can't go far enough between charges. Charging stations will be installed at a minimum of 100 Airbnb properties, including 30 high-end ones, during the first phase. To date, Tesla has a total of 499 Supercharger Stations and 2,810 Superchargers worldwide, along with several destination chargers and home plug-in chargers.


This year still shows no sign of calming down for my husband and I, but things are looking a lot brighter. After I put up my most recent post about Steve's health and ongoing issues with the welfare system, in which I imparted the news we'd been told about having to wait a year for a new DLA tribunal, our objection to the first tribunal was allowed and we got a new one without having to wait after all.
So, we had a new DLA tribunal and a new ESA tribunal within a few weeks, and thankfully, thankfully (I cannot impress that word strongly enough!), we won them both. Steve also had some follow-up tests with neurology, and things are actually moving forward! Relief upon relief!!
Steve and I have been wanting to bring a new addition into our family for good, long time. And, now that things are sorted, I can happily impart even more good news: we have adopted a cat!
Sox Herron* is settling in well, and we love her.
*For those confused about the Herron surname: it is my married name. I write under McKee as it is my maiden name.
Delighted to read your good news Ellie. I look forward to reading how Sox assumes control of the Herron household and her people servants.


We offer a range of indoor sites offering complete flexibility for a variety of events, including sales promotions, road shows, new product launches, sampling events, prize draws, data capture, workshops and demonstrations.
Standard mall display areas range from 2m x 1m to 4m x 4m, with further opportunities for external events in our 2,500 space car park.
Gyle is the ideal venue to reach over 200,000 potential customers every week. Let our marketing team help you to make the most out of the wide variety of promotions opportunities that Gyle boasts.
For further information on Promotional and Exhibition opportunities please contact Elizabeth Wood.
We have produced a Promotional Site Plan for you to download. It shows key sites within Gyle Shopping Centre that are ideal for sales promotions, data capture, road shows, sampling events and product launches.
Gyle Corporate Gift Cards are exclusive to Gyle Shopping Centre and are ideal for rewarding your staff or saying 'thank you' to clients. The same size as a credit or debit card, they can be loaded up with any amount you like from £5 to £500.
Please email Elizabeth Wood ([email protected]) with your requirements and we will contact you with payment details and to confirm your order.
High Value Card transaction £2,001 to £9,999 requests.
High Value Card transaction £10,000 and over requests.
Anti Money-Laundering (AML) Requirements (UK).
If you want more general information, please visit our Gift Cards page or get in touch with the Gyle Management team.


Here are a few pieces from the Interwebs I found interesting. Maybe you will also….
Dine and Dash 101. There are two kinds of truffles. My favorite is made of chocolate and is a reasonably priced treat. The other is for those with a more talented palate and deeper pockets that I have. Truffle hunting is tedious business and truffles are extraordinarily expensive, as a diner at a Manhattan restaurant discovered when he ordered the pasta lunch special without inquiring about the price, which turned out to be $275. His story made the New York Times last month, and the ContractsProf Blog posted a quick lesson on the application of Article 2 of the Uniform Commercial Code to the situation.
Will You Be My Valentine? Valentine's Day was last week and docracy.com put together a clever product to promote its on-line contracting service — a binding Valentine contract. Ah, contracts can be such fun!


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Whenever Will Private Investigators Dartford Begin Investigations Within Long Reach?
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The methods as well as strategies Private Investigators Dartford utilizes are the newest on the market and are certain to provide solutions. Private Investigators Dartford can assist you to provide an experienced as well as expert and comprehensive support for everybody's situation within Long Reach.
Somebody may have stolen your money within Stone, however, you could possibly get this back again. Private Investigators Dartford continues to be very discreet as well as retains a person secure throughout the actual investigation if they are accumulating cash.
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Movie stars invited for your child' college occasion in New Town can use unique personal security to help keep issues under control. You need to make sure they are secured with the aid of the VIP security while they're in the college.


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Catalogue Search for "subject:(Performing arts Great Britain... Electronic resource Main Catalogue
Starting drama teaching
By Fleming, Michael P
3rd ed
This edition is about the theory and - especially - the practice of drama teaching in primary and secondary schools. Each chapter beings with practical...
Dickens and popular entertainment
By Schlicke, Paul
Published London: Unwin Hyman, 2002
Dickens and Popular Entertainmentis the first extended study of this vital aspect of Dicken's life and work. Ranging widely through showmen's memoirs,...
Social class and television drama in contemporary Britain
This collection is a wide-ranging exploration of contemporary British television drama and its representations of social class. Through early studio-set...
British theatre since the war
By Shellard, Dominic
Published New Haven: Yale University Press, 1999
Using previously unseen material that includes the Kenneth Tynan archives, Dominic Shellard has written a comprehensive account of the British theatre...
Beswick, Katie (1)
Bourne, Stephen, 1957 October 31- (1)
Daboo, Jerri, 1967- (1)
Finburgh, Clare (1)
Fleming, Michael P (1)
Electronic books (30)
United Kingdom, Great Britain (15)
Theatre studies (12)
From 1999 2000 2002 2003 2007 2009 2011 2013 2014 2015 2017 2018 2019 2020 To 1999 2000 2002 2003 2007 2009 2011 2013 2014 2015 2017 2018 2019 2020


text:
Q: Como fazer um ComboBox com GridView? Estou tentando fazer um ComboBox que ai clicar seja preenchido com uma GridView, sei que é do DevExpress, hoje utilizo a versão 16.1.
exemplo:

A: Chama-se GridLookUpEdit.

Pode-se encapsular um gridview em um combobox.


I have no idea when I'll ever get personal online time again guys. I'm writing this today at my internship because I probably won't be on Monday, and God forbid I even attempt to plan some Saturday online time. I am so frustrated right now. Add on to that some serious sleep issues and I'm a wreck right now. I have more energy today than I thought I would considering I woke up at midnight and couldn't get back to sleep until probably 4 in the morning. *sighs* I'm just done right now.
Hope you guys have a safe weekend.
P.S: Keep reporting Travis. I noticed he's ignored an attempt for me to reason with him, so it's done–I'm going to report EVERYTHING, his script formatted stories included. I want the perverted stories gone too, but he's pushed too many of my buttons and I'm already super fed up with this who ***damn planet, so yeah, report it all. By my calculations everything from "The Huge Election" down is script formatted aside from a few pieces, so please send in reports if you have the time. And thanks to anyone sending emails. The more people who send them the more likely the admins are to see it, so keep going. We've got to get this guy so we can get our fandom back…and clean up a few others in the process.
I spent all day yesterday sitting at the hospital with my father without any electronic devices period when I was there. Needless to say, I'll attempt to get online Saturday. I'm currently at my internship and I refuse to check my personal messages while I'm here. I just wanted to let you guys know what was up with me real quick.
To anyone helping with the Travis situation, keep up the fight guys. I think we can get him if we just keep pushing. Send reports whenever you can, on both his inappropriate stories and his script formatting nightmares from years back. Every report counts, so keep up the good work.


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« Owls Advance To Semifinals | Main | Aquatic Owls Represent Well In Nashville »
Wrestling Owls Finish Solid Season
Wrestling at MUS has been a growing program for many years now, and this season was no different.
Over the President's Day weekend, the varsity wrestlers traveled to Chattanooga to compete in the State Individual Championships. This tournament gave the Owls an opportunity to focus on their individual efforts and to produce some notable finishes from West Tennessee.
MUS had four wrestlers place in their weight divisions.
Senior Andrew Gordon (275 lbs) earned a sixth-place finish after having triumphed in three matches in the heavyweight division. Freshman Barret Folk (103) had an emphatic 12-1 victory over an Ensworth opponent to give him a fifth-place finish. Junior Zach Gordon (171) won three matches before losing to an MBA opponent, 9-3, in his final match that gave him fourth place. Finally, senior Mason George (189) beat an opponent from Brentwood Academy and one from Briarcrest, advancing him to the semifinals. George then lost to a formidable McCallie opponent before winning his third-place match, 13-6.
Coach Shaun Gehres said of George, his team's highest placing wrestler, "he worked for his third-place finish as hard as most guys work that get first place."
Aside from the four Owls who placed, Andrew Maroda (119), Cameron Ridgway (135), William McGehee (145), and Sam Goldstein (152) all earned wins during the tournament.
This season began in December for the Owls with the annual Blackhorse Invitational at Houston High School. The Owls had three wrestlers who placed in the top eight as they gained valuable experience. The Owls then picked up their first wins of the regular season over Munford and White Station. After these wins, MUS sent the JV team to Nashville where four wrestlers placed fourth or better in the McGavock Invitational.
The Owls started out 2006 with an eighth-place finish in the Ravenwood Tournament, with a first and second-place individual performance by George and Andrew Gordon, respectively. The next tournament was in mid-January when MUS took on a competitive field in the CBHS Duals and came out with a fifth-place finish. Then, in local competition, MUS had earned three more team victories before the Regional tournament began.
At the Regional Championships, MUS beat Harding, 43-33, to secure a sixth straight runner-up finish in their region. After having qualified for State, the Owls traveled to Clarksville to compete in the State Duals. MUS faced two tough opponents and claimed seventh place overall.
This season has once again been satisfactory for the coaches and wrestlers. Coach Gehres, Coach Hendrix, and Coach Knaff believe that the wrestlers have once again improved and made the best of their abilities.
"I really think that the good season we had was made possible by the great senior leadership we have," said Coach Gehres, reflecting on the season.
Coach Gehres is very happy with the experience that young wrestlers have gotten this season, and the Owls look forward to another great season next year.
February 27, 2006 in Wrestling | Permalink