Apple picking season is here and if you want a taste of fall in a blondie then my Caramel Apple Bars will be your new favorite sweet treat.
I think fall is my favorite time of year. The heat of the summer is gone and the weather is crisp and sunny. A few months of nice weather before daylight wains and the air turns cold. Another favorite, this time of year, is apple picking at our local u-pick apple farm.
We have been taking the kids to pick apples for years. Last year I posted a recipe for Apple Harvest Mini Breads along with great pictures of Ella enjoying the farm and picking apples.
I think she mostly likes the homemade apple fritters the farm makes, but she also likes being outdoors. This year I decided to make these incredibly moist Caramel Apple Bars.
These bars are the quintessential flavor of fall. Just imagine sitting around the fire-pit with a warm cup of cider while taking a bite of these delicious bars.
What is your favorite apple recipe??
Grease a 9" x 13" baking pan and line with parchment paper, leaving a slight overhang.
In a large bowl, beat the sugars and butter with an electric mixer, on medium, until light and fluffy, about 3 minutes.
Slowly add the flour mixture to the butter mixture and beat to combine.
Fold in the apples, walnuts and butterscotch chips.
Bake 20 to 25 minutes until a toothpick inserted into the center comes out with moist crumbs. Transfer the pan to a rack to cool completely.
Lift the bars out using the parchment overhang and transfer to a cutting board.
Love this! They look delish and perfect for Fall!
Caramel and apple has to be two of my favorite bakery flavors. These bars look amazing and I can't wait to give them a try!
Thanks Julie. They are delicious!
These look great, fall is my favorite season too! Pinning to try it out.
Thanks Jacqueline. They are wonderful. Thanks for pinning!
These bars look wonderfully fragrant and delicious…and as it so happens, we're planning on going apple-picking tomorrow! I can't wait for all the apple-y treats! Thanks for sharing the recipe.
We are going to an apple festival this weekend and maybe do some picking. Have a great time.
She will love them. My family couldn't stop eating them!
oh my such tasty little morsels!! Thanks for sharing on the What's for Dinner link up!
Those bars looks mighty tasty. I am wild about caramel…and add apple, brown sugar and butter, and you can't go wrong! Thanks so much for sharing with us at Weekend Potluck.
Thanks Marsha! Yes, you can't go wrong with these flavors. Have a great week.
Love these bars! Thanks for linkin' up with What's Cookin' Wednesday!
Thanks Karly. They are so good and perfect for fall. Thanks for hosting the party.
This looks so yummy! I love everything caramel apple. Thanks for joining the Family Joy Link Party!
These bars look delicious. Love apple season! Will be pinning.Thanks for sharing on Family Joy Blog Link-up. Please come back and join us again! Remember to leave your host a comment to increase the chance of being featured.
Thanks Charlotte. Have a great weekend!
Yum! This is going on my must make list. Thanks for sharing at Snickerdoodle. I'll be featuring your Caramel Apple Bars at tomorrow's party.
Thanks Beverly. I made another batch this weekend. They are wonderful!
These sound incredible! I am definitely giving them a try soon. Thanks for linking up with Merry Monday!


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Megopis sulcipennis är en skalbaggsart som först beskrevs av White 1853.  Megopis sulcipennis ingår i släktet Megopis och familjen långhorningar.

Artens utbredningsområde är:
 Burma.
 Nepal.

Inga underarter finns listade i Catalogue of Life.

Källor

Långhorningar
sulcipennis

redpajama_set_name: RedPajamaWikipedia


text:
All events that happened in 2010.
January[edit]
3rd: "Thursdays with Abie" aired for the first time.
10th: "Once Upon a Time in Springfield" aired for the first time.
11th: The Simpsons: Access All Areas aired for the first time.
12th: The Simpsons: Mischief & Mayhem aired for the first time.
The Complete Twentieth Season is released on DVD for North America.
13th: The Simpsons: Celebrity Friends aired for the first time.
14th: The Simpsons 20th Anniversary Special – In 3-D! On Ice! aired for the first time.
20th: The Complete Twentieth Season is released on DVD for Australia.
31st: "Million Dollar Maybe" aired for the first time
February[edit]
14th: "Boy Meets Curl" aired for the first time.
21st: "The Color Yellow" aired for the first time.
March[edit]
14th: "Postcards from the Wedge" aired for the first time.
21st: "Stealing First Base" aired for the first time.
28th: "The Greatest Story Ever D'ohed" aired for the first time.
April[edit]
11th: "American History X-cellent" aired for the first time.
16th: Daryl Gates, a guest star in the special Springfield's Most Wanted, died.
18th: "Chief of Hearts" aired for the first time.
21st: Ron Scalera, production manager, died.
25th: "The Squirt and the Whale" aired for the first time.
May[edit]
1st: Bongo Comics Free-For-All 2010 is released on Free Comic Book Day.
2nd: "To Surveil with Love" aired for the first time.
9th: "Moe Letter Blues" aired for the first time.
16th: "The Bob Next Door" aired for the first time.
23rd: "Judge Me Tender" aired for the first time.
Season 21 finished.
28th: Gary Coleman, actor and guest star, died.
June[edit]
12th: Al Williamson, comic artist, died.
July[edit]
26th: Ben Keith, a steel guitar player, died.
August[edit]
24th: The Complete Thirteenth Season is released on DVD for North America.
September[edit]
3rd: Robert Schimmel, comedian and guest star, died.
10th: The Simpsons SU2C PSA aired for the first time.
20th: The Complete Thirteenth Season is released on DVD for the United Kingdom.
26th: Season 22 started.
"Elementary School Musical" aired for the first time.
30th: Simpsons World The Ultimate Episode Guide: Seasons 1-20 was released in the United Kingdom.
October[edit]
3rd: "Loan-a Lisa" aired for the first time.
10th: "MoneyBart" aired for the first time.
26th: Simpsons World The Ultimate Episode Guide: Seasons 1-20 was released in the United States.
November[edit]
7th: "Treehouse of Horror XXI" aired for the first time.
11th: Season 23 was announced.
14th: "Lisa Simpson, This Isn't Your Life" aired for the first time.
21st: "The Fool Monty" aired for the first time.
28th: "How Munched Is That Birdie in the Window?" aired for the first time.
December[edit]
1st: The Complete Thirteenth Season is released on DVD for Australia.
5th: "The Fight Before Christmas" aired for the first time.
12th: "Donnie Fatso" aired for the first time.
Retrieved from "https://simpsonswiki.com/w/index.php?title=2010&oldid=833396"
Modified on June 9, 2018, at 12:46.

redpajama_set_name: RedPajamaCommonCrawl


Welcome to the PROGRESS Annual Survey!
Gender equality (supports the effective implementation of the principle of gender equality and promotes gender mainstreaming in all EU policies).
Each of these policy sections has their own separate questionnaire, which are similar in structure, but are adjusted to the outcomes and outputs of the concrete policy section. Each questionnaire consists of multiple choice questions and should take you around 15 minutes to complete. The questionnaires are available in English, French and German. Your responses will be kept strictly confidential and will not be divulged to anyone.
To start the survey, please select the appropriate questionnaire available below, which best matches your area of competence. For authentication purposes, we would request that you provide your e-mail address. Within a few minutes you will receive further instructions and the link to the online questionnaire.
For those with more than one area of competence, please note that on completing a questionnaire you will be given the chance to return to this page to access the other questionnaires dealing with the remaining policy sections.
We would be grateful if you could complete the questionnaire by 31 January, 2014.
This survey requires confirmation by e-mail. For more information please consult our specific privacy statement (available in English).


Youre here: Home » Children's Stories » Children's Bible Stories » Stories from the New Testament » The Unjust Judge.
"AVENGE ME OF MY ADVERSARY."
N A CERTAIN city there was a judge who neither feared God nor cared for man. And in the same city there was a widow that had an enemy, and he had done her an injury.
And she came to the judge and implored him, saying, "Give me justice; avenge me of my adversary."
Then the widow came to him every day and cried, "Give me justice;" but still he would not for a long while.
At last he became wearied of her constant cry, and he said within himself, "Though I fear not God nor care for man, yet, because this widow troubleth me with her complaint, I will avenge her; lest by her continual coming she weary me."
And Jesus said, "Hear what the unjust judge saith. And if he, who was an unjust judge and a wicked man, would grant the widow's petition, because she asked so often, will not God, who is good and just, give His children what is good and right for them? Shall not God avenge His own elect, which cry day and night unto Him, though He bear long with them?"
In this parable Jesus impressed upon his disciples the truth that, although great trials might come upon them, and their lives be in peril, yet they were not to lose faith in God, or be disappointed because their prayers were not answered at once.
They were to keep on praying; asking God for such things as were right, and trusting that He would preserve them amidst all their enemies; and in His own way make them to triumph over their foes. Whatever is best for His people, God will give them. He cares for the sparrows, and, even more, for those who love Him.


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Clinical Use Of Keto 🏥
Emerging data suggest a possible therapeutic utilization of ketogenic diets in multiple neurological disorders apart from epilepsy, including head ache, neurotrauma, Alzheimer's and Parkinson's disease, sleep disorders, brain cancer, autism and multiple sclerosis.
Ariadna Rodríguez
Since the introduction of keto in 1920, research has emerged to understand its mechanisms and uses in various clinical conditions and, recently, ketones have been proposed as super-metabolic fuel because of their various favorable impacts on cellular metabolism in many tissues.
Up until now, these are the disorders that are being treated with the ketogenic diet:
Endocrine Disorders: Diabetes, Obesity, Metabolic Syndrome, PCOS, Conegnital hyperinsulinism, Non-Alcoholic Fatty Liver Disease (NAFLD).
Neurological Disorders: Intractable Epilepsy, Lennox-Gastaut syndrome, Myoclonic-astatic epilepsy, Parkinson's Disease, Alzheimer's Disease, ALS, Migraines, Narcolepsy, Depression, Autism.
Metabolic Disorders: Glucose transporter type 1 deficiency, Pyruvate dehydrogenase complex deficiency, Phosphofructokinase deficiency.
Others: Trauma and ischemia, Cancer and malignancy.
But, is it safe? 🤨
Our ketone build-up depends on several physiological parameters such as body fat percentage, body mass index (BMI), and resting metabolic rate; that's why keto should ideally be supervised by a registered dietitian - nutritionist (among other professionals).
Keto is perfectly safe as the concentration of ketones in persons on this diet is far lower than the concentration seen in diabetic ketoacidosis (a really severe and life-threatening state that has nothing to do with ketosis) and is not associated with any changes in blood pH.
It must be mentioned here that human nutrition begins with a keto diet…Colostrum is 100% keto and serves the needs of the neonate completely.
Impact on central nervous system 🧠
There are studies supporting possible therapeutic utilization of keto in multiple neurological disorders due to its neuroprotective effects.
Keto is considered an established part of an integrative approach, along with drug therapy, in major epilepsy centers worldwide.
The transition from glucose to ketones can metabolically target brain tumors and reduce their energy metabolism to avoid tumor growth.
Impact on heart 🫀
The cardiac muscle is an "omnivore," which uses diverse substances as sources of fuel, being ketones one of them. Studies have shown an increase in the number of mitochondria, tolerance to ischemia (an inadequate blood supply to an organ or part of the body, especially the heart muscles), and a faster recovery of cardiac function following reperfusion (restoration of blood flow to an organ or tissue after having been blocked) in rats fed with a ketogenic diet*; hence, it is cardioprotective.
*Similar benefits have been observed in human model studies.
Impact on respiratory system 🫁
Studies have shown that keto can help in respiratory problems with limited oxygen supply, which proves beneficial for patients with respiratory insufficiency or failure.
As you can see, keto is gaining interest but is to be performed under strict medical supervision of dieticians/nutritionists and physicians to be effective. With that being said, the understanding of clinical impacts, safety, tolerability, efficacy, duration of treatment, and prognosis after discontinuation of the diet is challenging and requires further studies to understand the disease-specific mechanisms.


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'Harry Potter Party Fest' Taking Place In Buffalo This Weekend
Chris Owen Published: September 20, 2021
Let's be honest, Harry Potter is more than just a popular book and movie series -- it's a way of life for many here in Western New York and around the world.
Harry Potter unites people together with its entertaining and interesting backstory, games, literature, and merchandise. If you love Harry Potter, chances are you have Harry Potter stuff in your possession and certainly belong to one of the houses (Hufflepuff, Slytherin, Gryffindor, Ravenclaw).
Calling all Harry Potter fans -- there is a Harry Potter party taking place in Downtown Buffalo this Sunday, and it sounds like a dream come true.
It's called Harry Potter Party Buffalo! and will take place at Mohawk Place on E. Mohawk Street in Buffalo this Sunday at 7 pm.
This Harry Potter fest will include trivia, games, Quidditch, a scavenger hunt, vendors, performers, themed drinks and food, and so much more. It's a Triwizard Tournament!
For those going, you don't have to dress up, just wear your house colors! You know, black and yellow for Hufflepuff, green and black for Slytherin, red and gold for Gryffindor, and black and purple for Ravenclaw.
Those attending must be 18 or older, or 16-17 with an accompanying adult 21+. Nobody under 16 will be allowed.
UPDATE: Tickets for this event are sold out, but Wizard Fest will be bringing a Harry Potter Party to a few dozen locations through the end of the year, including more northeast locations.
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Filed Under: buffalo, Buffalo Events, Harry Potter
Categories: Arts & Culture, Buffalo Events, WNY News
10 Fun Events Happening This Weekend In Western New York


The International Commercialization Forum is an exclusive gathering of global thought leaders and practitioners from academia, business, government and industry all focusing on building robust, sustainable companies that are based on the results of publicly funded research.
Hosted by the Ontario Centres of Excellence`s Centre for Commercialization of Research (CCR), the Forum will take place in Ottawa, Ontario, Canada on March 30th and 31st, 2011. Participation is by invitation only.
During the two-day Forum, this select group of experts will engage in interactive sessions to discuss exemplary practices in commercializing research results and evidence-based effective innovation models from around the world. Participants will share the most compelling novel ideas to improve the state of global innovation.
Create an International Commercialization Alliance as an ongoing forum for discussion and exchange of knowledge and ideas.
I am pleased to nominate Rich Bendis, President and CEO of Innovation America as a top 5 candidate in the Innovation and Creativity category. Rich is a globally recognized leader, practitioner and speaker on Innovation. Over the past 25 years he has successfully created, managed and advised some of the top innovation-based economic development organizations in the world.
As publisher, Rich posts 25 new Innovation related articles every day and his publication is read in 185 countries. His demand continues to increase as an "Innovation Evangelist" which has now reached 5 Continents, numerous Countries and their innovation leaders. His inspirational speaking engagements are all by referrals as he delivers and exceeds his audience's expectations.
Rich Bendis is truly worthy of this recognition as a Top Innovation speaker.
Scroll Down to section 7 "7) Current Leading Nominations in Innovation / Creativity"
Press the "Submit Nomination Form"
In a lingering recession, seed money to develop new technologies in the private marketplace is more difficult to find than ever. But for intrepid entrepreneurs with good—no, make that great—ideas, the federal government is willing to help. An array of programs designed to help move new technology to the marketplace and spur the economy exists across the federal spectrum.
Not surprisingly, the Small Business Administration is at the forefront of this effort with its Small Business Innovation Research (SBIR) and Small Business Technology Transfer programs (STTR).
SBIR allows qualified small businesses to compete for research and development financing by proposing innovations that meet the needs of the federal government. The program is a highly competitive, three-phase award system, specifically designed to fund research and development activities that private sector investors may label "too early" or "too risky." SBIR, and its sister, STTR, encourage small firms to undertake scientific research that helps meet federal R&D objectives, and have high potential for commercialization if successful.
The German Center for Research and Innovation (GCRI), in cooperation with HANNOVER MESSE Research & Technology, the leading international trade fair for R&D and technology transfer in Hannover, Germany, hosted a panel discussion on national frameworks, practices, and funding schemes for early- stage high-tech companies in the U.S. and Germany on October 26, 2010. At the German House New York, Richard Bendis, President & CEO of Innovation America, Edward Reinfurt, Executive Director of the New York State Foundation for Science, Technology and Innovation, and Christos Christodoulatos, Associate Provost to the Office of Academic Entrepreneurship, Stevens Institute of Technology, discussed how to adopt best practices and to access seed money to establish university spin-offs and other successful examples of research commercialization. Kurt Becker, Associate Provost for Research and Technology Initiatives and Professor of Physics at the Polytechnic Institute of New York University, moderated.
Referring to the 7th Annual Conference of the Technopolicy Network, which took place in Heidelberg, Germany, on September 30 and October 1, 2010, the first speaker Richard Bendis said that transatlantic knowledge clusters are an emerging and growing trend.
However, one of the challenges for small businesses, according to all speakers, is the relationship between competing in a global market and international collaboration. Mr. Bendis, a seasoned entrepreneur with experience as a corporate executive and venture capitalist, gave an overview of the Small Business Innovation Research (SBIR) program, which has been supporting small businesses since 1982. While in Germany the first research program was established at a Berlin university as early as 1821, in the U.S., the impetus for innovation historically has come from the adoption of technology from military to private market use. The 1982 SBIR/STTR (Small Business Technology Transfer) programs represent one of the first national policies intent on systematically fostering innovation in the U.S. alongside state-level economic development initiatives. Additional programs were initiated by the Clinton and Obama administrations in the 1990s and 2000s.
The answer to improving Iowa's economy lies more with igniting startup companies such as BodyViz, Dwolla and Sensr than luring big companies like Google, IBM and Microsoft to the state, influential business leaders believe.
Members of the newly created Iowa Innovation Council say the state needs to drive its economy through innovation, a long-term structural change that promises Iowans better-paying jobs.
The group plans to start a seed fund, used to invest in young companies, raising as much as $100 million in private investment within three years. The fund would invest $500,000 to $3 million in promising startup companies, targeting bioscience, advanced manufacturing and information technology, organizers say.
Richard Bendis is an accomplished entrepreneur, corporate executive, venture capitalist, investment banker, technology-based economic development leader, international speaker and consultant in the technology, health-care and innovation development industries.
Bendis is the founding president and CEO of Innovation America, a national private/public partnership focused on accelerating the growth of the U.S. entrepreneurial innovation economy. He also founded the Bendis Investment Group, a financial intermediary and consulting firm. Bendis recently provided interim CEO consulting services to the National Association of Seed and Venture Funds and strategic growth and repositioning services to the Pennsylvania Biotechnology Center.
entre empresários e dirigentes empresariais dos três países.
com a audiência as últimas novidades em termos de inovação.
mais potencial para inovar", observou.
Rich Bendis (NASVF Vice Chair and President/CEO Innovation America) participates in the session "Early Stage Business: Building Strategies That Work" with Rich Lunak (Innovation Works), Lisa Delp (Ohio Department of Development) and moderator Mark Huston (Cimarron Capital Partners).
WHEELING - West Liberty University President Robin Capehart and Huntington-based hip-hop artist K-Kutta come from different backgrounds, but both believe entrepreneurship is key to West Virginia's future.
"We need job creators. We need people that have the will to go out and take a risk, like these gentleman have done," Capehart said of Kutta and Luke Glass, vice president of Morgantown-based ListHub.net, during the final day of the 2010 Create West Virginia conference Tuesday at Oglebay Park's Wilson Lodge.
Folks from all over West Virginia came to the Wheeling conference to help find ways to develop the state's new economy.
During the Tuesday panel discussion regarding the benefits of starting new businesses in the Mountain State, Capehart said West Liberty is making a commitment to ensuring students realize they do not have to work for someone else when they graduate.
Only 15 University Sponsor Slots Left!
The University Startups Conference will take place December 1-3, 2010 at the Washington Convention Center, Washington, DC.
The University Startups Conference is a unique conference series dedicated exclusively to creating and funding university startups. We bring together universities creating startups with VCs, angel investors, Federal Government program managers and Fortune 500 companies that fund them.
The Conference is organized annually by the National Council of Entrepreneurial Tech Transfer (NCET2.org). This year's University Co-Hosts are the University of Maryland and Boston University. The Government Co-Hosts are the National Science Foundation (Division of Industrial Innovation and Partnership) and National Institutes of Health (Office of Tech Transfer). The Embassy Host is the British Embassy. The venture capital sponsors are the National Venture Capital Association (NVCA) and the National Association of Seed and Venture Funds (NASVF).
The German Center for Research and Innovation (GCRI), in cooperation with Hannover Messe Research and Technology, the leading international trade fair for R&D and Technology Transfer in Hannover, Germany, will host a panel discussion on the national frameworks, practices, and funding schemes for early-stage high-tech companies in the United States and Germany. The event will take place on Tuesday, October 26, from 6:30 to 8:30 p.m., at the German House New York (871 United Nations Plaza, btw. 48th & 49th Streets).
Richard Bendis, President & CEO of Innovation America, Edward Reinfurt, Executive Director of the New York State Foundation for Science, Technology and Innovation, and Dr. Thomas Lechler of the Howe School of Technology Management at Stevens Institute of Technology will discuss best practices, accessing non-domestic sources of seed money to establish university spin-offs and the effects of the world economy on tech transfer, tech commercialization, and finance. Their discussion will include examples, opportunities, and obstacles of international collaboration. Of particular interest for public and private sector technology transfers and technology marketing managers, venture capital and economic development professionals, the panel will also focus on other vehicles of successful research commercialization. Kurt Becker, Associate Provost for Research & Technology Initiatives and Professor of Physics at the Polytechnic Institute of New York University, will moderate.
WHEELING - The spirit of innovation is running wild in Wheeling, as the 2010 Create West Virginia conference is set to go at different locations throughout the city next week.
"The new economy is about research, technology, arts and culture, and innovation," said Create Chairman Jeff James. "We are teaching local communities how to use tried and true strategies to build that new economy."
The conference - which James said should draw 250-275 people from all over West Virginia and the United States - begins at noon Sunday at Oglebay Park.
Richard Bendis, fundador e presidente executivo da Innovation America, defende que "Portugal deve concentrar esforços em clusters em que é competitivo". Para este consultor norte-americano, que proferiu uma conferência na cimeira da COTEC — Associação Empresarial para a Inovação realizada esta semana no Porto, Portugal deve melhorar a imagem de país inovador no estrangeiro.


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Megastigmus lasiocarpae is een vliesvleugelig insect uit de familie Torymidae. De wetenschappelijke naam is voor het eerst geldig gepubliceerd in 1913 door Crosby.

Torymidae


What exactly is an Octadecagon? At Lothlorien Woods our "Yurt" is an 18-sided, custom-built and exquisitely appointed wilderness cabin unlike any other. Over two years in construction, Roy Conant, allowed the spirit of the "Yurt" and the materials incorporated therein to guide the realization of a sweet, peaceful, and relaxing accessible wilderness respite, Accessible from inside the "Yurt" is a bathroom with a roll-in shower with seat and other facilities with transfer provisions.
Largely constructed from materials lovingly and gently harvested on-site, the Yurt at Rivendell is a sanctuary of peace and serenity, a place for rejuvenation and inspiration. Step back in time to a stress-free existence while the sun, the moon and the stars wink at you through the gentle undulations of the 100 year-old Douglas Firs Trees and the "Dome" of the Yurt itself. Relish the radiance of tranquility in your sojourn to heartsease and inspiration.
The Yurt at Rivendell is "Glamping" at its finest, proffering essential amenities of the built world in a completely natural and stunningly beautiful environment. Whatever the season (Our Respite at Rivendell is available year-round) you are bound to be enthralled by the natural spectacle of nature and the opportunities therein to animate, energize, and satiate your entire being -- body, spirit, and soul!
You can contact Roy through the Contact Host button on this page. If you've already booked, go to My travels.
Interested in more accommodations around White Salmon?


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The worst ever? Was Iran disqualified from World Cup?
The Qatar World Cup has yet to start, but many fans feel it will surpass the 2002 World Cup as the worst World Cup in history
World Cup News∥UK bans fans from leaving, FIFA ranking update!
The 2022 World Cup is approaching, with only one month left before the start of the tournament.
Germany vs. Spain in the World Cup|Favorite Soccer Games Handicap Analysis!
Which team are you looking for in the Qatar World Cup? Group E of the World Cup group stage can be said to be the current group of death
Defensive responsibilities! A look at the top five current center-backs at the 2022 World Cup!
Everyone who mentions football immediately thinks of famous players like Messi and Neymar. These players are strikers
Inventory of those bleak stars who missed the World Cup football stage!
When it comes to the popular stars of the 2022 World Cup, everyone must first think of dazzling stars such as Messi and Ronaldo.
World Football's labor problem explodes again! Unpaid migrant workers are deported!
In less than 100 days, the Qatar World Cup will begin! This is good news. However, not long ago, the labor problem in Qatar broke out again
World Cup tickets are not sold out? About the 2022 World Cup Soccer Tournament!
The countdown to the quadrennial World Cup has officially begun. Qatar is the first World Cup to be held in a Middle Eastern country
Qatar proposes a schedule change! Will the 2022 World Cup opening match be rescheduled?
According to the customer from the 2006 World Cup, the host country will play the opening game of the World Cup.
The strongest curse! France can't escape the fate of the 2018 World Cup defending country?
Fans who have a certain understanding of the World Cup should have heard of the curse of the World Cup, right?
2022 World Cup Argentina Messi success or failure pre-match detailed explanation!
The Argentine national team was established in 1893. Argentina's Messi has won 20 major national team titles at the 2022 World Cup
2022 Qatar Football World Cup pre-match champion team prediction!
The 2022 Qatar Football World Cup will open in the Middle East country Qatar! This is a carnival feast for fans every four years!
2022 World Football Lottery Odds ➕ Analysis Information!
The 2022 Qatar World Cup will be held at the end of the year. Lottery companies have disclosed the odds of winning the championship
【Kirin Cup】Japan wins over Ghana to warm up for the World Cup Group of Death!
After the 2022 World Cup qualifying rounds, the Kirin Cup will follow
Beyond racism! Soccer World Cup: The Myth of Black Players Debunked!
Recently, the issue of bullying in World Cup football has been discussed again.
Overworked stars cause the five major leagues to overlap with the world football season?!
Europe's five major leagues have announced the game times for the 22-23 season.
【Sports Lottery Play】Football Handicap Prediction Skills!
In a few months, the World Cup will begin. How much do you know about lottery terminology?
World Cup players are afraid! Qatar Hotel does not take FIFA into account!
Qatar, the host country of the 2022 FIFA World Cup, is the first Middle Eastern country to host the World Cup.


The Particle CLI is a powerful tool for interacting with your devices and the Particle Device Cloud. The CLI uses Node.js and can easily run on Windows, macOS (OS X), and Linux. It's also open source so you can edit and change it, and even send in your changes as pull requests if you want to share!
This command downloads the particle command to your home directory at ~/bin, installs a version of Node.js to ~/.particle and installs the particle-cli Node.js module that contain the code of the CLI.
It will also try to install DFU-util, a utility program for programming devices over USB. See the instructions for installing DFU-util if the installer is not able to automatically install dfu-util.
The installer also works on the Raspberry Pi!
Download the Windows CLI Installer and run it to install the Particle CLI, the device drivers and DFU-util. You may see a Windows Defender SmartScreen warning when running the Windows CLI Installer if you are one of the first people to run the installer after a new release.
The CLI is installed to %LOCALAPPDATA%\particle (C:\Users\username\AppData\Local\particle for Windows in English).
You can manually install the particle-cli Node.js package if you need the CLI installed in a different location or you need to install a specific version of the CLI.
Make sure you have a recent LTS version of Node.js installed.
If you experience permission errors, we recommend you change the directory where npm installs global packages (ones installed with -g) to another directory as documented here. If you must install particle-cli to the default global package location as the superuser, you have to use the --unsafe-perm flag to successfully install all dependencies: sudo npm install -g --unsafe-perm particle-cli.
For more OS-specific install instructions, see below.
To use the local flash and key features you'll also need to install dfu-util, and openssl. They are freely available and open-source, and there are installers and binaries for most major platforms.
If you installed the Particle CLI through the installer, it will periodically update itself to the latest version.
If the CLI is outputing unexpected errors after an update, delete the ~/.particle (macOS and Linux) or C:\Users\<username>\AppData\Local\particle directory and run the installer script again to start over.
If you installed manually using npm install, you can upgrade by running the same command you used to install the tool.
These next two commands are all you need to get started setting up an account, claiming a device, and discovering new features.
This command will guide you through logging in or creating a new account as well as claiming your device!
Shows you what commands are available and how to use them. You can also give the name of a command for detailed help.
If you're wanting to save data on your Electron you should definitely consider flashing your Electron over serial instead of OTA (over-the-air).
Assuming you've compiled and downloaded the firmware binary from Build IDE by clicking the cloud button next to the file name, you should be able to use the Particle CLI, mentioned above, to flash your application firmware to your Electron without using data.
2: Open a command prompt or terminal window.
3: Navigate to the folder where you've downloaded the firmware.bin file.
Note: If your Electron goes into safe mode, this is okay, just make sure that the Device OS version you have on the device matches the dependency of the Device OS version used to compile the application firmware.
Let's make sure your device is online and loaded with Tinker. We should see the four characteristic functions exposed by Tinker, "digitalWrite", "digitalRead", "analogWrite", and "analogRead".
Let's try turning on the LED attached to pin D7 on your device.
Nice! You should have seen the small blue LED turn on, and then off.
You can write whole apps and flash them remotely from the command line just as you would from the build IDE. Let's write a small blink sketch to try it out.
Then let's compile that program to make sure it's valid code. The CLI will automatically download the compiled binary of your program if everything went well.
Now that we have a valid program, let's flash it to our device! We can use either the source code again, or we can send our binary.
You can find a step-by-step guide to installing the local build toolchain for the firmware in the FAQ section of the documentation.
After building your code on your machine, you can flash it to your device over Serial or remotely.
When your code gets too long for one file or you want to use libraries that other developers have contributed to the Particle platform it's time to create a project.
By default projects are created in your home directory under Particle or in your Documents folder under Particle on Windows. You can also create projects in the current directory.
The CLI supports using libraries with your project. This allows you to incorporate already written and tested code into your project, speeding up development and assuring quality.
These commands are described in more details in the CLI reference.
The library search command allows you to search for libraries that are related to the text that you type in.
Will find libraries containing neo in their name.
The library add command adds the latest version of a library to your project.
> Library InternetButton 0.1.10 has been added to the project.
> To get started using this library, run particle library view InternetButton to view the library documentation and sources.
This will add the InternetButton dependency to your project's project.properties file.
The InternetButton library itself is not present in your project, so you won't see the InternetButton sources. The library is added to your project when the project is compiled in the cloud.
To make the library functionality available to your application, you add an include statement to your application source code. The include statement names the library header file, which is the library name with a .h ending.
The library view downloads the source code of a library so you can view the code, example and README.
Change to the directory indicated to view the sources.
Adding a library to your project does not add the library sources. For times when you want to modify the library sources, you can have them added locally.
The library will be copied to the lib folder of your project. If you already have the library in your project.properties make sure to remove it so the cloud compiler doesn't overwrite your changed copy with the published code.
The functions and classes from that library are then available for use in your application. Check out the library examples and documentation that comes with the library for specifics on using that library.
Contributing a library is the process where you author a library and share this with the community.
While it's not strictly necessary to have a project present when authoring a new library, having one can help ensure that the library works as intended before publishing it. The project allows you to consume the library, check that it compiles and verify it behaves as expected on the target platforms before publishing.
The library will exist in the directory lib/mylib.
All these files are initially empty - we'll add content to them as the library is authored.
The library create command is used to scaffold the library. It creates a skeleton structure for the library, containing initial sources, examples, tests and documentation.
The command will prompt you to enter the name of the library - mylib, the version - 0.0.1 and the author, your name/handle/ident.
The command will then create the skeleton structure for the library.
You are then free to edit the .cpp and .h files in the lib/mylib/src folder to provide the functionality of your library.
It's a good idea to test often, by writing code in the consuming project that uses each piece of functionality in the library as it's written.
This will create a .bin file which you then flash to your device.
Before the library is contributed, it is first validated. If validation succeeds, the library is contributed and is then available for use in your other projects. The library is not available to anyone else.
If you wish to make a contributed library available to everyone, it first needs to be published.
When publishing a library, it's important to ensure the version number hasn't been published before - if the version has already been published, the library will not be published and an error message will be displayed.
Incrementing the version number with each publish is a recommended approach to ensuring unique versions.
Once the library is published, it is visible to everyone and available for use. Once the a given version of a library has been published, the files and data cannot be changed. Subsequent changes must be via a new contributed version and subsequent publish.
For more info on CLI commands, go here.


Bright Green at 100% Design.
With Designjunction making the move to Kings Cross this year, the new venue featured this green installation of Cubitt House designed by Satellite Architects and Icons of Denmark featuring the Grid cubes of Peter J. Lassen.
Delicate vases from Scandinavia Form at Nordic Fresh.
Love these self-contained indoor plants from Pikaplant. The jars don't need watering as the plants inside have everything they need. The coffee plants look gorgeous and healthy inside too and some have been thriving for years.
Grow Greenhouses by Caroline Wetterling at Design House Stockholm. Love the tiny spout on the dome that lets you use the dome as a watering can.
The Greenhouse by Atelier 2+ at Design House Stockholm.
Nature Lab from the Crafts Council and The New Craftsmen at the London Design Fair's British Craft Pavilion. Beautiful naturally inspired works by Eleanor Lakelin, Emily Gardiner, Jochen Holz, Joseph Harrington, Marcin Rusak, and Marl�ne Huissoud.
Knitted cacti from Yes We Knit.
The Bloomon secret garden at the London Design Fair.
Pandori, a pantry larder designed by Steph Leake and created by Jack Badger for creperie Nojo. The design combines Japanese and English joinery techniques and even includes a drawer for growing pink oyster mushrooms.


Srm_ps.dll file is part of Microsoft® FSRM internal proxy/stub product developed by Microsoft® Windows® Operating System. It is responsible for Microsoft Corporation functionality. This part is required for Microsoft® FSRM internal proxy/stub to function. If you are planning on replacing srm_ps.dll with a new version make sure that you backup your old file. Replacing srm_ps.dll file with a diffent version can cause Microsoft® FSRM internal proxy/stub to malfunction.


HOW DO DEMONS GAIN ENTRY INTO PEOPLE'S LIVES?
DO CHRISTIANS EVER NEED DELIVERANCE FROM DEMONS?
In this readable, biblically based book, Derek Prince answers these and many other vital questions. If you are struggling with problems that never seem to go away, has it ever occurred to you that demons may be at work? Or perhaps you want to help others with such problems.
Derek Prince points out that "Jesus never sent anyone out to preach the Gospel without specifically instructing and equipping them to take action against demons in the same way that He Himself did."
If this is not true today, Prince asks, "Who has change? Jesus? The demons? The Church?"
Derek Prince (1915-2003), founder of Derek Prince Ministries International, wrote more than fifty books. He was educated at Eton College and Cambridge University and studied Hebrew and Aramaic at Cambridge and at the Hebrew University in Jerusalem. His daily radio broadcast, Derek Prince Legacy Radio, still reaches listeners around the world.
As a traditional, Southern Baptist pastor I had heard little teaching (even in three years of Baptist seminary) on the subject of demons. Like most evangelicals, I accepted by faith the scriptures on Christ casting out demons. However, I saw little relevance to the practice today. After all, I had been told often that it was only for the New Testament era. (I thought). This book was an eye-opener.
It is Biblical, and conservative in its tone and teaching. It is also real. It highlights the active presence and purposes of demonic forces today, but most importantly, how the believer in Jesus Christ can deal with them in the authority of Christ. How I wish the evangelical world would take the presence and activity of demons seriously. Perhaps more will, through this book.


Kitchen Small Kitchen Paint Colors With White Cabinets. Never underestimate the power of great paint colors for small kitchens! Instead of a major overhaul, simple paint on kitchen walls and cabinetry can provide the lift needed to update and open up the confines of a small kitchen. Best 20+ Kitchen Paint Color Ideas. Kitchen Paint Color Ideas You have neat and cozy enough kitchen to cook and it doesn't matter although it is a small kitchen. 9. Black and Red Colors google images. For those who like to use black in any kind of applications, you can also apply it on your kitchen. Just create a modern kitchen design along with bold black color. Combine it with bold red and white. Those three bold colors Best Kitchen Cabinet Colors For Small Kitchens (with Pictures. There are certain colors that simply work best with a kitchen. One of the most popular is white or off-white. This color works as it helps make your kitchen look a little bigger, and it helps keep things pretty, but there is one small hiccup: stains.
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The Company was established in Mauritius as a public company limited by shares holding a Category 1 Global Business Licence.
and logistics/warehouse property assets in the United Kingdom ("UK") and mainland Europe.
The Company's results are reported in pounds sterling ("GBP").
loss of GBP 11.00 million (2018: profit of GBP 2.79 million).
Estimated Rental Value ("ERV") and 90.63% (30 November 2018: 91.56%) by Gross Lettable Area ("GLA").
value ("LTV") covenants being exceeded.
funders, its loan terms are effectively repayable on demand.
its obligations in the normal course of business and will continue as a going concern.
to dispose of its property in Dublin.
of the Company from the JSE and SEM.
of its debt and working with all stakeholders to protect the value of its assets and the business.
sector is likely to continue to suffer.
Board of the Company effective from the conclusion of that meeting.
The Board wishes to thank both Mr Thomas and Mr Heaney for their invaluable contributions to the Company.
and Remuneration Committee as Chairman.
The Board is not recommending the payment of a dividend.
assessment of the Group's ability to continue to trade as a going concern.
been applied to those external valuations to determine valuations as at 28 February 2019.
to be a going concern and these financial statements have been prepared on that basis.
in the statement of comprehensive income and cash flow statement in accordance with IFRS 5.
on all of the information contained in these financial results.
International Standard on Review Engagements 2410, "Review of Interim Financial Information Performed by the Auditor of the Entity".
with International Financial Reporting Standards.
Group may be unable to realise their assets and discharge their liabilities in the normal course of business.
A copy of the auditor's ISRE 2410 review report is available for inspection at the Company's registered office.
The directors take full responsibility for the preparation and fair presentation of these interim financial results.
has decided to discontinue its European warehouse investment business.
Frontier Properties will host an investor update conference call on Tuesday, 16 April 2019 at 11:00 (South African time).
Participants should ask to be joined to the New Frontier Properties call.
Registered Office of the Company at Chemin Vingt Pieds, 5th Floor, La Croisette, Grand Baie, Mauritius.
New Frontier Properties Ltd accepts full responsibility for the accuracy of the information in this communiqué.
The Company does not have any dilutionary instruments in issue.
Date: 15/04/2019 02:40:00 Produced by the JSE SENS Department. The SENS service is an information dissemination service administered by the JSE Limited ('JSE').


It's our pleasure to introduce our Winner of the Month of January 2018!
Dear Harold Weimer (Trip# 10049294), Congratulations!
It has been an honor and a privilege for Colony Limo and Transportation family to serve you.


This article was written by Matthew Hepburn, published on 18th August 2016 and has been read 5930 times.
Matthew is studying French and European Studies at Nottingham Trent University, and is preparing for his year abroad studying at the Université de Franche-Comté in Besan��on. Here is his advice about how to describe your language ability in interviews and on your CV, no matter which country you're in.
As a student of French, I often find it hard to describe my language ability to people. Sometimes people ask how fluent I am in French and I'm not always sure how to answer because knowing one's own ability in a language is a) quite hard and b) very subjective.
However, there are times when being able to describe your language ability in an objective and factual way is important. For instance, if an employer asks you to describe your language ability during a job interview, it would be easier to use a recognised language standard for describing language ability rather than being unsure what to say without under or over-selling your language competence.
This is where the 'Common European Framework of Reference for Languages' (CEFR) comes in. 'The CEFR is an international standard for describing language ability. It is used around the world to describe learners' language skills' (Cambridge English).
There is a scale ranging from A1 (beginner) to C2 (mastered a language). The test will ask you to complete grammar, vocab, reading and listening questions. Once done, you'll find out where you are on the scale. There may be tests online to do which will give you a score however, I don't know how reliable this would be. I completed an official test because I had to before applying for my Erasmus grant for my year abroad. The test is done before and after the year abroad to see how much my language ability has improved. The test is really useful and can be used to show employers your level of language in an objective and universal manner.
TV5 Monde has a similar test which isn't the CEFR but still may be useful to see your language ability in French. The test can be found here.


text:
BJPsych Open (4)
Nutrition Research Reviews (1)
Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants — RETRACTED
Katrina A. S. Davis, Jonathan R. I. Coleman, Mark Adams, Naomi Allen, Gerome Breen, Breda Cullen, Chris Dickens, Elaine Fox, Nick Graham, Jo Holliday, Louise M. Howard, Ann John, William Lee, Rose McCabe, Andrew McIntosh, Robert Pearsall, Daniel J. Smith, Cathie Sudlow, Joey Ward, Stan Zammit, Matthew Hotopf
Journal: BJPsych Open / Volume 5 / Issue 4 / July 2019
Published online by Cambridge University Press: 17 June 2019, e56
Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants – CORRIGENDUM
Journal: BJPsych Open / Volume 4 / Issue 5 / September 2018
Katrina A. S. Davis, Jonathan R. I. Coleman, Mark Adams, Naomi Allen, Gerome Breen, Breda Cullen, Chris Dickens, Elaine Fox, Nick Graham, Jo Holliday, Louise M. Howard, Ann John, William Lee, Rose McCabe, Andrew McIntosh, Robert Pearsall, Cathie Sudlow, Joey Ward, Stan Zammit, Matthew Hotopf
Journal: BJPsych Open / Volume 4 / Issue 3 / May 2018
Published online by Cambridge University Press: 19 April 2018, p. 136
Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants
UK Biobank is a well-characterised cohort of over 500 000 participants that offers unique opportunities to investigate multiple diseases and risk factors.
An online mental health questionnaire completed by UK Biobank participants was expected to expand the potential for research into mental disorders.
An expert working group designed the questionnaire, using established measures where possible, and consulting with a patient group regarding acceptability. Case definitions were defined using operational criteria for lifetime depression, mania, anxiety disorder, psychotic-like experiences and self-harm, as well as current post-traumatic stress and alcohol use disorders.
157 366 completed online questionnaires were available by August 2017. Comparison of self-reported diagnosed mental disorder with a contemporary study shows a similar prevalence, despite respondents being of higher average socioeconomic status than the general population across a range of indicators. Thirty-five per cent (55 750) of participants had at least one defined syndrome, of which lifetime depression was the most common at 24% (37 434). There was extensive comorbidity among the syndromes. Mental disorders were associated with high neuroticism score, adverse life events and long-term illness; addiction and bipolar affective disorder in particular were associated with measures of deprivation.
The questionnaire represents a very large mental health survey in itself, and the results presented here show high face validity, although caution is needed owing to selection bias. Built into UK Biobank, these data intersect with other health data to offer unparalleled potential for crosscutting biomedical research involving mental health.
G.B. received grants from the National Institute for Health Research during the study; and support from Illumina Ltd. and the European Commission outside the submitted work. B.C. received grants from the Scottish Executive Chief Scientist Office and from The Dr Mortimer and Theresa Sackler Foundation during the study. C.S. received grants from the Medical Research Council and Wellcome Trust during the study, and is the Chief Scientist for UK Biobank. M.H. received grants from the Innovative Medicines Initiative via the RADAR-CNS programme and personal fees as an expert witness outside the submitted work.
Chapter 8A - Primary Amenorrhea in Pediatric and Adolescent Gynecology Practice
By Naomi S. Crouch, Lisa Allen
Edited by Sarah M. Creighton, Adam Balen, University of Leeds, Lesley Breech, Lih-Mei Liao
Book: Pediatric and Adolescent Gynecology
Print publication: 08 February 2018, pp 83-89
The acceptability of repeat Internet-based hybrid diet assessment of previous 24-h dietary intake: administration of the Oxford WebQ in UK Biobank
Julieta Galante, Ligia Adamska, Alan Young, Heather Young, Thomas J. Littlejohns, John Gallacher, Naomi Allen
Journal: British Journal of Nutrition / Volume 115 / Issue 4 / 28 February 2016
Print publication: 28 February 2016
Although dietary intake over a single 24-h period may be atypical of an individual's habitual pattern, multiple 24-h dietary assessments can be representative of habitual intake and help in assessing seasonal variation. Web-based questionnaires are convenient for the participant and result in automatic data capture for study investigators. This study reports on the acceptability of repeated web-based administration of the Oxford WebQ – a 24-h recall of frequency from a set food list suitable for self-completion from which energy and nutrient values can be automatically generated. As part of the UK Biobank study, four invitations to complete the Oxford WebQ were sent by email over a 16-month period. Overall, 176 012 (53 % of those invited) participants completed the online version of the Oxford WebQ at least once and 66 % completed it more than once, although only 16 % completed it on all four occasions. The response rate for any one round of invitations varied between 34 and 26 %. On most occasions, the Oxford WebQ was completed on the same day that they received the invitation, although this was less likely if sent on a weekend. Participants who completed the Oxford WebQ tended to be white, female, slightly older, less deprived and more educated, which is typical of health-conscious volunteer-based studies. These findings provide preliminary evidence to suggest that repeated 24-h dietary assessment via the Internet is acceptable to the public and a feasible strategy for large population-based studies.
Coordinated Microanalyses of Seven Particles of Probable Interstellar Origin from the Stardust Mission.
Andrew J. Westphal, Rhonda M. Stroud, Hans A. Bechtel, Frank E. Brenker, Anna L. Butterworth, George J. Flynn, David R. Frank, Zack Gainsforth, Jon K. Hillier, Frank Postberg, Alexandre S. Simionovici, Veerle J. Sterken, Carlton Allen, David Anderson, Asna Ansari, Saˇsa Bajt, Ron K. Bastien, Nabil Bassim, John Bridges, Donald E. Brownlee, Mark Burchell, Manfred Burghammer, Hitesh Changela, Peter Cloetens, Andrew M. Davis, Ryan Doll, Christine Floss, Eberhard Gru¨n, Philipp R. Heck, Peter Hoppe, Bruce Hudson, Joachim Huth, Anton Kearsley, Ashley J. King, Barry Lai, Jan Leitner, Laurence Lemelle, Ariel Leonard, Hugues Leroux, Robert Lettieri, William Marchant, Larry R. Nittler, Ryan Ogliore, Wei Jia Ong, Mark C. Price, Scott A. Sandford, Juan-Angel Sans Tresseras, Sylvia Schmitz, Tom Schoonjans, Kate Schreiber, Geert Silversmit, Vicente A. Solé, Ralf Srama, Frank Stadermann, Thomas Stephan, Julien Stodolna, Stephen Sutton, Mario Trieloff, Peter Tsou, Tolek Tyliszczak, Bart Vekemans, Laszlo Vincze, Joshua Von Korff, Naomi Wordsworth, Daniel Zevin, Michael E. Zolensky
Journal: Microscopy and Microanalysis / Volume 20 / Issue S3 / August 2014
By Aakash Agarwala, Linda S. Aglio, Rae M. Allain, Paul D. Allen, Houman Amirfarzan, Yasodananda Kumar Areti, Amit Asopa, Edwin G. Avery, Patricia R. Bachiller, Angela M. Bader, Rana Badr, Sibinka Bajic, David J. Baker, Sheila R. Barnett, Rena Beckerly, Lorenzo Berra, Walter Bethune, Sascha S. Beutler, Tarun Bhalla, Edward A. Bittner, Jonathan D. Bloom, Alina V. Bodas, Lina M. Bolanos-Diaz, Ruma R. Bose, Jan Boublik, John P. Broadnax, Jason C. Brookman, Meredith R. Brooks, Roland Brusseau, Ethan O. Bryson, Linda A. Bulich, Kenji Butterfield, William R. Camann, Denise M. Chan, Theresa S. Chang, Jonathan E. Charnin, Mark Chrostowski, Fred Cobey, Adam B. Collins, Mercedes A. Concepcion, Christopher W. Connor, Bronwyn Cooper, Jeffrey B. Cooper, Martha Cordoba-Amorocho, Stephen B. Corn, Darin J. Correll, Gregory J. Crosby, Lisa J. Crossley, Deborah J. Culley, Tomas Cvrk, Michael N. D'Ambra, Michael Decker, Daniel F. Dedrick, Mark Dershwitz, Francis X. Dillon, Pradeep Dinakar, Alimorad G. Djalali, D. John Doyle, Lambertus Drop, Ian F. Dunn, Theodore E. Dushane, Sunil Eappen, Thomas Edrich, Jesse M. Ehrenfeld, Jason M. Erlich, Lucinda L. Everett, Elliott S. Farber, Khaldoun Faris, Eddy M. Feliz, Massimo Ferrigno, Richard S. Field, Michael G. Fitzsimons, Hugh L. Flanagan Jr., Vladimir Formanek, Amanda A. Fox, John A. Fox, Gyorgy Frendl, Tanja S. Frey, Samuel M. Galvagno Jr., Edward R. Garcia, Jonathan D. Gates, Cosmin Gauran, Brian J. Gelfand, Simon Gelman, Alexander C. Gerhart, Peter Gerner, Omid Ghalambor, Christopher J. Gilligan, Christian D. Gonzalez, Noah E. Gordon, William B. Gormley, Thomas J. Graetz, Wendy L. Gross, Amit Gupta, James P. Hardy, Seetharaman Hariharan, Miriam Harnett, Philip M. Hartigan, Joaquim M. Havens, Bishr Haydar, Stephen O. Heard, James L. Helstrom, David L. Hepner, McCallum R. Hoyt, Robert N. Jamison, Karinne Jervis, Stephanie B. Jones, Swaminathan Karthik, Richard M. Kaufman, Shubjeet Kaur, Lee A. Kearse Jr., John C. Keel, Scott D. Kelley, Albert H. Kim, Amy L. Kim, Grace Y. Kim, Robert J. Klickovich, Robert M. Knapp, Bhavani S. Kodali, Rahul Koka, Alina Lazar, Laura H. Leduc, Stanley Leeson, Lisa R. Leffert, Scott A. LeGrand, Patricio Leyton, J. Lance Lichtor, John Lin, Alvaro A. Macias, Karan Madan, Sohail K. Mahboobi, Devi Mahendran, Christine Mai, Sayeed Malek, S. Rao Mallampati, Thomas J. Mancuso, Ramon Martin, Matthew C. Martinez, J. A. Jeevendra Martyn, Kai Matthes, Tommaso Mauri, Mary Ellen McCann, Shannon S. McKenna, Dennis J. McNicholl, Abdel-Kader Mehio, Thor C. Milland, Tonya L. K. Miller, John D. Mitchell, K. Annette Mizuguchi, Naila Moghul, David R. Moss, Ross J. Musumeci, Naveen Nathan, Ju-Mei Ng, Liem C. Nguyen, Ervant Nishanian, Martina Nowak, Ala Nozari, Michael Nurok, Arti Ori, Rafael A. Ortega, Amy J. Ortman, David Oxman, Arvind Palanisamy, Carlo Pancaro, Lisbeth Lopez Pappas, Benjamin Parish, Samuel Park, Deborah S. Pederson, Beverly K. Philip, James H. Philip, Silvia Pivi, Stephen D. Pratt, Douglas E. Raines, Stephen L. Ratcliff, James P. Rathmell, J. Taylor Reed, Elizabeth M. Rickerson, Selwyn O. Rogers Jr., Thomas M. Romanelli, William H. Rosenblatt, Carl E. Rosow, Edgar L. Ross, J. Victor Ryckman, Mônica M. Sá Rêgo, Nicholas Sadovnikoff, Warren S. Sandberg, Annette Y. Schure, B. Scott Segal, Navil F. Sethna, Swapneel K. Shah, Shaheen F. Shaikh, Fred E. Shapiro, Torin D. Shear, Prem S. Shekar, Stanton K. Shernan, Naomi Shimizu, Douglas C. Shook, Kamal K. Sikka, Pankaj K. Sikka, David A. Silver, Jeffrey H. Silverstein, Emily A. Singer, Ken Solt, Spiro G. Spanakis, Wolfgang Steudel, Matthias Stopfkuchen-Evans, Michael P. Storey, Gary R. Strichartz, Balachundhar Subramaniam, Wariya Sukhupragarn, John Summers, Shine Sun, Eswar Sundar, Sugantha Sundar, Neelakantan Sunder, Faraz Syed, Usha B. Tedrow, Nelson L. Thaemert, George P. Topulos, Lawrence C. Tsen, Richard D. Urman, Charles A. Vacanti, Francis X. Vacanti, Joshua C. Vacanti, Assia Valovska, Ivan T. Valovski, Mary Ann Vann, Susan Vassallo, Anasuya Vasudevan, Kamen V. Vlassakov, Gian Paolo Volpato, Essi M. Vulli, J. Matthias Walz, Jingping Wang, James F. Watkins, Maxwell Weinmann, Sharon L. Wetherall, Mallory Williams, Sarah H. Wiser, Zhiling Xiong, Warren M. Zapol, Jie Zhou
Edited by Charles Vacanti, Scott Segal, Pankaj Sikka, Richard Urman
Book: Essential Clinical Anesthesia
Print publication: 11 July 2011, pp xv-xxviii
Plasma concentrations of 25-hydroxyvitamin D in meat eaters, fish eaters, vegetarians and vegans: results from the EPIC–Oxford study
Francesca L Crowe, Marinka Steur, Naomi E Allen, Paul N Appleby, Ruth C Travis, Timothy J Key
Journal: Public Health Nutrition / Volume 14 / Issue 2 / February 2011
Vegetarians and vegans exclude certain food sources of vitamin D from their diet, but it is not clear to what extent this affects plasma concentrations of 25-hydroxyvitamin D (25(OH)D). The objective was to investigate differences in vitamin D intake and plasma concentrations of 25(OH)D among meat eaters, fish eaters, vegetarians and vegans.
A cross-sectional analysis.
Plasma 25(OH)D concentrations were measured in 2107 white men and women (1388 meat eaters, 210 fish eaters, 420 vegetarians and eighty-nine vegans) aged 20–76 years from the European Prospective Investigation into Cancer and Nutrition (EPIC)–Oxford cohort.
Plasma 25(OH)D concentrations reflected the degree of animal product exclusion and, hence, dietary intake of vitamin D; meat eaters had the highest mean intake of vitamin D (3·1 (95 % CI 3·0, 3·2) μg/d) and mean plasma 25(OH)D concentrations (77·0 (95 % CI 75·4, 78·8) nmol/l) and vegans the lowest (0·7 (95 % CI 0·6, 0·8) μg/d and 55·8 (95 % CI 51·0, 61·0) nmol/l, respectively). The magnitude of difference in 25(OH)D concentrations between meat eaters and vegans was smaller (20 %) among those participants who had a blood sample collected during the summer months (July–September) compared with the winter months (38 %; January–March). The prevalence of low plasma concentrations of 25(OH)D (<25 nmol/l) during the winter and spring ranged from <1 % to 8 % across the diet groups.
Plasma 25(OH)D concentrations were lower in vegetarians and vegans than in meat and fish eaters; diet is an important determinant of plasma 25(OH)D in this British population.
Phytanic acid: measurement of plasma concentrations by gas–liquid chromatography–mass spectrometry analysis and associations with diet and other plasma fatty acids
Naomi E. Allen, Philip B. Grace, Annette Ginn, Ruth C. Travis, Andrew W. Roddam, Paul N. Appleby, Timothy Key
Journal: British Journal of Nutrition / Volume 99 / Issue 3 / March 2008
Epidemiological data suggest that a diet rich in animal foods may be associated with an increased risk of several cancers, including cancers of the prostate, colorectum and breast, but the possible mechanism is unclear. It is hypothesised that phytanic acid, a C20 branched-chain fatty acid found predominantly in foods from ruminant animals, may be involved in early cancer development because it has been shown to up regulate activity of α-methylacyl-coenzyme A racemase, an enzyme commonly found to be over-expressed in tumour cells compared with normal tissue. However, little is known about the distribution of plasma phytanic acid concentrations or its dietary determinants in the general population. The primary aim of the present cross-sectional study was to determine circulating phytanic acid concentrations among ninety-six meat-eating, lacto-ovo-vegetarian and vegan women, aged 20–69 years, recruited into the Oxford component of the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford). Meat-eaters had, on average, a 6.7-fold higher geometric mean plasma phytanic acid concentration than the vegans (5·77 v. 0·86 μmol/l; P < 0·0001) and a 47 % higher mean concentration than the vegetarians (5·77 v. 3·93 μmol/l; P = 0·016). The strongest determinant of plasma phytanic acid concentration appeared to be dairy fat intake (r 0·68; P < 0·0001); phytanic acid levels were not associated with age or other lifestyle factors. These data show that a diet high in fat from dairy products is associated with increased plasma phytanic acid concentration, which may play a role in cancer development.
Calcium, diet and fracture risk: a prospective study of 1898 incident fractures among 34 696 British women and men
Timothy J Key, Paul N Appleby, Elizabeth A Spencer, Andrew W Roddam, Rachel E Neale, Naomi E Allen
Journal: Public Health Nutrition / Volume 10 / Issue 11 / November 2007
The risk factors for fractures are incompletely understood. An outstanding question concerns the optimal amount of dietary calcium needed to minimise the risk of fracture.
We examined the associations of dietary calcium and other nutrients with self-reported fracture risk in a prospective cohort study. Nutrient intakes were estimated using a semi-quantitative food-frequency questionnaire administered at recruitment.
The UK.
A total of 26 749 women and 7947 men aged 20–89 years.
Over an average of 5.2 years of follow-up, 1555 women and 343 men reported one or more fractures, 72% of these resulting from a fall. Among women, fracture risk was higher at lower calcium intakes, with a relative risk of 1.75 (95% confidence interval (CI) 1.33–2.29) among women with a calcium intake of < 525 mg day− 1 compared with women with a calcium intake of at least 1200 mg day− 1 (test for linear trend, P < 0.001). The association of dietary calcium with fracture risk was stronger among women aged under 50 years at recruitment than among women aged 50 and above. Dietary calcium intake was not associated with fracture risk in men. Fracture risk was not related to the dietary intake of any other nutrient examined.
In this population, women with a low dietary calcium intake had an increased risk of bone fracture, and this association was more marked among younger women than among older women.
Diet, nutrition and the prevention of cancer
Timothy J Key, Arthur Schatzkin, Walter C Willett, Naomi E Allen, Elizabeth A Spencer, Ruth C Travis
Journal: Public Health Nutrition / Volume 7 / Issue 1a / February 2004
To assess the epidemiological evidence on diet and cancer and make public health recommendations.
Review of published studies, concentrating on recent systematic reviews, meta-analyses and large prospective studies.
Conclusions and recommendations:
Overweight/obesity increases the risk for cancers of the oesophagus (adenocarcinoma), colorectum, breast (postmenopausal), endometrium and kidney; body weight should be maintained in the body mass index range of 18.5–25?kg/m2, and weight gain in adulthood avoided. Alcohol causes cancers of the oral cavity, pharynx, oesophagus and liver, and a small increase in the risk for breast cancer; if consumed, alcohol intake should not exceed 2?units/d. Aflatoxin in foods causes liver cancer, although its importance in the absence of hepatitis virus infections is not clear; exposure to aflatoxin in foods should be minimised. Chinese-style salted fish increases the risk for nasopharyngeal cancer, particularly if eaten during childhood, and should be eaten only in moderation. Fruits and vegetables probably reduce the risk for cancers of the oral cavity, oesophagus, stomach and colorectum, and diets should include at least 400?g/d of total fruits and vegetables. Preserved meat and red meat probably increase the risk for colorectal cancer; if eaten, consumption of these foods should be moderate. Salt preserved foods and high salt intake probably increase the risk for stomach cancer; overall consumption of salt preserved foods and salt should be moderate. Very hot drinks and foods probably increase the risk for cancers of the oral cavity, pharynx and oesophagus; drinks and foods should not be consumed when they are scalding hot. Physical activity, the main determinant of energy expenditure, reduces the risk for colorectal cancer and probably reduces the risk for breast cancer; regular physical activity should be taken.
EPIC–Oxford:lifestyle characteristics and nutrient intakes in a cohort of 33 883 meat-eaters and 31 546 non meat-eaters in the UK
Gwyneth K Davey, Elizabeth A Spencer, Paul N Appleby, Naomi E Allen, Katherine H Knox, Timothy J Key
Journal: Public Health Nutrition / Volume 6 / Issue 3 / June 2003
To describe the lifestyle characteristics and nutrient intakes of the Oxford cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC).
Cohort of men and women recruited through general practices or by post to include a high proportion of non meat-eaters. Dietary, anthropometric and lifestyle data were collected at baseline and four diet groups were defined.
In total, 65 429 men and women aged 20 to 97 years, comprising 33 883 meat-eaters, 10 110 fish-eaters, 18 840 lacto-ovo vegetarians and 2596 vegans.
Nutrient intakes and lifestyle factors differed across the diet groups, with striking differences between meat-eaters and vegans, and fish-eaters and vegetarians usually having intermediate values. Mean fat intake in each diet group was below the UK dietary reference value of 33% of total energy intake. The mean intake of saturated fatty acids in vegans was approximately 5% of energy, less than half the mean intake among meat-eaters (10–11%). Vegans had the highest intakes of fibre, vitamin B1, folate, vitamin C, vitamin E, magnesium and iron, and the lowest intakes of retinol, vitamin B12, vitamin D, calcium and zinc.
The EPIC–Oxford cohort includes 31 546 non meat-eaters and is one of the largest studies of vegetarians in the world. The average nutrient intakes in the whole cohort are close to those currently recommended for good health. Comparisons of the diet groups show wide ranges in the intakes of major nutrients such as saturated fat and dietary fibre. Such variation should increase the ability of the study to detect associations of diet with major cancers and causes of death.
Soya intake and plasma concentrations of daidzein and genistein: validity of dietary assessment among eighty British women (Oxford arm of the European Prospective Investigation into Cancer and Nutrition)
Pai K. Verkasalo, Paul N. Appleby, Naomi E. Allen, Gwyneth Davey, Herman Adlercreutz, Timothy J. Key
Journal: British Journal of Nutrition / Volume 86 / Issue 3 / September 2001
Soya products contain high levels of the isoflavones genistein and daidzein, and their glucosides, and may lower the risk of cardiovascular disease, osteoporosis and cancer. The present cross-sectional study investigated plasma concentrations of daidzein and genistein and their correlations with dietary soya consumption in four groups of twenty premenopausal British women. The women were selected from the Oxford arm of the European Prospective Investigation into Cancer and Nutrition using data from food-frequency questionnaires (FFQ) to guarantee a wide variation in soya consumption, and to investigate the utility of the question related to soya milk consumption compared with the utility of the question related to other soya foods. Dietary intakes of isoflavones were additionally assessed by 7 d food diaries. Plasma concentrations of daidzein and genistein were measured by time-resolved fluoroimmunoassay. Geometric mean plasma concentrations (nmol/l) were for the four groups, which were based on increasing soya intake, 4·9, 8·4, 39·2 and 132 for daidzein and 14·3, 16·5, 119 and 378 for genistein. The Spearman correlation coefficients for plasma isoflavone concentrations with estimated dietary intakes were between 0·66 and 0·80 for the diary-based estimates and between 0·24 and 0·74 for the FFQ-based estimates. The correlations for soya milk intakes were clearly higher than the correlations for intakes of other soya foods. We conclude that both the food diary and the FFQ estimate dietary soya isoflavone intakes sufficiently well to use them in epidemiological studies, and that plasma concentrations of daidzein and genistein in Western women who consumed soya products as a part of their regular diet were close to those in Asian populations.
Energy balance and cancer: the role of sex hormones
Timothy J. Key, Naomi E. Allen, Pia K. Verkasalo, Emily Banks
Journal: Proceedings of the Nutrition Society / Volume 60 / Issue 1 / February 2001
Energy balance can affect the risk for hormone-related cancers by altering sex hormone levels. Energy intake and expenditure are difficult to measure in epidemiological studies, but a chronic excess of intake relative to expenditure leads to a high BMI, which can be accurately measured. In premenopausal women obesity has little effect on the serum concentration of oestradiol, but causes an increase in the frequency of anovular menstrual cycles and thus a reduction in progesterone levels; these changes lead to a large increase in the risk for endometrial cancer, but little change, or a small decrease, in the risk for breast cancer. In post-menopausal women oestradiol levels are not regulated by negative feedback, and obesity causes an increase in the serum concentration of bioavailable oestradiol; this factor causes increases in the risk for both endometrial cancer and breast cancer. The development of ovarian cancer appears to be related more strongly to the frequency of ovulation than to direct effects of circulating levels of sex hormones, and BMI is not clearly associated with the risk for ovarian cancer. In men, increasing BMI has little effect on bioavailable androgen levels, and any effect of obesity on prostate cancer risk is small.
The effects of diet on circulating sex hormone levels in men
Naomi E Allen, Timothy J Key
Journal: Nutrition Research Reviews / Volume 13 / Issue 2 / December 2000
There is considerable epidemiological evidence that a Western-style diet may increase the risk of certain hormone-dependent conditions in men via its effects on hormone metabolism. Experimental evidence also suggests that dietary factors may exert subtle effects on hormone metabolism. Here we review the clinical and epidemiological evidence that diet is associated with circulating sex hormone levels in men. In comparison with factors such as age and BMI, nutrients do not appear to be strong determinants of sex hormone levels. Dietary intervention studies have not shown that a change in dietary fat and/or dietary fibre intake is associated with changes in circulating sex hormone concentrations over the short term. The data on the effects of dietary phyto-oestrogens on sex hormone levels in men are too limited for conclusions to be drawn. Observational studies between men from different dietary groups have shown that a vegan diet is associated with small but significant increases in sex-hormone-binding globulin and testosterone concentrations in comparison with meat-eaters. However, these studies have not demonstrated that variations in dietary composition have any long-term important effects on circulating bioavailable sex hormone levels in men. This lack of effect may be partly explained by the body's negative feedback mechanism, which balances out small changes in androgen metabolism in order to maintain a constant level of circulating bioavailable androgens. It appears, therefore, that future studies should look for dietary effects on the feedback mechanism itself, or on the metabolism of androgens within the target tissues.


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The Global Shipping Network Is Finally Revealed
Despite carrying 90 percent of the planet's trade, nobody has mapped the network of links between the world's ports. Until now.
Emerging Technology from the arXiv archive page
The International Maritime Organization based in London estimates that 90 percent of the world's trade is moved around the planet by sea. Given the fascination that complexity scientists have with rail, air and road networks, it seems strange that so little attention has been paid to the maritime network.
That's a wrong that's put right today by Pablo Kaluza and pals at Carl von Ossietzky University in Oldenburg, Germany. These guys have used the itineraries of 16,363 cargo ships during 2007 to construct a network of links between the world's top 951 ports. The results, at least in part, are eyebrow raising.
First, the unsurprising news. Kaluza and co show that these links form a small world network in which it is easy to move from one port to another in a small number of jumps. That's just what you'd expect given what we know about other transport networks.
However, the maritime network shows some surprising differences from the network that flight paths make between airports. For example, on average, it takes just 2.5 jumps to move from one port to another on the maritime network compared to an average of 4.4 to move between one airport and another. The maximum shortest path between ports is 8 jumps while between airports it is 15 jumps. It looks to be decidedly easier to travel the world by ship than by plane, at least in some respects.
One oddity, however, is that the maritime network is decidedly asymmetric: more than half of all ports are linked in only one direction, meaning that cargo ships do not routinely make round trip journeys between ports.
Perhaps most interesting of all is that different types of ship move in different patterns. Kaluza and co study three types of ship: container ships, bulk dry carriers and oil tankers. While container ships tend to follow regular schedules, the movement of bulk dry carriers and oil tankers is much less regular. That's because their routes are determined by the price of the commodities they carry and which vary enormously. Bulk dry carriers and oil tankers are also more likely to sail empty.
That's important because it gives a unique insight into the pattern of world trade. But there is another reason too.
One of the most significant methods of cross species invasion is from water sucked into ships' ballast tanks in one part of the world and discharged in another; a particularly important factor when ships sail empty.
So the new network map should give marine biologists an insight into how bioinvasion occurs and what steps they can take to tackle it.
Emerging Technology from the arXiv


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Tim Cook Speaks at University of Glasgow for an Hour (Video)
Bryan Chaffin
Feb 9th, 2017 7:46 PM EST | Cool Stuff Found
Tim Cook spoke to the students of the University of Glasgow this week. The hour long event included questions from faculty and students alike. Topics included President Trump's travel bans on seven muslim-majority countries, the reach of the App Store, the environment, wealth inequality, education, balancing work and life, technology interacting with our bodies, Apple Watch, idealism, Steve Jobs's influence over Apple today, styluses, and more. The video was posted by a student. The audio quality is poor, but the rules for the event precluded "dedicated recording equipment." To that end, this video was recorded entirely on an iPhone 7 in the hands of a student 50-70 feet from Mr. Cook, and is stunningly good considering. In addition, note how quiet and respectful this audience of 800-plus students is.
Check It Out: Tim Cook Speaks at University of Glasgow for an Hour (Video)
Donald Trump Steve Jobs Tim Cook
Pinterest Visual Search Gets A Tool Called Lens
Steve Jobs NeXT Keynote in 1992 Is a Must-Watch for Jobs Fans [Update]
cool-stuff-found


Today I fasted for the climate. I fasted in solidarity with people who are losing their lives and livelihoods to climate change, and with those who are dedicating every ounce of themselves to fighting it.
Climate change is going to bring hungry days to the world, more than we're prepared to cope with. Most fundamentally, it will amplify food insecurity through desertification, sea level rise, and extreme weather. Food prices will rise, and people and families teetering on the edge of poverty will be pushed further from opportunity. And the same populations who already couldn't afford food will disproportionately lose their livelihoods to the same disaster. People with resources put carbon into the air, and those without starve.
Yet I went 8,337 days in the world without knowing what 24 hours of hunger felt like. Many go their whole lives without knowing even that much.
Guilt is an easy emotion in this situation, easy enough to have been overused by a thousand campaigns, easy enough to have gone stale. Guilt is too draining to be spent on remote problems, and besides, it's easy to think, what am I supposed to do, starve myself?
We're born into a social system that was off running before humans were humans. Hard resets won't work on such a beast, not when its inertia is so splintered and old. To alter such a system, we need to tweak that inertia wherever it lies, in countless human minds and centers of power.
So when you ask why fasting matters, how such a small and personal action could have any discernible effect on the world, there are two answers.
First, no offense, but you're awfully small and indiscernible yourself. If you're reading this, you almost definitely don't wield a great deal of power. It's very possible that no single decision you ever make will have a discernible effect on the world. And that doesn't matter. The issue at hand is how you exist in the world, the effort you make to take the inertia of your upbringing and redirect it towards justice. Each decision is a fraction of a degree adjustment in our system's inertia, but each fraction is a fraction more than none.
Second and always is solidarity. Fasting for a day will not tell you what it is like to weekly choose your family's foodless days. It will pose the question, and as you process its effects, as you spread the idea, you'll remember more often the humans it's too easy to ignore.
Our inertia will change, and you won't notice. No one will.


Pennsylvania has a long history of high medical malpractice premiums. Many attempts have been made to reform the Quaker State's medical liability system; some have been more successful than others. In the early 1970s, Pennsylvania faced the same malpractice crisis that was affecting many U.S. states. Premiums were skyrocketing, and the commonwealth's then-largest medical liability insurer, Argonaut, threatened to stop writing policies altogether. In 1975, Argonaut sought to increase premiums by 200 percent for many specialties. In response, the Pennsylvania Medical Society and General Assembly worked together to pass the Health Care Services Malpractice Act (Act 111) of 1975, becoming one of the first states to pass wide-ranging legislative reforms in response to the medical liability crisis gripping the country. The act created the Medical Professional Catastrophic Loss (CAT) Fund. The CAT Fund was the United States' first public patient compensation fund (PCF), a state-established liability-funding instrument that provides medical professional liability coverage in excess of a physician's primary insurance limits. Several other provisions to restrict attorney fees, mandate arbitration panels and establish a collateral source rule were also included, but these were found to be unconstitutional by the Pennsylvania Supreme Court.
Pennsylvania has continued to reform its medical liability system since Act 111 was passed. In 1996, legislation limiting punitive damages to $100,000 was passed, CAT Fund surcharges were reduced, physicians were allowed to provide affidavits of non-involvement, meaning that they could swear under oath that they were not involved in a case and be cleared of wrongdoing and a four-year moratorium was placed on further medical liability legislation. However, difficulties in the Pennsylvania market continued, with three of the five major malpractice insurers in the state ceasing to write in Pennsylvania by the early 2000s. In response, the Medical Care Availability & Reduction of Error Act (Mcare) was passed in 2002. Its reforms were comprehensive, addressing both medical errors in the healthcare system and reforms to the legal system and the medical malpractice industry.
The Mcare Act sought to emphasize patient safety and reduce medical errors, creating a Patient Safety Authority and requiring all hospitals to incorporate detailed patient safety plans. It also included a range of legal reforms to restrict frivolous law suits by instituting stronger expert witness qualifications and sanctioning lawyers who brought frivolous claims. Additionally, Mcare restructured the states CATFund, renaming it the Mcare Fund and equipping it with $400 million in state subsidies to reduce physician assessments. It also increased assessments for doctors with excessive claims and required insurers to offer patient-safety discounts and credits.
In 2018, the Pennsylvania Supreme Court made a decision that has significantly changed the scope of what is available in the discovery process for medical liability lawsuits, making it easier for plaintiffs to obtain materials related to physician performance and credentials. These materials were previously considered protected from discovery by the commonwealth's Peer Review Protection Act (PRPA), which gave increased protection to healthcare professionals and review panel evaluations of physician performance that investigate possible malpractice incidences. The PRPA considered materials that are prepared as part of a peer review process privileged and protected from discovery. However, in the 2018 decision of Reginelli v. Boggs, the Pennsylvania Supreme Court held that the PRPA does not extend protection from disclosure to a non-licensed, third-party entity or committees or individuals reviewing physician credentials. The Pennsylvania Supreme Court found the protective privilege of the PRPA did not apply to Bogg's "performance file," which was authored by his supervising doctor at the hospital. The court came to this conclusion because the hospital itself was not "approved, licensed or otherwise regulated to practice or operate in the healthcare field under the laws of the Commonwealth," and because the performance file was a review of Boggs's credentials, which does not fall within the PRPA's evidentiary privilege. This holding has the potential to have widespread effects on the materials that are discoverable and likely opens the door for plaintiffs to seek additional reports and files during discovery.
Tort reform has been carried out many times in the Quaker State, including the establishment of the first patient compensation fund in the United States, known as the CAT Fund and later reformulated as the Mcare Fund. However, Pennsylvania has been unsuccessful in creating damage caps, which are often considered the 'holy grail' of medical liability reform. Though many important provisions have been made to improve the medical liability system, physicians still face high rates throughout the state.
Currently, all Pennsylvania physicians are required to participate in Mcare. Physicians are legally required to maintain limits of $1 million/$3 million, with a primary private policy of $500,000/$1.5 million. The rest of the coverage is provided through Mcare, which provides up to an additional $500,000 of excess coverage per claim. Physicians must pay into the Mcare Fund, but it is generally less expensive than private policies. By state law, Pennsylvania must reevaluate the Mcare Fund every two years, with the plan of eventually closing the fund. This will be done gradually, with private insurers retaining more and more of the $1 million limit until they eventually reach 100 percent.
Damage Caps? Yes, but only for punitive damages. Noneconomic damage caps have been ruled to be unconstitutional by the Pennsylvania Supreme Court.
Apology Law? Yes, actions, conduct, statements or gestures that convey a sense of apology, condolence, explanation, compassion or commiseration emanating from humane impulses can be made to a patient or a patient's relative or representative.
Joint Liability Reform? Yes, defendants who are less than 60 percent at fault are liable only for their portion of fault, except in cases of intentional misrepresentation or intentional tort. Defendants found to be 60 percent or more at fault are jointly and severally liable.
Rates in Pennsylvania are high, with many surgeons paying well over $50,000 per year in premium. Specialists like OBGYNs frequently face premiums of well over $100,000, depending on their location and the procedures they do. Rates for general practitioners can range up to $30,000, but are generally in the $12,000 – $25,000 range, depending on location. Rates have fallen for some specialties and in some locations in recent years, but medical liability costs still remain a major concern for Pennsylvania physicians.
By combining our efforts with those of the Medical Liability Monitor – the nation's leading independent source of Medical Liability Insurance news, as well as the political, legal and risk management issues that affect the healthcare industry – we've published historic rate data for every county in the Quaker State. You can view all the rates by completing the three simple steps on the left of this page. You'll find the insights offered by this information invaluable when making your decision on your medical malpractice insurance coverage and carriers. This is only one of the many reasons that Cunningham Group Insurance has become the preferred online source for Pennsylvania physicians, healthcare professionals and medical groups looking to find the best coverage and lower their medical malpractice insurance rates.
The highest rates in Pennsylvania are generally found in Philadelphia and Delaware Counties, which include Philadelphia and the surrounding areas. In general, counties in the eastern part of the state tend to have more expensive premiums than those in Western Pennsylvania. For example, Alleghany County, which includes the city of Pittsburgh, has substantially lower malpractice premiums than eastern parts of the state.


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Vidya Academy of Science and Technology Technical Campus (VAST TC), is a privately financed engineering college in Thiruvananthapuram District in Kerala situated at Kilimanoor.The college offers a degree in Bachelor of Technology and courses in five branches of engineering -  Civil, Computer Science, Electrical and Electronics, Electronics and Communication, Mechanical.
The college was established and is administered by Vidya International Charitable Trust (VICT), a body formed by more than a thousand non-resident Keralites mostly based in the Arab States of the Persian Gulf.

Vidya Academy of Science and Technology Technical Campus is accredited by NAAC with "B++" Grade in 2022.

See also
 Vidya Academy of Science and Technology, Thrissur

References

External links
 Vidya Academy Kilimanoor, Official Website
 Vidya International Charitable Trust, Official Website

All India Council for Technical Education
Engineering colleges in Thiruvananthapuram
Private engineering colleges in Kerala
Vidya Academy of Science and Technology