Raymond Dalio is an American investor, hedge fund manager and philanthropist. Dalio is the founder of investment firm Bridgewater Associates, one of the world's largest hedge funds.
LARGEST FUNDS IN THE WORLD WITH TRILLIONS! 2017?
World's Biggest Hedge Fund Just Bet $22 Billion That the EU Is Going To COLLAPSE!
Sovereign Wealth Funds control over $7 trillion worth of assets and have become a significant feature of the global economic landscape. In this short revision video we identify countries with sovereign wealth funds and some of the investments they have been making.
Follow Dan's guide to stock buys & sells: https://www.financialissues.org Listen to Dan Live every day at https://www.financialissues.org Like Dan on Facebook: https://www.facebook.com/financialissues Follow Dan on Twitter: https://twitter.com/financialissues Financial Issues - Program September 19, 2017 *Information given by Dan could be based upon time sensitive market data or economic situations that are subject to change.
World's biggest Sovereign wealth fund. Vision TV World.
Sovereign wealth fund of Norway is the largest in the world; on 19th September, 2017 it reached the value of USD 1 trillion for the first time. Vision TV World.
The pioneers of the hedge-fund industry changed Wall Street. By placing at times brilliant bets in the market they gained considerable personal wealth, but according to New Yorker staff writer Sheelah Kolhatkar, an outsize influence on society too. She joins The Agenda to discuss the seven-year investigation into Steven A. Cohen, one of the industry's biggest success stories, and her book, "The Black Edge: Inside Information, Dirty Money, and the Quest to Bring Down the Most Wanted Man on Wall Street."
What is a Hedge Fund? How Do Hedge Funds Work? - Please take a moment to Like, Subscribe, and Comment on this video! View Our Channel To See More Helpful Finance Videos - https://www.youtube.com/user/FinanceWisdomForYou etf mutual funds venture capital index funds investment banking mutual fund trust fund investment hedge angel investors asset management investments what is a hedge fund investors best mutual funds hedge funds hedging investor exchange traded funds fund venture capital firms money market funds investment companies hedge fund definition hedge fund manager investment management funds hedge fund jobs soros fund management top mutual funds mutual fund definition alternative investments investment banks investment firms investment strategies hedge fund manager salary mutual fund companies fund of funds top hedge funds pension fund hedgefund how to start a hedge fund what are hedge funds managed futures investment company sovereign wealth funds how to become a hedge fund manager bridgewater hedge fund 100 women in hedge funds what is hedge fund largest hedge funds hedge fund news what is hedging define hedge fund hedge fund salary starting a hedge fund hedge fund analyst salary top hedge fund managers hedge fund alert fund manager managed funds association asset management companies hedge fund research investment funds investment manager best hedge funds hedge fund analyst hedge fund strategies hedge fund managers equity fund investment fund alternative investment what is a hedge fund manager hedge fund companies biggest hedge funds hedge fund internships paulson hedge fund fund management hedge fund association list of hedge funds mutual funds performance hedge fund performance equity funds hedgefunds etf mutual funds venture capital index funds investment banking mutual fund trust fund investment hedge angel investors asset management investments what is a hedge fund investors best mutual funds hedge funds hedging investor exchange traded funds fund venture capital firms money market funds investment companies hedge fund definition hedge fund manager investment management funds hedge fund jobs soros fund management top mutual funds mutual fund definition alternative investments investment banks investment firms investment strategies hedge fund manager salary mutual fund companies fund of funds top hedge funds pension fund hedgefund how to start a hedge fund what are hedge funds managed futures investment company sovereign wealth funds how to become a hedge fund manager bridgewater hedge fund 100 women in hedge funds what is hedge fund largest hedge funds hedge fund news what is hedging define hedge fund hedge fund salary starting a hedge fund hedge fund analyst salary top hedge fund managers hedge fund alert fund manager managed funds association asset management companies hedge fund research investment funds investment manager best hedge funds hedge fund analyst hedge fund strategies hedge fund managers equity fund investment fund alternative investment what is a hedge fund manager hedge fund companies biggest hedge funds hedge fund internships paulson hedge fund fund management hedge fund association list of hedge funds mutual funds performance hedge fund performance equity funds hedgefunds What is a Hedge Fund? How Do Hedge Funds Work? First, hedge funds are not currently regulated by the U.S. Securities and Exchange Commission (SEC), a financial industry oversight entity, as mutual funds are. However, it appears that regulation for hedge funds may be coming soon. Second, as a result of being relatively unregulated, hedge funds can invest in a wider range of securities than mutual funds can. While many hedge funds do invest in traditional securities, such as stocks, bonds, commodities and real estate, they are best known for using more sophisticated (and risky) investments and techniques. What is a Hedge Fund? How Do Hedge Funds Work? First, hedge funds are not currently regulated by the U.S. Securities and Exchange Commission (SEC), a financial industry oversight entity, as mutual funds are. However, it appears that regulation for hedge funds may be coming soon. Second, as a result of being relatively unregulated, hedge funds can invest in a wider range of securities than mutual funds can. While many hedge funds do invest in traditional securities, such as stocks, bonds, commodities and real estate, they are best known for using more sophisticated (and risky) investments and techniques. Finance Wisdom For You Finance Wisdom For You What is a Hedge Fund? How Do Hedge Funds Work?
What is ABU DHABI INVESTMENT AUTHORITY? What does ABU DHABI INVESTMENT AUTHORITY mean?
What is ABU DHABI INVESTMENT AUTHORITY? What does ABU DHABI INVESTMENT AUTHORITY mean? ABU DHABI INVESTMENT AUTHORITY meaning - ABU DHABI INVESTMENT AUTHORITY definition - ABU DHABI INVESTMENT AUTHORITY explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license. The Abu Dhabi Investment Authority (ADIA) is a sovereign wealth fund owned by Emirate of Abu Dhabi (in United Arab Emirates) founded for the purpose of investing funds on behalf of the Government of the Emirate of Abu Dhabi. It manages the Emirate's excess oil reserves, estimated to be as much as $500 billion. Its portfolio grows at an annual rate of about 10% compounded. The fund is a member of the International Forum of Sovereign Wealth Funds and is therefore signed up to the Santiago Principles on best practice in managing sovereign wealth funds. ADIA has never published how much it has in assets but estimates have been between $800 billion to approximately $875 billion USD. The Sovereign Wealth Fund Institute puts the figure at US$792 billion. In 1967, Abu Dhabi emirate created the Financial Investments Board which operated within its Department of Finance and was responsible for managing the Emirate's excess oil revenues. However, in 1976, Sheikh Zayed bin Sultan Al Nahyan, the founding President of the United Arab Emirates and leader of Abu Dhabi made the decision to create the Abu Dhabi Investment Authority instead and separate it from the government as an arms-length organization with its own management. The goal was to invest the Abu Dhabi government's surpluses across various asset classes, with low risk. At the time it was novel for a government to invest its reserves in anything other than gold or short-term credit. Even today, investment in short-term paper remains the strategy for the vast majority of countries. ADIA manages a substantial amount of capital, and is one of the world's largest investment funds. Due to its size, the fund has been influential in international finance. In 2008, ADIA co-chaired the International Working Group of 26 sovereign wealth funds that produced the "Generally Accepted Principles and Practices of sovereign wealth funds" (known as the Santiago Principles). These principles were created to demonstrate to home and recipient countries and the international financial markets that sovereign wealth funds had robust internal frameworks and governance practices and that their investments were made only on an economic and financial basis. 20-year and 30-year annualized rates of return for the ADIA portfolio were 7.6% and 8.1%, respectively, as of 31 December 2010. ADIA is one of the largest sovereign wealth funds in the world. Today ADIA invests in all the international markets – equities, fixed income and treasury, infrastructure, real estate, private equity and alternatives (hedge funds and commodity trading advisers – CTAs). ADIA's global portfolio is broken down into sub-funds covering a specific asset class. Each asset class has its own fund managers and in-house analysts covering it. Almost every asset class is managed both internally and externally. Overall between 70% and 80% of the organization's assets are managed outside, and over the last few years the fund has become more indexed which given its unique asset liability structure is somewhat perplexing. The Abu Dhabi Investment Authority (ADIA) is a major purchaser of U.S. institutional real estate through various sub-entities. It often buys partial interest ownerships with leading real estate managers. ADIA also invests in development projects including malls. Many of ADIA's investments have decreased substantially since investments were made at market peaks in 2007 and 2008. The $7 billion investment in Citigroup has lost approximately 90% of its value as of 26 Nov 2009, 2 years after it acquired a sizable stake in the bank. Its investments in global real-estate at the market top in 2008 have also decreased substantially in value. Though it talks of its long term success in generating returns, the fact that it has moved closer to the index and manages most of its funds through external third party fund managers shows that its tolerance for risk taking is greatly diminished over the years. However, ADIA's ratio of third-party fund managers is being actively managed. In 2006, between 70% and 80% of the organization's assets were managed outside with an aim to bring that down to between 60% and 70%. On 27 May 2013, ADIA published its 2012 Review, with an overview of its activities during the past year as well as an explanation of its approach to investing – strategy, governance and risk management.
With more than EUR 4,200 billion in net assets under management, Luxembourg is the largest investment fund centre in Europe and the second largest in the world after the US. It is the largest global distribution centre for investment funds, with its funds offered in more than 70 countries around the world.
http://www.interest.co.nz/ratesblog Welcome to interest.co.nz's morning briefing of what's news here and around the world. Everything you need to start the day in 90 seconds at 9'oclock.... Starting now With news overnight of more credit crunch trouble in the shadowey world of hedge funds. Drake Capital Management shut its biggest hedge fund while another hedge fund GO Capital Asset Management closed one of its funds to cash withdrawals. This all follows the surprise move, which was reported first on interest.co.nz, that ING NZ had shut two of its funds to withdrawals after a run on the funds. Both of the funds invested in collateralized debt obligations and collateralized loan obligations. These CDOs and CLOs are now short hand for toxic bonds. Meanwhile after initial eurphoria, investors are now having second thoughts about the Federal Reserve's move pump US$200 billion of liquidity into the markets. They are wondering if it is enough to calm nerves in the market. One to watch. More nervous markets mean higher interest rates and in the short term, a lower currency. And finally news from home that house prices fell again in February. They are now down more than 4% from their peak in November. The real estate agents institute is now worried about annual price deflation and has warned the government of the economic and political fallout from falling prices. That was 90 seconds at 9 o'clock. I'm Bernard Hickey for interest.co.nz.
Gregor Zupanc (Co-founder & CEO of Solidum Capital) explains where the enormous profits of the greatest hedge fund managers actually come from. Prefer to read this? https://solidum.capital/blog/how-top-hedge-fund-managers-earn-billions-dollars-each-year ••• SOLIDUM CAPITAL is a digital asset management company for the crypto community. Their world-class crypto portfolios provide simple access to the most perspective global crypto. The team consists of experienced professionals with over 15 years of experience in the traditional fund management industry, private equity, strategic consulting, and information technology. The team firmly believes in the long-term potential of blockchain technology, and their goal is to educate people about the potential of this technology and crypto investments as such. FOLLOW Solidum Capital crypto news, insights, and debates here: • Website: https://www.solidum.capital • Twitter: https://twitter.com/SolidumCapital • Facebook: https://www.facebook.com/SolidumCapital • Telegram: https://t.me/SolidumCapital • Medium: https://blog.solidum.capital • LinkedIn: https://www.linkedin.com/company/soli... Subscribe to our WEEKLY NEWSLETTER and get recaps of crypto news, investment insights, ICO and coin analysis, and much more: https://bit.ly/2shZ01A. ••• Solidum Capital also manages the SOLIDUM PRIME CRYPTO FUND (SOPR Digital Portfolio) on the ICONOMI platform: https://my.iconomi.net/asset/SOPR ••• DISCLAIMER This video is for informational and discussion purposes only and does not constitute a marketing message, an investment survey, an investment recommendation, or investment advice. Please do your own research before making any investment decisions. Cryptocurrency investments are highly volatile and risky in nature. Don't invest more than what you can afford to lose. Solidum Capital makes no representations, warranties, or assurances as to the accuracy, currency or completeness of the content contained in this video or any sites linked to or from this video.
Our 'Hedge Funds Tool' allows you to see how leading fund managers have adjusted their positions on the world's leading stocks over the previous fiscal quarter. Frazer Campbell, Head of Client Experience, explains how to use it to your advantage in this video. *76.6% of retail investor accounts lose money when trading CFDs with this provider. You should consider whether you can afford to take the high risk of losing your money.
Subscribe to this channel: http://www.youtube.com/OpalesqueTV Richard Kommel, Morne Marais, and Rob Oellermann set up Tantalum Capital in 2005, having worked together since 1997. Their flagship fund, the Tantalum MNC Fund, has achieved an annual return of 12.6% net since inception in June 2005. Tantalum has recently launched a Global Resources Fund that invests into resources equities and commodities. In this Opalesque.TV portrait, Rob talks about his funds and the attraction of the South African market, offering: - Access to frontier markets in Africa - Extended opportunities in consumer markets - Evolved financial markets He also talks about Tantalum's investment process and background on the team's remarkable high hit ratio in their stock picks and investments. Tantalum Capital commenced operations on 1 June 2005. The business was founded on the shared strategy of the three owners Morne Marais, Richard Kommel and Rob Oellermann as a focused investment management company, managing funds that are closely aligned with their own investment objectives. Robert Oellermann, CA (SA), CFA, started his career in 1994 as quantitative and fundamental equity analyst at Allan Gray Limited. From 1997 until co-founding Tantalum Capital in 2005, Rob was analyst, portfolio manager and Head of Research at Coronation Fund Managers (CFM). Initially, he was co-manager and then manager of the Coronation Consumer Growth Fund. He spent eighteen months in the Dublin and London offices of CFM, analysing European equities and managing the Coronation European Growth Fund. After his return to the Cape Town office of CFM in 2001 he was appointed as Head of Research, managed Coronation's segregated institutional balanced portfolios and eventually direct portfolio manager for institutional equity mandates totaling R7bn.


text:
Home Capital Raising
Blockchain secured voting platform Voatz raises $7 million
Published by CryptoNinjas.net
Voatz, a mobile voting and citizen engagement platform, announced today that it has raised $7 million in Series A funding led by Medici Ventures and Techstars with participation from Urban Innovation Fund and Oakhouse Partners.
The Voatz platform uses biometrics, encryption and blockchain technology to increase convenience, security, and auditability to election systems.
The company plans to leverage the funds to enhance the accessibility and usability of its technology, and to grow its security footprint as it launches new pilot programs with states, cities and select international jurisdictions.
In addition to the pilot programs with Denver and West Virginia, Voatz has partnered with state political parties, universities, labor unions, church groups and nonprofits to administer elections using its platform.
In March 2019, the company announced a new pilot program with the City and County of Denver, CO to expand absentee voting for deployed military personnel and overseas US citizens during the city's 2019 municipal elections, which concluded successfully earlier this week.
Last year, Voatz also conducted a successful pilot with 24 counties in West Virginia during the 2018 Midterm Elections where deployed military personnel and overseas US citizens leveraged the platform to cast their ballots. This pilot represented the first time that mobile voting secured by a blockchain-based infrastructure had ever been used in a US Federal Election.
"We are delighted and grateful for the continued support of our existing and new investors to help us accelerate the development and deployment of our technology. We are committed to the steady progress of mobile voting backed by blockchain technology to improve our election infrastructure and make remote voting more accessible and safer."
Voatz Co-Founder & CEO Nimit Sawhney
"Voting is a great application of blockchain technology. What Voatz is doing to allow more registered voters to participate remotely in elections in a safe and secure way is important. It bodes well for more widespread adoption of the Voatz application. That's one reason we've increased our investment in the company by leading this Series A round."
Medici Ventures President Jonathan Johnson
"Techstars has been impressed with the vision and drive demonstrated by the Voatz team since their participation in the Techstars Boston Accelerator in 2017. We are thrilled to continue to support Voatz on their mission to modernize the technology of voting and to improve the voting experience for constituents around the world."
Techstars Partner Cody Simms
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Blockchain voting platform Voatz participates in U.S. Census Bureau's technology demo day
Voatz, a mobile-focused voting and citizen engagement platform, announced today that it participated in the U.S. Census Bureau's technology Demo Day. The company, which raised $7 million this past summer, demonstrated how the U.S....
Techstars and Alchemist introduce inaugural class of blockchain startup accelerator
Techstars, a worldwide network that helps entrepreneurs succeed, and blockchain advisory firm Alchemist, have announced the inaugural class of their 13-week Alchemist Blockchain Techstars Accelerator, which will be hosted in New York. With a...
Crypto social network Minds.com receives $6 million investment from Medici Ventures
Minds.com, an open-source crypto social network has announced a $6 million Series A investment from Medici Ventures, the wholly-owned blockchain subsidiary of Overstock.com. Founder and CEO of Overstock.com Patrick M. Byrne, a vocal advocate for blockchain,...
Registration opens for NYC blockchain accelerator program by Alchemist and Techstars
Today, applications for the Alchemist Blockchain Techstars Accelerator officially opened, the program will start in February 2019. Alchemist Group, a full-service blockchain advisory firm specializing in token sales and product development of blockchain apps formed...

redpajama_set_name: RedPajamaCommonCrawl


ely easy to use for sharing messages, photos and more, but a child may have difficulty understanding the complexity of Google Buzz's privacy settings. Here's a brief explanation of how one blogger found that out the hard way, and what you can do to keep your child's online life safer.
re using Google Buzz. Li's daughter had sent out an innocuous message via Buzz, but it came as a shock to Li since she didn't realize her daughter was even using Google's new social media tool. Of even more concern for Li was the fact that the sharing control for that message had been set to public, meaning anyone who was following her daughter, or could find her Google profile, would see it.
After further investigation, Li discovered that many of her daughter's friends were also sharing messages with the public, and had even started revealing personal details, such as their e-mail addresses, with complete strangers. Li also found that some less than desirable Google Buzz accounts, such as 'iorgyinbathrooms,' were included among her daughter's Buzz followers.
Now, it should be pointed out that, officially, Google does not allow anyone under the age of 13 to own a Gmail address. However, as Li points out, the age requirement is easily bypassed since Google doesn't even ask for your age when your sign up for Gmail. Li believes it's time for Google to institute some proper parental controls into Gmail.
Microsoft has an Internet safety suite called Family Essentials that you can use to filter and monitor your child's online activity.
tacts lists to decide who your children can communicate with on Windows Live Spaces, Hotmail, and Messenger. The software can also provide detailed activity reports of your child's online activities.
Family Essentials must be installed on every computer your child uses, but you can adjust the privacy and restriction settings online. Family Safety requires Windows XP, Vista, or Windows 7 -- you can find a complete list of system requirements on Windows Live.
AOL has a variety of preset parental controls through its KOL service, with age-specific restrictions for kids 12 and under, 13-15, and 16-17.
You can also set time limits for online access, and get reports on your child's online activities. For AOL's services you have to download Parental Controls software (Windows Only) for Internet Explorer or Firefox, and at time of sign up you will need to provide a credit card for age verification purposes.
specific contacts only; filter e-mail messages with coarse language; remove attachments from incoming mail; and blacklist senders.
Zoo-buh even has something called Mail Queue, which allows you to approve all incoming messages for your child's account before they receive it. Zoo-buh costs $30 per year for each e-mail account.
and Import.' Under 'Send mail as' click 'Send mail from another address' and fill out the pop-up window with your child's name and your child's Gmail address. Google will then send a verification ID to your child's account; once you've verified the e-mail address your child will be able to send e-mail from her or his Gmail account right from your inbox. Next go into your child's Gmail settings, click on 'Forwarding and POP/IMAP' and select 'Forward a copy of incoming mail to' and enter your own Gmail address. You can also choose whether you want to keep a copy of all Gmail messages in that inbox or delete them once they've been forwarded.
Now, your child can send and receive e-mail from your inbox, and you'll see everything that's coming into their account. You can also set up a filter for incoming messages from your child's Gmail address, so your child can see all messages in one spot. One word of warning with this set-up, though: make sure that when your children send e-mail, the child's Gmail account is selected as the "From" account in the compose message window. Otherwise, they may end up sending messages to their friends under your name.
Of course, another alternative is to disable Google Buzz on your child's account by clicking on "Settings" and then "Buzz" and selecting "Disable Google Buzz." This will remove your child's Google profile, Buzz posts, and Buzz followers, and also remove any sites connected to the Google profile such as Facebook and MySpace profiles.


The Healthplex Heart Hospital's Cardiac Rehabilitation Program is one of the few programs in Oklahoma that has achieved certification from the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR). This honor is awarded to programs that demonstrate the highest standards of care and positive outcomes for their patients.
It is our passion and privlege to help improve your health and well-being.
For more information, please contact our Outpatient Cardiac Rehab Program at 405-307-1728.


text:
U.S. intel chief thinking 'optimistically' for Ukraine forces
A house burns after a Russian attack in Kherson, Ukraine, Saturday, Dec. 3, 2022. (AP Photo/Evgeniy Maloletka)
Jamey Keaten and Nomaan Merchant, The Associated Press
Published Sunday, December 4, 2022 6:46PM EST
KYIV, Ukraine (AP) — The head of U.S. intelligence says fighting in Russia's war in Ukraine is running at a "reduced tempo" and suggests Ukrainian forces could have brighter prospects in coming months.
Avril Haines alluded to past allegations by some that Russian President Vladimir Putin's advisers could be shielding him from bad news — for Russia — about war developments, and said he "is becoming more informed of the challenges that the military faces in Russia."
"But it's still not clear to us that he has a full picture of at this stage of just how challenged they are," Haines, the U.S. director of national intelligence, said Saturday at the Reagan National Defense Forum in Simi Valley, California.
She said her team was "seeing a kind of a reduced tempo already of the conflict" and looking ahead expects both sides will look to refit, resupply, and reconstitute for a possible Ukrainian counter-offensive in the spring.
"But we actually have a fair amount of skepticism as to whether or not the Russians will be in fact prepared to do that," said Haines, speaking to NBC's Andrea Mitchell. "And I think more optimistically for the Ukrainians in that time frame."
On Sunday, the British Ministry of Defense, in its latest intelligence estimate, pointed to new signs from an independent Russian media outlet that public support in Russia for the military campaign was "falling significantly."
Meduza said it obtained a recent confidential opinion survey conducted by the Federal Protection Service, which is in charge of guarding the Kremlin and providing security to top government officials.
The survey, commissioned by the Kremlin, found that 55% of respondents backed peace talks with Ukraine while 25% wanted the war to go on. The report didn't mention the margin of error.
Levada Center, Russia's top independent pollster, found in a similar poll carried out in November that 53% of respondents supported peace talks, 41% spoke in favor of continuing the fight, and 6% were undecided. It said that poll of 1,600 people had a margin of error of no more than 3.4%.
The British Defense Ministry noted that "despite the Russian authorities' efforts to enforce pervasive control of the information environment, the conflict has become increasingly tangible for many Russians" since Putin in September ordered a "partial mobilization" of reservists to bolster his forces in Ukraine.
"With Russia unlikely to achieve major battlefield successes in the next several months, maintaining even tacit approval of the war amongst the population is likely to be increasingly difficult for the Kremlin," the British ministry said.
In recent weeks, Russia's military focus has been on striking Ukrainian infrastructure nationwide, pressing an offensive in the Donetsk region city of Bakhmut and shelling sites in the city of Kherson, which Ukrainian forces liberated last month after an 8-month Russian occupation.
In his nightly address on Saturday, Ukrainian President Volodymyr Zelenskyy lashed out at Western efforts to crimp Russia's crucial oil industry, a key source of funds for Putin's war machine, saying their $60-per-barrel price cap on imports of most Russian oil was insufficient.
"It is not a serious decision to set such a limit for Russian prices, which is quite comfortable for the budget of the terrorist state," Zelenskyy said, referring to Russia. He said the $60-per-barrel level would still allow Russia to bring in $100 billion in revenues per year.
"This money will go not only to the war and not only to further sponsorship by Russia of other terrorist regimes and organisations. This money will be used for further destabilisation of those countries that are now trying to avoid serious decisions," Zelenskyy said.
Australia, Britain, Canada, Japan, the United States and the 27-nation European Union agreed Friday to cap what they would pay for Russian oil at $60 per barrel. The limit is set to take effect Monday, along with an EU embargo on Russian oil shipped by sea.
Russian authorities have rejected the price cap and threatened Saturday to stop supplying the nations that endorsed it.
"We will sell oil and oil products to those countries, which will work with us on market conditions, even if we have to somewhat cut production," Deputy Prime Minister Alexander Novak said Sunday.
In yet another show of Western support for Ukraine's efforts to battle back Russian forces and cope with fallout from the war, U.S. Under Secretary of State for Political Affairs Victoria Nuland on Saturday visited the operations of a Ukrainian aid group that provides support for internally displaced people in Ukraine, among her other visits with top Ukrainian officials.
Nuland assembled dolls out of yarn in the blue-and-yellow colors of Ukraine's flag with youngsters from regions including Kharkiv in the northeast, Kherson in the south and Donetsk in the east.
"This is psychological support for them at an absolutely crucial time," Nuland said.
"As President Putin knows best, this war could stop today, if he chose to stop it and withdrew his forces — and then negotiations can begin," she added.
Merchant reported from Washington.
Russia rejects pullout from Ukraine as condition for talks
Ukraine says animals' eyes sent to some of its embassies
G-7 joins EU on $60-per-barrel price cap on Russian oil
Russia rejects $60-a-barrel cap on its oil, warns of cutoffs
No OPEC+ oil shakeup as Russian price cap stirs uncertainty
Ukrainian servicemen walk on a pontoon bridge across the Inhulets river in Kherson region, Ukraine, Saturday, Dec. 3, 2022. (AP Photo/Evgeniy Maloletka)
Avril Haines, Director of National Intelligence, speaks in McLean, Va., Monday, July 18, 2022. (Saul Loeb/Pool via AP)


Bubble sort is a simple sorting algorithm. It works by repeatedly stepping through the list to be sorted, comparing each pair of adjacent items and swapping them if they are in the wrong order. The pass through the list is repeated until no swaps are needed, which indicates that the list is sorted. The algorithm gets its name from the way smaller elements "bubble" to the top of the list. Because it only uses comparisons to operate on elements, it is a comparison sort.
And it swaps when the first element is greater than second element.
If you see carefully u can see the array is sorted in ascending order (small to big).
Here is the java code for bubble sort.
2. When the number is already sorted, in bubble sort we keep doing the work.
Only after one pass the number will sorted so we don't need to compare any more.
So this is all about bubble sort :).


The Senate this month sharply criticized the Pentagon's business practices and information systems, calling them "ineffective," and urged the Defense Department to reform how it develops systems and improve its financial and information management.
In its report on the fiscal 2000 Defense authorization bill, the Senate Armed Services Committee said that while the Pentagon has made "great progress" over the past few years on acquisition reforms, particularly in buying more commercial products, DOD needs to extend reforms to its efforts in developing major weapons systems.
The report added that although DOD has a "significant investment in thousands of automated systems that support every facet of its operations, many of the potential benefits of information technology have not been fully realized." DOD spends roughly $11 billion on what it calls "pure" information technology systems and two to three times that on embedded and tactical systems.
The report laid many of the Pentagon's IT and business practice problems on what it called "a history of costly and long-standing software development problems."
Studies show that 35 percent to 50 percent of the development and maintenance work that DOD conducts on software goes toward reworking and correcting software defects, according to the committee's report.
Calling rework the "single biggest cost driver" in the DOD IT budget, the Senate directed the Pentagon to adopt best practices for its software development efforts, including risk management, metrics, better control of software changes during development, maximum use of commercial software and a minimization of duplicative software development programs.
The Pentagon did not respond to FCW requests for comment about its software development practices.
"Congress is starting to recognize the need for change, but its response uses the typical solution of throwing money at the problem," said retired Lt. Gen. Thomas McInerney, head of Business Executives for National Security, a non-profit advocacy group. "More money is not enough. Congress must also support efforts to change how the Pentagon does business. We may find a silver lining in the Kosovo quagmire if Congress and other opponents of change are shaken by the reality of the challenges facing today's military. Business as usual is no longer an option."
Despite the Senate's sharp criticism of DOD IT systems, the bill pumped additional funding into key battlefield and base networking IT systems in all four services. The committee allocated an additional $30.7 million for the Navy's Information Technology for the 21st Century, which will enable the Navy to harness the power of commercial networks and computers aboard ships and ashore. The increase boosts the total IT-21 budget to $515.6 million for fiscal 2000.
network-centric warfare to revolutionize warfighting. But we must also be efficient business managers. We must use the power of information to reduce the costs of doing business, or we'll never meet the continued fiscal challenges we face."
deployable satellite communications systems and $26.2 million for the Global Combat Support System-Air Force.
Army battlefield communications systems also received a boost, with the bill earmarking $50 million more for the tactical Warfighter Information Network, which would give the program $159.1 million in total funding. The committee wants to accelerate the installation of equipment designed to upgrade aging Army gear with advanced technology, including Asynchronous Transfer Mode switches.
James O'Neill, president of Lucent Technologies Inc.'s government solutions division, said, "Our experiences...have shown us that a high-tech communications infrastructure places critical and timely information in the hands of those who need it the most.


Danger and violence have always been part of Sue Dalston's East End upbringing. Unloved by her mother, abused by her father, and brutalized throughout her entire marriage, she's convicted of smashing her husband's skull in a final act of desperation. All that keeps her sane is knowing that she's done it to protect her four children. At last, they are safe from harm. When she is called up with murderess Matilda Enderby, their fates become inextricably linked. And no one - least of all Sue - could have predicted the consequences . . .
Martina Cole is a British crime writer, businesswoman, and occasional television presenter. Four of her novels, Dangerous Lady, The Jump, The Take and The Runaway have been adapted into high-rating television dramas. She has achieved sales of over fourteen million in the UK alone and her tenth novel, The Know, spent seven weeks on The Sunday Times's hardback best-sellers list.
An explosive story of East End violence, the terrors of prison life and the pursuit of justice against all odds, with a heroine whose heartbreaking story will stay with you forever.


Today we turn to Timothy Sellers, another participant in the NIMBioS Songwriter-in-Residence program. Our questions for him were the same as those for Kay Stanton, but his answers were totally different!
TS: At the risk of being boring but honest, I'm trying to reach people's hearts and minds through their ears. At the risk of being evasive and silly, I'm trying to glue the moon to the sun while cheating death and getting my glue for free.
TS: Extremely. To anyone interested in understanding the world, math and science are essential tools.
TS: I like to push songwriting into new, unexpected territory. Sometimes I want to share my curiosity and amazement about our universe. And I am frequently motivated by my concern about the fate of our planet and its biosphere.
TS: To me, my songs that involve science and math are exactly the same as love songs. Maybe it's a way for me to express the same spectrum of emotions without the obligation of singing explicitly about, say, being a teenager. Both songwriting paths are fine with me. For example, the early Beatles usually followed the teenager path; the later Beatles often chose more oblique angles.
As for opportunities, my frequent choice of geeky lyrical territory has turned off some potential fans but attracted a lot of others. I put the songs first and try not to worry about the rest.
TS: I'll remember the people I met, the beautiful stormy spring weather, and a hilariously terrible wine tasting. And I'll remember sitting in James Agee Park at various times of day and night, working on songs or reading.
TS: I love the sheer genius of Tom Lehrer. And I love artists who work science into the edges of their songs, like the Pixies or the Talking Heads.
TS: Thanks for taking an interest, Greg and friends! Keep in touch with me and Artichoke at www.artichoketheband.com.


text:
Mental health and addiction services overwhelmed with demand amid COVID-19 lockdowns
Ireland Hendry-Tennent
Related video: Advocates Jess Dyson and Kellie Lavender discuss eating disorders. Credits: Image - Getty; Video - The AM Show
This article deals with addiction, eating disorders and suicide.
Mental health and addiction services are struggling to keep up as a record number of Kiwis seek help amid the COVID-19 pandemic.
Addiction services specifically were overrun during the first lockdown in March as peoples' alcohol and drugs consumption increased.
Physical barriers to care such as non-essential surgeries being cancelled also took a toll on Kiwis, with support services fielding calls from people suffering mental health problems as a result.
Women with conditions such as endometriosis were among many who faced cancellations, forcing them to live in extreme pain until their surgeries could be rescheduled post-lockdown.
Endometriosis causes tissue similar to the lining of the uterus to grow outside the womb and can cause painful symptoms such as debilitating period pain, lower back pain, IBS symptoms, abnormal menstrual bleeding and pain with sex.
Opinion: I recovered from anorexia, and I learned it's a misunderstood mental illness
'It's a disgrace': The Kiwi women being ignored by NZ's health system
As a result Endometriosis New Zealand (ENZ) saw a huge influx in women who were suffering severe mental health issues.
And ENZ isn't alone, eating disorder support services have also seen a huge surge in demand.
Eating Disorders Association of NZ chairperson Nicki Wilson told Newshub they have seen an "incredible increase".
"We are receiving contacts from people needing help, or advice and information at four times the level that we experienced previously at the same time last year."
And Wilson says "overburden services" aren't keeping up, leaving sufferers with long waitlists.
"Waiting lists and waiting times at the moment in the services are just dreadful, absolutely dreadful.
Wilson says no one should be put on a waitlist for a life-threatening illness like an eating disorder. Anorexia has the highest mortality rate of any mental disorder.
Other eating disorder services including charities, private providers and some DHB teams are all seeing increased demand as well.
"It is really stretching them… I cannot stress how hard they are working and how dedicated they are but the system is not coping," Wilson said.
"I would go so far as to say it's a scandal. It's just dreadful."
Do you know more about this issue? Contact Ireland Hendry-Tennent in confidence by email: irelandhendrytennent@mediaworks.co.nz
Wilson is begging for extra support and more education about eating disorders for GPs and medical staff.
"We really are asking for attention to be paid to this sector. We have seen a huge increase and just terrible suffering and an inability to access services and it's just not acceptable."
'The perfect storm'
Eating disorder advocate Jess Dyson says the lockdown has been "the perfect storm" for developing an eating disorder.
"It's intensified the struggle… for a lot of people and made things a lot worse."
Dyson said her coaching service has been inundated with people in need.
"I've seen a lot of people seeking out help. Even existing clients who I would normally see once a week need to see me three times a week at the moment."
The lockdown has been "the perfect storm" for developing an eating disorder. Photo credit: Getty Images
A spokesperson for the Ministry of Health said mental health and addiction providers were considered essential services during the lockdown but the way these services were provided may have changed.
"Due to these restrictions and the need to prepare for a possible surge in COVID-19 positive cases at that time there may have been restrictions, or a higher threshold to gain access to some essential services, including mental health and addiction services."
The spokesperson said the Ministry is not aware of particular concerns or issues with accessing eating disorder services post-lockdown.
They said the Ministry is in conversation with EDANZ to monitor and respond to needs as appropriate.
Not a lone issue
Endometriosis New Zealand chief executive Deborah Bush said 568 women contacted them in a state of despair during the lockdown. She said some of the women were suicidal and had no hope.
"Some were completely broken due to their long-awaited surgeries being cancelled with no rescheduling date in sight," she said.
During the level 4 lockdown endometriosis surgeries were often cancelled or postponed which Bush acknowledged was "understandable and unavoidable".
However, she said it has been made worse by a lack of Government and Ministry of Health action in the past, citing a "failure to support the implementation of long-awaited clinical guidelines for the treatment of endometriosis".
People with endometriosis often face long wait times and struggle to get diagnosed. But even with a diagnosis, they can spend years waiting for life-altering surgery.
Endometriosis NZ co-founder and CEO Deborah Bush. Photo credit: ENZ
One woman says she has had endometriosis symptoms since 2005 but wasn't diagnosed until 2019 because her hospital referrals kept being rejected by Manukau DHB. She says despite having extreme pain the DHB was too under-resourced to see her.
When she was finally diagnosed in September 2019, her endometriosis was so severe that it was recommended she be seen by a specialist within 6 weeks.
However, despite following up in December and February she didn't meet with a specialist until March 2020. The specialist recommended advanced surgery.
But by September she still hadn't had the surgery and her pain was so bad she couldn't walk.
The specialist couldn't give a timeline for when she might get surgery leaving her so desperate that she considered refinancing her mortgage or selling assets so she could afford private care. Thankfully in late September, she was finally able to get surgery.
The Ministry of Health said it published the clinical guidelines in March and shared them with "relevant medical staff"
"The Ministry strongly encourages all relevant healthcare professionals to familiarise themselves with the guidance so they can incorporate them into their care," a spokesperson said.
"The guidance is intended to inform local clinical pathways and referral guidelines to improve the quality and consistency of clinical practice in the diagnosis and management of endometriosis."
The spokesperson said there was a "considerable decrease" in the number of services delivered during the lockdown from March to May but DHBs are now working hard to reduce growing waiting lists and backlogs.
They acknowledged that many women suffer silently with endometriosis for years before being diagnosed.
However, Bush said the Ministry hasn't followed through leaving 130,000 women and girls "living with this debilitating disease".
Where to find help and support:
Shine (domestic violence) - 0508 744 633
Women's Refuge - 0800 733 843 (0800 REFUGE)
Need to Talk? - Call or text 1737
What's Up - 0800 WHATS UP (0800 942 8787)
Lifeline - 0800 543 354 or (09) 5222 999 within Auckland
Youthline - 0800 376 633, text 234, email talk@youthline.co.nz or online chat
Samaritans - 0800 726 666
Depression Helpline - 0800 111 757
Suicide Crisis Helpline - 0508 828 865 (0508 TAUTOKO)
Shakti Community Council - 0800 742 584


BUENOS AIRES, Argentina -- No. 6 seed Nicolas Jarry of Chile was eliminated in the first round of the Argentina Open on Monday.
Italian Lorenzo Sonego knocked out Jarry with a 6-7 (3), 6-4, 6-3 victory at Buenos Aires Lawn Tennis Club.
Albert Ramos-Vinolas of Spain, Christian Garin of Chile and German Maximilian Marterer also advanced.
Ramos-Vinolas beat Brazilian Rogerio Dutra Silva 6-3, 6-4, and Garin eliminated Felix Auger-Aliassime of Canada with a 3-6, 7-5, 6-3 win at the clay-court tournament. Marterer posted a 6-4, 6-2 victory over local favorite Facundo Bagnis.


text:
Skäggfibblor (Tolpis) är ett släkte av korgblommiga växter. Skäggfibblor ingår i familjen korgblommiga växter.

Kladogram enligt Catalogue of Life:

Källor

Externa länkar

Korgblommiga växter

redpajama_set_name: RedPajamaWikipedia


text:
World leaders to address high-level, special session of UN General Assembly on Covid-19
PTI United Nations | Updated on December 02, 2020 Published on December 02, 2020
The two-day session will allow stakeholders to share their experiences in fighting the pandemic, reflect on the global response to date, and forge a united path forward
World leaders, the top leadership of the UN and vaccine developers will address a two-day special session of the UN General Assembly on Covid-19 this week and discuss the pandemic's impact as well as the multi-faceted, coordinated response required to address the greatest global health crisis in decades.
The Special Session of the United Nations General Assembly in Response to the Coronavirus Disease (Covid-19) Pandemic will take place on December 3 and 4 at the UN Headquarters.
The world organisation said government leaders, United Nations' principals and other relevant stakeholders would be able to engage in dialogue on the impact of the pandemic on people, societies and economies and discuss the multi-faceted, coordinated response required to address this crisis.
Serum Institute of India Chief Executive Officer Adar Poonawalla will also address the session through a pre-recorded video on December 4. BioNTech co-founders Ugur Sahin and Ozlem Tureci, vaccine team leader at Oxford University Sarah Gilbert and Chief Executive Officer of GAVI (the vaccine alliance) Seth Berkley will address the special session virtually.
AstraZeneca and the University of Oxford are working on a Covid-19 vaccine, while global drugmaker Pfizer and BioNTech announced their vaccine candidate is 95 per cent effective.
Itinerary and Speakers' list
World leaders expected to address the session are Afghan President Ashraf Ghani, French President Emmanuel Macron, Nepalese Prime Minister KP Sharma Oli, New Zealand Prime Minister Jacinda Ardern, German Chancellor Angela Merkel.
President Donald Trump is not listed as a speaker for the session and US Secretary of Health and Human Services Alex Azar will address the high-level meeting.
The two-day special session will allow many stakeholders to share their experiences in fighting the pandemic, reflect on the global response to date, and forge a united, coordinated, and people-centred path forward.
The Covid-19 pandemic, which has claimed more than 1.3 million lives and infected more than 54 million people globally, "is not only the greatest global health crisis since the creation of the United Nations 75 years ago, it is also a humanitarian, socio-economic, security and human rights crisis," the world body said.
The session's first day will feature statements by the President of the General Assembly Volkan Bozkir, Secretary-General Antonio Guterres, President of the Security Council for the month of December South African Ambassador Jerry Matthews Matjila and Chair of the Movement of Non-Aligned Countries Ilham Heydar oglu Aliyev. The General Assembly will then hear from world leaders.
According to the speakers list, there are 141 speakers inscribed, including 53 heads of state, 39 heads of government, four deputy prime ministers and 38 ministers.
The second day will feature speeches from WHO Director-General Tedros Adhanom Ghebreyesus and other UN and inter-governmental agencies.
Bozkir's Spokesperson Brenden Varma, replying to a question on whether it was far too late to hold the special session on Covid-19, said the President of the General Assembly agrees that it is already too late to have this meeting, which should have been held in the summer as the coronavirus cases were rapidly increasing across the world.
Varma said member states have come together and decided to hold this special session on Covid-19. And the point of this is to recommit to multilateralism, he said.
Currently there are a lot of responses to Covid-19, but the point of the session is to bring countries together, along with UN actors, the private sector and vaccine developers to work together to see where we are, to take stock and to identify gaps and challenges and then to move forward together so we have a unified response that actually makes sense and that can actually combat this pandemic, he said.
United Nations (climate change)


text:
Q: Copy the 'explicit' or 'E' symbol from songs in the iOS Music app I have songs in my Music app that are marked as 'explicit'.
Is there a way to copy this 'explicit'/'E' symbol so I can use it somewhere else?

A: He is probably looking for the following unicode character : Negative Squared Latin Capital Letter E
The letter :

NB: The letter is not visible on my Windows. My iPhone displays it.

A: The 'E' is not text, it is artwork.
iTunes on your Mac has the same artwork. This artwork is located within the iTunes app. This is how you can find it:

*

*Go to /Applications

*Right click 'iTunes' and select 'Show Package Contents'

*Now go to 'Contents' -> 'Resources' -> 'English' (or any other installed language)

*In here you will find the artwork in png format. The 'ViewLineItemRatingE' is the one you are looking for. The @2x suffix means that it is double the resolution and is meant for retina displays.

Note: I do not know about copy rights on this artwork. This might differ between countries as well.

redpajama_set_name: RedPajamaStackExchange


While regular Greubel Forsey timepieces are already esoteric in their own right, the Art Pieces lineup takes the aesthetical designs yet a step further.
The flagship of the brand's SIHH 2019 line-up, the Art Piece Edition Historique is avant-garde in style, emphasising two signature elements of the brand – the double, inclined 30° tourbillon and relief micro-engraving of the Greubel Forsey philosophy.
The double axis inclined tourbillon is not new but nevertheless still impressive; it features the same tourbillon carriages found in other Greubel Forsey double tourbillon movements.
It rotates the balance wheel in multiple planes which, in theory, averages out positional errors more uniformly as compared to a regular movement. While the outer carriage rotates gradually at one revolution every four minutes, the inner carriage completes rotating in 60 seconds.
The tourbillon is prominent atop the frosted, blue coated titanium main plate, which is deeply recessed in contrast to the raised half of the dial, giving a strong sense of depth. This is further emphasized by the massive domed sapphire crystal and large case size of 44mm by 15.95mm, which gives an excellent all-round view of the geometric dial surfaces.
The raised half of the dial is of strong interest – being intricately engraved in relief with the brand's values, done so small as to resemble hieroglyphics. The engraving extends to the wide flanks of the raised dial, further utilising the architectural depth as a visual advantage.
Interestingly, the only apparent time indication on the dial is a red marker for the hours and a small sub-dial for seconds. The minutes are in fact, displayed in a window covered with a shutter that's opened on-demand via a pusher on the crown. The lower half of the dial is simpler, with a blued steel pointer to indicate the 72-hour power reserve.
In stark contrast to the dial, the caseback is minimalistic – being dominated by a large, frosted three-quarter plate. Breaking the monotony of the expansive plate are gold chatons holding the jewelled bearings, and also relief-engraving of the signatures of Robert Greubel and Stephen Forsey.
Nevertheless, the unadorned appearance belie what's underneath as the movement consists of a staggering 475 parts, with 130 for the tourbillon alone. This is plenty for what is essentially a time-only wristwatch with a power-reserve indicator and a jumping complication for the minutes aperture shutter.
The movement is also equipped with two mainspring barrels coupled in series, with one having a slipping clutch as found in automatic movements to prevent overwinding.
Either way, the view still remains interesting with the underside of the intricate tourbillon carriages visibly held by a slender, black-polished steel bridge that mirrors the bridge on the front. Not to mention the elaborate and meticulous finishing abundantly present throughout the entire movement that Greubel Forsey is revered for.
The Greubel Forsey Art Piece Edition Historique is limited to 33 pieces, with the first 11 pieces in platinum and subsequent models in other materials. Priced at CHF555,000 before taxes.


text:
Science Education > Inside Life Science > Untangling the Source of Ouch and Itch
Untangling the Source of Ouch and Itch
By Joseph Piergrossi
Many of us have experienced the sting of a bad sunburn and the itchy, peeling skin that follows. For decades, scientists suspected that pain and itch were the same thing, only expressed at different intensities: Itch was just light pain, and pain was strong itch.
Scientists have been trying to better understand how these sensations occur on a cellular level. Recent studies funded by the National Institutes of Health show that pain and itch stem from a complicated process involving many types of neurotransmitters, chemicals that transfer nerve signals to the brain, and receptors, cell surface proteins that accept those signals. A major goal of this line of research is to find better ways to tackle chronic pain and itch conditions, which often persist despite use of soothing medicines.
Defining Pain and Itch
This cross-section shows the layers of skin, from the epidermis on the surface to the underlying fat. Keratinocytes, cells that start the transmission of sensory signals, live at the lower level of the epidermis near the dermis. Credit: NIGMS.
Pain and itch are both forms of nociception, the sensing of danger through stimulus from the environment. At a basic level, pain tells the body that there either has been an injury or that one is imminent. Nociception is the reason why we feel a burning sensation when we get too close to a flame. Itch, clinically known as pruritus, signals that there is an irritant or potential toxin around.
In both cases, the skin is vital to signaling. Cells called keratinocytes live at the base of the epidermis, the surface layer of the skin, and send sensory signals to nearby nerve endings. If skin were a stone wall surrounding a town, then keratinocytes would be the watchtowers that alert the townspeople about approaching intruders. The nerve endings transmit the signal through circuits of multiple nerve cells toward the brain.
But pain is not limited to the skin. The same pain receptors exist on nerve endings inside the body, producing the sensation of an achy muscle or stomach cramp. That's not the case with itch receptors. They only go as far inside the body as the mucous membranes, such as inside our nostrils or throat. This is why our internal organs never seem itchy. If they did, imagine how hard they'd be to scratch!
Pain and itch can come about in different ways. Itch, for example, can be brought on by chemicals called histamines. Histamines are a critical part of the allergic reaction that we feel with a mosquito bite or with hives. Histamine-mediated itch can be relieved with an antihistamine. But the majority of chronic itch doesn't involve histamine, making it difficult to medicate. In fact, that sort of histamine-independent itch is a common side effect of pain medications such as morphine.
Scientists took this connection between pain and itch as another clue that the two are related, but they still weren't sure whether itch was simply dulled pain or a distinct sensation. They started looking for answers in the nerve cells.
Finding Pain and Itch
Xinzhong Dong and his team at Johns Hopkins University found neurons containing both TRP and Mrgpr receptors transmitted itch instead of pain. This meant a response to capsaicin (ball-and-stick molecular model) evoked itch instead of pain in those neurons. In the background (blue) is a micrograph of itch nerve fibers in mouse skin. Credit: Tim Phelps, JHU.
One answer comes from scientists at Johns Hopkins University. The researchers found two families of receptors on nerve cells that receive signals from keratinocytes: TRP receptors mediate pain and itch, and Mrgpr receptors mediate histamine-independent itch.
Scientists made these findings by turning off different types of receptors in mice, which have a similar nervous system to humans. By exposing the mice to chloroquine, an antimalarial drug that can cause itching as a side effect, and capsaicin, the "hot" compound in spicy peppers, they could tell what the mice sensed.
"If the mouse felt an itch, it would scratch behind its ears with its hind leg," says Xinzhong Dong, who led the study. "When it felt pain, it would rub its cheek with its front leg."
Mice lacking an Mrgpr "itch" receptor specific to chloroquine could feel pain but not itch. Mice that didn't have a TRP "pain" receptor that responds to capsaicin actually found capsaicin itchy instead of painful.
Dong explains that these findings indicate that neurons containing only the TRP receptor process pain sensation. On the other hand, neurons containing both the TRP receptor and the Mrgpr receptor transmit itch signals.
The results also suggest that pain circuits can inhibit itch circuits, so only one signal is sent at a time—explaining why pain and itch rarely happen simultaneously.
Today, researchers are pursuing drug compounds that directly block pain and itch receptors to deliver more targeted relief with fewer side effects.
The research reported in this article was funded in part by the National Institutes of Health under grants R01GM087369, R01NS054791, P01NS047399, R01NS014624 and R01NS070814.
Fact Sheets on Anesthesia, Burns and Trauma
Video: The Body's Response to Traumatic Injury (video no longer available)
Life After Traumatic Injury: How the Body Responds
This Inside Life Science article also appears on LiveScience.


The directory path is created with the access permissions specified by mode and restricted by the umask(2) of the calling process.
The directory's owner ID is set to the process's effective user ID. The directory's group ID is set to that of the parent directory in which it is created.
The mkdirat() function is equivalent to mkdir() except that where path specifies a relative path, the newly created directory is created relative to the directory associated with file descriptor fd instead of the current working directory.
If mkdirat() is passed the special value AT_FDCWD (defined in <fcntl.h>) in the fd parameter, the current working directory is used and the behavior is identical to a call to mkdir().
Search permission is denied for a component of the path prefix, or write permission is denied on the parent directory of the directory to be created.
The new directory cannot be created because there is no space left on the file system that will contain the directory.
There are no free inodes on the file system on which the directory is being created.
The new directory cannot be created because the user's quota of disk blocks on the file system that will contain the directory has been exhausted.
The user's quota of inodes on the file system on which the directory is being created has been exhausted.
The mkdir() and mkdirat() functions conform to IEEE Std 1003.1-2008 ("POSIX.1").
A mkdir() system call first appeared in Version 1 AT&T UNIX. It was renamed to makdir() in Version 2 AT&T UNIX. However, it did not exist from Version 4 AT&T UNIX to 4.1BSD; in those releases, mknod(2) had to be used. Since mkdir() reappeared in 4.1cBSD, it no longer requires superuser privileges and it automatically creates the '.' and '..' directory entries.
The mkdirat() system call has been available since OpenBSD 5.0.


Its geology is based on igneous and metamorphic rocks which shows the influence of the Palestina's fault due to the presence of stretch marks in the fault and minerals lineation. The big movement of material in the zone are associated to a fracture a cizalla zone where its possible to see folds zone.
In the area of the Palestinian fault are mainly metamorphic and igneous rocks. These rocks mainly belong to the "Cajamarca Series" complex, which comprises a varied amount of shale and also contains lower amounts of quartzite that were intruded by dykes; in general terms the degree of metamorphism is considered low to medium in green schists. These metamorphic rocks are essentially affected by regional metamorphism and some by dynamic metamorphism. In addition to that, due to the deformation of the fault, many allochthonous materials are presented. These materials are composed mainly of rocks such as marble, feldspathic gneiss, diorite, gabros, cretaceous slates among others. The extreme south presents fisural volcanism, from Ruiz to Quindío.
The Palestina's fault is associated to minor faults which crosses it obliquely, for instance San Juan's fault and El Placer. As it is a stike fault, its biggest efforts comes from horizontal compressive forces.
the fault affects substantially metamorphic and igneous rocks, Precambrian rocks and the Cretaceous, also follows an approximate N 5 ° E course and affects Proterozoic metamorphic rocks and Mesozoic intrusive rocks. It proceeds in a north - south direction, aligning the River The volcano in a southerly direction until it meets the San Bartolomé River, which dissects almost perpendicular to the block on the eastern side corresponding to the Metamorphic Complex of San Lucas, represented by gneisses, quartz - feldspathic.


Qliktag is looking for Mobile Application Developers to work at our offshore development center in Pune. Qliktag is an innovative software startup working in cutting edge software solutions in the field of consumer transparency applications, mobile engagement and has an excited roadmap charted out. The development team that we've been building out in Pune, India is highly driven, passionate about what we're working on and are committed to developing stellar software products used on a global level. We're looking for contributors!
Very strong foundation in mobile development basics & ability to learn and adapt quickly to new technologies like Ionic Framework, Angular, Flutter etc.
Previous experience in Startups and quick joiners are preferred.


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Getting sick of Nick Kyrgios and Bernard Tomic? Here's a rising young Aussie star with a mountain of class you can get behind.
Asian Cup: Awer Mabil talks to Fox Sports moments after the Socceroos beat Syria. Mabil talks about the inspirtation behind the celebration he acted out after he scored the first goal of the game.
Fresh Aussie winger Awer Mabil pulled off what Mark Bosnich described as "one of the goals of the tournament" in the first half against Syria last night, curling a brilliant left-footer around two defenders to put Australia on the board.
A litany of penalty bungles sent the match into chaos as the Socceroos narrowly advanced their campaign into the round of 16 with a late 3-2 win over their opponents.
But for Mabil, things more important than mere football were on his mind as he wowed for the green and gold.
The 23-year-old, who grew up in a Kenyan refugee camp, had a message for the world after slotting his stunning goal. In one of the more peculiar goal celebrations seen in recent times, Mabil placed two fingers to his mouth and then covered that hand with his other.
He later revealed his gesture was a message to people suffering from mental illness.
"I want them to know that people do care for them and it's all in the mind, they need to find someone to talk to," Mabil said.
"If I can create anything for them to be aware of and for people to see, that people do suffer from this, I'm the first toput my hand up and that's why I created that.
The gesture came just hours after Sudanese-born AFL star Majak Daw posted an update following his heartbreaking bridge fall late last year.
Mabil, who earned his first run with the Socceroos late last year, has also received an award year for his philanthropic work.
He and his brother founded a charity called Barefoot to Boots which provides football boots to kids and also offers educationand healthcare outcomes for children in the camp where he was born after his parents fled from Sudan in 1994.
Mabil says his goal celebration message was a collaboration between himself and former FC Midtjylland teammate Pione Sistoin Denmark.
"He's from Sudan also. We talk a lot and I was just sitting there and I was like, 'I want to create something for people tobe aware of, to bring peace to the mind,'" Mabil said.
"I just came up with that. From then on, ever since I scored I just did it." By his own admission Mabil struggled with lonelinessas he attempted to make his way as a professional footballer after moving to Denmark as a 19-year-old. That experience and those of others around him has taught him the importance of speaking up and sharing problems rather than leaving them in the dark. "It's easy to be isolated, but there's people out there who care for you," he said.
"I have such a family-orientated club in Denmark, who helped me a lot, and I've seen a lot of people suffering from it.
His explosive performance for Australia certainly turned a few heads in the footballing world as the Socceroos look to the future.
It was a call that baffled many, both at the ground in the UAE and in living rooms in Australia.
When Mexican referee Cesar Ramos awarded Syria a penalty in the 80th minute of a crucial Asian Cup clash against Australia, it was hard to see why. Star striker Omar Al Soma crumpled to the turf on Tuesday as Syria launched a harmless free kick into the arms of Socceroos' goalkeeper Mat Ryan. After a moment's thought, Ramos blew his whistle — a decision met with a mixture of disgust and bemusementby Australia's players.
Replays showed it was one of Al Soma's own teammates who had tripped the striker as he ran into Australia's penalty area.
The Syrian stepped up and slotted the controversial penalty to level the match at 2-2 and send the Syrian players and fansinto frenzy.
"He didn't give me much of an explanation when I asked," Socceroos captain Mark Milligan said of the bizarre call.
"But I don't have a whistle in my hand.
"It's football, these things happen. Sometimes they go for you, sometimes they go against you. We can't control that." Despite a late onslaught, Australia secured their passage to the competition's second round and eliminated Syria from the tournamentwhen Tom Rogic stroked home a 93rd-minute winner.


text:
Matthew Pfeffer
Mr. Pfeffer joined our Board of Directors in May 2015 and serves as the Chair of the Audit Committee. Mr. Pfeffer has served as the Corporate Vice President and Chief Financial Officer of MannKind Corporation since April 2008. Since January 2016, Mr. Pfeffer has been Chief Executive Officer of MannKind Corporation as well as remaining the Chief Financial Officer. Previously, Mr. Pfeffer served as Chief Financial Officer and Senior Vice President of Finance and Administration of VaxGen, Inc. from March 2006 until April 2008, with responsibility for finance, tax, treasury, human resources, IT, purchasing and facilities functions. Prior to VaxGen, Mr. Pfeffer served as CFO of Cell Genesys, Inc. During his nine year tenure at Cell Genesys, Mr. Pfeffer served as Director of Finance before being named CFO in 1998. Prior to that, Mr. Pfeffer served in a variety of financial management positions at other companies, including roles as Corporate Controller, Manager of Internal Audit and Manager of Financial Reporting. Mr. Pfeffer began his career at Price Waterhouse. Mr. Pfeffer graduated from the University of California, Berkeley and is a Certified Public Accountant.


text:
Apple pressing event in Chester is a hit
RESIDENTS had a pressing invitation to make their own apple juice – and responded with a thumbs-up.
Carmella de Lucia
The first of four public apple pressings in Chester took place last weekend outside Deli Vert in Faulkner Street, Hoole, and proved a big hit with the locals.
The events, organised by environmental group Transition Chester, encourage people to put their spare apples to good use and make them into fresh juice, using an apple press.
More than 200 litres of apple and pear juice was pressed from fruit brought by residents last Saturday, with pressing continuing solidly from 10am-2pm.
Simon Brown of Transition Chester said: "We had a queue waiting for us as we set up the stand and were so pleased that so many people really wanted to make use of their surplus apples and didn't want them to go to waste.
"We hope the other events we have planned will be equally as successful."
More apple pressing events will take place during October:
Saturday, October 8, from 10am-2pm at Westminster Park Shops, Five Ashes Road, Chester.
Saturday, October 15, from 10am-2pm at Blacon Parade, Blacon.
Saturday, October 29, from 10am-2pm outside the Kingsway Community Cafe at Kingsway Shops, Newton.
Blacon
Hoole
Cheshire shipyard to be turned into leisure marina and housing estate
Cheshire West and Chester CouncilPlans for new homes at the site were approved in 2020, but have faced delays ever since


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Home::Blockchain::The Future of Blockchain Series Episode 2
Episode 2: Usage in Commercial Lines
Photo Courtesy of
Blockchain has incredible potential to streamline business functions and open up opportunities for a wide range of innovations
Blockchain provides a single source of truth that is kept up to date in real time and is accessible (through permissions) by all stakeholders. Having that source creates unprecedented efficiencies by eliminating much of the phone tag and other wastes of time that come with the document-sharing that characterizes so many processes in the insurance industry. This webinar dives into the technology's use in commercial lines, highlighting production-ready use cases in surety bonds, workers' comp and certificates of insurance. The possibilities are breath-taking.
Watch to learn:
Where blockchain is about to make a big impact
The road map for the future of blockchain
The status of active use cases and their testing schedule
How you can prepare to reap the benefits
Don't miss this free on demand panel discussion.
Sean Ringsted
Chief Digital Officer
Sean Ringsted is Chief Digital Officer at Chubb, the world's largest publicly traded property and casualty insurance company and the largest commercial insurer in the U.S.
Mr. Ringsted leads Chubb's digital efforts aimed at transforming the company into a digitally integrated organization.The initiatives involve all areas that produce and support Chubb's business into a digital environment, including underwriting, sales and service functions that touch policyholders, prospective customers, distribution and internal operations and technology.
Mr. Ringsted has more than 25 years of experience in the insurance industry and is often quoted in news publications as an industry expert. In addition to his role as Chief Digital Officer, Mr. Ringsted has served as the company's Chief Risk Officer since 2008, prior to ACE's acquisition of Chubb in 2016. Mr. Ringsted was named Executive Vice President, ACE Group, in March 2014.
Mr. Ringsted holds a Bachelor of Science degree in Biochemistry from Bristol University and a Doctorate in Biochemistry from Oxford University. He is a Fellow of the Institute of Actuaries (FIA).
Patrick Schmid, PhD
The Institutes RiskStream Collaborative
Patrick G. Schmid is vice president of The Institutes RiskStream Collaborative. In this role, he oversees products, operations and technology; coordinates efforts among RiskStream Collaborative insurers, brokers and reinsurers; and provides thought leadership for The Institutes.
An economist with a passion for blockchain, Dr. Schmid has worked in risk management and insurance for over a decade, researching trends on important market issues. Working as an economist for Moody's Analytics before joining The Institutes, he has also taught economics and related subjects at a number of Philadelphia-area colleges and universities.
Schmid formerly served as the director of research for the Insurance Research Council (IRC), a division of The Institutes. As the IRC's research director, he was responsible for providing timely and reliable information based on extensive data collection and analyses. His research examined public policy matters that affect insurers, consumers and the general public.
Dr. Schmid has published research in a variety of property-casualty insurance areas. He frequently presents research findings to industry executives, industry associations and company management. He has testified before regulatory and legislative bodies. Dr. Schmid is often quoted in insurance periodicals, and his research has been reprinted in various industry-related academic journals.
Prior to working in the Insurance industry, Dr. Schmid was an economist for Moody's Analytics.
Dr. Schmid has a PhD in economics from Temple University. He has taught economics or related subjects at a number of Philadelphia-area institutions, including the Wharton School, Albright College, Temple University and St. Joseph's University.
Paul Carroll
Insurance Thought Leadership
Paul is the co-author of "The New Killer Apps: How Large Companies Can Out-Innovate Start-Ups" and "Billion Dollar Lessons: What You Can Learn From the Most Inexcusable Business Failures of the Last 25 Years" and the author of "Big Blues: The Unmaking of IBM", a major best-seller published in 1993. Paul spent 17 years at the Wall Street Journal as an editor and reporter. The paper nominated him twice for Pulitzer Prizes. In 1996, he founded Context, a thought-leadership magazine on the strategic importance of information technology that was a finalist for the National Magazine Award for General Excellence. He is a co-founder of the Devil's Advocate Group consulting firm.
Did you miss the first in our blockchain series? View it here.
More articles by Insurance Thought Leadership:
Six Things Newsletter | January 5, 2021
6 Questions for Stephen Applebaum
Email Insurance
The Insurer's Customer Acquisition Playbook


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Perion Completes Acquisition of Conduit's ClientConnect
Tel Aviv app developer calls deal 'great stepping stone,' signals new acquisition in future.
$800 million company formed by Perion-Conduit merger
Game over in Download Valley?
Conduit in talks to acquire Perion for some $200 million
Babylon puts out feelers to acquire startup myThings
Tech roundup / Israeli firms paid ransom to CryptoLocker -- in vain
Israel's Perion Network said it was targeting annual revenue of $1 billion in the next five years following the acquisition of Conduit's ClientConnect business.
The Tel Aviv-based Perion completed the purchase on Thursday in an all-stock deal worth $660 million, giving the company a platform designed to provide give mobile application publishers and developers a way of improving their distribution and money-making capabilities.
"My plan three years ago was to build a billion dollar company in Israel," Perion CEO Joseph Mandelbaum said in an interview with Reuters. "My internal goal is it will take three to five years to get there."
Mandelbaum said about a quarter of mobile apps never get downloaded, except perhaps by the developer's friends and family, while 98% of apps earn less than $5,000 a year. Citing studies, Perion also said 76% of consumers find free versions of apps sufficient.
"The toughest thing is getting traffic and making money," Mandelbaum said. Perion shares, which rose 35% in 2013 on top of a 126% advance in 2012, closed up 2.45% on Nasdaq Friday.
Mandelbaum said the acquisition of the much larger ClientConnect would allow Perion to help more mobile apps find paying customers. Perion, he noted, was able to make money from its main products, IncrediMail and Smilebox, through search partnerships with Yahoo!, Google and Microsoft's Bing.
On its own, Perion, founded in 2000 and whose key shareholders include Benchmark Capital and JP Morgan Chase, is expected to post 2013 revenue of between $102 and $104 million, up from $61 million in 2012. Including ClientConnect, 2013 revenue would be about $400 million.
Mandelbaum declined to give an outlook for 2014 but said the company expects to grow sales and profit, especially as the ClientConnect deal is immediately positive for earnings.
"This deal is a great stepping stone," Mandelbaum said. "We are not where we want to be yet. We have to do more investments and acquisitions to fill in the gaps."
He said Perion aims to improve its presence in the mobile sector, a tougher area for advertising than on desktop computers, and in analytics.
"We haven't even scratched the surface," he added. "We have terabytes of data to help ourselves and publishers make more money."
Perion founders Ofer and Yaron Adler. All in the family.Guy Ravitz


2008-12-18T14:04:59-05:00https://images.c-span.org/Files/7bc/282951-m.jpgStephen Hess, author of What Do We Do Now? A Workbook for the President-Elect, moderated a panel on the role of the White House press secretary, especially in the outset of a new administration. Current and former White House press secretaries spoke about their experiences, the routine and daily job of the press secretary, crisis management, maintaining good relations with the news media, and the changing nature of the media and the news cycle. Following their remarks they answered questions from the audience.


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HALDIMAND – The Ontario Provincial Police (OPP) Haldimand County Detachment is reminding the public to "think before you post" after a social media post intended as "a joke" caused alarm and concern for staff and students at Mackinnon Park Secondary School in Caledonia, Haldimand County, Ont. On Monday March 20, 2017, OPP responded to a weapons
HALDIMAND – The Ontario Provincial Police (OPP) Haldimand County Detachment is reminding the public to "think before you post" after a social media post intended as "a joke" caused alarm and concern for staff and students at Mackinnon Park Secondary School in Caledonia, Haldimand County, Ont.
On Monday March 20, 2017, OPP responded to a weapons complaint after school staff and parents reported a concerning image and comment posted on a social media site.
Witnesses reported the image displayed a female holding, what appeared to be a firearm, with the comment "don't come to school tomorrow".
Staff members at Mackinnon Park Secondary School were able to identify the female in the photo as one of their students.
OPP investigation determined that two female students were involved.
The female students were located and spoken to, and their parents were notified.
Both female students told police they only intended the image and comment post as a joke and realized it had gone too far.
The alleged firearm in the photo was located and determined to be an "air soft" pistol.
OPP were able to determine that there was no cause for public safety.
School staff is dealing with the matter.
"People need to really think of the consequences before they post comments and images on social media. These students may have intended the social media post to be a joke, but there is simply no joke about this," said Constable Rod LeClair, Haldimand County OPP.
Updates and reports by the Two Row Times Staff, send your inquiries to info@tworowtimes.com


We present an unbiased method to globally resolve RNA structures through pairwise contact measurements between interacting regions. RNA proximity ligation (RPL) uses proximity ligation of native RNA followed by deep sequencing to yield chimeric reads with ligation junctions in the vicinity of structurally proximate bases. We apply RPL in both baker's yeast (Saccharomyces cerevisiae) and human cells and generate contact probability maps for ribosomal and other abundant RNAs, including yeast snoRNAs, the RNA subunit of the signal recognition particle and the yeast U2 spliceosomal RNA homolog. RPL measurements correlate with established secondary structures for these RNA molecules, including stem-loop structures and long-range pseudoknots. We anticipate that RPL will complement the current repertoire of computational and experimental approaches in enabling the high-throughput determination of secondary and tertiary RNA structures.


We developed this recipe with fresh asparagus, because they are in season during the spring and early summer. But the recipe works well with tinned asparagus salad cuts.
Butter a 24 cm flan dish really well with soft butter and shake fresh breadcrumbs in the dish, so that some of the crumbs adhere to the bottom and sides. Place the dish in the freezer to set the crumbs, while making the filling.
Adjust the oven rack to the middle position. Preheat the oven to 170°C.
Steam the asparagus for 3 minutes. Toss them with the olive oil and leave to cool. Cut off 3cm of the tips. Reserve the tips to garnish with, after the quiche is baked. Slice the rest of the stems into 2 cm lengths.
Season the chopped onion with Green Onion Seasoning. Sauté the onion in the oil/butter mixture until completely soft and beginning to brown slightly. Remove from heat. Add the steamed asparagus stems (not the tips) and ham.
Beat the eggs with the cream. Toss the White Sauce Powder with the grated cheese and sprinkle half of this mixture evenly over the base of the prepared dish.
Top with asparagus, ham and onion mixture. Mix the remaining cheese mixture into the egg mixture. Pour the egg mixture over the asparagus.
* Vegetarians can happily leave out the ham and increase the cheese to 1 cup.


There was an older lady sitting at the table opposite mine at the Burger King in Central City. Immediately she started chatting away. She had diabetes and needed a sugar boost, she told me. I didn't have the heart to tell her my excuse to be there was to buy a Rugrats watch for myself.
The conversation went on to relatives suffering from diabetes as well, and from there on to all the family members she had lost in the last five years. Sisters, husband, son. It turned out her husband had died two years ago to the day and she needed to talk.
I joined her at her table, for I wanted to listen; she looked so vulnerable, dressed in a pink blouse, her smile shy, but at the same time inviting. At one point during the conversation when I touched her hand she was shocked to find mine so cold and for the next ten minutes she sat there rubbing them warm while talking.
She looked at me inquiringly. I of course had no scientific explanation, but the funny thing was I believed her. She offered her own conclusion: "I think sometimes God crosses my wires. " I could only agree with her, God sometimes has a tendency to do just that.
During our hour long conversation she displayed intelligence and broad general knowledge, as well as an enthusiasm for life. Her gentle character and deep religious beliefs were obvious and I wished I had met her before this day, my last in Nebraska.