text:
Race and Gender in Doctor Who: Don't Get Your Hopes Up
By Keidra Doctor Who gender and sexuality race and ethnicity
So, OK. Did anyone really think that we'd have a non-white male Doctor this time? Really? Because if you did, I salute you because you definitely have more hope for the present day pop-culture powers that be than I do.
Let me preface this by saying, I have no qualms with the choice of Peter Capaldi as the Doctor, I actually don't know very much about him as an actor, and I'll never know about his performance in World War Z because I have an aversion to zombies. I'm not touching that film. Honestly, I am impressed that the Doctor is over 50, I was never expecting to see that again, considering the trend towards younger and younger actors as the Doctor helped to make the show more palatable to teens and to those who may have been turned off by the old school "grandpa or weird old uncle" vibe of Doctor Who. I honestly, sadly think a 55-year old Doctor is a bold move in the post-RTD/Moffat era. (And yes, I know we've had young-ish Doctors in the past.)
But despite the speculation, petitions and general outcry, I never really expected a female doctor to happen, and I honestly don't expect it to happen for a long time. We may see a non-white Doctor, and it's rumored we might have gotten it this time around, if Neil Gaiman is to be believed. I suspect the guy in question was Idris Elba, and if that was the case he made a good choice. He's like Britain's Will Smith. He has his sights for something bigger (and if those sights include a Pacific Rim prequel along the way I WILL TAKE IT.)
But the fact is, a woman Doctor with Moffat as showrunner is not gonna happen, and even if it did happen, it would probably suck. We've written about Moffat's lady issue on TLF before.But even if he did decide to cast a woman as the Doctor, I am sure he'd have her knocked up by mid-season or following her male companion around all WHY WON'T YOU MARRY ME. He can't write women without throwing marriage and babies because it's all we live for, you know. Or, even worse, he'll have a woman doctor and a woman companion and it will just be Bechdel Test FAIL in every episode as they fight and sigh over random guys they meet and fret over their biological clocks.
When it comes to race and Doctor Who it's equally complicated. And this complication isn't limited to Doctor Who, or sci-fi, or television. The fact is when it comes to television in general, white males are the assumed default, which is a DUH considering that white guys are 98% of the showrunners, producers, and writers of these shows. Until the pop-culture collective lens acknowledges that universality of life experience is not the sole domain of white guys, we'll always get white guys in these iconic roles defining said experiences. And the only way that is going to happen is through more non-white guys getting their stories told in television and film.
And let's face it Doctor Who (like most science fiction shows of its ilk) a long history of stories that reflect a very Eurocentric and colonialist cultural perspective of going around to different worlds, times and cultures and telling them What's Best For Them. Not just Doctor Who mind you, so don't get your panties in a twist, you can see it in show's like (early) Star Trek as well. Feel free to nitpick the finer points of Who or Trek all you want, to me, this is about the collective, historical failure of the television industry as a whole.
But in contemporary Who, we have Martha! Yay Martha! She got to go back in time and be a maid! (Wait…)
Oh yes, and Mickey, issue's of race were not really a part of Mickey's story in any way, though you could argue that shoehorning a relationship with Martha at the last minute in that awkward way that some white people like to play matchmaker with their only two black-opposite sex friends YOU KNOW IT HAPPENS was all about race. But – and I am going to presume at this point that there aren't any writers of color on staff with Doctor Who – imagine if there were, and how characters of color and their lived experiences and their histories and their perspectives may be integrated in a way that doesn't seem peripheral. I had hope during the Russell T. Davies years, because there were scenes in his underrated Queer As Folk that made me think he got it, on a surface level with the black female character of Donna (he LOVES to reuse names, that RTD) but it never happened, when the time came. His stories put women and people of color in the same box of character periphery.
So while I am so on board for a woman Doctor or a Black doctor or OMG an Asian doctor HOLY CRAP CAN YOU IMAGINE, I am even more on board for a shift in Doctor Who's storytelling overall, a perspective that isn't rooted in the perspective and history of presumed whiteness, presumed maleness. That is when we will really see some progress.
Michelle Scott
I'm admittedly excited about this new Doctor fella, because honestly–Smith just didn't work for me past his first season.
But, on another note…if one wants to talk about the racial implications of this show, it only takes going back to the early DW years to see some fairly serious racism in action on the screen. Just because it's no longer as blatant doesn't mean it's good or right in its current incarnation. They still have a long way to go.
WORD to everything you wrote (and I couldn't care less about Doctor Who). Also, check out Peter Capaldi in the film "In the Loop." He plays foul-mouthed political strategist Malcolm Tucker, which made him a semi-star in the UK (the film is actually a spinoff of the UK TV show "The Thick of It," in which Capaldi originated the character. Both TV show and film were created by Armando Iannucci, the guy behind the HBO series "Veep").
Okay. I'm done now.


text:
The Stars Group Gaming Vendor Information
Amaya secures online gaming license for the Dominican Republic
MONTREAL, Canada -- (PRESS RELEASE) -- Amaya Gaming Group Inc., an entertainment solutions provider for the gaming industry announced today that it has secured a license to operate online gaming in the Dominican Republic. The Dominican Republic is the second largest Caribbean nation with an estimated population of 10 million people.
Amaya's online gaming offering includes slot games as well as table games like Blackjack, Roulette, Sicbo, Craps and Baccarat in addition to peer-to-peer games such as online poker. The online gaming site is expected to be launched by Q3 2011.
"We are extremely pleased to have secured this license to operate online gaming in the Dominican Republic. We believe our extensive gaming library and technological capabilities have been key deciding factors in securing this license. As one the fastest growing segment of the entertainment industry, online gaming still represents a significant untapped market segment for Amaya" mentioned Mr. David Baazov, President and Chief Executive Officer of Amaya.
Commenting on the granting of the online gaming license, Mr. Conrado Abud, Director of Casinos for the Ministry of Finance of the Dominican Republic said "Based on our investigations and due diligence, we have decided to authorize Amaya with the only license of its kind to operate online gaming in the country. As such, this is a sector of the gaming industry that is rapidly developing in an illegal way. Amaya was granted the license to redirect this already existing but illegal gaming activity to a site that is secure, legal and trustworthy."
Amaya secures online gaming license for the Dominican Republic is republished from iGamingNews.com.

redpajama_set_name: RedPajamaCommonCrawl


text:
O condado de St. Lucie () é um dos 67 condados do estado americano da Flórida. A sede do condado é Fort Pierce e a localidade mais populosa é Port St. Lucie. Foi fundado em 14 de março de 1844.

Geografia
De acordo com o United States Census Bureau, o condado possui uma área de , dos quais  estão cobertos por terra e 301 km² por água.

Demografia

Segundo o censo nacional de 2010, o condado possui uma população de  habitantes e uma densidade populacional de 187 hab/km². Possui  residências, que resulta em uma densidade de 92 residências/km².

Das três localidades incorporadas no condado, Port St. Lucie é a mais populosa, com  habitantes, enquanto Fort Pierce é a mais densamente povoada, com 781 hab/km². Saint Lucie Village é a menos populosa, com 590 habitantes. De 2000 para 2010, a população de Port St. Lucie cresceu 85% e a de Saint Lucie Village reduziu em 2%. Apenas uma localidade possui população superior a 100 mil habitantes.

Ligações externas

redpajama_set_name: RedPajamaWikipedia


Angelina Jolie's life has always revolved around humanitarianism. Her works in developing countries such as Cambodia is commendable – a country she not only holds citizenship in, but a country where she adopted her son, Maddox Chivan from an orphanage in 2002. Since then, Jolie has returned to Cambodia to begin a film production based on Loung Ung's memoir, First They Killed My Father. It tells a story from a child's perspective through her blurred memories and recollections as Ung suffered and survived through the Khmer Rouge. The film depicts a real life event and seeks the convey the emotions and terror of war through a child's eyes. However, a controversy arose when rumors and allegations circulate how Jolie and the casting crew toyed with children's psychological and emotional well-beings during the audition process.
Jolie and the casting team's intentions have always been to shine light on the horrors the Cambodian men, women, but most importantly the children faced during the war – a Cambodian genocide that resulted in a eradication of two million people by the Khmer Rouge. Despite the false accusations by critics towards Jolie and the casting directors, Srey Moch will play Loung Ung as she attempts to show the world through a child's view and how she escaped the turmoil of life in the Killing Field.
Albeit, there is always a level of skepticism when a foreigner goes into a country to make a film about an event that so many Cambodians were affected by. Many of you might be asking, "Why Angelina Jolie? Why is she telling the one and only story where neither herself or her parents suffered through?" Jolie is ambitious, but has enough humility to be cognizant of the fact that even though it is not her story, she is helping to tell a story as a team with Ung and Panh. To those unfamiliar with Cambodia and its bleak history, this film serves as an invitation to watch as it premieres on September 18th on Netflix. The visual creativity is guaranteed to invoke tears, laughs, but most importantly, hope.
Sreymich is a sophomore Neuroscience major from California! You can most likely catch her staying active, learning how to play the guitar, or watching BTS live performances on YouTube!


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TX: Constitutional Carry Bill HB 375 Filed
Posted by Emma Wolff on Dec 2, 2016 in Constitutional Carry, Featured, Legislation | 0 comments
Many people view Texas as an extremely gun friendly state. Texas has been becoming gun friendly, but the image has not been entirely deserved. The Texas Legislature only restored partial open carry rights last year, after banning most open carry for a hundred and thirty years after Reconstruction. Open carry still requires a permit from the state. The permit fee is $140, putting it out of the reach of many people. State Representative Jonathan Stickland wants to change that. From caller.com:
"It's time in Texas to restore our Second Amendment rights to their originally intended level," said state Rep. Jonathan Stickland, a Fort Worth-area Republican who last year spearheaded the successful open-carry bill.
This time, Stickland is the chief author of legislation supporters call "constitutional carry." Unlike the open-carry bill, the new measure does not require a license — or the passing of a gun-safety test and the payment of a $140 fee for the license — to allow a handgun to be carried either openly or concealed.
Stickland, who will begin his third two-year term when the Legislature convenes Jan. 10, pushed hard for a similar bill in 2015 but lawmakers were unwilling to go that far. This year, Stickland has a well-placed ally for at least addressing the license fee.
That ally is Lt. Governor Daniel Patrick. Lt. Governor Dan Patrick has been a staunch Second Amendment supporter in Texas. He is enthusiastically pushing to reduce the fee for the Texas Concealed Handgun License.
"Texas has one of the highest license-to-carry fees in the country," Patrick said. "No Texan should be deprived of their right to self-protection because of onerous licensing fees imposed by the state."
There is a lot of Texas legal code concerning the carrying of handguns and weapons. Strickland's bill has to deal with that, so it is fairly long. The bill is H.B. 375. Here is one of the key provisions of Stickland's bill. From state.tx.us:
Subsection (k) to read as follows:
(k) Notwithstanding any other law to the contrary, a person who is not otherwise prohibited by law from possessing a firearm shall not be required to obtain any license to carry a handgun as a condition for carrying a handgun.
Eleven other states already have permitless or "Constitutional" carry. Texas is not breaking any new ground. Constitutional carry is already working well in other states. Strickland's bill has a shot. Four states passed Constitutional carry last year, in 2016. Those states were Idaho, Mississippi, West Virginia, and Missouri. Several other states are considering removing infringements on the carry of arms in 2017.
It is not clear if there is sufficient public pressure in Texas to remove the infringement of a license to carry in 2017. In 2015, I predicted that open carry would pass, and that campus carry might pass. The Texas legislature passed both.
Here is a prediction for 2017. Constitutional carry may not pass, but the license fee will be reduced. It is an incremental step toward "Constitutional" or permitless carry. Before Reconstruction, Texas had the strongest right to bear arms amendment of any state in the United States. In Texas, even slaves had the right to keep and bear arms, as affirmed by the Texas Supreme Court in 1859. The decision was Cockrum v. State.
High permit fees chill the right to keep and bear arms. John Lott has noted that the more a permits costs to acquire, the lower the percentage of people who acquire them. A lowered permit fee is a move toward removing an infringement on the Second Amendment.
©2016 by Dean Weingarten: Permission to share is granted when this notice and link are included.
Gun Watch
Texas Governor Greg Abbott Explains Why Texas Gun Laws Give Advantage to Students in Case of Attack
Issue of guns on Missouri campuses may come up again
Local Criminal Law Firm Explains What You Need to Know About Texas' New Open Carry Laws.
2A WIN: This State Just Reinstated Their Citizens' Freedoms
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text:
Brett Kavanaugh: Key moments in his testimony, including his furious and emotional response
WASHINGTON - Supreme Court nominee Brett Kavanaugh offered emotional testimony Thursday about what a "circus" his confirmation process has become and denounced the sexual assault allegations that have "destroyed" his name.
Kavanaugh's testimony came directly after about four hours of testimony given by Christine Blasey Ford, who alleges he held her down and tried to remove her clothes at a party in 1982 when they were both in high school.
Kavanaugh used his opening statement to both attack Democrats who he says are targeting him and refute all of the particulars of the allegations lodged against him.
Here are some of the most powerful moments from Kavanaugh's testimony:
'You will not drive me out'
Kavanaugh started his testimony filled with anger and a message for Democrats.
He accused liberals of using the accusations lodged against him as a "political hit," explaining the opposition to his was tied to the opposition to President Donald Trump.
He angrily called out Democrats for comments they'd previously made over the confirmation process, painting him as "evil" and America's "worst nightmare."
"It was designed to scare me," he said. But that wouldn't work.
Kavanaugh then directed his message to Democrats: "You tried hard. You've given it your all."
But, he added, "your coordinated effort" to "destroy my name and my family" will not work.
"You will not drive me out," he said.
He continued: "You may defeat me in the final vote, but you'll never get me to quit."
Breaking down in tears multiple times
Kavanaugh gave an emotional testimony, much different than the hours and days of testimony he'd given previously. He described his family, how these allegations had destroyed his life and how the effects of this process would ripple on forever.
He talked about his two daughters, Margaret and Eliza, and his wife Ashley.
"I intend no ill will toward Dr. Ford," Kavanaugh told the committee, starting to break down in tears. "The other night, Ashley and my daughter Eliza said their prayers, and little Eliza, all of 10 years old, said to Ashley, 'We should pray for the woman.' That's a lot of wisdom from a 10-year-old."
He paused, tried to contain his emotions, then said, "We mean no ill will."
Kavanaugh broke down other times, including when he spoke of his childhood friends who have been forced into the spotlight and those who have stuck up for his reputation.
Confirmation process has become a 'circus'
Both Republicans and Democrats have admitted the confirmation process has been unfair to both Kavanaugh and Ford, whose personal lives have been cast in the spotlight.
"This confirmation process has become a national disgrace," Kavanaugh said with anger. He continued, focusing on the many conspiracy theories and "crazy" accusations that have surfaced, including him being in a gang and being the father to a secret child.
"This whole two-week effort has been a calculated and orchestrated political hit fueled with apparent pent-up anger about President Trump and the 2016 election," he told the committee. "This is a circus."
Kavanaugh told the committee it won't be just his confirmation that is affected by this chaotic process.
"The consequences will extend long past my nomination," Kavanaugh said. "The consequences will be with us for decades. This grotesque and coordinated character assassination will dissuade competence in good people of all political persuasions from serving our country."
Kavanaugh said his life has been changed forever because of these allegations and how they were handled by the committee.
"I may never be able to teach again," he said, adding he might not be able to continue coaching his daughter's basketball team.


Petra Pan Film Production is a Slovenian film production company founded in 2003. The company produces creative documentaries and art house fiction films for the international market. Petra Pan is a dynamic and ambitious international group of people focusing on a strong author's signature and a high artistic profile in every field of filmmaking. Aiming to produce a high quality innovative program beyond the norms of documentary film and communicating our vision on the world around us. Our production policy is to work together with our long term partners and be part of the multinational production network with the same motivation and goal.


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Heather Hachigian
Dr. Heather Hachigian is an assistant professor teaching in the Masters of Global Management Program and the Graduate Certificate in Corporate Social Innovation. Her research interests include responsible investment, social finance and new forms of organizations. Hachigian's recent work focuses on the governance of investment institutions with an explicit long-term mandate. Her research has explored investment decision-making under ambiguity, shareholder engagement and integrating sustainability criteria into infrastructure investment deals. Hachigian has published her research in several book chapters and academic journals, including Business and Politics, Journal of Sustainable Finance and Investment, Journal of Business Ethics, European Financial Review and Stanford Social Innovation Review.
Hachigian previously worked as a senior consultant with Purpose Capital. She provides research and advisory services to government, business and non-profits on impact measurement, social finance and sustainable investing. Recent projects include an evaluation of social finance models for migrant and refugee integration and a retail impact investing guidebook. Hachigian has served as a judge for the annual Responsible Investor Reporting Awards and an editorial board member for Journal of Sustainable Finance and Investment.
University of Oxford's Smith School of Enterprise and the Environment
Master of Public Administratio
Bachelor of Arts with Combined Honours in Economics and Political Science
Hachigian, H. (2020). Review of The Code of Capital: How the Law Creates Wealth and Inequality by Katharina Pistor. Journal of Business Ethics, 166(1), 197-201.
Hachigian, H. (2018). Understanding the governance structures that underpin responsible investment decision-making. In Deborah C. Poff and Alex C. Michalos (eds.) Encyclopedia of Business and Professional Ethics. Springer.
Hachigian, H. (2017, April). Understanding Under-investment in Migrant Integration. European Financial Review.
Hachigian, H. (2016, September). Investing in Global Refugee and Migrant Integration. Stanford Social Innovation Review. September 21, 2016.
Harji, K., Hachigian, H. and Jeyaloganathan, M. (April 2016). Retail Impact Investment Guidebook for Credit Unions. Prepared for Canadian Credit Union Association and ESDC.
Hebb, T., Hachigian, H. and Harji, K. (January, 2016). Social Finance Models for the Settlement and Integration Sector in Canada, Market Assessment Report. Prepared for Immigration, Refugees and Citizenship Canada.
Hachigian, H. (2015). Ambiguity, discretion and ethics in Norway's sovereign wealth fund. Business and Politics, 17(4), 603-631.
Clark, G. L., Hachigian, H., McGill, S., Molinari, C., & Wójcik, D. (2015). Addressing the challenges of transformation through sustainable investment. In The Routledge Handbook of Responsible Investment (pp. 617-633). Routledge.
The market, Main Street and the common good
Business doesn't just have to be about dollars and cents, says Dr. Heather Hachigian. It can be about change too – social change that is.
Faculty Research Business
RRU study looks to save small businesses from 'succession cliff'
Assist. Prof. Heather Hachigian receives $280,000 from Vancouver Foundation for Testing Impactful Successions at Scale research project.


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Fujikura's MCI shaft
By James Achenbach January 21, 2014 11:30 am
By James Achenbach | January 21, 2014 11:30 am
A Fujikura golf shaft played a large part in one of the longest – if not, the longest – drives hit last year.
Tim Burke, 26, used Fujikura's FlyWire shaft to blast a 427-yard drive to win the Re/Max World Long Drive Championship in Las Vegas.
There was no wind, so the winning drive was totally legitimate. Burke, a former pitcher at the University of Miami, was swinging a Krank Formula 5 driver with 3 degrees of loft. Krank, headquartered in Tempe, Ariz., specializes in long-drive driver heads. Burke's FlyWire shaft, which weighed 54 grams, is made specifically for Krank and designed for golfers with high swing speeds.
Most golfers are not strong enough or fast enough to swing the FlyWire, but another Fujikura development has the potential to catch golfers' attention.
Fujikura's MCI (Metal Composite Iron) shaft recently became widely available through the certified network of Fujikura dealers. This iron shaft is a blend of graphite and steel. The objective is better balance, feel and stability.
Fujikura will bring a new MCH shaft for hybrids to the PGA Merchandise Show this week in Orlando, Fla. This shaft also mixes graphite and steel.
Steel and aluminum have been mixed with graphite, or composite material, for more than 20 years in golf, but Fujikura possesses a process patent for its method of combining graphite and steel. This is not simply a procedure of adding steel strands to graphite shafts. It is a complicated operation.
Other companies with successful products that combine graphite and steel include Aerotech and Callaway.
Aerotech's SteelFiber shaft employs steel mesh over a graphite core. Matt Kuchar and Brandt Snedeker have won with this shaft on the PGA Tour.
Callaway, with its Fusion process, has accomplished cutting-edge design in joining graphite with titanium in its driver heads.
At the same time, it needs to be recognized that all-graphite iron shafts have improved dramatically in the past few years. Aldila's RIP shaft was used by two tour winners in 2013 (Boo Weekley and Ken Duke), and UST Mamiya's Recoil shaft has captured the attention of several touring pros, most notably Ernie Els.
Manufacturers have overcome two longstanding concerns with graphite iron shafts: One, old designs often felt so light that skilled players had a difficult time sensing the clubhead during the swing; two, graphite shafts, despite their legendary ability to dampen vibration, often felt clunky or boardy at impact.
Welcome to a new era of graphite iron shafts and graphite/steel combo iron shafts. For Fujikura, the Metal Composite story is one of weight distribution and balance. Weight has been moved from the butt end of the shaft to the tip end.
"MCI has the balance (point) down in the lower end of the shaft," said Dave Schnider, Fujikura chief operating officer and president. "That way there is no feel issue. Nobody is going to say the shaft feels too light, which has been a common complaint about graphite iron shafts."
MCI is not a shaft that promises more distance. As mentioned earlier, it's about balance, feel and trajectory. Because graphite can be adjusted easily and manipulated in the design process, emphasis can be placed on getting the ball up in the air with long irons.
MCI is available in four weight categories: 60, 80, 100 and 120 grams. Swingweights will end up in same range as steel. The suggested retail price is $100 apiece for the 60 and 80 models, $115 for the 100 and $150 for the 120.


text:
# hgrep
[![Travis Build Status](https://travis-ci.org/thumphries/hgrep.svg?branch=master)](https://travis-ci.org/thumphries/hgrep)
[![AppVeyor Build Status](https://ci.appveyor.com/api/projects/status/2xmkp3jbt1q078xv/branch/master?svg=true)](https://ci.appveyor.com/project/thumphries/hgrep)
[![Hackage page (downloads and API reference)](http://img.shields.io/hackage/v/hgrep.svg)](http://hackage.haskell.org/package/hgrep)
[![Hackage-Deps](https://img.shields.io/hackage-deps/v/hgrep.svg)](http://packdeps.haskellers.com/reverse/hgrep)

Search Haskell source code from the command line.

Powered by ghc-exactprint.

## Usage

```haskell
$> hgrep
Usage: hgrep [-e|--regex] EXPRESSION [FILE]
```

`hgrep` requires an expression and a set of files to search across.

An expression can be one of
- The name of a type, e.g. `FooBar`
- The name of an expression, e.g. `foo`
- A regular expression (via the `-e` flag), e.g. `-e Foo$`

Each file will be parsed and searched. Results will be printed to the
console, with syntax highlighting where possible.

### Requirements

You can use `cabal` or `stack` to install, but you may need `libpcre`. In case you don't have it:

#### Ubuntu

```bash
sudo apt update
sudo apt install libpcre3-dev
```

#### Fedora

```
sudo dnf update
sudo dnf install pcre-devel
```

#### NixOS / Nix Package Manager

```
nix-env -i pcre
```

### Install

#### Stack

```
git clone https://github.com/thumphries/hgrep.git
cd !$
stack install
```

#### Cabal

```
git clone https://github.com/thumphries/hgrep.git
cd !$
cabal new-build
```

#### Mafia

```
git clone https://github.com/thumphries/hgrep.git
cd !$
mafia build
```

#### Nix
```
git clone https://github.com/thumphries/hgrep.git
cd !$
nix-build -E 'with import <nixpkgs> {}; haskellPackages.callCabal2nix "hgrep" ./. {}'
```

### Searching for top-level expressions

```haskell
$> hgrep main main/hgrep.hs
main/hgrep.hs:16:1-13

-- | Run the program.
main :: IO ()
main/hgrep.hs:(17,1)-(18:27)

main = do
  putStrLn "Hello, world!"
```

### Searching for type declarations

```haskell
$> hgrep PrintOpts src/**/*.hs
src/Language/Haskell/HGrep/Internal/Data.hs:(40,1)-(42,28)

data PrintOpts = PrintOpts {
    poColourOpts :: ColourOpts
  } deriving (Eq, Ord, Show)
```

### Searching with a regular expression

```haskell
$> hgrep -e 'Opts$' src/**/*.hs
src/Language/Haskell/HGrep/Internal/Data.hs:(57,1)-(59,28)

data PrintOpts = PrintOpts {
    poColourOpts :: ColourOpts
  } deriving (Eq, Ord, Show)
src/Language/Haskell/HGrep/Internal/Data.hs:(61,1)-(64,26)

defaultPrintOpts :: PrintOpts
src/Language/Haskell/HGrep/Internal/Data.hs:(67,1)-(70,5)

defaultPrintOpts =
  PrintOpts {
      poColourOpts = DefaultColours
    }
```

redpajama_set_name: RedPajamaGithub


When it comes to my blog and business, I'm often asked why I haven't hired anyone to take over part of what I do — or to do all that "boring stuff" like social media, email newsletters, proofreading, editing, etc.
Unfortunately, I don't have a super simple answer for these questions… but today, I'm sharing approximately 1500 words as to why I'm still doing it all myself after almost 8 years!
However, I've been working hard at "letting" myself splurge on more quality items here and there — and today, I'm sharing what items I'm more willing to splurge on, what items I still prefer to save on, and how I make my choice either way.
I shared a picture of these French Toast Sticks on Facebook a couple weeks ago and immediately started getting questions about what they were, how I made them, if there was a recipe, etc. etc.
I realize that I've talked a lot about digital photo storage and organization — and I know I've mentioned Flickr before. But I don't think I've ever gone into detail about how Flickr truly does make my photo organization SO much simpler and easier.
So that's what I'm going to talk about today — and for the record Flickr offers tons of safe, online photo storage to everyone totally FREE!!
In case you missed my first announcement (which it seems like many of you did) and the several more casual references to "baby #3" here on my blog and social media, I'm pregnant — AND the baby is over half way "cooked"!
What do you think… is it a boy or a girl?
You Won't Believe How We Finally Got Nora to Sleep!
I remember "way back when" Nora was just an infant and I hadn't slept more than a couple hours in days. I was SO tired, SO exhausted, and SO frustrated. By her 2nd birthday, I started wondering if we'd ever sleep through the night again. I told myself that "someday, when she finally started sleeping through the night, I would write a blog post about everything we tried." So today, I'm more than just a little excited to FINALLY be writing that blog post… and yes, she is sleeping through the night!!!!
I've always LOVED making my own bread… I love the feel of the dough between my fingers, I love the smell wafting from the oven, and of course, I love the taste of it. However, after Nora was born, I just stopped making the time for bread baking.
Since then, I have come up with a super quick, super easy, nearly fool-proof way to enjoy homemade bread with almost no effort… as of today, my "secret" is out!
I canned 36+ quarts of applesauce this weekend! Yes, you read that right… Valentines Day weekend.
It might sound crazy to be canning in the middle of winter IN MICHIGAN! But that's usually how I do it because that's when I have the time and that's when I'm cooped up inside anyway! Am I the only "crazy" one??
I think marriage (and really any relationship) takes a lot of hard work — and good relationships don't just happen because of one romantic gesture.
So while surprise, over-the-top romantic gestures are certainly welcome in almost any marriage, I think it's often the every-day real life events that feel the most romantic when done day after day after day. Don't you?
A couple weeks ago, I was in the mood for my favorite chicken and rice soup. The only problem was, I had about 2 Tablespoons of rice left with no back-up bag… and I realized this around 4:30pm.
So after quickly scrambling to come up with a new recipe, I decided on chicken noodle soup — and within 30 minutes, we had homemade, from scratch, chicken noodle soup on our table!
Over the past few years, I've written many posts about WHY I plan ahead — to save time, money, stress, etc. etc. However, if you think about it, the "WHY" of planning ahead is relatively obvious. It's the "HOW" of planning ahead that is the road-block for so many people.
So while I know my methods won't work for everyone, today I'm sharing HOW I plan ahead in many different areas of my business and personal life.
As a life-long lover of cleaning, organizing, and all things "home", I've heard my share of negative comments geared at my "perfect home". Sometimes, I've even felt ashamed of doing my 'one thing' really well.
If you've ever felt ashamed of doing your 'one thing' well (whatever that one thing is) read this post!
I know, I know… it's already the first week of February and I'm just finally getting around to sharing my 2015 goals.
I have another really fun giveaway today — just in time for a little Valentine's Day treat for ourselves!


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The next municipal and school board election will be happening in 2020, but not on the date that was initially scheduled.
The provincial government announced last week that it had moved its next provincial election to Oct. 26, 2020.
The municipal and school board election will instead happen on Nov. 9 of that year. It's going to be on a Monday, as opposed to the traditional Wednesday date, because Remembrance Day is on a Wednesday in 2020.
There had been discussion of having the next civic election in 2021, but those plans appear to have been abandoned.
Mayor Roy Ludwig said local city council gave the issue some thought, and said previously they would grudgingly back a five-year term.
The mayor believes other municipal governments in Saskatchewan were opposed to the change.
"I know quite a few of the larger cities especially did not agree with it," said Ludwig.
He also found out about the government's decision through the media.
Ludwig would have rather seen the provincial government keep the civic election on its original date of Oct. 28, 2020, and to see the province have an election in September or November.
City clerk Judy Pilloud also voiced a few concerns with the new election dates. The first is that the majority of election workers are snowbirds who are usually gone by the date the provincial government has selected for the municipal election.
Another concern is the city budget. It is usually completed in the last week of November, and if a new council is being sworn after Nov. 9, they will need time to understand what the city does operationally.
Pilloud conceded the new council will be elected only 12 days later than expected, but by the time they're declared elected and sworn-in, it won't leave much time for the budget.
If a second call for nominations is needed for mayor, councillor or school board trustee, then it pushes the date of the vote even closer to Christmas.
Other cities have found themselves in situations in which they haven't had enough candidates for an election.
She is also concerned about the effects of having the elections so close together, because the rules and regulations are so different between the province and municipal elections.
"That's when people get confused on what requirements are for voting," said Pilloud.
The city doesn't enumerate, unlike provincial and federal governments, and she is worried people will think the procedure for voting in the civic election will be the same as federal or provincial.
In a news release, Premier Scott Moe said he received a clear message from municipalities and school boards about a desire to keep the civic election in 2020.
"We believe we have reached a reasonable compromise that will allow local officials time to prepare for these changes," said Moe.
As for the school boards, Saskatchewan School Boards Association president Shawn Davidson said the association is pleased election dates have been chosen.
Moe noted that in 1991 and 2003, the municipal and provincial elections were held about two weeks apart. He said the government decided to have the provincial election first because moving the provincial election back would make it difficult, if not impossible, to hold a fall legislative session before Christmas.


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The focus on gaining or losing an hour of sleep in the spring and fall tends to overshadow the bigger issue of chronic sleep disorders, which is becoming increasingly a problem as electronic devices keep us up later and other poor health habits persist, according sleep experts.
"Daylight saving time" (DST) ended officially Sunday at 2 a.m. The "fall back" time of year means we gained an extra hour of sleep. The yearly time shift serves mainly as a reminder of bigger issues for those who suffer some degree of a sleep disorder. Disrupted sleep cycles — or just not getting enough sleep — can contribute to being overweight and worsen chronic conditions such as heart disease, diabetes and depression.
Every patient's sleep disorder is unique and requires specialized attention. But there are a few factors that contribute to common disorders fueled by a lack of sleep, from insomnia to occasional sleep disruptions, says Timothy Grant, M.D., the medical director of Baptist Sleep Center at Sunset.
Hectic work and family schedules during weekdays fuels the popular practice of "sleeping in" on weekends, or sleeping later than usual. But even that break in the routine, which may seem beneficial, may actually contribute to chronic sleep problems, says Dr. Grant, who is a neurologist and Fellow of the American Academy of Sleep Medicine.
There are other somewhat surprising factors — including caffeine consumption early in the day, mid-day naps and exercising late in the day — that can disrupt sleep patterns and contribute to insomnia or intermittent sleep disruptions, says Dr. Grant.
"A lot of things have caffeine and people don't know it," he says. "Like energy drinks that people consume during the day. And as you get older, sometimes caffeine can have an effect on you 10 hours later. So you can have a cup of coffee with your lunch, and it can keep you up later at night. Again, that depends on the patient.
As is generally accepted, regular exercise prolongs life and can help treat or prevent heart disease, diabetes and some cancers. But the time of exercise routines should be carefully planned.
Stick to a sleep schedule. Keep the same bedtime and wake-up time, even on the weekends if possible. This routine helps to regulate your body's clock and could help you fall asleep and stay asleep for the night.
Practice a relaxing bedtime ritual. A quiet and calming activity, such as reading, right before bedtime is best achieved away from bright lights to help separate sleep time from activities that can cause excitement, stress or anxiety. For this reason, computer screens of any size should be avoided just before going to sleep.
Disconnect. Turn off TVs and computers, and put down tablets and cell phones, two hours prior to going to bed.
Avoid mid-day naps, especially in the afternoon. So-called power napping may help you get through the day, but if you find that you can't fall asleep at bedtime, eliminating even short naps can help.
Exercise daily. Moderately intense exercise is best, according to the American Heart Association, and light exercise is better than no activity, but refrain from exercising in the four hours before going to sleep. The first signal that the body is ready to go to sleep is body temperature. Exercise raises body temperature.
Evaluate your room. Design your sleep environment to establish the best conditions for sound sleep. Your bedroom should be comfortably cool and free from any noise or light that can disturb your sleep.
Sleep on a comfortable mattress and pillows. This may sound obvious, but it's important. Make sure your mattress is comfortable and supportive. The one you have been using for years may have exceeded its life expectancy – about 9 or 10 years for most good quality mattresses. Comfortable pillows are also important.


text:
A Critical Analysis of Ariana Grande's Music
Reed Wilson
ariana grande,
music videos,
song lyrics,
tabatha lewis
Post by Tabatha Lewis
There is no doubt that Ariana Grande is an insanely talented singer. She has proven her vocal prowess on Saturday Night Live, imitating singers such as Shakira, Céline Dion, and Rihanna. However, I would argue that her song lyrics and music videos are lackluster and cliché. She leaves the audience wondering whether she is empowering women's sexuality or inviting them to have sex with her through their computer screens.
One of her hit songs last year was "God is a Woman." With such an enticing title, there is a hope that the song will empower women to some extent, as it plays with the idea of God being historically viewed as a male entity—depending on the religion and one's own perception of gender, what does God having a gender even really mean? Yet the way the audio and visual effects of "God is a Woman" are interwoven makes me feel as if I'm watching a blurred out porno. In one of the scenes we see Ariana slathered in paint, conveniently covering her nipples. In all her sexual prowess, why does she insist on conforming to society's discomfort about seeing female nipples, when masculine nipples are a common sighting. I feel much more empowered as a woman watching Cardi B's "Money" music video in which women's breast are unashamedly shown, and Cardi B herself is shown breastfeeding in the music video. "Money" promotes women's sexuality and power more than "God is a Woman" by bravely straddling the line of what it means for a woman to show her body as it is, rather than as a sexualized object, waiting to be viewed on the internet.
Additionally, the lyrics in "God is a Woman" mirror the artistic vision of the music video. The lyrics produce this message that women draw their strength from their ability to please men/women. Exemplified in the opening line, "You love it how I move you, You love it how I touch you," and another lyric,"have it any way you like." Each sets up the dynamic of Ariana pleasuring another, which is a misguided attempt at showing off a female/male's prowess. As someone who identifies as a female, my strength doesn't come from my ability to pleasure a male, it comes from my ability to succeed at any task I put my mind to. My sexual appeal is an amalgam: of looks to an extent, intellect and character, but certainly not the way I can make a male feel with my body. Properly worded, this song could have empowered women yet by focusing on pleasuring another being it made woman the physical equivalent of a sex doll.
Her newest music video "Thank u, next", was hugely popular. While amidst this massive crossover of the most well-known "Chick Flick" films available, Ariana Grande relates a positive message of thanking, not bashing on, her ex-boyfriends for the things she's learned from and experienced with them. The use of iconic, albeit basic, movies in the music video certainly helps broadcast its message as it attracts the attention of its target audience. While the message is clear, and is one that modern day youth should process, the writing of the lyrics itself leaves much to be desired; most of them are unnecessary and repetitive. Half of the lyrics are the song title itself, some name drops and then a few lyrics regarding lessons about patience and love. Making popular music with simplistic lyrics is an insult to many other great artists, like one of my personal favorites, Twenty-One Pilots, who have complex lyrics and themes behind their songs.
The importance of lyrics in music varies in magnitude depending on the genre. For example, in electronic dance music (EDM) or classical music, the lyrics are not essential to the music, whereas the beat and all of the accompanying sounds are placed at the forefront. On the other end of the spectrum is rap, where lyrics are crucial to the song. Pop music falls somewhere in the middle, making it a little more difficult to navigate. Artists can choose to have meaningless lyrics and tell their fans to "Shake it Off", or produce something quite personal and profound, like admitting to the fallibility of the human condition and the inability to break an addiction. That is the artist and their team's choice. Choosing the former, however, forgoes the artist's ability to shape society's perception of important issues, while the latter can be a tool to aid society in looking at a particular topic in a different light.
All in all, Ariana Grande's music and music videos conform considerably to pop cultures entertainment standards, as do many artists. However Ariana Grande is arguably a more talented vocalist than those artists. In my opinion, her voice belongs on Broadway where she can fully showcase her talent, not in music videos that falsely make women feel empowered when they are, in actuality, just being portrayed as objects used for pleasure. While she has incredible vocals she is not the best song writer, making a strong case for the idea that being an amazing singer does not a good writer make.


The Information Affairs Authority (IAA) is the government body in charge of the affairs of internal and external formal media in the kingdom, and supervises all media outlets, including newspapers, magazines, publications, radio and TV stations and websites. It has been presided by His Excellency Shaikh Fawaz bin Mohammed Al Khalifa since July 8th, 2010.
Achieving national interests and safeguarding national unity, security, stability and civic peace so as to ensure the continuity of the political and democratic reform march and economic development and protection of human right and basic freedoms, in a way that reflects the landmark strides attained during the prosperous era of His Majesty King Hamad bin Isa Al Khalifa, top IAA's priorities.
Achieving Media Excellence in the light of Bahrain Vision 2030.
(Creativity in quality organization and performance of the media in order to boost national identity and international position of the Kingdom of Bahrain and to enrich community knowledge and culture).
1- Credibility. 2- Freedom. 3- Fairness. 4- Competitiveness. 5- Sustainability. Values: 1- Respect. 2- Commitment. 3- Quality 4- Creativity.
Publish official news, information andstatements and cover official and local national functions and inform local andinternational public on them transparently.
Broadcast radio and televisionprograms that consolidate common national values and enhance the spirits ofcooperation and fraternity, so as to maintain the tolerant religious ethics andprinciples.
Support sustainable development efforts and consecrate the principles of democracy, human rights, reformation and portrayal of the government's foreign policy and its stances in various information media.
Develop the legislative infrastructure in thefields of press, publications and press and protect copy rights.
Propose media policies, strategies and implement them.
Grant licenses to private pressand media establishments, printing companies, publishing and distribution housesand NGOs specialized in media affairs.
Follow up local and foreign publicationscirculating in the Kingdom and monitor films and recorded publications in orderto ensure that they abide by the law and regulations, and do not violate publicorder or harm mor als, religions or sects.
Issue licenses to correspondents of foreignnewspapers, magazines, news agencies, radios and satellite TV channels to workin the kingdom and facilitate their missions.
Strengthen cooperation and newsexchange with foreign government bodies and media establishments.
Set up media centers and participate inpress conferences, inside and outside the kingdom.
Launch and organize specialized training andrehabilitation programs for human resources in the fields of press andmedia.
Encourage investments in the mediasector, in partnership with the private sector and leading foreign mediaestablishments.
Continue issuance of the (Official Gazette) which is the government's weekly newspaper comprising royal decrees, laws and ministerial regulations in addition to advertising, statements, official communiques, court rules. The official gazette was published for the first time in 1948 under the name of (Official News-Bulletin) before it assumed its present name in 1969.
Encourage and honor distinctive in various(traditional and electronic) newspapers and media in order to upgrade the media mission reliant upon professionalism and in compliance with Bahraini laws and international conventions.
His Majesty King Hamad bin Isa Al Khalifa issued, on July 8th, 2010, Royal Decree (31) for the year 2010, renaming the Culture and Information Ministry into the (Ministry of Culture) and establishing the Information Affairs Ministry (IAA), to be in charge of all media affairs stipulated in the Kingdom's laws and regulations. In Royal Decree (33) for the same year, HE Shaikh Fawaz bin Mohammed Al Khalifa has been appointed as IAA President with the rank of Minister.
Bahrain NewsAgency (BNA), the main source of official news and reports.
The number of newspapers in Bahrain has risen from 4 Arabic and English dailies in 1999 to 12 dailies and weeklies in 2012.
They are Akhbar Al-Khaleej (1976), Al-Ayam (1989), Al-Wassat (2002), Al-Watan (2005) and Al-Bilad (2008). Al-Meethaq (May 2004) and Al-Waqt (February 2006) stopped publishing due to financial reasons. Gulf Daily News (1978) and Daily Tribune (1997) are two English dailies.
A rise in the number of Bahraini TV channels to namely: the main channel, foreign channel, sports channel1, sports channel2, in addition to two channels namely: the Holy Koran and Bahrain International launched in December 2011 and work according to latest technologies of transmission and quality in order to meet viewers' aspirations.
A rise in the number of radio stations to eight radio stations namely: general radio Bahrain transmission, Holy Koran Radio, Bahrain FM, Shabibya Radio, Music Radio, Pop Music Radio, Hindi Radio, English Broadcast Radio (Radio Bahrain) in addition to voice transmission of Bahrain TV channel as well as foreign channel on Radio waves.
The amendment of law-decree number 47 for 2002 concerning the regulation of press, printing and publication so as to grant more freedom to journalism and media work.
A draft bill of law for the media to set up the Supreme Council for Press and Media which shall be an advisory council which gives its opinion regarding bills of law pertaining to media activity, preparation of research studies, follow up of financial reports of media and newspaper organizations, considers complaints, gives opinion on applications requesting issuance of licensure to establish or use media systems and organizations, or any official Bahraini media presence abroad.
A draft bill of law regarding the audio-visual media which organizes the rules and regulations pertaining to broadcasting and rebroadcasting of audio-visual programs, and the creation of the Audio-Visual Information Authority which shall acquire its corporate entity and shall be affiliated under the Minister both financially and administratively, and whose duty shall be to develop audio-visual media sector in the Kingdom and boost investments in it.
IAA is keen to improve the competence and performance of its staff through organizing various training courses and workshops, in cooperation with highly prestigious Arab and international media establishments for example with CNN, AOP, BBC, MBC, Reuters, TWofourt54, the French National Audio-visual Institute, etc..
IAA has always been committed to honoring distinguished works of active journalism and media. IAA President HE Shaikh Fawaz bin Mohammed Al Khalifa launched the Social Media Award 2012 in its first edition awarding prizes to the top 30 international social media users according to the following considerations, et alia: responsibility, creativity, contribution, confidence, credibility, compliance with professional ethics and morals. IAA intends to develop the award as from the year 2013 to cover throughout the GCC countries.
IAA paid a great attention to the activation of MoUs signed with foreign media corporations and organizations in addition to opening media attaché offices in a number of sisterly and friendly countries in the year 2011 namely: Egypt, USA, UK, France and Belgium, and developing organizational skeleton of the external media sector in IAA. Moreover, IAA organizes specialized forums and conferences in the field of journalism, the media and intellectual property, etc., in addition to significant developments which portray the true facts behind the actual situation, reform and development accomplished in the Kingdom at various regional and international functions.
In recognition of the Kingdom's achievements in terms of press and media freedom, His Majesty King Hamad bin Isa Al Khalifa received the Arab Media Creativity Award 2010 from the Arab Media Forum which coincided with the events of "Manama the Capital of the Arab Press for 2012" in the period 28-29 February 2012.
IAA's President HE Shaikh Fawaz bin Mohammed Al Khalifa inaugurated in June 2011 the authority's media strategy for the years 2011-2016. This step is considered the first of its kind in the history of the official media work and aims to improve performance and stimulate creativity to upgrade the media sector on scientific grounds.
IAA intends to carry out its strategy both professionally and competently whilst observant to the five principles for a responsible media business as follows: credibility, responsible freedom, fairness, competitiveness by stimulating creativity and sustainability by encouraging media investments and promoting all economically feasible activities.
IAA media strategy focuses on high values and principles regarding mutual respect, compliance with ethical and professional principles in conduct and job performance, quality assurance, encouragement of creativity and self-improvement, featuring spirit of cooperation, collective work, ensuring efficient, excellent job performance and institutionalization of the media field.
Achieving media quality in terms of organization, production and performance.
Improving technical quality by upgrading organizational policies, enforcing administrative, financial and technical procedures and upgrading the infrastructure.
Developing and stimulating human competencies to tap on creativity potentials and improve performance.
Providing and diversifying revenues to spur investments in the media field and rationalize the use of financial resources.
IAA is working on attracting international satellite stations and specialized media establishments in the media city set to be constructed after finalizing the needed legal and administrative procedures. It also seeks to promote local, Arab and foreign investments in the media field in partnership with the private sector and in conformity with the Economic Vision 2030.
IAA is strongly committed to building up an advanced media system that represents the cornerstone for sustainable political, economic and social development.


text:
Written by Isaac Orr | September 7, 2022
California on brink of blackouts two weeks after banning gas and diesel engines
On August 25, 2022, the California Air Resources Board (CARB) voted to ban the sale of new gasoline and diesel-powered engines for passenger vehicles by 2035. Two weeks later, on September 6, the state teetered on the brink of blackouts. Unfortunately, this situation could soon come to Minnesota.
Electric vehicles and grid reliability
California currently has a regulation called the Zero Emissions Vehicle (ZEV) rule, which requires auto manufacturers to stock a certain percentage of electric vehicles (EVs) or fuel cell cars in the state.
As a result of these regulations, EVs constituted 12 percent of the vehicles sold in California in 2021, and EVs made up 2.5 percent of all registered vehicles in the Golden State in 2021. As these regulations become more stringent in the future, the strain they place on California's unreliable electric grid will increase.
Reuters reports that the installed capacity on the electric grid would need to double by 2050 to accommodate a world where 66 percent of cars on the road are electric. This is bad news for California, which is already on the brink of blackouts, and will ostensibly hit the 66 percent mark before the rest of us.
California came very close to blackouts last night, with the California grid operator, the California Independent Systems Operator (CAISO), barely avoiding them by begging Golden State residents to reduce their power consumption.
#ISO declares an Energy Emergency Alert (EEA) 3. We have not called for rotating power outages yet. Read the news release: https://t.co/8Da4NXBBCS pic.twitter.com/lxo5XI0Zo9
— California ISO (@California_ISO) September 7, 2022
California is expected to struggle to keep the lights on tonight, as well. It will be interesting to see if they can stave off the blackouts until the heat subsides.
Minnesota's future
Minnesota's electric grid is also strained because too many electric companies have tried to replace reliable coal and nuclear plants with wind and solar. Now, the regional grid has a 1,200-megawatt capacity shortfall, enough to power about half the homes in Minnesota on an average hour.
Unfortunately, we seem destined to replicate California's failures, as Minnesota Governor Tim Walz has unilaterally adopted California's ZEV rules mandating automakers to stock electric vehicles in the state. It is important to note that these rules will not prohibit the sale of gas or diesel cars in Minnesota at this time, but the Walz administration could begin enacting them at any moment.
At the same time, the Walz plan for the electric grid is a page out of California's playbook, leading to skyrocketing prices and blackouts. Stay tuned for American Experiment's latest report to be released next week on the high cost of the Walz 100 percent carbon-free electricity by 2040.
Isaac Orr
Isaac Orr is a Policy Fellow at Center of the American Experiment.
Tags: ban gas cars, california, electric cars, evs, solar, wind
ACTION ALERT: Minnesota Senate will vote on the Blackout Bill tomorrow
February 1, 2023 by Isaac Orr
Sources have told me that the Minnesota Senate will be voting on Senate File 4 tomorrow, which will force electricity prices to skyrocket and cause rolling blackouts by mandating that…
Isaac Orr on The Heartland Daily Podcast: Zero-emission mandates are wholly destructive
Last week I joined my former colleague H. Sterling Burnett on The Heartland Institute's daily podcast. We chat about how zero-emission energy mandates are undermining grid reliability and substantially increasing…
Action alert! MN House of Representatives voting on the blackout bill today at 3:30 pm
The Minnesota House of Representatives will vote on the 100 percent carbon-free electricity mandate today, which means time is running out to tell your lawmaker to say NO! to this…


TAIN consortium member Diurnal announced the submission of a Paediatric Use Marketing Authorisation (PUMA) application for Infacort® to the European Medicines Agency (EMA). This application has completed the validation period and has been accepted for review by the EMA.
The TAIN consortium, was pleased to announce full results from the Phase III European study for Infacort® in paediatric Adrenal Insufficiency (AI). Positive headline data from this pivotal study were published on 11 July 2016 and today's update follows a comprehensive analysis of the data.
The Phase III trial was designed in agreement with the European Medicines Agency (EMA) and conducted in a total of 24 neonates and children under the age of six years who require replacement therapy for AI due to Congenital Adrenal Hyperplasia (CAH), primary adrenal failure or hypopituitarism.
Comprehensive analysis of the results confirms that the study met its primary endpoint, demonstrating a statistically significant (p<0.0001) increase in cortisol values following administration of Infacort® compared to pre-dose values. The median 60‑minute cortisol level achieved after Infacort® treatment was 535 nmol/L, which is comparable to the mean peak morning cortisol of healthy children.
TAIN consortium member Diurnal announced, ahead of schedule, positive headline data from the pivotal study for Infacort® in Europe for paediatric Adrenal Insufficiency (AI).
TAIN partner Diurnal announced that it has been granted Orphan Drug Designation by the US Food and Drug Administration (FDA) for Infacort®, an oral hydrocortisone formulation for the treatment of paediatric Adrenal Insufficiency ("AI"). The designation provides seven years of market exclusivity in the US after market authorisation and follows the recent Orphan Drug Designation granted by the FDA for Chronocort®, Diurnal's complementary product for adult Congenital Adrenal Hyperplasia, a related condition.
Diurnal, a member of the TAIN Consortium - a collaborative European research programme - is pleased to announce today that the first patient has been enrolled onto a Phase 3 trial of its paediatric product - Infacort® (immediate release hydrocortisone). The Infacort 003 trial is a European registration trial in paediatric patients who are less than six years of age with the rare condition Adrenal Insufficiency. The Infacort® trial is scheduled to be completed by Q3, 2016.
Adrenal Insufficiency (AI) is a condition characterised by deficiency in cortisol, an essential hormone in regulating metabolism and the response to stress. AI has been identified as an orphan disease in Europe where there are estimated to be approximately 4,000 sufferers younger than the age of six. Currently there are no licensed hydrocortisone preparations in Europe to treat these young patients with children often administered compounded adult tablets or other unlicensed products. Poor control of disease can result in precocious puberty in young children leading to virilisation and infertility, combined with fatigue and a poor quality of life in adulthood.
Infacort® represents the first-ever preparation of hydrocortisone specifically designed for use in children suffering from AI. It is a patented, immediate-release, oral, paediatric formulation of hydrocortisone that allows for release of cortisol in a manner that mimics current clinical practice. This therapeutic approach has the potential to help young patients less than six year of age suffering from diseases due to cortisol deficiency including adrenal insufficiency. AI requires life-long treatment and this novel approach to drug delivery has the potential to significantly improve these young patients' lives. The European Medicines Agency has already approved a Paediatric Investigation Plan (EMEA-001283-PIP01-12) for Infacort®, which sets out the regulatory pathway to market authorisation via the Paediatric Use Marketing Authorisation (PUMA) route.
"The start of the Infacort® study marks a significant achievement by the TAIN Consortium. We are delighted to have reached this development milestone and are very excited about the potential opportunity for this product. This Phase 3 trial has the potential to demonstrate the safety and efficacy profile of a new important therapy that could deliver patient benefits to young children living with adrenal insufficiency in Europe".
The TAIN Consortium today announced positive results from its Infacort 001 clinical study. The study in 16 healthy adult volunteers, forms part of the company's Infacort® development programme to develop a paediatric treatment for children under 6 years of age suffering from the rare disease Adrenal Insufficiency.
The trial successfully met its primary objective of demonstrating Infacort® bioequivalence to 10mg hydrocortisone tablets in healthy adult volunteers. Infacort® was shown to be safe, well-tolerated and to be of neutral taste.
Infacort® is a paediatric hydrocortisone product being developed under the European Commission funded collaborative research Framework 7 Programme ' "Treatment of Adrenal Insufficiency in Neonates (TAIN)". The programme will, for the first time, create a regulatory-approved paediatric version of hydrocortisone.
Adrenal Insufficiency is a rare disorder that prevents the body from producing sufficient amounts of the essential hormone cortisol. Hydrocortisone is a glucocorticoid hormone used as a replacement therapy for the treatment of Adrenal Insufficiency. The problem of effective hydrocortisone replacement is particularly acute among young patients (neonates and infants) for whom no licensed therapy exists. Current therapy requires adaption of adult formulations through, amongst other methods, crushing tablets. This is problematic and gives variable and inaccurate dosing as crushed tablets are relatively insoluble, provide an unpredictable pharmacokinetic profile, have no established stability, and are inconvenient for clinicians and parents. Current hydrocortisone preparations put the neonate at risk over and under treatment with potential long term health consequences including obesity, ill health and sudden death.
Infacort® is an immediate release hydrocortisone granule preparation specifically designed for use in children under 6 years of age. Infacort® is being developed under a Paediatric Investigation Plan approved by the European Medicines Agency (EMA) EMEA-001283-PIP01-12. Infacort® has been designed with taste masking excipients that are acceptable for paedriatric use and in a variety of dosage units to give maximum flexibility to clinicians to tailor the treatment to the child.
The TAIN Consortium involves European leaders in drug development, neonatology and paediatric pharmacology. The approved Paediatric Investigation Plan from the EMA will enable clinical trials to be carried out to provide sufficient evidence of safety and efficacy for Infacort® to allow submission of a Paediatric Use Medicines Authorisation (PUMA). The project also aims to raise awareness of Adrenal Insufficiency to maximise its positive impact for patients, parents and clinicians. For further information see www.tain-project.org.
"These results for Infacort® were excellent and hit all the set target success parameters. We hope to progress to Phase 3 studies rapidly. This is a very exciting time for the whole of the TAIN Consortium team."
Paediatric Investigation Plan for Infacort approved by the European Medicines Agency.
A Paediatric Investigation Plan has been approved from the European Medicines Agency (EMA) for a new formulation of hydrocortisone. Infacort® will be developed for the treatment of children under 6 years old suffering the inability to produce cortisol.
The problem of effective hydrocortisone replacement is especially acute in this paediatric setting where no licensed therapies exist. Under the Paediatric Investigation Plan, clinical trials will be carried out to provide sufficient evidence of safety and efficacy for Infacort to allow submission of a Paediatric Use Medicines Authorisation (PUMA) to the European Medicines Agency by the end of 2015 and its subsequent use in patients.
Infacort® is being developed by partners under the EU collaborative research programme - "Treatment of Adrenal Insufficiency in Neonates (TAIN)". The programme will, for the first time, create a regulatory-approved paediatric version of hydrocortisone.


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Prosecute Soldiers in Kashmir 'Encounter Killing' Repeal Armed Forces Special Powers Act
June 9, 2010 by
Press Release, HRW
(New York, June 7, 2010) – The recent killing of three men by soldiers in Jammu and Kashmir in an apparent faked encounter with so-called militants underscores the urgency for the Indian government to repeal the Armed Forces Special Powers (Jammu and Kashmir) Act (AFSPA), Human Rights Watch said today. Under the Act, which has been in force in Kashmir since 1990, soldiers may not be prosecuted in a civilian court unless sanctioned by the federal government, which is extremely rare.
Police have accused Col. D.K. Pathania and Maj. Upinder Singh of the 4th Rajput Regiment of killing three Kashmiri villagers on April 30, 2010. The military men falsely claimed that the villagers were anti-government militants and shot at the Line of Control (LOC), the effective border separating the Indian- and Pakistani-administered regions of Kashmir. The army ordered an inquiry, suspended the major, and removed the colonel from command.
"We have seen too many army inquiries, supposed suspensions, and false promises of punishment whenever soldiers are implicated in killing civilians," said Meenakshi Ganguly, senior South Asia researcher at Human Rights Watch. "But when the dust settles, the army obstructs prosecution under the Special Powers Act, and fails to deliver justice."
The army claimed that it killed three militants after it foiled their attempt to infiltrate in the Machil sector of the Line of Control, and displayed AK-47 assault rifles, ammunition, and Pakistani currency allegedly recovered from the men. Police allege, though, that a member of the Territorial Army, Abbas Hussain Shah, deliberately lured the three men – Mohamad Shafi, Shehzad Ahmed, and Riyaz Ahmed, all residents of Nadihal in Baramulla district – into army custody with an offer of jobs.
Police arrested Shah, along with two alleged accomplices, after relatives reported that the three men were missing. The police said that Shah had admitted that he took the men to a village near the border, from which soldiers transported them to the Line of Control. Shah said he was acting under orders from Major Singh. The three bodies were later exhumed and identified by their relatives in the presence of a magistrate.
"The army's narrative of shooting infiltrators is the same tired story used time and again to claim military glory," Ganguly said. "The army's special powers to operate in conflict areas are being repeatedly abused and should be withdrawn."
A government-appointed review committee recommended repealing the act in 2004 because of repeated abuse. In 2009, the Indian government promised to revise the law to ensure human rights protections, but the bill has yet to be placed before parliament. The army has resisted any curtailment of its powers under the act, particularly its immunity from prosecution, saying that it will lead to frivolous complaints and will hurt troop morale.
Human Rights Watch has documented numerous cases of faked "encounter killings."
For instance, in a 2000 case in Pathribal, the Central Bureau of Investigation filed murder charges against five army officers – Brig. Ajay Saxena, Lt. Col. Brajendra Pratap Singh, Maj. Saurabh Sinha, Maj. Amit Saxena, and Subedar Idrees Khan – for their role in abducting and killing five villagers in a staged armed encounter. The army challenged the charges under AFSPA since federal government approval had not been sought before the charges were filed. Court proceedings in the case still drag on, and none of the accused have been taken into custody or brought before a judge. According to some media accounts, some of the accused have continued to serve in the army and received promotions.
In 2007, five alleged militants killed in a joint operation in Gandherbal by the police and the army later proved to be civilians who had been abducted and murdered. Although charges were filed against the police officers involved, the army officers implicated were not handed over to the police for arrest and prosecution.
The army repeatedly claims that it prosecutes and punishes those found responsible for human rights violations in its military courts. Yet the army has never provided information to the public to support this assertion. The army has promised that the inquiry into the Machil incident will be transparent and that anyone found guilty will be punished.
"If the army is serious about punishing those responsible for this latest incident, it will transfer the suspects to the police for trial in a civilian court," Ganguly said. "Given the army's poor record in holding its soldiers accountable, there is no reason to believe that a military court can be trusted to deliver justice."
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The following section contains a brief overview of jQuery selectors.
* $("*") Selects all elements.
#id $("#foo") Selects all elements with the id="foo".
.class $(".bar") Selects all elements with the class="bar".
element $("p") Selects all <p> elements.
selector1, selector2, selectorN $("h1, p.bar, span") Selects all <h1> and <span>, but only that <p> elements that has the class="bar".
:first $("p:first") Selects the first <p> element.
:last $("p:last") Selects the last <p> element.
:even $("tr:even") Selects all even <tr> elements, zero-indexed.
:odd $("tr:odd") Selects all odd <tr> elements, zero-indexed.
:eq() $("tr:eq(1)") Select the 2nd <tr> element within the matched set, zero-based index.
:not() $("p:not(:empty)") Select all <p> elements that are not empty.
:lt() $("ul li:lt(3)") Select all <li> elements at an index less than three within the matched set (i.e. selects 1st, 2nd, 3rd list elements), zero-based index.
:gt() $("ul li:gt(3)") Select all <li> elements at an index greater than three within the matched set (i.e. selects 4th, 5th, ... list elements), zero-based index.
:header $(":header") Selects all elements that are headers, like <h1>, <h2>, <h3> and so on.
:lang() $(":lang(en)") Selects all elements that have a language value "en" i.e. lang="en", lang="en-us" etc.
:root $(":root") Selects the document's root element which is always <html> element in a HTML document.
:animated $(":animated") Select all elements that are animating at the time the selector is run.
:first-child $("p:first-child") Selects all <p> elements that are the first child of their parent.
:last-child $("p:last-child") Selects all <p> elements that are the last child of their parent.
:nth-child(n) $("p:nth-child(3)") Selects all <p> elements that are the 3rd child of their parent.
:only-child $("p:only-child") Selects all <p> elements that are the only child of their parent.
:first-of-type $("p:first-of-type") Selects all <p> elements that are the first <p> element of their parent.
:last-of-type $("p:last-of-type") Selects all <p> elements that are the last <p> element of their parent.
:only-of-type $("p:only-of-type") Selects all <p> elements that have no siblings with the same element name.
:nth-last-child(n) $("p:nth-last-child(3)") Selects all <p> elements that are the 3rd-child of their parent, counting from the last element to the first.
:nth-last-of-type(n) $("p:nth-last-of-type(2)") Selects all <p> elements that are the 2nd-child of their parent, counting from the last element to the first.
:contains() $('p:contains("Hello")') Selects all <p> elements that contains the text "Hello".
:empty $("td:empty") Selects all <td> elements that are empty i.e that have no children including text.
:has() $("p:has(img)") Selects all <p> elements which contain at least one <img> element.
:parent $(":parent") Select all elements that have at least one child node either an element or text.
:input $(":input") Selects all input, textarea, select and button elements (basically selects all form controls).
:text $(":text") Selects all input elements with type="text".
:password $(":password") Selects all input elements with type="password".
:radio $(":radio") Selects all input elements with type="radio".
:checkbox $(":checkbox") Selects all input elements with type="checkbox".
:button $(":button") Selects all input and button elements with type="button".
:submit $(":submit") Selects all input and button elements with type="submit".
:reset $(":reset") Selects all input and button elements with type="reset".
:image $(":image") Selects all input elements with type="image".
:file $(":file") Selects all input elements with type="file".
:enabled $(":enabled") Selects all elements that are enabled.
:disabled $(":disabled") Selects all elements that are disabled.
:selected $(":selected") Selects all elements that are selected, only works for <option> elements.
:checked $(":checked") Selects all elements that are checked or selected, works for checkboxes, radio buttons, and select elements.
:focus $(":focus") Selects element if it is currently focused.
[attribute] $("[href]") Selects all elements with a href attribute, with any value.
[attribute="value"] $('a[target="_blank"]') Selects all <a> elements that have the target attribute with a value equal to "_blank".
[attribute="value"] $('a[target!="_blank"]') Selects all <a> elements that don't have the target attribute, or if have don't with a value "_blank".
[attribute$="value"] $('img[src$=".png"]') Selects all <img> elements that have the src attribute with a value ending with ".png".
[attribute|="value"] $('a[hreflang|="en"]') Selects all <a> elements that have the hreflang attribute with a value equal to "en", or starting with "en" followed by a hyphen, like "en-US".
[attribute^="value"] $('img[title^="Smiley"]') Selects all <img> elements that have the title attribute with a value beginning exactly with a "Smiley" string.
[attribute~="value"] $('img[title~="Kites"]') Selects all <img> elements that have the title attribute with a value containing the word "Kites", delimited by spaces.
[attribute*="value"] $('input[name*="male"]') Selects all <input> elements that have the name attribute with a value containing the substring "male".
parent > child $("ul > li") Selects all <li> elements that are direct child of their parent <ul> element.
ancestor descendant $("form label") Selects all <label> elements that are descendant of their ancestor <form> element.
prev + next $("h1 + p") Selects all <p> elements that are next i.e. immediately preceded to the <h1> elements.
prev ~ siblings $("h1 ~ p") Selects all <p> elements that are siblings and follow after the <h1> elements.
:hidden $("p:hidden") Selects all <p> elements that are hidden.
:visible $("p:visible") Selects all <p> elements that are visible.
[attribute!="value"] $('a[target!="_blank"]') Selects all <a> elements that don't have the target attribute, or if have don't with a value "_blank".


The bag features a large interior zip pocket as well as two smaller pockets and a large zip pocket to close the tote. It also features a large CC sign on the front of the bag. Great for casual yet chic wear.


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"Economists are puzzle solvers..."
An interview with Robert Merton
Career-Awards
Two days after his Nobel Prize was announced, Professor Merton spoke with Bulletin editor Deborah Blagg in his Morgan Hall office, where imposing stacks of scholarly journals had been displaced temporarily by a garland of colorful balloons and numerous congratulatory floral bouquets.
Bulletin: What were you doing when you heard the news?
Merton: I was just about ready to leave for an early morning flight to New York. The phone rang in my apartment at about quarter to six. I could easily have been out the door. I answered the phone, and the secretary general of the Royal Swedish Academy introduced himself and said, "I have some interesting news for you."
Bulletin: Were you surprised?
Merton: I certainly was surprised, overwhelmed, and very happy. There are many people who have done remarkable work in this field. I am truly honored to have been chosen.
Bulletin: You have said that your father [Robert K. Merton, a National Medal of Science winner whose work in theoretical sociology at Columbia University has spanned fifty years] has been a strong influence in your life and your career. What did he say when you told him?
Merton: My father is the really serious academic in the family. He created the sociology of science; terms such as focus group, role model, and self-fulfilling prophecy are all familiar to us because of his work. He's 87 now, a university professor emeritus at Columbia, and a scholar at the Russell Sage Foundation. And we're very close; we've talked to each other every day for the last thirty years.
Anyway, when I called him in New York, he just was beside himself. When he later learned there would be a reception for me at HBS that day, he wanted to get to Boston as quickly as possible. He couldn't find a taxi to the airport outside his apartment, so he raced up a steep hill to Broadway, found a cab, and for the first time in his life he gave a driver a couple of extra bills with instructions to get him on the next shuttle at LaGuardia. He said his son had just won a Nobel Prize, and the cab driver made him spell the name Merton so that he'd have it right when he told the story.
Bulletin: Will your father be going to Stockholm with you when you accept the prize?
Merton: Yes, he'll be with me in December.
Bulletin: You mentioned how some of the concepts your father introduced have found their way into everyday vernacular. Are there applications of your own work that would be familiar to the average noneconomist?
Merton: In 1973, when the late Fischer Black, Myron Scholes, and I published the research recognized by this prize, option pricing was considered a fairly esoteric area. Myron and Fischer were working on a formula for option valuation. I looked at what they were doing and came up with an alternative - some say more robust - way to derive the formula that has since turned out to have very wide applicability. But at the time, the work only had direct implications for pricing over-the-counter options and some executive stock options.
The methodology we developed to solve that original problem, however, gave us an insight into solving a wide range of other problems. I think of the process of discerning other applications as a little bit like peeling an onion: once we gained the initial understanding, we began to see a whole world of possibilities open up. An option is a fundamental security now - whether linked to interest rates, stock indexes, currencies, commodities, or real estate. But that's only part of it. There are other financial things that have the same structure as an option and can thus be analyzed in the same way.
A home mortgage is a simple example of how our work is commonly applied. Most mortgages allow the homeowner the option to prepay the mortgage before its term is up. That option to prepay has a value, and banks need to know how much to charge for it up front. In order to determine that, they really need to be able to analyze what the chances are that the mortgage will be prepaid - in other words, what the risk is to them. What our analysis did, in addition to improving the means to price options, was to provide a way to measure risk exposure.
Bulletin: Why has the methodology been so widely used?
Merton: One answer is, simply, that it filled a need. It wasn't intellectual interest that made people want to apply it. In the 1970s, profit margins to options dealers were driven down, competition was going up, and options investors no longer could operate based on simple heuristics and guesswork. This theory enabled options transactors to take much bigger positions because they were hedged; they could be much more efficient, and they could control their risk much better.
If you look at the last 25 years of extraordinary financial innovation and institutional change - with structural changes in financial systems all over the world - it's easy to see why the ability to take financial securities and products, many of which never existed before, and analyze them both with respect to pricing and risk characteristics turned out to be a very powerful tool.
Bulletin: How do you present this theory to your students?
Merton: What the formula captures permeates many financial aspects of life. One way I present it in the classroom is to have the students design a security. We call it a squiggle. They ask, "What's a squiggle?" I say, "I don't know yet. You're going to design it for me." And in real time, they design the payoffs to the security.
Then I say, "Now, I'm going to show you how we price and analyze the risk of this just-created security." I take them through and apply the analysis, and boom - within a class session, we've worked out how this thing has to be priced. So they see that even with an instrument that never existed before they came into the classroom that day, the theory allows us to price it and measure its risk.
Bulletin: When did you first become interested in the field of economics?
Merton: I bought my first share of stock in General Motors (I've always been a car buff!) when I was ten. I can remember going with my dad to the stockbroker's and sitting there watching the NYSE and AMEX tapes, learning all the companies' symbols. And when I was in graduate school in applied mathematics at Cal Tech, I'd get up and go to the broker's at 6:30 (9:30 EST) to trade over-the-counter options and convertible bonds until I had to go to class at 9:00.
But it wasn't until I was contemplating the topic of my Ph.D. thesis that I started thinking about switching from applied math to economics. I had always been interested in financial markets, and I found myself thinking that unlike a career in applied math, where most of the work is pretty esoteric, if I could really make a breakthrough in economics, I might affect an awful lot of people.
So, much to the chagrin of both my family and my advisors at Cal Tech, I applied to a bunch of economics departments. Since I only had one undergraduate economics course on my transcript, all but one school turned me down.
Bulletin: MIT offered you a full fellowship?
Merton: Yes, and MIT had Paul Samuelson. My first semester there I took his course on mathematical economics and loved it. A paper I wrote for the course was later published, and Paul asked me to become his research assistant.
Working with him was critical to me, because he was one of the few economists at the time whose work really integrated sophisticated mathematics and financial economics. That real-world application of complex theory was very attractive to me, and when I realized that financial market problems could be a legitimate area for serious academic research, I was off and running.
One of the nice things about this award of the Nobel is that it further underscores the legitimacy of finance as a mainline field in economics. I get such a kick out of being able to bridge the highly mathematical world of formulas and the hands-on world of the markets.
Bulletin: Can you describe what it's like to work at this level of intellectual sophistication?
Merton: Economists are puzzle solvers, and some solve purely empirical puzzles, where you work long hours evaluating data one step at a time, trying every permutation, and after years of this, you hope to find something. That can be really fascinating and rewarding.
The research that I like best, however, typically starts out as theoretical and not empirical, but I always try to bring my financial common sense to bear on it. The art of theoretical model-building is to make good abstractions that also capture the essence of the world that you're trying to explain. That's the fun. That's the challenge. I've been doing this for close to thirty years, and I'm always excited when it really works. To have both intrinsic intellectual challenge and excitement and extrinsic application - it just doesn't get any better than that.
Bulletin: At 53, you are the second youngest economist ever to win a Nobel Prize. Where do you go from here?
Merton: In terms of research, for several years I have been working with colleagues in the HBS finance group on something called the Global Financial System Project. We are trying to understand the global financial system and the implications of institutional change.
Our conceptual framework to date is that because the institutions themselves are changing so dramatically - just look, for example, at the transformation of banks and insurance companies in the last couple of decades - we can't expect them to be our analytical anchors. Instead, we've decided to analyze the global financial system by looking at universal financial functions.
Bulletin: We spoke earlier of sophistication; this sounds like research based on very basic principles.
Merton: In a way, yes. All of us, whether we live now or a hundred years from now, in New York City or in Bali, are served by various financial functions as we go through life. We are born, we need to acquire shelter, we work, we borrow or lend money, we sell things, we retire, etc. Our group takes these functions as our unit of analysis and asks, "At any given time and place, with technology, geopolitical change, and a host of other variables factored in, what's the best way to structure an institution that performs those functions?"
The spirit of it is to try to devise a way of thinking about institutional change in an organized way in the global financial system. We're still at an early stage in this, but I'm finding it very exciting.
Bulletin: So you'll still have plenty to keep you busy when you come back from Sweden.
Merton: I have no thoughts of early retirement!
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Peak to Peak: Ephesians 3:20-21 | Study the Bible with me!
Ephesians 3:20-21 is Paul's declaration of praise to God for what He has done and what He is able to do. These two verses in Ephesians bring the first 3 chapters to a grand doxological finale, but rather than making it the last thought before changing subject, they create a transition and bridge to the next 3 chapters.
This statement of faith and praise is not only related to what Paul has already described in Ephesians 1 -3 but it is also related to what he is about to describe in Ephesians 4 – 6. The first half of Ephesians is about what God has done, and what we are to believe. The second half of Ephesians is about what we are to do and how we are to behave. These verses show us that GOD IS ABLE to work within us so that we will walk according to His ways.
It is truly exciting and I think that the Peak 2 Peak Alpine Gondola in the Whistler-Blackcomb Mountains provides an excellent illustration of what these verses make possible!
The PEAK 2 PEAK Alpine Experience is about opening up Whistler Blackcomb's incredible potential for adventure. From an alpine meal to pleasant strolls to epic hikes, the possibilities are infinite.
for an incredible potential for adventure!
… abundant life in Christ… the possibilities are infinite!
This entry was posted in Bible, Ephesians, Immeasurably More and tagged ability, Ephesians, glory, Immeasurably More, power, praise. Bookmark the permalink.