Adult Sinsations guarantees same day picking, packing and processing of all orders placed before 5pm (WST) Monday to Sunday, seven days a week, 52 weeks a year (including public holidays but excluding the Christmas period). All orders received after 5pm (WST) will of course, be picked, packed and processed the very next day – rain, hail or shine!
Free Delivery for all orders of $200 or more (excluding delivery charges and after any discounts have been applied or promotional products have been added to your shopping cart). Your pleasure parcel will be sent to you using Australia Post's Standard Parcel Service (see delivery times below). If you wish to receive your pleasure parcel via Australia Post's Express Parcel Service though, a delivery charge of $14.95 will apply (again see delivery times below).
$9.95 Standard Parcel Post for all orders under $200 using Australia Post's Standard Parcel Service, which covers most of Australia. Australia Post undertakes to deliver your pleasure parcel within two (2) business days to addresses within the Perth metropolitan area and within 3 – 4 business days to addresses within country Western Australia. Delivery to other capital cities can take between 5 – 6 business days, while delivery to other interstate locations, including remote areas and roadside addresses, may take a little longer.
$14.95 Express Parcel Post for all orders under $200 using Australia Post's Express Parcel Service, which provides next business day delivery to addresses within Australia Post's Express Post delivery network. This network covers 80% of Australian business addresses, private addresses and post office boxes, however if your pleasure parcel is to be posted to an address outside this network, while Australia Post undertakes to use the fastest transport links possible, it cannot guarantee next business day delivery.
You may of course elect to collect your pleasure parcel in person from one of our retail stores. When placing an order for In-Store Parcel Pick Up using our website, you simply need to nominate the store location you wish to pick your pleasure parcel up from and then complete the checkout process. An in-store pleasure professional from your nominated store will contact you via telephone when your order is ready for collection. There is no fee for this service; however you must remember to bring along your Tax Invoice as proof of purchase.
Please note that Australia Post deliveries are made Monday to Friday only, excluding public holidays. Australia Post does not currently offer a weekend delivery service and they have advised that deliveries may take longer than their usual timeframes during peak shopping periods, such as Christmas. Delivery during the "wet season" (our favourite time of year) into the Northern Territory and Northern Queensland may also be affected by adverse weather conditions.
Some delivery services now include online tracking of your pleasure parcel so you can keep an eye on the prize during the delivery process! Simply visit Australia Post's online tracking tool, enter the unique Item Tracking Number which appears on your Order Summary and discover real-time delivery information, including when your pleasure parcel is lodged with Australia Post, when your pleasure parcel is in transit and/or on board with an Australia Post driver, and when your pleasure parcel is delivered to your front door (the happiest time of all)! You can also choose to use Australia Post's free Track Advice and receive email notifications regarding the journey of your pleasure parcel. Visit the Australia Post website at http://auspost.com.au/parcels-mail/our-tracking-service.html for more information.


Welcome to Dakota Storage Products. Our mission is to provide top quality warehouse and material handling products at competitive prices coupled with expert knowledge and friendly service. Our goal is 100% customer satisfaction!
From pallet rack, storage rack, cantilever rack and other warehouse racking systems to safety ladders, lift tables, pallet jacks and material handling products of all kinds Dakota Storage Products can provide nearly everything for your warehouse. We also handle all the equipment and accessories for your loading dock. If your warehouse needs it, we can supply it! Please stop by and visit us-easy access from both I-94 and I-29! We are located just one mile east of the Red River Valley Fairgrounds in the Westgo Square Building.
You can trust us to be consistent and trustworthy when you work with Dakota Storage Products. Since we are family owned, we take pride in our work. Expect us to give you our full attention all the way through the process of planning, ordering, and installing your pallet racking and storage equipment.
We supply pallet racking and storage equipment for many industries including manufacturing, farms, warehouses, food suppliers, and retail stores.
Dakota Storage Products' story began in 1989 when Merlyn Nelson opened the business in Westgo Square in West Fargo to help meet the needs of companies and small businesses throughout the region.
Merlyn retired in 2008, and his daughter Kari took over the operations with the help of her family.


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Law and Daily Life
Is It Legal to Let a Kindergartner Walk Home From School?
By Lisa M. Schaffer, Esq. on September 05, 2018 7:03 AM
In a Northern California city last week, five year-old Kirby Jackson walked home from school after he ended his kindergarten day. He walked home, alone, around noontime, through three miles of busy streets. No one noticed. Once home, he called his mom at work to say hi, which almost gave his mother a heart attack. He was supposed to be in after-care at his local public elementary school. When the mother called the school to see what had happened, the school didn't even know Kirby was gone.
Can a School Release a Kindergartner to No One?
Absent any state or local laws to the contrary, a school can release a kindergartner from school without a parental hand-off. Passed in 2016, the Every Student Succeeds Act is a federal rule that protects the rights of kids (let's be honest - it protects the right of "free range parents") to walk or go out alone. The act was intended to provide protection to parents who feel that their kids should be allowed some autonomy to get by on their own. However, it can be overridden by state and local municipalities, who are deemed to know the safety of their local streets best.
So It's OK to Let My Kindergartner Walk Home Alone?
State laws are intentionally vague on this issue, leaving it up to the parent's discretion. But beware parents -- Child Protective Services can be called on you if your judgment is unreasonable by local standards. If parents are looking for some accepted guidelines, the Safe Routes to School program recommends children under the age of 10 not cross a street alone.They believe that the best criteria for making this judgment call is to evaluate the distance to the school, the availability of sidewalks, the type of neighborhood and the local street safety measures. The consensus seems to be that 5-year-olds are too young, 6- and 7-year-olds should walk in a group and that by age 10 most kids are ready.
Can Kirby's Parents Sue the School?
Do Kirby's parents have a claim for negligence in this situation? The five elements of a negligence case are: duty, breach, actual and proximate causation, and damages. There was clearly a duty of care: his parents had signed him up for after-school care, and it was the duty of the school to supervise Kirby during the after-care session. Letting him slip out of their hands was certainly a breach of that care. However, Kirby did make it home safely, and frankly, he was very proud of that accomplishment. His parents didn't learn about the walk until after he arrived home, and so it's hard to show duress. In order to have a negligence claim, there has to be some injury or damage that can be made whole through a monetary payment.
Time will tell if there were any injuries from this duty and breach that weren't immediately apparent. To date, the school district has been very tight-lipped about the situation. Kirby's parents are justifiably angry that the school isn't saying more than "no harm, no foul" here.
If you or your loved ones have been the victim of a negligence claim, either by a school or someone else, call a local personal injury attorney, who can listen to your unique situation, and provide you with some guidance and suggestions for next steps.
Find a Local Personal Injury Attorney (FindLaw Lawyer's Directory)
Common Reasons Teachers Get Sued (FindLaw Law and Daily Life Blog)
5 Common Homeschooling Legal Questions (FindLaw Law and Daily Life Blog)

redpajama_set_name: RedPajamaCommonCrawl


text:
AirlineHub
Best Airlines in the World and all about Aviation
WTTC: One Million Jobs a Day Being Lost Due to Coronavirus Pandemic
March 21, 2020 france
London (United Kingdom) – A staggering one million jobs are being lost every day in the Travel & Tourism sector due to the sweeping effect of the coronavirus pandemic, according to the World Travel & Tourism Council (WTTC). According to the London-based international organisation, which represents the global Travel & Tourism private sector, the growing job losses are affecting every level of the industry and are gathering pace, as countries go into lockdown to tackle the virus.
WTTC says the vast closure of hotels, suspension of the majority of international and domestic airline flights, cessation of cruise lines and growing global travel bans are having a catastrophic 'domino effect' hitting huge numbers of suppliers worldwide.
Small and medium sized businesses at every level within Travel & Tourism, such as tour operators, travel agents and sole-traders, are especially vulnerable.
The organisation, which is already in talks with over 75 governments around the world, has called for countries to urgently do more to intervene to make clearer how businesses can access potentially life-saving loans, and tax breaks, to prevent them from imminent collapse.
WTTC is mindful that while the Travel & Tourism sector is facing an economic meltdown the coronavirus pandemic is primarily a global health disaster, which governments are doing all they can to contain the spread and reduce the number of deaths.
Gloria Guevara, WTTC President & CEO, said: "While the priority for governments is to keep people safe, this global health catastrophe means a million people a day in the Travel & Tourism industry alone are losing their jobs and facing potential ruin due to the disastrous impact of the coronavirus pandemic.
"It is heartbreaking that the livelihoods of millions of people who have dedicated their lives to the Travel & Tourism sector are being decimated; from waiters to taxi drivers, guides to chefs and caterers, pilots to cleaners.
"The relentless cascade of job losses is plunging millions of families into terrible hardship and debt, fearful of how to buy food and pay their bills. The domino effect of Covid-19 is right now having a massive impact, wiping out an entire economic sector.
"Businesses large and small are being forced to rip up their three-year plans and focus on a three-month fight for survival on a daily basis, while people's jobs are wiped out hour by hour. We fear this situation will only deteriorate unless more action is taken immediately by governments to address it.
"While some governments have been quick to respond with promises of help, the majority of businesses still have no idea how to access these potentially life-saving loans and tax breaks.
"Today we call on governments around the world to make crystal clear how businesses can access funds, which can prevent the hemorrhage of jobs throughout the Travel & Tourism sector."
The plea for urgent action came following an analysis by WTTC of its members, which represents every level of the Travel & Tourism sector. Up to 50 million jobs throughout the world are at immediate risk, with up to 320 million jobs facing the impact of the dramatic loss of business.
According to WTTC's latest research Travel & Tourism contributes to 10.4% of Global GDP, is directly responsible for generating one in 10 of the world's jobs and, for eight successive years, has outpaced the growth of the global economy.
Earlier this week, WTTC announced a three-point plan for governments to take to combat the devastating effect of Covid-19.
This comprised:
1. Protect the salaries, incomes and jobs of the millions of people who are at risk
2. Extend vital, unlimited interest-free loans to provide liquidity to large and small Travel & Tourism businesses to prevent them from collapse
3. Waive or remove all dues, taxes or fiscal charges for 12 months that affect cash flow which can be critical to businesses survival.
← Thailand Property Awards to be Held in November 2020
UNWTO Convenes Global Tourism Crisis Committee →
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▪ Alekseev, V.I., Marin, Yu.B., Gembitskaya, I.M. (2018): Gahnite in Rare-Metal Metasomatic Rocks of the Verkhneurmiysky Ore Cluster, Amur River Region. Geology of Ore Deposits, 59, 765-770.
A new finding of Zn-spinel (gahnite) in biotite metasomatic rock of the Verkhneurmiysky copper–tungsten–tin ore cluster is described in this paper, including the chemical composition of gahnite, its paragenesis, and place in the regional evolution history of hydrothermal processes. Gahnite is commonly localized in biotite–microcline metasomatic rocks at the lower subore stage of the greisen metasomatic column in proximity to the exocontact of the rare-metal granite massif. Gahnite from rare-metal ore occurrences belongs to the hercynite–gahnite–franklinite isomorphic series and contains significant isomorphic admixtures of iron (24.3%) and manganese (0.65%). Based on our results and earlier published data, it is suggested that gahnite can be a mineral-indicator of rare-metal metasomatism.


A Lodge of Sorrow is a ritual intended to celebrate the memory of our departed brethren. The Lodge remains open for the term of one year.
Corinthian Lodge mourns the loss of Brother Don Lee Latimer. Brother Latimer moved on to the celestial lodge above on November 13th, 2013. He was a lifetime Master Mason of over 60 years.
Corinthian Lodge mourns the loss of Worshipful Brother Gerald Grover Grant. Worshipful Brother Grant moved on to the celestial lodge above on December 1st, 2013.


MCIM Module I will prepare students who are the first responders to a mass casualty incident to take appropriate initial control actions of the medical problem and perform the initial triage of patients.
MCIM Module II provides more in depth information on managing mass casualties, including creating the medical command structure. A table top exercise helps practice the skills taught in the class.


text:
Житни Поток је насељено место града Прокупља у Топличком округу. Према попису из 2002. било је 592 становника (према попису из 1991. било је 663 становника)

До 1965. ово насеље је било седиште Општине Житни Поток коју су чинила насељена места: Арбанашка, Богујевац (тада под званичним именом Богојевац), Бреговина, Бублица, Доњи Статовац, Драги Део, Гласовик, Горњи Статовац, Јабучево, Кожинце, Крушевица, Мачина, Мрљак, Нови Ђуровац (тада под званичним називом Нови Ђуревац), Обртинце, Пестиш, Ранкова Река, Ргаје, Средњи Статовац, Стари Ђуровац (тада под званичним називом Стари Ђуревац), Старо Село, Шевиш, Широке Њиве, Товрљане, Трнови Лаз, Власово, Злата и Житни Поток. После укидања општине подручје бивше општине је у целини ушло у састав општине Прокупље.

Прошлост
Село је добило име по "житу"; велика поља жита су га одувек окруживала. Ту су расла најбоља жита Нове Србије. Налазило се у 19. веку у једној питомој удолини, коју пресеца водоток Житни поток.

Житни Поток је настао 1878. године од досељеника Шопова из Црне Траве. До српско-турског рата то је било "највеће и најлепше" арнаутско село. Све куће су биле бело окречене, покривене ћерамидом, што иначе није било правило (већ једини случај) код Арнаута. Током рата село је попаљено; остале су читаве две-три куће. Припао је цео тај крај звани Пуста Река кнежевини Србији. У административном погледу 1879. године Житни Поток је припао округу Топличком а срезу Јабланичком. У селу је у то време 52 куће, са 373 душе - све Срби. Држава је убирала приходе ог пописаних 77 пореских глава.

По опису из 1882. године место је најлепше село и сред-среда општине Житнопоточке. У склопу те општине је чак девет села са 228 кућа - искључиво насељеничких. Општински атар пресецају водотоци Пуста река и Злата. Терен није раван, плодност земљишта је неуједначена. и покривен је шумом, које има у изобиљу.

У Житном Потоку је од осамдесетих година 19. века радила српска основна школа. Године 1879. ту није било писмених људи, јер је школа отворена касније. Била је по извештају из 1896. године четвороразредна са укупно 98 ђака. У месту које припада Топличком округу, добричком срезу, тада је учитељ Лазар Миљковић.

У Житном Потоку као општини било је 1901. године поред Житног Потока још осам села. Уз село Житни Поток била су "селца" Ђуровац и Мачина.

Током Првог светског рата у Житном Потоку је прво била једна мања бугарска јединица са два официра. Када је она повучена на фронт, дошла је нова бугарска војска, са старијим кадром, а нови командант је био подпоручник Гаврило Прзанов. Пошто је Прзанов је био "Русофил" а толерантан, народ није више толико страдао; било је мање убијених и интернираних. Када је дошао у околину четнички војвода Коста Пећанац, Прзанов није ништа предузео. Отишли су из села тада у четнике, Михајло Стојичић општински писар и Драгољуб Константиновић. За време Топличког устанка почетком 1917. године Бугари су држали положај у Житном Потоку. Командант места био је бугарски поручник Прзанов, а ту је стигла као појачање бугарска артиљерија. Месни пешадијски гарнизон је оставио простор за артиљерију, и упутио се у сусрет српским четницима у Куршумлији. Мајор бугарске војске Попов је водио борбе против Срба око Житног Потока. Крајем Првог светског рата, 26. септембра 1918. године место Житни Поток је заузела - ослободила српска коњица. Била је коњица у саставу Прве српске армије.У месту је било немачке војске, а официра и неколико војника су том приликом Срби заробили.

Пре и после 1927. године у Житном Потоку су одржавана четири годишња, вишедневна вашара. Мењали су се само термини одржавања. Марта 1927. године основан је у месту спортски фудбалски клуб "Устанак". Клуб је имао тада 75 чланова, а поред фудбала ови су били активни и у позоришној, певачкој и трезвењачкој секцији. Клуб је имао седиште у једној посебној згради и снадбевен свим потрепштинама. Годину дана је требало да се клуб оснује и започне рад, а истакли су се у том послу шесторица учитеља, председник општине Радослав Ђокић, обласни посланик Величко Ђорђевић и више месних трговаца и млађих мештана.

Пред Други светски рат за Житни Поток се каже да је то "чувено и напредно село". Вредни мештани су до тада подигли цркву, школу, општинску кућу, пошту и "Жито Поточку амбуланту". Први општински лекар је треба да дође у лето 1940. године. Међутим ни до средине септембра 1940. године др Стојановић се није појавио, мада је треба да долази сваког четвртка, у амбуланту у главној улици.

Неколико породица из Житног Потока се 1947. године колонизовало у насеље Српски Милетић у Бачкој. Зидар Стојанче Ивановић (из Житног Потока) је био један од градитеља зграде Скупштине Краљевине Југославије у Београду.

У месту је између два светска рата учитељица била Миља Ивановић. Венчали су се 1935. године, на основу војног решења датог 21. августа. Пешадијски поручник Божидар Ивановић, узео је за супругу учитељицу Миљу, кћерку почившег економа, Божидара Динића из Житног потока. Божо Ивановић, предратни капетан погинуо је 1944. године, код мајор Југословенске краљевске војске у отаџбини. Њихов син је, познати "српски књижевник Иван Ивановић, аутор романа "Црвени краљ". Иван је због својих дела био у послератној Југославији, "забрањен и прећутан писац"; вољом комуниста остао је изван књижевног живота.

Отворена је након Другог светског рата прогимназија у Житном Потоку.

Демографија
У насељу Житни Поток живи 446 пунолетних становника, а просечна старост становништва износи 40,8 година (38,6 код мушкараца и 43,0 код жена). У насељу има 225 домаћинстава, а просечан број чланова по домаћинству је 2,63.

Становништво у овом насељу веома је нехомогено, а у последња три пописа, примећен је пад у броју становника.

Референце

Спољашње везе

 Мапе, аеродроми и временска ситуација локација (-{Fallingrain}-)
 Сателитска мапа (-{Wikimapia}-)
 Гугл сателитска мапа (-{Maplandia}-)
 План насеља на мапи (-{Mapquest}-)

Град Прокупље
Насељена места у Топличком управном округу
Википројект географија/Насеља у Србији

redpajama_set_name: RedPajamaWikipedia


Friday, February 8, 6:30 p.m. to 11:30 p.m.
Saturday, February 9, 6:30 p.m. to 11:30 p.m.
La Nouvelle Scéne, Studio A and Studio B, 333 King Edward Ave, Ottawa.
From New York to Vancouver and Montreal to Halifax, a bevvy of significant festival favourites are heading to Ottawa to participate in this year's Festival. Ardent music lovers will have the opportunity to hear famed headliners pianist Joey Calderazzo and vocalist/pianist/ukuleleist Nellie McKay along with a consummate collection of artists. The 33z are back with a special tribute to the Queen of Soul, Aretha Franklin. Visit ottawajazzfestival.com/shows for the full lineup and tickets.
Presented by the Ottawa Jazz Festival in partnership with TD Bank.


Future Network Marketing, mlm for the 21st century and beyond.
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Going to compose a comparative paper in the nearest time? If yes, you'd Writing Tips For Students: Words To Use In A Comparative Essay In like manner – This is another great phrase to use in a comparative essay and works.
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Home Music DJ Shadow, Cut Chemist spin an infectious night of historic vinyl
updated on March 14, 2018 November 18, 2014 Music
DJ Shadow, Cut Chemist spin an infectious night of historic vinyl
EDUARDO MORALES Leave a Comment on DJ Shadow, Cut Chemist spin an infectious night of historic vinyl
"This record," Cut Chemist said, raising up a hallowed selection of 12-inch vinyl, "is the one that sits next to the Gettysburg Address." He then gently set the disc on the turntable, where it became a preeminent part of his score, to the delight of the dancing crowd.
Make no mistake, there is deep history in vinyl grooves.
The record, the acid demo vinyl of Afrika Bambaataa's "Looking for the Perfect Beat," anchored Monday night's show at the Georgia Theatre, where Cut Chemist (Lucas MacFadden) and DJ Shadow (Josh Davis) spun two hours of records from the collection of the hip-hop godfather. Bambaataa's collection (which sits at Cornell University "in the same vault as papyrus scrolls – no seriously we were there – and the Gettysburg Address," said Shadow) was the night's star with the two DJs ensuring it got the proper treatment.
Shadow and Cut Chemist, master DJs in their own right with decades of experience, have embarked on a Renegades of Rhythm tour to share the sounds which influenced them to become turntablists. Taking the audience on an audio and visual tour of hip-hop culture, the pair spun through songs of endless variation – from Sugar Hill Gang's "Rapper's Delight," Kraftwerk's "Trans Europe Express," "The Message" by Grandmaster Flash and The Furious Five, and Yes' "Owner of a Lonely Heart."
Yes, I said Yes.
It was Shadow's second time in Athens (Cut Chemist's first) but he told the crowd they'd see something they've never seen before. And with that, he dropped a James Brown record and the night was off. Flanked by a large video screen showing images of Bambaataa's vinyl collection, gritty and graffitied New York streets and spray-paint collages, the two took turns deftly moving through a timeline of musical genres.
There was the funk and soul of James Brown and Sly and the Family Stone, moving to the salsa of Willie Colon and on to disco "but not the disco you're used to hearing," Cut Chemist added. "Good Times," the monster hit from Chic (which is also known as the backing music for "Rapper's Delight") opened the rap portion of the show. There was not a still person in the place.
Throughout the two displayed their stellar skills with the wax, using their six turntables to play off one another, finish each other's musical sentences, flip from reggae to go-go to disco in an instant, or at one point, synchronize scratch without missing a beat. Cut Chemist brought out a 1967 drum machine, the one Grandmaster Flash used in 1980, to create his own beats while Shadow bashed on another vintage drum machine across the way. And despite playing instruments and music more than 35 years old, it all felt modern and timeless.
The night found some reggae and dub, moved to go-go (Bambaataa insisted on it, Shadow noted), and included a full series of songs from Bambaataa and his band the Soulsonic Force. The highlight, the weird and infectious "Planet Rock" with its B-side "Looking for the Perfect Beat," infused all elements of the night to this point. Bambaataa's record collection would become his music, which in turn would shine a light on back on the collection itself.
There were no better ambassadors than DJ Shadow and Cut Chemist. When superstars of a craft share what made them that way, it's best to listen.
And on this night, dance along.
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La sinfonietta para orquesta en re major va ser composta per Ernesto Halffter el 1925 i es pot considerar una de les primeres obres de l'estil neoclàssic dins del panorama espanyol, coincidint en el temps amb la belle époque.

La composició de la simfonietta hagués tingut, possiblement, un altre caire si no hagués passat repetides vegades per les correccions del seu únic mestre: Manuel de Falla. Amb aquesta obra, Halftter va guanyar el Premi Nacional de música d'Espanya (1925).

Ernesto Halffter emmarcava la seva obra en un ambient cortesà i a la vegada popular i jocós del  a Espanya.

Estil i història
Al 1925 l'estil neoclàssic estava en plena expansió a Paris; així com particularment dins de la continua evolució de compositors com Falla, i per empatia de la d'Ernesto Halffter. El títol de "sinfonietta" podria haver estat substituït pel de "simfonia", ja que la forma global i l'estructura interna de quatre moviments apareix igualment tant en una forma com en l'altra. No obstant, sembla que Halffter volia evidenciar els diferents caràcters d'aquell  des del propi títol de la seva obra, cosa que potser no hagués aconseguit amb el títol de "Simfonia", associat per una banda al Classicisme, també per l'altra al Romanticisme.

Tot i saber les prioritats que tenien els dos germans Halffter i Falla per Domenico Scarlatti, l'estil resultant de les evocacions que es fan a la Sinfonietta per a orquestra és més directe i proper al Pare Antoni Soler (1729-1783), i d'aquesta manera més als preclàssics que als barrocs tardans.

Pels girs melòdics i les formes, l'autor de l'obra intentava imitar aquells compositors espanyols de la segona meitat del . De fet, Antoni Soler, prototip del músic pre-clàssic a Catalunya, va mantenir pràcticament vigent unes dècades més la música del seu professor Domenico Scarlatti, deixant-se influenciar per aquest. Per això, tonant al , puntualitzem que mitjançant l'atenta mirada d'Ernesto Halffter al Pare Soler en la Sinfonietta es manté també una associació estil·lística amb el clavicenista napolità.

Forma i estructura
Les diferents formes que s'estableixen en l'obra d'Ernesto Halffter són les ja predominants dins la segona meitat del segle XVIII: quatre moviments: el primer una forma sonata, el segon un lento, el tercer un minuetto i el quart un rondó o una altra forma sonata (alguns ho consideren com un rondó-sonata).

L'estructura de la Sinfonietta de Halffter té unes clares semblances a les obres cambrístiques de Boccherini, per la disposició dels diferents moviments en els que s'estableix el citat ordre de quatre moviments. Cal destacar l'apropament, de forma molt discreta, de la música popular. No estem parlant d'un nacionalisme fàcil, sinó d'un nacionalisme despullat d'artificis, d'afegits que embrutin la claredat de la música pura, clàssica en el sentit conceptual de la paraula. Tot i això, hi ha fragments, com en el desenvolupament del primer moviment o en algunes parts de l'últim, en els que hi ha associacions al casticisme, amb girs molt andalusos.

Es pot apreciar molt clarament la formació d'una orquestra de cambra. És una obra idònia per a ser interpretada per grans solistes. Per altra banda, l'aparició dels tres solistes ens recorden als Concerti grossi del Barroc. I és per això mateix que tampoc es descarta de forma taxativa la visió del barroc tardà en alguns aspectes més ocults de la Sinfonietta, com és en aquest cas la distribució sonora.

Instrumentació
Val la pena dir la instrumentació utilitzada per Halffter en aquesta obra i que és la següent (trascrita directament de la partitura):

Comentaris estilístics sobre l'obra
L'obra comença de forma imponent i rica en timbres, apareixent en molt pocs compassos tots els instruments, amb cordes dobles, redobles de tambor, i unes línies sonores molt clares. La tonalitat de Re major està establerta just al començar.

Pastoral
Partim de la idea que l'estructura de l'exposició del primer moviment de la Sinfonietta pot ser interpretada de dues maneres: o bé entenent que està integrada per dos grups de temes diferents o per altra banda que aquests dos temes provenen del mateix material temàtic, amb algunes variants afegides.

S'inicia l'obra amb la "Pastorela". El tema A d'aquesta apareix en les tres seccions de l'exposició, tot i això, no apareix exactament igual a la reexposició..

En ser el moviment politemàtic, s'associa més fàcilment al Classicisme que al període de Barroc tardà. No obstant, no podem oblidar que la Simfonietta de Halffter és una obra neoclàssica no clàssica o de barroc tardà, sense haver per tant d'imitar literalment alguna d'aquestes dues corrents.

La part central del desenvolupament s'allunya de l'atmosfera neoclàssica a una més aviat nacionalista. El resultat és molt exòtic, amb una barreja d'escala de tons al ascendir, i baixar amb una escala frigia. Els ornaments i el redoble del tambor petit accentuen les referències "andaluses".

Adagio
L'Adagio te l'estructura de la forma lenta tripartita (A-B-A'). En aquest moviment podem apreciar un caràcter monotemàtic que apareix de nou en moltes formes del barroc tardà i també clàssiques, com en algunes obres de Joseph Haydn.

Es pot observar un tema principal, amb el que es fan algunes variants durant el discurs expositiu. Abans i després del tema principal hi ha, respectivament, un tema introductiu i un tema episòdic, sense arribar a tenir cap dels dos una importància transcendental en l'exposició.

Allegro vivace
El tercer moviment és un minuetto-trío. és el més clar i senzill d'entendre, tant la seva estructura com la pròpia orquestració. Pràcticament no hi ha modulacions.

Al igual que les formes anteriors, el minuetto s'estableix en tres seccions sent la segona un Trío i la tercera un simple volta sense repetició a la primera.

Allegro giocoso
És un rondó-sonata, aquesta forma té l'estructura global d'un primer moviment de sonata en tres parts, sense oblidar per altra banda la peculiaritat d que el seu desenvolupament està protagonitzat per un nou tema per a després tornar a la primera secció.

El jovial i festiu estan presents des dels primers compassos d'aquest "Allegro giocoso". Subconscientment, pot relacionar-se amb algunes antigues festes populars d'Espanya. En varis moments d'aquest últim moviment sembla que hi ha una intenció d'autor per imitar el rasqueig d'una guitarra.

Crítica i estrena
A continuació hi ha dues ressenyes periodístiques publicades el 6 d'abril de 1927, i referides a la seva estrena, la qual passà el dia anterior. Aquestes crítiques pertanyen a Adolfo Salazar (El Sol, Madrid) i a Juan Brezo (La Voz, Madrid).

<...mientras en Halffter es artículo de fe la adhesión sustancial a toda la gran música del pasado- el sentimiento consciente de la "continuidad histórica"-, los músicos extranjeros de su edad creyeron preferible cortar todo lazo de unión con sus antecesores..., para volver en seguida mohinos por la esclera de servicios>.

És comprensible que la crítica escrita d'Adolfo Salazar provoqués polèmica, sense ocultar els seus pensaments més personals: molts d'ells arrebossats d'entusiasme, i altres llançats com fletxes per a respondre de forma antagònica.

De forma més compromesa, el mateix articulista confronta a Halffter amb Stravinsky:

<...mientras éste [Stravisky] toma directamenta el texto de Pergolesi y lo inyecta de sustancias modernas Halffter al revés, viste su propia modernidad de un ropaje exterior cuyo color de influencia evoca más o menos claramente, el siglo XVIII. El resultado es de una belleza imonderable>.

També fou molt positiva la crítica de Mantecón de l'estrenada simfonietta.

<...nada hay inútil ni vacío en esta obra de Halffter; todo llega con exigencias de necesidad, y como en él, la flora variadísima que lo puebla no surge arbitraria y caprichosa sino dentro de un plan y orden que presentimos, sin necesidad de analizar; ^[...]

El ayer en la Sinfonietta" el rico contenido melódico que mira hacia Mozart la frondosa polifonía que se engancha en Bach; lo actual es su vestido armónico e instrumental, acaso su lógica constructiva; [...]>.

Bibliografia
 ACKER, Yolanda i SUÁREZ-PAJARES, Javier; Ernesto Halffter (1905-1989): Música en dos tiempos. Madrid, Publicaciones de la Revista de Estudiantes, 1997.
 ÁLVAREZ, Alberto J: La Sinfonietta de Ernesto Halffter y las formas preclásicas (2005). Anuario musical, No 60.
 ÁLVAREZ, Alberto: Análisis de la sinfonietta en Re de Ernesto Halfter. Ediciones maestro, 2007
 COSTAS, Gerardo; La generacion musical del 27, a l'Estafeta Literaria, 618-619 (1997), pg. 34-36.

Referències

Simfonies
Obres del 1927
Simfonies de la dècada del 1920
Composicions en re major


text:
Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors
First Posted : December 4, 2007
Results First Posted : July 21, 2017
Last Update Posted : August 21, 2017
Radiation Therapy Oncology Group
National Cancer Institute (NCI)
NRG Oncology
RATIONALE: Memantine may be able to decrease side effects caused by whole-brain radiation therapy. It is not yet known if memantine is effective in preventing side effects caused by whole-brain radiation therapy.
PURPOSE: This randomized phase III trial is studying memantine to see how well it works compared to a placebo in preventing side effects caused by whole-brain radiation therapy in patients with brain metastases from solid tumors.
Cognitive/Functional Effects Metastatic Cancer Neurotoxicity Unspecified Adult Solid Tumor, Protocol Specific Drug: Memantine Other: Placebo Radiation: Whole brain radiation therapy Phase 3
Determine whether the addition of memantine hydrochloride to whole-brain radiotherapy (WBRT) preserves cognitive function, specifically memory, as measured by the Hopkins Verbal Learning Test for delayed recall (HVLT-delayed recall), over that of placebo and WBRT in patients with brain metastases at 24 weeks from the start of drug treatment.
Determine whether the addition of memantine hydrochloride preserves cognitive function, specifically memory, as measured by the HVLT-delayed recall at 8 weeks, 16 weeks, and 12 months from the start of drug treatment.
Determine whether the addition of memantine hydrochloride increases time to neurocognitive failure as measured by cognitive decline on a battery of tests including the HVLT for free recall, delayed recall, and delayed recognition; the Controlled Word Association Test (COWAT); the Trail Making Test Parts A and B (TMT); the Medical Outcomes Scale-Cognitive Functioning Subscale (MOS); and the Mini-Mental Status Examination (MMSE).
Evaluate the potential benefit of memantine hydrochloride in change and overall quality of life, as measured by the Functional Assessment of Cancer Therapy-Brain (FACT-Br) subscale.
Determine whether the addition of memantine hydrochloride increases progression-free survival.
Determine whether the addition of memantine hydrochloride increases overall survival.
Compare adverse events between the treatment arms according to the CTCAE v3.0 criteria.
Collect serum, plasma, buffy coat cells, urine, and cerebrospinal fluid (CSF) for future translational research analyses.
OUTLINE: This is a multicenter study. Patients are stratified according to recursive partitioning analysis (RPA) prognostic class (class I vs class II with controlled systemic disease) and prior surgical therapy (none vs radiosurgery or surgical resection). Patients are randomized to 1 of 2 treatment arms.
Arm I: Patients undergo whole-brain radiotherapy (WBRT) 5 days a week for 3 weeks (15 fractions). Patients also receive oral memantine hydrochloride once daily beginning on day 1 of WBRT and continuing for 24 weeks.
Arm II: Patients undergo WBRT as in arm I. Patients also receive oral placebo once daily beginning on day 1 of WBRT and continuing for 24 weeks.
After completion of study treatment, patients are followed at 6 months, every 4 months for 1 year, every 6 months for 2 years, and then annually thereafter.
Masking: Double (Participant, Investigator)
Primary Purpose: Supportive Care
Official Title: A Randomized, Phase III, Double-Blind, Placebo-Controlled Trial of Memantine for Prevention of Cognitive Dysfunction in Patients Receiving Whole-Brain Radiotherapy
Study Start Date : March 2008
Actual Primary Completion Date : April 2011
Actual Study Completion Date : December 2016
Drug Information available for: Memantine Memantine hydrochloride
Genetic and Rare Diseases Information Center resources: Neurotoxicity Syndromes
Experimental: WBRT+Memantine
Whole brain radiation therapy (WBRT) and memantine
Drug: Memantine
Patients began taking memantine(by mouth) while receiving radiation therapy. Patients continued taking memantine for 24 weeks or until doctor thinks it is in their best interest to stop. They started with 5 mg once a day. After a week dose increased to 5 mg twice a day. At week 3, dose increased to 10 mg in the morning and 5 mg in the evening. Weeks 4-24, dose was 10 mg twice a day.
Radiation: Whole brain radiation therapy
Whole brain radiation therapy (WBRT) once a day (2.5Gy), five days a week (Monday to Friday) for three weeks, for total fifteen treatments and 37.5 Gy
Active Comparator: WBRT+Placebo
Whole brain radiation therapy (WBRT) and placebo
Other: Placebo
Patients began taking placebo(by mouth) while receiving radiation therapy. Patients continued taking placebo for 24 weeks or until doctor thinks it is in their best interest to stop. They started with 5 mg once a day. After a week dose increased to 5 mg twice a day. At week 3, dose increased to 10 mg in the morning and 5 mg in the evening. Weeks 4-24, dose was 10 mg twice a day.
Change in the Hopkins Verbal Learning Test - Revised for Delayed Recall (HVLT-R-delayed Recall) at 24 Weeks [ Time Frame: Baseline and 24 weeks from the start of drug treatment ]
The HVLT-R consists of 3 parts. Free call has a range of 0 to 36, delayed recall has a range from 0 to 12, and delayed recognition has a range of -12 to 12. Higher scores indicating better function in all 3 parts. Standardized scores are used by calculating an average standardized z score for each part of the HVLT-R. Change is calculated by subtracting baseline value from 24-week value. Imputation methods were used to determine values for all alive patients missing the 24 week assessment. This tool is being used to measure cognitive function, specifically memory.
Change in the Hopkins Verbal Learning Test - Revised for Delayed Recall (HVLT-R-delayed Recall) at 8, 16, and 52 Weeks [ Time Frame: Baseline, 8, 16, and 52 weeks from the start of drug treatment ]
The HVLT-R consists of 3 parts. Free call has a range of 0 to 36, delayed recall has a range from 0 to 12, and delayed recognition has a range of -12 to 12. Higher scores indicating better function in all 3 parts. Standardized scores are used by calculating an average standardized z score for each part of the HVLT-R. Change is calculated by subtracting baseline value from the respective later time point value. Imputation methods were used to determine values for all alive patients missing the post-baseline assessments. This tool is being used to measure cognitive function, specifically memory.
Median Time to Neurocognitive Failure [ Time Frame: Baseline to 12 months from the start of drug treatment ]
Neurocognitive failure is defined as the first cognitive failure on any of the neurocognitive tests: the HVLT-R for immediate recall, delayed recognition, and delayed recall; the Controlled Oral Word Association Test (COWAT); the Trail-Making Test (TMT) Parts A and B. Cognitive failure for each test is defined as a post-treatment score that meets one of the following criteria: follow-up score is at least 2 standard deviations worse than the patient's personal baseline score or the patient's raw score change is greater than the reliable change index. The cumulative incidence approach was used to estimate the median time to neurocognitive failure to account for the competing risks of disease progression and death.
Change in Functional Assessment of Cancer Therapy With Brain Subscale (FACT-Br) at 24 Weeks [ Time Frame: Baseline and 24 weeks from start of treatment ]
The FACT-Br is a 50-question self-report questionnaire contains the following domains (scales): Physical well-being (7 questions), social/family well-being (7 questions), emotional well-being (6 questions), functional well-being (7 questions) and brain cancer subscale which contains concerns relevant to patients with brain tumors (23 questions). Each question has a value 0-4. For some questions a higher indicates better outcome and others are the opposite. The former are summed as is, the latter are reversed in value before adding, such that each domain ranges from 0 to 4 times the number of questions in the domain, with 0 indicating worst and the highest possible value indicating best outcome. The FACT-Br total is obtained by adding all domains together if the overall question response rate is greater than 80%. Total scores on the FACT-Br range from 0 to 184 with lower scores indicating declining quality of life. Change is calculated as baseline score subtracted from 24-week score.
Median Progression-free Survival Time [ Time Frame: From randomization to date of progression, death or last follow-up. Analysis occurs at the same time as the primary outcome. Patients are followed until death and all follow-up collected at time of analysis is used. ]
Disease progression is defined as the first of the following events: an increase of at least 50% for lesions less than or equal to 1cm, an increase of least 25% for lesions greater than 1cm, appearance of any new brain metastases. Failure for progression-free survival is disease progression or death. Median progression-free survival was estimated using the Kaplan-Meier method.
Overall Survival [ Time Frame: From randomization to date of death or last follow-up. Analysis occurs at the same time as the primary outcome. Patients are followed until death and all follow-up collected at time of analysis is used. ]
Failure for overall survival is death from any cause. Median survival was estimated using the Kaplan-Meier method.
Ages Eligible for Study: 18 Years to 120 Years (Adult, Older Adult)
DISEASE CHARACTERISTICS:
Histologically or cytologically confirmed diagnosis of a solid tumor malignancy within the past 5 years
If the original histologic proof of malignancy is > 5 years, then pathological (i.e., more recent) confirmation is required (e.g., from a systemic metastasis or brain metastasis)
Brain metastases must be visible on contrast-enhanced MRI or a contrast enhanced CT scan (for patients unable to undergo MRI within the past 28 days)
Patients unable to undergo MRI imaging because of non-compatible devices are eligible, provided the contrast-enhanced CT scans are obtained and are of sufficient quality
Patients who had undergone radiosurgery or surgical resection and are planning adjuvant whole-brain radiotherapy do not have to have visible disease but do need a baseline MRI
Must have stable systemic disease (i.e. no evidence of systemic disease progression within the past 3 months)
Patients with brain metastases at initial presentation are eligible and do not need to demonstrate 3 months of stable scans
PATIENT CHARACTERISTICS:
Karnofsky performance status 70-100%
Serum creatinine ≤ 3 mg/dL and creatinine clearance ≥ 30 mL/min
Total bilirubin ≤ 2.5 mg/dL
Blood urea nitrogen (BUN) < 20 mg/dL
Mini-mental status exam score ≥ 18
Negative serum pregnancy test
Fertile patients must practice adequate contraception
Severe, active co-morbidity, defined as follows:
Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months
Transmural myocardial infarction within the last 6 months
Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration
Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of registration
Hepatic insufficiency resulting in clinical jaundice and/or coagulation defects
Pregnant or lactating women
Prior allergic reaction to memantine hydrochloride
Current alcohol or drug abuse
Intractable seizures while on adequate anticonvulsant therapy (i.e., more than one seizure per month for the past 2 months)
PRIOR CONCURRENT THERAPY:
At least 14 days but no more than 56 days since prior therapy for brain metastasis, including radiosurgery and surgical resection
No systemic chemotherapy for 14 days prior, during, or for 14 days after completion of whole-brain radiotherapy (WBRT)
Prior cranial radiotherapy
Patients may have received up to 3 prior WBRT treatments and still be registered and randomized on the protocol provided WBRT parameters meet protocol requirements
Chronic short-acting benzodiazepine use
Show 235 study locations Hide 235 study locations
United States, Alabama
MBCCOP - Gulf Coast
Mobile, Alabama, United States, 36604
Providence Cancer Center at Providence Hospital
United States, Arizona
Arizona Oncology Services Foundation
Phoenix, Arizona, United States, 85013
Mayo Clinic Scottsdale
Scottsdale, Arizona, United States, 85259-5499
Arizona Oncology - Tucson
Tucson, Arizona, United States, 85704
Arizona Cancer Center at University of Arizona Health Sciences Center
Tucson, Arizona, United States, 85724-5024
Auburn Radiation Oncology
Auburn, California, United States, 95603
Providence Saint Joseph Medical Center - Burbank
Burbank, California, United States, 91505
Radiation Oncology Centers - Cameron Park
Cameron Park, California, United States, 95682
Mercy Cancer Center at Mercy San Juan Medical Center
Carmichael, California, United States, 95608
Enloe Cancer Center at Enloe Medical Center
Chico, California, United States, 95926
Cancer Care Center at John Muir Health - Concord Campus
Concord, California, United States, 94524-4110
City of Hope Comprehensive Cancer Center
Duarte, California, United States, 91010-3000
Glendale Adventist Medical Center
Glendale, California, United States, 91206
Rebecca and John Moores UCSD Cancer Center
La Jolla, California, United States, 92093-0658
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
USC/Norris Comprehensive Cancer Center and Hospital
Los Angeles, California, United States, 90089-9181
St. Joseph Hospital Regional Cancer Center - Orange
Orange, California, United States, 92868
Radiation Oncology Center - Roseville
Roseville, California, United States, 95661
Radiological Associates of Sacramento Medical Group, Incorporated
Sacramento, California, United States, 95815
University of California Davis Cancer Center
Stanford Cancer Center
Stanford, California, United States, 94305-5824
Emanuel Regional Cancer Services at Emanuel Medical Center
Turlock, California, United States, 95382
Solano Radiation Oncology Center
Vacaville, California, United States, 95687
John Muir/Mt. Diablo Comprehensive Cancer Center
Walnut Creek, California, United States, 94598
United States, Colorado
Rocky Mountain Cancer Centers - Aurora
Aurora, Colorado, United States, 80012
Rocky Mountain Cancer Centers - Colorado Springs
Colorado Springs, Colorado, United States, 80909
Poudre Valley Radiation Oncology
Fort Collins, Colorado, United States, 80528
United States, Connecticut
New Haven, Connecticut, United States, 06520-8028
United States, Delaware
CCOP - Christiana Care Health Services
Newark, Delaware, United States, 19713
United States, District of Columbia
Washington Cancer Institute at Washington Hospital Center
Washington, D.C., District of Columbia, United States, 20010
University of Florida Shands Cancer Center
Gainesville, Florida, United States, 32610-0232
Integrated Community Oncology Network
Jacksonville Beach, Florida, United States, 32250
Baptist Cancer Institute - Jacksonville
Jacksonville, Florida, United States, 32207
Integrated Community Oncology Network at Southside Cancer Center
Baptist Medical Center South
Integrated Community Oncology Network - Orange Park
Orange Park, Florida, United States, 32073
Florida Institute of Research, Medicine and Surgery Cancer Center
Orlando, Florida, United States, 32806
Florida Cancer Center - Palatka
Palatka, Florida, United States, 32177
Flagler Cancer Center
Saint Augustine, Florida, United States, 32086
Winship Cancer Institute of Emory University
Atlanta, Georgia, United States, 30322
John B. Amos Cancer Center
Columbus, Georgia, United States, 31904
Veterans Affairs Medical Center - Atlanta (Decatur)
Northeast Georgia Medical Center
Gainesville, Georgia, United States, 30501
United States, Illinois
Northwest Community Hospital
Arlington Heights, Illinois, United States, 60005
Chicago, Illinois, United States, 60612-3785
Cancer Institute at St. John's Hospital
Springfield, Illinois, United States, 62702
CCOP - Carle Cancer Center
Urbana, Illinois, United States, 61801
United States, Indiana
Saint John's Cancer Center at Saint John's Medical Center
Anderson, Indiana, United States, 46016
Bloomington Hospital Regional Cancer Institute
Bloomington, Indiana, United States, 47403
Radiation Oncology Associates Southwest
Fort Wayne, Indiana, United States, 46804
Parkview Regional Cancer Center at Parkview Health
Center for Cancer Care at Goshen General Hospital
Goshen, Indiana, United States, 46526
Indiana University Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, United States, 46202-5289
Methodist Cancer Center at Methodist Hospital
Indianapolis, Indiana, United States, 46202
Central Indiana Cancer Centers - East
Community Regional Cancer Care at Community Hospital East
Community Regional Cancer Care at Community Hospital North
Cancer Center at Ball Memorial Hospital
Muncie, Indiana, United States, 47303-3499
CCOP - Northern Indiana CR Consortium
South Bend, Indiana, United States, 46601
United States, Iowa
Holden Comprehensive Cancer Center at University of Iowa
Iowa City, Iowa, United States, 52242-1002
Kansas City Cancer Centers - Southwest
Overland Park, Kansas, United States, 66210
Lucille P. Markey Cancer Center at University of Kentucky
Lexington, Kentucky, United States, 40536-0093
Norton Suburban Hospital
Louisville, Kentucky, United States, 40207
United States, Maryland
Greenebaum Cancer Center at University of Maryland Medical Center
Baltimore, Maryland, United States, 21201
St. Agnes Hospital Cancer Center
Harry and Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
Good Samaritan Hospital of Maryland
Central Maryland Oncology Center
Columbia, Maryland, United States, 21044
Tate Cancer Center at Baltimore Washington Medical Center
Glen Burnie, Maryland, United States, 21061
Cancer Institute at St. Joseph Medical Center
Towson, Maryland, United States, 21204
Boston University Cancer Research Center
Charach Cancer Center at Huron Valley - Sinai Hospital
Commerce, Michigan, United States, 48382
Barbara Ann Karmanos Cancer Institute
Detroit, Michigan, United States, 48201-1379
Josephine Ford Cancer Center at Henry Ford Hospital
Detroit, Michigan, United States, 48202
Great Lakes Cancer Institute at McLaren Regional Medical Center
Flint, Michigan, United States, 48532
CCOP - Grand Rapids
Grand Rapids, Michigan, United States, 49503
St. Mary Mercy Hospital
Livonia, Michigan, United States, 48154
William Beaumont Hospital - Royal Oak Campus
Royal Oak, Michigan, United States, 48073
Albert Lea Cancer Center at Albert Lea Medical Center
Albert Lea, Minnesota, United States, 56007
Burnsville, Minnesota, United States, 55337
Mercy and Unity Cancer Center at Mercy Hospital
Coon Rapids, Minnesota, United States, 55433
Edina, Minnesota, United States, 55435
Mercy and Unity Cancer Center at Unity Hospital
Fridley, Minnesota, United States, 55432
Immanuel St. Joseph's
Mankato, Minnesota, United States, 56002
Minnesota Oncology Hematology, PA - Maplewood
Maplewood, Minnesota, United States, 55109
Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
Robbinsdale, Minnesota, United States, 55422-2900
Rochester, Minnesota, United States, 55905
CentraCare Clinic - River Campus
Saint Cloud, Minnesota, United States, 56303
CCOP - Metro-Minnesota
Saint Louis Park, Minnesota, United States, 55416
Saint Paul, Minnesota, United States, 55102
Waconia, Minnesota, United States, 55387
United States, Mississippi
Regional Cancer Center at Singing River Hospital
Pascagoula, Mississippi, United States, 39581
United States, Missouri
Kansas City Cancer Centers - South
Kansas City, Missouri, United States, 64131
Kansas City Cancer Centers - North
CCOP - St. Louis-Cape Girardeau
Saint Louis, Missouri, United States, 63141
Hulston Cancer Center at Cox Medical Center South
Springfield, Missouri, United States, 65807
United States, Montana
CCOP - Montana Cancer Consortium
Billings, Montana, United States, 59101
Northern Rockies Radiation Oncology Center
Billings Clinic - Downtown
Billings, Montana, United States, 59107-7000
United States, Nebraska
Methodist Estabrook Cancer Center
Omaha, Nebraska, United States, 68114
Nebraska Medical Center
United States, Nevada
CCOP - Nevada Cancer Research Foundation
Las Vegas, Nevada, United States, 89106
Renown Institute for Cancer at Renown Regional Medical Center
Reno, Nevada, United States, 89502
United States, New Hampshire
Payson Center for Cancer Care at Concord Hospital
Concord, New Hampshire, United States, 03301
Elliot Regional Cancer Center at Elliot Hospital
Manchester, New Hampshire, United States, 03103
Ocean Medical Center at Meridian Health
Bricktown, New Jersey, United States, 08724
Cancer Institute of New Jersey at Cooper University Hospital - Camden
Camden, New Jersey, United States, 08103
Trinitas Comprehensive Cancer Center at Trinitas Hospital
Elizabeth, New Jersey, United States, 07207
Princeton Radiation Oncology Center
Jamesburg, New Jersey, United States, 08831
Saint Peter's University Hospital
New Brunswick, New Jersey, United States, 08901
University Medical Center at Princeton
Princeton, New Jersey, United States, 08540-3298
J. Phillip Citta Regional Cancer Center at Community Medical Center
Toms River, New Jersey, United States, 08755
Cancer Institute of New Jersey at Cooper - Voorhees
Voorhees, New Jersey, United States, 08043
United States, New Mexico
Lovelace Medical Center - Downtown
Albuquerque, New Mexico, United States, 87102
Radiation Oncology Associates, PA
University of New Mexico Cancer Center
Albuquerque, New Mexico, United States, 87131-5636
New York Oncology Hematology, PC at Albany Regional Cancer Care
Albany, New York, United States, 12206
Veterans Affairs Medical Center - Albany
New York Methodist Hospital
Brooklyn, New York, United States, 11215
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263-0001
Sands Cancer Center
Canandaigua, New York, United States, 14424
CCOP - North Shore University Hospital
Manhasset, New York, United States, 11030
Long Island Jewish Medical Center
New Hyde Park, New York, United States, 11040
Highland Hospital of Rochester
Rochester, New York, United States, 14620
Lipson Cancer and Blood Center at Rochester General Hospital
University Radiation Oncology at Parkridge Hospital
James P. Wilmot Cancer Center at University of Rochester Medical Center
Mission Hospitals - Memorial Campus
Asheville, North Carolina, United States, 28801
New Hanover Radiation Oncology, PA
Wilmington, North Carolina, United States, 28401
United States, North Dakota
Trinity CancerCare Center
Minot, North Dakota, United States, 58701
McDowell Cancer Center at Akron General Medical Center
Akron, Ohio, United States, 44307
Summa Center for Cancer Care at Akron City Hospital
Akron, Ohio, United States, 44309-2090
Barberton Citizens Hospital
Barberton, Ohio, United States, 44203
Charles M. Barrett Cancer Center at University Hospital
Cleveland Clinic Cancer Center at Fairview Hospital
Cleveland, Ohio, United States, 44111
Cleveland Clinic Taussig Cancer Center
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210-1240
Cleveland Clinic Cancer Center
Independence, Ohio, United States, 44131
Northwest Ohio Oncology Center
Maumee, Ohio, United States, 43537-1839
Hillcrest Cancer Center at Hillcrest Hospital
Mayfield Heights, Ohio, United States, 44124
St. Charles Mercy Hospital
Oregon, Ohio, United States, 43616
Cancer Care Center, Incorporated
Salem, Ohio, United States, 44460
North Coast Cancer Care, Incorporated
Sandusky, Ohio, United States, 44870
Flower Hospital Cancer Center
Sylvania, Ohio, United States, 43560
Medical University of Ohio Cancer Center
Toledo, Ohio, United States, 43614
CCOP - Toledo Community Hospital
St. Anne Mercy Hospital
Precision Radiotherapy at University Pointe
West Chester, Ohio, United States, 45069
Cancer Treatment Center
Wooster, Ohio, United States, 44691
Cleveland Clinic - Wooster
United States, Oklahoma
Oklahoma University Cancer Institute
Oklahoma City, Oklahoma, United States, 73104
Willamette Valley Cancer Center - Eugene
Eugene, Oregon, United States, 97401
Three Rivers Community Hospital
Grants Pass, Oregon, United States, 97527
Dubs Cancer Center at Rogue Valley Medical Center
Medford, Oregon, United States, 97504
Providence Cancer Center at PMCC
Rosenfeld Cancer Center at Abington Memorial Hospital
Abington, Pennsylvania, United States, 19001
UPMC Cancer Center at Beaver Medical Center
Beaver, Pennsylvania, United States, 15009
St. Luke's Cancer Network at St. Luke's Hospital
Bethlehem, Pennsylvania, United States, 18015
Bryn Mawr Hospital
Bryn Mawr, Pennsylvania, United States, 19010
UPMC Cancer Center at Jefferson Regional Medical Center
Clairton, Pennsylvania, United States, 15025
Cancer Center at Clarion Hospital
Clarion, Pennsylvania, United States, 16214
Geisinger Cancer Institute at Geisinger Health
Danville, Pennsylvania, United States, 17822-0001
Delaware County Regional Cancer Center at Delaware County Memorial Hospital
Drexel Hill, Pennsylvania, United States, 19026
Northeast Radiation Oncology Center
Dunmore, Pennsylvania, United States, 18512
Adams Cancer Center
Gettysburg, Pennsylvania, United States, 17325
UPMC Cancer Center - Arnold Palmer Pavilion
Greensburg, Pennsylvania, United States, 15601
Cherry Tree Cancer Center
Hanover, Pennsylvania, United States, 17331
Penn State Cancer Institute at Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States, 17033-0850
UPMC Cancer Center at the John P. Murtha Pavilion
Johnstown, Pennsylvania, United States, 15901
UPMC Cancer Center at UPMC McKeesport
McKeesport, Pennsylvania, United States, 15132
UPMC - Moon
Moon, Pennsylvania, United States, 15108
UPMC Cancer Center - Natrona Heights
Natrona Heights, Pennsylvania, United States, 15065
Jameson Memorial Hospital - North Campus
New Castle, Pennsylvania, United States, 16105
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
Philadelphia, Pennsylvania, United States, 19107-5541
Fox Chase Cancer Center - Philadelphia
Albert Einstein Cancer Center
Philadelphia, Pennsylvania, United States, 19141
UPMC - Shadyside
Pittsburgh, Pennsylvania, United States, 15213-2582
UPMC Cancer Center at Magee-Womens Hospital
UPMC Cancer Center at UPMC St. Margaret
UPMC Cancer Center at UPMC Passavant
UPMC Cancer Center - Upper St. Clair
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, United States, 16346
UPMC Cancer Center - Uniontown
Uniontown, Pennsylvania, United States, 15401
Washington Hospital Cancer Center
Washington, Pennsylvania, United States, 15301
Lankenau Cancer Center at Lankenau Hospital
Wynnewood, Pennsylvania, United States, 19096
York Cancer Center at Apple Hill Medical Center
York, Pennsylvania, United States, 17405
United States, South Carolina
Hollings Cancer Center at Medical University of South Carolina
Charleston, South Carolina, United States, 29425
CCOP - Upstate Carolina
Spartanburg, South Carolina, United States, 29303
United States, South Dakota
Rapid City Regional Hospital
Rapid City, South Dakota, United States, 57701
Texas Oncology, PA at Texas Cancer Center - Arlington South
Arlington, Texas, United States, 76014
Texas Oncology, PA at Harris Center HEB
Bedford, Texas, United States, 76022
Medical City Dallas Hospital
Dallas, Texas, United States, 75230
Texas Oncology, PA at Texas Cancer Center Dallas Southwest
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
Texas Oncology, PA at Texas Cancer Center - Denton South
Denton, Texas, United States, 76210
Klabzuba Cancer Center at Harris Methodist Fort Worth Hospital
Fort Worth, Texas, United States, 76104
Longview Cancer Center
Longview, Texas, United States, 75601
West Texas Cancer Center
Odessa, Texas, United States, 79761
Cancer Care Centers of South Texas - Northeast
San Antonio, Texas, United States, 78229-3900
Texas Oncology, PA at Texas Cancer Center - Sherman
Sherman, Texas, United States, 75090
Texas Oncology, PA at Texas Oncology Cancer Center Sugar Land
Sugar Land, Texas, United States, 77479
Tyler Cancer Center
Tyler, Texas, United States, 75702
United States, Utah
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center
Murray, Utah, United States, 84157
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center
Ogden, Utah, United States, 84403
Dixie Regional Medical Center - East Campus
Saint George, Utah, United States, 84770
Utah Cancer Specialists at UCS Cancer Center
Salt Lake City, Utah, United States, 84106
Huntsman Cancer Institute at University of Utah
United States, Vermont
Fletcher Allen Health Care - University Health Center Campus
Burlington, Vermont, United States, 05401
United States, Virginia
University of Virginia Cancer Center
Charlottesville, Virginia, United States, 22908
Sentara Cancer Institute at Sentara Norfolk General Hospital
Norfolk, Virginia, United States, 23507
United States, Washington
CCOP - Virginia Mason Research Center
Seattle, Washington, United States, 98101
Cancer Care Northwest - Spokane South
Spokane, Washington, United States, 99202
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima, Washington, United States, 98902
United States, West Virginia
Schiffler Cancer Center at Wheeling Hospital
Wheeling, West Virginia, United States, 26003
United States, Wisconsin
Theda Care Cancer Institute
Appleton, Wisconsin, United States, 54911
St. Vincent Hospital Regional Cancer Center
Green Bay, Wisconsin, United States, 54307-3508
Franciscan Skemp Healthcare - La Crosse Campus
La Crosse, Wisconsin, United States, 54601
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
Madison, Wisconsin, United States, 53792-6164
Bay Area Cancer Care Center at Bay Area Medical Center
Marinette, Wisconsin, United States, 54143
Community Memorial Hospital Cancer Care Center
Menomonee Falls, Wisconsin, United States, 53051
Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center
Milwaukee, Wisconsin, United States, 53215
Medical College of Wisconsin Cancer Center
All Saints Cancer Center at Wheaton Franciscan Healthcare
Racine, Wisconsin, United States, 53405
University of Wisconcin Cancer Center at Aspirus Wausau Hospital
Wausau, Wisconsin, United States, 54401
West Allis Memorial Hospital
West Allis, Wisconsin, United States, 53227
Canada, Nova Scotia
Nova Scotia Cancer Centre
Halifax, Nova Scotia, Canada, B3H 1V8
London Regional Cancer Program at London Health Sciences Centre
London, Ontario, Canada, N6A 4L6
Canada, Quebec
Maisonneuve-Rosemont Hospital
Montreal, Quebec, Canada, H1T 2M4
Hopital Notre-Dame du CHUM
Montreal, Quebec, Canada, H2L 4M1
McGill Cancer Centre at McGill University
Montreal, Quebec, Canada, H2W 1S6
Centre Hospitalier Universitaire de Quebec
Quebec City, Quebec, Canada, G1R 2J6
Principal Investigator: Paul D. Brown, MD Mayo Clinic
Study Chair: Christina A. Meyers, PhD M.D. Anderson Cancer Center
Study Chair: Sherry Fox, RN, PhD Bon Secours Cancer Institute at St. Mary's Hospital
Study Chair: Deepak Khuntia, MD University of Wisconsin, Madison
Manuscript for primary analysis results
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Brown PD, Pugh S, Laack NN, Wefel JS, Khuntia D, Meyers C, Choucair A, Fox S, Suh JH, Roberge D, Kavadi V, Bentzen SM, Mehta MP, Watkins-Bruner D; Radiation Therapy Oncology Group (RTOG). Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial. Neuro Oncol. 2013 Oct;15(10):1429-37. doi: 10.1093/neuonc/not114. Epub 2013 Aug 16.
Responsible Party: Radiation Therapy Oncology Group
Other Study ID Numbers: RTOG-0614
CDR0000577872
NCI-2009-00735 ( Registry Identifier: CTRP (Clinical Trial Reporting Program) )
First Posted: December 4, 2007 Key Record Dates
Results First Posted: July 21, 2017
Last Update Posted: August 21, 2017
Keywords provided by Radiation Therapy Oncology Group:
cognitive/functional effects
tumors metastatic to brain
unspecified adult solid tumor, protocol specific
Neurotoxicity Syndromes
Chemically-Induced Disorders
Antiparkinson Agents
Anti-Dyskinesia Agents
Dopamine Agents
Excitatory Amino Acid Antagonists
Excitatory Amino Acid Agents


169 records – page 1 of 4.
Market rates [textual record] – 1959-1972.
Piece-work rates [textual record] – 1947-1956.
Vest rates [textual record] – 1936-1941.
Pant and vest contractor prices [textual record] – 1947-1961.
Consumer price index [textual record] – 1954-1969.
Financial statements [textual record] – 1966-1967.
Financial statements [textual record] – 1969-1970.
Financial statements [textual record] – 1970-1971.
Financial statements [textual record] – 1971-1972.
Financial statements [textual record] – 1972-1973.
Financial statements [textual record] – 1973-1974.
Financial statements [textual record] – 1974-1975.
Financial statements [textual record] – 1975-1976.
Financial statements [textual record] – 1976-1977.
Financial statements [textual record] – 1978-1979.
Financial statements [textual record] – 1980-1981.
Financial statements [textual record] – 1981-1982.
Financial statements [textual record] – 1982-1983.
Financial statements [textual record] – 1983-1984.
Dues assessments [textual record] – 1969-1970.
Dues assessments [textual record] – 1970-1971.
Dues assessments [textual record] – 1971-1972.
Dues assessments [textual record] – 1972-1973.
Dues assessments [textual record] – 1973-1974.
Dues assessments [textual record] – 1974-1975.
Dues assessments [textual record] – 1975-1976.
Dues assessments [textual record] – 1976-1977.
Dues assessments [textual record] – 1978.
Dues assessments revision [textual record] – 1968-1969.
Dues assessments [textual record] – 1978-1980.
Benefit and retirement funds [textual record] – 1955.
Budget and Finance Committee [textual record] – 1938-1983.
Series consists of three sub-series; Meeting Minutes; Budget Reports, Submissions and Planning Information; and General Ledgers. These records document the activities of the Budget and Finance Committee while managing the major financial responsibilities of the UJWF. Files are arranged chronologically within each sub-series.
See Fonds 66, Series 7, for records of the Budget Committee of the predecessor organization, the Federation of Jewish Philanthropies of Toronto.
Meeting Minutes [textual record] – 1938-1983.
Sub-series consists of meeting minutes of the Budget and Finance Committee. Files are arranged chronologically.
Meeting Minutes [textual record] – 11 Mar. 1938-20 Dec. 1938.
File consists of meeting minutes of the UJWF Budget Committee.
Meeting Minutes [textual record] – 1937-1938.
Meeting Minutes [textual record] – 1942-1943.
Meeting Minutes [textual record] – 20 July 1944-3 Nov. 1944.
Meeting Minutes [textual record] – 1945-1946.
Meeting Minutes [textual record] – 1948-1949.
Meeting Minutes [textual record] – 1950-1952.
Meeting Minutes and Reports [textual record] – 1951-1952.
File consists of meeting minutes and reports of the UJWF Budget Committee.


The Maker Movement is not oftentimes associated with World History, however, as many have shown, 'making' in K-12 can support content and curriculum across all disciplines. The World History students at my school recently embarked on a maker journey, related to their content area, and shared their maker stories through a video reflection. The goal in creating this unit was to create a new lens for opening, the content and related standards that needed to be covered, up to students. This unit was a collaboration between myself, the Library Media Specialist at my school, and our World History teacher.
Ultimately, we wanted to be sure that the unit understandings were "enduring" – that the deeper understanding of the content the students gained had enduring value beyond the classroom. We strove to create a framework that would ensure their learning would be meaningful and valuable outside of school. We accomplished this by offering them opportunities for authentic, discipline-based work, while at the same time allowing for a license for them to be creative. This unit pulls principles from project-based learning, inquiry-based learning, and maker education. We chose to connect this unit to the Renaissance because it is such a creative period in history and would speak to our students' creativity.
We provided multiple opportunities within the unit for students to demonstrate mastery of the unit learning goals through varied and frequent formative assessments. We made the decision from the start NOT to evaluate WHAT the students made, nor how they made it. We encouraged them to take risks and fail and fully encouraged and supported the iterative process. The video reflection was used as a tool to asssure that student learning became an enduring understanding, and it served as our summative assessment. Through our guidance, students created videos that were thoughtful and meaningful and that linked directly to our unit. Students were able to show, through their video reflections, how through making what they chose to make, they gained a deeper understanding of the Renaissance.
Day 1 kicked off with immersing the students in the Renaissance through group research and collaboration. We had a mini-lesson about using our school databases as resources and using Chromebooks and their own devices, students crafted paragraphs in a Google Doc that reflecting their basic understanding of the Renaissance. This served as our first formative assessment.
Day two kicked off with a mini lesson on crafting essential questions. Our World History teacher introduced our students to the work of Grant Wiggins and Jay McTighe. We spoke to students about what an essential question is and gave them guidance for crafting their own essential questions in relation to the Renaissance. We encouraged students to tap into their passions in creating their essential questions and choose areas of the Renaissance that would allow them to further explore their passions and interests. We explained to them that their essential question would drive their maker journey.
On day three, we had a group discussion about the challenges in creating essential questions. Many students expressed that they had to revise their questions several times before getting them to be just right. This opened up a discussion on the importance of having a growth mindset. We empowered them to take risks and chances in this unit and explained the process and strategies of the iterative process. We reminded them that their classroom was a judge-free zone and that they should feel free to explore whatever speaks to them. The creation of their essential questions served as another formative assessment.
From here, students began collaborating with their groups on choosing what it was they wanted to make to help them demonstrate deeper learning about their essential question, and therefore an enduring understanding of the Renaissance. We spoke to them about connecting what they decide to make to their passions and how this relevancy is what was going to make what they learned to about the Renaissance have value and meaning beyond just the classroom or this unit, a true enduring understanding. Through their essential questions, many students chose to compare elements of the Renaissance to things in the modern world, helping them to uncover that much more relevancy.
Students then began brainstorming, designing, and planning the creation of their final authentic products. They were encouraged by us to be open-minded, follow their passions, to be creative and to have fun. Students were captured and enthusiastic about being able to take control of their learning and to create and discover things that had meaning to them, especially in regards to a topic that felt often does not have relevancy to them. The things the students decided to make and do were nothing short of amazing.
Please view and comment on our student #makergrams here.
Laura Fleming has been a classroom teacher and media specialist in grades K-8 and currently is a Library Media Specialist for grades 9-12. She is a well-known writer, speaker and consultant on next-generation teaching methods and tools, and the author of the best-selling Worlds of Learning: Best Practices for Establishing a Makerspace for Your School.


High 5 Games is pleased to announce the addition of Lorin Jameson to its executive team as Vice President of Technology. Mr. Jameson arrives at H5G with an impressive and extensive background in management, production, and technology, having most recently served as Sony Online Entertainment's Head of Studio and Executive Director of Development in Austin, Texas.
After receiving his BS in Physics from the University of Washington, Mr. Jameson analyzed novel fusion systems under the guidance of renowned physicist Robert Bussard. He soon transitioned into the gaming industry, where he has spent upwards of the last 20 years. Starting at Kesmai, an early developer of online games, he worked on the pioneering Air Warrior, an early MMO that was one of the first 3D online games ever created. Mr. Jameson eventually formed his own company, Lodestone Games, where he developed games and technology for companies like Sony, EA, and Turbine. During his almost eight years at Sony Online Entertainment, Mr. Jameson oversaw the development and business strategy for the MMOs DC Universe Online and Star Wars Galaxies.
At High 5 Games, Mr. Jameson will oversee the engineering, QA, and game development divisions.
Developing for the land-based, online, social, and mobile markets, High 5 Games has created hundreds of games that are played on six continents and in more than 150 countries. Founded in 1995 with offices in New York and New Jersey, H5G is responsible for many of the casino industry's most successful video-reel slot machine games. The company's social product High 5 Casino is one of the best-performing casinos on Facebook, with more than 1.5 million active players and approximately 500,000 daily active users.


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