Yes, cleaning is expected. You are required to leave the cottage in the same condition as when you arrived. Cleaning services are expensive due to the water access and may be available with advance notice for $240.
Yes, we provide a 14 foot aluminum boat with a 15hp motor for your use during your stay. If you desire a second boat, similar boats are available from Dennes Marine for $150 per day.
Can I use the boat to get back to my car?
Yes, you may use the boat provided to return to your car during your stay.
How much is the water Taxi?
Is there a road to get to the Cottage?
No. The cottage is accessed by water only. We are on mainland however there is no road available.
Is the cottage available for weekly rentals?
The cottage is available for select weekly rentals from May – October. We frequently have 4-5 night rentals available during the week (i.e. Sunday to Friday). Please see our availability Calendar for more information.
Are there laundry facilities on site or in town?
There is a clothes line outside for fresh country drying.
Do I need a license to drive the boat?
Yes. You will need to a Pleasure Craft Operator Card.
In order to obtain the card, you need to pass a multiple choice test. Their are weveral websites where you can take the test.
If you do not pass the first time, many of these websites allow you to take the test again for free. Most also include an online course. The cost is between $34.00-$60.00.
What if I do not want to drive a boat?
Water taxi service is available for you from Denne's Marine. There is another Water Taxi service however we cannot recommend it at this time.
I have my own boat, can I bring it?
Yes. You can bring a "cottage lake" type boat. You will be hard pressed to launch a cabin cruiser or race boat on the lake. There are several boat ramps including one at Dennes Marine and docking is available at the cottage.
Can we drink the lake water or tap water?
The water has been tested and is safe to drink. The water does have a slight colouration remaining after filtration. The water is pumped from the lake and is processed through 5 filter stages including Sediment, Tannin, Iron, Bacteria as well as UV light system. You may still prefer to bring bottled water.
Kahshe Lake Cottage is surrounded by Crown Land to the South and East. There is a family cottage to the west and a third in the small bay. We are situated on 2 Acres with only a few cottages in the area.
Should I bring my own sheets and towels?
You need to bring your own towels, we supply sheets and blankets for your use indoors during your stay. You will need to bring towels for showering or outdoor use.
Is there a shallow entry point to the lake?
Yes, there is a shallow entry as well as deep entry from the dock.
Please contact us. Dogs maybe allowed, however due to the number of people with Allergies these days, we limit the frequency and type. Dogs are not allowed on the furniture or beds please.
Can I get directions to the cottage?
What does "water access cottage" mean?
For me, it means true nature, safety and peace. In practical terms it means that you do not drive to the cottage. You park your car at Denne's Marine, where your Water Taxi awaits. The cottage is a short boat ride away (Approx. 15 minutes).
The good part is that the water access cottage areas are less populated and allow more privacy.
What direction does the cottage face?
The Cottage faces North West. Perfect for an evening Sunset.
Can I hike to the Trans Canada Trail?
Yes. It is approximately 3 km of hiking from the cottage to reach the Trans Canada Trail.
What is the nearest town and how far is it?
The nearest town is Gravenhurst. It's approximately a 10 min drive from Denne's where your car will be parked.
Yes, there's great swimming accessible from the shallow entry beach, or the dock.
From what I hear, the fishing is great. The following fish have been caught recently: Large & Small Mouth Bass, Sunfish, Perch, Pickerel and Northern Pike.
Kahshe Lake is in the District of Muskoka in Ontario, Canada. The lake can be accessed from Highway 11 about 15 km north of the Severn River and 10 km south of Gravenhurst by either the North Kahshe Lake Road or the South Kahshe Lake Road. Our cottage is accessable via North Kahshe Lake Road.
Where did the name "Kahshe" come from?
The original inhabitants of the area called it Kahsheshebogamog. There is a variety of opinions on what that means. One version says that it means lake of many islands. This name was shortened to accommodate the maps — it was just too long! Some say it means Lake Of Healing Waters and others say it means Lake of Many Bays.
Kahshe Lake is the fourth largest lake in Muskoka. The surface area is 7.51 square kilometers. It has a volume of 36 million cubic meters. The watershed area covers 32.6 square kilometers. It has a mean depth of 4.9 meters and a maximum depth of 21.3 meters.


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My Worst Travel Moments of 2020
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I thought that 2016 was bad. This was worse — SO many times worse, universally worse. The year that will be written about forever as the dumpster fire of the early 21st century.
We're going to look back at 2020 as the year when everything fell apart. But even in the year that brought us COVID, I'm going to remember a lot of the more lighthearted travel moments.
Here are my worst travel moments of 2020!
Everything that COVID hath wrought.
You can't begin to talk about the worst travel experiences of 2020 without having a big section for COVID.
First off — I am so grateful that none of my family or friends have died of COVID. Not everyone can say that, and my heart is with everyone who has lost a loved one.
At the same time, I've watched several of my friends battle COVID. One friend was hospitalized. A few friends have become COVID long-haulers, struggling with frightening symptoms months later.
There was the endless worry. Worrying about my parents. Worrying about my country.
And while money is nowhere near as important as people, it really sucked watching my business of 10 years shrivel down to nothing, my income down by 90%. Most travel professionals in the world saw their incomes nose-dive as well. A lot of travel businesses closed for good this year.
There were the missed trips. My long-awaited trip to Peru and Ecuador was cancelled. Some big, well-paying campaigns were cancelled (and will hopefully be rescheduled in 2021).
The postponed weddings. Four of them I had hoped to attend. (Two were supposed to be on the same day in different countries, so maaaaybe I can still make them work?)
Being banned from my boyfriend's country, and my boyfriend being banned from my country. Months and months passing before I got permission to return to the Czech Republic.
But the worst part has been not knowing what the future holds. It's a loss of innocence similar to post-9/11. Who knows what has changed forever?
I'm optimistic for what the next year holds, especially since the vaccines are finally here, but I know that travel won't be back to its usual levels for a long time. And that affects all of us who work in this industry.
Now — on to the lighter moments.
Erwin and the Bleaching Incident
I fell in love with our Mérida house from the moment I saw it online. It was a designer home, and though it was much pricier than other Mérida properties, I felt like it was worth it, especially since I would be splitting it with Charlie and our friend Klara.
And the house came with weekly cleaning from a local man named Erwin. He washed the sheets and towels each week, and he left pieces of solid detergent in the washer and all over the laundry room.
This solid detergent left white stains all over our clothes. Including on some designer pieces I had bought secondhand and were irreplaceable.
You can see a big bleach spot in this photo.
I showed him the spots. "Es bleach. Blanqueador."
He shook his head. "No es bleach."
What?! I showed him more pieces. "Es bleach." I pointed to the label on the detergent. "Mira. Bleach!!"
He shrugged.
As for the cleaning, he would wipe down half a table and leave the other half dirty, or would halfheartedly sweep one room and leave piles of dust around the house. The one time the house was actually cleaned was when he brought a woman to help him.
Two weeks before we left, Erwin told us he wouldn't be cleaning that week because he was on vacation. "That's fine!" we told him. The following week, for the last cleaning, he told us he wasn't cleaning this week. He gave no reason. We shrugged. It was fine.
But I did NOT expect our Airbnb host, a French woman, to write the first negative Airbnb review I've ever received, saying that we left the place dirty and it was so disrespectful of us to do that!!! CAN YOU BELIEVE THAT?!
I'm so glad that Airbnb gives you the option to respond to reviews. I responded in great detail about her cleaner not showing up for the last two weeks, as well as giving her a detailed review of why so much had been wrong with this rental (she had lied to us about the internet speed before we booked, the furniture was unsuitable for working, and she asked us to pay extra for utilities when we arrived, against Airbnb's rules). I ultimately recommended she hire a property manager, which would solve most of these problems.
Getting our clothes destroyed was awful. But receiving that review was even worse.
The Journey from Ferrara to Prague
Man, was this a mess! When the Czechs finally gave me permission to return, I was in Ferrara, Italy, staying with my friend Katie and her family. I booked a train journey from Ferrara to Venice to Vienna to Prague. I'd leave Ferrara early and get to Prague around midnight.
The first leg, from Ferrara to Venice, went fine. I grabbed what I had hoped to be my final-cappuccino-standing-at-the-bar and made my way to the platform for my connection to Vienna. At Venice Mestre station, you have to go to a basement hallway to move between platforms, then climb stairs to get to the platform.
"Vienna?" an employee asked me at the bottom of the stairs. "Si." He scanned my forehead with a thermometer and let me climb the stairs to the platform.
I waited for the train. But even when it was two minutes away, the sign on the platform remained blank, as were most of the platform signs in the station. And up on the platform, there were no screens listing all the trains and their platforms; you had to go downstairs to find those.
In short: my platform changed at the last minute, and I JUST barely missed it.
I went to the Trenitalia office and they booked me on the next train, several hours later, for free because the signs had been off. This train would get to Vienna at midnight. Charlie planned to drive to Vienna and pick me up; we'd have to cross the Czech border and overnight there for COVID reasons.
I spent hours killing time, once getting kicked out of an empty hotel lobby for COVID reasons ("Not a guest? You can't sit here!"), and when it was time for my train, I kept crossing back and forth between the platform and the downstairs just to make sure it wasn't changed again with two minutes to go.
Then with two minutes to go…it was CANCELLED ALTOGETHER. Come on!!! And the office refused to refund me because apparently the Austrians were at fault, not the Italians.
By that point, Charlie was halfway to Vienna. I ended up booking an overnight Flixbus from Venice to Brno in the eastern part of the Czech Republic, killed a few more hours, and eventually left on time. Charlie stayed overnight in Brno and picked me up at 7:00 AM — and we went back to the hotel to SLEEP.
Figures that I would face one final gauntlet before getting back to Prague!
Not Protesting in Person
When the Black Lives Matter protests began after George Floyd was killed in late May, I became active in the ways I knew best: I donated money. I used my platform to bring attention to the right news stories. I dove into antiracist literature, examined my own failures, and worked on undoing a lifetime of racist programming, a lifetime of benefiting from white supremacy.
But I did not protest on the street.
I wanted to be out there protesting in person with everyone else — SO badly — but I did not. At that time, I was living with my dad and seeing my mom often. Both are seniors and neither could afford to get COVID. They were both being very careful and I couldn't do anything that risked their health.
The other reason was that I was about to apply for a visa in the Czech Republic and would be rejected if I had a criminal record. Many protestors were arrested, a great many of them unjustly, even those protesting peacefully. I couldn't risk getting arrested right when I needed to secure my visa.
And so I stayed at home. Had I still been living in New York, I would have been protesting in the streets most days.
I know someday someone will ask me what it was like protesting in 2020, and I'll have to say, "I couldn't tell you. I couldn't risk getting arrested or getting my parents sick, so I stayed home."
It's worth mentioning that a study in Massachusetts later showed protestors only had a marginally elevated risk of contracting COVID, due in part to near-universal mask usage in an outdoors environment.
Driving down a Terrifying Road in Korčula
On our day of driving around Korčula, we wanted to visit the beach of Pupnatska Luka, a small bay on the southern edge of the island. So we called up Uncle Google, as the Czechs call him, and followed the path that he chose for us.
Korčula, like many Croatian islands, has very steep hills leading down to the coast. Which is why I freaked out when Google brought us to a road that was barely a road.
It was rocky, it was makeshift, and it sounded like it was going to tear the engine out from the bottom of the car. All at a precipitous angle.
We moved downhill at a super-slow speed as I yelped with every bump. Finally, we arrived on a paved road that turned into a parking lot.
There was another road down to the beach. It was perfectly paved.
UNCLE GOOGLE, WHAT WERE YOU THINKING?!
Ferry Mishaps in Croatia
Have you ever taken a ferry in Croatia? This year showed me how much Jadrolinija, Croatia's national ferry company, is a mess.
In a day that would take us from Brač to Korčula, we had three ferries planned: Sumartin on Brač to Makarska on the mainland, Ploče on the mainland to Trpanj on the Pelješac peninsula, and Orebič on Pelješac to Korčula. We had booked the tickets in advance. It was all carefully timed with an extra buffer for mishaps.
Well. Our first ferry was delayed by 90 minutes. Had we ordered tickets online? Yes. Did they email us to let us know? No, they did not!!
This would just BARELY give us enough time to get to Ploče. We gunned it as soon as we arrived, and after a stunning drive down the coast, we landed in Ploče just in time. The workers waved us onto the line of cars waiting for the ferry. We parked and got out to grab some food.
Then we passed a sign that read SPLIT. "We should probably double-check to make sure this isn't the boat to Split," I told Charlie.
We went up to the men guiding the cars in. No, this was not the ferry to Split, the men said. But the ferry to Trpanj, the one for which we had a ticket, was full. They had directed us into the line for the NEXT ferry to Trpanj, which was in four hours!! WHY had they not told us that? How is it that you can have a ticket for a ferry and they won't let you on?!
Under ordinary circumstances, we would have been stuck. But luckily we were on the edge of the pier. I carefully, carefully guided Charlie out of our parking spot, keeping him from driving into the ocean, and we were out of there.
That ferry wasn't totally necessary — you can drive to Orebić; it just requires you to drive the long way, through Bosnia. (This effectively reset my time in the EU at zero days, which we didn't realize until later. I needed at least 14 consecutive days in the EU before Italy would let me in.)
We drove through Peljesač, passing oyster traps and wineries, driving through some of the most gorgeous mountain scenery we had seen yet. And getting on the ferry to Korčula was so simple and easy, we couldn't believe it!
Straining my Eyes in Croatia
I had been shooting lots of photos in Grožnjan, and afterward, my eyes felt weird. It was like they were each focusing differently, which lead to headaches and nausea.
After a few days, things hadn't improved, and WebMD had convinced me I had a variety of deadly neurological illnesses and THIS WAS THE FIRST SIGN!!
Eventually I went to see an ophthalmologist in Venice. He told me that my eyes were fine — I had just strained them. And I would probably be better off shooting while looking at the back of my camera rather than my viewfinder. He was right; my eyes went back to normal 48 hours later.
And as a reminder that healthcare in Europe is SANE — even as a visitor, I dropped into a random doctor's office and paid just 100 euros, whereas the same situation in the US could be several times that.
The Surtida Incident
On the way to Campeche, we made a stop in Hecelchakán Municipality. Why? Cochinita. This little town serves up some of the best cochinita pibil, or slow-roasted pork, and it was usually gone by midday.
We sped down the highway so we could make it on time. We found the cochinita stand, got into the right line, and ordered some tacos and tortas.
"Surtida?" the server asked.
"Si," we said, not knowing what that meant, but you say "si" when a local offers you something, don't you?
We went to eat our food, and the cochinita was delicious. But…there was something else. Something dark.
Turns out "surtida" means "assorted" — we had accidentally ordered a pile of assorted pig parts on top of our cochinita. Definitely liver. Likely intestines or ears or curly tails.
I wouldn't recommend it!
The Rainstorm From Hell
Croatia's Dalmatian Coast is one of the most beautiful places in the world to be in the summer. One reason? Nearly perfect weather.
Note that I said "nearly."
Dalmatia has gorgeous sun-drenched days, but it gets one MEGA rainstorm every summer, and it took place in early August.
Charlie and I were staying in an apartment in Pelješac and weren't feeling that hungry for dinner — so we planned to eat a little bit of the muesli we had bought earlier. Then we saw a trail of ants leading right into said muesli. Ugh. Grocery stores were closed and we had to go out.
It had just started raining, but as soon as we hit the next town, it began pelting down like mad. One of the most intense rainstorms I had ever seen.
We ran down the 80 meters or so into the closest restaurant, getting ourselves completely soaked through. But here we were in an actual restaurant!
The waitress looked surprised when we burst in. "Reservation only," she said. Ah well. Another rain-drenched run back to the car.
By that point, the rain was coming down so hard that we decided to pull over and wait it out. Peljesač is home to some of the most beautiful driving in Croatia, but what makes it beautiful on sunny days is what makes it terrifying in the rain — small, curvy roads edging alongside mountains, dangling above the precipice.
We waited out — and it did not get better. We were going to be here all night.
We drove down a steep road into another town, nearly drove into the ocean at one point, and ended up making one more run from the parking lot to a restaurant.
And they welcomed us in with thick towels and steaming bowls of tomato soup. And candles, once the power went out a few minutes later.
As we drove back to our accommodation, we were taken aback by the huge chunks of mountain that had fallen into the highway while we were eating our soup.
I'm glad it it only rains like that once a year!
Flying in the time of COVID
I laugh a bit when I look back at the precautions I took when flying home from Mexico City to Boston on April 9. I covered my hair with a tank top; it looked like a do-rag. And I was obsessive about washing: I had read all these guidelines that said you couldn't even TOUCH your mask or your face without washing your hands, and if you replaced your mask, you had to wash your FACE before replacing it.
So I was in the airport bathroom washing my hands, taking my mask off, washing my face, drying my face, washing my hands again, putting a fresh mask on, and washing my hands one last time. At the time, that's what we were told we had to do, but it was a bit overkill!
Even so, those two flights only had a few passengers on board, so it was easy to distance.
Flying from New York to Belgrade on June 26 was different. The flight was nearly full and I spent the whole nine-hour journey worrying about COVID exposure. I ate a ton of McDonald's before the flight so I didn't have to eat; twice I stuck my water bottle's straw behind my mask for a few sips of water, and that was it.
It was nerve-wracking — but then I was in Serbia. A long, curvy overland journey through seven countries took me back to Prague, and I haven't been on a plane since.
Deciding Whether to Stay or Go in Mexico City
But the absolute worst time this year was what we faced in Mexico City. We arrived on March 15, at a time when Mexico just began canceling crowded events, and were originally supposed to stay for 10 days. Shortly after we arrived, two of our booked events were canceled (a Lucha Libre match and a party boat at Xochimilco), as were our onward flights at the end of March (me to Peru, Charlie to the UK).
Our dilemma: Do we stay or do we go?
Looking back, it seems obvious — just go home and lie low! But in late March, things were chaotic. At that time, much of Europe was under lockdown and had closed their borders to Americans; in the United States, COVID was raging in the two places I would have gone: New York and Boston. And flying was seen as one of the most dangerous things you could do. We didn't even have masks yet.
Staying in Mexico seemed much safer by comparison, at least at that time. Some people had pointed out that all the major COVID outbreaks were in colder climates. Maybe Mexico would stay safe. The first Mexican died of COVID on March 19, and the national media kept talking about his preexisting conditions, as if to rationalize that perhaps that was why he had died.
Plus, as a couple holding different passports — me, an American, and Charlie, a UK citizen and Czech permanent resident — we had no idea if we would end up separated for months.
But what happened if things in Mexico got worse? This is a nation where a lot of people work on the street and would be vulnerable to COVID as well as exponentially affected by a shutdown. What if the disease spread more quickly here? What if it led to violence or political unrest? Could Mexico become the WORST place to be in a pandemic?
We could fly into a pandemic hot zone, separating for an indefinite amount of time — or stay in place as the pandemic worsened and be unable to leave. We began evaluating everything from food delivery options to private hospital access to how to evacuate.
And then Mexico City hotels began to close, and lots of buildings wouldn't allow Airbnb guests in. If we had to leave our accommodation, there was no guarantee we could stay anywhere.
It was the most difficult decision of my life — and I had no idea whether this decision would result in illness or even death.
Finally, after extending our apartment stay a few times, we decided to leave — and as soon as we booked our flights, they were cancelled. In the end, we flew out in April and Charlie got one of the last flights from Mexico City to Europe.
The Hvar Boat Rental Incident
Well, let's end things on a funny note. When in Hvar, we decided to rent a boat for the day and explore the Pakleni Islands, an archipelago southeast of the island. You can rent a boat in Croatia without a license, and we figured it would be easy.
Well. We hadn't planned on it being so hard to start the motor. We took a break to explore one of the coves — then when it was time to leave, we pulled up the anchor but couldn't get the motor started. So we crashed into a boat filled with a multi-generational family blasting music and relaxing.
Next, we bashed into the rocks and Charlie fell on the rocks, cut his foot, and scraped his right side up (he's still bearing scars months later).
We decided to head to a mostly empty cove — there's only one boat in it. Italians. We ended up parking out boat near them. Then we realized that they were alone because THEY WERE COMPLETELY NAKED and suddenly WE WERE THE WEIRDOS SIDLING UP TO THE NUDISTS!
Later, we stopped for lunch in a village and there are no spots to tie up on shore, so Charlie dropped me off with the cameras, parked in the middle of the water, and swam to shore. On the way back, he swam back, but by this point the dock was even more crowded — so he backed the boat up to the dock and THWACK THWACK THWACK! Hit three boats in a row.
By that point important cords had been pulled out of the boat and it wouldn't start. Charlie called the boat people and apologetically told them what happened. (They couldn't have been nicer about it, and we got a ride back with a local.)
It goes to show — some people are not boat people. Just because you can rent one in Croatia, it doesn't mean you should!
What were your worst travel (or non-travel) moments of the year?
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6 thoughts on "My Worst Travel Moments of 2020"
Katherine Brennan
Have you been able to visit France from one of the EU countries with your US passport during Covid?
Adventurous Kate
I personally did not but I think they may have had the same rule as Italy, allowing anyone who had spent the previous 14 days in the EU.
The vast majority of my trips were cancelled, starting with my return to East Asia in April (Seoul, Taipei, Bangkok); then Bulgaria; then the Caucasus – Georgia left it *really* late, saying they'd open to tourists again on July 1st, then that changed to a select group on August 1st…I don't know if it ever materialised, but Brits were never on the list; Tokyo at the end of October was cancelled as Japan re-banned Brits in late August/early September; Lufthansa have cancelled my flights for Feb 2021 to Slovenia, and Finnair have changed the dates on my rebooked East Asia flights, which mean I now can't go…..so…..August 2021 perhaps, if I've had the vaccine! Who knows.
Apart from that, I went on two trips internationally: Tunisia was a DISASTER. I ended up spending a total of 10 hours on a train to El Djem and not even seeing it. In hindsight I'd go back but book day tours and not rely on the country's infrastructure; Bologna and San Marino in late July was wonderful; domestically, I took a wonderful trip to Edinburgh in late July/early August too.
Fingers crossed 2021 will be better for travel!
Tom!! So glad to see you here!!! I hope you've been well. And man, that sucks having to cancel so much awesome travel! I'm sure you'll be back at it by summer. Sorry to hear Tunisia was a disaster too. I'll definitely hit you up before I go to find out what to avoid.
Becky Strom
Dear Kate, Your stories made me say a word of prayer for each one of them. You are a lot braver than me. I've traveled twice by myself, driving around Scotland and the Camino but that's about it. I do have funny stories from then but nothing recent since it was all canceled. I love your posts and your courage. Becky
OMG, that was an extremely stressful read, LOL
At age 26, I quit my job to travel the world alone. I spent six fantastic months in Southeast Asia and turned my travel blog into a full-time business. Nine years later, I'm still traveling -- 83 countries and 7 continents! My goal is to show YOU how you can travel the world on your own -- easily, safely, and adventurously. Read more here.
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Successfully defended restaurant owner sued by developer/contractor in Gwinnett County for breach of contract to construct restaurant.
Successfully defended health and fitness business owner sued by former shareholder and employee in Fulton County for proceeds of business.
Successfully defended builder sued in Gwinnett County by insurance company which sought to avoid providing insurance coverage for claims brought by owners of neighboring properties.
Multiple multi-million dollar judgments in favor of banks in commercial lending disputes with borrowers and guarantors in venues located throughout Georgia.
Enforced non-solicitation covenant against former employee who attempted to compete in violation of restrictive covenants and recovered financial settlement from employee.


Educational Qualification: M. Sc., Ph. D.
Awards: Young Scientist Award 1995 by M. P. Council of Science & Technology.
Area of Interest Nanophotonics (Photonic crystals and devices), Optical soliotons (propagation and devices), Waveguide devices, Optical computing, Fibre optics, Integrated optics.
Chairman, International Students & Research Cell since 30.10.13.
Registrar (I/c) from 30.7.15 to 23.6.15.
Controller of examinations (i/c) since 16.1.16.
Sarang Medhekar (PI) and P. K. Barhai (Co-PI) received a research Grant of Rs. 3.10 Lakhs from UGC on 1 July 2003 for the project titled "Theoretical Investigation of Induced Nonlinear Optical Fiber Waveguides and Devices" (Project Reference No.: 10-25 /2003 (SR); Duration 3.5 years; Status: Completed.
Sarang Medhekar (PI) and P. K. Barhai (Co-PI) received a research Grant of Rs. 8.87 Lakhs from BRNS-DAE on 16 Feb. 2004 for the project titled "Investigation of the effects of higher order nonlinearities on optical pulse propagation in semiconductor doped glass fibers and waveguides" (Project Reference No.: 2003/34/19/BRNS/1951; Duration 4 years; Status: Completed.
Sarang Medhekar (PI) received a research Grant of Rs. 24.68 Lakhs from DST on 10.2.2009 for the project titled "Modeling and Analysis of Mach-Zhender Interferometer based Nonlinear Waveguide Devices for All-Optical Switching and Logic Gates" (Project Reference No.: SR/S2/LOP-27/2007; Duration 3 years; Status: Completed.
Sarang Medhekar (PI) received a research Grant of Rs. 8.278 Lakhs from UGC on 30.12.2008 for the project titled "Investigation of Optical Beam Propagation in Nonlinear Media: Spatial Soliton Formation and Their Interaction for All-Optical Devices" (Project Reference No.: 34-24/2008 (SR); Duration 3 years; Status: Completed.
Mechanical load stabilizer with load dependent stepless gear ratio variation system, Inventor: S. Medhekar, Patent no. 223097, Year 2008.
Extraction of one beam from a mixture of two coaxially co-propagating mutually incoherent beams of same frequency, Extraction of Data Bits loaded on one coherent beam mixed with the Data Bits loaded on another coherent beam of same frequency and Coherence Division Multiplexing (CDM), Inventor: S. Medhekar and Punya Prasanna Paltani, Patent no. 261064, Year 2014.
Man Mohan Gupta, Sarang Medhekar, All-optical NOT and AND gates using counter propagating beams innonlinear Mach–Zehnder interferometer made of photonic crystal waveguides, Optik-International Journal for Light and Electron Optics 127 (2016) 1221–1228.
Man Mohan Gupta and S Medhekar, Switching Behavior of Nonlinear Mach-Zehnder Interferometer Based on Photonic Crystal Geometry, Pramana Vol. 82, No. 6, 2014, pp. 1061–1074.
R. K. Choubey S. Medhekar, R. Kumar S. Mukherjee Sunil Kuma, Study of nonlinear optical properties of organic dye by Z-scan technique using He–Ne laser, J Mater Sci: Mater Electron, DOI 10.1007/s10854-014-1743-3, Jan 2014.
Shraddha Prasad, Ram Krishna Sarkar and Sarang Medhekar, Coupled tapering/uptapering of soliton pairs in nonlinear media, Optik-International Journal for Light and Electron Optics., 124 (2013) 6661– 6665, http:// dx.doi.org/ 10.1016/ j.ijleo.2013.05.108.
Arpita Srivastava Sarang Medhekar, Effect of change in core width and core refractive index on the switching behaviour of a nonlinear Mach–Zehnder interferometer, Optical Engineering 51(9), 094601 (September 2012).
Arpita Srivastava and S. Medhekar, Switching Behavior of a Nonlinear Mach-Zehnder Interferometer with Exponentially Saturable Nonlinearity, Optical Engineering , Vol. 51, Pages 074604-1 to 074604-4, 2012.
D. B. Lata, A. Mishra and S. Medhekar, Effect of hydrogen and LPG addition on the efficiency and emissions of a dual fuel diesel engine, International Journal of Hydrogen Energy Vol. 37, Pages 6084–6096, 2012.
Arpita Srivastava, Man Mohan Gupta, S. Medhekar, Signal amplification based on the local nonlinear Mach–Zehnder interferometer, Optics & Laser Technology, Vol. 44, 492–496, 2011.
D. B. Lata, A. Mishra and S. Medhekar, Investigations on the combustion parameters of a dual fuel diesel engine with hydrogen and LPG as secondary fuels, International Journal of Hydrogen Energy Vol. 36, 13808–13819, 2011.
Shraddha Prasad, Ram Krishna Sarkar, Arpita Srivastava and S. Medhekar, Coupled Propagation in Electromagnetically Induced Transparent Medium; Thirring Type Soliton Pairs and Breather Pairs, Journal of Electromagnetic Waves and Application, Vol. 25, 923–933, 2011.
Arpita Srivastava, S. Medhekar, Switching behavior of a nonlinear Mach–Zehnder interferometer: Saturating nonlinearity, Optics & Laser Technology, Vol. 43, Pages 1208 to 1211, 2011.
Arpita Srivastava, Ram Krishna Sarkar, Shraddha Prasad and S. Medhekar, Coupled tapered / uptapered optical beams, Optik-International Journal for Light and Electron Optics., 122 (2011) 2039– 2043.
Arpita Srivastava and S. Medhekar, Switching of One Beam by Another in a Kerr Type Nonlinear Mach-Zehnder Interferometer, Optics & Laser Technology, vol. 43, issue 1, pp. 29-35(2011).
Punya Prasanna Paltani and S. Medhekar, All-optical Circulator Based on Cross Phase Modulation in a Nonlinear Mach-Zehnder Interferometer, Optik-International Journal for Light and Electron Optics., Volume 122, Issue 5, March 2011, Pages 464-466.
Punya Prasanna Paltani and S. Medhekar, Optimally Stabilized Beam Pairs, Optik-International Journal for Light and Electron Optics., vol. 122, issue 1, pp. 70-75(2011).
Arpita Srivastava, Punya Prasanna Paltani and S. Medhekar, Switching Behaviour of a Nonlinear Mach-Zehnder Interferometer, Pramana, Vol.74 Number 4 (2010) p. 575-590.
Ram Krishna Sarkar and S. Medhekar, Mutual-focusing of two co-propagating beams and formation of trapped spatial breather pair in saturable nonlinear media, Optik-International Journal for Light and Electron Optics., 121 (2010) p-339–346.
R. K. Sarkar and S Medhekar, Spatial soliton pairing of two cylindrical beams in saturable nonlinear media, Progress In Electromagnetics Research M, Vol. 9, 53-64, 2009.
S. Medhekar and Punya prasanna Paltani, All-Optical transistor using counter propagating beams in a Nonlinear Mach-Zehnder Interferometer, Fiber and Integrated Optics Vol. 28 Number 4 (2009) p. 268-274.
S. Medhekar and Punya prasanna Paltani, Novel All-Optical Switch using Nonlinear Mach-Zehnder Interferometer, Fiber and Integrated Optics Vol.28 Number 3 (2009) p. 229-236.
S. Medhekar, Ram Krishna Sarkar and Punya P. Paltani, Soliton Pairing of Two Coaxially Co-Propagating Mutually Incoherent 1-D Beams in Kerr Type Media, Optica Applicata, XXXVII, 243-259 (2007).
Ram Krishna Sarkar and S. Medhekar, Spatial Solitons of desired intensity and width and their Self-Tapering/Uptapering in Cubic Quintic Nonlinear Medium, Physica Scripta, Vol. 76, (2007) pp-683-688.
Punya P. Paltani and S. Medhekar, Synchronous Couplers Made of Symmetric and Asymmetric Slabs, Nonlinear Optics, Quantum Optics Vol. 36 , (2007) pp-129-145.
S Medhekar and Punya Prasanna Paltani, All-Optical Switching and Tenable Wavelength Filtering in Grating Assisted Directional Coupler, Nonlinear Optics, Quantum Optics Vol. 36 , (2007) pp-81-90.
S. Medhekar and Punya Prasanna Paltani, Proposal for an All-Optical Switch, IEEE Photonics Technology Letters Vol. 18, No. 15 Aug. (2006) pp-1579-1581.
S Medhekar and Ram Krishna Sarkar, Passive, 'Self-Trapped Family" All-Optical Half Adder using All-Optical X-OR and AND Gate, Czechoslovak J. Physics, Vol. 56, No. 4 (2006) pp-359-366.
S Medhekar and Ram Krishna Sarkar, All-optical bistable and astable multivibrators, Nonlinear Optics, Quantum Optics, vol. 35, Sept. 2006, pp-287-296.
S Medhekar, R. K. Sarkar and P. P. Paltani, Coupled Spatial-Soliton Pairs in Saturating Medium, Optics Letters vol. 31, No. 1 Jan. 2006, pp-77-79.
Ram Krishna Sarkar and S Medhekar, Propagation of Doughnut mode in Nonlinear Media, Nonlinear Optics, Quantum Optics Vol. 35, Sept. (2006) pp-275-286.
S.Konar, P.K.Barhai and S Medhekar, Displacement and Deflection of Optical Beams by Nonlinear Planer Waveguide, J. of Nonlinear Optical Physics & Materials, Vol. 12, No. 1, p.101-112 (2003) USA.
S Medhekar, M.S.Sodha and S.Konar, Optical Power filter: A new kind of passive nonlinear optical device, Optics Letters, Vol.20, No.4, p-305(1996).
S Medhekar, S. Konar and M.S.Sodha, Self tapering of elliptic beams in elliptic core nonlinear fibers, Optics Letters, Vol.20, No.21, p-2192 (1995).
S Medhekar, S.Konar and Rajkamal, Successive uptapering and stationary self trapped propagation of a laser beam in a saturating nonlinear medium, Lasers & Particle Beams, Vol.13, No.4, p-559 (1995).
S Medhekar, S.Konar and Rajkamal, Profile of radial inhomogeinity for stationary self trapped propagation of laser beams in a nonlinear absorbing/amplifying medium with arbitrary nonlinearity, IL NUOVO CIMENTO D, Vol.17, p-351,(1995).
S. Medhekar, S.Konar and Rajkamal, Self tapering and uptapering of a self guided laser beam in an absorption/gain medium with arbitrary nonlinearity, Pramana-Journal of physics, vol.44, No.3, p-249(March1995).
M.S.Sodha, S. Medhekar, S.Konar, A.Saxena and Rajkamal, Absorption/Amplification induced self tapering and uptapering of a laser beam in a saturable nonlinear medium: large nonlinearity, Optics Letters, Vol.19, No.15, p-1110(Aug.1st 1994).
S. Medhekar, Rajkamal and A.Saxena, Propagation of Gaussian laser beams in a nonlinear radially inhomogeneous absorbing medium with arbitrary nonlinearity, Ind. J. Pure & Appl. Phys.Vol.31, p-605-609(Sept.1993).
S. Medhekar, Maximum possible transverse velocity in special relativity, Physics Education, Vol.7, No.4, p-320-322(1991).
S. Medhekar et. al. "Self tapering/uptapering of self guided beams" National laser symposium held at Center for Advanced Technology, C.A.T., Indore, INDIA during Jan.29-Feb.1, 1994.
S. Medhekar et. al. "Highly sensitive optical power filters", Photonics-96, international conference on photonics and related areas held during 9-13 Dec.1996 at Indian Institute of Technology IIT, Chennai, INDIA.
Sarang Medhekar, S Konar, P.K.Barhai, "All-optical pulse width manipulation of stationary temporal soliton" Photonics-2002, International conference on photonics and related areas held in Dec.2002 at Tata Institute of Fundamental Research, Mumbai, INDIA.
Ram Krishna Sarkar, S. Medhekar, and Punya Prasanna Paltani, "Analysis of Cross focusing of Gaussian beams in Saturating Nonlinear medium", National Laser Symposium (NLS-4), , held in Dec.2004 at Bhabha Atomic Research Centre, Mumbai, INDIA.
S. Medhekar and Ram Krishna Sarkar, "All-optical passive Isolator", Photonics 2004, International conference on photonics and related areas held in Dec.2004 in Cochin, INDIA, pp-121.
S. Medhekar and Ram Krishna Sarkar, "Propagation of doughnut mode in various nonlinear media", Asia Pacific Microwave Conference, International conference held in Dec.2004 in New Delhi, INDIA..
Punya P. Paltani and S. Medhekar, "Study of Grating Assisted Directional Couplers" National Laser Symposium "NLS-5", 7-10 Dec. 2005 at Vallore Institute of Technology, Vallore, INDIA.
Ram Krishna Sarkar and S. Medhekar, "Soliton pairing in nonlinear media", Photonics-2006, 3-16 Dec 2006 at University of Hyderabad, INDIA. page-375.
Punya P. Paltani and S. Medhekar "Switching Behaviour of Nonlinear Refraction Based optical Switch". 'Photonics 2006' 3-16 Dec 2006 at University of Hyderabad, INDIA. page-137.
Punya P. Paltani and S. Medhekar, "Theoretical Investigation of Directional Couplers and Their Synchronization". 'CODEC-06', 18-20 Dec 2006 at University of Kolkata, INDIA. page-205.
S. Medhekar and Ram Krishna Sarkar, "Co-propagating beams in saturating nonlinear media", NASDEC (2)-06, 2-4 Nov. 2006 at Birla Institute of Technology, Mesra, INDIA page-141.
Punya P. Paltani and S. Medhekar, "Analysis of Nonlinear Refraction Using Split Step Method", NASDEC (2)-06, 2-4 Nov. 2006 at Birla Institute of Technology, Mesra, INDIA page-151.
S. Medhekar and Ram Krishna Sarkar, "Analysis of Trapped Spatial Breather Pair in Saturable Nonlinear Media", National Laser Symposium (NLS-6), 5-8 Dec. 2006 at Raja Raman Center for Advanced Technology, Indore, INDIA. page-70.
Punya P. Paltani and S. Medhekar "Solitonic and Nearly Solitonic Beam Pairs" National Laser Symposium (NLS-6), 5-8 Dec. 2006 at Raja Raman Center for Advanced Technology, Indore, INDIA, page-69.
Shraddha Prasad, Ram Krishna Sarkar, Arpita Srivastava and S. Medhekar "THIRRING TYPE BREATHER PAIRS AND SOLITONS", PHOTONICS 2010: 10th International Conference on Fiber Optics & Photonics, December 11-15, 2010, IIT Guwahati, India.
S. Medhekar, Arpita Srivastava and Punya Prasann Paltani "PULSE SWITCHING IN A NONLINEAR MACH-ZEHNDER INTERFEROMETER", PHOTONICS 2010: 10th International Conference on Fiber Optics & Photonics, December 11-15, 2010, IIT Guwahati, India.
Arpita Srivastava, Man Mohan Gupta and S. Medhekar "SIGNAL AMPLIFICATION BY USING A NONLINEAR MACH-ZEHNDER INTERFEROMETER", PHOTONICS 2010: 10th International Conference on Fiber Optics & Photonics, December 11-15, 2010, IIT Guwahati, India.
P.P.Paltani, S.Medhekar, C. Senel, F.O.Ilday "ACCURATE GAIN MODELING FOR Er/Yb DOPED FIBER AMPLIFIER"PHOTONICS 2010: 10th International Conference on Fiber Optics & Photonics, December 11-15, 2010, IIT Guwahati, India.
Arpita Srivastava, Man Mohan Gupta and S. Medhekar "Switching Behavior of a Nonlinear Mach-Zehnder Interferometer With Different Saturable Nonlinearities", Second International Conference on Trends in Optics and Photonics (IConTOP) December 7 - 9, 2011, Kolkata, India.
Man Mohan Gupta, Arpita Shrivastava and S. Medhekar "Switching Behavior of Photonic Crystal based Nonlinear Mach-Zehnder Interferometer", Second International Conference on Trends in Optics and Photonics (IConTOP) December 7 - 9, 2011, Kolkata, India.
Ram Krishna Sarkar, Shraddha Prasad and S. Medhekar "Spatial Soliton Pairing in Radially Inhomogeneous Nonlinear Media" Second International Conference on Trends in Optics and Photonics (IConTOP) December 7 - 9, 2011, Kolkata, India.
Investigation of Light Propagation through Photonic Crystals (PCs) for All Optical Devices.
Extracts of the paper entitled "All-Optical Passive Transistor" has appeared as a report entitled "Theorists propose an all-optical Transistor" in PHOTONICS SPECTRA of Laurin Publication (USA)., pp.106, May 2005.
Visiting Research Professor at University of Hartford CT, USA during 25th Dec. 2007 to 16th Jan. 2008 and 7th July 2008 to 12th Aug. 2008 for a collaborative research work to demonstrate the proof-of-concept (POC) feasibility of All-Optical Passive Transistor (AOPT) proposed by me with my Ph. D. student Mr. Ram Krishna Sarkar.
Recipient of OPTEL fellowship for Ph D research work in the area of Fibre Optics (19910-1994).


you might choose to use a pick.
you might choose a combination of both.
it's usually referred to as hybrid picking.
to keep in mind the physical limitations that you personally might have.
Listen to your body, listen to your hands.
If things feel too strenuous over time that might create some kind of injury.
You do want to pay special attention.
the first thing we're going to talk about, I've seen a marriott of styles.
I'm going to offer you some suggestions, hopefully you'll find them helpful.
front door to your house with a key.
And you would sort of choke up on the key and hold most of the key in your hand.
And it would be more of twisting movement.
guide, you shouldn't wind up with any injuries.
more of, sort of a twisting.
area, or even your fingers.
choose any number of picks that are out there, that are available.
I choose some pretty heavy picks.
and they're actually made of, I think this is a bone of some kind.
you on guitar, whether you're playing acoustic or electric.
by using open strings and grasping the pick, choking up on it.
I'm going to do what's called the downstroke, typical downstroke is.
[SOUND] Now, I'm playing the sixth string which is the E string.
backwards from six to one.
So you can try some downstrokes like this.
And then in reverse order or in, from one to six now.
Now those are all downstrokes.
grab yourself a little metronome here.
And we're going to switch that on and we're going to do downstrokes.
beats per minute and then I'll going to do downstrokes for every click.
get to a higher speed and you're much more comfortable doing that.
really important to learn is what's called alternate picking.
So that means that it's a combination of a downstroke and an upstroke.
it's exact the opposite of a downstroke, and it sounds like this.
And I'm going to do it in time with the metronome too, so here we go.
So those are our upstrokes.
Now we're going to actually put them together to create the ultimate picking.
one up, and that's called ultimate picking.
So here we go alternate picking two strokes for each string.
[SOUND] Now we're going to keep our metronome going.
And we're actually going to do three notes per string.
we're going to go up, down, up, down as we switch to the other string.
[SOUND] So here we go.
Now we're going to do alternate picking, four notes per string.
We're going to speed up a little.
[SOUND] I'm actually going to use this.
Let's speed up a lot here.
just inch it up everyday to where you can actually handle faster tempos.
you're playing the notes at the slowest speeds.
And so eventually you can get to higher tempos and practice.
And maybe, say this is four notes string.


On Saturday 29th June 2019 Manic Street Preachers return to Cardiff Castle to play a very special hometown show celebrating their 1998 album 'This Is My Truth Tell Me Yours'. The band have previously announced a 20th Year Collectors' Edition of their fifth album – released 7th December, and a UK tour alongside this gig will round off the celebrations of their biggest album to date. This year they released their 13th album 'Resistance Is Futile' which reached No. 2 in the charts and played a huge arena tour. The Cardiff show, which will also feature hits and rarities from the bands extensive back catalogue, will have very special guests Sunflower Bean.
Tickets go on sale Friday 30th November – details below.


text:
CSocD Addresses Inequality of Vulnerable Populations
UN Photo/Lily Solmssen
The Commission for Social Development underscored the need to protect people from poverty, natural disasters and conflict and to focus on helping vulnerable groups to achieve the 2030 Agenda.
The Commission forwarded four draft resolutions to ECOSOC, including a draft resolution on the Commission's future organization and methods of work that agrees CSocD will consider a single priority theme each year.
The 2019 priority theme will be 'Addressing inequalities and challenges to social inclusion through fiscal, wage and social protection policies'.
30 January 2018: The 56th session of the Commission for Social Development (CSocD 56) called for efforts to accelerate inclusive and equitable economic growth and sustainable development to ensure that no one is left behind. It also supported a focus on helping vulnerable groups to achieve the 2030 Agenda for Sustainable Development. The Commission agreed on four draft resolutions, which will be forwarded to the UN Economic and Social Council (ECOSOC).
CSocD 56 convened from 29 January-7 February 2018, at UN Headquarters in New York, US. The Commission focused on the theme, 'Strategies for eradicating poverty to achieve sustainable development for all' and addressed both the drivers of poverty and recommendations to tackle poverty.
In opening remarks, UN Deputy Secretary-General Amina Mohammed welcomed achievements in reducing extreme poverty, providing access to health care and education and promoting the empowerment of women, youth, indigenous peoples, persons with disabilities and older persons. She cautioned, however, that progress on extreme poverty remains uneven "across regions, within countries and between various social groups." She underscored the need to address such inequality and unemployment and underemployment among the world's youth.
On poverty, the Commission discussed the role of strategies for poverty eradication in achieving sustainable development for all. Egypt for the Group of 77 and China (G-77/China) stressed that eradication of poverty in all its forms and dimensions "remains the greatest global challenge and an indispensable requirement for sustainable development." Equatorial Guinea for the African Group said 390 million Africans remain "mired in extreme poverty," despite commitments to eradicate poverty. Participants recognized the role of natural disasters, conflicts, civil unrest and economic slow-downs in driving poverty.
On social protection, many supported both universal health care (UHC) and social services for all. Mohammed said 45% of the people around the world who need social protection have access to only one benefit. She called for social policies and protection that ensure everyone shares the benefits of economic growth and globalization.
Liu Zhenmin, UN Under-Secretary-General for Economic and Social Affairs, observed that many people remain at risk of falling back into poverty if impacted by a disaster, illness, job loss or lack of social protection. He recommended developing a comprehensive and integrated socioeconomic policy framework. A representative from Malawi shared his country's cash transfer programme and holistic approach to implementing the SDGs.
On vulnerable populations, participants advocated for prioritizing the rights of older persons, youth, rural people and others in special situations. The International Federation of Associations of the Elderly said elderly people are particularly vulnerable to the consequences of disasters and impacts from conflicts and wars, and recommended managing older populations' post-traumatic stress from such crises. The International Relations Students' Association of McGill University, Canada, the only student‑run group that has consultative status with ECOSOC, called for taking youth voices into account in decisions on environmental change, energy, food security and migration.
Many participants echoed this call for the participation of youth in decision-making, stressing that youth can help to advance the 2030 Agenda and play a role in improving the use of science, technology and innovation (STI) and increasing transparency. Others highlighted: the importance of investments in early childhood education; the role of risk management and insurance in building resilience, especially in the context of climate change and natural disasters; and the potential of access to information and communications technology (ICT) in increasing the independence of persons with disabilities or older persons with mobility challenges.
On UN reform, Mohammed observed that the Commission can support the UN Secretary-General's current efforts to reposition the UN development system to deliver on the 2030 Agenda. She said the Commission's resolution on its methods of work can support these efforts, and emphasized the Commission's continued role as a space for policy debate and exchange of experiences.
CSocD 56 agreed on a draft resolution on the Commission's future organization and methods of work. By the text, governments decide that the Commission will focus on a single priority theme at each future session, leading to an action-oriented resolution with recommendations to the UN Department of Economic and Social Affairs (DESA). The resolution proposes the 2019 priority theme of 'Addressing inequalities and challenges to social inclusion through fiscal, wage and social protection policies.'
The resolution titled, 'Third review and appraisal of the Madrid International Plan of Action on Ageing, 2002′ (document E/CN.5/2018/L.3), recognizes the contribution of older persons to implementing the SDGs, and encourages States to consider the health, care and well-being of older persons in their national SDG implementation. The Commission further agreed on resolutions on: 'Social dimensions of the New Partnership for Africa's Development' (document E/CN.5/2018/L.4); and 'Strategies for eradicating poverty to achieve sustainable development for all.'
Four high-level panel discussions convened throughout CSocD 56, including a high-level panel that discussed evidence-based mainstreaming of disability in the 2030 Agenda. Another high-level panel focused on the UN Secretary-General's report on the Madrid review on aging. The report identifies trends and obstacles to implementation of the Plan around the world. Other panel discussions addressed sustainable and resilient societies, including the role of technology for social need and social good, and of innovative ICT in the 2030 Agenda. The Commission also discussed a report on poverty eradication, reviewing progress on and discussing country strategies to implement SDG 1 (no poverty).
ECOSOC President Marie Chatardová noted that the Commission's discussions on eradicating poverty will contribute to the 2018 session of the UN High-level Political Forum on Sustainable Development (HLPF). [Meeting Website] [UN Press Release on CSocD Opening] [Deputy Secretary-General Opening Remarks] [UN Meeting Coverage, 29 January] [UN Meeting Coverage, 30 January] [UN Meeting Coverage, 31 January] [UN Meeting Coverage, 1 February] [UN Meeting Coverage, 5 February] [UN Meeting Coverage, 7 February] [DESA Press Release, 8 February] [E/CN.5/2018/3] [E/CN.5/2018/2] [E/CN.5/2018/4] [A/73/61-E/2018/4] [E/CN/5/2018/5]
56th Session of the Commission for Social Development
1. No Poverty10. Reduced Inequalities17. Partnerships for the Goals
Governance, Sustainable Development, Poverty Eradication, Human Rights & Indigenous Peoples, Disasters & Humanitarian Relief, Human Settlements & Population, Science, Economics & Investment, International Negotiations
Means of Implementation, Technology / Transfer
Africa, Asia, Near East, Northern America, Central Africa, North Africa, Southern Africa, West Africa, Eastern Asia
SDG Knowledge Weekly: Local Collaboration, Innovative Policies and Partnerships
26 February 2018 | Adam Fishman, SDG Knowledge Hub
SDG Knowledge Weekly: Local Collaboration, Innovat...
Nigeria SDG 1 Initiatives in Focus on CSocD Sidelines
8 February 2018 | Nathalie Risse, Ph.D., SDG Knowledge Hub
Nigeria SDG 1 Initiatives in Focus on CSocD Sideli...


text:
Xbox One outsells PS4 in April as Mortal Kombat X tops game sales
By Colin Campbell@ColinCampbellx May 14, 2015, 7:30pm EDT
Source NPD | Via VentureBeat | Image Shutterstock
Share All sharing options for: Xbox One outsells PS4 in April as Mortal Kombat X tops game sales
Xbox One outsold PlayStation 4 in the U.S. during April, according to NPD's monthly industry report on game and console sales. The top-selling packaged game was Mortal Kombat X.
As is tradition, the two leading console makers released statements about their respective performances. NPD does not release actual sales numbers to the public, selling those to interested parties.
"As the best-selling console in the U.S. in April, fans set record April sales and engagement for Xbox One last month," said Xbox marketer Mike Nichols. "Xbox One console sales in the U.S. increased 63 percent in April 2015 compared to April 2014 and Xbox Live comparisons showed the number of active global users (Xbox One and Xbox 360) grew 24 percent."
Sony released a statement thanking fans for their support, adding that "PlayStation continues to lead software sales for April 2015 and PS4 remains the cumulative sales leader in the U.S."
Nintendo offered a statement that sales of its Wii U and 3DS hardware systems have collectively "increased by nearly 50 percent" for April, year-on-year. The company added that total Wii U sales in 2015 "increased by nearly 15 percent over sales during the first four months of 2014," with sales of Super Mario 3D World now more than 2 million in the United States.
In the software charts, which do not count digital downloads, Mortal Kombat X led against chart stalwarts and sports updates like Grand Theft Auto 5, Battlefield: Hardline, MLB 15: The Show, Minecraft and NBA 2K15.
According to Nintendo, new 3DS release Xenoblade Chronicles 3D was the fifth best-selling game in April on a single platform. NPD's game sales charts are multi-platform based.
Overall console and physical game sales were up 3 percent year-on-year from $580 million to $596 million with game sales up 13 percent year-on-year to $228 million.


Size 2 Disney Frozen - Olaf Children's Spring/Autumn Pyjamas.
This two piece Disney Frozen - Olaf pyjama set is 100% cotton. These Olaf pyjamas have a long sleeved top with an Olaf print, round neckline and come with matching pink long pants. Great pyjamas for Disney Frozen fans.
These Olaf Pyjamas are also available in Size 3, Size 4, Size 6, Size 8, and Size 10.


AMW Reviews: D'Haus House of Aroma Moroccan Argan Oil + Giveaway --- CLOSED!!!
Argan Oil is an all-natural, 100% organic, chemical-free beauty marvel that really works. Produced from the Argan tree in semi-deserts of Morocco, it is extracted from the kernels of its fruit. Argan oil comes loaded with essential fatty acids like linoleic acid, a precursor for Vitamin E. This makes it well-known for its anti-aging, moisturizing and antioxidant properties. It is found to contain 700mg per kilogram of tocopherois that is twice the amount found in olive oil.
Easy to use pump glass bottle.
As seen on ingredients list, consists of ALL NATURAL Argan Oil, nothing else!
Gets absorbed into the skin pretty well.
Multi-functional: Can be used on hair, face and body.
A little amount goes a long way!
Skin feels soft and lesser lines can be seen.
If used on hair, the ends of the hair doesn't feel as dry!
Moisturizes also the skin around my nails!
No skin irritations nor allergic reactions.
The scent! Don't discriminate the brand as I talked to friends who are Moroccan Argan Oil users and I was told pure Argan Oil doesn't smell the greatest!
Not widely available. For now, they are available in their Ortigas store.
Everything about D'Haus House of Aroma Moroccan Oil is what I need to help soothe my very dry, parched skin and hair! Again, the only concern on my part is the scent (as I have a nose of a dog! *laughs*) But the scent goes away after a couple of minutes!
If you plan to apply this on your hair, concentrate only on the drier ends and use around a pump or 2.
Leave the Argan Oil on your hair the night before you go to bed, so you can wake up with moisturized hair in the morning before you take a shower.
1 pump is enough for the face and neck. 2 pumps are enough for both arms and another 2-3 pumps for the legs!
With the remaining Argan Oil on your hands, massage your fingertips.
Best to apply the Moroccan Argan Oil on your body after shower.
Since packaging looks really nice, this is best to give this as gift to friends and loved ones!
If you have dry areas or allergy spots (like I do), massage with a tiny amount of D'Haus Moroccan Argan Oil as it helps soothe itchiness at the same time, speeds up healing.
Anyone who have dry, sensitive skin that needed moisture that locks for a couple of hours to a day! Best for dry, frizzy, unruly hair!
20ml costs Php750.00 (approx $17.50).
You can immediately see the blurring effect of my lines.
As stated, 2 AMW readers may get the chance to win their own D'Haus House of Aroma Morrocan Argan Oil! PLEASE read mechanics carefully on how to join!
Comment in this post together with your name and email address.
Like D'Haus House of Aroma on Facebook.
Contest starts today ends June 10, 2012 11:59pm.
2 winners will be picked via Fruit Machine. Names of the 2 winners will be posted in this post and will be emailed for notification.
A reply will be needed within 48 hours or a new winner will be picked.
Open to Philippine Residents. Prize will be shipped by D'Haus.
Thanks to CJ of D'Haus Home & Decor International!
Hi Ms. Nikki.. Thanks for this giveaway.. I would love to try the Argan Charcoal Detox Soap with 24k Gold Flakes, because this soap has all the things that my skin needs - renews skin's elasticity, repairs sun damage and rich with anti-aging properties.. Now that's what i call soap!
I would like to try the Argan Massage oil, aside from I am overdue for a body massage iit would be so nice to have this on my drawer anytime I needed a massage and can't go right away and visit the spa.
I would want to try the Aroma Moroccan Oil because I have also been battling for months now with my dry and very sensitive skin. Also, I would want to try their Calming Sound Sleep. I find it very innovative, as this product will be sprayed to the pillow before hitting the stack. Nothing beats a good sleep and rest. Not only it contributes on having a beautiful aura when you wake up, but is one necessary factor that could keeping you healthy both mind and body.
I want to try the argan massage oil,because i want to feel relax and rejuvenated and at the same time moisturize my skin every time i went home after a stressful day at the ofice.
Wow, I was just looking at essential oils last Sunday, and now you have this review. Thanks for this!
So aside from the Moroccan Argan Oil, I would also like to try the Home Fragrance oil.
I'm an avid fan of Moroccan argan oil because it really works for me (it really does lighten my scars).
After reading your review, I guess I would like to switch another brand for my moroccan argan oil!
Aside from the moroccan argan oil, I would also lke to try H'haus Calming and Soothing Sound sleep, because it is really hard for me to sleep early and on time and this product sounds unique for me!
I want to try the Sandalwood Reed Diffuser. Reed diffusers are great when it comes to invigorating your home with their calming fragrance. And with the Sandalwood scent, I couldn't ask for more.
Aside from the Moroccan argan oil, I would like to try the Charcoal soap with 24k gold. It sounds so interesting!
Aside from the Moroccan Argan Oil, which D'Haus product would you want to try?"
Thanks for your review, i am using Argan oil for my hair and face but different expensive brand. I'll try this next time.
Aside from argan oil, i want to try the sleep sound product, sounds good too, i sometimes have problem falling asleep so i'll give it a try later.
I would like to try the Aromatic Room Spray in Jasmine & Sandalwood scent.
Hi nikki would love to try the argan natural cleansing oil. Lately I've been experimenting on what make up remover would suit me well. Thanks for sharing the giveaway!
I would like to try their Argan massage oil to relieve tension and stress.
I would like to try their Exotic tea because I am a tea lover. And also their packaging is really nice.
I would like to try their Exotic Tea,since I am a tea lover. And I love their packaging!
Would love to try their geranium/ orange/ vanilla room spray, 3 if my fav scents in one!
I would like to try their calming sound sleep spray because I have a hard time sleeping at night especially during summer vacation.
I would like to try their calming sound sleep because I always have a hard time sleeping. If I win, I can share this to my husband who like me has irregular sleeping habit.
i would like to try their line of soap most specially the Charcoal detox soa because i have a brown skin and i want to be lighter.
I would like to try their Aromatic Room Spray Collection, specifically, Jasmine & Sandalwood. I'm a big fan of room sprays and I would like to use this in my room!
i'm intrigued by the gemstone therapy body scrub gels.
I would like to try the Argan Oil Spa Package to complete my argan oil experience.
I've bought this one before and I really live the scent.. Thanks for the review, it adds me more information about this product.
I wpuld like to try gemstone theraphy body scrub gels.I always fond of body scrubs.
i'd go for their essential oils like bergamot and lavender.
Aside from the Moroccan Argan Oil, i would love to try Argan Nourishing Day & Night Eye Cream to keep the most sensitive part of my face fresh looking.


Digital Business Success Checklist... • Across The Pond, Live!
Have you ever wondered what it takes to start advertising and selling online? If you already own a brick-and-mortar business and you've been relying on traditional marketing, advertising, sales, and fulfillment – then this may be the most important article you've ever read. And..
If you're an entrepreneur trying to get started selling products online, then we're certain you're going to find that this is one of those resources that keeps bringing you back over and over again.
A HUNGRY AUDIENCE – there's nothing more important to your business than a flock of hungry and enthusiastic buyers. If you already own a business, now is the time to refine your current customer list to the very best. If you are just getting started, then you'll want to research niches and micro-niches to find the audience that'll eat up your offer!
AN OFFER THEY CAN'T REFUSE – this isn't giving things away for free, it's putting together an offer they want so badly they're willing to crawl through broken glass to get. These offers can be information, physical goods, an experience, or services.
A domain provider – this is the service that lets you buy and maintain "YourStoreSite.com" from now to the end of your business.
A web host – this is the service that makes sure everyone that wants to see your website and online offers can. Having one with an excellent reputation and reasonable prices (with fantastic service) is paramount.
A payment processor – look, you can't very easily take cash through the internet…so, you'll need someone to help process payments for you.
A PREFERRED CHANNEL / DISTRIBUTION OUTLET – okay, okay… you're right! Our podcast and services are all about digital marketing, so a website it where most will pick to have the transaction completed and digital products exchanged during the sale. But, what about physical products or services? What platform, service, tool, or distributor will you use to get your goods & services to your customer?
That's it. Can you believe it? Above is the list of the four most critical things you'll need for a successful business.
Now, what about the most effective use of your time? Well, that's easy!
Once you get the checklist above sorted out, you'll want to focus your energy on the five areas below. And, while you're just starting out, doing ANYTHING outside of these five things is a complete waste of your time and your energy. In fact, this is so important that it has been the topic of discussion during costly coaching sessions with businesses owners around the world. And, this is a topic that so important, it will keep coming up over and over on the podcast.
MARKETING & ADVERTISING – this is the process of getting in front of your ideal customer with your offer. Going further, it's about building a list of potential hungry buyers (leads) so that you can continue to present your offer over and over again.
Success With Email Solo Ads And How to Avoid Being Duped.
PROMOTIONS – this is the process of letting your potential customers try you before they buy you. These promotions mean a trial offer, a presentation where you demonstrate the product or service, or some other way for your potential customer the opportunity to get to know you and how your solution might work for them.
SALES – this is the simple process of exchanging money for goods and services. Please don't make this any harder than it has to be. But, this is the process that gives you the revenue you need to keep your business growing – so it's super important!
FULFILLMENT – this is the process of giving your customer the products and services for which they paid. Fulfillment is accomplished through a process of sending items in the mail, a freight or shipping business, delivering something for download, or as advanced as a membership site. No matter the platform or method, you'll want to concentrate on making this experience amazing for your customers.
AFTER SALES CARE – this is the process of showing your appreciation for your customers and taking care of their needs. To some, this might look like a customer support platform or a series of phone calls, emails, and messages you send after your customers buy your products or services. Without this, getting repeat customers is almost impossible. And, generating new customers is by far much harder than simply keeping the good customers you already have.
As the son of a Fuller Brush Salesman turned middle manager, I went rogue and did the unthinkable – I got an engineering degree. Early in my career I quickly rose to leadership positions and ended up as the youngest partner of my fourth employer.
But, the itch to sell overwhelmed me and my DNA was showing up everywhere. As a young entrepreneur, I was selling my own professional services to consumers and businesses as a computer consultant to put myself through college. Then, after going into engineering, when the technical work was done for the day, I'd pinch hit for our marketing teams. This quickly became a skill as we continued to rack up the wins. I love to win and we won big!
I have been on more once-in-a-lifetime projects as technical staff, project manager or as a principal than one professional should be blessed with. I've worked on huge bridges, long underground train systems, and complex water resources projects. All have been won with a clever combination of words, presentation, reputation, and many ounces of technical skill.
In all this, I've come to appreciate making the complex simple and communicating directly to the decision makers in words they understand with benefits they appreciate. And, I love working on teams the continue to win. I know that working together will make winning faster and easier for you and I'm excited to get started on your next project.
Digital Main Street Media – dedicated to helping local businesses make the most of the internet to increase leads and sales.
AEC Professional Matters – all things B2B Marketing and B2B Copywriting. This site gives you direct access to the leader in civil engineering copywriting, architecture copywriting and construction copywriting.
Hey Chad! Great having you here. Thanks for the thumbs up! Be sure to subscribe to the podcast, make comments on the episodes, ask questions, and share with your friends and different groups you're in! Way to go!


Teams PAS Giannina Olympiacos played so far 26 matches.
PAS Giannina won 4 direct matches. Olympiacos won 19 matches. 3 matches ended in a draw. On average in direct matches both teams scored a 3.31 goals per Match.
PAS Giannina in actual season average scored 0.79 goals per match. In 9 (56.25%) matches played at home was total goals (team and opponent) Over 1.5 goals. In 4 (25.00%) matches in season 2019 played at home was total goals (team and opponent) Over 2.5 goals.
Olympiacos average scored 1.96 goals per match in season 2019. In 21 (75.00%) matches played away was total goals (team and opponent) Over 1.5 goals. In 12 (42.86%) matches played away team was total goals (team and opponent) Over 2.5 goals.
STREAKS FOUND FOR DIRECT MATCHES!!» Olympiacos played 9 matches in a row without draw.
We invite you to check PAS Giannina and Olympiacos match statistict (Tab Stats->Match statistics), where you will find out who is the best scorer. Also you can check the statistics of possession, shots, corners, offsides, and many other applications.
In tab Goals stats (tab Stats->Goals stats) check how many loses and scored goals per game, how many games won and lost to zero. You will find what results teams PAS Giannina and Olympiacos usually end matches with divided into first and second half.
In tab Form(Stats->form) you find graph teams form and a list of all matches of PAS Giannina and Olympiacos in season.


In this age, Information Technology is encompassing all walks of life. Cyberspace has brought transition from paper to paperless world. Cyber law touches almost all aspects of transactions and activities involving the internet, World Wide Web and cyberspace in all walks of day to day life. Every action and reaction of cyberspace has some legal and cyber legal angles.
The call for paper aims at, mind provoking panel discussion sessions by eloquent writers, providing knowledge and sharing their vision and experiences on the subject.
CYBERLEKH PUBLICATIONS[an imprint of cybertalkindia] invites Research papers, Articles, Short Notes, Case Commentaries and other such for its book set to be published in September 2018 Bearing ISBN.
The last date for the submission is 20th August 2018. Notification of the accepted papers will be done on/ before 19th August 2018.
For Hard Copy of Book INR 500 per copy will be charged extra by the author.


Whether you are hosting a community Breakfast With Santa event, a Christmas Tree Lighting for your shopping center, or trying to create some holiday fun for your entertainment or resort property, the goal is the same. To bring people together.
My Christmas Special is a winter wonderland of hilarious comedy, dazzling holiday magic, spectacular balloon creations, and audience participation, with more fun than you can fit in Santa's sleigh! A magical family entertainment experience that is guaranteed to put your audience in the holiday spirit.
To start a new tradition at your annual holiday event, click on the snowflake below.
Easter is such a fun holiday, and yet no one seemed to have a fun live Easter-themed show for kids and families. So I created one!
To bring some EGG'stra fun to your upcoming event, just click on the Easter Egg below.
Booking great family entertainment this Halloween season doesn't have to be scary.
My Halloween Balloon SPOOK'tacular is filled with lots of ghoulish giggles and hocus-pocus. A delightfully, frightfully good time for little monsters of all ages!
*Not responsible for any damages resulting from zombie attacks or poltergeist activity during this program. If you experience ghosts, hauntings, or hexes persisting for more than three days, please contact your witch doctor immediately.
To learn more about this program click on the pumpkin below, if you dare!


Tag @JACL_DC on Twitter and @JACLNational and @SaveTuleLake on Facebook and together we hope to demonstrate to Modoc County that the Japanese American community is united in opposition to this egregious infringement upon a vital part of our nation's civil rights history.
For more information on the fence please see here.
Read Executive Director David Inoue's letter here..
Read Regional Director Patty Wada's letter here..


This randomized phase III trial studies how well combination chemotherapy with or without ganitumab works in treating patients with newly diagnosed Ewing sarcoma that has spread to other parts of the body. Immunotherapy with monoclonal antibodies, such as ganitumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as vincristine sulfate, doxorubicin hydrochloride, cyclophosphamide, ifosfamide, and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether combination chemotherapy is more effective with or without ganitumab in treating patients with newly diagnosed Ewing sarcoma.
To determine if the event-free survival (EFS) in patients with newly diagnosed metastatic Ewing sarcoma treated with multiagent chemotherapy is improved with the addition of ganitumab (AMG 479).
To describe the toxicity of the addition of ganitumab to multimodality therapy for patients with newly diagnosed metastatic Ewing sarcoma.
II. To compare overall survival in patients with newly diagnosed metastatic Ewing sarcoma treated with multiagent chemotherapy with and without the addition of ganitumab.
To compare bone marrow response rates in patients with newly diagnosed metastatic Ewing sarcoma treated with multiagent chemotherapy with and without the addition of ganitumab.
II. To describe the toxicity of 6 months of ganitumab monotherapy as maintenance therapy following multimodality therapy in patients with newly diagnosed metastatic Ewing sarcoma.
III. To describe trough levels of ganitumab in a cohort of patients with Ewing sarcoma < 21 years of age treated with 18 mg/kg.
IV. To describe the feasibility of and local failure rates following hypofractionated stereotactic body radiotherapy (SBRT) directed at bone metastases in patients with newly diagnosed metastatic Ewing sarcoma.
To determine if EFS, overall survival, bone marrow response rates, and toxicity differ based on serum markers of the insulin-like growth factor 1 (IGF-1) pathway in patients with newly diagnosed metastatic Ewing sarcoma treated with interval compressed chemotherapy with and without the addition of ganitumab.
VI. To determine if EFS, overall survival, and bone marrow response rates differ based on protein, deoxyribose nucleic acid (DNA), and ribonucleic acid (RNA) marker in patients with newly diagnosed metastatic Ewing sarcoma treated with interval compressed chemotherapy with and without the addition of ganitumab.
VII. To evaluate bone marrow micrometastatic disease and tumor cell surface IGF-1R expression at diagnosis and after 3 and 6 cycles of study therapy in patients with newly diagnosed metastatic Ewing sarcoma.
VIII. To determine if the presence of germline polymorphisms in EGFR correlate with response to multiagent therapy with and without ganitumab.
IX. To investigate the ability of fludeoxyglucose F 18-positron emission tomography (FDG-PET) to augment conventional response assessment of primary Ewing sarcoma tumors by magnetic resonance imaging (MRI).
To explore FDG-PET response at the primary tumor as a prognostic marker and as a predictive biomarker of clinical activity of IGF-1R inhibition in patients with newly diagnosed metastatic Ewing sarcoma.
XI. To collect data on institutional testing for Ewing sarcoma breakpoint region 1 (EWSR1) translocation status in patients enrolling on study.
XII. To explore the capacity of plasma cell-free DNA analysis to detect tumor-specific genetic changes at initial diagnosis and after initiation of protocol therapy.
XIII. To collect a population of bone marrow metastatic tumor cells by flow cytometry for genomic profiling.
OUTLINE: Patients are randomized to 1 of 2 treatment regimens.
INDUCTION THERAPY: Patients receive vincristine sulfate intravenously (IV) over 1 minute on day 1; doxorubicin hydrochloride IV over 1-15 minutes on days 1 and 2; and cyclophosphamide IV over 30-60 minutes on day 1 of weeks 1, 5, and 9; and ifosfamide IV over 1 hour on days 1 to 5 and etoposide IV over 1-2 hours on days 1 to 5 of weeks 3, 7, and 11.
LOCAL CONTROL THERAPY: Between weeks 13-18, patients undergo surgery and/or radiation therapy.
CONSOLIDATION THERAPY: Patients receive vincristine sulfate IV over 1 minute on day 1 of weeks 1, 7, 9, and 13; doxorubicin hydrochloride IV over 1-15 minutes on days 1 and 2 of weeks 1 and 7; cyclophosphamide IV over 30-60 minutes on day 1 of weeks 1, 7, 9, and 13; ifosfamide IV over 1 hour on days 1 to 5 of weeks 3, 5, 11, and 15; and etoposide IV over 1-2 hours on days 1 to 5 of weeks 3, 5, 11, and 15.
METASTATIC SITE IRRADIATION: Patients with lung metastases undergo definitive SBRT or external beam radiation therapy (EBRT) over 5 days.
INDUCTION THERAPY: Patients receive Induction therapy as in Regimen A and receive ganitumab IV over 30-60 minutes or 60-120 minutes on day 1 of weeks 1, 3, 5, 7, 9, and 11.
CONSOLIDATION THERAPY: Patients receive Consolidation therapy as in Regimen A and ganitumab IV over 30-60 minutes or 60-120 minutes on day 1 of weeks 7, 9, 11, 13, and 15.
METASTATIC SITE IRRADIATION: Patients with lung metastases undergo definitive SBRT or EBRT over 5 days.
MAINTENANCE THERAPY: Patients receive ganitumab IV over 30-60 minutes or 60-120 minutes on day 1 in weeks 1, 4, 7, 10, 13, 16, 19, and 22.
After completion of study treatment, patients are followed for 10 years.


text:
Vecuronium Bromide Injection For Care Muscles
Vecuronium bromide CAS 50700-72-6 injection formuscle relaxants Product Name: Vecuronium bromide Synonyms:...
Vecuronium bromide CAS 50700-72-6 injection formuscle relaxants
Synonyms: norcuron;1-(3-alpha,17-beta-diacetoxy-2-beta-piperidino-5-alpha-androstan-piperidiniu;17beta-diol,16beta-pipecolinio-2beta-piperidino-5alpha-androstan-3alphbro;mide,diacetate;nc-45;orgnc45;vecuronium;VECURONIUM BROMIDE
MF: C34H57BrN2O4
MW: 637.73
EINECS: 256-723-9
Mol File: 50700-72-6.mol
White or almost white powder, odorless, bitter taste, have cited moist. Highly soluble in ethanol, slightly soluble in water, almost insoluble in ether; very soluble in dilute hydrochloric acid.
What is Vecuronium bromide?
Vecuronium bromide, sold under the brand name Norcuron among others, is a medication used as part of general anesthesia to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is also used to help with endotracheal intubation; however, suxamethonium (succinylcholine) is generally preferred if this needs to be done quickly. It is given by injection into a vein. Effects are greatest at about 4 minutes and last for up to an hour.
Side effects may include low blood pressure and prolonged paralysis. Allergic reactions are rare. It is unclear if use in pregnancy is safe for the baby. Vecuronium is in the aminosteroid neuromuscular-blocker family of medications and is of the non-depolarizing type. It works by blocking the action of acetylcholine on skeletal muscles.
Main Functions:
vecuronium bromide is one of muscle relaxant most commonly used in liver transplantation. It is metabolized mainly by liver and then discharged in prime type by biliary passage system.
Intermediate-acting non-depolarizing muscle relaxants , strong muscle relaxant effect . Its duration is shorter , faster recovery , and does not cause bronchospasm and decrease in blood pressure , had little effect on the cardiovascular system . For endotracheal intubation and surgery .
How dose Vecuronium bromide works?
Vecuronium operates by competing for the cholinoceptors at the motor end plate thereby exerting its muscle-relaxing properties which are used adjunctively to general anesthesia. Under balanced anesthesia, the time to recovery to 25% of control (clinical duration) is approximately 25 to 40 minutes after injection and recovery is usually 95% complete approximately 45 to 65 minutes after injection of intubating dose. The neuromuscular blocking action of vecuronium is slightly enhanced in the presence of potent inhalation anesthetics. If vecuronium is first administered more than 5 minutes after the start of the inhalation of enflurane, isoflurane, or halothane, or when a steady state has been achieved, the intubating dose of vecuronium may be decreased by approximately 15%.
History of Vecuronium bromide:
As long ago as 1862, adventurer Don Ramon Paez described a Venezuelan poison, guachamaca, which the indigenous peoples used to lace sardines as bait for herons and cranes. If the head and neck of a bird so killed was cut off, the remainder of the flesh could safely be eaten. Paez also described the attempt of a Llanero woman to murder a rival to her lover's affections with guachamaca and unintentionally killed 10 other people when her husband shared his food with their guests. It is probable that the plant was Malouetia nitida or Malouetia schomburgki.
The genus Malouetia (Family Apocynaceae) is found in both South America and Africa. The botanist Robert E. Woodson Jr comprehensively classified the American species of Malouetia in 1935. At that time, only one African species of Malouetia was recognised, but the following year Woodson described a second: Malouetia bequaertiana, from the Belgian Congo.
It was in 1960 that scientists reported the isolation of malouetine from the roots and bark of Malouetia bequaertiana Woodson by means of an ion exchange technique. A pure form of the substance was first synthesised in 1964, and was named pancuronium bromide. The name was derived from p(iperidino)an(drostane)cur(arising)-onium.
A paper published in 1973 discussed the structure-activity relationships of a series of aminosteroid muscle relaxants, including the mono-quaternary analogue of pancuronium, later called vecuronium.
Non-medical use of Vecuronium bromide:
Vecuronium bromide has been used as part of a drug cocktail that prisons in the United States use as a means to put a condemned prisoner to death. Vecuronium is used to paralyze the prisoner and stop his or her breathing, in conjunction with a sedative and potassium chloride to stop the prisoner's heart. Injections of vecuronium bromide without proper sedation allow the person to be fully awake but unable to move in response to pain.
In 2001, Japanese nurse Daisuke Mori was reported to have murdered 10 patients using vecuronium bromide. He was convicted of murder and was sentenced to life imprisonment.
COA of Vecuronium bromide:
SPECIFICAITONS
White, yellowish-white or slightly pink crystalline powder
White crystalline powder
1) The IR absorption spectrum of the sample is concordant with that of Pancuronium Bromide standard
2) It gives reaction of bromides
Specific optical rotation
+38.0°~+42°
Appearance of solution
Clear and colourless
Related Substances (TLC)
Impurity A NMT 1.0%
Impurity D NMT 1.0%
any other impurities NMT 0.1%
NMT8.0%
Sulphated ash
98.0~102.0%
Conclusion: It conforms to the EP STANDARD.
Adjuvant is mainly used for surgical anesthesia,Pregnant women and children should not be used.
PRL-8-53
NSI-189 phosphate
CDP-Choline
Alpha GPC(Choline Alfoscerato)
Carphedo(Phenylpiracetam)
Hydrafinil(9-fluorenol)
Galantamine Hydrobromide
Tianeptine sodium salt
Tianeptine free acid
Tianeptine sulfate
Pikamilone
Compound 7P;
2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide
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Hi Dolls! This will be a short posting week because I will be heading out of town to attend my MIL's wedding (mother-in-law) and so I need to start packing and getting things done before we leave on Thursday. I will be posting via instagram and facebook mostly and some posting here via my ipad.
Not only am I attending but I am a bridesmaid :-/ and although I love them to pieces I rather just attend the wedding you know? I am also less then excited about flying into Omaha in the winter, LOL!!!
So cute, and I love the way the pink pops. Have a great day.
I love the striped sweater! and what can I say about the fur vest, so cool. I've been wanting one like that forever, except when I think about it I am not even sure I would be even able to wear it here with how dang cold it is, but I still want one. Lol.
That is a beautiful sweater. I love the bright pink against the navy blue.
<3 that sweater! I knew I recognized it from somewhere-I was thinking either J Crew or the Gap.
I hope you have a good time at the wedding.
love the outfit!!!!What color shoe's did you wear?
Yup that is cute sweater. <3 the vest too!
Super cute & chic! Just my style!
I can't wait to see your bridesmaid dress! You better kill it!
Another loved ensemble! Have a safe and fun trip.
Looooooooooove this sweater!!!!! Awesome outfit as usual!
I love the sweater! There is so much I could do with it! Looking good!


Henry Joseph Jack (1869 - 1946), one of the "Dolgarrog People".
Jack was born in Swansea on 9th October 1869. His father, Henry, a Maltster, died in 1879 aged 46, leaving HJJ's mother to raise him and his brother John. At the 1891 Census he was still living in Swansea as a wine merchant's traveller. He married a widow, Emily Hilton (nee Burn) on 2nd November 1891.
At the April 1901 Census, he was Managing Director of a wholesale dairy company and living in Bridgwater. The Cashier at the dairy was a boarder at his address. The dairy was being built that year under the name of British Dairies and came into the ownership of J. Higgs & Co. Ltd, set up in October 1901, Jack being a director and shareholder. In early 1902 Jack became Managing Director of Higgs's Farm Dairies Ltd which had been incorporated in 1898 to acquire a dairy business in Kennington, South London inherited by John L Higgs from his father. A prospectus was issued in May 1902 to acquire several dairies, including the one at Bridgwater. Jack was described as a dairy manager and as having 'many years experience in the trade'. However the business failed due, Higgs claimed, to trying to carry on too many businesses. In March 1903 creditors obtained an order for compulsory winding up. The Official Receiver and his assistant concluded that the business had traded at a loss and the company's transactions had not been sufficiently recorded. Also that there were omissions from the disclosures in the prospectus. Jack had resigned in December 1902 before the crash.
By 1909, he is recorded as being in Colwyn Bay, and involved with the reconstituted Aluminium Corporation at Dolgarrog. By 1915, he was the Managing Director, and living at Maenan Manor, Llanrwst. In 1920 Jack was elected as a member of Caernarvonshire County Council, later becoming Chairman.
In 1918 the Aluminium Corporation acquired a controlling interest in the North Wales Power and Traction Co. Ltd with which came the PBSSR. In April 1920 it gained control of the North Wales Narrow Gauge Railways (NWNGR), and in July 1921 control was obtained by Jack and his colleagues of the Festiniog Railway. The Snowdon Mountain Railway was also acquired.
As a result of this, Jack was now in control of all the passenger carrying narrow gauge railways of that part of North Wales.
On 18th October 1921, the Light Railway Commissioners held a public inquiry into the Dolgarrog regime's plans for the Welsh Highland Railway. The Chairman of the Commissioners was quite blunt and told Jack that many local people held him in suspicion, being both a member of the County Council and in control of all the railways that were to make up the greater Welsh Highland/Festiniog empire. The Chairman told him that many people felt he wielded far too much influence, indeed it seems that Jack was always regarded as an upstart and an outsider from South Wales.
The Public Inquiry went the way of the railway and on 1st March 1922, Jack, together with Sir John Henderson Stewart and Evan R. Davies became the first directors of the Welsh Highland Railway (Light Railway) Company. As was to be expected, the new board were very upbeat about the future of the new empire and in the North Wales Chronicle, Jack stated that the WHR desired to put the railways in such a state that they would not continue to be a disgrace to the county. Jack predicted an upturn in the slate industry, but also suggested that the WHR would be most reliant on holiday traffic. He cannot be blamed for failing to foresee the terminal failure in the slate industry, but he did have the foresight to see the possible earnings from tourist travel.
The April 1924 AGM was a stormy affair and Jack was made the scapegoat for the losses made from the start of operation. Jack cannot be blamed for failing to predict the cut throat rates that local bus operators were charging which were putting each other out of business, never mind the impact they were having on the rail passenger traffic. The recipts from the FR were similarly down. Jack took the blame for the lack of success of the WHR and resigned with effect from 1st November 1924, being replaced by the company's engineer, Colonel Holman F. Stephens, who became chairman and managing director during 1925. This marked the end of the Dolgarrog regime on the railways.
The most visible and enduring impact that Jack had on the WHR was the result of his insistence that the stock be cut down to run through the Moelwyn Tunnel on the Festiniog line. As a result, Moel Tryfan and the carriages were cut down successfully, but Russell was butchered in vain and only once ran above Boston Lodge following the modifications.
Completing the story of Jack's career in North Wales, on the 2nd November 1925 disaster struck the village of Dolgarrog. The Eigiau Dam of the Aluminium Corporation collapsed, water having leaked under the dam which itself largely remained intact. The water poured into the Coedty Reservoir which being small was unable to hold it. The dam of that reservoir failed and the power station and the village of Dolgarrog, one mile below, were engulfed. Most of the villagers were in the Assembly Hall for the weekly film show and so escaped, being on higher ground. Sixteen lives were lost as a result of the collapse.
Jack emerged badly from this affair and in 1928, having resigned from the Aluminium Corporation, and NWPT, he left Dolgarrog. With, firstly, an accomodation address in London, he subsequently moved to 9 Grosvenor Gardens, Westminster. In 1933 he changed his name to Henry Jack Macinnes. His first wife's death, in late 1936, was registered in Worthing, Sussex.
In the latter half of the 1930s he was living in Holmdene, Fairford, Gloucestershire, and still held a majority of the WHR shares (52,391 Ordinary shares). He remarried, in mid 1942, to a Charlotte P Brezzie, approximately 20 years his junior. He remained Chairman of the SMR until 1945, and died, at the age of 77, in early 1946 in Tonbridge, Kent. A valuation of his estate, appeared in The Times newspaper, to the value of £63,458.
For a reappraisal of Jack by Peter Johnson see FR Heritage Group Journal No. 126 of Summer 2016.
Boyd, James I.C. (1975) . The Festiniog Railway 1800 - 1974; Vol. 1 - History and Route. Blandford: The Oakwood Press. ISBN 0-8536-1167-X. OCLC 2074549. Boyd, James I.C. (1986) . Narrow gauge railways in North Caernarvonshire. Volume 1, The West. Oxford: The Oakwood Press. ISBN 085361-273-0. OCLC 14641039.
This page was last edited on 5 March 2019, at 19:38 (UTC).