text:
IBM Plex is an open source typeface superfamily conceptually designed and developed by Mike Abbink at IBM in collaboration with Bold Monday to reflect the design principles of IBM and to be used for all brand material across the company internationally. Plex replaces Helvetica as the IBM corporate typeface after more than fifty years, freeing the company from extensive license payments in the process.

Version 1.0 of the font family had four typefaces, each with 8 weights (Thin, Extra Light, Light, Regular, Text, Medium, Semi-bold, Bold) and true italics to complement them.

 IBM Plex Sans – A grotesque sans-serif typeface with a design that was inspired by Franklin Gothic. Other sans-serif classifications were rejected on the basis of being too soft (humanist), inefficient (geometric) and overly perfected (Neo-grotesque). Some of Franklin Gothic's features such as the angled terminals, a double-storey g and a horizontal line at the baseline of the 1 are used in IBM Plex Sans. On 7 April 2019, IBM Plex Sans Variable, a variable counterpart to IBM Plex Sans was released.
 IBM Plex Sans Condensed – A condensed variant of IBM Plex Sans.
 IBM Plex Mono – A monospaced typeface based on IBM Plex Sans. The italic design was inspired by the Italic 12 typeface used on the IBM Selectric typewriter; this is particularly evident with the italicised i, j, t and x letters.
 IBM Plex Serif – A transitional serif typeface with a design that was inspired by Bodoni and Janson. Other serif classifications were rejected for being too humanist and outdated (old-style) and too clunky and unrefined for long text (slab-serif). Some of Bodoni's features such as ball terminals and rectangular serifs are used in IBM Plex Serif.

Unicode coverage
As of version 1.0 the IBM Plex typefaces support over 100 languages with most that use the Latin alphabet (including Vietnamese), as well as Cyrillic (except in IBM Plex Sans Condensed). In version 3.0 of IBM Plex Sans, support for monotonic Greek was added. For other writing systems separate fonts were made without italics:

 IBM Plex Sans Hebrew – Adding support for the Hebrew writing system.
 IBM Plex Sans Thai – Adding support for the informal loopless Thai script, released on 15 October 2018.
 IBM Plex Sans Thai Looped – Adding support for the formal looped Thai script, on 5 April 2019.
 IBM Plex Sans Devanagari – Added support for the Devanagari writing system, released on 14 December 2018.
 IBM Plex Sans Arabic – Added support for Arabic script, released on 13 March 2019.
 IBM Plex Sans Korean – Added support for the Hangul alphabet, released on 8 June 2020.
IBM Plex Sans Japanese – Added support for Japanese writing system, released on 24 July 2021.

In addition, both Mike Abbink and Bold Monday have confirmed to be working on support for CJK, Bengali, Tamil and Kannada.

There is also support for common mathematical and currency symbols (including Bitcoin (₿) #U+20BF which was ratified into Unicode in 2017) as well as ligatures such as fi and fl, along with stylistic alternates for a, g and 0.

There are a few unreleased symbols for IBM Plex Sans Condensed, IBM Plex Mono and IBM Plex Serif such as the generic currency sign (¤), prime symbol (′) and double prime symbol (″). In addition Mike Abbink has confirmed support for the Mathematical Operators block and support for the symbols used in the APL programming language in 2019.

The FCC #EFCC and CE marking #ECE0 logos are encoded as glyphs within the Private Use Area. Prior to version 1.0, five IBM logos (solid and 8-bar logos, and the I-Bee-M logo) #EBE1 to #EBE7 were also encoded as glyphs.

Licensing
IBM has licensed the font files only under the SIL Open Font License (SIL OFL). Between 9 August 2018 and 21 August 2018, the fonts were also dual-licensed under the Apache License. This dual-licensing arrangement was rescinded due to concerns that the Apache License is unsuitable for fonts. The SIL OFL license is free and open-source, but building the fonts from source requires FontLab Studio, which is proprietary software.

Bold Monday also provide web development code in CSS, SCSS and JavaScript that is related to the fonts under the Apache License.

IBM Plex's name is reserved, as allowed by the SIL OFL, and trademarked as of December 2017.

See also
 Overpass - the open-source font family of Red Hat
 Segoe
 Roboto
 Product Sans
 San Francisco

References

External links
 GitHub page
 Official site
 IBM Plex Sans on Google Fonts
 IBM Plex Sans Condensed on Google Fonts
 IBM Plex Mono on Google Fonts
 IBM Plex Serif on Google Fonts

Plex
Typefaces and fonts introduced in 2017
Unified serif and sans-serif typeface families
Corporate typefaces
Open-source typefaces
Transitional serif typefaces
Grotesque sans-serif typefaces
Monospaced typefaces
Thai typefaces


Twenty-two-year-old Bryan Widstrand was driving into a parking garage at Concordia University in River Forest, Ill., when 19-year-old Paige Kecseg backed out of a parking spot and hit the passenger side of Widstrand's car. Widstrand contended that the impact caused him to suffer herniated discs at C5-6 and C6-7. In addition, he complained of headaches, neck/back and shoulder pain as well as numbness in his right forearm and two fingers. He also claimed the accident-related injuries caused him to become dependent on pain medicine resulting in rehabilitation at MacNeal Hospital for drug dependency.
The defendant denied that she was negligent and argued that the plaintiff was speeding. Kecseg contended that there were inconsistencies in Widstrand's testimony at trial and denied that he was injured. She pointed to the fact that the plaintiff had gone on numerous trips since the accident, including two visits to Europe and a mountain hiking trip one month prior to the trial.
This case was a one-day "stipulated facts" trial with Judge Michael Panter of the Circuit Court of Cook County. The judge read the medical treatment summary to the jury. The attorney for Widstrand reported that he asked the jury for approximately $150,000 while the defendant's attorney reported that the plaintiff's counsel asked the jury for a verdict of $209,637. The offer to settle before trial was $4,350 with a demand to settle at $100,000.
The jury's verdict in favor of the defendant was entered.
Bryan Widstrand v. Paige Kecseg, No. 11 L 10453 (Cook County).
Kreisman Law Offices has been handling automobile accidents, motorcycle accidents and bicycle accidents for individuals and families who have been harmed, injured or died as a result of the carelessness or negligence of another for more than 37 years in and around Chicago, Cook County and its surrounding areas, including Flossmoor, River Grove, River Forest, Forest Park, Park Forest, Park Ridge, Lake Forest, Chicago (East Side), Chicago (Jefferson Park), Bellwood, Maywood, Summit, Blue Island and Grayslake, Ill.


Shailendra wrote the lyrics Mohammed Rafi, Mukesh, Mubarak Begum, Lata Mangeshkar, Sabita Chowdhury, Asha Bhosle, Ghulam Mohammed , Manna Dey . Download songs from the movie akale 3.
Its better to download songs from net for free. His first guest article in the series on Multiple Version Songs was on Hindi- Marathi, naturally. This is a fastest buffering song site so listen songs without. View credits reviews, tracks shop for the Cassette release of The Golden Collection - Ghazals From Films on Discogs. Gaana offers you free English MP3 songs, unlimited access to over 30 million Hindi Songs, Bollywood Music Regional Music & Mirchi Play.
When I was struggling to look for someone to write on Hindi- Kannada, Arunji surprised me by doing the favour. His father Manzoor Mahmood belonged to Makhdoom Shah Bahaul- Haq of Baba Farid Ganj Shakar dynasty. Good song collection but very ordinary recording. Lata g Ja Gale Se - Lata Mangeshkar.
Listen to all Hindi Albums and Hindi Movie songs on JioSaavn for Free. Download Music Anime, TV Shows, Software , Movies . View credits tracks , reviews shop for the 1996 CD release of The Golden Collection - Duets Of Lata Mangeshkar / Kishore Kumar on Discogs.
All the songs rof high quality very easy to download copy as stated. Pk Lag Ja Gale Se - Lata Mangeshkar.
Collection Lata Mangeshkar Vol 3 Hits 70 S And 80 MP3 songs online free. Golden Collection: Mohd Rafi & Lata Mangeshar super hit songs and ultimate duets. Watch the video for the song ' Feeling Avnavi' from the Gujarati film ' Gujjubhai the Great' sung by Advait Nemlekar and Vibha Saraf Credits. Gaana is the one- stop solution for all your music needs.
The Indian Ex- Servicemen' s Movement ( IESM) spearheading the veterans' one rank one pension ( OROP) demand has correctly applied three of the principles of war albeit in a peaceful struggle, momentum , videos , namely maintenance of aim , images, concentration of force to set themselves on the road to what could be a arch the world' s information, including webpages more. Golden Collection: Mohd Rafi & ta Kishore Vol 3 Golden Collection Songs Download- Listen Lata Kishore Vol 3 Golden Collection MP3 songs online free.
Lata mangeshkar golden collection free download. Lata mangeshkar golden collection free download. Humsafar Ab Yeh Safar Kat Jayega - Lata Mangeshkar Mukesh 5. Sorry, this item is.
The Madhumati soundtrack features eleven songs composed by Salil Chowdhury. Download and listen to Hindi Album & Film songs on JioSaavn. Sign up for a subscription plan to stream ad- free and on- demand. Play the songs playlists , albums podcasts you love on the all- new Pandora. Lata Mangeshkar - The Golden Collection - Lata Mangeshkar Vol 2 ( 2- CD Set) - Music. Listen free to Lata Mangeshkar – The Golden Collection - Lata Mangeshkar, Vol. 34 tracks ( 139: 54). Hindi music album by Lata Mangeshkar, Mukesh 1.
Picktorrent: lata mangeshkar golden collection - Free Search and Download Torrents at search engine. Rafi and Lata Mangeshkar volume 1 Hindi film songs DVD - Music. Download Lata Mangeshkar Golden Collection of Hindi Karaoke Songs.
Na tum humein jaano from Baat Ek Raat Ki ( 1962) lyrics Majrooh Sultanpuri music S D Burman. Download songs from the movie 4 the people 2. Listen to Golden Collection Lata Mukesh songs Online on JioSaavn.
MP3 by Lata Mangeshkar and download Golden Collection Lata Mangeshkar Vol 3. Play Lata Kishore Vol 3 Golden Collection movie songs MP3 by S. Music guitar tabs archive with over 200 tabs for guitar, chords drawning, viola, banjo , bass, guitar notes, drums, 12 key variations , keyboard much more.
The Golden Collection Mohd Rafi & Lata Mangeshkar Vol 1[ cd]. Play golden collection – lata and. I bought CD to listen to the quality music not just lyrics.
Lata mangeshkar golden collection free download. Tum Chal Rahe Ho Hum Chal Rahe Hai - Lata Mangeshkar Mukesh 4. Burman download Lata Kishore Vol 3 Golden Collection songs on n Collection - Lata Mangeshkar & Rafi Free Mp3 Download Golden Collection - Lata Mangeshkar & Rafi Song Free Download Golden Collection - Lata Mangeshkar & Rafi Hindi Album Mp3 Download Golden Collection - Lata Mangeshkar & Rafi Video Download Golden Collection - Lata Mangeshkar & Rafi Free Music Download Aadmi Musafi Hai Ashaon Ke Sawan. Google has many special features to help you find exactly what you' re looking for. Duniya Walon Se Door - Lata Mangeshkar Mukesh 3. Guest article by Arunkumar Deshmukh ( The Living Encyclopaedia needs no introduction to the readers of SoY , Arunji other music related blogs. 3 - Lata Mangeshkar on AllMusic -. उषा मं गे शकर) is an indian singer who has recorded many golden songs of lata mangeshkar free download hindi bengali, marathi .
Play Golden Collection Lata Mangeshkar Vol 3 Hits 70 S download Golden Collection Lata Mangeshkar Vol 3 Hits 70 S 80 songs on. Discover more music concerts, videos pictures with the largest catalogue online at Last. Golden Collection Mohammed Rafi & Lata Mangeshkar - Vol. Lata mangeshkar golden collection free download.
Find Lata Mangeshkar torrents online. Amar akbar anthony are all brothers. Kisi Raah Men Kisi Mod Par - Lata Mangeshkar Mukesh 2. It is said that the Suman Kalyanpur got this solo because of a tiff S D Burman had with Lata Mangeshkar.
Lata mangeshkar golden collection free download. 34 tracks ( 137: 45). Father of Talat Mahmood MANZOOR MAHMOODTalat Mahmood comes from a highly respected and reputed ancestry.
Mp3 download free mp3 song movie The Golden Collection ( ) Various Artists, Direct Download Links Songs. Listen on your mobile phone desktop, TV, smart speakers in the car.
Listen to the songs of Golden Collection Lata Mangeshkar Vol 3 Hits 70 S Listen to your favorite songs of Lata Mangeshkar Mp3 Songs. Welcome to This is a place where you can listen download Hindi, Punjabi, other Indian bollywood song' s karaoke tracks. Golden Collection Lata Mangeshkar Vol 3 Hits 70 S And 80 Songs Download-. Find album reviews stream songs, award information for The Golden Collection: Lata Mangeshkar, credits Vol.
Download and Listen to your favorite. Lata Mangeshkar ( ) Mp3 Songs Download Free while the Music Director of the album is Various Artists. 3 ( Tumhin Mere Mandir Hawa Mein Udta Jaye more).
Freddie Mercury ( born Farrokh Bulsara; 5 September 1946 – 24 November 1991) was a British singer- songwriter, record producer and lead vocalist of the rock band Queen. He is regarded as one of the greatest singers in the history of popular music, and was known for his flamboyant stage persona and four- octave vocal range.
Mercury was born in Zanzibar to Parsi parents from India.


Jaipur is one of the most popular Indian cities and the capital of Rajasthan. Jaipur is popularly known as the Pink City of India that came into existence in 1727. This city is marvels in the form of beautiful colonnaded City Palace complex, museums, gardens and courtyards which attracts visitors from all over the world. Jaipur is surrounded by rich historical and cultural monuments that hold a great significance in the economy of the country.
When it comes to the employment scope for students and professionals the city offers huge employment opportunities. The economy of Pink City is fuelled by tourism, jewellery manufacturing, gems stone cutting, luxury textile, information technology, and education. Jaipur also plays its role as provincial capital, education and administrative centre.
All these industries offer a diverse range of employment opportunities with different skill sets. Besides, the city has a strong retail industry specializing in metal products, antiques, jewellery, handicrafts, carpets, textiles, leather, bangles, pottery and gems etc. Jaipur is a major hub for art and craft industry. Other than this there are many private companies and organizations that play an important role in creating job opportunities.
There is no dearth of employment opportunities in the city for the skilled candidates. And, at the top of those skill sets, possessing of English fluency is one of the most important skills highly demanded in the market. Wherever you join in the private sector, you will be required to have good English communication skills, both written and oral, for dealing with the clients.
English is one of the most dominant business languages and it has become necessary for the people to speak and work in English if they enter into a global workforce.
Most of the times cross-border business communication is conducted in English.
Yes, it is true. All high paid jobs require good English communication skills.
Most of the content available on the internet is present in English. So knowing English will allow you to access an incredible amount of information.
In India people who know English get more respect and opportunities than who do not know.
English is one of the most widely spoken languages all over the world. If you know English you might have open windows to most of the countries across the world.
You can enjoy Hollywood movies and most prominent English books when you know the language.
You can make new friends from different countries, states, and cultures if you have command over the language.
If you want to go abroad for higher education good knowledge of English can help you to achieve your goals.
Here becomes the role of effective English language very crucial. And the candidates equipped with such communication skills have high chances of getting selected or hired by the top-notch companies. To be succeeded in the business world, you must learn English as a second language. Being bilingual can impress your employers and can open numerous employment options.
Why join our English Speaking programs?
We understand the increasing need for the language, and also aware of the fact that many of our students are from rural areas and studied in non-English medium schools and institutions. When it comes to availing the opportunities in the cities, they always struggle and are left far behind. Therefore, we came up with the ideas of imparting quality English language learning and instil quality skills of English communication among these students.
If you do not want to travel, you can attend our Real-Time classes where you can learn English, ask questions and get the answers to your quarries.
We have tutorials which allow you to use headphones and mic so that you can start the practice of English speaking anywhere anytime.
We offer interesting English content which you can listen. It will help you to build your listening skills.
Our multimedia based English grammar tutorial help the students to learn daily life scenarios in an interactive way.
Often we conduct competitions between students which help them to improve their listening and speaking capabilities. It also helps them to prepare for group discussions and personal interviews for jobs and higher studies.
1. We offer a valuable course taught by industry experts with vast professional experiences.
2. You can learn the language more quickly because we use techniques that are more updated and unique.
3. We offer our students allowed to make important notes in both the electronic and printed form so that they can learn themselves wherever they go.
4. We are equipped with all the essential requirements, from a good infrastructure to richly knowledgeable teaching faculties.
Are you willing to improve your English language & communication skills? If yes, join us today and learn English online.
To locate our presence and to check the distance from your location in Jaipur, just search in Google for English Speaking Classes near me.


Pursue your dream of learning Arabic at Washington Academy of Languages (WAL). For over 40 years, students of all walks of life have chosen WAL to achieve their language learning goals. World travelers and professionals enjoy the flexibility of the evening classes. WAL students enjoy the small classroom settings, classes range between four and fifteen students so you are able to learn in an intimate setting that allows students to practice speaking in class.
At the Washington Academy of Languages, courses are designed to teach Modern Standard Arabic, which represents a blend of the major urban colloquial forms. WAL classes teach reading, writing, listening, and speaking.


text:
Q: How to display Spring MVC form errors for class error I'm familiar with using Spring's <form:errors> tags to display validation errors for object properties, but how do you display an error at the class level?
Here's an example of what I'm talking about:
@ScriptAssert(lang = "javascript",
        script = "_this.isExistingEmployee == true || (_this.phoneNumber != null && _this.address != null)",
        message = "New hires must enter contact information")
public class JobApplicationForm {

    @NotBlank(message = "First Name is required")
    private String firstName;

    @NotBlank(message = "Last Name is required")
    private String lastName;

    @NotNull(message = "Please specify whether you are an existing employee in another area")
    private Boolean isExistingEmployee;

    private String phoneNumber;

    private String address;
}

@ScriptAssert here just confirms that if the applicant has indicated that they are an existing employee they can skip the contact info, but if not they must enter it. When this validation fails, the error is not on a given field but rather is on the class.
Within the form, I can show an error on a field with <form:errors path="firstName"> and I can display all errors (class and field) at once using <form:errors path="*"> but how can I isolate and display class level errors?

A: To show only class-level errors, leave the path empty.
<form:errors path="">

from the Spring docs:

*

*path="*" - displays all errors

*path="lastName" - displays all errors associated with the lastName field

*if path is omitted - object errors only are displayed

ref: http://static.springsource.org/spring/docs/3.2.x/spring-framework-reference/html/view.html#view-jsp-formtaglib-errorstag

redpajama_set_name: RedPajamaStackExchange


Jaipur City Transport Services Ltd has issued notification for 1520 Driver & Conductor Posts vacancies. In this article will find name and number of posts, age, eligibility criteria, application fee, how to apply and last date. So to know more about Jaipur City Transport Services Ltd recruitment 2013 please read this article continue.
Educational Qualification: Candidate should have secondary and for conductor candidates should have secondary pass certificate along with driving license.
The application fee is Rs.600/- for General/OBC and Rs.150/- for others category and should be payable at Depot Manager, Vidya Nagar, Sanganer Depot Jaipur.
All the eligible candidates can apply by filling the given form which can be obtained from the website www.jaipurbus.com after filling the form with all the necessary details send it to Jaipur City Transport Services Limited, Regd. Off. II floor, Old Working Women Hostel, Behind Nehru Place – Lal Kothi Tonk Road, Jaipur on or before January 30, 2013.


Had my eyes checked today. It's been over two years and they keep getting better! No need for corrective lenses except for reading and my old prescription was even too strong for that.
This entry was posted on Wednesday, November 13th, 2013 at 5:37 pm and is filed under Uncategorized.	You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.
4 Responses to Spoiler Alert!
Don't change them Larry, if you have been reading the greens well.


Looking For New Beauty Tips? Check Out These Ideas!
Beauty is the subject of so many aphorisms. Most people have heard that beauty is simply skin deep. To be truly beautiful, someone needs to be not just physically attractive, but also have an attractive personality. People will notice your looks but always remember that a good personality is more important. This article will help you to actualize your inner beauty.
Allow your hair to air dry as frequently as you can in order to protect it from heat damage. All the heat from styling tools can do major damage to your scalp and hair. If you absolutely must blow-dry your hair, you should use your dryer on its lowest heat setting. By doing this, your hair will remain soft and silky.
According to scientific studies, quite a few people find beauty in symmetry. Taking steps to improve the symmetry of your face can make you appear more attractive. You goal is to have both sides of your face be identical to each other.
As they say, beauty is in the eye of the beholder. Beauty is everywhere. For instance, the trees around your neighborhood may be amazingly beautiful or your loved one may constantly strike you as beautiful. Keep your eyes open for potential beauty everywhere you go. Beauty is healthy and heartwarming, and a necessary part of a fulfilling life.
For your eyes, emphasize grays and blues by using copper, apricot and gold eyeshadow colors. Try eyeliner and mascara that is dark brown and has hints of maroon, brick, or deep purple. These shades help your blue eyes stand out.
In conclusion, physical beauty is just skin deep. True beauty means that it is more than simply skin deep. It means that what is on the inside is just as beautiful. The information here lets you stay beautiful by giving you tips that show your beauty off to the world.


text:
(-) Leadership in Society
Threads of Wisdom
By LeAnn Van Cleef-Trimmer | August 07, 2018
In Threads of Wisdom, Caroline Mendez responds to a vacuum that exists for Christian women in business. There is little opportunity for them to engage with other Christian businesswomen about how to use their God-given abilities in the workplace while at the same time giving expression to their faith.
Worthy: Finding Yourself in a World Expecting Someone Else
By Lori Buckle | February 26, 2018
In her book, Worthy: Finding Yourself in a World Expecting Someone Else, Melanie Springer Mock critiques the Christian culture which labels people and puts them into boxes. She then affirms God's heart for every individual by emphasizing how much he loves them, regardless of what the world might think. She shares many experiences from her own life, both painful and positive, that helped challenge her thinking.
Rwandan Women Rising
By Kate Netzler Burch | January 01, 2018
In 1994, 10 percent of Rwanda's population was slaughtered in a mass genocide over a period of 100 days. In the aftermath, Rwandans struggled to secure food and water, find loved ones, and rebuild a sense of security. Into this chaos stepped the women of Rwanda, who defied tradition to take on leadership roles and recovery efforts while dealing with individual and collective trauma and grief.
Equal to Serve: Women and Men in the Church and Home
By Philip Blake | January 30, 1990
I commend this refreshing and scholarly volume to all who are not afraid to open their minds and wills to the scriptures and to the Spirit of God.
By CBE International | April 29, 1988
"We are to concentrate on the inner characteristics of a person, not on his or her gender." So states author Gretchen Gaebelein Hull, a biblical feminist whose new book, Equal To Serve, comes to grips with the controversial social issues of today.
Beyond the Curse: Women Called to Ministry
By Gretchen Gaebelein Hull | July 30, 1991
Subtitled "Women Called to Ministry," Dr. Spencer's book presents a new look at Scripture's description of women's roles. She writes, "Whole dimensions of God, ministry, education and theology are being obscured and ignored if women are not properly trained, then invited, even more so welcomed, to participate as significant and affirmed once they do lead."
Call Me Blessed: The Emerging Christian Woman
By Libbie Brooks | April 29, 1991
Martin provides us with an historical context for the issue of women's roles in the church. She begins by tracing the patterns of male authority in both Old and New Testaments. She also describe some of the more contemporary views on submission of women, and continues with a chapter on how we have actually made God in our image, especially our sexual image.
Women As Global Leaders: Women and Leadership: Research, Theory, and Practice
By Kate Netzler Burch | June 03, 2015
Women As Global Leaders outlines the gaps in current research and points us in a clear direction for future study and consideration. While not overtly religious, this resource is a challenge to CBE readers to take equality to the next level and to consider what true leadership can look like, regardless of gender, on the international stage.
Women and Men: Gender in the Church
By James R. Beck | October 30, 1998
The book's thirteen chapters deal with the many facets of concern that arise when we seek to examine the issue of gender and the church: the theology of gender, gender in the Bible, sex differences, homemaking vs. careers, masculinity and femininity, violence and gender, aging, singleness, racial ramifications of gender, and parenting concerns.

redpajama_set_name: RedPajamaCommonCrawl


Asus has recently announced its new gaming peripherals under the brand STRIX. These new gaming gear includes the Asus Strix DSP gaming headset with audio station, Strix Claw optical gaming mouse, Strix Tactic Pro mechanical gaming keyboard, and Strix Glide Series gaming mouse pads that includes Strix Glide Control and Glide Speed. "STRIX" is actually an ancient Roman and Greek word for owl. For Asus, "Strix means the keenest hearing, the sharpest eyesight and the ability to feel the environment, enabling the player to detect and react to even the slightest movement. Strix means survival on the very edge of instinct. Strix is in gamers' blood, just as it is in ours." Check out the rest of these new gaming peripherals' features and specifications below.
The Asus Strix DSP is a superior multi-platform gaming headset engineered with powerful 60 mm neodymium-magnet drivers, full-size hexagonal ear cushions (130 mm across at the widest point), accompanied by a driver-free plug-and-play audio station that processes native 7.1-channel surround-sound audio. Strix DSP sharpens the wearer's hearing for utterly-convincing audio experiences with unrivalled punch and immersion. Every gunshot and footstep is reproduced with great clarity, bringing the battlefield to life.
Strix DSP's large ear cushions provide a snug fit that remains comfortable for even the longest gameplay sessions. The headset also benefits from a travel-friendly foldable design that allows the ear cups to lay flat.
The USB plug-and-play audio station that's part of the Strix DSP package means gamers enjoy true 3D surround sound with Dolby Headphone and Dolby Pro Logic IIx technologies. Unlike competing models, Strix DSP directly processes native 7.1-channel audio to virtual 7.1 surround sound, so there's no quality-distorting down-mixing by the PC. The result is audio that's truly exhilarating. The audio station also includes highly-effective environmental-noise-cancellation (ENC) technology that filters out up to 90% of external noise for clear in-game communication. A dedicated speaker-output jack and switch means switching from headset to speaker output is a cinch, with no need to mess around with software controls.
Strix DSP adapts its output to suit a variety of genres, including first-person shooter (FPS), racing and action/role-playing games (RPGs). The gamer chooses the relevant audio profiles and Strix DSP boosts the critical audio details – instantly.
Compatible with PCs, Macs, the PlayStation 4 games console and many smartphones and tablets, Strix DSP is one of the most versatile gaming headsets available.
The Asus Strix Claw is the ultimate gaming mouse for first-person shooters, crafted for those who demand killer precision, complete comfort and the competitive advantage – putting everything under control.
The gaming-grade native 5000dpi (dots per inch) optical sensor offers true 1:1 tracking, angle-snap-free movement and flexible DPI controls to ensure that every movement is tracked accurately and reflected instantly. Movement is tracked at speeds of up to 3.32 meters per second (130 inches/sec) with accuracy adjustable by 50dpi increments, so Strix Claw easily configures to match every situation and for tailored gaming precision. There's even a DPI clutch button that lets serious snipers reduce the DPI instantly for super-accurate aiming. An LED indicator shows the current DPI status.
Strix Claw has a total of eight buttons, three of which are independently programmable. The intuitive Strix software is used to assign any key, mouse command or macro, enabling gamers to shift vital commands from the keyboard to Strix Claw – right under the fingertips.
ASUS engineers built Strix Claw with high-quality Japanese-made Omron D2F-01F switches for full-comfort gameplay, no matter how long the session. The design of D2F-01F is adored by the gaming community because it offers more travel than many other switches for smoother clicking actions and great responsiveness, reducing muscle-strain and tingling fingers.
Strix Claw's right-handed ergonomics are perfect for all grip styles, and especially great for the fingertip and claw-style grips that work best in first-person shooters. The streamlined shape provides exceptional comfort and a great grip, allowing gamers to move quickly, precisely and with complete confidence.
Strix Claw is also supremely easy to set up and personalize, with a choice of software or plug-and-play hardware modes. The built-in 64KB memory lets gamers attach and play anywhere, with no installation hassles.
Strix Tactic Pro is an ultra-durable mechanical keyboard engineered with lightning-fast response and a choice of Cherry MX switch types: Black, Blue, Brown or Red. These high-quality switches have a lifecycle of 50-million keystrokes, outperforming conventional keyboards tenfold (10X). They're also fantastically tactile and brilliantly responsive, helping gamers to up their actions per minute (APM) to the max.
Traditional keyboards suffer 'ghosting' that stops some keys being registered, hindering precise control. Strix Tactic Pro employs the highest-specification N-Key Rollover (NKRO) technology over USB to ensure that every key press is registered, regardless of how many keys are held down at once. When the user needs Strix Tactic Pro to behave like a traditional keyboard, the 6-Key Rollover (6KRO) switch does the job instantly.
Strix Tactic Pro is also equipped with 13 dedicated and easy-to-reach macro keys for fast and hassle-free command customization. The user even has the option to reassign F1-F8 as macro keys for a total of 21 one-touch commands. Strix Tactic Pro's on-the-fly macro-recording key allows actions and keystroke sequences to be captured without interrupting gameplay.
In common with Strix Claw, Strix Pro offers a choice of software or plug-and-play hardware modes, enabling advanced personalization and easy installation for gaming on the go.
As the perfect complement for the new Strix gaming-gear, ASUS has designed two high-quality Strix-branded mouse pads: Strix Glide Control and Strix Glide Speed. These product names highlight luxurious upholstering that's tailored for different game styles.
Strix Glide Control is finished with a premium heavy-weave fabric, providing a textured surface for games that require fine control and absolute precision.
Strix Glide Speed is made for gameplay that needs fast, efficient movement, with a fine-weave finish that allows the mouse to glide swiftly across the entire pad with zero hindrance.
Both Strix Glide Control and Glide Speed work brilliantly with either optical or laser mice and are manufactured with fray-resistant edges, which have been tested intensively for better feel, comfort and durability.
As of today, Asus has not disclosed the manufacturer's suggested retail price for the new Strix gaming peripherals. There's no word either when would this product actually hit store shelves. But I'll try to update this post once retail prices become available, and once these gaming gears becomes available to order online.
what a terrible brand name? Strix?


7. विश्व स्वास्थ्य संगठन (डब्ल्यूएचओ) की ताज़ा 'वैश्विक वायु प्रदूषण डेटाबेस रिपोर्ट' के मुताबिक, दुनिया के सर्वाधिक प्रदूषित 15 शहरों की सूची में शीर्ष कितने प्रदूषित शहर भारत के हैं?
विवरण: विश्व स्वास्थ्य संगठन (डब्ल्यूएचओ) की ताज़ा 'वैश्विक वायु प्रदूषण डेटाबेस रिपोर्ट' के मुताबिक, दुनिया के सर्वाधिक प्रदूषित 15 शहरों की सूची में शीर्ष 14 प्रदूषित शहर भारत के हैं.
1. Who has been re-appointed as the Chairman of Public Accounts Committee (PAC)?
2. India revived Track II diplomacy with which nation?
3. Who was appointed as the new coach of Indian men's hockey team?
4. The Supreme Court has directed the centre to take help from experts to look into the colour change of which iconic Indian monument?
5. When was International Labour Day observed?
6. The government of this country has stepped down after election delays.
7. When was the 2018 Ayushman Bharat Diwas celebrated in India?
8. Who was honored with the PC Chandra Puraskaar 2018?
9. Which country will host the multi-nation counter-terrorism exercise "Peace Mission 2018"?
10. Who became the Principal Director General of the Press Information Bureau (PIB)?
11. Which city will host the 15th Pravasi Bharatiya Divas (PBS-2019)?
12. The joint military exercise "Harimau Shakti 2018" started between India and which country?
The leader of Congress party in Lok Sabha, Mallikarjun Kharge has been re-appointed as the Chairman of the 22-member Public Accounts Committee (PAC) of Parliament for its fresh term that started on May 1, 2018. A majority of the members of the parliamentary panel, which is headed by an opposition leader, are from the ruling NDA.
A group of Indian experts had visited Pakistan to discuss all aspects of bilateral ties and revive the Track II diplomacy process with Islamabad amidst the strain in the relationship after a number of terror attacks in India by Pakistan-based outfits. The original Track II initiative, Neemrana Dialogue, received a fresh start with the visit.
Hockey India on May 1, 2018 appointed women's hockey coach Harendra Singh as the chief coach of the Indian men's hockey team, replacing Sjoerd Marijne who will return back to his responsibility as coach of the Indian Women's Hockey Team.
The Supreme Court on May 1, 2018 expressed concern over the changing colour of the iconic Taj Mahal and directed the centre to take urgent steps to restore the pristine glory of the ancient monument at Agra.
The International Labor Day was observed on May 1, 2018. On the occasion, several programs were organized across India to acknowledge the contribution of the laborers in development of the society. The Union Ministry of Labor and Employment also awarded various organizations that are working for the welfare of workers and laborers.
Gabon's government has resigned after the constitutional court dissolved the national Parliament and called for the country's leadership to step down over election delays. The court stated that the powers of the disbanded National Assembly will be transferred to the upper house Senate until elections are held.
As part of Gram Swaraj Abhiyan, Ayushman Bharat Diwas was celebrated across the country on April 29, 2018. During the event, information regarding Ayushman Bharat Scheme was provided to people during health camps organised in rural areas.
Asha Bhosle was honoured with the Lifetime 26th P C Chandra Puraskaar 2018 at the Science City auditorium in Mumbai, Maharashtra on April 29, 2018. The award carries an honorarium of Rs 10 lakh which is tax exempted.
The multi-nation counter-terrorism exercise "Peace Mission" will be held at the Ural mountains of Russia in September 2018, under the framework of Shanghai Cooperation Organization (SCO).
Sitanshu Kar, a 1983-batch Indian Information Service (IIS) officer, became the Principal Director General of the Press Information Bureau (PIB). He succeeded Frank Noronha, who had held the post since 2014.
The 15th Pravasi Bharatiya Divas (PBS-2019) will be held in Varanasi, Uttar Pradesh from January 21 to January 23, 2019. The event will be inaugurated by Prime Minister Narendra Modi and his Mauritian counterpart Pravind Jugnauth.
The first-ever joint Army exercise Harimau Shakti 2018 started between the troops of the Indian and Malaysian armies at Wardieburn Camp in Kuala Lumpur on April 30, 2018.


A rare soulfulness in improvised music is gone.
I remember Mulgrew coming over to my east village apartment to give me a lesson in 1993. He actually came to me ! and as amazing as that was, that's just how Mulgrew was. Ask any musician.
He was wearing a beautiful suit and tie and alot of gold ! He looked like a king…I wasn't sure if it was a dream in a way…i say this in all honesty… my piano was in the gutted downstairs apartment ; just dirt, dust, wood posts, deluge and …a piano. It was like some kind of after-math down there!… Mulgrew never flinched though….Then I asked him how much for the lesson? he said "$20".
I couldn't believe it ! and it was an amazing lesson too….he was so generous with his ideas and time and just played and played….then funnily… every time I asked him, "hey what was THAT you just did "??… he would jokingly say"gimme another $10"!
Everyone says that Mulgrew was always courteous and generous and extremely loyal to his wife and family. From all accounts he was a rock solid human being , he didnt let acclaim change or taint him and he just loved music dearly… that's obvious in the sounds he generated. He said about his own music, "what I play is considered passé" but the fact is, so many of the pianists who get hype today will actually be truly passé in the years to come because Mulgrew's playing created an emotional response that few players today can throw a stick at. Wingspan = Goosebumps. Analyze that.
Mulgrew told me in 1995 that he hadn't really practised in 15 years because he had a family to support and is basically practising on the bandstand whilst touring constantly. I know that after this time he did get back into some more focused practice but what an incredible testimony to the power of the transient musicians life force he was. He lived it and it came through his horn. Great tomes of it.
I have so many fond memories of Mulgrew's playing…and he was just such a gentle spirit. He swung like no one else….he played the blues and he swung the living hell out it and then when he came off the bandstand he would show any audience members and musicians who approached him a true respect …even if you weren't in the band? Now that is rare . So many musicians today seize that moment to reinforce their self proclaimed superiority , especially where the internet provides players with just so much more hype to believe about themselves. In fact, some might say many of them are manufacturing more digital hype than they are music itself. But I suppose Mulgrew did come up in a time where the internet wasn't pimping musicians and he was just sure about who he was and what he did.
I would always go to the late late set at Bradley's so many years back and hear Mulgrew and he would be…shall i say , very warmed up…it was just profound stuff. In the audience would be Monty Alexander, Art Blakey, George Benson, Cecil Taylor and on and on, and they were all there to dig Mulgrew. It was transporting for me. I would leave at 4am and wander around in a daze. I actually have a DAT recording from one of those magical nights. Mulgrew was aware of it because I asked him to explain some of the things he was playing on it. He actually couldn't really explain what it was at one point because he said, "its about a sound, its not about a chord type or a device or a scale, its about a feeling or a color and as you get older you will understand this more"… As a way to express this he told me how Miles Davis would often play a beautiful solo and then ask his sideman "what key are we in"?….And may i say that i sure as hell do understand that now. A kind of spontaneous narrative.
btw, Oscar Peterson "TRACKS". Thank you Mulgrew.
Mulgrew really played different with Tony. He played such full beautiful chords and the way he related to Tony Williams was a sight for sore ears, no one since Herbie Hancock had that kind of connection.
Mulgrew's passing means more than we know. What kind of arcane groove magic has actually gone along with him ? Where can we hear such a thing again? I feel a void that I wasn't expecting for many reasons but mainly because Mulgrew was both a bright star , a warm earthling and just a musicians musician.


text:
Q: Why doesn't Resource.Id have a definition for my Button? <?xml version="1.0" encoding="utf-8"?>
<RelativeLayout     xmlns:android="http://schemas.android.com/apk/res/android"
android:layout_width="match_parent"
android:layout_height="match_parent"
android:orientation="vertical"
android:padding="10dp">
<ImageButton
    android:id="@+id/imageButton2"
    android:layout_width="250dp"
    android:layout_height="120dp"
    android:layout_alignParentBottom="true"
    android:layout_centerHorizontal="true"
    android:src="@drawable/play5evenlighter"
    android:background="@null"
    android:scaleType="centerInside" />
<ImageView
    android:id="@+id/munchTitle"
    android:src="@drawable/titlelighternodonut"
    android:layout_width="300dp"
    android:layout_height="90dp"
    android:layout_centerHorizontal="true"
    android:paddingTop="10dp" />
<ImageButton
    android:id="@+id/donutButton1"
    android:src="@drawable/strawdonut2"
    android:layout_width="115dp"
    android:layout_height="100dp"
    android:background="@null"
    android:scaleType="fitXY"
    android:layout_marginTop="120dp"
        />
</RelativeLayout>

This is where the error appears, in the MainActivity.cs
ImageButton donutButton1 = FindViewById<ImageButton>(Resource.Id.donutButton1);

The error says that Munch2.Resource.Id does not contain a definition for donutButton1...
In the xml above, you can see that I have set the android:id="@+id/donutButton1" but the error still persist.
I think the error may have to do with the fact that I made the imageButton from scratch in the xml file as opposed to dragging it out from the toolbox in the designer.
Any help is appreciated! Thanks!


Now is the time to relax, renew, and reconnect with loved ones in your own backyard retreat. We provide top-of-the-line, quality hot tubs and spas. Our commitment to our customers' complete satisfaction is guaranteed!
We design our spas for the very best massage experience. Out innovative jets are designed for specific muscle groups, and deliver powerful streams of water that you can customize to your desired pressure.
If you want to transorm tension into rejuvenation every time you step into your hot tub, look no further than Caldera Spas. We design for comfort, performance and style!
Freeflow Spas plug into any standard 110v outlet. Simply add water, plug in your hot tub and enjoy. If you rent, our lightweight spas can be taken with you wherever you go.
Experience the ultimate in quality, luxury and relaxation in spas and hot tubs. Artesian Spas is an award winning American manufacturer of spas and hot tubs.


Wireless sensor network management API is tool for wireless sensor application developers. API provides an easy, fast and resource efficient interfaces (web / Java) to create, manage and confiqure / optimitze of wireless sensor system. API is implemented on Contiki OS as open source code.


text:
Prevalence and impact of Streptococcus pneumoniae in adult cystic fibrosis patients: a retrospective chart review and capsular serotyping study
Christina S Thornton1,
Erin L Brown1,
Joenel Alcantara1,
Harvey R Rabin1, 2 and
Michael D Parkins1, 2Email author
© Thornton et al.; licensee BioMed Central. 2015
Received: 10 November 2014
Accepted: 16 April 2015
Published: 2 May 2015
Cystic fibrosis (CF) is a genetic disease characterized by complex polymicrobial communities within the lower respiratory tract. S. pneumoniae, while a well-defined pathogen in the general population, has rarely been identified in CF. Furthermore, prevalence studies on Pneumococcus in CF have predominantly focused on the infant and pediatric populations, and outcome data is lacking.
Through a review of our comprehensive clinical and microbiologic database from a single adult CF center in Canada from 1978–2013 we sought to determine the incidence, prevalence, serotype and clinical impact of Pneumococcus in adults with CF.
Only fifteen of 318 adult CF patients (5%) were ever found to have transient Pneumococcus colonization, and none developed persistent infection although length of carriage varied. As all isolates were stored, capsular serotyping could be performed using a multiplex PCR panel. Capsular serotyping revealed a varied distribution of several serotypes within these isolates. Lung function testing at time of incident Pneumococcus isolation was compared with values before and after isolation and showed no significant reduction in spirometry values, nor was there an increased need for rescue antibacterial therapy.
Within our center, incident Pneumococcus infection is neither common, associated with a disproportionate clinical deterioration nor results in chronic infection.
Pneumococcus
Pulmonary exacerbation
Streptococcus pneumoniae is an important respiratory pathogen that has been implicated in several respiratory diseases including otitis media, pneumonia and sinusitis [1]. The prevalence of pneumococcal nasal-pharyngeal asymptomatic colonization in the healthy adult population has been estimated to be at 20-50% [2]. Isolation of Pneumococcus in CF has been predominantly studied in infants and young children [1,3]. Several studies have addressed the pathogenic potential of Pneumococcus in CF and have found increased biofilm formation, increased antibiotic resistance [4] and the isolation of this species during acute exacerbation [1]. Studies on prevalence within adult CF patients are limited; with one group finding ten percent of CF patients had cultivatable isolates from routine sputum samples during periods of clinical stability when specifically sought using enhanced culture techniques [2]. The impact of isolating Pneumococcus from sputum on short and long term CF disease progression, however, is unknown.
The objectives of this study were to do a retrospective longitudinal study of adult CF patients to assess Pneumococcus incidence and prevalence as determined by routine culture practices. Clinical impact of infection was evaluated by comparing requirement for antibacterial therapy and changes in lung function before and after infection. Finally, phenotypic characterization was performed including antibiotic susceptibility and capsular serotypes of the pneumococci isolates to assess distribution within this cohort of adult CF patients.
A retrospective audit was performed on the Adult Cystic Fibrosis Clinic of Southern Alberta, Canada's comprehensive sputum biobank. This prospectively collected and maintained biobank includes frozen stock of every bacterial isolate ever identified, from every clinical encounter between 1978–2013. Inclusion of patients into this study was dependent on a diagnosis of CF, and the confirmation of positive culture(s) of S. pneumoniae from any sputum sample done routinely at quarterly clinic visits and during periods of exacerbation. Corresponding clinical information was collected through detailed chart review including baseline demographic details, and the clinical course before and following isolation of Pneumococcus. Differences for percent predicted FEV1 (forced expiratory volume in one second) and FVC (functional vital capacity) lung function tests were assessed using the Student's unpaired t-test. This study complies with the University of Calgary Conjoint Health Research Ethics Board (CHREB E-23087).
Sputum samples collected in real time were mixed with equal volumes of dithiothreitol (DTT, Sputolysin, EMD Millipore Billerica, MA) and vigorously vortexed. Samples were then serial diluted in DTT to a final dilution of 10−5. Samples diluted at 10−3 and 10−5 were then plated on routine CF media including: Columbia Blood Agar (CBA), MacConkey (MAC), Chocolate Agar (CHOC), Mannitol Salt Agar (MSA) and in the later years Burkholderia cepacia agar. S. pneumoniae were identified through standard approaches including flat, centrally depressed alpha-hemolytic colonies on CBA/CHOC, which were Gram positive diplococcoid, catalase-negative, Optochin sensitive (generally) and bile salt soluble. Isolates were frozen in skim milk stocks and maintained indefinitely at −80°C [5,6].
In 2014, S. pneumoniae isolates cataloged at any time point from the biobank were then targeted and subbed out from frozen stock and incubated in 5% CO2 at 37°C for 48–72 hours and their identity re-confirmed. DNA was extracted from isolates using boiling preparation where colonies were re-suspended in 50 ul of ddH20, boiled for 15 minutes and then centrifuged at 13,000 rpm for 10 minutes. Capsular serotyping PCR was performed following the protocol described by Jourdain, et al. to screen for 30 classical S. pneumoniae colonizing serotypes [7]. A positive control of genomic DNA from S. pneumoniae strain ATCC 6303 was used alongside the internal cps loci within the multiplex PCR for comparison. Each PCR reaction was run on two separate occasions to ensure accuracy. Susceptibility testing was performed in real time to penicillin and those samples recovered had susceptibility testing to other common anti-Pneumococcal agents as well as those antibiotics commonly used in CF, using the Kirby-Bauer method as per the Clinical and Laboratory Standards Institute (CLSI) [8].
During the 34 years assessed only 27 S. pneumoniae isolates were identified from the 33,166 (0.08%) bacterial isolates collected from expectorated sputum samples from 318 patients in our biobank (Table 1). All isolates were cultured from sputum in real time at colony forming units (CFU) ranging from 104-107/ml (Table 2). No invasive isolates were identified. These were from 15 patients; 10 males and 5 females with a median age of 28.0 (IQR (inter-quartile range) 23, 30) years at time of first isolation. 11/15 of the patients were pancreatic insufficient and 67% 10/15 also had a major CF co-morbidity. Co-morbidities included CF related diabetes (3/15), arthropathy (3/15), liver and biliary problems (12/15) and sinonasal manifestations (5/15). Interestingly, one-third of the patients were chronic smokers. The median (IQR) for baseline FEV1 was 75.5% predicted (62.5, 105.5) and for FVC was 82.6% predicted (71.5, 112.5). Baseline chronic microbial pathogens included P. aeruginosa (12/15), S. aureus (7/12), H. influenzae (4/15) and Burkholderia cepacia complex (2/15). 8/15 of the patients had co-infection with two or more of the principal pathogens listed above. None of the samples were from patients who had previously undergone lung transplantation.
Adult cystic fibrosis patient demographics from those with isolated Pneumococcus cultures
Agea
BMIb
FVC (L)c(% predicted)
FEV1(L)d(% predicted)
Pancreatic sufficient
Smoker status
CF Co-morbidities
Chronic pathogense
M1101K
PA, SA, HI, Bcc
F508del
PA, SA
PA, Bcc
CFRD, Sinus
D110H
3659delC
394delTT
G551D
CFRD
Arthropathy, Sinus
SA, HI
CFRD, Arthropathy
PA, HI
aAge at time of first isolation of S. pneumoniae.
bBMI: body mass index.
cFVC: forced volume capacity, defined as an average of two values in the year preceding time of pneumococcus isolation.
dFEV1: forced expiratory volume, defined as an average of two values in the year preceding time of pneumococcus isolation.
ePA: P. aeruginosa, SA: S. aureus, HI: Haemophilus influenzae, Bcc: Burkholderia cepacia complex; chronicity as defined by repeated isolation of pathogen on at least 50% of cultures over the prior two years.
Pneumococcus isolates from 1986–2013 in adult cystic fibrosis patients
Patienta
Date of isolation
Capsular serotypeb
Influenza vaccined
Decreased PFTe
Need for Anti-bioticsf
Co-Isolated organisms (CFU)g
Antibiotic susceptibilityc
LVX
N/Ah
PA non-muc (107), PA muc (105) Bcc (106), HI (105)
6A/B
PA non-muc (105), PA muc (107) SA (108)
SA (108)
SA (108), HI (108)
9A/V
PA non-muc (107), PA muc (107), Bcc (105), EC (105)
33A/F
PA non-muc (106), PA muc (107)
PA muc (105)
CA (107)
PA non-muc (106), SA (106), CA (105), Asp (105)
7B/C
PA muc (106), SA (104)
PA muc (107), CA (104)
PA non-muc (106), PA muc (107), EC (105)
Cfc (104), HI (106)
HI (106)
SA (106), PA non-muc (104), PA muc (104), HI (106)
PA non-muc (104), PA muc (106), SA (106)
aRefer to Table 1.
bCapsular serotyping done on recoverable isolates.
cAntibiotic definitions: Penicillin = PEN, Levofloxacin = LVX, Azithromycin = AZM, Clindamycin = CLI, S = Sensitive, R = Resistant
dInfluenza vaccine prior to pneumococcus isolation.
eReduced PFT: pulmonary function tests; as defined by a reduction in reduction in FEV1 by >10% at time of visit compared to baseline FEV1 levels.
fRequirement for antibiotics at time of pneumococcus presentation.
gPA: P. aeruginosa, SA: S. aureus, HI: Haemophilus influenzae, Bcc: Burkholderia cepacia complex, Asp: Aspergillus. sp, EC: E. coli, CA: Candida albicans, Cfc: Citrobacter freundii complex, OF: oropharyngeal flora.
hN/A: Not available for serotyping or antibiotic susceptibility testing.
iNT: non-typeable serotype but with positive cps internal PCR product control.
Twelve patients were at a routine clinic visit at the time of sputum collection and subsequent Pneumococcus isolation. Samples from three patients were taken at time of hospitalization or during self-reported acute reductions in health. Only two patients had chest imaging done at time of sputum collection, and both showed pulmonary infiltrates. Six patients had recurrent Pneumococcus isolation, which was discontinuous over a period of time ranging for several months, although none developed chronic infection. One patient had two separate infection periods where different strains of Pneumococcus were cultured a decade apart. Of note, 10 patients did report flu-like symptoms prior to time of Pneumococcus isolation (ranging from one week to five weeks) that consisted of dyspnea (7/10), lethargy (100%), increased sputum production (100%), hemoptysis (20%), and weight loss (40%) from prior clinic visit. Several of the patients with flu-like symptoms also had confirmed viral titers preceding or at time of S. pneumoniae isolation and were obtained during periods of acute exacerbation (patient 2 with influenza A, patient 3 with influenza B and patient 10 with influenza A and parainfluenza). No difference was observed in the requirement for acute antibacterial therapies during the clinics from which Pneumococcus was isolated to either those visits occurring in either the year prior to its isolation [10/27 (37%) vs. 14/45 (31%), relative risk (RR) 1.19 (CI 0.62-2.30), p = 0.62] or following [10/27 (37%) vs. 21/45(46%), RR 0.8 (0.44-1.41), p = 0.47].
Of the 27 isolates, 18 were recoverable from frozen stocks and their serotype confirmed (Table 2). Capsular serotypes were performed on the 18 isolates with no predominance observed, rather a distribution of ten different serotypes. Interestingly, three isolates could not be serotyped using multiplex PCR for the thirty most common Pneumococcus serotypes [7] but did display the internal cps control confirming Pneumococcus identification. Among the patients with repeated isolates of Pneumococcus, the serotypes identified were not homogenous and were varied even within the same patient. Two patients (8 and 11) had the same Pneumococcus serotype of 23 F over a one month period and 23B over a three month period. Despite extensive chart review, Pneumococcus vaccination records could only be found for one patient (9) with a capsular serotype (23A) that was not included with the 23-valent Pneumococcus vaccine.
Detailed chart review observed that only two isolates were resistant to penicillin upon original testing (7.7%). Amongst the 18 recoverable isolates, additional antibiotic susceptibility testing was performed (Table 2). Four strains (22%) were resistant to azithromycin, but none to clindamycin nor was resistance inducible. Four strains were resistant to levofloxacin (22%), and whilst CLSI breakpoints do not exist for ciprofloxacin, considerably smaller zones of clearance exist suggesting its activity is much more limited (20.5 mm (IQR 18–23) vs 18.5 mm (IQR 14–21), p = 0.07. In addition beta-lactams commonly used in CF with anti-pseudomonal activity including meropenem (47 mm IQR 42–50) and piperacillin-tazobactam (49.5 mm IQR 43–51), showed larger zones of clearing than ceftazidime (34 mm IQR 20–38) although established breakpoints similarly do not exist, p = <0.001. Tobramycin, with no appreciable Gram positive activity beyond Staphylococi, showed very high levels of resistance with zones (<6 mm).
Lung function in the CF patients was compared at time of Pneumococcus isolation with values at the preceding and following two routine clinics to determine if either an acute deterioration or change in disease trajectory occurred as a result of infection (Figure 1). No differences were noted in either percent predicted FEV1 or FVC through periods of pneumococcal infection.
Pulmonary function (FEV1 and FVC) among CF patients with Pneumococcus. Spirometery was compared from each patient at each time of Pneumococcal isolation with the values from two clinics immediately preceding and following this visit to assess for impact on lung function. No changes in FEV1 were apparent at the time of pneumococcus infection compared to prior (p = 0.6665) or subsequent clinic visits (p = 0.4783). Furthermore, no differences in FVC were observed at time of pneumococcus colonization relative to prior values (p = 0.3354) or follow-up (p = 0.5385). Overall, there appeared to be no significant impact on lung function.
Pneumococcus has been well established as a principle respiratory tract pathogen, predominantly in the pediatric and elderly populations. However, CF patients are unique owing to a state of chronic colonization and infection alongside a dysregulated host immune response [9]. Despite this, Pneumococcus is uncommonly reported in CF, and little/no information exists on its prevalence and impact in adult CF patients [2]. Herein we identified that Pneumococcus comprised less than 0.1% of bacterial isolates from a 34-year comprehensive CF biobank where Pneumococcus was identified using classical microbiology protocols, affecting <5% of patients. Furthermore, there were no documented cases of invasive pneumococcal disease, such meningitis and blood stream infection, during this time. The extreme uncommon nature of Pneumococcus in this population was unexpected and may reflect how CF microbiology protocols have been developed and biased to identify classical pathogens such as S. aureus, and P. aeruginosa.
In CF, the traditional clinical picture has been of chronic lower respiratory tract infections with principal pathogens including P. aeruginosa, S. aureus, and Burkholderia cepacia complex. Recently, the polymicrobial nature of CF has been demonstrated to comprise of a variety of microbial species that include Rothia, Prevotella, Klebsiella and members of the Streptococcus genus [5]. While several members of the streptococci, such as S. anginosus group, have been implicated in CF disease progression [6], other viridans group streptococci (VGS) including S. pneumoniae have not traditionally been considered as primary CF pathogens. However, when specifically sought, using a combination of selective agars such as Mitis–Salivarius agar and high density sampling low levels of Pneumococcus can be identified in up to 10% of sputum samples [2]. In this light it is apparent that traditional approaches to CF sputum culture are likely to be insensitive to the identification of Pneumococcus, particularly at low density.
As a case series and not a controlled study, limited information can be inferred regarding risk factors for Pneumococcus isolation detected by traditional CF protocols. However, 4/15 patients had chronic infection with H. influenzae, which is much higher than the standard colonization frequency observed in the adult CF population (<10%) [10]. A high prevalence of smokers similarly was observed, which may explain the disproportionate identification of H. influenzae, a common colonizers pathogen in smokers [11]. Furthermore, a large proportion of colonization events were preceded by viral upper respiratory tract infection, which in the general population result in increased colonization potential of these Pneumococcus [12].
The clinical impact of Pneumococcus in CF is poorly understood. We sought specifically to determine if either an acute, or long-term impact followed detection of Pneumococcus from a CF sputum sample using classical CF protocols. We did not identify any statistical difference in lung function at time of isolation compared to the two clinic visits occurring before or after pneumococcal isolation as measured by FEV1 and FVC. Furthermore, patients with Pneumococcus in their sputum were no more likely to require antibiotics than during clinic visits occurring in the two years before or after. Finally, no patient went on to develop persistent chronic infection, suggesting that eradication strategies advocated for pathogens such as P. aeruginosa, MRSA are not warranted [13,14].
Antibiotic resistance is a growing concern within CF patients, given the longer life expectancy and increased demand on antibiotic use. S. pneumoniae is readily competent, allowing horizontal gene transfer between microorganisms for several antibiotic resistance markers including pbp1a, pbp2, mefE, ermAM and tetM [15]. The presence of S. pneumoniae may not be overtly pathogenic in a traditional sense within the CF patient, but may be contributing to the greater antibiotic resistome of the patient by dissemination of antibiotic resistance markers. Antibiotic resistance has been observed in other streptococci species in CF, in particular the S. anginosus group, azithromycin (54.9%), erythromycin (52.9%) and clindamycin (49.0%) [16]. While susceptibility data in our study suggests limited resistance to several classes of antibiotics, the Pneumococcal resistance rates have been reported to be on the rise by other groups with 73% to penicillin, 42% to erythromycin, 58% to tetracycline and 67% to trimethoprim-sulfamethoxazole [1]. The discrepancy in Pneumococcus susceptibility values in CF may be attributed to therapeutic management at various sites, global trends of antibiotic use and resistance, and exposure to agents from the pediatric to adult clinics.
Serotyping in this study identified ten different capsular serotypes with no predominant pattern observed. Another work assessing Pneumococcus population structure found the most frequent serotypes in CF were 23 F, 19 F, 6A and 6B [1]. Geographical location and time period may in part affect serotype distribution, as has been described with several antibiotic resistance mechanisms in Pneumococcus [17]. Interestingly, the 23-valent-Pneumococcus vaccine does not cover serotypes 38 and 23A, which were identified in several of our patients. The variety of serotypes within the same patient suggests, given the short time frame between some repeated cultures, likely several strains of pneumococci were present but with only a single isolate recognized as opposed to strain displacement within a single patient. Indeed, co-colonization has been observed with surprising frequency [18]. Coinciding with this, strain displacement of serotypes may be occurring over prolonged periods of time. Furthermore, several isolates could not be serotyped using a strategy to detect the most common capsular serotypes [7], which may suggest acquisition of atypical pneumococci that require further investigation.
The question as to why Pneumococcus was observed in such low prevalence is of particular interest. This may in part be due to in sensitive differentiation from other VGS using standard practice of bile solubility, optochin susceptibility and colony morphology [19]. Furthermore, the use of primarily quantitative microbiology may also result in reduced identification of low quantity organisms within cultures. As well, Pneumococcus colonization is typically higher in young children and then declines with age with a peak in the elderly age group – a group not represented in an adult CF clinic [20]. The median predicted survival of CF patients in Canada is current 50.9 years [21] and as this population ages, Pneumococcal disease may become an issue for older CF patients [22]. More provocatively, however, it may be that chronic infection with classical CF respiratory pathogens and the resultant competition for space and nutrients in the lower airways is protective against extrinsic pathogens such as S. pneumoniae.
Current recommendations in CF care involve pneumococcus vaccination with either the 23-valent polysaccharide or, 7 or 13-valent conjugate vaccine [23,24]. The recommendations for these guidelines are derived from those with other respiratory diseases. As such, the need for prevention and treatment of Pneumococcus in CF warrants further investigation as work from this study has shown both low incidence of culture and recovery of patients without further clinical decline, spontaneous clearance and lack of chronic infection. Furthermore, the 23-valent vaccine does not reduce rates of pneumonia but rather is effective in preventing invasive disease such as meningitis and bacteremia [25]. The role of vaccination in CF patients is one that warrants further exploration and perhaps recommendations based on CF specific data as opposed to adaption of recommendations for those with other types of chronic lung disease.
This study has several notable limitations. Few patients were included, and patient data was also limited for those patients who are lost to follow-up or deceased. As we focused on short-term outcomes in this small population we may have been insensitive to longer-term effects. Other clinical parameters may be used in the future to assess if Pneumococcus isolation in CF patients affects disease progression such as number of exacerbations per year, number of hospitalizations, changes in antibiotic regimen and quality of life index scores [26]. As this was a retrospective study evaluating the isolation of S. pneumoniae using traditional CF microbiology protocols, it is likely insensitive to the identification of isolates present at low levels. Indeed, prospective studies using semi-selective medias and in depth culturing would be required to determine the prevalence of low level colonization, and how this might impact clinical progression. Furthermore, it may be necessary to adjunct phenotypic culturing with molecular methods as this has been shown to improve efficacy of identification [27].
In this study, we found Pneumococcus was infrequently identified in the respiratory tract of adults with CF. Furthermore, when Pneumococcus was identified, no apparent adverse impact on outcomes was noted with respect to requirement for rescue antibiotic therapy or changes in lung function.
FEV1:
Columbia blood agar
CHOC:
Chocolate agar
DNA:
Deoxyribonucleic acid
CFU:
Colony forming unit
CLSI:
Clinical and Laboratory Standards Institute
NT:
Non-typable
P. aeruginosa
S. aureus
H. influenzae
Burkholderia cepacia complex
PFT:
Pulmonary function test
PEN:
LVX:
AZM:
CLI:
MDP is a recipient of research funding from Cystic Fibrosis Canada. This project was unfunded.
CST, ELB and JA have no conflicts to report. HRR and MDP have served in the past five years on advisory boards for Novartis and Gilead, and have received research support from Gilead Sciences.
CST was responsible for collection and analysis of all patient related data, assisted ELB in capsular serotyping and developed the manuscript. JA, HRR and MDP were responsible for the conception of the project, supervision of the collection and analysis of patient and microbiologic data, and assisted with writing and revising the manuscript. All authors read and approved the final manuscript.
Department of Microbiology, Immunology and Infectious Diseases, Calgary, Canada
Department of Medicine, Adult Cystic Fibrosis Clinic, Calgary, Canada
del Campo R, Morosini MI, de la Pedrosa EG, Fenoll A, Munoz-Almagro C, Maiz L, et al. Population structure, antimicrobial resistance, and mutation frequencies of Streptococcus pneumoniae isolates from cystic fibrosis patients. J Clin Microbiol. 2005;43(5):2207–14.View ArticlePubMedPubMed CentralGoogle Scholar
Maeda Y, Elborn JS, Parkins MD, Reihill J, Goldsmith CE, Coulter WA, et al. Population structure and characterization of viridans group streptococci (VGS) including Streptococcus pneumoniae isolated from adult patients with cystic fibrosis (CF). J Cyst Fibros. 2011;10(2):133–9.View ArticlePubMedGoogle Scholar
Hoiby N. Epidemiological investigations of the respiratory tract bacteriology in patients with cystic fibrosis. Acta Pathol Microbiol Scand B: Microbiol Immunol. 1974;82(4):541–50.Google Scholar
Garcia-Castillo M, Morosini MI, Valverde A, Almaraz F, Baquero F, Canton R, et al. Differences in biofilm development and antibiotic susceptibility among Streptococcus pneumoniae isolates from cystic fibrosis samples and blood cultures. J Antimicrob Chemother. 2007;59(2):301–4.View ArticlePubMedGoogle Scholar
Sibley CD, Grinwis ME, Field TR, Eshaghurshan CS, Faria MM, Dowd SE, et al. Culture enriched molecular profiling of the cystic fibrosis airway microbiome. PLoS One. 2011;6(7):e22702.View ArticlePubMedPubMed CentralGoogle Scholar
Sibley CD, Parkins MD, Rabin HR, Duan K, Norgaard JC, Surette MG. A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients. Proc Natl Acad Sci U S A. 2008;105(39):15070–5.View ArticlePubMedPubMed CentralGoogle Scholar
Jourdain S, Dreze PA, Vandeven J, Verhaegen J, Van Melderen L, Smeesters PR. Sequential multiplex PCR assay for determining capsular serotypes of colonizing S. pneumoniae. BMC Infect Dis. 2011;11:100.View ArticlePubMedPubMed CentralGoogle Scholar
CLSI. Performance Standards for Antimicrobial Disk Susceptibility Tests;Approved Standard. In: CLSI document M02-A10. 19th ed. Wayne, PA: Clinical and Laboratory Standards Institute; 2009.Google Scholar
Sibley CD, Rabin H, Surette MG. Cystic fibrosis: a polymicrobial infectious disease. Future Microbiol. 2006;1(1):53–61.View ArticlePubMedGoogle Scholar
Lipuma JJ. The changing microbial epidemiology in cystic fibrosis. Clin Microbiol Rev. 2010;23(2):299–323.View ArticlePubMedPubMed CentralGoogle Scholar
Morris A, Beck JM, Schloss PD, Campbell TB, Crothers K, Curtis JL, et al. Comparison of the respiratory microbiome in healthy nonsmokers and smokers. Am J Respir Crit Care Med. 2013;187(10):1067–75.View ArticlePubMedPubMed CentralGoogle Scholar
McCullers JA. Insights into the interaction between influenza virus and pneumococcus. Clin Microbiol Rev. 2006;19(3):571–82.View ArticlePubMedPubMed CentralGoogle Scholar
Ratjen F, Munck A, Kho P, Angyalosi G, Group ES. Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis: the ELITE trial. Thorax. 2010;65(4):286–91.View ArticlePubMedGoogle Scholar
Macfarlane M, Leavy A, McCaughan J, Fair R, Reid AJ. Successful decolonization of methicillin-resistant Staphylococcus aureus in paediatric patients with cystic fibrosis (CF) using a three-step protocol. J Hosp Infect. 2007;65(3):231–6.View ArticlePubMedGoogle Scholar
Schrag SJB B, Dowell S. Resistant pneumococcal infections: the burden of disease and challenges in monitoring and controlling antimicrobial resistance, Centers for Disease Control and Prevention. Atlanta, GA, United States of America: World Health Organization; 2001.Google Scholar
Grinwis ME, Sibley CD, Parkins MD, Eshaghurshan CS, Rabin HR, Surette MG. Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. Antimicrob Agents Chemother. 2010;54(7):2823–9.View ArticlePubMedPubMed CentralGoogle Scholar
Leclercq R, Courvalin P. Resistance to macrolides and related antibiotics in Streptococcus pneumoniae. Antimicrob Agents Chemother. 2002;46(9):2727–34.View ArticlePubMedPubMed CentralGoogle Scholar
Brugger SD, Frey P, Aebi S, Hinds J, Muhlemann K. Multiple colonization with S. pneumoniae before and after introduction of the seven-valent conjugated pneumococcal polysaccharide vaccine. PLoS One. 2010;5(7):e11638.View ArticlePubMedPubMed CentralGoogle Scholar
Richter SS, Heilmann KP, Dohrn CL, Riahi F, Beekmann SE, Doern GV. Accuracy of phenotypic methods for identification of Streptococcus pneumoniae isolates included in surveillance programs. J Clin Microbiol. 2008;46(7):2184–8.View ArticlePubMedPubMed CentralGoogle Scholar
Robinson KA, Baughman W, Rothrock G, Barrett NL, Pass M, Lexau C, et al. Epidemiology of invasive Streptococcus pneumoniae infections in the United States, 1995–1998: Opportunities for prevention in the conjugate vaccine era. JAMA. 2001;285(13):1729–35.View ArticlePubMedGoogle Scholar
Registry CCF: 2013 Annual Report. 2013.Google Scholar
Mackenzie GA, Leach AJ, Carapetis JR, Fisher J, Morris PS. Epidemiology of nasopharyngeal carriage of respiratory bacterial pathogens in children and adults: cross-sectional surveys in a population with high rates of pneumococcal disease. BMC Infect Dis. 2010;10:304.View ArticlePubMedPubMed CentralGoogle Scholar
Malfroot A, Adam G, Ciofu O, Doring G, Knoop C, Lang AB, et al. Immunisation in the current management of cystic fibrosis patients. J Cyst Fibros. 2005;4(2):77–87.View ArticlePubMedGoogle Scholar
Pimentel De Araujo F, D'Ambrosio F, Camilli R, Fiscarelli E, Di Bonaventura G, Baldassarri L, et al. Characterization of Streptococcus pneumoniae clones from paediatric patients with cystic fibrosis. J Med Microbiol. 2014;63(Pt 12):1704–15.View ArticlePubMedGoogle Scholar
Melegaro A, Edmunds WJ. The 23-valent pneumococcal polysaccharide vaccine. Part I. Efficacy of PPV in the elderly: a comparison of meta-analyses. Eur J Epidemiol. 2004;19(4):353–63.View ArticlePubMedGoogle Scholar
VanDevanter DR, Konstan MW. Outcome measures for clinical trials assessing treatment of cystic fibrosis lung disease. Clin Investig. 2012;2(2):163–75.View ArticleGoogle Scholar
Maeda Y, Goldsmith CE, Coulter WA, Mason C, Dooley JS, Lowery CJ, et al. Comparasion of five gene loci (rnpB, 16S rRNA, 16S-23S rRNA, sodA and dnaJ) to aid the molecular identification of viridans-group streptococci and pneumococci. Br J Biomed Sci. 2011;68(4):190–6.View ArticlePubMedGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.


text:
We were having a long midweek dinner at Le Pichet in Seattle, a sort of anticipatory wake for the Seattle P-I, where my friend Tom had worked as a reporter for 20-some years. Tom's pretty crusty and tends to brush even the most irksome things off with a joke.
But being a fifty-something journalist facing a post-newspaper era in a town awash in laid-off reporters, reality had started to sink in. Even so, referring to the demise of his employer and the economic times in general, at one point Tom gestured outside to First Avenue and said, "But this is no crisis. Somalia has a crisis. We don't."
With sufficient perspective, of course, that's true. Relatively speaking, Seattle has no crisis in spite of losing a daily newspaper, Washington has no crisis in spite of a $9 billion shortfall, and Washington State University has no crisis in spite of facing its worst budget cuts since the Depression. But that kind of perspective can admittedly be difficult to maintain in such times as these.
In the 1933–35 biennium, the state legislature hit Washington State College with a 36.5-percent budget cut. But that was following earlier cuts. Reading through the early 1930s minutes of the WSC regents meetings, it's tough to follow and tabulate the continuous economic blows not just to WSC, but to the University of Washington and the "normal schools," also. It's actually a fascinating, if depressing, narrative. Unfortunately, it does not offer the balm of historical perspective that one might hope for. For we live in different times.
In 1932, a meeting of higher education representatives decided to meet legislative cuts with salary cuts, applied as equitably as possible. Those making $3,600 and up would take a 10-percent cut. Those making $2,600 and up would take a seven-percent cut. Those making $2,100 to $2,500 would take a five-percent cut. And those making less than $2,100 would suffer no cut.
President Holland, who earned $12,000 a year, had his salary reduced to $10,800. Ida Lou Anderson, mentor of Edward R. Murrow, continued to earn $1,600 for her nine-month appointment. (Only two people at WSC making more than $2,100 did not take a salary cut: football coach O.E. "Babe" Hollingbery, who made $8,000 a year, and assistant football coach and baseball coach A.B. "Buck" Bailey, who made $3,750 a year.)
By the fall of 1932, Holland and the Regents realized they would have to make further, more drastic, cuts. Those making $1,200–2,100 would take five-percent cuts. Campus janitors, who made $97.50 a month, took a $5 cut.
The following spring, 1933, everyone was hit with additional salary cuts with totals ranging from 15 to 25 percent. (Hollingbery and Bailey had mysteriously disappeared from the roster, if not from campus.)
What might we learn from our history? Maybe nothing. But it might be fruitful to ask how Holland managed to hold the campus together in spite of such hardship. How did he retain such eminent faculty members as Claudius Johnson, Hannah Aase, Herbert Kimbrough, and Edward Gaines in spite of slashing their salaries by 25 percent? Actually, the relevant question is more likely, "how did he maintain any morale whatsoever?"
For the Depression offered the retention solution. They had nowhere better to go.
Tim Steury, Editor


list stone crusher companies india - High quality crushers .
Stone Crusher Machine Company In India - . Used stone crusher,mining equipment for sale in . Mining machine,crusher,quarry equipment are widely used for crushing in ore mineral, gold, concrete plant, aggregate. Contact Supplier Stone Crusher Machine Price In India .
sand stone importers,indian sand stone import companies. business classified of sand stone importers browse india b2b marketplace of sand stone import companies. limestone importers in canada, process crusher, mining .
best crusher making company in india - What is the price of stone crusher - Quora. As one of leading stone crusher manufacturer and exporters located in China, Great Wall Company put emphasis on stone .
stone crushing companies india manufacturer in Shanghai, China. stone crushing companies india is manufactured from Shanghai Xuanshi,We are a professional . India Stone Crusher, India Stone Crusher .
Home» stone crushing swot analysis of company in india Dev Bootcamp Reviews | Course Report Dev Bootcamp is an 18-week coding bootcamp with campuses .
stone crusher company in india stone crusher company in india, Comprehensive Industry Document Stone Crushers - CPCB ENVIS. India, the Stone Crushing Industry sector is estimated to have an annual turnover of .. crusher are owned by bigger construction companies like L&T, Dodsal.
Feb 13, 2016 · China mobile crusher manufacturer,quarry stone crusher for Quarry Crusher. grinding mills 12 x 14 ton hrs table; api 13a barite fob in india; crushing and screening plant 80 .
list of crusher companies in india-[crusher and mill] Stone Crusher plant in india, machine price for sale. The limestone crusing process, has been started production for nearly one years ( since May,), and it is. Free Quote. concrete breaker machine price in india - amroninternational.
STONE CRUSHER Manufacturer, Supplier, Exporter, Dealer in India Get Details of STONE CRUSHER Manufacturers, STONE CRUSHER Suppliers, .STONE CRUSHER Wholesalers, STONE CRUSHER Companies. .Sand Brick Machines, Concrete Mixers, Stone Crushers, Portable Jaw Crusher.
list of stone crusher companies in india - protable plant. stone crusher manufacturer, supplier, exporter, dealer in indiaget details of stone crusher manufacturers, stone crusher each listing includes .
Find Stone Crusher manufacturers, suppliers, wholesalers, dealers, distributors in Rajasthan India - Stone Crusher verified companies listings from Rajasthan with . Read More mobile stone crusher manufacturers in india for sale,used . stone crusher suppliers and exporters from India.
financials of stone crushing companies in india, most marble companies in India and abroad generally specialize inKalingastone is manufactured and the fourth one is the marble crushing plant.
stone crusher equipment india Care Calls Systems Ltd stone crushing machine manufacturers, suppliers amp exporters. these stone crushing machine manufacturing companies provide high quality gidc, nr.kiran motors .


text:
Home Costa Rica Legal TopicsCorporate Law The Costa Rica Government is Dissolving More Companies
The Costa Rica Government is Dissolving More Companies
by rpetersen October 3, 2021
The Costa Rica government recently published in the official Gazette ( La Gaceta) a list of more than 500 companies that pursuant to Law No. 9428, were automatically administratively dissolved for failure to pay the annual company tax for three consecutive years.
The following is the exact wording of the publication:
"ADMINISTRATIVE BOARD OF THE NATIONAL REGISTRY REGISTRY OF LEGAL ENTITIES
Pursuant to the provisions of Article 7 of the Corporate Tax Law, No. 9428, the Registry of Legal Entities informs that the following entities: (…) Which are processed under file number DPJ-DI-001-2021, entities that according to the information sent by the General Directorate of Taxation of the Ministry of Finance through certification DGT-DR-CER-001-2021, are delinquent with the payment of the tax on legal entities for three, or more, consecutive periods, reason for which they are dissolved as of right, as established in Article 7 of the Law of Tax on Legal Entities, No. 9428. Pursuant to the provisions of Article 207 of the Commercial Code, within thirty business days, the interested parties may present the considerations of the case before the competent jurisdictional authority. Once the term established by law has elapsed, for notice of interested parties, the cancellation of the registration of the entities and the respective annotation of the preferential lien in the respective Registry will be made, so that they may proceed accordingly."
As of the date of publication, a term of 30 business days was conferred so that the interested parties could present the justification they considered necessary before the competent jurisdictional authority. Upon expiration of the term, the registration of the entities was cancelled and liens on the assets registered in the name of the dissolved companies were recorded.
It is important to remember that according to Article 7 of Law 9428: "In the event of dissolution of the commercial companies, individual limited liability companies or the branch of a foreign company, and the respective cancellation of the registration, the Tax Administration is empowered to continue the collection procedures or establish them against the last officially registered partners, who will be jointly and severally liable for the payment of this tax".
If you see your company on this list then it is time for you to take action otherwise you will need to initiate a formal company liquidation process to recover the company assets.
This is the current list of companies on the list
COSTA RICA INACTIVE COMPANY TAX FILINGS EXTENDED
Costa Rica Company Filing Obligations for 2022
Inactive Companies Must File A Tax Return by March 15, 2022
The Mandatory Shareholder/Beneficial Owner Filing for Costa…
Is it Worthwhile to have a Costa Rica Holding Company Anymore?
Filing deadline for Inactive Companies Extended – Again...
Inactive Companies Must File A Tax Return by...
Is it Worthwhile to have a Costa Rica...
How much is the Costa Rica Company Tax...
The Mandatory Shareholder/Beneficial Owner Filing for Costa Rican...
Can you hold a virtual shareholder meeting for...


Unfortunately, professional review of the Thing-in-Itself game is not yet ready. This game is on the list and will be reviewed in the nearest feature. Meanwhile, you can find more from the official description below.
Ted and Molly are together. Ted feels a connection to Molly wherever he looks.
But, how do they both really see the relationship? See each other?
Thing-in-Itself is an interactive short story about the struggles of understanding another human being. Using Immanuel Kants concept as a framework, it leads the player through stages of a relationship, exploring how perceptions may clash and surroundings can alter.
With an average walkthrough time of 15 minutes, Thing-in-Itself is not a game in a traditional sense it doesnt have win or lose conditions and doesnt present challenge to the player.
With this project, Party for Introverts attempts to establish a connection between the mediums of game and short story, reworking the possibilities when narrative and interactivity merge.
We publish only honest game reviews based on real game experience. If you think that our Thing-in-Itself game review is not full enough and you have something to add - write to us. We looking for talented authors to make our reviews better!
There's not a lot of questions about Thing-in-Itself. Ask insistently in the comments so you can make it frequent!
© 2017 Party for Introverts. All rights reserved.


text:
Home Art Photographer George Rodriguez's "Double Vision" Reveals Two Versions of L.A.—and Beyond
"Boyle Heights, 1970"
George Rodriguez
Photographer George Rodriguez's "Double Vision" Reveals Two Versions of L.A.—and Beyond
The legendary photographer's incredible range is on display in an exhibit and a new book
Gwynedd Stuart
On the sun-dappled walls of the Lodge in East Hollywood, two versions of L.A. come to life. A photo of Frank Sinatra embracing an aging Lucille Ball shares a wall with an image of a man being hustled past a Boyle Heights taco stand by a police officer in riot gear. Further down the wall, the members of N.W.A. pose in front of a backdrop spray painted with circa-1990 hip-hop lingo: Yo! Fresh! And in an adjacent room, labor icon Cesar Chavez poses in front of a Robert Kennedy campaign poster a year after the presidential candidate's 1968 assassination.
What the images all have in common is their creator, George Rodriguez. A native of South Central, the octogenarian spent his career occupying and photographing two very different but equally iconic versions of Los Angeles. By day he was an operative of the entertainment industry, photographing album covers and Hollywood events. On his own time, he'd drive to the Eastside and cover the walkouts and marches taking place as part of the Chicano Moratorium.
"Living in South Central and then being at Hollywood premieres—it was like two different worlds," he recalls. "My photographic life has really taken me in a lot of different directions. I feel fortunate for one thing—to be born and live in L.A. is a big plus."
Besides the show at the Lodge (which is up till Saturday, July 14), Rodriguez compiled his photos into a book, Double Vision: The Photography of George Rodriguez, edited by MacArthur Fellow Josh Kun. According to Rodriguez, he and Kun conceived of the project while Kun was curating a show for the Grammy Museum. "Initially I had the idea to do a book, but my thought was that it would be on the Mexican-American experience and the Chicano Movement, but then Josh…came to my studio to look at some rock 'n' roll stuff. [People] see the things on the walls and they're kind of surprised that I worked in so many areas, rock 'n' roll and television and motion pictures and civil rights, you know." Rather than focus exclusively on his civil rights photography, Double Vision embraces the disparate ways Rodriguez applied his unique eye.
"Oak Valley, Louisiana, 1970"
The exhibit at the Lodge, much like the book, largely focuses on the work Rodriguez did in and around L.A., with one notable exception. Titled "Oak Valley, Louisiana, 1970," a photo of an African American man flanked by ancient oak trees and, in the distance, what looks like an antebellum plantation house speaks to Rodriguez's range as an artist and documenter of history beyond L.A.'s confines. "I was working on a television special called America (originally was to be called America or Bust)," Rodriguez recalls. "I believe that title [was] a bit too controversial. A TV crew of two trucks and a bus started at Arlington National Cemetery and we made our way back West to get a feel of the country." He adds, "The gentleman in the photo was the assistant to the foreman of the plantation. [He] was so gracious, polite, respectful, helpful—a man of the South. Overwhelmingly humble. I have never forgotten him."
Over the course of his many years behind the lens, Rodriguez has seen many things change—he specifically points to the resurgence of DTLA—and other things, sadly, stay the same, particularly in terms of Latinx people's fight against discrimination. "I think of my great grandma," he says. "If she had been born in L.A. 16 years earlier, she would have been born in Mexico. I think this will all pass and everybody will kind of settle down."
He adds, "I don't dwell on it. I'm very fortunate to have made my life in photography and to have spent it all here in Los Angeles."
Double Vision at the Lodge, 1024 N. Western Ave., East Hollywood, closes Sat., July 14; Rodriguez and Kun will appear for a conversation about the book on Wed., July 18 at Skylight Books, 1818 N. Vermont Ave., Los Feliz.
RELATED: The Book That Made Me Want to Stay in L.A.
Stay up to date with everything you need to know about L.A. by following us on Facebook and Instagram.
Chicano Moratorium
Previous articleExperience a Taste of Everything ROW DTLA
Next articleA Brush Fire Broke Out In Griffith Park and the Observatory Was Evacuated
To the Front Is Smashing the Patriarchy of Music Photography One Pop-Up Gallery at a Time
The Best Exhibits at Museums and Galleries in L.A. in July
Hip-Hop History Comes to Life in a Series of 120 Amazing Photos


Scott Fraser Training provide ground based chainsaw training courses, tree climbing courses and LOLER inspection courses amongst many more - all from our City & Guilds Approved Assessment Centre in Kent.
We provide a personal, flexible approach to your chainsaw training and machinery training requirements - whether you are a novice starting your career, developing skills or refreshing existing ones.
Scott Fraser Training is a City & Guilds NPTC Assessment Centre - we meet their strict Quality Assurance requirements. Book your ground based or aerial based chainsaw assessment, climbing assessment or LOLER inspection course here.
If you need more information about any of our courses please get in touch!