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Paul personally trained those whom he sent out.
Have you been in any of your leader's training sessions or demonstrated a godly lifestyle!
Paul taught his students and pushed them into studying the scriptures and learning the ways of God.
One of the stories I love is the relationship which Paul and Timothy had, when it came to a student learning from their teacher.
Timothy was accountable to Paul and submitted to his leadership and guidance, because he knew Paul's lifestyle and that he was a person of great wisdom of the things of the Spirit and the Word!
Timothy recognized that Paul operated beyond the spheres of his natural education and that Paul stood for righteousness.
Timothy listened and submitted to his instructor's learning about character, loyalty, being honorable and how to operate in integrity. He not only received from Paul, but he served Paul faithfully!
Have you served your leader faithfully?


The Abundance Book: John Randolph Price:.
Hay House, Inc. | Author | John Randolph.
Biography of John Randolph Price, author of the best selling books The Angels Within Us, and The Abundance Book, plus many other books.
John Randolph Price Biography and Book.


Cheer on your Air Force Falcons in this Top of the World Memory 1Fit flex hat! Top off your game day outfit with this hat and make sure everyone knows you're rooting for the Air Force Falcons. It features quality Air Force Falcons embroidery and Memory Fit foam that adjusts to your cap size for the perfect fit each time!
Air_Force_Falcons_Top_of_the_World_Memory_1Fit_Flex_Hat_-_Royal_Blue http://images.fanatics.com/lf http://dmimages.ff.p10/chains/1778160.txt false We are unable to customize this item with the text you have entered. Please try a different entry again. Your current entry cannot be processed due to guidelines for past and present player names. Please create a new entry.


Floral gardens of the valley come alive to drape the women of freedom into the most luxurious wrap with a saree crafted in the classic black and white. The saree flows freely with its blended crepe base which gets embroidered in undaunted caresses of Aari Embroidery spanning over the pallu magnificently. Wear the saree to special events and let it speak for your refined taste of ethnic dressing.


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text:
Primordial Meditations
PRIMORDIAL MEDITATIONS by Claudio Vera and Martin Pelenur
September 17th - October 24th, 2015
Opening Reception: Thursday, September 17th, 6-8PM
Artemisa Gallery is pleased to announce Primordial Meditations, an exhibition featuring two Uruguayan artists Claudio Vera and Martin Pelenur. The show will be on view from September 17th to October 24th, 2015.
It is embedded in human nature to be thoughtful and innovative for survival. Collectively, a dialogue surrounding this concept is excavated from Vera's and Pelenur's parallel bodies of work, to raise thought provoking questions that are inherent to humanity's progression on earth, as well as, within society. How can humanity move forward in connection with the land, and how does one's consciousness allow this process to unfold? Such primordial concerns with existence have continued through ancient times into contemporary civilization. To investigate Vera and Pelenur in this vein brings to light the association of physical and cerebral conditions, which are key to the balancing act that humanity must perform throughout time.
Claudio Vera's newest body of work is intensely contemporary and sensual, evolving seamlessly from his most recent series of wooden sculptures. Vera's works on paper are created through a similar, physically intensive process of carving blocks of wood; however, instead of sculpting the artist deconstructs flat wooden surfaces and turns them into topographies, territories, physical maps, where we can wander endlessly. Vera has consciously altered his medium of choice - a conceptual reflection on deliberate transformation that exists in the structures of nature, the cosmos, and the ideas of contemporary science explored by humankind.
Vera's roots are linked to the Latin American tradition of the "School of the South," as the artist studied for many years under one of Joaquín Torres García's most famous pupils, Julio Alpuy. Like his teacher, Vera's work embraces and dissolves boundaries, revealing an intimate relation between mankind and the natural world, derived from a deep understanding of organic structures and systems.
Martin Pelenur's newest body of work manifests itself through his use of paint and other synthetic mediums on paper: some forms are painted dense and heavy on the surface, thick with pigment, yet others take on fragile and crystalline structures that seem to emulate the delicate nature of inner thought. Still more, a final group of works are made with commercial packaging tape arranged in lattice form on paper. Each variation of Pelenur's work shows a progressive creation of simple forms via the human mind.
In 2006, the artist started his own self-promoted "Pelenur Scholarship," based out of his studio Ciudad Vieja - translated as "Old City." Pelenur's approach to scholarship is untraditional, and his actions in doing so become an extension of his ongoing practice as an artist who explicitly devotes himself to the research of painterly materials and their collaboration with the "mental drift" that is an integral part of the evolution of society. For Pelenur, the act of painting is an experiment in thought and the inner human discourse that is methodic and repetitive when studied in depth. Even more so, perhaps his superficially manufactured scholarship is reflected in his preferred use of synthetic materials, as opposed to organic, when exploring the progressive nature of human thought.
Claudio Vera is an Uruguayan artists who was born in 1975, and studied at the Instituto Escuela Nacional de Bellas Artes in Montevideo, Uruguay. Vera has exhibited his work in prominent galleries in the United States, Colombia, Uruguay, Peru, and most recently in Canada. Vera currently lives and works between Spain, Italy and France.
Martin Pelenur was born 1977 in Uruguay, and studied at the Contemporary Art Foundation in Montevideo. Pelenur's work has been exhibited across Uruguay, Argentina, Berlin, and the United States. Pelenur was the recipient of multiple awards, including the 2010 Goethe Instituted Scholarship in Berlin; 2011 Paul Cezanne Award at the Alliance Francoise in Montevideo' and the 2012 14th FEFCA Scholarship from the Uruguayan Ministry of Culture and Education. The year 2015 is one of Pelenur's most pivotal yet, with upcoming solo exhibitions at the AMA Museum in Washington, and the Sayago & Pardon Collection in California. The artist currently lives and works in La Barra, Maldonado, Uruguay.

redpajama_set_name: RedPajamaCommonCrawl


Brazil is currently the seventh-largest producer of cocoa in the world, with approximately 200,000 tons per year. But in the 1980s, before witch's broom disease eradicated 75% of cocoa plants in Bahia State and the global market price declined, Brazil produced more than 430,000 tons of cocoa.
Today, Brazil has approximately 70,000 producers who grow cocoa on the almost 700,000 hectares. At least 80% of those farmers are small or medium-sized, holding less than 10 hectares on average. Most of those farmers don't have the financial resources and technical support to increase their productivity, especially those that produce shade-grown cocoa in natural forests. Therefore, one of Brazil's challenges is to engage and help thousands of small farmers access technology and private and public finance in order to increase cocoa productivity and improve the livelihoods of thousands of farmers and families.
Now that the crisis is over, farmers and the cocoa industry want to increase cocoa production and productivity and help Brazil become a world leader in sustainable cocoa. The country's national Association of the Cocoa Processing Industry (AIPC), which purchases more than 95% of cocoa in Brazil, has made a commitment to double cocoa production in the next 10 years. At the same time, the World Cocoa Foundation (WCF) has founded CocoaAction, which hopes to create a voluntary industry-wide strategy in strong partnership with the public sector for the future of Brazilian cocoa with sustainability at its core.
After the Initiative 20×20 investor round table held in São Paulo in 2018, WRI Brasil heard loud and clear that Brazilian cocoa farmers needed more information and better examples if they wanted to ramp up production. The team identified two projects in Peru that could inspire and help Brazil develop and implement small and medium cocoa agroforestry outfits, both featured on initiative20x20.org, the Tambopata-Bahuaja REDD+ and Agroforestry project in Madre de Dios and the Peru Cocoa Alliance.
In collaboration with AIPC and WCF and financial partner Althelia funds, a Brazilian delegation visited these two model sites during the week of November 25-30. During the first part of the trip the delegation visited several cocoa agroforestry systems and silviculture projects that used native species in the regions of Pucallpa and Aguaytia.
Those projects are just a sample of an ambitious program led by the Peru Cocoa Alliance, a private-public alliance with the participation of the main actors of the cocoa supply in Peru such as farmers, industry, exporters, service providers, finance institutions, etc. The Alliance supports 20,000 farmers that produce organic and/or high-quality cocoa and agroforestry systems on 53,000 hectares and count on the support of USAID and is led by the Palladium group. One of the goals of the program is to double cocoa productivity from 600 kg/hectare to 1,200 kg/hectare. The quality of the technical assistance provided by the Alliance's more than 70 advisors is key to its success and sustainability.
The second part of the exchange was hosted by AIDER, a local NGO and Initiative 20×20 partner, in the National Reserve of Tambopata and the National Park of Bahuaja-Sonene in Madre de Dios, which covers 570,000 hectares of natural forests. The main goal of the project is to provide economic alternatives for the communities that live in the buffer zone surrounding the Reserve and to reduce deforestation in the protected areas.
The first phase of the project provided support to 343 families and 1,258 hectares of cocoa agroforestry production on degraded lands in the buffer zone. The goal of the project is to expand to 4,000 hectares of cocoa agroforestry and engage 400 farming families by 2021. The Brazilian delegation was very impressed with the design of the cocoa agroforestry production systems and the quality of the management. WRI Brasil is confident that this REDD+ project experience and investment model can be replicated in Brazil.
The exchange was not only successful because of what WRI Brasil and its partners had learned and what the delegation can take back home. It also inspired the Brazilian delegation to think about how it could advise Peruvian farmers. Initiative 20×20 and its partners look forward to encouraging similar knowledge exchanges in the future.


Here we have a magnificent smoking box and station that will easily fill the needs of the most avid smoking enthusiasts.
This wooden combo box comes equipped with an insert box for easy use and more importantly a stylish metal lock and key. This guarantees security for any possessions placed in the box.
The 3x5 insert box is built with a removable inner sifter with a quality monofilament mesh.
Ryot nicely decorates the 6x8 box with the iconic Ryot logo carved into the interior of the lid.


Recently there's been talk of a caravan of immigrants marching towards the United States, principally focused on Mexico and Central America. But there's also another caravan, this one at work in the biopharma business: the long term migration of science and technology professionals into the US-based biopharma ecosystem.
Biotech leaders have been vocal in the past about DACA and other immigration issues (here). Seven biotechs showed the impact of immigration on their workforce last fall with these fantastic photos (here) – showing the huge percentage of their teams that have direct connection with immigration.
At Atlas, we certainly seek out the best and the brightest in our industry – and recruit from all over. Boston is a global aggregator of talent, as I've described in the past, and certainly helps us add gravity to our recruiting process. But we've never paused to take a look at the practical impact of immigration on our firm, so I decided to do a quick analysis of our CEOs.
Atlas is clearly indifferent to nationality – we, like all venture investors and company-builders, just want the best CEOs possible. We recruit folks from all over.
As this illustration shows (with each flag representing a CEO), of the 26 active CEOs in our US-based biotech companies, 50% hail from other nationalities at birth. A few of those have since become naturalized US citizens. The UK and Canada are the big two.
As an individual partner at Atlas, I get to work closely with a number of CEOs: amazingly, of the 11 boards I serve on, 8 have CEOs who are immigrants. That's nearly 75%.
Biotech startups, like most, are teams that go well beyond the CEO role; the leadership ranks of our biotech portfolio also reflect this global talent pool. Immigrants are a huge part of these science-led stories, as with many biotechs. It's critical to the success of our industry. From the biotech corner office to the lab tech, science truly knows no borders.
With Washington unable to move forward a bipartisan solution to immigration reform, we're hurting ourselves. With the failure to fix DACA, we're leaving Dreamers behind – losing out on this important and talented group. And with the H-1B visa program under attack, we risk losing another 85K foreign professionals annually. This program in particular is critical for STEM professions like biopharma and the life sciences more generally.
MassBio is putting on an important event next week to talk through some of these immigration issues (see link here). As distracting as it is to our day jobs, we all need to make sure we focus on ensuring immigration reform supports continued US leadership in biopharma.
This entry was posted in Boston Cluster, Pharma industry, Talent. Bookmark the permalink.


OK, so this is really October 29. I did the last one at night and this blog has never figured out the right time.
Now, on with Psalm 34. As I read through this psalm I am amazed that early theologians and church leaders wanted to make strong lines of delineation between the covenant made with the Hebrew people and the writings that came out of the reform movement in Judaism begun by Jesus of Nazareth. This psalm has the essential concepts of Christian thought that are important in my faith life. As with many of the psalms, this one begins with praise.
Wouldn't this be a wonderful way to begin everyday and to encourage others in their day. To tell them if things aren't going well (always a possibility) that we can rejoice in God's faithfulness.
I love these types of psalms because they sound so much like my life. Again the psalmist is telling us to never hide our feelings from God and that calling out to God in times of difficulty is a good thing. Obviously, it is not unusual for God's people to get into trouble and need God to find hope. I particularly like the imagine in this next verse.
I remember a friend who once talked to me about the importance is visualization. She said during tough times, or when you were searching for healing – mental or physical – visualization could be a great tool. So, next time you are feeling low imagine being surrounded by a circle of God's angels. Now angels is not something that is easy for me to visualize, but I can imagine good friends and the monks of my favorite monastery stand around me praying for me if life gets hard. I remember when my Dad was in the hospital after his heart attack and going recovery from a very difficult surgery I posted my status on Facebook. I remember it as being very simple, something like, "in the hospital praying for my Dad". I got comments from many friends saying they were praying for me too. So, although I am not get with angels – this experience I can get on board with.
The psalmist continues with some good advice on being a follower of God.
The advice from the psalmist has no real difference from this teachings of Jesus. Of course, it is from this texts that Jesus learned and grew in God's grace. I like this psalm because as much as there is comfort for those who run to God for guidance and for shelter, there is a separation for those who place themselves in opposition to God's ways.
The final verses of the psalm speak again of God's rescue and care. These verses remind me particularly of the hopes of the Christian way.
A thousand years before Jesus was done, and two thousand years before the advent of atonement theology; the psalmist articulates God's redemption of those who are enslaved. There is nothing new under the sun. For me it is good to know that God has been understood as a God of saving grace since human beings have been describing what it is to be in relationship with God.
Blessings and peace upon this wet day brought to you by SANDY and climate change.
"1-3 Good people, cheer God!
Right-living people sound best when praising.
As I think about the "earth being drenched in God's affectionate satisfaction", I think about the rains the SANDY will bring. I don't think those who are in the midst of the storm are understanding our drenching this way. But, what would it be like if we did? What if we took the days that we are going to be immobilized by the storm and found ways to study, praise and open ourselves to God's presence?
Well, the psalmist continues to talk about God's creation of all that is and then considers human beings.
I pray in this day, you are feeling God loving you and knowing that it is the real power in our life to make your life whole and holy.
Hello friends, sorry for my absence for a few days. Of course the big reason is laziness, the other reason is "Downton Abbey". My parents and I have watched the first two seasons, supplied by the public library, and we are ready for the third season to begin January 2013.
So on with Psalms, and 32 is wonderful direction for mental and spiritual health.
This is one of my favorite things about my faith. That each new morning I can wake up and talk to God about anything and begin again with new hope and new possibilities. I don't have to be bound by my mistakes or past stupidity, but I can work out a new plan of who I want to become with God's grace. The important dynamic the psalmist explains is that we have to be ready to tell God everything.
my words became daylong groans.
In this section of the psalm, the writer expresses how detrimental it is to hold our pain, or doubts, or hurts inside. It is said that, what we hid inside of us has power over us." So, the psalmist expresses this mental health axiom in this part of the psalm.
I have felt this sense of freedom, have you? I have often said that guilt is the most useless of emotions. I believe it is good to realize when we have done something wrong; hurt someone by our actions, but we have to move on. If we can learn from our mistakes, then guilt is more than useless; it holds us in a bad place, rather than moving us on to a good place.
we'll be on high ground, untouched.
As the psalmist says, prayer is the path. Prayer is what will keep us safe and sane when the difficulties of life press in on us. I love the imagine of who God is in verse 7. It is this kind of relationship with God that keeps us spiritually healthy.
every time they turn around.
Psalm 31 bring another song of encouragement. The writer is leaning on God, in hopes that God will continue to find a path of life and hope for the psalmist. I like all of the psalm so I will include all of it here and write commentary in between the paragraphs.
" I run to you, God; I run for dear life.
Take me seriously this time!
your high cliff aerie a place of safety.
be my true mountain guide.
I want to hide in you.
I've put my life in your hands.
I like that the write is so straight forward with God. There is complete trust in God's faithful to care for the writer's needs and protect and guide them. I think this intimate relationship with God is what brings hope even in difficult circumstances.
but gave me room to breathe.
I'm in deep, deep trouble again.
turned my bones to powder.
I'm ridiculed by the neighbors.
they cross the street to avoid me.
how to ruin me for good.
as they drift down to hell.
I love the reference to silly religions. When I was a teen I had a book called, "How to be a Christian without being religious. The emphasis was on a personal relationship with the living God, rather than focusing on all the human rules created in most religions. Of course, it was also the '70s and the 'Jesus Movement' was in full swing. Yet, the idea of finding "The Way" has always appealed to me more than following the institutional church. I know this will be no surprise to those who know me.
I also like this psalm because the writer talks about getting themselves into trouble one more time. I always identify with someone who finds themselves in the midst of problems and seeks God to find peace and relief from those 'heckle' the followers of God.
to escape an unkind world.
His love is the wonder of the world.
those arrogant enough to go it alone.
24 Be brave. Be strong. Don't give up.
Expect God to get here soon.
As I have been reading through and writing on the psalms, I have enjoyed the deep emotion of the psalmist. I feel the writer has striped bare and opened themselves to God and each time they have found blessings. I was listening to songs on the radio that conveyed this kind of passion as well. For the first audience of the psalms, were these songs/psalms the 'soundtrack of their lives'? Just wondering.
I am amazed at how little I knew the psalm before beginning this blogging thing. I love Psalm 30 and it reminds me of important parts of my journey of faith.
you didn't let my foes gloat.
and you put me together.
The phrase that Eguene Peterson paraphrases 'pulled me out of the grave'. is translated, 'redeemed my life from the pit' in the New Revised Standard Version of the bible. I tell you this in order to tell you of an experience that has stayed with me for a couple of decades. I was working on an Emmaus weekend – this is a Spiritual Life Retreat for adults – the youth version is called Chrysalis. One of the clergy women who was working on the weekend with me asked me why I talked so freely about my faith in God. My response was, "because he redeemed my life from the pit." It was a psalm phrase I had learned recently, and it fit my life perfectly.
My life was a mess of teenage intensity and isolation. When I committed my life to God it began a journey that has given my life meaning and direction and peace. So, this psalm speaks to me very personally. So. . .
"All you saints! Sing your hearts out to God!
Thank him to his face!
a lifetime there is only love.
and decked me with wildflowers.
I can't keep quiet about you.
I add my Amen. I pray you find this same joy in your life.
Yesterday was Dad's 86th birthday and today we are celebrating with a special dinner and lemon meringue pie. So, it is a great day to look at Psalm 29. A psalm of praise.
in awe before God's visible power.
Dress your best to honor him!
God, across the flood waters.
God topples the northern cedars.
The high ridges jump like wild kid goats.
7-8 God's thunder spits fire.
He makes the desert of Kadesh shake.
A wild dance, whirling; the pelting rain strips their branches.
from which he rules the world.
11 God makes his people strong.
God gives his people peace.
I decided to include all of the psalm because it isn't very long and all the images are intertwined. The writer uses the experience of nature, particularly that of water to see the power of God. There was a day almost 20 years ago when I stood on the porch when a really strong storm was approaching the area. First the winds came through bending the branches of the trees and rattling the leaves. Then the rain came down in sheets and quickly flooded the street. It was amazing the change the occurred in a short time. I can imagine the psalmist seeing that kind of storm arise and feeling the power of God within it.
For me, the question is what language or what image would I use to describe the wonder of God? Where do you see the wonder, or power, or grace of God in your day? What song can you sing to tell about the nature of God to others? For me, it is always a great day when I can see the beauty of God's creative nature. Today it was the multi-colored leaves of wonderful oak tree. This time of year always reminds me of the diversity and extravagant beauty of God.
I hope you find something to praise today.
I know myself fairly well and I know that I tend to only look at the bright side – I am a self-avowed Pollyanna. I kinda like the approach to life, but I know that I do not always see the negative side of people, or notice when people are working at things that are not good or healthy for themselves or other people. However, the psalmist does not have this problem.
when I call you, God.
The psalmist is calling out to God because they want to make sure God know they are not like others who are deceitful in their lives.
then moonlight for the Devil.
for how bad they've been.
Then cap it with a huge bonus.
I think we probably all know people who say one thing to us and then later say something completely different; maybe even speaking badly about us. Or people seem to work at causing problems wherever they go. The psalmist is asking God to pay back those who have worked "in the Devil's workshop." Now as I confessed, I rarely think about those who are working it ways that are not helpful to other or are destructive in what they say or do. But in one way I think this psalm is correct in that these people will find themselves destroyed. Personally, I don't think God does this, but they do it to themselves. It is my experience that people who work from negative energy, trying to destroy others, will eventually have the pain they cause fall back on themselves. I don't think we need to look for God to smash them to smithereens, they are doing enough destruction that it will fall back on them.
For me, I try to remember just to talk to God about it – kinda like the psalmist. And in all circumstances to praise God and try to look through each situation from a God view.
I've thrown my lot in with him.
and shouting and singing my thanks to him.


text:
Cartoonists.net - Famous Cartoonists | List of the Top Well-Known …
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The people on this list are from different countries, but what they all have in common is that they're all renowned cartoonists. The list of popular cartoon artists include Dr. Seuss, Bill Watterson, Charles M. Schulz, Matt Groening, and more. Featuring political cartoonists, cartoon creators, and great American cartoonists, this list has them all!
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What education do I need to become a cartoonist?
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What are the responsibilities for a cartoonist?
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Crypto regulation echoed in the World Economic Forum
By Samvidha Sharma 20 January 2023, 01:54 PM
The World Economic Forum (WEF) summit in Davos has witnessed representatives from nations and institutions across the globe discuss topics of importance.
Sources reveal that several global central banks and regulators have utilized the ongoing summit to call for an urgent rollout of basic regulations targeting cryptocurrencies like Bitcoin. The bankers at the summit opined that the evolving nature of the cryptocurrency sector and the speculative nature of digital assets means that regulators need to step in and enact the necessary laws.
The group at the summit led by Tharman Shanmugaratnam, a senior minister of Singapore, along with Francois Villeroy de Galhau, governing council member at the European Central Bank, and Colm Kelleher, chairman of UBS Group AG, an investment firm, agreed that the recent events in the crypto sector call for regulations.
According to Villeroy de Galhau, the recent events in the market, including the collapse of cryptocurrency exchange FTX and the performance of money market funds, can be linked to what he called "non-banks."
The greatest challenge today is non-banks. All of them have one common feature — they are all linked with non-banks. And here, we lag behind. It's more difficult because it's a very evolving landscape. So we should rush to some urgent non-bank regulation starting with cryptos.
In that context, Kelleher suggested that assets in the crypto space should be able to meet the "basic hurdle" of anti-money laundering. In this case, he noted that due to the inability of most cryptocurrency products to meet clear anti-money laundering checks, companies in the industry could not justify selling a currently constituted product.
Further, Kelleher expressed his bullish stance regarding blockchain technology, stating it is unstoppable. When asked about his clients, he said that UBS clients might be interested in exploring crypto products, but the organization wishes to wait for regulation before taking a step. He said:
"We are looking for a regulatory framework that will allow us to accommodate that for our clients."
Notably, despite calling for regulations, Shanmugaratnam warned that with the advent of regulations, the sector, which he believes to be inherently speculative and slightly crazy, would get legitimized. Nonetheless, he supported the regulation for the industry to cover loopholes that bad actors could exploit to promote money laundering.
He also said:
Some things are very clear: whether it's crypto or traditional finance, you've got to regulate for things like money laundering.
Interestingly, the recent growth of cryptocurrencies and digital assets has found a significant place amid the discussions at the Davos summit, with delegates challenged to lead the industry's regulation.
In the summit, the vice prime minister of Ukraine opined that he wishes to see the nation become the best jurisdiction for the crypto asset and plans to receive his salary in the country's central bank digital currency (CBDC), i.e., E-Hryvnia.
Crypto regulation has been a much-highlighted topic in recent times. Regulators from across the globe have highlighted the necessity of efficient and clear regulation for the sector. A few days back, Caroline Pham, Commissioner of the Commodity Futures Trading Commission (CFTC), called on the regulators to provide clear guidance on crypto assets this year.


Description The home residence of Mr. and Mrs. John Scudday Herbert, located at 611 Lynnbrook Road, in Nashville, Tennessee. This was their family residence from October 1932 through July 1971. These digital reproductions were scanned from the scrapbook of Mrs. Frank A. Wilk (Alva Herbert Wilk). 1 digital photograph.


Are you using Outlook and have lots of .msg files which you want to export MSG format Email Outlook to PDF? Then get the advanced MSG to PDF Conversion tool that supports to export batch MSG files to PDF at one. With the help of MSG format Email Outlook to PDF tool, you can simply export Outlook MSG email to PDF with metadata, formatting, hyperlinks, etc. If you want to know about how to export MSG format Email Outlook to PDF then download free demo of the tool which can export 25 MSG emails to PDF without any cost. So solve your all issues and easily export MSG format Email Outlook to PDF without any trouble.


text:
Project MC2 Review
Smart is the new cool for this tween spy show.
Project MC2, Netflix's spy show aimed at tweens, is absolutely ridiculous - cheesy and over-the-top in a Power Rangers kind of way. But beneath that camp, it's got a heart and a fistful of good messages about friendship, teamwork and empowerment.
The show features four girls who each have a STEM background. Camryn does gadgets, Bryden does hacking, Adrienne does chemistry ("culinary chemistry", to be precise), and McKeyla is a generalist who also happens to be a spy. The girls end up working for NOV8, a spy organization run by women. One of them is McKeyla's mom (played by Danica McKellar, mathematics author and advocate). They go on absurd adventures, like protecting a famous prince who's going on a space tour or stopping an anarchist who's messing with all the tech in town.
Girl power is obviously a main theme, with the friends supporting each other and learning to work together as a team. There's a little mother/daughter dynamic between McKeyla and her mom, but it's more of a background thread. Many of the antagonists are women as well.
For a show whose motto is "smart is the new cool", the girls can be maddeningly dumb when the plot demands it. In one episode, one of them compromises the location of a safe house by posting pictures to social media. In another, the girls go to ludicrous lengths to deliberately get detention with a potential baddie. These forehead-slapping moments are usually played for laughs, but they really bring down the characters.
Running throughout the show is a tongue-in-cheek commentary about sexism. At one point, an evil mastermind has just been released from prison. During the press conference, the reporters focus their attention on the big guy in the suit, asking what it's like to be free. The woman next to him is like: "Hello? I'm Carson Lazarus. He's my bodyguard." In another episode, one of the girls dubs a boy in a knight costume "Sir Mansplainer" after he butts in to something she was saying. Heh.
My main quibble with the show is that there are no good boy characters. Not only are there no men in the main cast, the recurring and guest characters tend to be more negative portrayals than positive ones. That doesn't stop my son from liking it, but I long for more shows that have more balanced representation, like Miles from Tomorrowland or the latest Star Wars trilogy. Girl power is fun and all, but it shouldn't require running down the boys in the process.
Project MC2 is currently streaming on Netflix.
Overall: My kids argued for a '4', FWIW :)
family,Review
The InBESTigators Review
Star Wars: The Rise of Skywalker Review


text:
/**
 * Contains map store operations.
 */
package com.hazelcast.map.impl.mapstore;

redpajama_set_name: RedPajamaGithub


From Disney by Couture Kingdom's Princess Collection. Celebrating our favourite members of Disney royalty and their unique personalities, these beautifully crafted designs have been created to delight and inspire. Based on the story of Aladdin, these Jasmine stud earrings are everything for the fans of the strong-willed and daring princess.


text:
Why don't cyclists at Cardiff's Naked Bike Ride get arrested for nudity?
Like it or not - under the Sexual Offences Act 2003 - public nudity isn't strictly illegal
Nathan Bevan
Want the best food, film, music, arts and culture news sent straight to your inbox?
Sign up for regular updates of events happening in Wales
The World Naked Bike Ride is all about promoting road safety and highlighting the vulnerability of cyclists.
But if you've ever walked around Cardiff city centre with your kids while the event is going on you might have found the eyefuls of bare flesh on display a little bit difficult to explain to the little ones.
Now, we're all for positive body image but even so, if someone decides to drop their trousers in the middle of Queen Street at chucking out time on a Saturday night or try getting on Valley Lines train during rush hour with nothing to protect their modesty than a season rail ticket, it's likely we'd feel a tap on the shoulder from the Boys in Blue pretty quick.
Back in the saddle - a cyclists brings up the rear on Cathedral Road
So why then is it okay to bare all on a bicycle in broad daylight once a year, whatever the cause behind it may be or however many might be taking part?
Here's everything you need to know...
Turns out being starkers in public isn't illegal
Under the Sexual Offences Act 2003 - being nude in public is permissible, as long as it's not done to intentionally cause harassment, alarm or distress.
It's sentiment echoed by The Crown Prosecution Service also.
Tour de France legend set for Welsh debut
Don't act offensively and you are unlikely to be arrested
Whether you're riding in Cardiff or any of the other routes around the country, such as London , Brighton, Manchester etc, there is almost no risk of being nicked if you are well behaved.
Easy tiger! (Image: Wales News Service)
So the police won't do anything about it?
South Wales Police say they are fully aware of the annual bike protests, the routes and the nudity it involves.
But that doesn't mean that police won't take action if the need arises.
This cleaning firm wants staff in Wales to clean houses naked
For example in 2015, at a naked bike ride in Kent, a cyclist was hauled from the start line and spoken to by officers following reports that he had an erection.
He was ordered to put his jeans on and was not allowed to take part in the event - his personal details were recorded but no further action was taken.
For God's sake, don't turn around
So the absence of any sexual content is a key factor?
Yes - along with those three buzzwords of harassment, alarm or distress - otherwise it could be regarded, according to the CPS, as an offence under section 5 of the Public Order Act 1986, which carries with it the possibility of prosecution, provided it's deemed in the public interest.
So how to I make sure I don't inadvertently see more than I bargained for?
If you're out and about in the capital on the day itself it's probably best to familiarise yourself with the route and the times, that way you can ensure you stay well clear of all the bare bums on saddles.
It starts from Museum Avenue near Sophia Gardens at around 2.30pm before taking in Cardiff Castle , North Road, the Civic Centre, The Hayes and Cardiff Bay, before arriving back at Sophia Gardens at about 5.30pm.
For more information, visit the Cardiff World Naked Bike Ride Facebook page
Follow @WOWalesOnline
Mobile caterer devastated that land she's on could become a Burger King
BridgendMeg's Grill and Chill has been trading on the site for two years, but the first the owner heard about the plan was from a customer
Halfords gives an update on Newport stores as the chain pushes ahead with UK closures
NewportThe British retailer announced last summer it would close 60 stores and garages across the UK
Extra car parking spaces will be created at one of Swansea's busiest retail parks
SwanseaIt will help facilitate more shoppers during busy periods
Taco Bell confirms opening date for new Swansea restaurant is next month
SwanseaNew jobs are coming to the city as the firm sets up shop in an old Oxford Street bank
Work on redeveloping Newport Market is finally set to start in the next week
NewportIt is hoped the project will be completed by Christmas
Hotel boss insists Covid jab will lift gloom for summer holidaymakers
TravelDirector of Spain's Palladium Hotel Group said vaccine and advances in testing technology would allow travel to resume in the coming months


text:
require 'client'
require 'fakeredis'

class TestClient < Client
  attr_reader :sent, :repository, :joined_channels

  def initialize
    @sent = {}
    @channels = []
    @joined_channels = []
  end

  def post(type, channel, text='')
    channel = "##{channel}" unless channel.start_with? '#'
    if type == PRIVMSG
      @sent[channel] << text
    elsif type == JOIN
      @sent[channel] ||= []
      @joined_channels << channel[1..-1]
    elsif type == PART
      @joined_channels.delete channel[1..-1]
    end
  end

  def meta_channel=(channel)
    @sent[channel] ||= []
    @meta_channel = channel
  end
end

Before do
  @client = TestClient.new
  @client.on_rpl_welcome(nil)
end


The relationship between innovation and productivity may also be dependent on the business environment in which firms operate. Business environments are predominantly a country-level characteristic, with some variation across industries and regions within an individual country. Thus, in firm-level analysis they are typically subsumed within "fixed effects" in regressions. In order to see how business environments and innovation may combine to affect growth, the next section makes use of cross-country data.
The growth rates of industries' exports can be affected by a number of country-level characteristics (such as macroeconomic conditions or political stability), as well as a number of industry-level characteristics. For instance, industries which cater for consumer demand in emerging markets may grow faster.
In addition, certain industries may grow faster in countries with specific characteristics. In particular, better economic institutions may enable the exports of innovation-intensive industries to grow more rapidly.
Indeed, poor economic institutions – high incidence of corruption, weak rule of law, burdensome red tape, and so on – can substantially increase the cost of introducing new products and greatly increase the uncertainty of returns to investment in new products and technologies. As a result, risk-adjusted returns to innovation may look less attractive when economic institutions are weak. This will primarily affect industries where the introduction of new products and technologies is essential in order to maintain the competitiveness of exports, so firms tend to introduce new products more frequently – in other words, innovation-intensive industries.
The BEEPS results provide some support for this view. Firms that have introduced a new product in the last three years regard all aspects of their immediate business environment as a greater constraint on their operations than firms that do not innovate. Such differences between innovative and non-innovative firms' perception of their business environment are particularly large when it comes to the skills of the workforce, corruption and customs and trade regulations (as discussed in more detail in Chapter 3).
In order to examine the relationship between the quality of economic institutions and the growth of innovative industries, we can look at growth rates for the exports of various industries in various countries.30 These can be explained by country fixed effects (roughly corresponding to the average growth rates of total exports in individual countries) and industry fixed effects (namely the average growth rates of global exports for individual industries), as well as the initial exports of a given industry in a given country, expressed as a percentage of that country's total goods exports. In addition, regressions include interaction terms between the innovation intensity of a given industry and a country-level characteristic: either the quality of economic institutions or the level of financial development. A positive and significant coefficient for the interaction term between innovation intensity and the quality of economic institutions would imply that innovation-intensive exports grow relatively fast compared with other exports in countries that have superior economic institutions.
The results are presented in Table 2.4. They suggest that the exports of innovation-intensive industries do grow faster relative to other exports in countries with stronger economic institutions and that this effect is statistically significant. These estimates also indicate that the impact the quality of institutions has on the relative performance of innovation-intensive exports is greater in emerging/developing economies than it is in advanced economies (where the quality of economic institutions tends to be higher).
In order to understand the magnitude of this effect, we can look at one industry which is in the top 25 per cent in terms of innovation intensity (for instance, pharmaceuticals) and another which is in the bottom 25 per cent (such as basic metals). A 1-standard-deviation improvement in the quality of economic institutions (say, from the level of Albania to that of Poland) will boost the average growth rate of the exports of the more innovation-intensive industry, pharmaceuticals, by an extra 0.35 percentage point a year relative to the growth rate of basic metals. In the case of emerging markets, the extra growth premium for the more innovation-intensive industry stands at 0.95 percentage point a year. This is a sizeable difference, given that the median rate of growth across all industries and countries in the sample is around 8 per cent.
The specifications reported in columns 3 and 4 suggest a similar relationship with financial development, with the exports of innovation-intensive industries also growing faster relative to other exports in countries with higher credit-to-GDP ratios. This reflects the fact that industries that are more innovation-intensive may be more reliant on the availability of credit in order to fund investment in the development of new products (as discussed in more detail in Chapter 4 of this report).
Source: Authors' calculations using data from UN Comtrade and Feenstra et al. (2005) (exports data), US Bureau of Labor Statistics (deflators, employment), USPTO (US patent grants), and the World Bank's Worldwide Governance Indicators (ratio of private-sector credit to GDP).
Note: The dependent variable is average annual growth in exports for a given industry in a given country between 1990 and 2010. Export values have been deflated using industry-specific deflators calculated for US industries. As the United States is used to estimate the innovation intensity of industries, it is excluded from all regressions. All regressions include country and industry fixed effects. Data on Worldwide Governance Indicators are averages for the period 1996-2010; data on the ratio of private-sector credit to GDP are averages for the period 1990-2010. Robust standard errors are indicated in parentheses. ***, ** and * denote statistical significance at the 1, 5 and 10 per cent levels respectively.


text:
Sit On Satan's Lap At Oklahoma's Capitol Bldg.
Satanists' statue design for Oklahoma Capitol: 'Sit on the lap of Satan'
Members of the Satanic Temple have unveiled their design for a 7-foot-tall statue of the devil they want to locate at the Capitol building in Oklahoma, right next to a monument of the Ten Commandments that has stood since 2012.
And to many, the design may prove shocking.
The Associated Press reported an artist's depiction shows Satan as the goat-headed and horned figure of Baphomet, complete with wings and a long beard. The Satan figure is shown sitting on a throne decorated with pentagrams, in the middle of a few smiling children.
"The monument has been designed to reflect the views of Satanists in Oklahoma City and beyond," said Lucien Greaves, a spokesman for the group, in a statement reported by the AP. "The statue will also have a functional purpose as a chair where people of all ages may sit on the lap of Satan for inspiration and contemplation."
The group is based in New York, but says it's not fair for Oklahoma lawmakers to let a Ten Commandments statue stand at the building, without also allowing monuments that reflect other spiritual beliefs, The Associated Press reported. The Ten Commandments statue was privately funded. The American Civil Liberties Union sued to have it removed shortly after it was place, AP reported.
And the Satanic Temple isn't the only group seeking equal access to the site.
READ MORE OF THIS ARTICLE: CLICK HERE
SOURCE: The Washington Times


Bangkok - a city on the southern coast of Thailand. Bangkok is the capital of Thailand and at the same time the largest city in the country. The population of Bangkok in 2014 was six and a half million people. Bangkok is a large tourist and business center of Asia. Bangkok annually attracts more than 100 million tourists and businessmen.


text:
La démodécie ou gale folliculaire est une maladie de peau touchant le chien et due à l'infestation des follicules pileux par un acarien microscopique de forme allongée (vermiforme), appelé . Couramment nommée « gale démodécique », elle ne doit pour autant pas être confondue avec la gale sarcoptique, qui est une maladie provoquée par un acarien différent.

Le  fait partie de la flore normale de la peau du chien, où on les retrouve en très petit nombre. Ils sont transmis de la mère aux chiots vers l'âge de 2-3 jours.  Les chiens atteints de démodécie ont un nombre accru de ces acariens dans leurs follicules pileux.  Cette maladie n'est pas contagieuse pour l'homme, mais elle peut l'être pour les autres chiens, notamment s'il s'agit de chiots ou si leur système immunitaire est fragilisé.

La démodécie est associée à une prédisposition héréditaire de certains individus, causant une déficience temporaire et réversible de leur système immunitaire. Cette maladie touche surtout les jeunes chiens (entre 3 et 12 mois). Il arrive toutefois que des chiens âgés expriment la maladie soit à la suite d'une immunodéficience, soit secondairement à une autre maladie (dysendocrinie, atteinte tumorale).

Symptômes
Les lésions dermatologiques principales lors de démodécie sont des pertes de poils circonscrites ou étendues. On observe aussi souvent des squames (pellicules). Parfois la démodécie est compliquée par l'apparition d'une surinfection bactérienne de la peau (on parle alors de pyodémodécie) ou par une réaction inflammatoire cutanée importante.

Ses formes
Il existe plusieurs formes de démodécie :
 La démodécie sèche ou démodécie localisée, qui s'observe chez les chiots de trois à douze mois. Celle-ci peut se présenter sous une forme localisée (lésions sur les membres, au niveau des espaces inter-digités notamment, et sur la face, principalement autour des yeux) ou sous une forme disséminée (dépilations diffuses, séborrhée, forte odeur cutanée). En général, on n'observe pas de démangeaisons. Les chiens atteints de ce type de démodécie guérissent, dans 90 % des cas, sans séquelle.

 La démodécie généralisée, démodécie suppurée ou pyodémodécie. Cette forme grave survient lorsque la démodécie sèche se complique d'une infection cutanée bactérienne très importante. On note alors une pyodermite profonde, ayant pour origine principale une infection par des staphylocoques. La peau devient suintante et se couvre de croûtes. On observe aussi des démangeaisons importantes et une hyperkératose. Il arrive que la maladie soit tellement grave qu'elle se répercute sur l'état général de l'animal. Le chien devient alors abattu, amaigri et déshydraté. Parfois, la mort survient.

Diagnostic

Le diagnostic de la démodécie se fait à partir de l'examen microscopique de prélèvements obtenus à la suite de raclages (grattages) cutanés. On met en évidence le parasite, dont l'aspect est caractéristique.

Traitement
Après identification du parasite, le traitement peut être soit oral (molécule spécialement orientée vers le Demodex) ou externe (bains d'acaricide). Dans un cas comme dans l'autre, le traitement est toujours assez long, allant de plusieurs semaines à plusieurs mois. Un contrôle régulier doit être réalisé en effectuant des raclages cutanés. Le traitement peut être suspendu quand on n'observe plus de parasites sur deux raclages réalisés à une semaine d'intervalle.

Les récidives sont peu fréquentes (10 % des cas).

On recommande de faire stériliser les chiennes atteintes de démodécie généralisée, car les changements hormonaux reliés aux chaleurs ou à la gestation peuvent favoriser une rechute.  Le rôle joué par les prédispositions héréditaires donne une raison supplémentaire pour stériliser l'animal infecté.

Voir aussi

 Définition et prise en charge de la démodécie en pratique vétérinaire

Santé du chien

redpajama_set_name: RedPajamaWikipedia


Rotherham Driving Schools | Driving Instructors in Rotherham | Driving Lessons Rotherham.
Driving Schools Finder Rotherham Driving School page, We have listed several Driving Schools and Driving Instructors in Rotherham. If you know of a Driving School or Driving Instructor in Rotherham that we missed Please Submit it at: Listings Page. The listings below will help you find cheap driving lessons, weekend driving lessons, night driving lessons, intensive driving lessons and driving courses in Rotherham. Driving Schools Finder will help you find all Driving Schools in Rotherham with our big maps.


The single from Getaway Dogs ebbs and flows like a shimmering ocean wave crashing against a kaleidoscope skyline. "Excuses/Opinions II" floats into the carefree layers of atmosphere with ethereal harmonies, shimmering guitar, and a wandering bass line. A reissue from their 2016 album Lost In The Ebb, the newly recorded song was redone to convey the energy and soul of the band's live performance to put the listener front and center.
"Excuses/Opinions II" paints with a psychedelic pallet ranging in colors of jazz, hip-hop, and Brazilian finger-picking. The colors stretch the canvas while singer and guitarist Kai Killion sings in an inviting cadence. Since much of the music was inspired by the seafoam home in which the band resides, the bubbling coastal influences can be felt through each note. Accents of synth complement the melody and add a final layer to the finished product. It's easy to imagine driving past a hidden reef to a surf mecca while the music flows in to mix with the sand.
Getaway Dogs is the brainchild of Kai Killion. Prior to this band, Killion made one solo album called Mermaid Legs & Getaway Dogs (2013), where the band name was born. Their debut album, Lost In The Ebb, was released in 2016. They have shared the stage with notable acts such as Tommy Guerrero, Durand Jones & The Indications, and Space Captain, and have been a part of festivals such as Do-It-Ourselves Fest and the Mill Valley Fall Arts Festival. The band currently consists of Killion (guitars/vocals), Spencer Higgins (drums, percussion), Lucas Heinel (percussion, synth) and Chili Corder (bass).


text:
Trigger – Churning the Waters
Wednesday, 19th July 2017 By Matt Coe
Providing a potent mixture of the old with the new, Trigger aim to set their sights on international audiences with their latest release Cryogenesis. It's not very often that you have a band willing to dish out classic hooks and melodies while also tapping into the aggression of thrash and melodic death riffing and tempos- making these elements gel together cohesively. Yet this quintet does – and they'll be the first to tell you that they love Iron Maiden and Megadeth just as much as say Trivium or In Flames through their arrangements and musical execution.
We recently set up a Skype session with one of the guitarists Luke Ashley – an amiable gentleman who feels fortunate to be a part of a burgeoning country wide metal movement. In this interview, we handle the history of the group, his work as a guitar teacher in a reputable guitar academy, as well as how it is playing in a band with his father – beyond a bit of Cryogenesis discussion of course.
Dead Rhetoric: Take us back to the formation of Trigger in 2012 – how did everyone come into the picture, and did you know straight away the type of melodic metal you wanted to develop or was there a natural feeling out process to arrive at where you are musically?
Luke Ashley: It started off, none of us had ever really been involved in the Australian metal scene before. We were all looking for a bassist, who we happened to find over the internet. Our drummer was a local friend from work. Our vocalist came to us through a chance happening. We eventually decided to come to a sound that was going to be more like Iron Maiden. We got heavier as time went on, we started listening to heavier music, and we took on some more modern influences. That's fairly apparent through the sound of our Mechania EP and the new album Cryogenesis.
Dead Rhetoric: The Mechania EP came out in early 2014 – how do you feel about the final product in terms of songwriting, performances, production, and overall development? Where do you see the strengths and weaknesses now having a few years to look back on things?
Ashley: There was a different curve in terms of the songwriting. The songwriting was more guitar based and guitar driven, where it was quite apparent that the songs were being written by the guitarists. Those guitars really drove the EP. With Cryogenesis, we took the time to really learn how to write for the vocalist, and how the narrative can take over versus writing a collection of riffs. The weakness for the EP would be, there wasn't as much of a narrative element for those songs.
Dead Rhetoric: How did the deal with Hellfire Records happen? Do you feel it's great stepping stone, even as a local label, for Trigger to move up the ranks?
Ashley: Hellfire Records happened I believe, Bo (Remy) from Hellfire Records contacted our guitarist Sean (Solley). It was interesting discussing the deal, we were fairly perceptive and we liked what was offered to us. We talked it up, said yes, and we call this a fetal (baby) label- it's not a full deal, (but) with a distribution deal for Cryogenesis. We will use this for the first 500 copies and see where things go from there. We may stay with Hellfire from there, or see if things can go up the ranks. We are seeing how far we can push ourselves with this release.
Dead Rhetoric: Your latest album Cryogenesis showcases a great fusion of melodic metal that contains everything from groovier hooks to twin guitar harmonies, also reaching thrash/melodic death segments. How do you feel you've grown in the three years between releases, and what surprises/developments took place to make this effort stronger?
Ashley: As the primary songwriters for the early material are Sean and myself, he is very European based with his influences, and I am a bit more American driven in my writing. It's a real meeting of both minds and both styles. I write from a place where I think the hook is the absolute, most important thing in a piece of music. Every song we write can vary in style, but there are always hooks and strong counterpoint parts off of that. That's our staple above anything else, over any particular style, our attention to hooks.
Dead Rhetoric: What do you believe producer Chris Themelco (Orpheus Omega) brings to the table to help Trigger achieve more of what you wanted in the studio? Are there any specific insights or tips that you applied?
Ashley: Absolutely, Chris is fantastic. We went in and tracked everything with Chris- I was very interested in his insight in finalizing the writing process. He was a huge help in terms of the harmonies, the counter melodies through choruses, to really flesh them out and make them sound suitably broad but complex. So that was mostly for harmonies through the bar chords on guitar.
Dead Rhetoric: Where does Trigger come from on a lyrical content standpoint? Do you prefer keeping the topics on more of a social/political level to match the aggression and energy of the music, or do other influences come into the picture?
Ashley: We wrote Cryogenesis as a bit of a concept album. It wasn't full-fledged, but we have an overarching world that we are singing about. We found a narrative about a location in the world or some mythological event, and give it our spin to fit into this world. There are a few songs that deal with more of the human psyche, such "Dead Sun" and "Dysphoria", and other ones that have more of a directional narrative such as "Tethered to the Tide" or "Veins of Ambrosia", those are more tied to specific areas of the world. More of our emotional influences come through there.
Dead Rhetoric: And how did the cover art develop for this record?
Ashley: We wanted to go with something that had a bit more power. I found Janan (Isk) as a local artist, and without saying too much about his work, there was one thing that stood out to me. I just liked the sci-fi elements that we had, I thought about having strong brains – I contacted him right away, and he was happy to go through with this.
Dead Rhetoric: It appears as if the Melbourne metal scene – or Australia as a whole – seems like a hotbed not just in one specific sub-genre, but provides a wealth of talent in numerous styles be it melodic or extreme. How do you feel about the local scene, are the fans, promoters, and venues generally as supportive of the local bills as the international artists and tours that come through?
Ashley: Yes, absolutely. Melbourne is an absolute breeding ground for talent. Especially when it comes to bands looking to break through into international waters. It becomes quite competitive to each other almost, in terms of how you can craft a song and how complex of a piece you put together. There can be a back and forth between artists. Each city in Australia seems to have its own strength as far as subgenres- Melbourne is a bit more thrash-oriented, Sydney is a bit more power metal oriented, over in Brisbane that is a little bit more metalcore, it's all different depending where you go at least in terms of the strength based on the genre. Melbourne is quite eclectic and a scene that I am very proud to be a part of.
Dead Rhetoric: You play in this band with your father as the two guitarists. What does this mean for you to have such a strong support system, and where do you see the benefits considering your old to new generation outlook as players and performers within a metal band?
Ashley: It's an absolute pleasure to play alongside Sean week in and week out. It's done a 180 on our relationship. We are more mates than anything else. It's an honor to share that. In terms of musicality, he's far more feel driven, while I'm very much theory-based. We look at music in a completely different way, each of us. We cover each other's weaknesses there. We understand how each other plays, we really gel well together live even though we come from completely different backgrounds.
Dead Rhetoric: Do you end up picking out spots for who handles the lead work based on those individual strengths?
Ashley: Yes. I prefer taking more structured leads, and he'll take any leads that require a bit more aggression.
Dead Rhetoric: Being a guitar teacher as a day job, what type of students do you work with, and where do you see the greatest struggles or hurdles that players need to overcome – are there specific exercises or ideas that you implement to improve technique and skill sets?
Ashley: I work with people from the age of six to sixty-plus. The greatest hurdle is that mental hurdle, of making sure you are practicing every day. And not just practicing, practicing the right way. Have somebody guide you and making sure that the time you do put into practice is time well spent, is the most important thing. Making sure that your technique is right, and you are not practicing the wrong things so that you have to go back and fix them are absolutely paramount.
Dead Rhetoric: Are there people that come to you excited to know that you play in a metal band?
Ashley: I believe so. I think it sort of fulfills a bit of a fantasy, as such. It opens up an avenue where you can go from learning an instrument to having fun. The institution I teach at, Melbourne Guitar Academy, we are driven towards that heavy style and we are up to that style of training people to be guitar ninjas. Making sure that they can get on the stage if they want to.
Dead Rhetoric: Do you find there are people that are afraid of the changes in technology and keeping up with things when it comes to equipment?
Ashley: I'd say no more than myself. The world has changed very, very much in the last 15 years- the whole industry has had to adapt, and I think they are still struggling with it. Where does the whole movement of piracy, online streaming, and downloads go- it's the most prevalent way to send your music across, and independent artists all over the world. It's better if you are coming into music just now because you aren't into an old way of thinking- you can come into this with fresh ideas and adapt on the fly.
Dead Rhetoric: Are there any specific bands that you look up to as a template for how you would like to see the career arc of Trigger go on – either in terms of the musical output, or professionalism with their live performances and business/branding presentation?
Ashley: Yeah. I'd say within the Australian base, someone like Parkway Drive. Being how they have managed to capture international audiences and explode. I believe they were a bit of a one-off case, but it does show that it can be done in Australia in the modern day. I really like the way that they've worked themselves and carried themselves. In terms of musicality, going off more of the influences, I would put down things like Trivium, Iron Maiden, and In Flames.
Dead Rhetoric: What are your thoughts on the power of social media these days – do you consider its importance across numerous platforms in keeping your fans engaged and building more of a profile for the band?
Ashley: You simply can't succeed without a strong social media presence. You have to be on it, it's a great thing to have as a band. The only person that will push your band is yourself, at the end of the day. With everybody on social media, it's going to come down to who's willing to put in the most effort, in the most appropriate way. Essentially it puts everybody on the same level playing field, it's a matter then of who is going to put in the most effort. It's great to access fans from all over the world, and very good for the fans to access their favorite bands from all over the world. If you put the effort in, you can reap the rewards.
Dead Rhetoric: Tell us three albums that have had the greatest impact on your personal affinity and views of heavy metal, and what have been some of your favorite live shows memories purely from a spectator outlook?
Ashley: Three albums, I would say Follow the Reaper by Children of Bodom, Shogun by Trivium, and Temple of Shadows by Angra. A little bit of Scandinavian death, a little bit of power metal, and the modern touch. You have hooks all over the albums, very mature writing, and very melodic as well. In terms of live shows, I'd say my crowning moment would have been seeing Ronnie James Dio in Heaven and Hell when I was 15. That was quite an impressive moment, especially at that age.
Dead Rhetoric: What obsessions or passions do you explore on the evenings, weekends, or in free time when you are able to do so?
Ashley: These days I mostly play guitar, above anything else. Just exploring where I can take the guitar, and learning different styles of jazz and the progressions. Seeing how I can take things in and apply them to our next release. I'm just passionate about music.
Dead Rhetoric: Will it be a juggling act for drummer Tim Joyce to balance his work between Harlott and yourselves, and how did bassist Matt Ambrose gain the chance to work with Pegazus? Do you feel the opportunities open horizons for Trigger in the long term?
Ashley: Yes, it certainly is a juggling act between Harlott and Trigger, but we have toured with Harlott. We have a good relationship with them. In regards to Pegazus, we are able to share a lot of double bills with the band, as long as Matt and Tim are up for the challenge, it becomes a much more exciting show for everyone involved.
Dead Rhetoric: How do you see the next six months to a year playing out for Trigger in terms of promotion and performances? Has songwriting already begun on the follow up, and if so how do you feel this material compares to Cryogenesis?
Ashley: Yes, I'll be going into pre-production tonight actually for album two. We've written a few songs already, and we are just feeling out the direction of the next one. If we want to take on a heavier ideal, or stick to a more classic aspect. We are just churning the waters at the moment. I can't say too much, I don't want to spoil everything. In terms of tours, we will be doing an Australian tour, and we will be looking at potentially international things down the line. We'll be revealing a video at the time of the release – and a more conceptual video as well.
Cryogenesis by Trigger
Trigger on Facebook
Trigger – Cryogenesis (Hellfire Records)


text:
A membrane transport protein (or simply transporter) is a membrane protein[1] involved in the movement of ions, small molecules, and macromolecules, such as another protein, across a biological membrane. Transport proteins are integral transmembrane proteins; that is they exist permanently within and span the membrane across which they transport substances. The proteins may assist in the movement of substances by facilitated diffusion or active transport. The two main types of proteins involved in such transport are broadly categorized as either channels or carriers. The solute carriers and atypical SLCs[2] are secondary active or facilitative transporters in humans.[3][4] Collectively membrane transporters and channels are known as the transportome.[5] Transportomes govern cellular influx and efflux of not only ions and nutrients but drugs as well.
Difference between channels and carriers
A carrier is not open simultaneously to both the extracellular and intracellular environments. Either its inner gate is open, or outer gate is open. In contrast, a channel can be open to both environments at the same time, allowing the molecules to diffuse without interruption. Carriers have binding sites, but pores and channels do not.[6][7][8] When a channel is opened, millions of ions can pass through the membrane per second, but only 100 to 1000 molecules typically pass through a carrier molecule in the same time.[9] Each carrier protein is designed to recognize only one substance or one group of very similar substances. Research has correlated defects in specific carrier proteins with specific diseases.[10]
Main article: Active transport
The sodium–potassium pump is found in many cell (plasma) membranes and is an example of primary active transport. Powered by ATP, the pump moves sodium and potassium ions in opposite directions, each against its concentration gradient. In a single cycle of the pump, three sodium ions are extruded from and two potassium ions are imported into the cell.
Active transport is the movement of a substance across a membrane against its concentration gradient. This is usually to accumulate high concentrations of molecules that a cell needs, such as glucose or amino acids. If the process uses chemical energy, such as adenosine triphosphate (ATP), it is called primary active transport. Secondary active transport involves the use of an electrochemical gradient, and does not use energy produced in the cell.[11] Unlike channel proteins which only transport substances through membranes passively, carrier proteins can transport ions and molecules either passively through facilitated diffusion, or via secondary active transport.[12] A carrier protein is required to move particles from areas of low concentration to areas of high concentration. These carrier proteins have receptors that bind to a specific molecule (substrate) needing transport. The molecule or ion to be transported (the substrate) must first bind at a binding site at the carrier molecule, with a certain binding affinity. Following binding, and while the binding site is facing the same way, the carrier will capture or occlude (take in and retain) the substrate within its molecular structure and cause an internal translocation so that the opening in the protein now faces the other side of the plasma membrane.[13] The carrier protein substrate is released at that site, according to its binding affinity there.
Facilitated diffusion
Main article: Facilitated diffusion
Facilitated diffusion in the cell membrane, showing ion channels (left) and carrier proteins (three on the right).
Facilitated diffusion is the passage of molecules or ions across a biological membrane through specific transport proteins and requires no energy input. Facilitated diffusion is used especially in the case of large polar molecules and charged ions; once such ions are dissolved in water they cannot diffuse freely across cell membranes due to the hydrophobic nature of the fatty acid tails of the phospholipids that make up the bilayers. The type of carrier proteins used in facilitated diffusion is slightly different from those used in active transport. They are still transmembrane carrier proteins, but these are gated transmembrane channels, meaning they do not internally translocate, nor require ATP to function. The substrate is taken in one side of the gated carrier, and without using ATP the substrate is released into the cell.
Reverse diffusion
Main article: Reverse transport
Reverse transport, or transporter reversal, is a phenomenon in which the substrates of a membrane transport protein are moved in the opposite direction to that of their typical movement by the transporter.[14][15][16][17][18] Transporter reversal typically occurs when a membrane transport protein is phosphorylated by a particular protein kinase, which is an enzyme that adds a phosphate group to proteins.[14][15]
(Grouped by Transporter Classification database categories)
1: Channels/pores
α-helical protein channels such as voltage-gated ion channel (VIC), ligand-gated ion channels(LGICs)
β-barrel porins such as aquaporin
channel-forming toxins, including colicins, diphtheria toxin, and others
Nonribosomally synthesized channels such as gramicidin
Holins; which function in export of enzymes that digest bacterial cell walls in an early step of cell lysis.
Facilitated diffusion occurs in and out of the cell membrane via channels/pores and carriers/porters.
Channels are either in open state or closed state. When a channel is opened with a slight conformational switch, it is open to both environment simultaneously (extracellular and intracellular)
This picture represents symport. The yellow triangle shows the concentration gradient for the yellow circles while the green triangle shows the concentration gradient for the green circles and the purple rods are the transport protein bundle. The green circles are moving against their concentration gradient through a transport protein which requires energy while the yellow circles move down their concentration gradient which releases energy. The yellow circles produce more energy through chemiosmosis than what is required to move the green circles so the movement is coupled and some energy is cancelled out. One example is the lactose permease which allows protons to go down its concentration gradient into the cell while also pumping lactose into the cell.
Pores:
Pores are continuously open to these both environment, because they do not undergo conformational changes. They are always open and active.
2: Electrochemical potential-driven transporters
Also named carrier proteins or secondary carriers.
2.A: Porters (uniporters, symporters, antiporters), SLCs.[4]
The picture represents uniport. The yellow triangle shows the concentration gradient for the yellow circles and the purple rods are the transport protein bundle. Since they move down their concentration gradient through a transport protein, they can release energy as a result of chemiosmosis. One example is GLUT1 which moves glucose down its concentration gradient into the cell.
Excitatory amino acid transporters (EAATs)
Glucose transporter
Monoamine transporters, including:
Dopamine transporter (DAT)
Norepinephrine transporter (NET)
Serotonin transporter (SERT)
Vesicular monoamine transporters (VMAT)
Adenine nucleotide translocator (ANT)
2.B: Nonribosomally synthesized porters, such as:
The Nigericin family
The Ionomycin family
2.C: Ion-gradient-driven energizers
3: Membrane transport protein
3.A: P-P-bond-hydrolysis-driven transporters :
ATP-binding cassette transporter (ABC transporter), such as MDR, CFTR
V-type ATPase ; ( "V" related to vacuolar ).
P-type ATPase ; ( "P" related to phosphorylation), such as :
Na+/K+-ATPase
Plasma membrane Ca2+ ATPase
Proton pump
This picture represents antiport. The yellow triangle shows the concentration gradient for the yellow circles while the blue triangle shows the concentration gradient for the blue circles and the purple rods are the transport protein bundle. The blue circles are moving against their concentration gradient through a transport protein which requires energy while the yellow circles move down their concentration gradient which releases energy. The yellow circles produce more energy through chemiosmosis than what is required to move the blue circles so the movement is coupled and some energy is cancelled out. One example is the sodium-proton exchanger which allows protons to go down their concentration gradient into the cell while pumping sodium out of the cell.
F-type ATPase; ("F" related to factor), including: mitochondrial ATP synthase, chloroplast ATP synthase1
3.B: Decarboxylation-driven transporters
3.C: Methyltransfer-driven transporters
3.D: Oxidoreduction-driven transporters
3.E: Light absorption-driven transporters, such as rhodopsin
4: Group translocators
The group translocators provide a special mechanism for the phosphorylation of sugars as they are transported into bacteria (PEP group translocation)
5: Electron carriers
The transmembrane electron transfer carriers in the membrane include two-electron carriers, such as the disulfide bond oxidoreductases (DsbB and DsbD in E. coli) as well as one-electron carriers such as NADPH oxidase. Often these redox proteins are not considered transport proteins.
Every carrier protein, especially within the same cell membrane, is specific to one type or family of molecules. For example, GLUT1 is a named carrier protein found in almost all animal cell membranes that transports glucose across the bilayer. Other specific carrier proteins also help the body function in important ways. Cytochromes operate in the electron transport chain as carrier proteins for electrons.[11]
A number of inherited diseases involve defects in carrier proteins in a particular substance or group of cells. Cysteinuria (cysteine in the urine and the bladder) is such a disease involving defective cysteine carrier proteins in the kidney cell membranes. This transport system normally removes cysteine from the fluid destined to become urine and returns this essential amino acid to the blood. When this carrier malfunctions, large quantities of cysteine remain in the urine, where it is relatively insoluble and tends to precipitate. This is one cause of urinary stones.[19] Some vitamin carrier proteins have been shown to be overexpressed in patients with malignant disease. For example, levels of riboflavin carrier protein (RCP) have been shown to be significantly elevated in people with breast cancer.[20]
Cotransport
C14orf102, a 3810bp protein-encoding gene
Permease
P-loop
Solute carrier family (classification)
TC number (classification)
Translocase
Vesicular transport protein
^ Membrane+transport+proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
^ Perland, Emelie; Bagchi, Sonchita; Klaesson, Axel; Fredriksson, Robert (2017-09-01). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. ISSN 2046-2441. PMC 5627054. PMID 28878041.
^ Hediger, Matthias A.; Romero, Michael F.; Peng, Ji-Bin; Rolfs, Andreas; Takanaga, Hitomi; Bruford, Elspeth A. (February 2004). "The ABCs of solute carriers: physiological, pathological and therapeutic implications of human membrane transport proteinsIntroduction". Pflügers Archiv: European Journal of Physiology. 447 (5): 465–468. doi:10.1007/s00424-003-1192-y. ISSN 0031-6768. PMID 14624363. S2CID 1866661.
^ a b Perland, Emelie; Fredriksson, Robert (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. ISSN 1873-3735. PMID 27939446.
^ Huang, Y; Anderle, P; Bussey, KJ; Barbacioru, C; Shankavaram, U; Dai, Z; Reinhold, WC; Papp, A; Weinstein, JN; Sadée, W (15 June 2004). "Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance". Cancer Research. 64 (12): 4294–301. doi:10.1158/0008-5472.CAN-03-3884. PMID 15205344. S2CID 2765236.
^ Sadava, David, et al. Life, the Science of Biology, 9th Edition. Macmillan Publishers, 2009. ISBN 1-4292-1962-9. p. 119.
^ Cooper, Geoffrey (2009). The Cell: A Molecular Approach. Washington, DC: ASM Press. p. 62. ISBN 9780878933006.
^ Thompson, Liz A. Passing the North Carolina End of Course Test for Biology. American Book Company, Inc. 2007. ISBN 1-59807-139-4. p. 97.
^ Assmann, Sarah (2015). "Solute Transport". In Taiz, Lincoln; Zeiger, Edward (eds.). Plant Physiology and Development. Sinauer. p. 151.
^ a b Ashley, Ruth. Hann, Gary. Han, Seong S. Cell Biology. New Age International Publishers. ISBN 8122413978. p. 113.
^ Taiz, Lincoln. Zeigler, Eduardo. Plant Physiology and Development. Sinauer Associates, 2015. ISBN 978-1-60535-255-8. pp. 151.
^ Kent, Michael. Advanced Biology. Oxford University Press US, 2000. ISBN 0-19-914195-9. pp. 157–158.
^ a b Bermingham DP, Blakely RD (October 2016). "Kinase-dependent Regulation of Monoamine Neurotransmitter Transporters". Pharmacol. Rev. 68 (4): 888–953. doi:10.1124/pr.115.012260. PMC 5050440. PMID 27591044.
^ a b Miller GM (January 2011). "The emerging role of trace amine-associated receptor 1 in the functional regulation of monoamine transporters and dopaminergic activity". Journal of Neurochemistry. 116 (2): 164–176. doi:10.1111/j.1471-4159.2010.07109.x. PMC 3005101. PMID 21073468.
^ Scholze P, Nørregaard L, Singer EA, Freissmuth M, Gether U, Sitte HH (2002). "The role of zinc ions in reverse transport mediated by monoamine transporters". The Journal of Biological Chemistry. 277 (24): 21505–13. doi:10.1074/jbc.M112265200. PMID 11940571.
^ Robertson SD, Matthies HJ, Galli A (2009). "A closer look at amphetamine-induced reverse transport and trafficking of the dopamine and norepinephrine transporters". Molecular Neurobiology. 39 (2): 73–80. doi:10.1007/s12035-009-8053-4. PMC 2729543. PMID 19199083.
^ Kasatkina LA, Borisova TA (November 2013). "Glutamate release from platelets: exocytosis versus glutamate transporter reversal". The International Journal of Biochemistry & Cell Biology. 45 (11): 2585–2595. doi:10.1016/j.biocel.2013.08.004. PMID 23994539.
^ Sherwood, Lauralee. 7th Edition. Human Physiology. From Cells to Systems. Cengage Learning, 2008. p. 67
^ Rao, PN, Levine, E et al. Elevation of Serum Riboflavin Carrier Protein in Breast Cancer. Cancer Epidemiol Biomarkers Prev. Volume 8 No 11. pp. 985–990
Anderle, P., Barbacioru,C., Bussey, K., Dai, Z., Huang, Y., Papp, A., Reinhold, W., Sadee, W., Shankavaram, U., & Weinstein, J. (2004). Membrane Transporters and Channels: Role of the Transportome in Cancer Chemosensitivity and Chemoresistance. Cancer Research, 54, 4294-4301.
Wikimedia Commons has media related to Membrane transport proteins.
"Transport protein" at Dorland's Medical Dictionary
Proteins: carrier proteins
Fatty acid
FABP1
peptide hormone: Follistatin
Growth hormone binding protein
Insulin-like growth factor binding protein
IGFBP1
Neurophysins
Neurophysin I
steroid hormone: Sex hormone binding globulin/Androgen binding protein
Transcortin
Thyroxine-binding globulin
Transthyretin
Metal/element
Calcium-binding protein
Calmodulin-binding proteins
Iron-binding proteins
Transferrin receptor
Retinol binding protein
Transcobalamin
Plant Light-Harvesting Complex
Orange Carotenoid Protein
Phycobiliprotein
Photosynthetic Reaction Centers
Phytochrome
Rhodopsin
Adaptor protein
Cholesterylester transfer protein
F-box protein
GTP-binding protein
Latent TGF-beta binding protein
Major urinary proteins
Odorant binding protein
Membrane transport protein: ion channels (TC 1A)
Ca2+: Calcium channel
Ligand-gated
Inositol trisphosphate receptor
Ryanodine receptor
Voltage-gated
L-type/Cavα
N-type/Cavα2.2
P-type/Cavα
Q-type/Cavα2.1
R-type/Cavα2.3
T-type/Cavα
α2δ-subunits
β-subunits
γ-subunits
Cation channels of sperm
Two-pore channel
Na+: Sodium channel
Constitutively active
Epithelial sodium channel
Proton-gated
Amiloride-sensitive cation channel
Navα
Navβ
K+: Potassium channel
Calcium-activated
SK channel
IK channel
Inward-rectifier
KATP
GIRK/Kir
Tandem pore domain
Kvα1-6
Kvα7-12
11.1/hERG
Kvβ
KCNIP
minK/ISK
minK/ISK-like
MiRP
Shaker (gene)
Cl−: Chloride channel
Calcium-activated chloride channels
Anoctamin
ANO1
Bestrophin
Chloride Channel Accessory
CLCN
CLNS
H+: Proton channel
HVCN1
M+: CNG cation channel
M+: TRP cation channel
TRPA (1)
TRPC
4AP
TRPM
TRPML
TRPN
TRPV
H2O (+ solutes): Porin
Voltage-dependent anion channel
General bacterial porin family
Cytoplasm: Gap junction
GJA1
GJA10
GJB1
GJC1
GJD2
Innexin
By gating mechanism
Ion channel class
Light-gated
Stretch-activated
see also disorders
Membrane proteins, carrier proteins: membrane transport proteins solute carrier (TC 2A)
high affinity glutamate and neutral amino-acid transporter
SLC1A1
facilitative GLUT transporter
heavy subunits of heterodimeric amino-acid transporters
bicarbonate transporter
sodium glucose cotransporter
sodium- and chloride- dependent sodium:neurotransmitter symporters
SLC6A10
cationic amino-acid transporter/glycoprotein-associated
glycoprotein-associated/light or catalytic subunits of heterodimeric amino-acid transporters
Na+/H+ exchanger
(10):
sodium bile salt cotransport
SLC11–20
proton coupled metal ion transporter
SLC11A211A3
electroneutral cation-Cl cotransporter
human Na+-sulfate/carboxylate cotransporter
urea transporter
proton oligopeptide cotransporter
SLC16A10
Vesicular glutamate transporter 1
vesicular monoamine transporter
folate/thiamine transporter
type III Na+-phosphate cotransporter
Organic anion-transporting polypeptide
SLCO1A2
SLCO1B1
SLCO1C1
SLCO5A1(SLCO6A1)
organic cation/anion/zwitterion transporter
Na+-dependent ascorbic acid transporter
Na+/(Ca2+-K+) exchanger
mitochondrial carrier
multifunctional anion exchanger
fatty acid transport proteins
Na+-coupled nucleoside transport (SLC28A1
facilitative nucleoside transporter
zinc efflux
copper transporter
Acetyl-CoA transporter
type II Na+-phosphate cotransporter
nucleoside-sugar transporter
SLC35B1
SLC35C1
SLC35D1
SLC35E1
proton-coupled amino-acid transporter
sugar-phosphate/phosphate exchanger
System A & N, sodium-coupled neutral amino-acid transporter
metal ion transporter
basolateral iron transporter
Magnesium transporter E
Ammonia transporter
RhAG
RhBG
RhCG
Na+-independent, system-L like amino-acid transporter
Choline-like transporter
Putative sugar transporter
Folate transporter
multidrug and toxin extrusion
Heme transporter
SLCO1–4
O1A2
O1B1
Ion pumps
Symporter, Cotransporter
Na+/K+,Cl−
Na+/Pi3
Na+/Cl−
Na+/glucose
Na+/I−
Cl−/K+
Antiporter (exchanger)
Na+/H+
Na+/Ca2+
Na+/(Ca2+-K+) - Cl−/HCO−
3 (Band 3)
Cl−-formate
Cl−-oxalate
see also solute carrier disorders
Membrane transport protein: neurotransmitter transporters (TC 2.A.1.2)
Vesicular
Vesicular monoamine
VMAT1
Vesicular acetylcholine
Vesicular glutamate
Vesicular GABA
Monoamine
PMAT
Excitatory amino-acid transporter
GABA transporter
Membrane proteins, carrier proteins: membrane transport proteins ABC-transporter (TC 3A1)
B2-3 (B2
B3)
C8-9 (C8, C9)
Sterolin (G5, G8)
see also ABC transporter disorders
Membrane transport protein: ion pumps, ATPases / ATP synthase (TC 3A2-3A3)
F-, V-, and A-type ATPase (3.A.2)
H+ (F-type)
H+ transporting, mitochondrial: ATP5A1
ATP5C1
ATP5D
ATP5E
ATP5F1
ATP5G1
ATP5H
ATP5I
ATP5J
ATP5J2
ATP5L
ATP5L2
ATP5O
ATP5S
H+ (V-type)
H+ transporting, lysosomal: ATP6AP1
ATP6AP2
ATP6V1A
ATP6V1B1
ATP6V1C1
ATP6V1D
ATP6V1E1
ATP6V1F
ATP6V1G1
ATP6V1H
ATP6V0A1
ATP6V0B
ATP6V0C
ATP6V0D1
ATP6V0E
TCIRG1
A-ATPase
found in Archea
P-type ATPase (3.A.3)
3.A.3.1.1: Na+/K+ transporting: ATP1A1
ATP1A2
ATP1B1
3.A.3.1.2: H+/K+
H+/K+ exchanging: ATP4A
3.A.3.1.4: H+/K+ transporting, nongastric: ATP12A
3.A.3.2: Ca2+ (SERCA, PMCA, SPCA) / Ca2+ transporting: ATP2A1
3.A.3.5: Cu2+ transporting: ATP7A
3.A.3.8.8: flippase: ATP8A2
Other/ungrouped:
Na+/K+ – H+
Mg2+ transporting: ATP3
Class I, type 8: ATP8A1
Class II, type 9: ATP9A
Class V, type 10: ATP10A
ATP10B
ATP10D
Class VI, type 11: ATP11A
ATP11C
type 13: ATP13A1
ATP13A2
see also ATPase disorders
Transport proteins
Transmembrane transporters


This work won the account. The RFP said, "Looking for an agency that's willing to take risks". We took them at their word. The campaign was polarizing to say the least, but hugely popular among the target audience of males 18-34.