I'm trying to discover why three out of three of my selected hard-disk recorders refuse to work on my Debian Etch (Demudi) system. Once again I ask myself the relevant questions: Is it me ? Is my computer trying to tell me something ? Is it something I said ? Whatever the reason(s), my reviews of those three programs must remain in limbo until I figure out what's wrong. The applications are all known to run perfectly well on other machines, so I'm sure there's an external problem. When testing new applications one must be prepared with the newest dependencies. CVS sources are often required. Sometimes one must mutter obscure invocations. Alas, I was not sufficiently prepared. Time for a radical shift.
In this entry I'm going to introduce two audio-optimized Linux distributions, Apodio and Dynebolic. Both systems can be run in "live" mode, i.e. you put the distribution disc in your CD drive, you reboot, and voila, you're booted into the system. Basically the live mode runs itself from a RAM disk and the distribution CD. The process is transparent, except for the occasional disc reads. The systems can be installed to a hard-drive, but to keep things simple for myself I've tested them only in live mode.
The designers of Apodio and Dynebolic share an agenda, a plan to put high-quality tools for multimedia creation into the hands of artists all over the world, and they want to make these tools freely available. As a side-effect of this definite agenda these systems have relatively low hardware requirements. Believe me, the software side is high-grade, but the designers have considered that not everyone has access to high-powered hardware.
Apodio 4.3.9 is based on the Mandriva 2006.1 distribution, with a 2.6.12 kernel, ALSA 1.0.9b, and version 0.100.1 of the JACK audio server. I was unable to determine whether the kernel had been optimized for low-latency audio and high-definition MIDI timing, but Apodio's overall performance was impressive.
My machine has an 800 MHz Duron CPU, plenty of memory, and no problems meeting the remaining requirements.
When the Apodio disc takes benevolent control of your computer it presents you with a list of boot options. These options are primarily for language and keyboard layout selection, but the list also includes media check and safeboot options. A nice touch. Further into the boot process you can also select your preferred video resolution.
Apodio recognized all my hardware, including my SBLive and M-Audio sound devices (and in that order). Drivers were auto-installed, and when the Apodio desktop appeared the system was ready for immediate use. Well, almost immediate: First I had to configure JACK, but that was easily accomplished via QJackCtl. I wanted to push the JACK system a bit, so I configured it for sub-12 milliseconds latency. My installed Demudi system won't run safely in that configuration, but Apodio seemed to have no troubles in performance. Some xruns were reported when opening or closing some applications, but none occurred while running them. Impressive.
The only hardware problem I encountered was a show-stopper for networking. I simply could not connect to my cable connection. The right driver is installed, the system correctly identifies the hardware, but drakconnect just doesn't make the connection. I should mention that I have yet to research the problem, hopefully a fix is already available.
The selected audio/MIDI applications include most of the high profile Linux sound and music projects. Ardour is here, along with ecasound, Rosegarden, and MusE. JAMin, Hydrogen, ZynAddSubFX, Jack Rack, BEAST, they're all here. Pd is here, but I wondered why Csound5 is not. Common Music is missing, along with the other members of the CCRMA family of sound and music software. These are all powerful environments with relatively low minimum requirements, perhaps they might be included in a future release ?
After configuring QJackCtl I started the Hydrogen rhythm programmer. I loaded one of the demo songs, clicked on the Play transport button, and behold, there was sound. So I fired up the Jack Rack, loaded a bunch of LADSPA effects, made my connections in QJackCtl, and jammed with my guitar along with Hydrogen's drums. Later I played with the ultra-suave ecamegapedal. No xruns in performance, not one.
I wanted to record my random improvisations into Ardour, but it failed to open, leaving an error message about an illegal instruction. Uh-oh, I'll bet that my Duron is missing support for a Pentium instruction that's been built into the Ardour binary. Oh well, leave it and move on. Let's try Rosegarden.
Rosegarden worked fine, but its interface seemed to have a cultural identity crisis. The mixture of languages throughout the program was comprehensible if you could read enough French and English. I did all right with it, but there does seem to be a problem in the internationalization for Rosegarden. Otherwise the program ran with no problems. I loaded various files into it, standard MIDI files and Rosegarden projects, and I recorded some audio test tracks. No problems at all. Rosegarden is a solid sender, it definitely took the sting out of losing Ardour.
The Audacity and ReZound soundfile editors are included. I also checked out the packaged version of mhWaveedit. I haven't looked at this editor for a long while, but its users have continually reported happiness, particularly with its stable JACK support. As I discovered, mhWaveedit is indeed a very cool program, but you'll have to wait until I write another Linux soundfile editors round-up to learn more about it. Just be sure to check it out yourself when you try Apodio.
I encountered only one other notable problem. The main screen pop-up menu includes an option to switch from the default WindowMaker to the Blackbox window manager. WindowMaker is very nice, but I'm experienced with Blackbox. Alas, clicking on the menu item did nothing. Again, it's not a big deal, WindowMaker is cool (see the Figures), but I would like to use Apodio with Blackbox.
Apodio's selection of video applications includes Cinelerra, Kino, and surprisingly Jahshaka. The system also provides a variety of programs and utilities for streaming and sharing media. Alas, time and space forbid delving into this cornucopia. Fortunately you can delve into Apodio for yourself any time. Just download the latest ISO image, burn to disc, reboot, enjoy.
Denis Rojo, aka jaromil, has designed Dynebolic to meet "... the needs of media activists, artists and creatives as a practical tool for multimedia production". With this goal in mind Dynebolic has been designed to be functional and powerful even on lower-powered hardware. According to its minimum requirements Dynebolic will run on any machine with at least a Pentium processor and 64MB RAM. Since Dynebolic runs in either live or installed modes you don't even need a hard disk. Oh, and if you have an Xbox you can even run Dynebolic on that hardware.
Dynebolic has an interesting technical history, you can read about it in this entry on Dynebolic in Wikipedia. I won't repeat that material here, you should read it yourself, but I will note that it states that Dynebolic's 2.6.17 kernel has been modified for low-latency multimedia performance.
Dynebolic's boot options include ACPI control, a special kernel image for debugging the system, and of course the expected choices for screen resolution. The system recognized all my hardware without complaint, even installing the drivers for my soundcards in my preferred order (Delta 66 as Card 0, SBLive as Card 1). Alas, I had no luck with my networking hardware. As with Apodio, the system recognizes the Ethernet card and installs the correct driver. The networking configuration dialog reports no difficulties, but I just can't make a connection. Is there something I'm missing with regards to using a Tulip Ethernet driver, a cable modem, a Linksys router, and Linux ? Even my Demudi system can't make the connection automatically, I invariably have to call pump -i eth0 to get hooked up to the Internet. Unfortunately the pump binary isn't included with Dynebolic (or Apodio) and I haven't yet discovered what other utility will do the same job. No fear, I don't need the networking right away, so let's move on to check out Dynebolic's selected soundapps.
WindowMaker is again the default window manager, but I could switch to Fluxbox with a single mouse click. Fluxbox is my current window manager of choice in Demudi, so I opted to work with it in Dynebolic too. Applications are accessed via the main display's pop-up menu, and the relevant categories include software for creating, editing, and playing video and audio content. Streaming media support comes from MuSE, a powerful application for audio mixing, encoding, and Internet broadcasting, written by Dynebolic's own jaromil.
Dynebolic's sound system is based on ALSA 1.0.11rc4 and JACK 0.100.0. The settings in QJackCtl are conservative but immediately usable. I reset the system to the same values as used in my tests of Apodio, with the same excellent results. One point of strangeness: I could not find the Envy24ctl mixer for my Delta 66, but fortunately the humble alsamixer utility worked perfectly to set the I/O channel volume levels for my card.
The applications menus show off a variety of multimedia programs and tools. The selection has been judicious, jaromil didn't just stuff everything he could find into his distro, and the included apps are all well-tested popular programs. If there's something missing you need only advise jaromil, or if you're the ambitious type you can just build it yourself.
I ran exactly the same tests as I ran for testing Apodio, with similar results. I experienced joy in my rambling improvisations with Jack Rack and Hydrogen, I recorded tracks of magnificence in Rosegarden, and I watched Ardour fail with the same reference to an illegal instruction. A note to packagers: Watch out for those pesky SSE instructions when compiling Ardour binary for use with an AMD Duron, they don't work on that CPU.
The great thing about live systems is that you just can't lose. Don't like the the system ? Reboot, try another one, repeat as neeed. However, I don't know how you can't like Dynebolic. It's engineered well, presented nicely, includes a good choice of applications, and it runs fast and smooth. Try it yourself, the cost is negligible (US$0.00) and you can keep your existing system pristine and untouched. Like I said, you can't lose.
By the way, if you don't already know, you can find links for all the software mentioned in this article at linux-sound.org. Many have colorful logos.
Next time maybe we'll look at some more live disc distros. Maybe I'll have those hard-disk recorders working here, and maybe I'll decide to write about something else entirely. You'll have to tune in to find out. Meanwhile, download Apodio and Dynebolic, have some creative fun and make some joyful noise.


Convert from Real-Life to Scale Size.
• Enter the Scale Factor, for 1/8th scale, enter 8.
• In the Real Size, enter the real-world size.
• Press, "Into Inch's" or "Into CM's " to select unit of measurement.
Convert from Scale Size to Real-Life.
• Enter the Scale Factor, for 1/8h scale, enter 8.
• In the Scale Size box, enter the measurement of a scaled object.
• Press, "Into Inch's" or "Into CM's " Same as above.
• Enter the original model's scale in the Middle (Scale to Real-life) calculator's "Scale Factor" box(24 for 1/24th scale).
• Enter the model's measurement in the Lower (Scale to Real-life) calculator's "Scale size" box (i.e. 6 inches).


text:
Q: MVC Application Loading Notifications I am going to be purchasing an MVC theme from WrapBootstrap https://wrapbootstrap.com/theme/inspinia-responsive-admin-theme-WB0R5L90S for a personal project.
There are alot of things that I like about it design wise, but it has brought up a question about the best way to load notifications in the header (really any sort of dynamic data that needs to load into the common Layout view).
I know there are a great number of ways to do this, but I am at the point in my development experience where I am trying to break my bad design habits (hacking things together so they "just work"), and look for elegant solutions where I can.
The things that make the most sense so far is to either:
1) Create a global ActionFilter that will filter all requests and throw a "LayoutViewModel" into the ViewBag, and just use the ViewBag in the _Layout view.

*

*I'd rather do something strongly typed, but I don't see a way.

*This is nice because it is available, does not require my controllers to inherit any functionality from a base class that might be cludgy, or even know that it is happening.

2) Load the page and onLoad, just do an Ajax Calls to the server to load any dynamic data I need.

*

*This may have some disadvantages if your layout needs to change based on the data.  I dislike with things snap all over the page after loading.

Is there a design pattern or MVC feature that I may be missing top accomplish this?
I may in the future I may implement something liks SignalR(or a simple timed ajax call to look for updates) to get updated data/notifications, but for now I am just looking at the initial page load.
Thank you for any ideas that you may have.

A: Most likely, what you're looking for is a child action. These are pretty much just like normal actions, except they'll return partial views and generally are decorated with [ChildActionOnly] to prevent routing to them via the URL bar.
[ChildActionOnly]
public ActionResult Notifications()
{
    var notifications = // get the notifications;
    return PartialView("_Notifications", notifications);
}

Then, in your layout, you just add the following where you want it to appear:
@Html.Action("Notifications", "Foo")

Where "Foo" is the name of the controller you put this child action in. I have a post on my blog that gives a primer on the Razor templating system that may be of use to you as well.

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ModernWell is a co-operative work, writing, and wellness space in Minneapolis. Whether you want to meet a friend, colleague, or client for a cup of coffee or tea; schedule a board meeting; listen to an inspiring speaker; or simply want to get out of your house or office to work on the novel you've always wanted to write, read the book that has been on your nightstand for months, or take a yoga class, ModernWell is your go-to oasis.
ModernWell is a haven for women who want to work, create, explore, and renew. ModernWell serves as a safe space for women to work independently or collaboratively and to be a part of an inspiring community of women who are intentional about aspiring to be their best selves and bring out the best in others.


Who doesn't want some more dice and some more roll? This game is going to give you exactly that. If you love the dice and roll and you have come to this game, then be sure you will not be disappointed. It is a classic game that is based on 5 reels and 40 pay lines. The symbols of this free slot machine game are all fruity. They are good on the eyes. You can turn this game to the auto play mode and dry your nail polish while rolling some cash in your pocket.
The only thing that is a slight less in this game is the grand jackpot. It is fixed at 15000 credits only. But it is also easier to win in than in any other slot machine game. The only thing this game does not have (that the original one had) is the big buck as the scatter symbol. But overall if you see it as a fresh one, it is a pretty good game.
More Dice and Roll is an online slot machine game from EGT that will make you intrigued in no time. The red colored dice is the wild symbol here and it does have many surprises in store for you. The 40 pay lines that are available in this game are all "fixed". This means that you get no option to tweak the pay lines. You will have to bet on all the lines. The heavy stakes player would really love this game that's why.
The dice symbols are the highest paying. But that is not all – they play a key role in steering your wins towards the right direction. Whenever it appears on the slot it will steer the icons in all directions, giving you bulk winnings. This means that if the symbol appears on the third reel, it will cover the entire fourth and fifth reel. With so many icons you would get a really nice share of the jackpot. Overall, it is quite a profitable game.


Surely we can see the handwriting on the wall. The time of the end is drawing near. Our world has embraced a degraded morality and a barren spirituality, fusing passions of the flesh with pleasures of fantasy. The Church of God must, in these final hours, take a final stand against the influx of evil.
From the three hundred Spartans at Thermopylae to Davy Crockett at the Alamo to the battle at Little Bighorn and Custer's last stand; the idea of a few against an overwhelming foe excites a fighting spirit within most and stirs up a winning attitude that can take on the world. And take on the world we must. For the world, and the God of it, is longing to rip apart everything we believe in to enter in and take over our territory. If we don't take a stand now, our opportunities to "save the lost", "do the great commission", "finish the work" will be gone.
As the popular saying goes "We must stand for something otherwise we will fall for anything." What are we, as the church of Jesus Christ, to stand for? In this new series of posts called "standing for something" I hope to highlight key beliefs that we are to stand for no matter the cost.
In this first post of several to come, I suggest one such stand which may seem obvious; the Bible. The Bible IS the Word of God! As such, the Bible is to be our rule, the one and only standard, for faith and practice. Everything that we believe and participate in ought to be grounded in the Word of God.
The Bible has been under attack from the beginning of its existence; yet it remains on various top sellers lists, such as the New York Times, and is one of the most revered and requested books around the globe. Renaissance authors and philosophers such as Voltaire and Gibbons spoke to the annihilation of the Bible (Wikipedia). Modern archeologists and historians are trying to discover "new" parchments and/or books which they claim debunk some or even add to the stories of the Bible. While these attacks are increasing and seemingly severe, the Bible has remained. What is it about the Bible that draws constant condemnation from its critics and constant commendation from its preachers? I suggest that those who condemn the Bible denounce it as a book, while we who lift up the Bible attribute it as so much more.
We must remember that the scriptures are the verbal inspiration of the Holy Spirit and that what is written is the voice of the Lord; it is the Logos (written word) and the Rhema (spoken word) [Logos and Rhema are Greek terms for the Word of God]. The Logos is liken to the personality of the Bible, giving characters to its stories and illustrations to its message. The Rhema is the charisma of the Bible, giving life and depth to the Logos. Rhema has two key parts, the active and the participatory. Active in Greek can be translated as energos, which hints to energy. The Rhema Word gives energy or power to the reader. As one reads the Bible, the Spirit of God actively speaks through the Words supplying this power to our inner spirit. Participatory is translated symmetécho̱. In the Greek, this word conveys the concept of symmetry and sharing. The Holy Spirit, in this way, shares our load while working with us, revealing His mind and direction. The Bible is more than just mere words on a page, it is something worth fighting for.
The Bible has the unique ability to go beyond the outer shell and see the real you. It is esteemed as the hallowed arbiter of what is right and what is just. It holds the distinctive of having a sacred and divine existence being called the Holy Scriptures. It is the living, tangible foundation upon which the Church is built and without which the Church would fall. It is the author and architect of a global faith that extends past man's endeavors and creeds. Its transforming power is a marvel to behold and its lasting worth is a supernatural wonder.
If we are going to stand for something, let us stand for the Word of God.


text:
Features, Food, News & Sports
THE NATURAL ALLERGY COMBAT PLAN
33rd ANNUAL WEST ALABAMA JURIED SHOW WILL TAKE PLACE AT THE BAMA THEATRE'S JUNIOR LEAGUE GALLERY
Arts, Entertainment, Features
Destihl Brewery //Wild Sour Series Blueberry Gose
Styx // "The Mission"
When the new Styx album, "The Mission," arrived last June, it ended a 14-year run without an album of new original material from the veteran band.
For years, the band members had debated whether there was any point to even doing a new album. As founding member James Young explained to this writer in a 2013 Interview, for veteran bands, many factors argue against making new albums.
Illegal downloading has cut into album sales to the point that it can be hard to make money on a new album. Radio only seems interested in playing the hit songs of veteran bands and resists spinning new tunes. And doing a new album, in the case of Styx, would mean taking time away from touring, which is now the band's main source of income, and losing personal time the band members could spend with their families and friends – something that is limited for a band like Styx that plays some 125 shows a year.
But guitarist/singer Tommy Shaw, the band member who was the catalyst in creating "The Mission," said this was a project that just seemingly demanded to happen.
"You know, (it's like) when you're doing something new and you're wondering am I doing the right thing. Is this insane?" Shaw said. "A lot of times life will give you a warning to say this is crazy. Stop now. Or, you'll see signs that just come out of nowhere that say I think we're going in the right direction. And this kept happening."
"The Mission" was not a product of extensive forethought, band meetings and planning. According to Shaw, it literally began with a few musical notes he played about two years ago.
"We were on the road and I wrote this little riff. And if you listen to the album, it's the very last song on the album ("Mission to Mars")," he said. "I wrote the beginnings of that on the road, a little riff and some chords. I took it home and I laid it out in a Pro Tools file and I wrote the little middle section to it. Then it was like 'Well, I'm anxious to sing it.' It's going to need some words so I can sing it. So I sat down and I wrote the lines 'Now I can say it/This is the day/ We'll be on our way/ On our mission to Mars.' And I wrote that down because the song has this kind of upbeat, kind of joyful vibe to it…And so that's what I wrote, and it was like where did that come from? It's just what came out."
Shaw said he liked the feeling of excitement and anticipation of those words, but he then wrote a more cautionary set of lines for the middle section, which brought a whole different dimension to the song and triggered him to start thinking in much bigger terms about where his little burst of inspiration might
take him.
"The middle section was a left turn," Shaw said. "That's where the idea came into my head that this is really about the individuals, the human beings that are on that mission, what they're going through. It's very exciting and everything, but when they strap in on that rocket, they're getting ready to leave everything and everyone, all the things they ever knew, they're leaving it behind and they may never return. And that right there, that's the human situation and humans going through these life-altering situations. That's something that Styx is good at, is writing about people going through life. All of a sudden it became not just this fun little thing. All of a sudden it took on a (sense of) 'Wait a minute, there might be something here.'"
From there, Shaw teamed up with songwriting collaborator/producer Will Evankovich – and before long, Styx keyboardist/singer Lawrence Gowan — to continue exploring the emerging album until the trio was ready to propose doing the album to other band members (Young, drummer Todd Sucherman, bassist Ricky Phillips and occasional concert guest star and original bassist Chuck Panozzo.)
"If I had just gone to them with one song and said 'Hey, I've got this song about a mission to Mars. Let's do a record,' if they had said that to me, I would have gone 'Eh, really? Are you sure?'" Shaw said. "So Will and I went to great lengths to make sure the pieces we had sounded like a finished record so you didn't have to imagine it. You could listen to it and go 'Wow, this really sounds good.' So by the time they heard it, it was a really good demo for a new Styx album. That was when everybody thought this is for real."
Eventually "The Mission" turned into a story that chronicled the ups and downs of the first mission to Mars in 2033, with Styx's three vocalists each singing the parts of a character in the story (Shaw as the pilot who likes living life by the seat of his pants, Gowan as the first officer who brings a big brother personality to the mission and Young as the engineer who must be satisfied with the technical workings of the mission).
But while the story is futuristic, the music on the album is very much old school, classic Styx – something that was very much a goal for "The Mission." The band's signature mix of hard-charging guitar rock and hooky pop (mixed with a bit of progressive rock and plenty of backing vocals and harmonies) is very much intact, as the new album weaves together concise hard-rocking tracks like "Gone Gone Gone" and "The Outpost," the grooving pop-soul of "Hundred Million Miles" and more multi-faceted prog-ish tracks like "Locomotive," "Time May Bend" and "Radio Silence."
Styx's sound has certainly worked for the band. After building a sizable grass roots following – especially in the Midwest – the band broke through in a big way in 1977 with "The Grand Illusion." Then like that signature album, Styx's next three studio albums — "Pieces of Eight" (1978), "Cornerstone" (1979) and "Paradise Theatre" (1981), also topped two million copies sold before the band's momentum started to stall. Over the next decade, the band broke up a pair of times in the '80s and early '90s and went through a series of personnel changes, the biggest of which was replacing original singer/keyboardist/songwriter Dennis DeYoung in 1999 with Gowan. The current band lineup, though, has stayed intact since 2003, and Styx has returned to being a strong draw on the concert circuit.
The band's many hits (such as "Come Sail Away," "The Best of Times," "Blue Collar Man" and "Too Much Time on My Hands") remain the foundation of its live shows, and Shaw said the band has been careful about adding songs from "The Mission" into its live set, noting that "Gone Gone Gone" was the only new song in the set prior to the album's release.
"We crash into it kind of the same way it does on the album," Shaw said, adding that now that fans are able to hear "The Mission" the group seeing how fans are responding to help decide which new songs to add to the set. "That will help determine if we add any more to our set."
concertsmusicstyx
Barbecue The History of an American Institution by Robert F. Moss
Chris Young talks about his journey, and safety issues in the concert arena!
MATTHEW ASHRAF // Former HBCU student talks about performing with Beyoncé,

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You don't have to have a PayPal account to Check out, to pay with a credit card look on the right side of the Check out screen, or you may phone in your order at (409)656-3013.
This Strip Stick is designed for pressing needs when in small, compact areas, such as classrooms, quilting retreats, etc, or for smaller projects such as quilt blocks. Includes plastic cover when not in use.
Fat Quarter Strip Stick 22 1/2"
This Strip Stick is designed for pressing Fat Quarter strips when cut along the long side, and for using in small, compact areas, such as classrooms, quilting retreats, etc, or for smaller projects such as quilt blocks. Includes plastic cover when not in use..
This Strip Stick (the original) is designed to use when pressing longer seams in strip quilting, but does not fold. It is useful in your sewing area and fits comfortably on your ironing board. Includes plastic cover when not in use.
Gives you cool white light (400 lumens) where you need it. Easy to setup. Includes a Dimmer/On/Off switch so you can adjust the brightness.
the Long Arm Extension Kit.
You don't have to have a PayPal account to Check out, to pay with a credit card look on the right side of the Check out screen, or you mayphone in your order at (409)656-3013.
The best oiler made, no leaks or drips. The precision Oiler is a highly accurate lubrication tool intended for anyone working with small mechanical parts. The needlepoint tip allows for the precise placement of oil on sewing machines and sergers. The smooth thumb actuator lets you control the release of lubricant from the reservoir in small droplets. It has a protective screw-on cover prevents leakage.
Texas sales tax will be added to orders if bought and shipped to an address in Texas.


If your credit rating is very low or you have CCJs against you or have even got into arrears then getting someone to say "yes" to giving you a loan can be next to impossible. While your circumstances might dictate that you can't get a personal loan, there are other options and one of them is taking out an adverse credit loan.
An adverse credit loan is one option and while a loan of this type usually comes with a higher rate of interest, if you have to take out a form of borrowing, then it should be worthwhile considering.
Even though an adverse credit loan will have a higher rate if you go with a specialist website you will be assured of getting the best possible rates of interest available for your circumstances.
Your credit rating and credit score is one of the main factors that are taken into account and if you have had problems in the past with your finances then it will have affected your credit score. If your score is too low then the majority of lenders see you as too big a risk and so turn you down when you apply. An adverse credit loan is particularly aimed at those with problems with credit.
A specialist website will shop around on your behalf with lenders that specialise in adverse credit loans and get the quotes for you which you can then compare and decide if this type of loan is suitable for your circumstances. Along with getting quotes they will also be able to give you the information you need to understand the loan and the key facts of any particular policy that you are considering taking out. Always make sure you read the small print as this is where the terms and conditions of the loan are and is where you can find the total amount repayable along with the monthly terms of the loan.
There are many high limit credit cards available right now over the net. I recently applied for a Bank of America card and was given a $5,000 limit. I was then able to consolidate my other cards into that one which brought my credit score up several points. The balances that I transferred were on an introductory offer where I wasn't even required to pay interest until next year so I saved hundreds of dollars just by doing that transaction. Then since my credit score had gone up I applied, (online again) for a one click balance increase request and was given another $5,000 that I needed to pay business expenses. The increase was given without any hassle from bank accountants and I wasn't bothered with any other offers. So now my credit score is higher than it has ever been and I have put much more experience on my history that will help when it's time to apply for a larger loan.
I say all of this to show that online banking with high interest credit cards can be very rewarding if used responsibly. Many people see credit card offers and run away not realizing that they could probably pay off all their current cards in half the time by consolidating. I actually think the low limit cards with high interest rates cause consumers to get in more trouble because they don't have time to catch up before the entire balance is exhausted.
The Bank of America card isn't the only excellent offer available online though. There are many others. One of my other favorites is the Discover more card which started me off with a $4000 limit. This card also has excellent customer service in my opinion, on and offline.
10,000 Star points bonus with first purchase enough for up to three free nights(1)Double Star points on stays at participating Star wood Hotels & Resorts and purchases at select Starwood retail outlets, such as Bliss Spa and more(2)Automatic upgrade to Gold Preferred Guest membership status by spending $30,000 on the Card in each calendar year. Access to private sales with select Starwood retail outlets.The new Business Card incorporates all of the improved benefits of the Starwood Preferred Guest Credit Card, as well as programs and services tailored specifically to the needs of small business owners, including the OPEN Savings(SM) program which was designed specifically for small businesses and gives automatic discounts on purchases at OPEN Savings(3) partners, such as Delta, FedEx Kinko's and JetBlue. In addition, the Business Card provides expense management reporting, an online spend tracking system and spending limits on additional cards that aid in better managing employee spending.
So don't be scared to apply for a high limit card, just be responsible. One thing I always check is the annual fee. Most of the cards that will be of benefit to you do charge an annual fee. Of course there are always exceptions to the rule. If the card has an annual fee and the interest rate is extremely low then it might actually be a better offer in disguise,but i would still read the fine print. You can check out some of the offers in the link below. I guarantee you'll save alot of money in the long run.
All rights reserved. Article may be reprinted as long as the content remains intact and unchanged and all links remain active.
Sometimes things come up that are out of our control and we need to use a credit card for the purchase because we don't have the cash on hand. Other times, we just have to have the latest toy or gadget and use a credit card to buy it. But when the bill comes due, it can be unpleasant.
If things get too out of hand, we can be left with a large credit card debt and no easy way to pay it down. We end up paying a ton of interest, sometimes for years after the purchase was made. Fortunately there are places to turn to if you have a credit card debt problem.
The first step to take is to try and get a lower interest rate on your card. This can be done in either of two ways. The first – and probaby simplest – way is to call your credit card provider's customer service number and ask for a lower rate.
They'll tell you within seconds if you qualify for a better rate or not, and you'll be surprised at how often you will get it simply by asking.
The second way you can get a better rate is by applying for a new card that has a better interest rate than your current one. You can then transfer the balance from the higher rate card onto the lower rate one and save the difference in interest.
Credit Counseling is another option for managing your credit card debt. There are many credit counseling services that can help you work with your current creditors to get a better rate and more reasonable repayment schedule. These services deal with the credit card companies on a regular basis, so they can often succeed where you might not if you call them yourself.
In many cases, credit counseling is a free service – you don't have to pay anything, or if you do it's a minimal charge. You'll need to have all your credit card information ready for them, as well as a list of all your creditors and balances with each.
They can take that information and work out the most effective payment schedule for your particular situation. If you're feeling overwhelmed by credit card debt, don't keep struggling to stay on top of it. Talk to a credit counseling service and start to get ahead again.
The unfortunate reality for many Americans is large credit card debt. Savvy advertisers have convinced us to buy things that we don't need and we've spent and spent without any idea about the kind of debt we are racking up. College educations can be expensive and then comes a house and family and next thing we know we are deeper in debt then we've ever imagined. If you want a better life for you and your family then you will want to eliminate high-interest credit card debt and get your life in order. Try eliminating debt once and for all if you really want to clean up your act. Staying away from bankruptcy and learning good debt management can be tough, but worth it. There are different ways to think about ending your debt, it's never too late to star.
It's a give that we all want to get out of credit card debt as fast and painlessly as possible, but the real question is how do we get started on that road today? This can be a hard question for some people, but the answer can be easy depending on your credit situation and how your debt is spread out over your credit cards. Your current interest rates are also a factor in the decision of how to get out of debt. The first thing to do is to write down all your creditors and the amount of debt accrued through each card, as well as the interest rates you are paying. Once you have all the information in front of you, then you can hit the Internet to find the best deal for your debt consolidation.
When you are searching for the best way to consolidate debt the key you want to keep in mind is how low can you the interest rate. You want to choose the plan that will consolidate your debt into one affordable monthly rate, while also giving you a great interest rate. You could choose to transfer the balance of your credit cards onto one lower interest or no interest credit cards. Many cards offer an introductory zero interest plan so you only pay the minimum for six months or a year before the interest rate kicks in.
Sometimes it can take months or years to get out of credit card debt, but the most important thing is to make sure you can make your monthly payments reasonable enough to live with. With the help of the internet you are sure to find many great choices to help you eliminate credit card debt for good!


PROFILE | When Yoweri Museveni's 'liberators' stormed and overran Kampala on January 26, 1986, before announcing the fundamental change the following day, there were certainly many Phiona Mirembes in Uganda, especially in Busoga where the botanical name Mirembe is common, but there wasn't Phiona Mirembe, the daughter of Rose and Daniel Bawuna.
The Bawunas, from Kamuli District in eastern Uganda, presumably had seven children at the time, but Mirembe would arrive just in time to be alive when Museveni celebrated two years of NRA Liberation Anniversary.
The former guerilla leader has since served for 33 years while Phiona will only be as many years old in 2021 when Ugandans go to polls with, possibly, herself on offer as a candidate seeking to succeed Museveni in a democratic transition.
Single and with no political encumbrances, Mirembe has decided to throw her hat in the usually heated presidential race that has over the last 20 years been defined by Museveni-Besigye rivalry with many also-ran candidates trailing with measly vote percentages.
Mirembe's decision, announced on her social media handle and confirmed to Crime24 later, will unlikely turn many heads around in a race that Museveni is expected to lead again. But to family, the decision comes as a bit of a shocker.
In May 2018, Mirembe suffered a professional hiccup that prolonged into a cancer. The baby she had birthed on August 26, 2014, and proudly named 'Mirembe and Company Advocates' suffered a deadly strain of apnoea. She had to close down the law firm that had stopped breathing.
"It was the 18th of June 2017 when I cried the last and most painful tear for my law firm. By just one email, a fee note of $20 million (about Shs70 billion) that I had worked extremely hard for melted in my hands; debt of over Shs900 million loomed over my head. It was huge, to date I still struggle to find words to explain it all to anyone properly," Mirembe said recently.
After a year out, Mirembe reopened for business in May 2018 with new premises on Plot 8 Upper Naguru Road on Naguru Hill, a bit of an affluent location compared to the weather-beaten one before. How she managed to pick up the pieces and revive the firm is a lesson she wants to hold dear.
From crying and drying up the cheek to living the unfeasible dream of the presidency, that is what a year has made Rose and Daniel Bawuna's daughter.
Born in a family of 12 siblings, Mirembe went to Stella Maris Nsuube in Nkokonjeru and sat PLE in 1999 before going to far-east at Tororo Girls School that she later swapped for Lugazi Mixed Secondary School for her Ordinary Level education.
She completed Advanced Level from St Mary's Boarding Secondary School, Kitende, and joined Makerere University from where she graduated with a Bachelor of Laws degree in 2010.
During Post Graduate Diploma in Legal Practice from Law Development Centre between 2011 and 2012, Mirembe clerked with Shonubi, Musoke & Co. Advocates where she honed her skills in legal practice and picked tidbits on how to run a firm.
"After LDC, I opened a limited liability company called Burkley Consults Limited on November 12, 2012, from which I got the idea to start my own firm," she says.
And now Mirembe feels she has come far enough to wash her hands and join the political tough muscles at the dining ballot box where, barring some strange occurrences, incumbent Yoweri Museveni will seek re-election on NRM ticket.
"I'm of the opinion that Uganda is in a state of rot, everything is rotten. You need someone to help you out of a ditch of rot and I believe the person to help Uganda out of the rot is going to be God Himself. I will do my part to stand up and be counted, and I'll let God do what o can't do," she said.


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Sie sind hier: Armed Actors / Civilians
1: State Security Forces.
2: Civilians.
3: Private Security Companies.
4: Armed Groups.
5: Gangs.
Mapping Murder: The Geography of Indian Firearm Fatalities, September 2011. India Armed Violence Assessment Issue Brief No. 2 (also available in Hindi).
Estimating Civilian Owned Firearms, September 2011. Research Note No. 9, Armed Actors (also available in Catalan and Spanish).
Balancing Acts: Regulation of Civilian Firearm Possession, by Sarah Parker, 2011. In Small Arms Survey, Small Arms Survey 2011: States of Security.
File 10 to 12 out of 51
First < Back Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 Page 10 Next > Last
Civilians who possess small arms include collectors, hunters, sports shooters, individuals fearing for their personal security, and criminals. Private ownership of firearms, both legal and illegal, accounts for about 85 per cent of the global small arms stockpile. National legislation generally restricts the types of weapons legally available to civilians. In several countries, however, private individuals can access fully automatic firearms legally. Another concern lies in the extent to which the availability of firearms to the general population influences levels of armed violence – including the occurrence of homicides, other types of armed crime, and suicide.
The Small Arms Survey keeps track of civilian ownership of small arms worldwide, both registered and unregistered. Household surveys and focus group discussions undertaken in a number of settings have made it possible to refine knowledge on individual motivations for resorting to gun ownership, their perceptions of small arms, and the effectiveness of policies to address uncontrolled arms proliferation. The Survey also examines key questions related to the civilian ownership of small arms, including the links between arms regulation and violence levels, the demographic profile of arms bearers, national firearms regulations, and the effectiveness of initiatives to collect civilian firearms.
Small Arms Survey Publications
File 301 to 51 out of 51
File 301 to 6 out of 6
UK Home Office: Firearms Certificates, England and Wales
US Bureau of Alcohol, Tobacco, Firearms and Explosives: Annual Firearms Manufacturing and Export Report


Should be mandatory its watching before posting a word on the forum......maybe this needs to be done before you contact ADMIN for reinstatement..
I reckon there is no difference between what is and what should be.
You reckon wrong Russ.....what gaurinathan/CV/Nathan is doing is an aberration of the WMM......why settle for anything less but the real thing.
There is no expression that is wrong.
It is entirely possible that an expression may be a mistake, mistakes are never wrong.
Mistakes are the learning mechanism of MEST.
Regarding the expressions of "gaurinathan/CV/Nathan", I have no doubt in the sincerity of their desire to synthesise the way in which individuals may learn to discern how to integrate "The Materials".
The WingMaker materials, initially meant for the few that sensed their fragrance, are now being made available to a wider audience.
THIS......this is part of the plan.
from my perspective it is an abomdamnation of the WMms ... its really creepy - intentionally ... by design - as if to repel - not to forget the "tone" ... and the language.
Russ your Heart may be in the right place but your mind is another story if you think that gaurinathan/CV/Nathan 's youtubes are helping the WM cause..... and reminds me of the" help "Paul gave Jesus....the Materials stand by themselves they do not need his changes.....Paul's seeds altered the message of Christ and helped spawned the Church of Rome....hard for me to believe that down deep this is something you would like to see come of the WMM.....Nat on the other hand I do believe would love to headline a following....and is willing to do whatever it takes to fulfill this desire he has within himself.
Well, I would say that "gaurinathan/CV/Nathan 's youtubes" are a TZ.
......Tributary Zones will become the new religion......They will become the touchstone for accessing the new energy coming into the planet as a result of the Grand Portal's discovery.
In this time, the new structure of the Hierarchy will -- like a glove turned outside in -- finally fit the "human hand".
This will herald the Return of the Masters who have remained behind the veil of secrecy because of the survival-based interests of religion, business, government, and science.
Hmm....must admit that I see what you are saying Russ.... and i certainly think it possible that one could come to the WMM via these youtubes that are still to me an aberration .....my children when they were young loved to eat at MacDonalds....but as they have gotten older and their palates more developed....they do not.....am hoping those that like Nat's tubes have the same growth.
Don't forget, these youtubes (unlike fast food), just like the WMM, are free to all; in that respect, they are on a par.
As a medium for reshuffling one's mental deck, they too are equal to and level with.
gaurinathan/CV/Nathan is not the topic here Russell ... he isn't affiliated with the WMms anymore than any of the others who stole and distorted the WMms ... just smaller because he can't even afford his own forum (snicker) ... The only people who find his vids anything more than an attempt to associate himself with the WMms are deceiving themselves ... James is the Avatar of the WMMs ... not Nat - for obvious reasons he is not capable of even discussing the materials much less modifying them to suit his agenda to be a "savior" .
give it a rest Russell, if the only reason you come to this forum is to spam Nats krap - please consider not coming anymore because there is no one left here that appreciates it ... in fact the ones who are left see it for what it is ... self promotion of false teachings and half-truths to deceive others into supporting him... obviously you are the only one here now, who isn't able to discern that .


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Double French Version. Double Black Vinyl with discobag inner-sleeves in gatefold sleeve. 30x60cm French version poster. French CD version included.
Release Date: September 21st 2018
Album of the Month - October 2018
Christine and The Queens' new album Chris. Available here on Deluxe Four-LP Edition, English Version Double LP, French Version Double LP and Double CD.
This is the second album from Héloïse Letissier and it's available in French or English. It was produced in Paris and LA and is written, arranged and performed by Christine and The Queens.
These are songs celebrating Christine's polysexual desire without sidelining her emotional pain. Rigid irresistible disco beats commanding a dancing rhythm reaction from feet and minds swaying while sultry pop vocals swoop and glide garnished by divine harmonies. Super slick funked up moody beats make subtle shifts and gyrate in spriallying song of desire and pain.
Christine and The Queens release her eagerly anticipated second album. Titled Chris, the record is released by Because Music, including double CD and vinyl versions, as well as limited edition boxset, There are two versions of the album; one sung exclusively in English and one sung exclusively in French. Chris was written, arranged and performed by Christine and the Queens. It is the follow up to her already-iconic debut record Chaleur Humaine, released to near-universal acclaim in France in 2014 and the UK in 2016, and selling more than 1.3 million copies to date.
ROUGH TRADE RADIO SPECIAL
Listen to a very special playback of Rough Trade and Because Present Christine and the Queens in conversation!
Chris, AKA Héloïse Letissier, spoke to host Miranda Sawyer and answered audience questions at a very special event at Soho Curzon on 16th September 2018, to celebrate the release of her second album 'Chris' via Because Music.
LPx4 - Deluxe Edition Four-LP.
LPx2 - Double English Version. Double Black Vinyl with discobag inner-sleeves in gatefold sleeve. 30x60cm English version poster. English CD version included.
LPx2 - Double French Version. Double Black Vinyl with discobag inner-sleeves in gatefold sleeve. 30x60cm French version poster. French CD version included.
CDx2 - Double CD in 3-panel softpack with 28-page stapled booklet. Contains English and french Versions of the album.
CD - Standard CD
Label Because Music
Genre Rock-Pop
Featured in: Pitchfork's Albums of the Year, Albums of the Year 2018, Albums of the Month - October 2018
More from Because Music
Clandestino, title
Manu Chao , artist
The English Riviera, title
Metronomy , artist
Madjafalao, title
Le Tout-Puissant Orchestre Poly-Rythmo , artist
Summer 08, title


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Concept: Autophagy
The RAB GTPase RAB18 modulates macroautophagy and proteostasis
Biochemical and biophysical research communications
Macroautophagy is a conserved degradative pathway and its deterioration is linked to disturbances in cellular proteostasis and multiple diseases. Here, we show that the RAB GTPase RAB18 modulates autophagy in primary human fibroblasts. The knockdown of RAB18 results in a decreased autophagic activity, while its overexpression enhances the degradative pathway. Importantly, this function of RAB18 is dependent on RAB3GAP1 and RAB3GAP2, which might act as RAB GEFs and stimulate the activity of the RAB GTPase. Moreover, the knockdown of RAB18 deteriorates proteostasis and results in the intracellular accumulation of ubiquitinated degradation-prone proteins. Thus, the RAB GTPase RAB18 is a positive modulator of autophagy and is relevant for the maintenance of cellular proteostasis.
Concepts: Fibroblast, Modulation, ACT, GTPase, Autophagy
Autophagosome closure requires membrane scission
During the intracellular process of macroautophagy (hereafter autophagy), a membrane bound organelle, the autophagosome, is generated de novo. The remodeling of the autophagic membrane during the lifecycle of the organelle is a complex multistep process and involves several changes in the topology of the autophagic membrane. Here, we focus on the final step of autophagosome formation, the closure of the phagophore, during which the inner and outer autophagic membranes become separate entities. We argue that this topological membrane transformation is a membrane scission event. Surprisingly, not a single recent review describes this substep as membrane scission (or membrane fission). In contrast, a number of publications imply that membrane fusion is involved. We discuss the potential sources for misinterpretation and recommend to consistently use the unambiguous term "membrane scission".
Concepts: Mathematics, Cell membrane, Organelle, Geometry, Biological membrane, Metric space, Closed set, Autophagy
A missing piece of the puzzle: Atg11 functions as a scaffold to activate Atg1 for selective autophagy
The mechanism regulating Atg1 kinase activity for the initiation of selective macroautophagy (hereafter autophagy) under nutrient-rich conditions has been a long-standing question. Canonically in yeast, nutrient starvation or rapamycin treatment repress TOR complex 1 and stimulate the Atg1 complex (including at least Atg1, Atg13, Atg17, Atg29 and Atg31), which allows the recruitment of downstream autophagy-related (Atg) components to the phagophore assembly site (PAS), culminating in phagophore formation, and, subsequently, autophagosome biogenesis. Atg1 also functions under conditions promoting selective autophagy that do not necessarily require nutrient deprivation for induction. However, there has been some debate as to whether Atg1 catalytic activity plays a more important role under conditions of nutrient starvation-induced autophagy (i.e., bulk autophagy) versus selective autophagy (e.g., the cytoplasm-to-vacuole targeting [Cvt] pathway). A recent paper by Kamber and colleagues investigates the mechanism regulating Atg1 activity during selective autophagy.
Concepts: Enzyme, Catalysis, Protein kinase, Catalytic converter, Nitrogen, Chemical equilibrium, Initiation, Autophagy
Role of autophagy in IL-1β export and release from cells
Seminars in cell & developmental biology
The autophagy pathway known also as macroautophagy (herein referred to as autophagy) is characterized by the formation of double-membrane organelles that capture cytosolic material. Based on pathway termination alternatives, autophagy has been divided into degradative and secretory. During degradative autophagy, autophagosomes typically fuse with lysosomes upon which the sequestered material is degraded. During secretory autophagy, instead of degradation the sequestered cargo is subjected to active secretion or passive release. In this review, we focus on the mechanisms of secretion/passive release of the potent pro-inflammatory cytokine IL-1β, as a prototypical leaderless cytosolic protein cargo studied in the context of secretory autophagy.
Concepts: Cell nucleus, Cell, Mitochondrion, Cytosol, Golgi apparatus, Organelle, Endoplasmic reticulum, Autophagy
Trehalose Accumulation Triggers Autophagy during Plant Desiccation
PLoS genetics
Global climate change, increasingly erratic weather and a burgeoning global population are significant threats to the sustainability of future crop production. There is an urgent need for the development of robust measures that enable crops to withstand the uncertainty of climate change whilst still producing maximum yields. Resurrection plants possess the unique ability to withstand desiccation for prolonged periods, can be restored upon watering and represent great potential for the development of stress tolerant crops. Here, we describe the remarkable stress characteristics of Tripogon loliiformis, an uncharacterised resurrection grass and close relative of the economically important cereals, rice, sorghum, and maize. We show that T. loliiformis survives extreme environmental stress by implementing autophagy to prevent Programmed Cell Death. Notably, we identified a novel role for trehalose in the regulation of autophagy in T.loliiformis. Transcriptome, Gas Chromatography Mass Spectrometry, immunoblotting and confocal microscopy analyses directly linked the accumulation of trehalose with the onset of autophagy in dehydrating and desiccated T. loliiformis shoots. These results were supported in vitro with the observation of autophagosomes in trehalose treated T. loliiformis leaves; autophagosomes were not detected in untreated samples. Presumably, once induced, autophagy promotes desiccation tolerance in T.loliiformis, by removal of cellular toxins to suppress programmed cell death and the recycling of nutrients to delay the onset of senescence. These findings illustrate how resurrection plants manipulate sugar metabolism to promote desiccation tolerance and may provide candidate genes that are potentially useful for the development of stress tolerant crops.
Concepts: DNA repair, Climate, Weather, Climate change, Programmed cell death, Solar variation, Thermohaline circulation, Autophagy
Autosis and autophagic cell death: the dark side of autophagy
Cell death and differentiation
It is controversial whether cells truly die via autophagy or whether - in dying cells - autophagy is merely an innocent bystander or a well-intentioned 'Good Samaritan' trying to prevent inevitable cellular demise. However, there is increasing evidence that the genetic machinery of autophagy may be essential for cell death in certain settings. We recently identified a novel form of autophagy gene-dependent cell death, termed autosis, which is mediated by the Na(+),K(+)-ATPase pump and has unique morphological features. High levels of cellular autophagy, as occurs with treatment with autophagy-inducing peptides, starvation, or in vivo during certain types of ischemia, can trigger autosis. These findings provide insights into the mechanisms and strategies for prevention of cell death during extreme stress conditions.Cell Death and Differentiation advance online publication, 26 September 2014; doi:10.1038/cdd.2014.143.
Concepts: DNA, Protein, Gene, Genetics, Gene expression, Organelle, Programmed cell death, Autophagy
The IAP family member BRUCE regulates autophagosome-lysosome fusion
Autophagy has an important role in cellular homeostasis by degrading and recycling cytotoxic components. Ubiquitination is known to target cargoes for autophagy; however, key components of this pathway remain elusive. Here we performed an RNAi screen to uncover ubiquitin modifiers that are required for starvation-induced macroautophagy in mammalian cells. Our screen uncovered BRUCE/Apollon/Birc6, an IAP protein, as a new autophagy regulator. Depletion of BRUCE leads to defective fusion of autophagosomes and lysosomes. Mechanistically, BRUCE selectively interacts with two ATG8 members GABARAP and GABARAPL1, as well as with Syntaxin 17, which are all critical regulators of autophagosome-lysosome fusion. In addition, BRUCE colocalizes with LAMP2. Interestingly, a non-catalytic N-terminal BRUCE fragment that is sufficient to bind GABARAP/GABARAPL1 and Syntaxin 17, and to colocalize with LAMP2, rescues autolysosome formation in Bruce -/- cells. Thus, BRUCE promotes autolysosome formation independently of its ubiquitin-conjugating activity and is a regulator of both macroautophagy and apoptosis.
Concepts: Proteins, Protein, Protein structure, Mitochondrion, Organelle, Posttranslational modification, Programmed cell death, Autophagy
Autophagy Controls the Kinetics and Extent of Mitochondrial Apoptosis by Regulating PUMA Levels
Cell reports
Macroautophagy is thought to protect against apoptosis; however, underlying mechanisms are poorly understood. We examined how autophagy affects canonical death receptor-induced mitochondrial outer membrane permeabilization (MOMP) and apoptosis. MOMP occurs at variable times in a population of cells, and this is delayed by autophagy. Additionally, autophagy leads to inefficient MOMP, after which some cells die through a slower process than typical apoptosis and, surprisingly, can recover and divide afterward. These effects are associated with p62/SQSTM1-dependent selective autophagy causing PUMA levels to be kept low through an indirect mechanism whereby autophagy affects constitutive levels of PUMA mRNA. PUMA depletion is sufficient to prevent the sensitization to apoptosis that occurs when autophagy is blocked. Autophagy can therefore control apoptosis via a key regulator that makes MOMP faster and more efficient, thus ensuring rapid completion of apoptosis. This identifies a molecular mechanism whereby cell-fate decisions can be determined by autophagy.
Concepts: DNA, Death, Organelle, Effect, Apoptosis, Programmed cell death, Autophagy
Cargo recognition and degradation by selective autophagy
Nature cell biology
Macroautophagy, initially described as a non-selective nutrient recycling process, is essential for the removal of multiple cellular components. In the past three decades, selective autophagy has been characterized as a highly regulated and specific degradation pathway for removal of unwanted cytosolic components and damaged and/or superfluous organelles. Here, we discuss different types of selective autophagy, emphasizing the role of ligand receptors and scaffold proteins in providing cargo specificity, and highlight unanswered questions in the field.
Concepts: Cell nucleus, Cell, Signal transduction, Organelle, Ribosome, Cell biology, Receptor, Autophagy
Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy
Cellular and molecular life sciences : CMLS
Mitochondria are an essential source of ATP for cellular function, but when damaged, mitochondria generate a plethora of stress signals, which lead to cellular dysfunction and eventually programmed cell death. Thus, a major component of maintaining cellular homeostasis is the recognition and removal of dysfunctional mitochondria through autophagy-mediated degradation, i.e., mitophagy. Mitophagy further constitutes a developmental program, and undergoes a high degree of crosstalk with apoptosis. Reduced mitochondrial quality control is linked to disease pathogenesis, suggesting the importance of process elucidation as a clinical target. Recent work has revealed multiple mitophagy programs that operate independently or undergo crosstalk, and require modulated autophagy receptor activities at outer membranes of mitochondria. Here, we review these mitophagy programs, focusing on pathway mechanisms which recognize and target mitochondria for sequestration by autophagosomes, as well as mechanisms controlling pathway activities. Furthermore, we provide an introduction to the currently available methods for detecting mitophagy.
Concepts: Cell, Adenosine triphosphate, Organelle, Apoptosis, Prokaryote, Computer program, Programmed cell death, Autophagy


The purpose of this document is to answer questions about Service and Contract Billing Questions related to intercompany or multiple company set up.
Question 1: The GL Offset designated in the Customer Master (P03013) is set up in the AR Trade Automatic Accounting Instruction (AAI) to a different company, however, the Accounts Receivable Invoice is still associated to the original company. Is it possible to set up Service Billing Invoice Generation (R48121) to generate the AR Trade GL account ( RCxxx AAI) and AR Service Billing Invoice to a different company?
Question 2: If a contract is set up with multiple jobs in the Billing Line Detail (F5202) that are from various companies, when the invoice is processes and posted to the GL the revenue goes to the specific job but the Accounts Receivable and A/R Retainage is posting to the company of the job from the Contract Master (P5201). Is it possible for the A/R to post to the same company to which the job belongs?
Question 3: Is it possible to create a Zero Dollar Invoice when selecting Create AR (R48199) from Batch Review (P48221)?
Question 4: Is it possible to change an Accounts Receivable record (F03B11) in the Standard Invoice Entry (P03B2002) that has been created in Contract or Service Billing?
Question 5: When populating the 2nd processing option with a blank to use the system date, BA documents still use the original document date. Why is this occurring and what is the workaround?
Question 6: When running the Invoice Generation (R52121) the batch is out of balance. What tables need to be reviewed and/or compared to verify the issue?
Question 7: Receiving error on R48131 missing 4811 AAI and Tax Authority Not Valid. How is this related to the DMAAIs? How can this be resolved?
Question 8: When running Invoice Generation (R48121) calling Journal Generation (R48131), G/L Distribution errors were noted, how can the batch be updated once the errors are corrected?
Question 9: When running Create AR (R48199) the subledger value is not being populated on the F03B11 or F0911 as designated in the setup. What needs to be changed?
Question 10: What AAIs are needed for Revenue Recognition Journal Creation (R48132) are needed for creation of batch?
Question 11: After adding a new AAI using Billing AAIs (P48S95), the AAI appears to be a header only (Bold) and does not allow me to add specific G/L account for the AAI. How do I resolve this?


Violinist, conductor, and historian Robert Whitehouse Eshbach is an honors graduate of Yale University (BA), where he majored in music history and minored in German literature. He studied violin at the Vienna Conservatory (now the Konservatorium Wien Privatuniversität) with Walter Barylli, concertmaster of the Vienna Philharmonic and State Opera Orchestras, and earned a Master of Music degree in violin at New England Conservatory, studying with Eric Rosenblith. He studied music history with, among others, Alejandro Planchart, Robert Bailey, Frank D'Accone, William Waite, Claude Palisca and Daniel Pinkham, and German literature with Cyrus Hamlin, Jeffrey Sammons, and Peter Demetz. His recent publications and invited papers have focused on nineteenth-century musicians: Joachim, Brahms, Mendelssohn, Schumann, Reinecke, Ede Reményi, and Wilhelmine Norman-Neruda (Lady Hallé). His article, "Joachim's Youth — Joachim's Jewishness," was published in the Winter 2011 issue of The Musical Quarterly. His chapter "The Joachim Quartet Concerts at the Sing-Akademie zu Berlin: Mendelssohnian Geselligkeit in Wilhelmine Germany" appeared in the volume Brahms in the Home and the Concert Hall: Between Private and Public Performance, Katy Hamilton and Natasha Loges (eds.), Cambridge University Press, 2014. He has presented papers in London, Oxford, Cardiff, Southampton, Meiningen, Leipzig, Weimar, New York, Boston, New Haven, Nashville and elsewhere. In June 2016, he and Valerie Goertzen of Loyola University New Orleans co-hosted the International Conference Joseph Joachim at 185 at the Goethe Institut Boston.
Eshbach is an associate professor of music at the University of New Hampshire.
Eshbach, R. W. (n.d.). 'For all are born to the ideal' Joseph Joachim and Bettina von Arnim. Music and Letters.


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Renee Zellweger Is Now Completely Unrecognizable
Renée Zellweger
Antoinette Bueno
American actress and producer
Yes, this is really Renee Zellweger.
It's safe to say Renee Zellweger's looking a little different these days.
The 45-year-old actress made an appearance at ELLE's 21st Annual Women In Hollywood Celebration in Beverly Hills, Calif. Monday night, and her nearly unrecognizable appearance is shocking to say the least.
No, your eyes are not deceiving you -- this really is what the Bridget Jones' Diary star currently looks like.
PHOTOS: Most Shocking Celeb Transformations
Though many speculate that Renee's new look is the result of plastic surgery -- pointing to her completely wrinkle-free face -- she has never addressed the reports.
She has, however, commented on the criticism that she's too thin.
"When you read reports that you are starving yourself or that you are anorexic it's very unfair and disappointing," she told the U.K.'s Daily Express last November. "It's not very pleasant to read reports which say you've gone too far or this or that. I have a lifestyle that involves keeping my sanity by going to the gym."
But clearly, her fans weren't too happy with her new look on social media.
The "new" "Renée Zellweger" is BLOWING MY MIND I DON'T UNDERSTAND WHAT IS THIS VOODOO I AM TERRIFIED. pic.twitter.com/e0jB0Rosd3
— HannahJane Parkinson (@ladyhaja) October 21, 2014
Renee Zellweger no longer looks like Renee Zellweger and it's freaking me out. http://t.co/74fvsPaZp1 pic.twitter.com/pMZCRSSqfe
— BarstoolTrent (@BarstoolTrent) October 21, 2014
I'm a Renee Zellweger new face truther. That cannot be her. http://t.co/xmpvl5mctx
— Elise Foley (@elisefoley) October 21, 2014
Renee has not been seen on the big-screen since 2010's My Own Love Song, but is set to make her return in the thriller The Whole Truth, out in 2015. The film, which also stars Keanu Reeves, is about a defense attorney working to get his teenage client acquitted of murdering his wealthy father.
There has also been much talk about a third Bridget Jones' Diary film, though Hugh Grant recently confirmed that he won't be involved.
"I decided not to do it," the 54-year-old actor told Free Radio in the West Midlands, "but I think they're going to go ahead and do it without Daniel. The book's excellent, by the way, but the script is completely different -- well, the script as I last saw it a few years ago."
NEWS: Renee Zellweger Reacts to Rumors About Her Appearance
Check out the video below to reminisce about a very different looking Renee when she appeared as an extra in 1993's Dazed and Confused below.
Zoe Kravitz Looks Just Like A Young Lisa Bonet In Her Bikini
The Hottest, Weirdest and Funniest Celeb Halloween Costumes
The Full Duggar Family Tree in Pics
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Las analfabetas  es una película chilena de 2013, dirigida por Moisés Sepúlveda y con un guion escrito por el mismo Sepúlveda y Pablo Paredes Muñoz, autor también de la aclamada obra teatral en que se basa.  Fue seleccionada para ser presentada como cierre en la Semana de la Crítica del Festival Internacional de Cine de Venecia, 2013 y en el SANFIC del mismo año, donde obtuvo los premios de Mejor Película Chilena y el Premio del Público

Argumento
Ximena es una mujer adulta que vive sola en un sencillo departamento, ajena al mundo que la rodea por ser analfabeta, algo que la avergüenza. Sin mucha convicción acepta la ayuda de Jackeline, una joven egresada de Educación, que le brindará asistencia para aprender a leer y así poder enterarse del contenido de una carta que le dejó su padre. La relación entre las dos mujeres devendrá en un aprendizaje mutuo que irá más allá del tema de la lectura, y arrojará luces que justificarán el plural  "analfabetas" con que se tituló la película.

Reparto
 Paulina García
 Valentina Muhr

Premios y nominaciones
Santiago Festival Internacional de Cine 2013
 Mejor Película chilena: Las analfabetas, Ganadora
 Premio del Público: Las analfabetas, Ganadora

Festival Internacional de Cine de Mar del Plata 2013
 Mejor Película: Las analfabetas, Nominada
 Premio Feisal: Las analfabetas, Ganadora

Festival de Cine Iberoamericano de Huelva 2013
 Mejor Opera Prima: Las analfabetas, Ganadora

Festival Internacional de Cine de Chicago 2013
 Mejor Nuevo Director: Moisés Sepúlveda, Nominado

Festival de Cine de Gramado 2014
 Mejor Película: Las analfabetas, Nominada
 Mejor Director: Moisés Sepúlveda, Ganador
 Mejor Actriz: Paulina García y Valentina Muhr, Ganadoras
 Mejor Cinematografía: Arnaldo Rodríguez, Ganador

Premio Iberoamericano de Cine Fénix 2014
 Mejor Actriz: Paulina García, Nominada

Premios Platino 2015
 Mejor Actriz: Paulina García, Nominada

Las analfabetas ha sido invitada a participar en más de 30 Festivales de Cine de varios países, incluido Chile, donde ha logrado una recepción exitosa sumado al gran interés que siempre despierta la opera prima de un joven director.

Referencias

Enlaces externos

 Las analfabetas en FilmAffinity
 Las analfabetas en CineChile

redpajama_set_name: RedPajamaWikipedia


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What Is a Nephrologist?
More in Healthcare Professionals
Healthcare Compensation
Healthcare Trends
A Specialist Trained in Diseases of the Kidneys
Andrea Clement Santiago
Andrea Clement Santiago is a medical staffing expert and communications executive. She's a writer with a background in healthcare recruiting.
Medically reviewed by Richard N. Fogoros, MD on May 28, 2019
Richard N. Fogoros, MD, is a retired professor of medicine and board-certified internal medicine physician and cardiologist. He is Verywell's Senior Medical Advisor.
Richard N. Fogoros, MD
Updated on July 17, 2019
Procedural Expertise
Appointment Tips
A nephrologist is a doctor who specializes in kidney health and kidney disease. In medical practice, the term renal is used to describe anything involving, affecting, or located near the kidneys, so nephrologists are often referred to as renal specialists.
Nephrology is a subspecialty of internal medicine. Therefore, a nephrologist needs to complete the same training as an internist before pursuing an additional fellowship in nephrology. According to the American Society of Nephrologists (ASN), there are just over 10,000 nephrologists actively practicing in the United States.
The term nephrology is derived from the Greek nephros meaning "kidneys" and the suffix -ology meaning "the study of."
Nephrology encompasses a wide range of medical disciplines, including:
The study of normal kidney function
The causes and diagnoses of kidney diseases
The treatment of acute or chronic kidney diseases
The preservation of kidney function
Nephrology also involves the study of systemic conditions that affect the kidneys (such as diabetes and autoimmune diseases) and systemic diseases that occur as a result of kidney disease (such as hypertension or hypothyroidism).
While it's possible that you may see a nephrologist in a hospital setting, due to a limited number of such positions, you're more likely to see a nephrologist in a private practice or dialysis facility.
Nephrologists are typically called in when there are signs of kidney injury or disease. For instance, people are often referred to a nephrologist after a urinalysis picks up an abnormality, such as hematuria (blood in urine), proteinuria (excess protein in urine), or an imbalance of electrolytes or urinary pH. In other cases, overt symptoms of kidney disease may be seen.
Broadly speaking, kidney diseases can be classified as either acute or chronic:
Acute kidney injury (AKI) is the abrupt loss of kidney function that develops within seven days. The symptoms can vary by the underlying cause but may include the rapid onset of fatigue, loss of appetite, headache, nausea, vomiting, increased thirst, abnormal heart rhythms, pain in the flank, and rash. This illness is of short duration, rapidly progressive, and in need of urgent care.
Chronic kidney disease (CKD) is characterized by the gradual loss of kidney function over a period of months or years. Early on, there may be no symptoms. Later, fatigue, edema (leg swelling), muscle cramps, vomiting, loss of appetite, persistent itching, chest pains, shortness of breath, or confusion may develop.
While there may be an overlap of symptoms, the speed and nature of these symptoms can provide a nephrologist the clues needed to initiate diagnosis and treatment.
Understanding the Causes of Kidney Pain
Because the kidneys perform so many critical functions, nephrologists are generally focused on primary kidney disorders—that is, those originating in these important organs.
Although the prevention and management of early kidney disease are within the scope of a nephrology practice, nephrologists are usually called upon to assist with more complex or advanced renal disorders.
These may include:
Amyloidosis, the buildup of abnormal proteins, called amyloids, in various organs of the body (including the kidneys)
Congenital kidney malformations
Diabetic nephropathy, the number one cause of kidney disease
Glomerulonephritis, a disease that affects tiny units in the kidneys, called glomeruli, where blood is cleaned
Lupus nephritis, inflammation of the kidneys caused by the autoimmune disease lupus
Nephrotic syndrome, a disorder that causes your body to excrete too much protein in your urine
Polycystic kidney disease, a genetic disorder in which clusters of cysts develop within the kidneys
Pyelonephritis, a type of urinary tract infection where one or both kidneys become infected
Renal failure, in which the kidneys fail to adequately filter waste products from the blood
Renal obstruction, caused by kidney stones, tumors, an enlarged prostate, and other conditions
Renal stenosis, the narrowing of arteries to the kidney typically linked chronic hypertension
When Should You See a Kidney Doctor?
A nephrologist is qualified to provide all facets of treatment of kidney disease, either primary or secondary. This may involve medications (including ACE inhibitors, statins, diuretics, or calcium and vitamin D supplements) or the management of lifestyle factors (including diet, smoking, and weight loss).
Nephrologists can also perform, oversee, or assist in other procedures to either manage or treat kidney disorders. These include:
Percutaneous needle biopsy (the insertion of a needle through the abdomen to obtain kidney specimens)
Kidney ultrasonography: Using ultrasound to help monitor a disease or guide certain medical procedures)
Bone biopsy to monitor and manage bone disorders associated with kidney cancer or CKD
Kidney dialysis, including hemodialysis, peritoneal dialysis, and continuous renal replacement therapy
Kidney transplants
Some nephrologists will opt to specialize in a narrower field of practice. These typically involve additional training and research fellowships. Among some of the most common nephrology subspecialties are:
Critical care nephrology
Kidney dialysis (including arteriovenous fistula surgery)
Interventional nephrology (involving ultrasound-guided procedures)
Onconephrology (involving cancer-related kidney diseases)
Nephrologists may also provide care to people without kidney problems and work in different fields of medicine, including internal medicine, transplant medicine, intensive care medicine, clinical pharmacology, or perioperative medicine.
A physician can specialize in nephrology through two different educational paths. In both cases, they would first complete medical school as a doctor of medicine (MD) or doctor of osteopathic medicine (DO) and then spend at least five years in specialty training.
To specialize in adult nephrology, the doctor would complete a three-year residency in internal medicine and then a fellowship in nephrology of at least two years.
To specialize in pediatric nephrology, a doctor would complete either a three-year pediatric residency or a four-year combined internal medicine/pediatrics residency, followed by a three-year fellowship in pediatric nephrology.
After the completion of training, the doctor is eligible to take the board exam and be certified in nephrology by either the American Board of Internal Medicine (ABIM) or the American Osteopathic Board of Internal Medicine (AOBIM). Some nephrologists continue with additional fellowships in nephrology subspecialties.
When searching for a nephrologist, do not hesitate to ask for several referrals, either from your general practitioner or health insurer. Before making your first appointment, be sure that the office accepts your insurance coverage. If you are not insured, ask if they offer a payment plan.
Although there are only two certifying bodies for nephrologists in the United States, only the ABIM allows you to check their certification online through their verification website. The credentials of non-ABIM nephrologists can often be confirmed through the non-profit Certification Matters website offered by the American Board of Medical Specialties (ABMS).
Alternately, don't be afraid to ask the doctor to provide you with their credentials. You can then conduct your own search through the state licensing board.
When meeting with a nephrologist for the first time, ask a few questions to better understand your condition and what may be involved. For example, you might ask:
Why was I referred to see you?
Why are my kidneys not functioning as they're supposed to?
What is the current state of my kidneys?
How rapidly is my kidney function declining?
What can I do to slow or reverse this?
What are my options for treatment?
What will happen if I choose not to be treated?
Who and when should I call if I have any problems?
The doctor's responses will provide insights as to whether you are being fully listened to and provided the information needed to make an informed choice.
If you are not provided the responses you need in clear and understandable language, do not hesitate to seek a second opinion.
Nephrologists tend to work in the same areas where they are trained, rather than seeking employment where they are most needed. As such, you may need to travel to see a nephrologist if you live in certain areas.
Get tips on how to better manage your health practice.
Salsberg E, Quigley L, Mehfoud N, Masselink L, Collins A. The US Adult Nephrology Workforce 2016: Developments and Trends. Washington, DC: American Society of Nephrologists; 2016.
Quigley L, Salsberg E, Collins A. Report on the Survey of 2018 Nephrology Fellows. Washington, DC: American Society of Nephrologists, 2018.
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Some of Australia's most celebrated authors will visit India as part of Australia Fest to inspire new audiences for Australian books and culture.
The authors will participate at various events across India including the Jaipur Literature Festival (24-28 January), Apeejay Kolkata Literary Festival (18-20 January), Kolkata Literary Meet (22 - 27 January), and Kala Ghoda Arts Festival (2-10 February).
"Australia and India have a shared passion for great writing, and I am delighted that we are able to share the diversity of Australian stories with Indian audiences through some of our most prolific writers," said Her Excellency Ms Harinder Sidhu, Australia's High Commissioner to India.
The diverse line-up includes: author of international bestseller The Book Thief Markus Zusak; Lifetime Ambassador of the Indigenous Literacy Foundation Anita Heiss; co-authors of Waste of a Nation: Garbage and Growth in India Robin Jeffery and Assa Doron; a leading expert in the field of artificial intelligence Toby Walsh; a former diplomat and foreign correspondent with three books on India to his credit John Zubrzycki; and an academic engaged in exploring the many ways that humans interact with nature Darryl Jones.
The tour offers a great opportunity for the Australian authors to introduce their award-winning titles to the Indian audiences at various festivals, participate at public-speaking events and interact with Indian writers and scholars.
Complementing the authors' tour, a delegation of leading Australian publishers and festival directors will take part in Jaipur Bookmark and Hyderabad Literary Festival as part of the Australia Council for the Arts' Literature Exploratory Program.
Anita Heiss is proud member of the Wiradjuri nation of central New South Wales. Dr. Heiss is one of Australia's most prolific and well-known authors publishing across genres such as non-fiction, historical fiction, commercial fiction and children's novels. Her latest book as editor is Growing Up Aboriginal in Australia.
Markus Zusak is the author of five books, including the international bestseller, The Book Thief, which spent more than a decade on the New York Times bestseller list and has been translated into more than 40 languages – establishing Zusak as one of the most successful authors to come out of Australia. To date, Zusak has held the number one position on Amazon.com, Amazon.co.uk, the New York Times bestseller list, as well as in countries across South America, Europe and Asia.
Robin Jeffrey is a visiting research professor at the Institute of South Asian Studies, Singapore. His recent book, written with Assa Doron, is Waste of a Nation: Garbage and Growth in India. He is also the co-author with Doron of Cell Phone Nation and the author of India's Newspaper Revolution.
John Zubrzycki's first experience of India was a dorm bed at the Salvation Army Guest House in Calcutta 40 years ago. Since then, he's chalked up a degree in Indian history, travelled to every corner of the subcontinent, worked as a diplomat and foreign correspondent in New Delhi and written three eclectic books on India. His latest, Jadoowallahs, Juggler and Jinns, traces the evolution of Indian magic.
Toby Walsh was named a 'rock star' of Australia's digital revolution. He is a Professor of Artificial Intelligence and fellow of the Australian Academy of Science. He regularly appears in the media talking about AI and robotics. His latest book, 2062: The World that AI Made, was published in August 2017.
Darryl Jones is an academic at Griffith University in Australia who has been engaged in exploring the many ways that humans interact with nature, both positively and negatively. Most recently, this has involved a global study of wild bird feeding with remarkable findings.


"Fremennik not-Santa is collecting for a good cause."
During the 2014 Christmas event he can be found near the Lumbridge, Edgeville, Burthorpe or Prifddinas lodestones.
During the 2014 Christmas event for bond you give to Thorvar (who will donate it to the charity Oxfam) you will receive a present. Each bond you donate you will receive an oxfam present and a tradeable oxfam present.