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Keith Richards interview - Wall Street Journal, November 11
Posted by: bye bye johnny ()
Date: November 12, 2020 15:30
Germano Studios, 2015/J. Rose
Keith Richards on Covid-19, the Next Rolling Stones Album and His Solo Career
The 76-year-old guitarist expects to return to the road, but older bands like the Stones could 'throw in the towel' if concerts don't resume in coming years
By Neil Shah
[www.wsj.com]
Re: Keith Richards interview - Wall Street Journal, November 11
Posted by: maumau ()
on the new album he sounds frank, thanks for sharing
Posted by: slewan ()
best line (and so true):
Q: Do the Stones plan to tell fans when it's going to be their last tour?
A: We tell them every time that it's the last tour! [laughs]
Posted by: dcba ()
"I'd love to get onstage now, you know? I'd go for nothing"
Good news Keith... but don't tell Mick!
Posted by: Irix ()
There's a paywall - can someone paste the interview-text here?
Posted by: Rip This ()
really....as if I'd give Murdoch a @#$%& dime....not happening.
Posted by: Hairball ()
Based on intuition and the posts in this thread, the interview seems to be a near duplicate of the other recent interviews:
- New album half way done
- Been writing songs. and gardening
- I wrote Satisfaction in my sleep
- Winos were a great band
- Would love to tour
- The pandemic is crap
- We released Ghost Town
There might be a couple of variables in the questions/answers, but there seems to be a pattern.
Keith must be getting bored doing this recent press, but then again easy money for the re-release of a 30 year old album.
Keep on rolling.......
Posted by: MadMax ()
Just push the X mate and then you can read it!
WSJ writer Neil Shah posted a couple of "bonus tracks":
Posted by: Cristiano Radtke ()
I've found this version of the WSJ interview which I'm not sure if it's an accurate copy:
How does an inveterate rock 'n' roller like Keith Richards deal with a pandemic thwarting his touring plans? He dusts off and re-releases a live album.
This Friday, the Rolling Stone puts out a deluxe version of "Live at the Hollywood Palladium," which documents a 1988 concert by his solo band, the X-Pensive Winos.
Released in 1991, "Live at the Hollywood Palladium" captures the ragged, rollicking sound of the Winos, a band that provided Mr. Richards with a creative outlet during a stand-off with Mick Jagger in the 1980s and has since amassed a cult following. Joining Mr. Richards in the Winos are guitarist Waddy Wachtel, keyboardist Ivan Neville and drummer Steve Jordan. Mr. Jordan is something of a foil for Mr. Richards: He co-writes and co-produces Mr. Richards' solo music, including 1988's beloved album "Talk Is Cheap." The expanded live album includes three previously unreleased tracks, including "You Don't Move M
Mr. Richards, 76, spoke with the Journal about quarantining, the most recent on the Stones' album and touring plans and his recollections of his first solo tour in 1988. Edited from an interview:
Because you're Keith Richards, I've to ask: Are you taking particular precautions to remain protected?
I'm at dwelling in Connecticut, doing what everyone else is doing—attempting to keep away from this factor. I've acquired household with me, so it's type of a bubble. I wash my palms; if I am going out, I put on a masks. Laying low—is the best way you'd put it. If there's anything you are able to do, let me know!
What about staying in form? Do you might have a regime for exercising or working towards guitar?
I hate regimes. Often, my train is working with the Stones. However I've acquired a treadmill downstairs, which I reluctantly plod round on for half an hour. Through the summer time, we take walks. However I do have to consider this winter—till I get down on the islands. My escape route goes south for the winter.
In relation to performing, I've little doubt—I really feel a bit rusty, having not performed it for over a 12 months now. However I don't really feel bodily much less succesful than I did two years in the past. I actually have much more enthusiasm. I'd like to get onstage now, I'd go for nothing.
Realistically, when do you assume the Stones will get again on the street?
We're all hoping that within the coming 12 months there's some optimistic reduction. In the intervening time, every little thing's simply pure hypothesis. Given the chance, we'll be again.
Any extra songs you'll be able to inform me about?
I can't provide you with any previews as a result of the songs are in varied states of composition—or decomposition, relying on the case! [laughs]
Let's speak about your 1988 tour with the Winos. What do you bear in mind?
Effectively, I'd by no means been a front-man earlier than. I imply, I do my one or two songs reside, inside the context of the Stones. Nevertheless it was the opposite guys within the Winos, and "Discuss Is Low-cost," that gave me the sensation that, sure, I'd prefer to tour. At first, we have been simply going to make a report. By the point we have been ending, we had the sensation we have been an precise band. This band was made to play reside. I've loved myself a lot. Though I have to say, I did study an terrible lot about Mick's job—being the front-man. That's a continuous process.
I'm guessing it was a change to sing for an entire present as an alternative of only a couple songs an evening.
We took fairly some time rehearsing, simply to get road-worthy, in that respect. Throughout rehearsals, I acquired over the primary hump of my voice going away and disappearing—although I did lose my voice later at one present in Las Vegas [in 1993]. It's wonderful, the human voice. It's like a muscle, it will get stronger with use.
A spotlight of "Dwell on the Hollywood Palladium" is the two-guitar interaction between you and Waddy Wachtel. Traditionally, why haven't extra rock bands had two guitarists, other than the extra prices?
One of many solutions can be an excessive amount of ego. Guitar gamers are well-known for it. Quite a lot of them, particularly rock guitar gamers, assume very selfishly. One guitar by itself, I can hearken to for, like, I don't know, relying on the virtuosity, 5 or 6 minutes. However the complexity of including yet one more guitar has at all times fascinated me. Even, at occasions, three. However that must be a special day [laughs]. Little Walter and his Jukes [the blues musicians]—they confirmed me the chances of two guitars.
Your final solo album, 2015's "Crosseyed Coronary heart," was warmly acquired. Do you need to make one other?
Yeah, I do. In the intervening time, after all, I additionally would like to make a Rolling Stones album [laughs]. However yeah, I look again on the Winos fondly, as an incredible expertise, as a widening expertise. As a result of I had solely ever labored with the Rolling Stones, ? The Winos are an actual feather in my cap. If it have been my resume, I'd put it on the high of the record.
Cristiano Radtke
There's no 'X' in my Browser .... only 'Subscribe' or 'Sign In'. But the version from the [Twitter.com] link worked for a short moment.
Edited 2 time(s). Last edit at 2020-11-12 21:05 by Irix.
Posted by: DandelionPowderman ()
"Crosseyed Coronary heart"...
[Twitter.com] - version of the interview with more Stones-parts:
By Neil Shah · Nov. 11, 2020 10:16 am ET
Released in 1991, "Live at the Hollywood Palladium" captures the ragged, rollicking sound of the Winos, a band that provided Mr. Richards with a creative outlet during a stand-off with Mick Jagger in the 1980s and has since amassed a cult following. Joining Mr. Richards in the Winos are guitarist Waddy Wachtel, keyboardist Ivan Neville and drummer Steve Jordan. Mr. Jordan is something of a foil for Mr. Richards: He co-writes and co-produces Mr. Richards' solo music, including 1988's beloved album "Talk Is Cheap." The expanded live album includes three previously unreleased tracks, including "You Don't Move Me."
Mr. Richards, 76, spoke with the Journal about quarantining, the latest on the Stones' album and touring plans and his memories of his first solo tour in 1988. Edited from an interview:
Since you're Keith Richards, I have to ask: Are you taking special precautions to stay safe?
I'm at home in Connecticut, doing what everybody else is doing—trying to avoid this thing. I've got family with me, so it's kind of a bubble. I wash my hands; if I go out, I wear a mask. Laying low—is the way you'd put it. If there's anything else you can do, let me know!
What about staying in shape? Do you have a regime for exercising or practicing guitar?
I hate regimes. Usually, my exercise is working with the Stones. But I've got a treadmill downstairs, which I reluctantly plod around on for half an hour. During the summer, we take walks. But I do have to think about this winter—until I get down on the islands. My escape route is going south for the winter.
When it comes to performing, I've no doubt—I feel a bit rusty, having not done it for over a year now. But I don't feel physically less capable than I did two years ago. I certainly have a lot more enthusiasm. I'd love to get onstage now, you know? I'd go for nothing.
Realistically, when do you think the Stones will get back on the road?
We're all hoping that in the coming year there's some positive relief. At the moment, everything's just pure speculation. Given the opportunity, we'll be back.
The halting of big concerts raises a question: Do you think an older generation of rock acts could just stop touring?
Yeah, it's a viable question. It depends on how long this drags on. If there's relief next year or even 2022, I'd say probably most of those people, including us, would pick up where we left off. But if you can't pull crowds together soon, in another 18 months or two years, it's quite possible everybody would throw in the towel.
Do the Stones plan to tell fans when it's going to be their last tour?
We tell them every time that it's the last tour! [laughs]
The Stones have been making a new album for several years. What's the status?
That's on hold as well. Mick and I fling a few ideas across the Atlantic, occasionally. Apart from that, I did get one session in with [producer] Don Was to do some overdubs about three weeks ago. It was a daring adventure, going into the city. But we're stuck halfway through. We've got maybe five, six tracks. One of which was "Living in a Ghost Town" [which was released in April]. We put that out immediately because it was so appropriate—because of the images coming off of the TV in March. I was listening to it, saying, this is the soundtrack to this thing—we've got to put it out now. Otherwise, we would've kept it for later.
Any more songs you can tell me about?
I can't give you any previews because the songs are in various states of composition—or decomposition, depending on the case! [laughs]
Let's talk about your 1988 tour with the Winos. What do you remember?
Well, I'd never been a front-man before. I mean, I do my one or two songs live, within the context of the Stones. But it was the other guys in the Winos, and "Talk Is Cheap," that gave me the feeling that, yes, I'd like to tour. At first, we were just going to make a record. By the time we were finishing, we had the feeling we were an actual band. This band was made to play live. I've enjoyed myself so much. Although I must say, I did learn an awful lot about Mick's job—being the front-man. That's a non-stop task.
I'm guessing it was a change to sing for a whole show instead of just a couple songs a night.
We took quite a while rehearsing, just to get road-worthy, in that respect. During rehearsals, I got over the main hump of my voice going away and disappearing—though I did lose my voice later at one show in Las Vegas [in 1993]. It's amazing, the human voice. It's like a muscle, it gets stronger with use.
A highlight of "Live at the Hollywood Palladium" is the two-guitar interplay between you and Waddy Wachtel. Historically, why haven't more rock bands had two guitarists, apart from the additional costs?
One of the answers would be too much ego. Guitar players are famous for it. A lot of them, especially rock guitar players, think very selfishly. One guitar by itself, I can listen to for, like, I don't know, depending on the virtuosity, five or six minutes. But the complexity of adding one more guitar has always fascinated me. Even, at times, three. But that has to be a special occasion [laughs]. Little Walter and his Jukes [the blues musicians]—they showed me the possibilities of two guitars.
Your last solo album, 2015's "Crosseyed Heart," was warmly received. Do you want to make another?
Yeah, I do. At the moment, of course, I also would love to make a Rolling Stones album [laughs]. But yeah, I look back at the Winos fondly, as a great experience, as a widening experience. Because I had only ever worked with the Rolling Stones, you know? The Winos are a real feather in my cap. If it were my resume, I'd put it at the top of the list.
Posted by: IanBillen ()
There are five or six songs in the works (what happened to "20"?) .. Hmmmmm well .... that's about a song a year they start to get down to .. not too shabby eh? .. .. ...
IanBillen
Hmmmmm well .... that's about a song a year they start to get down to ..
So, new 10-Track Album out then in 2025 when they threw the Tour-towel .... (one of the 6 current Tracks was already released).
Yep ... Five or six songs ... actually might be four .. considering LIAGT was already released. Four or five tunes every five years is prolific. Im impressed. That would mean one album every twenty years as you indicated.
This while thing is almost ..well wait.. it is and has been for a while now .. a damn joke. These guys are ridiculous.
Hairball? Where are you here on this in venting with Irix and I?
Posted by: Chris Fountain ()
What is an X-mate?
You're not very far from the truth.
From another interview you missed the "B2B is a seriously under-rated album" claim, with which I would agree.
Because I must have hit a wall trying to come up with something else to say, but unlike the Stones, I'll bounce back within a couple of hours and won't let it keep me down and out indefinitely lol...........
*PS - See new album thread - I already vented their earlier today, and yesterday I chimed in on the Keith Richards interview - USA Today thread.
Not a day goes by when I don't vent about the supposed/imaginary new album.
Edited 1 time(s). Last edit at 2020-11-12 23:45 by Hairball.
Posted by: black n blue ()
The fellows aren't motivated at all seems like to me. See McCartney different cat or Dylan.
Posted by: cowboytoast ()
they aren't doing anything...it's really disgusting to be honest - but if they don't have the inspiration or the motivation then maybe it's for the best - there is probably a lot of anxiety on Mick's part - cuz it'll be the last album and he knows it and they are going up against their legacy - even if they put out an album tomorrow there would certainly not be another 15 years between albums again-
Chris Fountain
He meant that the mate should click/tap on the 'X'-(close)-button of the WSJ self-advertising pop-up window.
There's no 'X'-(close)-button in the original article-link of Post #1, but it appears in the article-link given via Twitter (depends maybe on the Browser).
Posted by: emotionalbarbecue ()
It may be wrong to expect at their age and present social context "an album".
Furthermore...does "album" at the present have the traditional meaning? or does it cause nowadays the traditional expectation?
Marginal note: My daughter and her friends do not know what an album is. All they understand/know is clicking in spotify, youtube and so on.
Edited 1 time(s). Last edit at 2020-11-13 12:41 by emotionalbarbecue.
emotionalbarbecue
Furthermore...does "album" at the present have the traditional meaning?
I think it would still be possible to make an Album in the traditional meaning - simply tell a story across all songs, like Pink Floyd in 'The Wall' (or a theme, like Kraftwerk's Album 'Tour de France').
The fan base of the Vinyl is growing again - hard to imagine that they constantly jump from song to song like via Streaming ....
Posted by: pftw04 ()
As per the interview of Wall street journal, where Keith has claimed that he got rusty again for not playing/practice for a year. Well it does not matter as the band has retired. And Keith himself hinted that age is not at there side.
Re: Keith Richards
[iorr.org]
Posted by: TheflyingDutchman ()
Isn't it ironic that the greatest R&R band in the world has been censored by an invisible opponent? That's the last scenario anyone could have come up with.
Posted by: noughties ()
What an original thread title!
Right now there's six separate threads for Keith on page one of IORR - this must be a record!
Will there be seven, or maybe eight?
Go Keith!
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Home Movies Star Wars: The Force Awakens The Force Awakens Soundtrack Debuts at #5 on the Billboard top 200!
The Force Awakens Soundtrack Debuts at #5 on the Billboard top 200!
Ashley Wilbanks
Star Wars: The Force Awakens Soundtrack
Not only has Star Wars: The Force Awakens taken the box office by storm, but John Williams' brilliant soundtrack for the movie is taking the Billboards by storm as well! You can grab your copy of the soundtrack right now on Amazon for a mere $12.29!
You can find the press release below:
Star Wars: The Force Awakens Original Motion Picture Soundtrack From Oscar®-Winning Composer John Williams Debuts At No. 5 On The Billboard 200 Chart
BURBANK, Calif., Dec. 29, 2015 /PRNewswire/ — The original motion picture soundtrack for the record-breaking Star Wars: The Force Awakens, featuring new score conducted and composed by five-time Academy Award®-winning composer John Williams, has entered the Billboard 200 chart at No. 5, scanning over 100,000 equivalent album units in its first week of release, according to Nielsen SoundScan. The last and only all-score soundtrack to debut in the Top 5 was Star Wars Episode I: The Phantom Menace in 1999.
The album is No. 1 on Billboard's Soundtrack and Overall Classical Charts; at iTunes, peaked at No. 1 on the Soundtrack chart and No. 3 on the Overall Album chart; and at Amazon, the album is No. 1 on the Soundtrack chart and No. 2 on the Overall Digital Album chart. Additionally, the album has over 10.3M streams on Spotify.
From Lucasfilm and visionary director J.J. Abrams, Star Wars: The Force Awakens has broken numerous box office records, most recently becoming the fastest film to reach $1 billion globally, a feat it accomplished in 12 days with over $540 million domestically and$550 million internationally. It posted the biggest debut in industry history with $248 milliondomestically and $529 million globally in its first weekend, as well as the biggest second weekend of all time domestically with $149.2 million.
Oscar®-winning composer John Williams' ubiquitous Star Wars "Main Title" theme has become part of popular culture since it was first heard accompanying Star Wars: A New Hope in 1977. It is no surprise that Williams' orchestral compositions for Star Wars are among the most beloved and recognizable themes in cinematic history, from the classic "Main Title" theme introduced in Star Wars: A New Hope to the ominous "Imperial March" from Star Wars: The Empire Strikes Back to the stirring "Duel of the Fates" from the prequel trilogy.
After creating the scores for all six of the previous Star Wars films, Williams returns to compose and conduct his signature sweeping music for The Force Awakens.
Williams, whose career spans over six decades, has won five Academy Awards® and he has scored some of the most popular and critically acclaimed films of all time, includingJaws, the Indiana Jones franchise, the first three Harry Potter films, E.T. The Extra Terrestrial, Lincoln, Schindler's List, and countless others.
The soundtrack for Star Wars: The Force Awakens is now available wherever music is sold (http://smarturl.it/swtfa).
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For more information on Star Wars: The Force Awakens, please visithttp://www.theforceawakens.com. For more information on Walt Disney Records'releases, like us on Facebook.com/disneymusic or follow us atTwitter.com/disneymusic. For more information on Disney Music Emporium, please visitDisneyMusicEmporium.com, become a fan at Facebook.com/disneymusicemporium or follow us at Twitter.com/DisneyMusicEmp.
SOURCE Walt Disney Records
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Sarah Harding, an Irish/English pop star from the girls group Girls Aloud, recently admitted that she has an addiction to sleeping pills. Zopiclone is a non-benzodiazipine given out in the UK for insomnia. Harding was mixing her sleeping pills with alcohol which is a lethal combination.
In the states, Ambien is the most common sleeping pill prescribed by our medical profession. Ambien has side effects such as sleepwalking, hallucinations and possible amnesia. All sleep medication should be taken for a short period of time, approximately 6 weeks. When Ambien is combined with alcohol, the effects can be deadly.
Most addicts struggle with sleep even after drug rehab. Their primary doctors prescribe sleeping pills thinking that it will help, yet when it comes to addiction the opposite is true. Artificial sleep inducers will only prolong your body's' adjustment period when trying to regain a balanced sleep cycle. It may be more advantageous to attempt relaxation techniques, exercise and holistic remedies prior to seeking artificial treatments.


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Hadrian's Wall: 2-Hour Guided Tour
Travel back 2000 years to a time when Hadrian's Wall was a frontier, a place where two cultures collided, on this award-winning tour. Find out more about Roman history with a local guide, and delight in scenic views of the Northumberland National Park.
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Walk in the footsteps of the Roman army with Hadrian's Wall as a backdrop
Soak up the amazing atmosphere of the stunning Northumbrian landscape
Gain a deeper understanding of Hadrian's Wall, the men who garrisoned it, and the local Celtic tribes
Feel Roman history come to life as you discover just what Britain was like under the Caesars on this 2-hour tour of Hadrian's Wall. Explore this breathtaking UNESCO World Heritage Site with a local guide dressed in an authentic costume of the era, and discover hidden archaeological gems. Hear your guide weave a narrative from both sides of the wall — the tales of the natives and the stories told by the occupying forces — and walk along the iconic central section of Hadrian's Wall. See a milecastle (a rectangular fortification) and one of the best sections of the Vallum defensive ditch. Throughout your tour, admire the magnificent backdrop of the Northumberland National Park, and enjoy some of the best views across the rugged moorland vistas.
Guided tour in English
Transport to and from the start location
Masks are optional for this activity
Meet your guide at the car park at Cawfields Quarry, North Rd, Haltwhistle, Northumberland NE49 9NN, UK. Please arrive 10-15 minutes before the tour is due to start.
Your guide will be dressed in authentic clothing for this tour. The guide, however, reserves the right to wear modern clothing if the weather causes concerns for health and safety
The tour takes place outdoors with uneven paths to walk on. Walking boots and warm, waterproof clothing are recommended
Haltwhistle is the closest train station to the meeting point at Cawfields on Hadrian's Wall. Regular trains arrive at Haltwhistle from Newcastle and Carlisle. The AD 122 bus runs from Haltwhistle train station to the Milecastle Inn; from here, it is a short walk to Cawfields. An internet search will provide up to date train and bus times
Toilet facilities are located at the Cawfields Car Park
You will need £1 per hour for the car park
Please arrive 10-15 minutes before the tour start time
My dad and I were fortunate to be the only people on this tour and our guide was friendly, knowledgeable, helpful and courteous, making sure that my dad with his mobility limitations could safely enjoy the walk. I would recommend this tour to anyone who would like to see one of the most iconic sections of Hadrian's Wall whilst learning about Roman history from a great guide. Thank you for making our holiday extra special.
Emma – United Kingdom Verified booking
Very interesting tour, guide was very knowledgeable. We will be booking a longer tour next time
Paul – United Kingdom Verified booking
AncientBritain


Hey friends, family, and fans!
Today, we began our day at Head Start, which is the largest Head Start in the state of Montana. It was a fun experience for us to get to spend time with children 3-5 years old. We had the chance to assist with tasks in the classroom, play with children on the playground, and learn more about the history behind the facility. We are starting to build relationships with the children and are excited to spend the rest of the week with the kids.
We also went to Montana Rescue Mission today. We did not serve food as we were expecting too, but did things that helped to support the Mission to raise money to provide for the soup kitchen. We learned a lot about ourselves and our approach to service today at MRM.
Tomorrow we will be back with the kids and are super stoked for what's to come with them!


Firstly, thanks to Alan & Kath Witherby for hosting our Easter event 'Daffodils' at Rydal Mount, Wissett on Easter Sunday. Once again, it was an enjoyable and successful afternoon and altogether a grand total of £495.60 was raised. Despite most of the daffodils being over, visitors still enjoyed wandering around the beautiful gardens at Rydal Mount, and welcomed homemade refreshments in the conservatory, and there were no snow showers this year to hamper proceedings! A big thank you to everyone involved with organising, baking, donating prizes, helping on the day and of course to everyone that supported us. Thank you to the Co-operative food store in Halesworth for donating an Easter egg, which was won by Norman Hatcher. The lucky winner of the Easter Hamper was Dudley Clarke.
We have received a donation from Mrs J Lea, and a donation in memory of Violet Hammond, grateful thanks for these.
The countdown has begun to our Annual Summer Fete, which is on Saturday 31st May in the hospital grounds. The fun starts at 1.00pm and runs through until 4.30pm. We are pleased to welcome Charlie Haylock this year, who is going to start proceedings at 1.00pm. Charlie is one of Suffolk's leading entertainers and has a regular spot on Radio Suffolk with Lesley Dolphin, currently exploring the lost words of Suffolk. We have entertainment throughout the afternoon including the Budding Arts Dance Group and the Halesworth Shotokan Karate Group. There will be various stalls and attractions, refreshments in the Garden Room, Bar-B-Q, Punch & Judy, Kiddies Corner, Face Painting, Parravani and much more. Kindly returning again this year to compere the afternoon is Dudley Clarke. If anyone would like to run a stall on our behalf, or book a table for themselves at a cost of £10, please call (01986) 872804. If anyone requires transport please call (01379) 588418. We will be outside the Co-operative food store selling draw tickets on Saturday 10th May, and look out for us at the Wednesday markets during May. Spectra Packaging are kindly sponsoring our first prize of £250, with many more prizes and cash prizes to be won.
We have been invited by Halesworth Volunteer Centre to join them at the pop up shop from 15th May. Come along to find out more about the League of Friends and how you can become involved, as well as learning more about other volunteering opportunities locally, and other local groups and organisations.


text:
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Home > News and Publications > For the Media > News Release Archive
The Johns Hopkins University & IOCB Prague Extend Their Collaboration to Include Joint Postdoctoral Training - 11/15/2016
The Johns Hopkins University & IOCB Prague Extend Their Collaboration to Include Joint Postdoctoral Training
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Johns Hopkins & IOCB Prague Collaborate on Joint Postdoctoral Training - Click to Tweet
The Johns Hopkins University (JHU) School of Medicine and Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) have extended their collaboration in translational research, which started in 2015, to include a joint postdoctoral fellowship training program.
The parties are promoting academic exchange by allowing selected postdoctoral fellows to conduct collaborative research in drug discovery and translational research at the partner institution: Johns Hopkins University School of Medicine will host postdoctoral fellows from IOCB and IOCB will host postdoctoral fellows from JHU for a minimum period of two years. Research projects will be mainly in the fields of chemistry, drug metabolism, pharmacokinetics, assay development and screening.
"I'm very happy that our collaboration with JHU brings yet another fruit," says Zden?k Hostomský, Ph.D., director of the IOCB Prague. "Apart from creating opportunities for young scientists to get new valuable experience from another top research institution, we expect that this synergy and combination of our chemistry capabilities with JHU's biology and drug discovery experience will boost the direct cooperation between our teams, accelerate our research efforts and finally bring real and important results in drug discovery field."
"The inaugural two years of our JHU-IOCB collaboration have been productive, leading to multiple joint publications patent filings," says Barbara Slusher, PhD, MAS, Professor of Neurology, Neuroscience, Psychiatry, medicine and Oncology at Johns Hopkins and the Director of Johns Hopkins Drug Discovery. "The new joint post-doctoral training program will further strengthen and broaden our interactions."
The Johns Hopkins Drug Discovery (JHDD) program at The Johns Hopkins University and IOCB Prague will work together to identify qualified candidates for the exchange. Visiting fellows will be provided with laboratory space and supplies for their project as well as granted with an annual stipend, total sum of which will be based on the rules of hosting institution and will be equally born by IOCB and the Johns Hopkins University.
Johns Hopkins and IOCB Prague started their collaboration in 2015 when they have entered into a five-year drug discovery research agreement to develop small-molecule and peptide drugs for a range of therapeutic areas including neurological diseases, cancer and gastrointestinal disorders.
The IOCB Prague, Czech Republic, performs fundamental research in organic chemistry, biochemistry and related disciplines oriented, in part, to medicinal applications. Among others, the HIV therapy blockbuster Tenofovir TM originated at IOCB Prague. The JHDD represents a Pharma-experienced team of drug discovery scientists tasked with identifying novel drug targets arising from Johns Hopkins faculty research and translating them into new small molecule drug therapies. The collaboration brings together the significant expertise and experience in medicinal chemistry at IOCB Prague with the biological target ideas, screening assays, animal pharmacology, drug metabolism and pharmacokinetics expertise at JHDD.
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text:
Q: react - hide/show DOM - using react library I am facing issue around with React.js for the first time and cannot find a way to show or hide something on a page via click.
I am not loading any other library to the page, so I am looking for some native way using the React library. This is what I have so far. I would like to show the results div when the click event fires.
Any help appreciated
var Detail = React.createClass({
    handleClick: function (event) {
        console.log(this.prop);
    },
    render: function () {
        return (

                <input type="submit" value="Search" onClick={this.handleClick} />

        );
    }
});

var DataRes = React.createClass({
    render: function () {
        return (

                Some Data

        );
    }
});

React.renderComponent(<Detail /> , document.body);

A: You can try below code :
In this example, you can try click on button and show you component and again click tyhen it will hide, basically its toggle,
Hope this is usefull for you.
var Detail = React.createClass({
    getInitialState: function() {
        return { show: false };
    },
    onClick: function() {
        this.setState({ show: !this.state.show }); // Here is the toggle
    },
    render: function() {
        return (

                <input type="submit" value="Search" onClick={this.onClick} />
                { this.state.show ? <DataRes /> : null } // basically this line will show your datas component view when you click on view

        );
    }
});

var DataRes = React.createClass({
    render: function() {
        return (

                Some Data

        );
    }
});

ReactDOM.render( <Detail /> , document.getElementById('container'));

redpajama_set_name: RedPajamaStackExchange


text:
The R313 is a Regional Route in South Africa that connects Prieska with the N8 between Griquatown and Groblershoop.

External links
 Routes Travel Info

Regional Routes in the Northern Cape

redpajama_set_name: RedPajamaWikipedia


"Ten heavy bombers (B-52, B-1B and B-2) flew in while the GPS was off and tested their skills at navigating without GPS..."
"It was found that without GPS the younger troops, sailors and pilots could still do it old school and seemed to relish the challenge."
Wonder if there is room to retrofit one of these in a B1?
For an aircraft, couldn't you use radar mapping to get a very good fix if you were overflying a know area? This is how TERCOM worked. In that case the waypoints would be very specific, but I would have thought strategic bombers now adays could carry the radar imagery of an entire theater for reference purposes. This would mean illuminating your radar, but depending on the threat or stand off range, that would be acceptable in most situations. If nothing else, it might allow precise terminal weapon delivery and presumably the gig is up once you start releasing weapons anyway.
Arctic nav is a real headache, even with GPS. Radio get really screwy towards the poles.
Edited by Josh, 05 December 2018 - 1031 AM.
I wasn't implying it should be a singular source of navigation, but it would allow PGM delivery where as most other nav methods short of GPS would not. Presumably you could refine your position when you made landfall.
Besides the bad radio conditions, I was under the impression GPS orbits were sub optimal for good coverage over the poles as well.
First of all, how accurate is a modern, high end INS over say an hour? If you then have something like a sniper pod it could update your INS in clear weather by locking onto an object of known location and tracking and ranging it. Alternately, with two such pods you could do it passively by triangulation.
I found one source claiming that "modern" INS used by aircraft drift by c. 0.6 nautical miles per hour. That's lousy for even a strategic weapon used over the poles, but it would get a human crew within sight and certainly within radar range of known objects to get a fix on even after a transpolar flight. RC135s use celestial to update their INS. I wonder how accurate that is?
It was certainly adequate for civilian airliners flying the Atlantic or the Pacific until the not too distant past. Or at least was, assuming it wasn't flown by a South Korean.
Its worth remembering that RAF Black Buck operations would also have been flown near exclusively by INS. I seem to recall the Black Buck Vulcans were fitted with an INS system that had been removed from VC10's awaiting conversion into RAF Tankers. Thats 3300 nautical miles.
You can't rely on GPS at high latitudes, either.
KC-135s no longer carry dedicated navigators, though the mount for celestial nav is still in the roof. As far as I know, celestial navigation is no longer used aboard US aircraft.
I was harking back to a FAMFLIGHT I took on a KC-135 back around '05 or so. The fitting for the navigator's sextant was still in the flight deck overhead, but the actual flying/navigating was done by the pilot/copilot.
I'm sure the automated systems are much faster and more accurate.


text:
Substance Abuse Causing Many Issues in Prisons Across the UK
Locked In
Ruined Routine
Easily Obtainable Drugs
Developing an Addiction
Additional Information for Addicts
Millions of people around the world will fall victim to substance abuse at some point during their life; some will continually abuse their substance of choice. This can lead to an addiction that will take over their life completely. For those that do not abuse drugs or alcohol, it can be puzzling to think why someone would ruin their life by abusing substances. However, it is not always that simple; addiction is an illness that can consume the life of the individual without this affected person even realising. The individual may begin to act in a selfish manner that can cause frustration to loved ones who have to try to deal with their addicted family member or friend.
Leading on from this, it would be safe to assume that many people believe that those who go to prison for whatever reason will not have any access to drugs. Nonetheless, it is becoming ever more apparent that drugs are easily accessible in prison, resulting in prisoners being allowed to continue with their illicit substance abuse (or even forming an addiction). Riots have broken out in a Birmingham prison recently because of this substance abuse, and this is causing concern among top prison and government officials.
Former prisoner Ricky Wood has spoken out about how G4S had 'lost control' of Birmingham Prison, as many of the inmates had fallen victim to substance abuse, therefore making them 'really unpredictable'. Ricky himself nearly overdosed after taking the drug known as Black Mamba while inside the prison. He said, "It's changing them [the prisoners] in dangerous ways and causing problems with debts and bullying. A mob mentality takes over when trouble breaks out. It's a different world, but G4S has lost control of that world. Prison officers are being overpowered both physically and psychologically by some of these people."
Ricky had been imprisoned for twenty weeks after harassing a previous partner. He was freed just as a riot broke out earlier in December; the wing he had been placed in was not involved in the riots, but it did mean that he faced being kept in the jail for longer than planned. "We were being told that even the staff were being locked in. It was pretty clear something major was happening. We were hearing bits and bobs of information in our wing and some lads were getting phone calls from some of those involved," he explained.
Rioters burned documents, stole keys and cut their way through chains in what was described as the 'worst prison disorder for more than twenty years'. Prisoners called the Birmingham Mail from inside the prison and explained that the riots broke out because a lack of staff meant that inmates were not given gym or exercise time. Inmates also claimed that the TV had not been working for days and they complained about the quality of the food given to them. Ricky added, "There are no staff, and that completely ruins the routine sometimes. The best meal I had in there was on that Friday evening because it didn't come from the usual kitchens. I'm not sure where it came from, and it was very late, but it was sweet and sour chicken."
It has been revealed that an inmate died due to a drug overdose while on the 'detox wing' in the prison last month. A post mortem showed that thirty-year-old Dean Boland had taken five different drugs that had not been prescribed. The official report into his death sparked major concerns about prescribed drugs being swapped between prisoners and the how easily obtainable these drugs are inside the Winson Green prison. Boland had been involved in heavy substance abuse from a young age, and at his time of death, was found to have traces of many drugs – that were not prescribed to him – in his system.
It would appear that substance abuse is a problem for many inmates in UK prisons, despite most people assuming that those behind bars would have no access to mood-altering substances. Substance abuse can affect anyone; it does not matter what age, race, religion or gender the individual is – addiction can take over their life as soon as the person loses control of their use. It can be incredibly easy to develop an addiction; the person may intend to take the substance 'just once', but this is often enough to become hooked. Once an individual has developed an addiction, he or she may face extreme difficulty overcoming this, and going back to a sober lifestyle can be a challenge. Overcoming an addiction requires great strength and determination, and this is an area in which many people fall down.
If you have concerns about a loved one's substance abuse, then contact us here at UK Rehab. We are a referral service that works alongside some of the UK's top treatment centres. These organisations have already helped countless thousands of individuals across the country, and are continuing to do so on a daily basis. They offer a range of treatments that are designed to help addicts overcome their addiction and keep it that way; this is why these facilities have such excellent success rates.
The staff in these clinics are fully trained individuals who will ensure that you feel comfortable and supported at all times; you can rest assured that you will never be judged by anyone in these centres. If this sounds like it could be for you, or you would like any additional information, then please, do not hesitate to get in touch with us. We will do everything in our power to help you overcome your addiction and help you to go on to lead a happy, healthy life.
Source: G4S has 'lost control' of riot-hit Birmingham Prison, says ex-inmate (Birmingham Mail)
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Coming to terms with the fact that you might need treatment for an alcohol addiction is never going to be easy. However, if you have allowed your use ...
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The current problems relating to prescription drug abuse is one that many people struggle to comprehend. It can be tough to come to terms with the fac...
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If you are affected by addiction yourself or are otherwise worried that someone you love might be, then your thoughts may be turning to addiction trea...


text:
Otto Kahler (* 13. Juli 1878 in Prag, Kaisertum Österreich; † 13. Juni 1946 in Freiburg im Breisgau) war ein österreichischer Hals-Nasen-Ohrenarzt, Laryngologe (Kehlkopfspezialist) und Hochschullehrer.

Leben und Werk
Otto Kahler war der Sohn des österreichischen Internisten und Pathologen Otto Kahler. Er studierte an der Universität Wien Medizin, promovierte 1902 zum Dr. med., war ab 1903 Assistent von Ottokar von Chiari und habilitierte sich 1909 für Laryngologe. Im Jahr 1912 wurde er als Nachfolger von Gustav Killian an die Albert-Ludwigs-Universität Freiburg berufen und 1919 zum ordentlichen öffentlichen Professor ernannt. Otto Kahler entwickelte die Tracheo-Bronchio-Ösophagoskopie weiter und forschte zur Problematik der gutartigen und bösartigen Neubildung des Kehlkopfes sowie dem Tonsillenproblem. Er gab gemeinsam mit Alfred Denker das Handbuch der Hals-, Nasen- und Ohrenheilkunde in neun Bänden heraus.

Otto Kahler wurde 1939 in der Sektion Oto-Rhino-Laryngologie als Mitglied in die Deutsche Akademie der Naturforscher Leopoldina aufgenommen.

Literatur

Weblinks
 Mitgliedseintrag von Otto Kahler bei der Nationalen Akademie der Wissenschaften Leopoldina

Anmerkungen und Einzelnachweise

Mediziner (20. Jahrhundert)
HNO-Arzt
Hochschullehrer (Albert-Ludwigs-Universität Freiburg)
Mitglied der Leopoldina (20. Jahrhundert)
Absolvent der Universität Wien
Person (Cisleithanien)
Österreicher
Geboren 1878
Gestorben 1946
Mann


350 New Orleans – Captain Planet of 350 Louisiana arrested in #FloodWallStreet!
Captain Planet of 350 Louisiana arrested in #FloodWallStreet!
Captain Planet was one of approximately 100 activists arrested on Wall Street after the People's Climate March. Wall Street is funding the climate crisis, a fact that protestors hoped to call attention to through direct action.


text:
Q: beginner-deploying jsf web application to Elastic Beanstalk I am working to create a java web application that uses Java Server Faces (JSF) version 2.1 along with CDI.
Can such a web app be deployed to Elastic Beastalk? I cannot see any option for JBOSS AS 7 (the latest version of JBOSS) so I am a bit confused... Which server do I choose from amongst the options shown in Elastic Beanstalk?

A: Amazon Elastic Beanstalk currently supports only Apache Tomcat for Java Applications. You can deploy an application to Tomcat 6 or 7 using the AWS toolkit for eclipse.
If you are looking for JBOSS you can try OpenShift from RedHat. You can deploy on either JBOSS AS 7 or JBOSS EAP 6 application servers
See alse:

*

*http://aws.amazon.com/elasticbeanstalk/faqs/

*http://docs.amazonwebservices.com/elasticbeanstalk/latest/dg/create_deploy_Java.sdlc.html

*http://www.jboss.org/openshift.html


text:
2017 Toyota Hilux SR5 4x2 revealed as part of range shake-up
By David Bonnici, 21 Sep 2017 Car News
A two-wheel-drive version of the range-topping Toyota Hilux dual cab ute, tweaked to reflect growing popularity with private buyers, has been added to the range
THE big-selling Toyota Hilux range has introduced even more variants including a two-wheel-drive 'Hi-Rider' version of the popular SR5 dual cab pick-up.
Seven new variants are added to the already diverse Toyota Hilux range including three SR extra cab-chassis variants (six-speed manual and auto) with the 2.8-litre turbo-diesel engine, three extra automatic Hi-Rider 4x2 pick-ups (a WorkMate double cab, SR extra cab and SR5 double cab), and an entry-level WorkMate grade (auto) for the 4x4 double cab-chassis.
Toyota Australia sales and marketing executive director Tony Cramb said the range revamp reflected the spread of the Hilux brand from fleet and trade sales to the private market – a trend that had helped it to top Australian vehicle sales in 2016, and lead sales nationally so far in 2017.
The shift also saw automatic Toyota Hilux models outsell manuals for the first time last year, leading Toyota to offer 17 self-shifters compared to the 12 previously on offer.
"Last year – for the first time – automatics accounted for more than half of all Hilux sales and this year the proportion has risen to almost 60 per cent and we expect it to increase further," Cramb said.
"We are also experiencing greater-than-expected demand for the two-wheel-drive Hi-Rider, so we have expanded our competitively priced offerings from three to five."
Cramb said the Hi-Rider appealed to buyers who did not need serious off-road capability, but appreciate the same looks and ground clearance as a 4x4 Hilux, half of which were SR5 variants.
The new SR5 Hi-Rider double cab comes with the same 130kW/420Nm 2.8-litre four-cylinder turbo-diesel engine with a six-speed automatic transmission, and is priced at $49,490 – $6950 less than the 4x4 version.
As well, 4x4 SR dual-cab pick-up buyers will now have satellite navigation and alloy wheels as a $2000 option without the need to step up to the range-topping SR5 – the SR double cab manual with the option would cost $48,560 compared with $54,440 for the SR5 manual.
Some of the low-selling 4.0-litre V6 petrol HiLux models are discontinued, meaning the number of Hilux variants to choose from remains at 31. Of these 23 are workmanlike one-tonners that include all 4x2 variants and all 4x4 single and extra cabs.
Meanwhile, SR and SR5 models receive minor enhancements and price changes. SR 4x4 double cabs gain downhill assist control, PVC flooring and black door handles for an extra $70, while SR5 prices go up $50 but gain LED fog lamps.
SR extra cab pick-ups and SR5 variants also gain a tailgate lock.
Most of the updated Hilux line-up goes on sale from October 6, with the changes to existing SR and SR5 models available now.
The current-generation Toyota Hilux is not expected to be replaced until around 2025.
2017 Toyota Hilux variant additions pricing
Hi-Rider SR 4x2 Extra Cab (pick up) 2.8L turbo-diesel, auto - $40,190
Hi-Rider WorkMate 4x2 Double Cab (pick-up) 2.4L turbo-diesel, auto - $39,490
Hi-Rider SR5 4x2 Double Cab (pick-up) 2.8L turbo-diesel, auto - $49,490
Workmate 4x4 Extra Cab (cab chassis) 2.4L turbo-diesel, auto - $42,490
SR 4x4 Extra Cab (cab chassis) 2.8L turbo-diesel, manual - $42,910
SR 4x4 Extra Cab (cab chassis) 2.8L turbo-diesel, auto - $44,910
SR5 4x4 Extra Cab (pick-up) 2.8L turbo-diesel, auto - $54,440
WorkMate 4x4 Double Cab (cab chassis) 2.4L turbo diesel, auto - $44,490
Toyota builds Ranger Raptor rival Aussies can't buy
By Cameron Kirby | 30 Sep 2020
What would win in a fight, a Raptor or a Mako? New Zealand is about to find out
Fernando Alonso gets first thrash of the 2021 Toyota HiLux
By Tim Robson | 01 Jun 2020
An updated and more powerful HiLux looms. Has Toyota done enough to keep it ahead of the Ford Ranger?
More power for Hilux Rugged X and Rogue
By Matt Raudonikis | 28 Sep 2020
Toyota's locally developed halo models receive performance and equipment upgrades.
Facelift and more power for updated Toyota Hilux
By Matt Raudonikis | 13 Aug 2020
There's nothing like some fresh competition to improve the breed.
Is this the 2021 Toyota Hilux?
Updated Toyota Hilux gets a big power boost
2020 Toyota HiLux SR5+ review
2021 Toyota HiLux review
2020 Toyota HiLux Rogue review


Matthew S. McKee recently obtained a favorable decision and order on March 23, 2011 from a workers' compensation judge in Philadelphia County, Pennsylvania which granted the Termination Petition and denied the Review Petition. The Judge accepted the Employer's legal argument and determined Claimant fully recovered from her work injury.
This was a significant decision since Claimant sustained an acknowledged work injury on January 20, 2005 and she continued to receive workers' compensation benefits. The Judge rejected Claimant's testimony as generally not credible. The Judge accepted the testimony of the Employer's two (2) medical experts, Dr. John Duda and Dr. Gilbert Tausch over the testimony of Claimant's medical experts, Dr. Michael Cohen and Dr. Richard Kaplan. The Judge rejected Dr. Kaplan's testimony regarding the nature of the work injury as not credible. Further, the Judge found Dr. Kaplan's opinion about the work related diagnoses not credible because, in part, he did not review any diagnostic studies to support his opinion. The Judge also rejected Dr. Cohen's testimony regarding the work injury as not credible since there was no credible evidence Claimant hit her head or lost consciousness on January 20, 2005. The Judge denied in its entirety the Review Petition. Moreover, the Judge accepted Dr. Duda's conclusions that Claimant fully recovered from her work injury and Dr. Tausch's opinions that Claimant did not sustain a head injury.
This favorable decision resulted in an immediate cessation of Claimant's indemnity benefits plus Claimant's entitlement to ongoing medical benefits were also denied by the Judge.
Matthew S. McKee has practiced in the field of workers' compensation for more than ten years representing employers and insurance companies throughout Pennsylvania. He has developed extensive experience handling a wide range of litigation matters including motor vehicle, premises liability, products liability, medical malpractice, and workers' compensation. Mr. McKee is admitted to practice law in all Pennsylvania State Courts.


text:
PDP, European Union Election Observation Mission react to El-Rufai's alleged death threat
The Peoples Democratic Party (PDP) in its reaction to the controversial statement of Governor Nasir El-Rufai of Kaduna State threatened to pull out of the peace accord signed by political parties ahead of the forthcoming general elections.
Mr. Kola Ologbondiyan, the spokesman of the PDP in a press conference in Abuja on Wednesday said that the PDP will be left with no option but to consider a review of its signatory to the peace accord if no action was taken over El-Rufai's statement.
"Nigerians are still in a state of shock over comments by el-Rufai on the national television that members of the global democratic institutions that are working for peaceful elections in Nigeria would return to their countries in body bags. What a threat?
"We call on the international community to immediately impose a travel ban on el-Rufai for this inciting comment against peaceful elections in our country."
European Union Mission reacts to El-Rufai's statement
Also, the European Union Election Observation Mission in its reaction to the statement said that it has strict code of conduct and its observers do not interfere in elections.
READ OUR POST: 4 APC members in the House of Representatives dumps ruling party
The statement by the foreign observers was released on Wednesday by Sarah Fradgley, its Press and Public Outreach Officer.
"We are aware of the comments by the Governor of Kaduna about non-interference by foreigners during a talk show on the elections on Tuesday.
"While the security of EU observers is of paramount importance, and will remain under constant review, EU observers will continue their work across the country in the run-up to – and beyond – the elections."
Governor El-Rufai had during a programme on NTA said;"Those that are calling for anyone to come and intervene in Nigeria, we are waiting for the person that would come and intervene, they would go back in body bags," he said.
Nigerian Newspapers Review (Thursday, 07 February, 2019 Edition)
Nigerian Newspapers Review (Friday, 08 February, 2019 Edition)


text:
Suggested Reading May 4, 2020
May 4, 2020 May 10, 2020 Linda Reimer
Hi everyone, here are our recommended titles for the week, and while the library is closed the weekly recommendations will all be digital – eBooks & downloadable audiobooks available through the Digital Catalog.
The Accusers by Lindsey Davis (Format: eBook)
Fresh from his trip to Britain, Marcus Didius Falco needs to re-establish his presence in Rome. A minor role in the trial of a senator entangles him in the machinations of two real life lawyers at the top of their trade. The senator is convicted, but then dies, apparently by suicide. It may have been a legal move to protect his heirs, but Falco is hired to prove it was murder. As Falco shows off his talents in the role of advocate, he exposes himself to a tangle of upper-class secrets and powerful elements in Roman law that may have consequences he hadn't quite bargained for.
All the Flowers in Paris: A Novel by Sarah Jio (Format: eBook)
When Caroline wakes up in a Paris hospital with no memory of her past, she's confused to learn that for years she's lived a sad, reclusive life in a sprawling apartment on the rue Cler. Slowly regaining vague memories of a man and a young child, she vows to piece her life back together—though she can't help but feel she may be in danger. A budding friendship with the chef of a charming nearby restaurant takes her mind off her foggy past, as does a startling mystery from decades prior.
In Nazi-occupied Paris, a young widow named Céline is trying to build a new life for her daughter while working in her father's flower shop and hoping to find love again. Then a ruthless German officer discovers her Jewish ancestry and Céline is forced to play a dangerous game to secure the safety of her loved ones. When her worst fears come true, she must fight back in order to save the person she loves most: her daughter.
When Caroline discovers Céline's letters tucked away in a closet, she realizes that her apartment harbors dark secrets—and that she may have more in common with Céline than she could have ever imagined.
All the Flowers in Paris is an emotionally captivating novel rooted in the resiliency and strength of the human spirit, the steadfastness of a mother's love, and the many complex layers of the heart—especially its capacity to forgive.
"Heart-stopping . . . Fans of emotional, romantic stories set during World War II will enjoy this heartbreaking tale of love and loss."—Booklist
Chemistry: A Novel written by Weike Wang and read by Julia Whelan (Format: Audiobook)
A luminous coming-of-age novel about a young female scientist who must recalibrate her life when her academic career goes off track; perfect for readers of Lab Girl and Celeste Ng's Everything I Never Told You.
Three years into her graduate studies at a demanding Boston university, the unnamed narrator of this nimbly wry, concise debut finds her one-time love for chemistry is more hypothesis than reality. She's tormented by her failed research—and reminded of her delays by her peers, her advisor, and most of all by her Chinese parents, who have always expected nothing short of excellence from her throughout her life. But there's another, nonscientific question looming: the marriage proposal from her devoted boyfriend, a fellow scientist, whose path through academia has been relatively free of obstacles, and with whom she can't make a life before finding success on her own. Eventually, the pressure mounts so high that she must leave everything she thought she knew about her future, and herself, behind. And for the first time, she's confronted with a question she won't find the answer to in a textbook: What do I really want? Over the next two years, this winningly flawed, disarmingly insightful heroine learns the formulas and equations for a different kind of chemistry—one in which the reactions can't be quantified, measured, and analyzed; one that can be studied only in the mysterious language of the heart. Taking us deep inside her scattered, searching mind, here is a brilliant new literary voice that astutely juxtaposes the elegance of science, the anxieties of finding a place in the world, and the sacrifices made for love and family.
Continental Crimes by Martin Edwards (Format: eBook)
A man is forbidden to uncover the secret of the tower in a fairy-tale castle by the Rhine. A headless corpse is found in a secret garden in Paris – belonging to the city's chief of police. And a drowned man is fished from the sea off the Italian Riviera, leaving the carabinieri to wonder why his socialite friends at the Villa Almirante are so unconcerned by his death.These are three of the scenarios in this new collection of vintage crime stories. Detective stories from the golden age and beyond have used European settings – cosmopolitan cities, rural idylls and crumbling chateaux – to explore timeless themes of revenge, deception, murder and haunting.Including lesser-known stories by Agatha Christie, Arthur Conan Doyle, G.K. Chesterton, J. Jefferson Farjeon and other classic writers, this collection reveals many hidden gems of British crime.
The Family Upstairs: A Novel by Lisa Jewell (Format: eBook)
"Rich, dark, and intricately twisted, this enthralling whodunit mixes family saga with domestic noir to brilliantly chilling effect." —Ruth Ware, New York Times bestselling author
"A haunting, atmospheric, stay-up-way-too-late read." —Megan Miranda, New York Times bestselling author
From the New York Times bestselling author of Then She Was Gone comes another page-turning look inside one family's past as buried secrets threaten to come to light.
Be careful who you let in.
Soon after her twenty-fifth birthday, Libby Jones returns home from work to find the letter she's been waiting for her entire life. She rips it open with one driving thought: I am finally going to know who I am.
She soon learns not only the identity of her birth parents, but also that she is the sole inheritor of their abandoned mansion on the banks of the Thames in London's fashionable Chelsea neighborhood, worth millions. Everything in Libby's life is about to change. But what she can't possibly know is that others have been waiting for this day as well—and she is on a collision course to meet them.
Twenty-five years ago, police were called to 16 Cheyne Walk with reports of a baby crying. When they arrived, they found a healthy ten-month-old happily cooing in her crib in the bedroom. Downstairs in the kitchen lay three dead bodies, all dressed in black, next to a hastily scrawled note. And the four other children reported to live at Cheyne Walk were gone.
In The Family Upstairs, the master of "bone-chilling suspense" (People) brings us the can't-look-away story of three entangled families living in a house with the darkest of secrets.
Interior Chinatown: A Novel written by Charles Yu and read by Joel de la Fuente (Format: Audiobook)
"One of the funniest books of the year has arrived, a delicious, ambitious Hollywood satire." —The Washington Post
From the infinitely inventive author of How to Live Safely in a Science Fictional Universe comes a deeply personal novel about race, pop culture, immigration, assimilation, and escaping the roles we are forced to play.
Willis Wu doesn't perceive himself as a protagonist even in his own life: He's merely Generic Asian man. Sometimes he gets to be Background Oriental Making a Weird Face or even Disgraced Son, but he is always relegated to a prop. Yet every day he leaves his tiny room in a Chinatown SRO and enters the Golden Palace restaurant, where Black and White, a procedural cop show, is in perpetual production. He's a bit player here, too, but he dreams of being Kung Fu Guy—the most respected role that anyone who looks like him can attain. At least that's what he has been told, time and time again. Except by one person, his mother. Who says to him: Be more.
Playful but heartfelt, a send-up of Hollywood tropes and Asian stereotypes, Interior Chinatown is Charles Yu's most moving, daring, and masterly novel yet.
The Lowland by Jhumpa Lahiri (Format: eBook)
From the Pulitzer Prize-winning, best-selling author of The Namesake comes an extraordinary new novel, set in both India and America, that expands the scope and range of one of our most dazzling storytellers: a tale of two brothers bound by tragedy, a fiercely brilliant woman haunted by her past, a country torn by revolution, and a love that lasts long past death.
Born just fifteen months apart, Subhash and Udayan Mitra are inseparable brothers, one often mistaken for the other in the Calcutta neighborhood where they grow up. But they are also opposites, with gravely different futures ahead. It is the 1960s, and Udayan–charismatic and impulsive–finds himself drawn to the Naxalite movement, a rebellion waged to eradicate inequity and poverty; he will give everything, risk all, for what he believes. Subhash, the dutiful son, does not share his brother's political passion; he leaves home to pursue a life of scientific research in a quiet, coastal corner of America.
But when Subhash learns what happened to his brother in the lowland outside their family's home, he goes back to India, hoping to pick up the pieces of a shattered family, and to heal the wounds Udayan left behind–including those seared in the heart of his brother's wife.
Masterly suspenseful, sweeping, piercingly intimate, The Lowland is a work of great beauty and complex emotion; an engrossing family saga and a story steeped in history that spans generations and geographies with seamless authenticity. It is Jhumpa Lahiri at the height of her considerable powers.
The Man with a Load of Mischief by Martha Grimes (Format: eBook)
Long Piddleton had always been wary of newcomers. But the quiet town was stunned when the first stranger was found dead, upended in a butt of ale in the cellar of the Men with a Load of Mischief. Then the second body appeared, swinging in place of the mechanical man above the door of the Jack and Hammer.
Suddenly Long Piddleton had good reason to be wary of everyone! Its cozy pubs and inns with their polished pewter and blazing hearths had become scenes of the most bizarre crimes. Who were the victims? And who was the murderer? A stranger? A maniac? Or the disarmingly friendly man next door?
Richard Jury Series, Book 1
Please See Us by Caitlin Mullen (Format: eBook)
In this sophisticated, suspenseful debut reminiscent of Laura Lippman and Chloe Benjamin, two young women become unlikely friends during one fateful summer in Atlantic City as mysterious disappearances hit dangerously close to home.
Summer has come to Atlantic City but the boardwalk is empty of tourists, the casino lights have dimmed, and two Jane Does are laid out in the marshland behind the Sunset Motel, just west of town. Only one person even knows they're there.
Meanwhile, Clara, a young boardwalk psychic, struggles to attract clients for the tarot readings that pay her rent. When she begins to experience very real and disturbing visions, she suspects they could be related to the recent cases of women gone missing in town. When Clara meets Lily, an ex-Soho art gallery girl who is working at a desolate casino spa and reeling from a personal tragedy, she thinks Lily may be able to help her. But Lily has her own demons to face. If they can put the pieces together in time, they may save another lost girl—so long as their efforts don't attract perilous attention first. Can they break the ill-fated cycle, or will they join the other victims?
Evocative, eerie, and compelling, Please See Us is a fast-paced psychological thriller that explores the intersection of womanhood, power, and violence.
The Stranger Diaries by Elly Griffiths (Format: eBook)
Finalist for an Edgar Award for Best Novel
"This lively whodunit keeps you guessing until the end." —People
Death lies between the lines when the events of a dark story start coming true in this haunting modern Gothic mystery, perfect for fans of Magpie Murders and The Lake House.
Clare Cassidy is no stranger to murder. A high school teacher specializing in the Gothic writer R. M. Holland, she even teaches a course on him. But when one of Clare's colleagues is found dead, with a line from Holland's iconic story "The Stranger" left by her body, Clare is horrified to see her life collide with her favorite literature.
The police suspect the killer is someone Clare knows. Unsure whom to trust, she turns to her diary, the only outlet for her suspicions and fears. Then one day she notices something odd. Writing that isn't hers, left on the page of an old diary:
Hallo Clare. You don't know me.
Clare becomes more certain than ever: "The Stranger" has come to terrifying life. But can the ending be rewritten in time?
Be well and happy reading!
Linda Reimer, SSCL
Note: Book summaries are from the publisher unless otherwise specified.
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Published by Linda Reimer
I am a librarian at The Southeast Steuben County Library in Corning, New York, where we love books, technology and life-long learning for patrons and ourselves too! View all posts by Linda Reimer
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Uncovered Videos Show London's Muslim Mayor Calling Moderate Muslims Uncle Tom's & Defending Convicted Terrorists
Barracuda Brigade 2017-06-06
06 Jun 2017 Barracuda Brigade
People with active brain cells recognize who and what London's Muslim Mayor Sadiq Khan is and why he and other Muslims work so hard to get into elected offices. According to numerous Imams, it is just part of the plan to take over.
When is England going to get a clue that Muslim extremists are infiltrating their political system? Was his intention to get into a political office only to cause harm?
Video Screenshot
100%FedUp: London's Muslim Mayor Sadiq Khan, called on the British government today to cancel their visit with President Donald Trump.
Speaking to Channel 4 news, Khan felt Trump's out-of-context criticisms and continued attacks on Twitter meant that the U.K. should not "roll out the red carpet" for the president as "his policies go against everything we stand for."
He added: "When you have a special relationship it is no different from when you have got a close mate. You stand with them in times of adversity but you call them out when they are wrong. There are many things about which Donald Trump is wrong." –Hollywood Reporter
Trending: Sebastian Gorka: Shocking Trump Russia Investigation Memo Only The Beginning & Calls for This!
Shouldn't London's government be more concerned with their current mayor's past than of President Trump's efforts to unify the world in the fight against extreme Islamic terrorism?
In 2016, the now Mayor of London, Sadiq Khan was branded unfit to be London's Mayor after it emerged that he had described moderate Muslim groups as 'Uncle Toms' – a notorious racial slur used against black people to suggest that they are subservient to whites.
The incendiary claim emerged in a 2009 interview with Iranian-backed Press TV, when Mr Khan was 'minister for community cohesion', in charge of Government efforts to stamp out extremism.
The revelation is a major blow for Mr Khan, who has faced a string of claims about his past dealings with Muslim extremists during the bitter campaign to succeed Boris Johnson. –Daily Mail
Watch the 2009 video here:
That's not the only video that should make every London citizen be concerned about their Mayor's radical views. A 2002 video has emerged showing Sadiq Kahn defending convicted Islamic terrorists who attempted to revive the Islamic Liberation Party in Egypt.
The video, via Josh Caplan of Vessel News, shows Khan defending terrorists. At the beginning of the video, Muslims in the street shout "Allahu Akbar!" –GP
In the video, London's current Muslim Mayor can be seen defending convicted Muslim terrorists: "There is no evidence at all against the three British men, the only evidence against them is these confessions. We now have unequivocal proof that the confessions were obtained under duress and under torture – as there is no evidence against the men, the men need to be released straight away and sent back home to their families.
The Egyptian government and the state prosecutor have made a terrible mistake. They can correct that mistake by releasing the men now . . . What we're concerned about is they're compounding their mistake by continuing to detain them and having this farce of a trial, this is in breech of Egyptian's [sic]own very important law, it has a proud history of being the custodians of law and justice . . ."
Rare clip from '02 shows then lawyer Sadiq Khan defending convicted terrorists who attempted to revive the Islamic Liberation Party in Egypt pic.twitter.com/gMS9NIYxMQ
— Josh Caplan (@joshdcaplan) June 6, 2017
Tags:Muslims
German Woman ARRESTED & Hit With HUGE Fine For Posting Anti-Immigrant Joke On Facebook
Devin Nunes: Probable Cause Of Abuse Of Power By Members Of Obama Admin, Subpoenas Just Beginning
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A bus crash Wednesday dawn has killed three persons in the Western Region and left several others seriously injured.
The Elubo-bound bus, which was travelling from Aflao in the Volta Region, collided head on with a tipper truck between Beposo and Assorko Essamun at a spot where a speed ramp is being constructed by the Ghana Highway Authority.
It is unclear what caused the accident at about 4:15am but many suspect it might have been the results of the ongoing ramp construction since one side of the road had been blocked.
Western Regional MTTD boss, Chief Superintendent Richard Appiah, who confirmed the accident to 3news said the deceased and the injured been taken to the St Benedict Hospital and Effia-Nkwanta Hospital respectively for treatment.There were 53 passengers on the bus with registration number Freedom 1 -15, the Police MTTD said. Both the bus and the tipper truck registered GE 3350-14, which was traveling from Inchaban area towards Beposo, have been towed from the road for free flow of traffic.
The post [Photos] 3 killed as Elubo-bound bus collides with tipper truck appeared first on 3newsgh.


N6-Methyladenosine (m6A) modification is hypothesized to regulate processes such as for example RNA degradation localization and splicing. individual cells unveils Rabbit polyclonal to cytochromeb. a structural changeover at methylated adenosines using a propensity to single-stranded framework next to the improved base. Launch Post-transcriptionally modified bases in RNA are essential and numerous to cellular function. The most frequent internal RNA adjustment in eukaryotes is normally adenine N6-methylation (Amount 1) 1 which takes place typically at three sites per mRNA and is available on lengthy noncoding RNAs aswell.2 3 Amounts of substitutions per RNA change from one to as much as 11 or even more. Although the result of methylation in codons on translation provides yet to become driven methylation loci take place mostly in 3′ UTRs and near splice sites recommending a far more common function in signaling and control instead of directly in proteins coding. Within this light methylation provides been proven to shorten the common duration of RNAs also to impact their subcellular localization.4 Significantly the result of the substitution on RNA framework and folding isn't known for just about any from the a large number of RNAs which contain the adjustment. Amount 1 conformations and Buildings of m6A in RNA. (A) methyl orientation is normally preferred over when the bottom is unpaired16 due to Cyclamic Acid a steric clash between your methyl group and N7. (B) Space-filling types of m6A in and conformations (N9 substituent … Although this RNA adjustment has been examined for many years the biology and biochemistry of m6A methylation and demethylation is normally emerging rapidly lately. A methylation complicated including enzyme METTL3 continues to be identified and proven to perform adenine methylation in eukaryotic cells 5 6 and FTO and AlkBH5 are two oxidative proteins which have been proven to accomplish demethylation becoming energetically favored by ca. 1.5 kcal/mol over (Number 1).16 Consistent with this in the sound state it resides in orientation.17 The structure of the modified base in paired RNA is unfamiliar; in solitary strands it likely adopts the favored conformation 18 but in pairing positions this is not clear. Indeed simple inspection of foundation pairing models (Number 1C) suggests at least three possible constructions for m6A combined within duplexes. The query of which of these is created could well-affect pairing geometry and stability of folded RNAs and ultimately the biology of this changes. To study this question here we have carried out biophysical and structural studies of discrete m6A residues in short RNAs. We statement that solitary m6A modifications are destabilizing to RNA duplexes that contain them but in contrast they may be strongly stabilizing in unpaired positions adjacent to duplexes. We further show the N6 methylamino group must distort to a high-energy conformation revolving the methyl group into the major groove in order to be accommodated into a locally combined helix. This suggests that enzymatic methylation in combined regions of RNA Cyclamic Acid and conversely demethylation in unpaired areas could destabilize existing structure possibly triggering larger conformation changes in the RNA and altering its susceptibility to degradation. Initial data mapping the structure of methylated sites in cellular RNAs reveals the presence of a structural transition near the methylated adenosine consistent with the notion that m6A is definitely preferentially situated Cyclamic Acid in the transition between unpaired and duplex structure. EXPERIMENTAL SECTION RNA Synthesis RNA oligonucleotides were synthesized using standard β-cyanoethyl phosphoramidite chemistry and 2′-conformation. The NOEs observed in a Cyclamic Acid 100 ms combining time H2O SS-NOESY experiment for the methyl orientation. However the data clearly rule this out. Normal foundation stacking NOEs were observed from your sugars resonances of G2 and the sugars resonances of m6A to the conformation then the H1′/H8 NOE would be very intense but such a NOE is not observed. In addition moderate intensity NOEs were observed to the H1′ of U4 and C9 from your conformation. Further confirmation the projects of H2 and the H8 of inside a combined duplex using the methyl group aswell. (A) The common structure of the complete 10 bp duplexes using the MA in blue and unmodified DA RNA in crimson. ….
Tagged with: Cyclamic Acid, Rabbit polyclonal to cytochromeb.


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Smart Design Studio - Sydney Architects
Arlington Grove
Catalysed by the extension of Sydney's light rail to Dulwich Hill, and a consequential land rezoning for medium-density housing, Smart Design Studio's Masterplan for Arlington Grove has delivered a beautifully landscaped new residential precinct. This former industrial site has been converted into 246 well-planned apartments arrayed around a series of leafy courtyards and lanes. At an urban scale the site was conceived as an edge to Johnson Park which sits to the north-west and; at a finer grain, as a continuation of the orthogonal street network to the south-east.
The four buildings that make up the project are carefully located on the site to both contain the extensive landscaping, and to maximise the number of bright, sunny apartments with views over the district to the CBD skyline and the park. Their narrow footprints promote natural cross ventilation for the residences. The building heights are unified, sitting at either 4 storeys where they address the local streets or stepping up to 8 storeys towards Johnson Park. Brick was chosen as it's a naturally low maintenance material that adds texture and compliments both the neighbouring housing stock and the larger buildings of Dulwich Hill.
The architecture utilises carefully composed and simple, long elevations, their principles borrowed from classical buildings, framed by articulated corners. Contrasting the almost metronomic rhythm of the façades these corners provide dynamism and interest, creating a strong identity for each of the four buildings arrayed around the campus-like site. Expressed floor slabs serve a dual purpose, both supporting the leaves of brickwork along the façade and visually breaking the building into segments, by introducing a further note of play within the highly regular grid.
Two storey high colonnades have been placed around the perimeter of the courtyards. They connect via generous terraces directly to the squares, lanes and gardens of the site. The facades of the buildings are further articulated via deep brick blades which form a brise soleil, encouraging shadow play. The elegant vertical orientation of the brick blades also provides depth to assist in passive solar control, protecting building interiors from summer sun while allowing in low angled winter sun.
Each building has a clear address along the new publicly accessible private lanes and walkways within the accessible green spaces at ground level. Public benefits, such as "Arlington Square", a landscaped shared zone featuring a café and an extended, high quality ground plane, has transformed a dead end street into a vibrant urban place, marking the entrance to the new Arlington tram stop. A new GreenWay running parallel with the tramline provides informal native landscaping for the enjoyment of residents, neighbours and wildlife whilst forming a cycle path connection to Sydney CBD.
The interiors of the project bring the architecture inside and bring to the fore some of SDS's established interior design concepts, adapted to suit this project and location. The foundation for these simple and beautiful apartments is great planning to achieve generously sized apartments with tall ceilings.Simple orthogonal white interior spaces, reflecting the rhythm of the exteriors, are contrasted with gently splayed joinery elements which draw inspiration from the dynamic corners of the buildings.
The look is tailored and the palette is matt with charred wood veneer as the feature for the dark scheme and white over-painted wood for the light. These veneers are coupled with clay-stained wood, looped carpet, brushed stainless steel details, full height doors and very fine floating benchtops. Functional arrangements, high quality fixtures and fittings and energy efficient design create wonderful homes for people to live in, connected to the outdoors and the surrounding green space.
Dark brick fences at the base of the building extend the architecture into the surrounding open spaces. In addition to the landscaped courtyards and lanes, there are facilities that help to build a community – a shed to repair bikes and assemble furniture, a club room that can be booked for birthday parties or meetings and a barbeque area. A community garden is another asset, as are the fruit trees lining the laneways such as the "orange grove". Stemming from this concept each building bears the name of a different variety of orange.
ARCHITECTURE FROM THE INSIDE OUT
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© Smart Design Studio 2021


Jasmine Coley-Hartley and Emily Coe.
THE PARTNER of a man stabbed to death in Solihull has demanded justice for their daughter who 'asks for her dad every day'.
Leneto Kellengbeck, who leaves behind a daughter aged two, was found with critical injuries when police were called to Arran Way in Smith's Wood just after 11.15pm on Friday (March 29).
The 24-year-old, who lived nearby and was also known as Lenny, died a short time later.
His partner and mother of his child Emily Coe joined his mum Jasmine Coley-Hartley at a West Midlands Police press conference to appeal for the perpetrators to come forward.
Ms Coe said: "My daughter asks for her dad everyday. And I have to say to her; Daddy's not coming.
"Not only am I grieving for myself because I've lost my best friend and the person who supported me in every decision I made as a mother.
"Now I am a single mother who has to grieve for the man I share a child with.
"I have to grieve for my daughter because she's too innocent to understand.
"And we don't even have an inkling as to why this happened.
"We don't have any sort of answer, any sort of suspect. We have nothing.
"I won't rest until my daughter has justice for her dad.
No arrests have yet been made, but police say they are continuing to look for CCTV and speak to potential witnesses.
His mum Jasmine said: "Every day I come downstairs and start to cry first before I pray in the morning.
"I ask 'why Lenny? Why? Why did they take him away from me?
"They ripped my heart our. They turned my world upside down.
"Everybody's world is turned upside down at the minute, and they're asking for answers.
"The perpetrator should come forward and give themselves up.
"The police are doing the best they can.
Friends have set up a a Go Fund Me page to help Lenny's family following his death.
The page has raised nearly £7,000 in just two days.
Reece Johnson, who set up the page, wrote: "The most respectful young man you'll ever meet never harmed nobody always showed love to everyone.
"I've lost a best friend due to knife crime.