Insulin treatment for type 1 diabetes mellitus (T1D) has improved over the past decades due to advances in insulin formulations and administration techniques. Nevertheless, optimal glucose control and reaching HbA1c goals remain challenging for many patients. Consequently, the risk of subsequent micro- and macrovascular complications remains high and life expectancy is still reduced in this patient group so that there is an obvious need for improvement of current therapies or the development of new, additional treatments . So what else can be done?
A large body of current research focuses on potential adjunct therapies in type 1 diabetes, investigating a range of agents including SGLT2 inhibitors, GLP-1 receptor agonists, amylin analogues and others. To date, only pramlintide (Symlin®, AstraZeneca), an analogue of the pancreatic hormone amylin, has made it to the market, that is the US market only, in 2005. But which potential has this substance for therapy improvement in this patient group?
In contrast to healthy individuals, patients with T1D do not exhibit a significant amylin secretion or are even amylin deficient due to autoimmune destruction of β-cells. Natural amylin is produced by the β-cells and co-secreted with insulin in a fixed ratio in response to caloric intake. Interestingly, obese and non-obese individuals with impaired glucose tolerance also exhibit altered amylin secretion in a similar fashion as already recognised for insulin secretion (e.g. delayed and increased amylin secretion) .
This deficiency as well as the natural effects of amylin such as suppression of glucagon secretion, slowing of gastric emptying and regulating satiety suggests that amylin replacement therapy may have benefits in T1D therapy. Since amylin in its natural form is insoluble and tends to aggregate, the analogue pramlintide has been developed.
Clinical trials demonstrated that adjunct pramlintide to insulin therapy can decrease postprandial glucose excursions and improve HbA1c without weight gain .
Pramlintide has been studied thoroughly, but is it enough?
Postprandial hyperglycaemia was shown to be significantly reduced with pramlintide treatment in several trials. The time to maximum glucose concentration was prolonged, so that in combination with insulin pramlintide treatment can increase the risk of postprandial hypoglycaemia. In early trials, severe hypoglycaemia occurred after treatment initiation during the first 4-6 weeks [4, 5]. The effect of pramlintide on insulin doses has been studied in several trials suggesting that reduction of meal related bolus doses rather than basal insulin therapy needs to be adjusted [6, 7]. In order to prevent severe hypoglycaemia, the manufacturer recommends to reduce mealtime insulin doses up to 50% at treatment initiation.
Positive effects of pramlintide adjunct therapy on HbA1c was observed in randomised clinical trials with a treatment period up to 52 weeks with a difference of approx. -0.3% at treatment end compared to placebo [8, 9]. In addition, the trial by Whitehouse et al included an open-label extension period of one year, during which the HbA1c reduction could be sustained, suggesting that the effect on HbA1c is not only a temporary one. Noteworthy, three times more participants in the pramlintide group of this trial reached an HbA1c level of less than 7% compared to the placebo group.
However, the effect of pramlintide on HbA1c is not consistent throughout trials. The trial reported by Edelman et al did not observe a difference in HbA1c after 29 weeks of either pramlintide or placebo treatment (approx. -0.5% in both groups) . One difference of this trial compared to previous ones was that mealtime insulin doses were initially reduced by 30-50% in the pramlintide group. At the end of the treatment period, a reduction in total daily insulin doses (-12% pramlintide vs. +1% placebo) together with lower postprandial glucose values compared to placebo was observed.
The effect on body weight was comparable in the above-mentioned trials and patients lost weight in the pramlintide groups despite reductions in total daily insulin doses, while patients in the placebo groups gained weight. This weight loss is independent of nausea, a common transient site effect during the first 4-8 weeks of treatment. Ratner et al stratified the patients in their trial based on BMI and could show that the higher BMI group lost more weight compared to patients with a lower BMI . This suggests that pramlintide may have benefits particularly for overweight T1D patients.
Pramlintide is not widely used and as mentioned before only available on the US market. From early postmarketing data a high discontinuation rate within the first 2 months of treatment initiation was indicated as patients seemed to be disappointed about treatment effects (e.g. insufficient weight reduction, side effects, lack of effectiveness, complicated dosing) .
Due to its pharmaceutical properties, pramlintide cannot be mixed with other short-acting insulin formulations thus requiring an additional injection prior to meals. Moreover, in contrast to the physiologic co-release with insulin in a fixed ratio, dosing guidelines for pramlintide recommend a fixed dose of 30 or 60 µg in addition to varying insulin amounts, an approach that leads to an inconsistent dose ratio compared to physiological conditions.
The group around Riddle et al. tried to mimick near physiological conditions and administered a fixed-ratio of pramlintide and insulin (via two wearable pumps with subcutaneous delivery) to 34 subjects with T1D over 24 hours. A fixed ratio of 9µg pramlintide per IU of human insulin was selected based on a published computer simulation that calculated the optimal ratio for a co-formulation [4, 5]. This fixed ratio was compared to a placebo and insulin infusion. CGM measurements were collected in addition to laboratory measurements of BG over the 24-hour periods. Co-administration of pramlintide in the fixed dose-ratio resulted in blunted BG excursions after all three meals (i.e. breakfast, lunch and dinner) in comparison with placebo. This was seen in both the CGM profiles and the laboratory blood glucose measurements. Moreover, pramlintide compared to placebo treatmentsignificantly reduced time in hyperglycaemic range (≥180 mg/dL, 31 vs. 46%) and increased significantly time in target range (>70 to <180 mg/dL, 62 vs. 50%) while time in hypoglycaemic range was not significantly different between treatments (≤70 mg/dL, 7 vs. 4%). As it could be expected, subjects during pramlintide treatment suffered more from gastrointestinal adverse events than during placebo treatment (47% vs. 7%). Overall, the authors conclude that this approach of a fixed-dose administration markedly reduced post-prandial glucose excursions as well as glycaemic variability.
Although these results seem to be promising, it has to be kept in mind that this trial had a short duration and was performed under well-controlled conditions in a clinical setting with standardised meals. The potential of a fixed dose-ratio under real life conditions with varying meal portions and compositions needs to be evaluated thoroughly in future studies, in particular in the light of the potential hypoglycaemia risk with adjunctive pramlintide treatment, and its tolerability. Moreover, a co-formulation of insulin and pramlintide seems a requirement to advance this adjunctive treatment further for pump treatment. The use of two separate CSII systems is first not cost-effective and second would presumably not be accepted by patients.
In conclusion, current evidence of the effect of pramlintide as adjunct therapy for the treatment of T1D hints to a beneficial role of pramlintide, but future work is required to establish its role in routine clinical practice.


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Flaws of the Flawless System, or Blockchain Vulnerabilities
The excitement that has sprung up around the cryptocurrency and the blockchain topics has attracted not only supporters and critics of the new technology but also cybercriminals. After Bitcoin's exchange rate began to reach unimaginable levels of $20,000, attackers started looking for blockchain vulnerabilities. Most unfortunate for conscientious users is that they found flaws in cryptocurrencies in the elements related to their storage and transfer.
Attacks Associated with Blockchain
Crypto hackers never sleep. Day in and day out, they try to destroy the ideal concept of Satoshi, where it is said that Bitcoin is a decentralized system without control and regulation by the government, banks, and other societies that are associated with economics in the understanding of the participants of the system. And this is really so because Bitcoin and blockchain do not and cannot be responsible for the operations of crypto exchanges or improper storage of access keys to wallets where cryptocurrencies are located. This situation can be compared with the security of your front door. If you lock it up and lose the keys, and the thieves find them and rob your house, it will not mean that the house is bad, but that man is to blame. Therefore, all blockchain-related threats are associated with inattention, a frivolous approach to business, and an indifference to the details of crypto security.
It is necessary to know the sources and directions that the attackers might take to prevent hacker attacks on cryptocurrency investments.
Network Impact
A popular DDoS hacker attack is the Distributed Denial of Service that is conducted against a well-protected company. The cybercriminals operate according to the following algorithm:
They scan the network using prepared scenarios (for each case, an individual plan is developed) which identify potentially weak nodes;
The selected nodes are attacked, and the hacker becomes the system administrator of the network;
Trojan programs are installed on the captured nodes, which work in the background and require additional control;
Upon receiving certain commands from the hacker, the infected computers spread the virus to other computers that are in this network.
During a DDoS attack, the users do not suspect that their system is infected and pass data to the attackers, that is why this type of attack on crypto projects is one of the most infamous. In March 2018, for example, a network of second-tier payment channels of the Bitcoin blockchain Lightning Network was subjected to a DDoS attack. The organizer of the cyberattack was the anonymous BitPico group, which had a set of automated tools with the function of connecting to hundreds of nodes. The developers of the Lightning Network had not detected any vulnerabilities in the network then, but 200 nodes, or 20% of the network, were disabled.
Another known attack is the "Sybil Attack" that got its name in 2002 thanks to Microsoft Research specialist Brian Zill. He suggested renaming the pseudospoofing (the former name for the "Sybil Attack") in honor of the main heroine of the bestselling book of the 80s, where a girl named Sybil was treated for dissociative personality disorder. When afflicted by this condition, a person takes on several types of behavior and can behave like a woman, a man, a child, and others. "The Sybil Attack" can be compared with a mental illness because in this case the hacker assigns several identifiers to one node and thereby disrupts the entire network.
If we go into the details, there are no trusted nodes in peer to peer networks, such as on the Bitcoin and Ethereum networks, so each request is forwarded to several recipients. At the same time, users can have multiple identifiers from different nodes that can be used to share common resources. The received copies create redundancy, thus allowing to check the received data independent from a network.
But if you look at this approach from the other side, it turns out that all available nodes that must represent different recipients of the query are controlled by the same user. If the latter turns out to be a fraud, then the following transactions will be closed on node aliases.
This attack is gaining popularity because decentralized networks are growing, and with a large number of users, it is not advisable to require each network participant to confirm the ownership of their identifiers because it hinders the scalability of the network.
Another kind of attack at the network level is the Eclipse attack, or "The Eclipse Information Attack." This type of cyberattack was described in detail in the report of a group of scientists from the Boston and Jewish universities headed by Ethan Heilman in 2015. Their research described the causes of the first attack on the Bitcoin network, and an experiment conducted in the framework of scientific work demonstrates the vulnerability of the technology. Heilman later demonstrated the possibility of conducting an eclipse attack on the Ethereum network and proved that the entire system requires further development.
The Eclipse Information Attack allows the perpetrators to gain control over access to the node and its information. With proper manipulation in the peer to peer network, a hacker can "eclipse" the nodes so that they contact only the infected nodes.
In fact, this cyberattack is the first step in the organization of a "51% Attack." The information eclipse works as follows. The network contains three large mining nodes, two control nodes have 30% of the mining capacity (in the end, 60%), and the third node at 40% is responsible for the rest of the network. If a hacker owns a 40 percent node, then they can break 40 percent into two miners so that they cannot combine the blocks of each other. As a result, the blockchain of the attacker becomes a chain of the whole consensus block. After that, the attacker can manipulate the node and make sure that all its outbound connections are associated with the attacking IP addresses. To do this, they only need to populate the node's peer to peer tables with infected addresses, restart the current connections of all the users (this is often due to software updates and other issues), and create new connections for criminal IPs only.
Impacts at the User Level
The main and the simplest tools of the modern blockchain hacker are the botnets, which spread special anonymous malicious programs through droppers that masquerade as pirate versions of licensed programs. Considerable time and computing power are required for mining. To save resources, crypto hackers infect computers of other network users. As a result, these people yield considerable income to cybercriminals and do not even suspect about it. For example, a bot called Smominru for mining Monero infected more than half a million servers around the world for six months and yielded 8,900 XMR, or $2 million.
Vulnerability at the user level from a legal point of view is connected with de-anonymization of market participants. Since blockchain addresses are not tied to a person and all conducted transactions do not require the disclosure of participant identities in the transaction process, the crypto criminals use these advantages for their own nefarious purposes. If an attacker connects infected nodes to the network, it will be possible to trace the source of the transactions. In addition, the anonymity of the blockchain allows for transactions between terrorists and other criminals who engage in illegal activities.
Impacts at the Mining Level
The most popular threat at the level of mining is called the "51% Attack" that we wrote about in April of this year, when the network of the anonymous Verge cryptocurrency was compromised by a 51% attack. A few months ago, this attack occurred because of a bug in the code. On May 22, the attackers raided Verge again, and the problem affected all the pools and all the miners. Correct transactions were rejected as a result of the attack. Likely, the machinations were conducted between blocks 2,155,850 and 2,206,272, which allowed the attackers to steal 35 million XVG tokens, or $1.75 million in just a few hours.
Another impact at the level of mining is Double spending, which implies a double success of using the same funds. In principle, Bitcoin is protected from this vulnerability by verifying each transaction using the Proof of Work (PoW) consensus algorithm, and only after a minimum of three confirmations will the committed payment be added to the chain of blocks. In 2013, however, the Bitcoin system crashed as client program 0.7, which was installed by many users, stopped updating the records of the blocks. Version 0.8, which had been released a month before, continued to function in normal mode. The problem was that the next block under the number of 225,430 was confirmed by Bitcoin 0.8 customers, but not accepted by Bitcoin 0.7 clients. Thanks to this divergence, the miner made a double spend of coins in the amount of $10,000.
Selfish mining can be called the problem of the future. This is a strategy of Bitcoin mining, when users of the network are bound in special groups in order to increase their own incomes. This impact can centralize the network and kill the original concept of a decentralized system. The unification of mining capacities occurs in China, after all, this country extracts two-thirds of all Bitcoins in the world. If selfish mining does not stop, then all participants of the blockchain market will find themselves right where they started, that is, they will return a centralized economy in an altered electronic format.
Attacks Independent of Blockchain
There are methods of cyberattacks that can be applied to all technologies related to networks. These methods of fraud are not an intricate formula for stealing money. But the organizers of blockchain projects often forget about the banalest ways of hacking and become victims of criminals. To avoid this, it is important to remember the list of attacks that can harm the infrastructure, regardless of the use of blockchain.
Phishing is one of the most popular types of Internet fraud. It appeared in the 90s of the last century but is still popular. According to Group IB, in 2017 more than 50% of funds from blockchain projects were stolen by phishing. In the classic version, the attack is implemented through spam as mailings are sent on behalf of well-known companies with a request to confirm user data. People follow the links and thereby pass on their logins and passwords to the hackers.
But the attackers did not stop at copying accounts and began forging the websites of blockchain projects. In April 2018, hackers stole $150 million from the addresses of MyEtherWallet's cryptocurrency account by using phishing. The cybercriminals acted according to the following algorithm:
They registered a domain such as www.mye1herwa11et.com similar to the official website of www.myetherwallet.com;
Then they made a copy of the website's content and changed the address of the wallet;
They advertised the website on the internet;
Then they intercepted and redirected all the users of the real wallet to their own website.
The way to protect against phishing is pretty simple, as one has to carefully check all the characters in the domain name, visit websites through bookmarks, or each time copy links from a saved text document.
Defacing is a method of a targeted attack by using which the hackers attack the websites of blockchain projects and change the addresses used to raise funds for links to their own wallets. In July 2017, the Israeli startup CoinDash was defaced, and the project lost about 40,000 Ether in the first three minutes of the ICO, or more than $7 million at the exchange rate at the time.
Weak passwords make the hacking of blockchain project websites possible. To prevent an attack, one must use complex security keys and two-factor authentication.
A social vector attack involves stealing coins from the users of blockchain projects through social engineering methods. Just like in the case of phishing, the attackers pretend to be the employees of some company and convince users to share confidential information.
Other Vulnerabilities
The above mentioned are only a few of the vulnerabilities that are associated with the blockchain industry and human factors. The hackers can steal your passwords from crypto wallets, crack open crypto exchanges, and change the system time setting. Note that all attacks are associated with exposure at the user level, and not with the technology itself, which is protected from hacking and unauthorized actions.

redpajama_set_name: RedPajamaCommonCrawl


A Collector´s wine. A limited release Mencia highly acclaimed by Wine Advocate. 93 points Robert Parker. Gold Medal Decanter.
A 100% Mencia aged for 24 months in new French oak barrels. To be enjoyed now or over the next 10+ years.


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Argentina Part II : Cabernet Franc, Malbec, Sparkling in Search of Place and Purpose
by Anthony Gismondi, David Lawrason and Treve RingJuly 27, 2015
Over the past seven months, five of our WineAlign contributors travelled to Argentina, each bringing back different stories and aspects of the country. You can read Rhys Pender MW and Sara d'Amato's views in Part One of the series here.
A number of years ago I noted that when visiting Argentina, or most any other region for that matter, I was spending too much time in cars, eating lunch and dinner and not enough time tasting wines as they relate to the region, its terroir and its place in the world of wine. Hence the switch to early morning hotel tastings where themes and wines can collide and information is gathered in a much more efficient manner in a neutral space. Then the rest of the day, on the road, makes more sense.
A special thanks to the elegant Hyatt Hotel Mendoza for the room required and to Wines of Argentina for keeping an open mind and especially Edgardo del Popolo (Dominio del Plata) and Roberto de La Mota (Mendel Wines) for sharing some fabulous nuggets of information about their country, its wines and the places that make them special.
We wish we could see all these wines in Canada but the monopoly system and the general trend to taxing quality wine out of reach of the average wage earner in Canada makes it less and less likely. There are so many agendas that can foil the fine wine business in a heavily controlled liquor market like Canada. From ignorance to greed and back, the chances of seeing the brightest Argentina has to offer is left to a dwindling select few retailers and restaurants. Undaunted, our job is to uncover the latest and the best and push the names forward. The irony is, as the wine gets better and better, the quality, brought into Canada by many distributors, and sold by many retailers, government and private, is anything but. Certainly it does not reflect fast moving modern developments of a place like Argentina.
-AG
Cabernet Franc Ascending
By David Lawrason
I am going to state a bias upfront that Argentine malbecs pose difficulties more me. I understand them but I also find many to be blunt and monochromatic, especially at lower price points where young malbecs can have joyless rawness. I really do appreciate all the work underway in Argentina to fashion malbecs with more elegance, and I do score many very well. I also like the current movement to find more complexity and elegance by blending other varieties.
After two trips to Argentina since December I would argue that perhaps the best blender and alt-variety is cabernet franc. The first visit with WineAlign colleague Anthony Gismondi was a tightly focused, intense tasting foray, anchored by themed, comparative flights of wines at our hotel before we ventured into the fields of Mendoza and Cafayate. The second trip provided a much broader lens, accompanying a Gold Medal Plates group of Canadians to many of the same wineries, this time from a consumer perspective.
Globally, cabernet franc has long been used as a vehicle for bringing aromatic life and palate freshness to heavier wines. The negative can be that it thins too much and encroaches on ripe fruitiness with its herbal, tobacco leanings, even at moderate proportions. But the very ripe, full bodied reds of Mendoza are the perfect canvass on which to splash a little greenish franc-ness. The best show just a bit more elegance, freshness and complexity.
A caveat here that none of the wines I want to speak about are currently available in Canada – so not on the WineAlign database – but what else is new? Canada's liquor boards always lag years behind trends on the ground abroad. It is articles like this that might one day make them appear.
View from Bodega El Esteco
Among the handful of varietal labelled cabernet francs that scored 90 points or better I was most surprised and impressed by Kaiken 2013 Cabernet Franc, that would sell here for about $40. Sourced from a small block of "massal" or original vines in the Uco Valley, it presented very pretty, totally correct franc aromatics with excellent balance and length. Melipal 2013 Cabernet Franc from the Agrelo district of Mendoza showed classic currants, tobacco and great oak integration, a creamy palate then that tweak of cab franc greenness on the finish. Still in Mendoza, but from the very high altitude Guatallery sub-zone of Tupungato, Los Noques 2013 Cabernet Franc showed amazing lift, florality and freshness. And up north in Cafayate, Etchart 2013 Cabernet Franc showed lovely savoury cedar and tobacco and pink flowers. Very charming and less heavy than Mendoza peers.
As surprised as I was to find so many excellent 'solo' cab francs, I was just as intrigued to discover what cab franc does in blends. A little goes a long way. Staying up north in the province of Salta, Bodega El Esteco 2011 Altimus from the remote Valles Calchaquies carried only 14% cabernet franc and 25% cabernet sauvignon – a rich, quite oaky wine that really showed refreshing, dusty cab franc on the finish. Fuego Blanco 2012 from chalky soils in the Pedernal Valley of San Juan carries 10% cabernet franc co-fermented with malbec – lovely freshness, elegance, some minerality. The Pedernal Valley landscape is desert or semi-desert but at 1400 metres above sea level the temperatures are moderate with warm sunny days and cool nights. The rocky, poor-quality soils, glacial in origin, are dotted with flat, dark stones that give the valley its name, pedernal being the Spanish term for flint. Poor soils, low yields, it is a pattern.
Per Se 2012 La Craie from the Gualtallary region is a co-fermented gem with 65% malbec and 35% cabernet franc and another big winner from limestone (craie) soils. *See Anthony's in-depth look at this special wine below.
Manos Negras 2010 Atrevida is 97% malbec but the remainder is cabernet franc and it shows with just a touch of lift and franc tobacco. Perhaps this is all that is needed to keep Argentine malbecs aloft.
Whether the lead actor, or best grape in a supporting role, I came away convinced that cabernet franc's future in Argentina is assured.
Argentina's Cup Bubbles Over
by Treve Ring
When you think about Argentina, sparkling wine isn't top of mind, and possibly not even in the picture. That's poised to change, as vineyards climb ever higher and cooler, grapes are picked ever earlier and the diversity of styles more accepted than ever before. At the 2013 edition of the Argentina Wine Awards, the number of sparkling wine samples had increased by 220% over the 2007 edition, and a full 30% over 2012. In that year, this sparkling wine sector totaled $22,900,515, an 8.2% growth with respect to 2011.
Though espumante has been produced since the 19th century, it wasn't until the mid-20th century and the proliferation of pinot noir that bubble began to bubble upwards. Wineries both local and foreign started to show interest in the unique dry and sunny climate and unspoilt terroirs; Chandon, Mumm, Bianchi, Norton and Nieto Senetiner amongst the leaders in the sparkling stride. In the 1950's and after a worldwide search for new regions to develop, Moët & Chandon's oenologist, Renaud Poirier, named Mendoza the more suitable terrain for sparkling wine outside of France. Today, the Argentinian subsidiary of Moët & Chandon produces a wide variety of bubbles including Terrazas de los Andes and Baron B.
Refreshing with Norton with the Andes as a backdrop
Unquenchable global demand for Prosecco may have helped in recent years, with consumers wanting to branch out, safely, from a familiar charmat or tank style, not to mention a comfortable entry level price point which Argentina can hit. Though styles range from frothy and fruity to traditional method and serious, the majority that I saw in my travels there and on the shelves back home are akin to Prosecco, easy, approachable, fresh and accessible. Last year Moet Hennessy announced they will spend £1.5m in the UK to back the launch of Argentinian sparkling wines that it believes will tempt drinkers away from top-end Prosecco without asking them to pay Champagne prices.
The best examples, across all sparkling styles, come from altitude, allowing the grapes to take full advantage of relief from the intensity of Argentine sun. In the Uco Valley, and especially in the 1000m heights of Tupungato, chardonnay and pinot noir thrive, ripening easily while retaining crisp acidity when harvested early. In the high desert of Salta, and the arid otherworldly landscape of Patagonia, potential is great, and being recognized and utilized with greater reach every year. Malbec, sauvignon blanc, Chenin, torrontes, viognier and sémillon are also utilized, while pioneering producers trial other grapes.
Here are a few of my top sparkling picks from a brief visit to Argentina in earlier this year, as well as some that are available on our shelves in Canada. Salud.
Bodega Ruca Malen Brut NV, Uco Valley, Mendoza, Argentina
Bodegas Norton Cosecha Especial Brut Nature 2010, Mendoza, Argentina
Bodegas Escorihuela Gascon 1884 Extra Brut NV, Mendoza
Familia Zuccardi Cuvée Especial Blanc De Blancs NV, Tupungato, Mendoza, Argentina
Bodega Santa Julia Brut Rosé 2012, Mendoza, Argentina
From Calchaqui to Rio Negra. In Search of Place and Purpose
by Anthony Gismondi
David Lawrason and I had not travelled together in years but our recent visit to Argentina was certainly one of the best weeks we had spent on the road in ages.
Our first morning tasting (there were several) was hosted by two giants of the Argentine wine business: Edgardo Popolo, the general manager of Dominio de Plata and Roberta de la Mota, partner Mendel Wines.
We began with the oldest working winery in Argentina (1831) and one of the highest vineyards. Colomé Auténtico 2012 from the Calchaqui Valley in Salta is pure Malbec, from 90 year old vines made with little intervention. The vineyards are grown and worked using sustainable practices thus presenting the "authentic" expression of the terroir. The winery practices pigeage, does not use commercial yeasts or lactic bacteria to speed up the fermentation, acid correction and the use of sulphur dioxide is minimal and it has no oak influence. This begs the question why so many softer, sweeter versions of malbec make their way to Canada? If you are making under 100,000 cases we see no need for the fruit bomb malbecs that do little if anything for your image and frankly aren't all that healthy to drink.
One degree south takes us to Tolombón, where shallow, stony, splinter shale soils with quartz are the norm. The malbec here has a slightly riper, sweeter profile as seen in the Anko Flor Cardón 2012. It's classified Winkler IV, as was the Auténtico, but it seems a touch warmer likely due to the lower altitude. The fruit is sourced from the Estancia Los Cardónes district of Salta, the northernmost winemaking province of Argentina, located just south of the town of Cafayate at roughly 1700 meters along the eastern slopes of the Valle de Calchaquies. The little soil found there is packed full of crushed mica. Winemakers and co-owners Jeff Mausbach, Alejandro "Colo" Sejanovich and Saavedra Azcona and family have planted the rockiest sites looking for minerality. I know, I know the notion of minerality doesn't really exist in any wine… until you sense it. All I know is I'll take the stony minerality of this wine over a residual sugar, soaked brand any day.
High desert vineyards of Salta
Old vines are a big part of the story told by Viña 1924 De Angeles Gran 2012 Malbec. There are many old blocks offering different styles, weight and structure. The fruit here is 100 percent malbec and it comes off Parcel 3 at Vistalba, a site planted in 1924 at 980 metres. Density is a medium at 7,200 plants per hectare and the irrigation is old school by furrow. This wine never ceases to amaze from its big black licorice, black cherry, earthy, smoky nose to its savoury, intense palate awash in black cherries, smoked licorice root, tobacco, orange peel and vanilla flavours. A wonderful expression of old vine malbec made with just the right touch of modernity. The farming is organic and the fruit picked for the Gran Malbec is picked a week later than the regular.
Next up was the Viña Cobos Bramare Marchiori Vineyard Malbec 2012 that hails from Lujan de Cuyo, at Perdriel, (33°10'29.45″S). The site is at 980 metres above sea level and faces southeast presumably to escape the desert sun. The terroir is clay over sandy loam that gives way to gravel and stone. In fact the soils are alluvial and low in organic material but very well drained. The result is bigger, sweeter tannins with plenty of flavour. More Napa in style, it tends to jump the terroir and rely more on its dense sweet tannins, floral, black berry, tobacco aromas and intense black cherry and blueberry fruit with flecks of orange zest and violets. There's just enough minerality and acidity to keep it all interesting. Steak is a must.
A glimpse at two new wines from Gualtallary, Tupungato followed. This stony, high-altitude paradise lies just south of the city of Mendoza. First up was Bodega Aleanna Maldito Cabernet Franc 2012. At 13.8 percent alcohol this wine goes through a whole cluster co-fermentation with some malbec in cement before aging in 100-year old foudres. With no real wood influence other than it oxidative contribution the fruit is given a chance to shine. At 1400 metres the acidity is prominent at this stage and somewhat overbearing; it's a style but it's tart. According to La Mota and Popolo, Argentine cabernet franc needs time in the vineyard and time in the bottle.
Two kilometers away and some 100 metres below Maldito, Del Popolo makes 800 bottles of Per Se La Craie 2012, (translation by itself; and chalk). Some 1300 metres above sea level Per Se La Craie sits in the remarkable stone paradise of Tupungato. This elegant Gualtallary red, micro-fermented, tops out at 14.50% alcohol but you hardly notice it on the palate. In 2012 the grapes come from minuscule parcel selections originally planted for Dona Paula and in what was a warm year, Del Popolo chose all the limestone spots, in cooler vineyards to cope with the challenges of a warm growing season. The 65/35 malbec and cabernet franc is co-fermented; the wine spends 16 months in second use French barrels. Soils are amazingly complex: calcareous and alluvial gravels with the aforementioned spots of limestone. Both varieties were de-stemmed and they are fermented together with wild yeasts in French oak used barrels. Elegant and well-stitched Del Popolo credits talented winemaking partner David Bonami (Norton) for his assistance in year one. The fruit was destemmed before a 35 day maceration fermented on wild yeasts. The textures are chalky, silky and amazing. Bursting with fruit and minerality, it is a story teller. All class.
Vista Flores is the next stop heading south through the much heralded Uco Valley. Popolo's departure from Dona Paula was feisty winemaker Susana Balbo's gain. Upon his arrival at Dominio del Plata the first thing del Popolo asked Balbo was to consider taking her signature Nostros and set it free to travel to the best vineyard (fruit) each year. Originally the best vineyard in Agrelo it is now a Single Vineyard Nomade, a name meant to celebrate its journey every year to the best grapes they can find. Enter Dominio del Plata Nosotros 2012 Vista Flores, Uco Valley, Mendoza. In 2012 Nosotros is sourced from selected parcels in the region of Chacayes at 1200 metres, along the far west, high side of Vista Flores. The soils are complex, colluvial-alluvial origin with a sandy-loam frame in the first 10 inches. The second layer of calcareous soil and white gravels goes down two metres. Clearly more and more limestone sites are being planted to vine. More vertical and more linear, Popolo likes minerality and freshness while winemaker Susana Balbo likes sweetness and roundness with toast. So far it's a fine match; Nosotros 2012 is a delicious, intense juicy vibrant red wine made with intensity and balance. A star is born.
Familia Zuccardi Aluvional 2012 La Consulta, San Carlos, Mendoza was next and the level jumped another notch. At 15% alcohol you might expect it to assault you but after 12 months in concrete vats using indigenous yeast there is an electricity and freshness and fruit that is almost overwhelming. Aluvional is made from several sites, all handpicked by winemaker Sebastian Zuccardi in the La Consulta, San Carlos region. At 990 metres above sea level, some 130 km south of Mendoza City, this is the mother lode. The vines were planted in 1974 on poor alluvial soils of sandy-silt-clay mixed with rock. Love the tension and the acidity of what is a complex rich, powerful red, full of floral fruit. All hail Sebastien and his relentless fire to find the true home of malbec.
Next door to Zuccardi's Aluvional, the Mendel Finca Remota 2011 offers another look at Altamira, surely one of the finest pieces of terroir in all of Argentina. The 2011 was a little cooler than 2012 and the wine is a bit tighter. The vineyard is older, thought to be planted in 1950, the alcohol is a little lower at 14.3% and it spends 18 months in new French oak. Easily the most complex of the bunch, no doubt one of the most important characteristics of Mendel La Remota is the intensity and complexity of the fruit. Like the Angelus, it presents its old vines in the texture and viscosity that you don't get in younger vines. It presents as a polished river stone, not one you have just cracked open.
Another step south takes us to Doña Paula Los Indios Parcel 2012, a tiny sub-section of Altimira in San Carlos area of the Uco Valley. The fruit here is grown on sandy, silty colluvial soils with small brick-like stones in pink and orange scattered about. Yields are only four tons per hectare. Microvinification takes place in second-used 225 liters, French oak barrels filled with 170 kilograms (375 lb) of pure-clean berries. The barrels are closed up and sent to a temperature controlled room where the alcoholic, wild culture and malolactic fermentation takes place. To make a soft extraction, the barrels are rolled daily for 10 to 15 days. After that the wine is racked to new French oak barrels where it is aged for 18 months. This artisanal vinification method ensures that grapes are handled gently and all the process is carried out by gravity. Only exceptional years can spawn a Los Indios Parcel Malbec limited in quantity to 2000 bottles. Like the Aluvional the spice and violets dominate the nose with impressive acidity and or freshness followed by texture, texture, texture. Impressive to say the least at this young age.
We concluded the tasting with two 'southern' reds from Patagonia. First up was the Marcelo Miras 2012 Malbec from Ing. Huergo, General Roca, Río Negro planted in 1979. This was made in the traditional style and aged for 15 months in French and American oak barrels and from a typical north Patagonian desert climate – think warm days and cool nights at 39º 08´ S. Here you can get big colour and structure thank to the thickness of the skins so you must pay attention to prevent the wine from being to rustic. The growing season can be shorter, much like the south Okanagan Valley. Solid but in tough against the group.
The finale was Noemia de Patagonia A Lisa 2012 from Mainque, Valle Medio, Rio Negro, a 90/9/1 blend of malbec/merlot with a touch of petit verdot that are sourced from estate grown limestone and purchased from nearby vineyards, managed biodynamically. Again, freshness permeates this red with only 13.5 percent alcohol. Long days of light in the summer compensate for the wind and cool temperatures bring out the floral aspects to lift the mid-palate flavours. The tannins are soft here and almost sweet. Impressive already and yet only a baby; like all the wines in this tasting it needs time to reach its full potential.
A stunning morning that only reinforces how little we see from Argentina in Canada and how little we are likely to see if the gatekeepers continue to demand cabernet and chardonnay to fill a retail philosophy completely out of touch with the reality of modern wine.
As we wrapped up the tasting both del Popolo and La Mota reminded us, "We tried to show you our terroir. There wasn't any wine where our hope was to show you the grapes." Aclamaciones to that los caballeros. Your objectives were accomplished and more.
Argentina Part I : Rewarding Freshness
Argentina: Not Just a One Hit Wonder (VINTAGES Buyers' Guide)
Editors Note: You can find complete critic reviews by clicking on any of the highlighted wine names, bottle images or links. Paid subscribers to WineAlign see all critics reviews immediately. Non-paid members wait 60 days to see new reviews. Premium membership has its privileges; like first access to great wines!
Wine makes every meal an occasion, every table more elegant, every day more civilized.
Andre Simon


Tea with the fragrant flavour of bergamot and lemon.
Foil sealed for freshness. Great taste 2016. Our classic blend.Our classic blend In 1831 we created Earl Grey tea in our shop on the Strand on the request of the Prime Minister. He loved it so much he gave his name to it. Before long it had taken London by storm and it is still a firm favourite amongst people who like things with a twist, who travel off the beaten track and don't always play by the rules. What does it taste like? Our classic Earl Grey. A delicate tea with a delicious twist of citrusy bergamot. What makes this tea different? We carefully select a tea that is light, delicate and refreshing. It blends perfectly with the unique citrusy bergamot.
How do I drink it? Brew for two minutes. Three if you like a stronger cup. Add a splash of milk or simply drink it as it comes.


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import Units from './Units.js';
import { cosh } from '../math.js';
/**
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export var EXTENT = [-HALF_SIZE, -HALF_SIZE, HALF_SIZE, HALF_SIZE];
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Nikon today launched two new power-packed mirrorless cameras aimed at professionals as well as prosumers. With this leap into the full-frame mirrorless segment, the Japanese photography giant is also aiming to increase its share in the market and the Nikon Z7 comes with a new lineup of lenses create a new identity for the new mirrorless beasts.
Both the cameras have some appealing specs, however, the most attention-grabbing feature is the full-frame sensor which means the camera can capture exceptional detail in most lighting conditions. We were able to try out the Nikon Z7 at the launch event in New Delhi today and here are my initial thoughts about the camera.
Let me just remind you that these impressions are formed after only a few minutes of fidgeting with the camera, and I would be able to draw a better picture of its performance after being able to test it for longer.
The first thing that struck me about the Z7 is just how sturdy it is. The Nikon Z7 is definitely build to face harsh conditions and the weather-proof construction adds to that feeling. The Z7's body has a great grip and while it is bulky at more than 650g, holding the camera was not challenging or draining.
Most of the buttons comply with the standard Nikon DSLR design and you get a big rotating dial alongside the shutter button for better control compared to the standard donut-shaped dial. You also get two programmable buttons between the hand grip and the lens but this positioning of the buttons might not be very convenient as these buttons are prone to accidental nudges.
The touch-enabled monitor is very crisp and shows great colors and details, which makes the Nikon Z7 a desirable camera, even for the non-pros. The display can be tilted upwards and downwards but there's no way of tilting it sideways.
The left side of the body features stereo ports for headphones and mic inputs, as well as USB-C, HDMI micro, and another port for MC-DC2 shutter remote. On the right side, you'll find a port for the XQD memory card as the camera does not support SD cards.
On the top of the Nikon Z7, there's a small screen which informs you about the primary settings, so that you don't have to fidget for options on the display in the middle of a shoot. The electronic shutter button is clicky but it does not feel very tactile.
As usual, Nikon has done a decent job of maintaining colors close to the original. Besides professional photoshoots, Nikon is touting that the camera can be a useful tool for clicking pictures at Indian weddings and similar events of celebration. The full-frame design allows for a wider span of the frame. The touch screen along with its 493 focus points make it very easy to focus and shoot.
The menu is easy to navigate through, especially if you've handled a Nikon camera before. We used the standard 24-70mm lens with the camera and the shots were free from noise and ripe with details. So if you've been a Nikon user, you'll find it very easy to adapt to the controls and speed of the camera which, by the way, is commendable.
Comparatively, the Z6 has a sensor with a lower resolution and while the focus might not be as immaculate as the Z7, it does not lag behind when it comes to the speed of clicking shots or in terms of the reproduction of colors.
Nikon Z7 can be bought for Rs 2,69,950 for just the body while you'll have to pay Rs 3,14,950 if you plan to include the 24-70mm kit lens. The camera will be available at leading offline and online stores starting September 25. Meanwhile, the Z6 will cost you Rs 1,69,950 without the lens and Rs 2,14,950 with it but you'll have to wait until October to be able to buy one.


text:
Long Island Coronavirus Death Toll Tops 3,000
Healthcare workers wheel the bodies of deceased people from the Wyckoff Heights Medical Center during the outbreak of the coronavirus disease (COVID-19) in the Brooklyn borough of New York City, New York, U.S., April 4, 2020. REUTERS/Andrew Kelly/File Photo
At least 1,000 more Long Islanders died of coronavirus in two weeks, bringing the region's COVID-19 pandemic death toll to more than 3,000, New York State Department of Health data shows.
As of Sunday, Nassau County lost 1,770 residents to the virus and Suffolk County lost 1,256, according to the state data. Gov. Andrew Cuomo has said the state data only includes those who died in hosptials and nursing homes and doesn't include people who succumbed to the disease at home.
"Our thoughts and prayers to all of the families who have been affected by this virus," Suffolk County Executive Steve Bellone said. "We are thinking about you, we are you with you."
The death toll rose to 19,189 statewide, 67,686 nationwide, and 247,838 worldwide.
The rate of increase is slowing on Long Island, where fatailties had doubled from 1,000 to 2,000 in about a week in April. The latest milestone comes seven weeks after the first confirmed coronavirus fatality on LI was reported on March 16.
Minorities continued to make up a disproportionate amount of those lost in the Empire State. Thirty-four percent were Hispanic, 28 percent were black, 27 percent were white, and 7 percent were Asian.
The majority of those who died of coronavirus is still seniors. Eighty-four percent of New Yorkers who died of the disease were older than 60. The top three underlying medial conditions of coronavirus victims remains hypertension, diabetes, and hyperlipidemia.
As for overall confirmed coronavirus cases, the Island's tally increased Sunday to 71,635, with 36,780 in Nassau and 34,855 in Suffolk. That doesn't include nearly a half million Long Islanders believed to have contracted COVID-19 and recovered at home prior to getting tested, according to preliminary state study results. Long Island's first confirmed case was March 5 and its first suspected case was Feb. 7.
There were 316,415 confirmed cases statewide, 1.1 million nationwide, and 3.5 million worldwide.
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Related Story: LI Coronavirus Cases Appear To Be Declining From Plateau
Related Story: Nearly A Half Million Long Islanders May Have Had Coronavirus, Study Finds
Related Story: NY, Nassau, And Suffolk Launch Coronavirus Tracker Maps
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In 2005 organizers of international exhibitions "Bathroom & Kitchen" and "Interior World", present a new format of introducing the participants' products to their audience. Project "4 ROOM SHOW" is created to show the maximum opportunities of Your product to the broad audience of experts of the sphere.
In the frames of 2 exhibitions "Bathroom & Kitchen" and "Interior World" it is planned to create 4 hotel rooms of different levels (2, 3, 4 stars) and style. You can present one or more kinds of Your production for the decoration of the created interiors.
To participate in "4 ROOM SHOW" You just need to contact the Organizers & fill in an application form for this special project.
«4 ROOM SHOW» gives Your company an opportunity to carry out a PR-campaign of Your production the highest level in the hotel sphere, make Your brand recognizable in this segment of the market and make a prospective cooperation with the hotels of various categories.
A detailed description of each project containing the brands & used materials together with their providers will be placed at every ready interior & also at the web-sites of both exhibitions.
For today «4 ROOM SHOW» provokes great interest among the participants and guests of the exhibitions. All the 4 rooms are fully completed with the materials already and expect the beginning of the exhibitions.
You can find information about the participants and also the sketches of the rooms with bathrooms in the section of 4 ROOM SHOW "general information".
We will be glad too see You at our exhibitions.


B P Collins has been working alongside many High Wycombe based businesses and private individuals consistently during our 50+ year history. From our offices in nearby Gerrards Cross, we regularly act for individuals and businesses in High Wycombe, network and attend events in the town and have strong professional connections with many complimentary professional service businesses with High Wycombe headquarters or branches.
High Wycombe is local to many sizable businesses such as Biffa Waste Services Limited and we serve many of these businesses with employment law, commercial property law, dispute resolution and corporate and commercial advice to help them minimise risk, act as long-term advisors and advise on growth strategies.
The firm has supported waste management specialists and Wycombe based Biffa Group with corporate and commercial and environment law advice for many years since the 2010 merger with Greenstar, who we acted for since 2003 previously.
High Wycombe is extremely accessible with excellent transport links to assist local businesses. The M40 and connection to the M4 provides fast routes to London, Heathrow Airport, Reading and Oxford, meaning the town can attract many businesses from various sectors and inward investment from Europe and other parts of the world.
This is an area where B P Collins thrives by providing commercial business advice on setting up in the UK. This includes offering business immigration services from our employment law team by advising on skilled workers who need Tier 2 applications. We are also advising on the difficulties and challenges of Brexit.
The UK is currently working on a Brexit agreement to leave the EU bringing much uncertainty to businesses and individuals. One change which has been clarified is the new settled status immigration process for EU nationals. Our immigration team are here to help EU nationals living in High Wycombe with this new application process.
Wycombe employers should be advising their EU employees to keep up-to-date with the progress of implementation of settled status. Ultimately, this is the only route that will secure the status of EU citizens in the UK post 31 October 2019 and if EU citizens do not take these steps, there may come a point that they're regarded as illegal workers, attracting the significant penalties and sanctions that go with it.
High Wycombe attracts many commuters due to the Chiltern Railway train line connection from Birmingham to London. This means many staff and clients settle in the area and we often advise on residential property transactions (buying and selling), manage the wealth and estates of many generations of families with wills, trusts and probate matters and powers of attorney, as well as the breakdown of marriages with our empathetic family law team, who also advise on cohabitation matters, pre-nuptial agreements and civil partnerships.
Our dedicated employment law team has successfully represented many High Wycombe employees, workers, contractors and partners in Employment Tribunals for all types of claims, from disability discrimination and unfair dismissal to unlawful deduction of wages and breach of contract. They have also negotiated numerous settlement agreements for senior executives.
Our dispute resolution and property disputes teams have been helping many High Wycombe clients keep control of many personal disputes. They advise on the best approach, whether litigation or mediation, to advance and protect personal interests. With sensitive matters, such as inheritance disputes or slander, our specialist lawyers offer valuable support through difficult times.
We are able to offer a strong powers of attorney service to the High Wycombe community. Our private client solicitors can assist with your application to ensure your POA is executed efficiently and correctly. Our powers of attorney team deal with all issues with the upmost professionalism as we understand many cases can be stressful and difficult matters to address.
We have an exceptional rapport with families in High Wycombe. Our dedicated family law team understand the emotional demands and financial challenges that you will be facing whilst going through divorce and separation. They have successfully represented many High Wycombe families, guiding them through their matrimonial legal issues.
Our empathetic family law team will offer support through all marriage breakdowns and disagreements about the grounds for divorce. Our divorce solicitors offer support during these tough times.
Due to our proximity to High Wycombe, we are able to visit elderly private clients in the area. We have excellent relationships with local care homes who we visit to share our knowledge with their residents.
Our notary public service offering provides two notaries who can validate foreign documents for local individuals and businesses. This is a unique service, with many law firms unable to offer this service.
High Wycombe continues to regenerate and we advise property developers on new commercial and residential property usage in the area.
The firm has great connections to the main university in town, with a number of staff being graduates and alumni of the university or partner colleges (including the Oxford College of Marketing). We've regularly mentored student groups sharing our vast legal and business knowledge and given talks about what it takes to be a lawyer at careers fairs.
Many of our staff live in High Wycombe and the surrounding suburbs (including Hazlemere, Hughenden and Downley) and are active in the community. Many staff play at the Wycombe Heights and Hazlemere Golf Clubs. The firm has also had school governors at the Royal Grammar School in previous years.
Our corporate social responsibility programme is active in the town and over many years we've supported and sponsored many local events and organisations such Wycombe Wanderers Football Club, Wycombe Phoenix Harriers, Wycombe District Swimming Club and High Wycombe Law Tennis Club.


text:
FOXBORO -- Stephon Gilmore didn't love what he heard from Davante Adams earlier this week, when Adams said, "I don't feel like anyone can guard me right now."
Gilmore followed Adams around the field when the Patriots were in man-to-man coverage, allowing two catches on four targets for 15 yards. He also had a pass-breakup in coverage on Adams on a throw to the end zone from Aaron Rodgers.
"He was pretty good," Gilmore said. "But I play my game regardless of who I'm going against. I didn't like what he said earlier in the week. I kinda took it personal a little bit. But he's a good receiver."
Adams ended up with 40 total yards, but the majority of those -- including a two-yard touchdown -- came with the Patriots playing zone and Gilmore not the primary defensive back in coverage of Adams.
After dominating performances against Sammy Watkins, Allen Robinson and Kelvin Benjamin, for Gilmore to be able to limit Adams the way he did was arguably his most impressive performance of the season. Rodgers' No. 1 receiver was coming off of a three-game stretch in which he recorded 140, 132 and 133 yards receiving.
"I'm just trying to play my hardest," Gilmore said. "If they don't respect me, I'm trying to prove myself every game. That's what I try to do week in and week out."
Gilmore came into this week's game with a quarterback rating against of 55.7. He's now Pro Football Focus' highest-graded corner in terms of coverage, and their top-ranked corner overall.
I asked Gilmore if he felt as though this recent stretch is the best he's ever played.
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"Yeah. Week in and week out, yes," he said. "Just try to prepare. I have great teammates, safeties allow me to play aggressive, and coaches put me in position to make plays. So it's not just me."
The signature play from Gilmore's latest standout performance was probably his breakup in the end zone, which helped limit the Packers drive to a field goal.
After the snap, Gilmore ran into teammate Duron Harmon with three Packers receivers aligned on the defensive right side of the formation. Gilmore pushed through the contact to recover just in time -- he had to lay out -- to impact the throw.
"Had to get through," Gilmore said. "Sometimes when you get all those receivers together, you're running through so much you gotta fight yourself through to be able to make the play. It's a little make-up speed, and not giving up. Can't give up. Just gotta keep fighting to the end."
Click here to download the new MyTeams App by NBC Sports! Receive comprehensive coverage of your teams and stream the Celtics easily on your device.


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Larouco Hotels
Larouco Hotel Accommodation
Search 12 hotels in Larouco
See Larouco hotels on a map
Where to stay in Larouco
What's Larouco Like?
If you're looking to discover somewhere new, look no further than Larouco. Whether you're planning to stay for a night or for the week, the area around Larouco has accommodations to fit every need. Search for hotels in Larouco with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Larouco hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Larouco hotel deals are here with our lowest price guarantee.
Where are the Best Places to Stay in Larouco?
Below are the number of accommodations by star rating in Larouco and the surrounding area:
Things to See and Do in Larouco
Things to See near Larouco:
• Nuestra Senora de las Ermitas Sanctuary (4.5 mi/7.3 km from the city center)
• Montefurado Roman Tunnel (3.3 mi/5.3 km from the city center)


text:
Our Year-Round Programme
For Game Developers
Slush 2019 Outbound Mission
Our Hotel Partner
PARADE TERMS & CONDITIONS
A handy guide to what we're aiming for during London Games Festival
London Games Festival welcomes you to join in the UK's biggest ever gaming cosplay parade! This parade will be one of the festival highlights and a colourful costume celebration of video games!
To participate in the parade, you must complete the form on www.games.london/parade2019, and agree to read and abide by our Parade Terms & Conditions, laid out below. If you have any questions about the form or the parade, please email us at info@games.london.
We hope everyone has fun and remember to share all your parade pics with @LondonGamesFest on Twitter!
London Game Festival's first priority for our Parade is the welfare and safety of participants, guests, staff, volunteers, and security. London Games Festival staff, security teams, and volunteers for the Parade reserve the right to consider any costume, weapon or prop deemed to be unsafe or likely to cause a nuisance to be breaking these terms and conditions.
COSTUME POLICY
We are an inclusive festival (read about our Equal Opportunities Policy here). We kindly request that costumes worn during the parade have a PG rating so everyone can enjoy the day.
Regardless of your gender identification, we require all attendees, exhibitors and guests to please:
Select underwear that is modest and offers full coverage of your chest, groin, and bottom. (i.e. no bare boobs or bum cheeks) This extends to: No thongs, No singlets, No Vampirella-type costumes
A costume must provide this level of coverage at all times, including when standing, sitting, moving, or posing.
Coverage material must be thick and sturdily constructed with the proper undergarments (types of coverage that are prohibited include, but are not limited to, sheer materials, very thin materials, tape, pasties, body paint, liquid latex, and prosthetic genitalia).
Proper coverage must be held to the body by more than adhesives - that includes prosthetic glue, medical glue, theater glue, fashion glue and fashion tape. These adhesives may be used to assist in wearing the costume but cannot be the only method for keeping a costume in place.
The illusion of nudity is still nudity. Flesh colored garments must be easily identifiable from 10 feet away as garments, or they are deemed prohibited.
Please wear protective footwear at all times. This means some sort of hard sole (Flip flops, shoes, boots etc). Stocking feet are prohibited
Makeup must be properly sealed so that it does not rub off with casual contact. Please be mindful that body paint, glitter and /or fake blood are great fun for you, but other participants in the Parade might not want it on themselves.
It is YOUR responsibility to ensure that a Parade wristband / hand-stamp can be placed directly on your wrist / hand (not over costume or clothing).
The maximum dimension (height, width, or depth) of a costume is three metres. This excludes fabric trains and any parts that collapse to a smaller size, such as wings that fold down to within the size limits.
If a costume is bulky, made of hard materials, or includes parts outside of usual human dimensions, you must have at least one person with you as a guide.
Costumes, props, performances, and displays must not involve or create naked flames, explosions, nor arcs or bursts of exposed electricity.
Military dress
Costumes that may be considered military dress must not represent uniforms, emblems, or flags of organisations responsible for crimes against humanity
If you intend to wear a uniform that appears realistic, you must distinguish that it is a costume.
Costumes that could be mistaken for current military or law enforcement are prohibited.
Hateful symbols are prohibited.
Emblems of genocide are prohibited.
London Games Festival reserves the right to have the last word on the suitability of all costumes.
PROP POLICY
The London Game Festival appreciates that weapons and props are an integral part of gaming cosplay. But due to security we are prohibiting prop weapons of any kind at the Games Character Parade. We appreciate your understanding and co-operation in this matter.
City of London Police will be present throughout the event to help enforce this and will be confiscating any prop weapons at the Games Character Parade
Attendees bring items to an event at their own risk. London Games Festival Staff, security, or the Police may destroy confiscated items without warning.
ADDITIONAL TERMS & CONDITIONS
By participating in the London Games Festival Parade you agree to wear a wristbands / handstamps during the Parade to designate that a costume has been checked and approved by London Games Festival staff, security, and volunteers.
Please do not brandish props in a manner that could be interpreted as threatening or overly aggressive; be aware of how security personnel may interpret your actions during or in the surrounding area of the Parade.
Keep props on your person at all time. There will be no storage facilities for costumes, weapons or props provided for the Parade.
London Games Festival assumes no responsibility for damage incurred to your costume, weapons or props during the Parade.
Participants under the age 13 must be accompanied by an adult at all times during the Parade
By participating in the London Games Festival Parade you agree to the use of photography and acknowledge photos from the Parade will be used in future Games London marketing materials.
While Parade is a celebration at the culmination of the London Games Festival, it is also a showcase for your talents, passion and enthusiasm - and we respect that you're the star of the show.
The Parade will be well staffed with security teams and stewards - if you're unsure on the day, ask for help.
We will aim to provide as much pre-parade preparation space and support on the day as possible. These T&Cs are designed to lay the groundwork for that and create as fun an environment on the day as possible.
As well as our marketing materials, we will aim to produce a post-event pictorial magazine. Everyone participating in the parade will receive a copy from us.
Lastly: Top Tips!
Stay hydrated! Consider bringing a change of clothing if your costume is restrictive or if there is danger of overheating.
Be safe! The London Games Festival Parade will take place in central London. Please consider staying in a group, letting a relative or guardian know you are taking part, and plan your day in advance.
London Games Festival staff reserves the right to alter and update these terms & conditions to ensure a safe and successful Parade. London Games Festival reserves the right to withdraw access to the Parade or the right to ask you to leave if you are in violation of these rules. Compliance with the London Games Festival Parade Terms & Conditions is mandatory.
All make sense and want to sign up? Click here to go to the registration form.
© 2019 GAMES LONDON. ALL RIGHTS RESERVED.
THE LONDON GAMES FESTIVAL IS PART OF GAMES LONDON, AN INITIATIVE DELIVERED BY FILM LONDON AND UKIE AND FUNDED BY THE MAYOR OF LONDON.


i feel all right with the world.
we also watched a helluva flick entitled born into brothels. highly recommended times 100.
bean sends bb! one more reason to hate bloody wal-mart.
Actually, you can't blame Wal-Mart for that. The employee is the responsible party for contacting the police. It doesn't say that the employee was doing this under the guidance of Wal-Mart.


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Q: Combining wordpress themes Is there any way to combine two Wordpress themes without using a plug-in that renders pages in different themes, and if there is, what is the most efficient way to do so? Is it as simple as copying and pasting one theme's function.php (and other files) into the first theme? Do I make a child theme?
I'm trying to build a database for clean energy initiatives across the globe, and like the map functionality of one the themes I've purchased. However, once you go pass the map, the theme is not very user-friendly and cannot hold a lot of information. This is where the second theme comes in. I want to keep both the functionalities of both themes if possible.

A: If you are only using "a feature" of one theme, you may be better off taking your "standard" theme (the one you'd like to use throughout) and then taking the functionality from the "one-off" theme and adding it onto the former.
This goes in-part with the fundamental idea of not adding such functionality to a theme - it would be better suited for a plugin instead. That way, it's portable. Right now, you're facing a dilemma which could have been rectified by making that functionality portable.
I'd go back to the developer to ask them what's involved in making it into a plugin (it's not just going to be copy/paste).

redpajama_set_name: RedPajamaStackExchange


text:
package love.cq.util;

import java.lang.reflect.Array;
import java.util.Arrays;

import love.cq.domain.WoodInterface;

public class AnsjArrays {
	private static final int INSERTIONSORT_THRESHOLD = 7;

	/**
	 * 二分法查找.摘抄了jdk的东西..只不过把他的自动装箱功能给去掉了
	 *
	 * @param branches
	 * @param c
	 * @return
	 */
	public static int binarySearch(WoodInterface[] branches, char c) {
		int high = branches.length - 1;
		if (branches.length < 1) {
			return high;
		}
		int low = 0;
		while (low <= high) {
			int mid = (low + high) >>> 1;
			int cmp = branches[mid].compareTo(c);

			if (cmp < 0)
				low = mid + 1;
			else if (cmp > 0)
				high = mid - 1;
			else
				return mid; // key found
		}
		return -1; // key not found.
	}

	public static void main(String[] args) {

		int[] chars = { 1, 2, 3, 4, 5, 6, 8, 7 };
		chars = Arrays.copyOf(chars, 100);
		System.out.println(chars.length);
		for (int i = 0; i < chars.length; i++) {
			System.out.println(chars[i]);
		}
	}

	public static void sort(WoodInterface[] a) {
		WoodInterface[] aux = (WoodInterface[])a.clone();
        mergeSort(aux, a, 0, a.length, 0);
    }

	public static void sort(WoodInterface[] a, int fromIndex, int toIndex) {
		rangeCheck(a.length, fromIndex, toIndex);
		WoodInterface[] aux = copyOfRange(a, fromIndex, toIndex);
		mergeSort(aux, a, fromIndex, toIndex, -fromIndex);
	}

	private static void rangeCheck(int arrayLen, int fromIndex, int toIndex) {
		if (fromIndex > toIndex)
			throw new IllegalArgumentException("fromIndex(" + fromIndex
					+ ") > toIndex(" + toIndex + ")");
		if (fromIndex < 0)
			throw new ArrayIndexOutOfBoundsException(fromIndex);
		if (toIndex > arrayLen)
			throw new ArrayIndexOutOfBoundsException(toIndex);
	}

	private static void mergeSort(WoodInterface[] src, WoodInterface[] dest, int low,
			int high, int off) {
		int length = high - low;

		// Insertion sort on smallest arrays
		if (length < INSERTIONSORT_THRESHOLD) {
			for (int i = low; i < high; i++)
				for (int j = i; j > low
						&& (dest[j - 1]).compareTo(dest[j].getC()) > 0; j--)
					swap(dest, j, j - 1);
			return;
		}

		// Recursively sort halves of dest into src
		int destLow = low;
		int destHigh = high;
		low += off;
		high += off;
		int mid = (low + high) >>> 1;
		mergeSort(dest, src, low, mid, -off);
		mergeSort(dest, src, mid, high, -off);

		// If list is already sorted, just copy from src to dest. This is an
		// optimization that results in faster sorts for nearly ordered lists.
		if (src[mid - 1].compareTo(src[mid].getC()) <= 0) {
			System.arraycopy(src, low, dest, destLow, length);
			return;
		}

		// Merge sorted halves (now in src) into dest
		for (int i = destLow, p = low, q = mid; i < destHigh; i++) {
			if (q >= high || p < mid
					&&  src[p].compareTo(src[q].getC()) <= 0)
				dest[i] = src[p++];
			else
				dest[i] = src[q++];
		}
	}

	/**
	 * Swaps x[a] with x[b].
	 */
	private static void swap(WoodInterface[] x, int a, int b) {
		WoodInterface t = x[a];
		x[a] = x[b];
		x[b] = t;
	}

	public static <T> T[] copyOfRange(T[] original, int from, int to) {
		return copyOfRange(original, from, to, (Class<T[]>) original.getClass());
	}

	public static <T, U> T[] copyOfRange(U[] original, int from, int to,
			Class<? extends T[]> newType) {
		int newLength = to - from;
		if (newLength < 0)
			throw new IllegalArgumentException(from + " > " + to);
		T[] copy = ((Object) newType == (Object) Object[].class) ? (T[]) new Object[newLength]
				: (T[]) Array
						.newInstance(newType.getComponentType(), newLength);
		System.arraycopy(original, from, copy, 0, Math.min(original.length
				- from, newLength));
		return copy;
	}
}


text:
March 20, 2022 December 27, 2022 Tim Worthington
Looks Unfamiliar: Tim Worthington – Can I Have Some Gold Bullion And Pop Tarts Please?
This time Tim's the guest, joining Paul Abbott for a chat about California Fever, Galloping Galaxies!, inappropriately scheduled horror film Bad Ronald, the In-Flight Entertainment compilation series, The Chronicles Of Narmo by Caitlin Moran, Pirate Radio Four, The Collings And Herrin Podcast and Children's BBC music show What's That Noise?. Along the way we'll be finding out the correct manner in which to address multiple instances of Pete Waterman, meeting Robert Bloch's Pantomime Horse, revealing how Craig Charles facilitated the demolition of a school wall and catapulting all known copies of Let Us Now Praise Famous Men into the sun.
The Hoarding Extra – "Watch It Instead Of Ghostwatch"
Some additional Looks Unfamiliar chat as Tim Worthington joins Paul Abbott to talk about The Hoarding, a horror short written by, directed by and starring Karen Gillan that found itself getting a little bit lost at the height of lockdown. As well as taking a look at Karen's under-celebrated spooky and creepy film-making catalogue, there's also room for some thoughts on what makes a good horror film and why nobody might have wanted one while the world was at a virtual standstill, a look at the movies that sneaked out when cinemas briefly reopened and almost immediately closed again, and a brief impersonation of Paul Daniels…
Looks Unfamiliar The Hoarding Extra – Tim Worthington – Watch It Instead Of Ghostwatch – Looks Unfamiliar
If you've enjoyed this, you'll enjoy Tim's book Can't Help Thinking About Me, a collection of columns and features with a personal twist. Can't Help Thinking About Me is available in paperback here or from the Kindle Store here.
Alternately, if you're just feeling generous, you can buy me a coffee here. I mean I'm not expecting one direct from Rick's Place, but it would be nice.
You can find further appearances by Tim as the guest on Looks Unfamiliar talking about The Only Way by Lisa Stansfield, The Brain, the Jackanory adaptation of Starstormers, a Public Information Film about boat safety, I Was Made To Love Magic by Nick Drake, Secrets From The School Underground, Skyman and Rubovia here, Stop-Go!, It's A Shame by Kris Kross, Spider-Woman, I Wanted To See You To See If I Wanted You by Moose, The ITV Encyclopedia Of Adventure, The Young Poisoner's Handbook, the original version of Right Here by SWV and Radio Tip Top here, I Was Born On Christmas Day by Saint Etienne Featuring Tim Burgess, Ferrero Prestige, Bod's Present, A Merry Jingle by The Greedies, Doctor Who: The Christmas Invasion by Jenny T. Colgan, Mariah Carey's rendition of God Rest Ye Merry Gentleman, Richard Herring's Christmas Emergency Questions, Iron Man 3, Joe 90 Christmas Special The Unorthodox Shepherd and Merry Christmas Santa Claus (You're A Lovely Guy) by Max Headroom here, comedy on BBC Radio 3 here, Doctor Who: The Runaway Bride here and EastEnders spinoff single Something Outa Nothing by Letitia Dean And Paul J. Medford here.
You can also find Tim as the guest on his Marvel Cinematic Universe podcast It's Good, Except It Sucks talking about Guardians Of The Galaxy here, The Defenders here, Ant-Man And The Wasp here, Shang-Chi And The Legend Of The Ten Rings here and The Guardians Of The Galaxy Holiday Special here.
Paul has appeared as a guest on Looks Unfamiliar talking about The Compleat Beatles, Zeeb And The Martians, Crab E. Crab, Rock Lords: Narlies, the Commodore Plus/4 and The Late Night Funster Show here and the Christmas Special of The Peter Serafinowicz Show here, and on It's Good, Except It Sucks talking about Thor: The Dark World here and Iron Fist here.
You can read more about the story of my bizarre mid-afternoon viewing of Bad Ronald in You're Weird, Ronald here. There's also more about Rentasanta, the Christmas Special of Galloping Galaxies! ancestor Rentaghost, here, and further appreciation of Caitlin Moran's (and Andrew Collins' and Richard Herring's) literary works here.
Adrian Mole
Andrew Collins
Bad Ronald
California Fever
Colin Baker
Collings And Herrin
Craig Charles
Dig It! The Sound Of Phase 4 Stereo
Espresso Espresso
Further In-Flight Entertainment
Loungecore
Nicola Bryant
Pirate Radio Four
Slipback
Sue Townsend
The Chronicles Of Narmo
The Hoarding
The Karminsky Experience
What's That Noise?
Previous Looks Unfamiliar: Gabby Hutchinson Crouch – I Ate My Necklace, It Was Too Tasty
Next With These Pocket Coffee You Are Spoiling Us


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