Special Issue "Pathomechanisms of Atherosclerosis. Part I"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
With the recent globalisation of life style in many parts of the world, atheroscleosis has become a global disease with a significant health threat and economic burden, not only in the West, but now also Asia and Africa. Despite the well documented conventional risk factors for atherosclerosis, little is known about the major differences between geographical regions and whether the effect of those factors remains at a similar level of impact in all nations. This also raises the question about the exact pathomechanism of atherosclerosis and if it is uniform or may have different pathways between continents and countries. Furthermore, whether the pattern of gross pathology, e.g., thickened intima-media, plaque formation, calcification, etc., has become amenable to study and to accurately analyse, is not known; is it nation specific?
This Special Issue of IJMS searches for answers to some of the above-mentioned questions in an attempt to provide cardiology and vascular specialists with some answers that should lead to a better understanding of such a serious universal disease. We look forward to your contributions.
Angiotensin (Ang) II triggers vulnerable atherosclerotic plaque development. Bone marrow (BM)-derived cells are key players in atherogenesis but whether Ang II induces plaque vulnerability directly through Ang II type 1 receptor (AT1R) activation on these cells remains to be clarified. In the present [...] Read more.
Vaspin (visceral adipose tissue-derived serine protease inhibitor) was recently identified as a novel adipocytokine with insulin-sensitizing effects. Serum vaspin levels are reported either increased or decreased in patients with coronary artery disease. Our translational research was performed to evaluate the expression of vaspin [...] Read more.
Adropin, a peptide hormone expressed in liver and brain, is known to improve insulin resistance and endothelial dysfunction. Serum levels of adropin are negatively associated with the severity of coronary artery disease. However, it remains unknown whether adropin could modulate atherogenesis. We assessed [...] Read more.
Background: Coronary artery ectasia (CAE) is a rare disorder commonly associated with additional features of atherosclerosis. In the present study, we aimed to examine the systemic immune-inflammatory response that might associate CAE. Methods: Plasma samples were obtained from 16 patients with coronary artery [...] Read more.
Atherosclerosis is an inflammatory disease in which dysfunction of mitochondria play an important role, and disorders of lipid management intensify this process. Agmatine, an endogenous polyamine formed by decarboxylation of arginine, exerts a protective effect on mitochondria and modulates fatty acid metabolism. We [...] Read more.
Recent clinical studies have revealed the treatment of diabetic patients with sodium glucose co-transporter2 (SGLT2) inhibitors to reduce the incidence of cardiovascular events. Using nicotinamide and streptozotocin (NA/STZ) -treated ApoE KO mice, we investigated the effects of short-term (seven days) treatment with the [...] Read more.
Atherosclerosis, a chronic inflammatory disease that causes the most heart attacks and strokes in humans, is the leading cause of death in the developing world; its principal clinical manifestation is coronary artery disease. The development of atherosclerosis is attributed to the aging process [...] Read more.
Oral infections occur frequently in humans and often lead to chronic inflammations affecting the teeth (i.e., caries), the gingival tissues surrounding the teeth (i.e., gingivitis and endodontic lesions), and the tooth-supporting structures (i.e., periodontitis). At least four basic pathogenic mechanisms have been proposed [...] Read more.
High-density lipoprotein (HDL) particles have experienced a turbulent decade of falling from grace with widespread demotion from the most-sought-after therapeutic target to reverse cardiovascular disease (CVD), to mere biomarker status. HDL is slowly emerging from these dark times due to the HDL flux [...] Read more.
Patients with Chronic Inflammatory Rheumatic diseases (CIRD) are at increased risk of cardiovascular disease (CVD), ascribed not only to classical risk factors, but also to the presence of chronic systemic inflammatory response. Αtherosclerosis, the cornerstone of CVD, is known to be accelerated in [...] Read more.
Atherosclerosis (ATH) and coronary artery disease (CAD) are chronic inflammatory diseases with an important genetic background; they derive from the cumulative effect of multiple common risk alleles, most of which are located in genomic noncoding regions. These complex diseases behave as nonlinear dynamical [...] Read more.
Cardiovascular disease (CVD) is the number one cause of global mortality and atherosclerosis is the underlying cause of most CVD. However, the molecular mechanisms by which cardiovascular risk factors promote the development of atherosclerosis are not well understood. The development of new efficient [...] Read more.
Essential hypertension, fast heart rate, low heart rate variability, sympathetic nervous system dominance over parasympathetic, arterial stiffness, endothelial dysfunction and poor flow-mediated arterial dilatation are all associated with cardiovascular mortality and morbidity. This review of randomised controlled trials and other studies demonstrates that [...] Read more.
Tumor necrosis factor-stimulated gene-6 (TSG-6) is a 35-kDa glycoprotein that has been shown to exert anti-inflammatory effects in experimental models of arthritis, acute myocardial infarction, and acute cerebral infarction. Several lines of evidence have shed light on the pathophysiological roles of TSG-6 in [...] Read more.
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipids, smooth muscle cell proliferation, cell apoptosis, necrosis, fibrosis, and local inflammation. Immune and inflammatory responses have significant effects on every phase of atherosclerosis, and increasing evidence shows that immunity plays a [...] Read more.


"That was a great day yesterday at Braehead for all the 18 Virtual teams from around Scotland and for the 3 teams from Ayr.
Ok things didn't go so well as expected for one of the teams and it was very nearly good for another but the five member team of Mark Higgins, Andrew McElwee, Jack Shanks, Ann Nicol and Kay Bennett were unbeaten in the section games with two wins and a peel which took them to the semis of the low road which they won 4-0 but were then just beaten in the Final after a tough fight back.
And good to have the support of Alistair, Bob and Robert throughout the day.
A fitting end to a very successful year for the Ayr Disnae Virtual Club."
Thanks to Kirsty Letton for the above report.


Tuesday marks Farmers' Day, celebrated in Egypt on September 9 of every year.
Army general Abdel Fattah al-Sisi, who announced Mursi's ouster on July 3, 2013, has introduced what some described as austerity measures since he was elected president in June. In June, the government reduced energy subsidies and introduced new taxes.
Dank, a new youth movement recently launched to "achieve the goals of the January 25 revolution; supporting the poor and calling for decent living conditions for all Egyptians," is also among the rallying forces behind Tuesday's expected protests.
Movement members have denied to Aswat Masriya their affiliation with any political groups or factions.
A security source at the Suez Security Headquarters nevertheless told state-run news agency MENA that the Homeland Security was able to identify the masked men who appeared in the video. He reportedly said they belong to the Islamist Muslim Brotherhood organization.
Interior Ministry Spokesman Hany Abdel Latif told Turkish news agency Anadolu that security forces are ready to deal with any illegal activities that could be practiced by the Muslim Brotherhood or any other movement on Tuesday.
The Muslim Brotherhood and the anti-coup alliance have been holding protests on an almost weekly basis against the current regime since Mursi's military ouster in July 2013.


HILLSBORO, OR (KTRK) -- A memo sent to staff members at the Hillsboro School District in Hillsboro, Oregon has stirred a controversy over whether images of Santa Claus should be welcomed in schools.
Hillsboro School District spokeswoman Beth Graser told KATU as only sent to secondary principals as a reminder to be sensitive about the environments created in the school over the holiday season.
"It really went out as a notification to staff, not even parents, just to make sure they are being sensitive and thoughtful as they enter the holiday season," said Graser.
However, parents found out about the memo and complained, saying the school district had no right to sack Santa.
The school district blamed the backlash on local media coverage, saying the headline "Schools ban Santa" was misleading.
Graser added that there has been no policy change on the matter, and it was meant to ensure that a yearly door decorating contest didn't get out of hand.
"Quite honestly the 'competition' aspect meant that several of the decorations had gotten excessive," said Graser. "As a result, we had some staff members and visitors to our building indicate that they were uncomfortable and didn't feel welcome due to the overwhelming Christmas atmosphere that had been created."
She said public schools have a responsibility to ensure all students feel comfortable.
"We need to create inclusive and welcoming spaces for all of our students and realize that many of our students-because of their religion, culture, or other beliefs-do not feel comfortable (and in many cases may not be allowed by their parents) participating in activities that are holiday-based or religious in nature, or being surrounded by imagery that is a direct affront to them," she said.


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Work is well under way on creating the EFP's latest outreach project, which will focus on the links between periodontal disease and diabetes.
The periodontal world is grieving following the loss of one of its true giants, Steven Offenbacher, who passed away unexpectedly on August 9, 2018, at the young age of 67.
The Journal of Clinical Periodontology (JCP), the EFP's official scientific publication, has achieved its best-ever impact factor.


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Shrug and say, "Live goes on"
But it's raining on my soul"
Are we bored of the brain, or too thick to think?
Is there nothing left in this town?
Nothing to get my spirits high?
Now all I ask is what did you want from me?
And whisper Destiny's stopped screaming?
When did the party end?
By all the hollow lines you've spoken?


Created by accident and sustained by agricultural water privileges, the fate of Salton Sea in California may be sealed by the state's historic drought. If the lake isn't restored, it could spell ecological disaster for humans and wildlife alike.
Created by an accidental Colorado River canal breach in 1905, Salton Sea benefitted the area's rich farming culture, as agriculture in the Imperial Valley long received more water from the river than was proportional. The sea was sustained by (often toxic) farming run-off. The area became a tourist destination in the 1950s and 1960s, yet the situation became increasingly unsustainable.
Colorado River dependent states like Nevada and Arizona demanded more share of resources starting in the 1990s.
A Quantification Settlement Agreement was signed among several California water agencies regarding allocation of water from the Colorado River in 2003.
According to the 2003 deal, farmers in the state's Imperial Valley agreed to halt working on some 50,000 acres and to send that water to San Diego and Coachella Valley residents. The urban areas paid for water conservation efforts in the Imperial Valley, including lining canals and drip irrigation systems.
Salton Sea was given 32 billion gallons of water per year pursuant to the agreement since the lake had been sustained through agricultural runoff since it was created by the canal breach.
"That's a lot of water for a lake that not a whole lot of people like,"Michael Cohen, a senior research associate at the water-policy non-profit Pacific Institute,toldThe Washington Post.
This spring, California Governor Jerry Brown ordered a 25 percent cut in urban water usage based on ongoing drought conditions across the state. This contributed to the ongoing dispute as to whether large quantities of valuable water should be squandered on the lake.
Should the lake be preserved?
Since 2003, Imperial Irrigation District has put water directly into the 350-square-mile southern California lake -- the state's largest -- to stem its receding shoreline.
This week, Imperial County and the Imperial Irrigation District agreed to settle a 12-year dispute over restoration of Salton Sea. The conflict stems from the 2003 agreement and pledges made by the state and the various entities involved.
"This settlement agreement sends a clear message that Imperial Irrigation District and Imperial County are united in our efforts to advocate for a Salton Sea restoration plan," said Antonio Ortega, governmental affairs officer for the Imperial Irrigation District, according to Courthouse News.
The 2003 agreement is to end in 2017, leading many to worry about the environmental ramifications of allowing the lake to dry up amid a lack of water resources elsewhere.
"The state of California said in the water transfer agreement that they would restore the Salton Sea," Jessica Lovecchio, of the Imperial Irrigation District, recently told KNPR. "To date we haven't seen any progress with that."
The state's stalled restoration efforts have frustrated Salton Sea advocates.
"We're really pushing for a smaller, but sustainable Salton Sea," Lovecchio, with the Imperial Irrigation District, said. "We still want the Salton Sea here, we just want one that is manageable."
Two weeks ago, Gov. Brown proposed a task force focused on expediting conservation of the Salton Sea.
"Prior comprehensive plans to restore the sea are no longer feasible due to cost and decreased water availability resulting from the drought in California and in the southwestern states," the governor wrote.
Though locals have seen these kind of efforts before. They want concrete solutions from the state.
"Too many task forces and not enough action," local assemblyman Eduardo Garcia told the Desert Sun of the proposal.
The Salton Sea air basin's poor air quality exceeds the state's standards for wind-borne dust, according to KNPR. Should the lake dry up, high levels of arsenic, selenium, and traces of the long-banned pesticide DDT are lurking dangers.
Preventing dust spread would be expensive, yet a recent study by the Pacific Institute found that not addressing the problem would cost nearly $30 billion.
"If the sea dies, plumes of poison dust will whisk through the air at the speed of Santa Anas,"wrote Logan Jenkins of the San Diego Union-Tribune.
Imperial County already leads California in childhood asthma hospitalizations.
"I almost never go" to Salton Sea, nearby resident Maria Gudiño told KNPR. "But when I have gone, I have to cover my nose."
Gudiño said she and three of her children have asthma.
The lake, at 50 times saltier than the Pacific Ocean based on years of evaporation and stagnation, is home to only a handful of fish species that can survive such conditions. Salton Sea's shores are largely made of dried, ground-up fish bones.
Salton Sea, however, is a haven for birds: More than 400 species make the lake the second-most diverse collection of birds in the United States, according to The Washington Post. If the lake is not restored, experts say the bird populations will disappear.


text:
Donoghue, Winter make Orange Prize longlist
A pair of Canadians are among the 20 women on the 16th annual Orange Prize for Fiction longlist. Emma Donoghue (Room) and Kathleen Winter (Annabel) are both in contention for the book award, which recognizes "excellence, originality, and accessibility" in fiction written in English by women from around the world.
The shortlist will be announced April 12 and the winners revealed at a ceremony in London on June 8. The winner receives a prize of £30,000 and a bronze "Bessie" statuette created and donated by artist Grizel Niven.
By Natalie Samson
Category: Awards, Book news
Tagged with: Awards, Emma Donoghue, Kathleen Winter, Orange Prize for Fiction, women
Send feedback to Q&Q editors about this article

redpajama_set_name: RedPajamaCommonCrawl


text:
import numpy as np

import sharppy.sharptab.profile as profile

import urllib2
from datetime import datetime
import glob
import os
import imp

class abstract(object):
    def __init__(self, func):
        self._func = func

    def __call__(self, *args, **kwargs):
        raise NotImplementedError("Function or method '%s' is abstract.  Override it in a subclass!" % self._func.__name__)

# Comment this file

HOME_DIR = os.path.join(os.path.expanduser("~"), ".sharppy", "decoders")
_decoders = {}

def findDecoders():
    global _decoders

    built_ins = [ 'buf_decoder', 'spc_decoder', 'pecan_decoder' ]
    io = __import__('sharppy.io', globals(), locals(), built_ins, -1)

    for dec in built_ins:
        # Load build-in decoders
        print "Loading decoder '%s'." % dec
        dec_imp = getattr(io, dec)

        dec_name = dec_imp.__classname__
        fmt_name = dec_imp.__fmtname__

        _decoders[fmt_name] = getattr(dec_imp, dec_name)

    custom = glob.glob(os.path.join(HOME_DIR, '*.py'))

    for dec in custom:
        # Find and load custom decoders
        dec_mod_name = os.path.basename(dec)[:-3]
        print "Found custom decoder '%s'." % dec_mod_name
        dec_imp = imp.load_source(dec_mod_name, dec)

        dec_name = dec_imp.__classname__
        fmt_name = dec_imp.__fmtname__

        _decoders[fmt_name] = getattr(dec_imp, dec_name)

def getDecoder(dec_name):
    if _decoders == {}:
        findDecoders()

    return _decoders[dec_name]

class Decoder(object):
    def __init__(self, file_name):
        self._file_name = file_name
        self._prof_collection = self._parse()

    @abstract
    def _parse(self):
        pass

    def _downloadFile(self):
        # Try to open the file.  This is a dirty hack right now until
        # I can figure out a cleaner way to make sure the file (either local or URL)
        # gets opened.
        try:
            f = urllib2.urlopen(self._file_name)
        except (ValueError, IOError):
            try:
                f = open(self._file_name, 'r')
            except IOError:
                raise IOError("File '%s' cannot be found" % self._file_name)
        file_data = f.read()
#       f.close() # Apparently, this multiplies the time this function takes by anywhere from 2 to 6 ... ???
        return file_data

    def getProfiles(self, indexes=[0]):
        '''
            Returns a list of profile objects generated from the
            file that was read in.

            Parameters
            ----------
            prof_idxs : list (optional)
                A list of indices corresponding to the profiles to be returned.
                Default is [0]

        '''
        return self._prof_collection.subset(indexes)

    def getStnId(self):
        return self._prof_collection.getMeta('loc')

if __name__ == "__main__":
    print "Creating bufkit decoder ..."
    bd = BufDecoder()

redpajama_set_name: RedPajamaGithub


text:
Sensing Products debuted the Osprey small object radar at Security 2017, which this year returned to Sydney after a 3-year absence, and what a great show it was. Held over 3 days in the newly opened ICC at Darling Harbour, the exhibition hosted over 200 suppliers from the security industry. Nearly 5000 people from all over the APAC region travelled to Sydney to visit the show and of course many of those people stopped at our stand to see the latest unique innovation in perimeter protection.
As you will be aware Sensing is focused on the development of affordable, commercially available multi-function radar sensors, designed to detect objects previously undetectable by commercial radar solutions. The Osprey range of radar sensors are designed and manufactured by Sensing in Australia as part of a joint initiative with Corrective Services Industries.
Our stand showcased a small but exciting range of products that included;
The Osprey 9030, a short range, small object detection radar, that was primarily developed to detect contraband being thrown in to prisons and correctional services complexes.
The Osprey Air, which offers the same detection and discrimination as the Osprey 9030 but with extended detection range and enhanced UAV/Drone algorithms.
The Scan-360, a low cost, ground surveillance radar for perimeter security, with an operational range to detect humans and vehicles up to 200 metres, and to automatically operate a CCTV Pan Tilt Zoom (PTZ) camera to point at the intruder range.
Nexus, the command and control GUI, which provides and intuitive, map based user interface for networked Osprey radar sensors.
We also had the privilege of presenting a 15-minute introduction, with a Q&A session, to the Osprey 9030, to a small but captivated audience on the Thursday.
Throughout the show we received great interest in the detecting capabilities of the Ospreys, people were fascinated by the radars ability to detect objects as small as golf ball being thrown over prison perimeter fences. Everyone also seemed particularly impressed by the partnership we have with CSI (Correctional Services Industries) NSW which means that part of the manufacturing process of the Osprey units will be done by the prisoners themselves.
After such a successful show, we have already booked for next year's ASIAL Security Conference and Exhibition in Melbourne. We look forward to seeing you all again next year from the 25th to 27th July at the Melbourne Convention and Exhibition Centre.
For further information on our range of products please get in touch via our contacts page.
ICC Darling Harbour


text:
Why Oxford AstraZeneca's Coronavirus Vaccine Data Has Come Under Scrutiny
좋다?
추가한 사람 tum2wp 11월에 26, 2020
"Oxford University and AstraZeneca have acknowledged a manufacturing error meant some trial participants received only a partial dose of their experimental COVID-19 vaccine. The announcement has raised questions about why researchers did not mention the error when they claimed the jab was "highly effective" just days ago. It has also raised some concerns about the part of the study which showed a 90% success rate. Oxford and AstraZeneca have since addressed these issues and explained the next steps for the jab, to ensure its safety and effectiveness. Here is what we know: The study On Monday, Oxford and AstraZeneca announced preliminary results from trials showed an average efficacy of 70% – a figure reached by pooling the results from two different dosing regimens. One month apart, one set of volunteers received two identical doses while the other received a half-dose, and then a full dose. In the first group, the efficacy was 62%. In the second, 90%. The results were hailed a success, but it has since been revealed that some volunteers were only given a half dose because some of the vials did not have the right concentration of vaccine. Mene Pangalos, R&D lead at AstraZeneca, admitted to this dosing error to Reuters on Monday. The manufacturing error was only caught when some of the people in the study did not show the usual adverse effects. Oxford has said it discussed the problem with regulators and completed the late-stage trial with two groups. The second subgroup — the one that had a 90% efficacy — was also limited to participants aged 55 and below. In a statement on Wednesday, Oxford acknowledged a difference in manufacturing and measurement processes meant later phases of its clinical studies resulted in half a dose being administered instead of a full one. "The methods for measuring the concentration are now established and we can ensure that all batches of vaccine are now equivalent," it said. What this could mean ASSOCIATED PRESS U.K. Prime Minister Boris Johnson during a visit to the Jenner Institute in Oxford where he met scientists who are leading the vaccine research. Some parts of the scientific community have responded to the news with confusion and discontent, with Oxford and AstraZeneca coming under fire for lack of transparency. Experts have said the relatively small number of people in the low dose group — 2,741 compared to the 8,895 people who received two full doses — means it is difficult to know if that average efficacy is accurate. The fact that the low-dose group were all aged 55 and under has also sent alarm bells ringing. Younger people are generally at a lower risk of developing severe COVID-19, so the results of the group could merely reflect this stronger immune response. This is a particularly significant problem because many people on the list of groups to be prioritized to receive a COVID-19 vaccine in the U.K. would fall into the category of over the age of 55. Experts have also highlighted the fact that the results of the Oxford vaccine trials came out of two separate studies: one in the U.K. and one in Brazil. In the U.K., participants who were not given the vaccine were administered a meningococcal vaccine. In Brazil, the equivalent group was administered a saline placebo. The variation in "control" injections in volunteers has led to concerns that the data is not standardized and cannot be combined into a single efficacy result. Experts have said this error — as well as some other irregularities — have damaged confidence in the reliability of the results. "We just don't have all the information we need to tell whether these results are reliable," Natalie Dean, an assistant professor of biostatistics at the University of Florida, told the Financial Times. "We certainly don't have enough information in the public domain to decide whether this half dose is really working." Another point of confusion comes from a decision to pool the results to reach an average 70% effectiveness, said David Salisbury, an associate fellow of the global health program at the Chatham House think tank. "You've taken two studies for which different doses were used and come up with a composite that doesn't represent either of the doses," he told Associated Press. "I think many people are having trouble with that." By combining two separate trials into one combined data, Oxford/AstraZeneca could be indicating results from each were not clear enough to release on their own, Wired magazine reported, calling the incident a "scientific red flag with flashing lights." This could also mean the Oxford vaccine might not receive regulatory approval as soon as hoped. John LaMattina, a former president of Pfizer's global R&D unit, said it would be hard to believe regulators in the U.S. would issue an emergency-use authorization for the vaccine. Hard to believe that the FDA will issue an EUA for a vaccine whose optimal dose has only been given to 2,300 people. More data for this dosing regiment will be needed. https://t.co/WfxYkGNCXu— John LaMattina (@John_LaMattina) 십일월 24, 2020 What have Oxford and AstraZeneca said? A spokesperson from AstraZeneca said the trials were "conducted to the highest standards" and met their primary efficacy endpoint. Details of the trial results will be published in peer-reviewed journals and provided to U.K. regulators. These will provide a more complete picture of how effective the vaccine really is, and help regulators decide whether to authorize its distribution. When reached for comment, a spokesperson from Oxford University said: "During the phase III trials, our U.K. study used two dose levels. "The initial dose selection, which was agreed with regulators, was based on the same measurement of the concentration (using spectrophotometry) used in the phase I study, but, as a result of a difference in the manufacturing process for the later study, this method was subsequently shown to over-estimate the dose on the new batches of vaccine resulting in a half dose of the vaccine being administered as the first dose. "We have different ways of measuring the concentration of the vaccine and when it was apparent that a lower dose was used, we discussed this with the regulator, and agreed a plan to test both the lower dose/higher dose and higher dose/higher dose, allowing us to include both approaches in the phase III trial. "The methods for measuring the concentration are now established and we can ensure that all batches of vaccine are now equivalent." What about the other vaccines? The Moderna and Pfizer/BioNTech experimental vaccines only involved single trials and released trial protocols weeks ahead of time for expert scrutiny. But neither of the jabs has been tested for whether they break transmission of COVID-19, only for whether they stop people from developing Covid-19 symptoms or testing positive. Despite this recent news, the Oxford vaccine is still the best hope for many countries as it is cheaper than the mRNA vaccines and can be stored in a refrigerator instead of a freezer. It is also the UK's best chance for mass vaccination by the end of spring, as the government has already ordered 100 million doses to vaccinate 50 million people. A HuffPost Guide To Coronavirus Which airlines are blocking out middle seats for holiday travel? How does the coronavirus spread differently than the flu? Can you close your COVID "bubble" without losing friends forever? Is it safe to see grandparents over the holidays? How can you help a friend with anxiety when you're also struggling? Everyone deserves accurate information about COVID-19. Support journalism without a paywall — and keep it free for everyone — by becoming a HuffPost member today.
AstraZenecas, 코로나 바이러스, Oxford, Scrutiny, VaccineUnder
Staten Island Pub Owner Runs Into Deputy After Defying Coronavirus Restrictions
tum2wp	 1 년도 ~ 전에
["Michael M. Santiago via Getty Images The words \"Autonomous Zone\" are displayed at the entrance of Mac's Public House whose owner and manager are refusing to follow coronavirus restrictions implemented by New York ...
A New Coronavirus Relief Deal Is Finally Gaining Momentum In Congress
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Supreme Court Orders Review Of California's Coronavirus Restrictions For Churches
["워싱턴 (AP) — The Supreme Court on Thursday ordered a lower federal court to reexamine California restrictions on indoor religious services in areas hard hit by the coronavirus in light of the justices' recent r...
UK Approves Pfizer/BioNTech Coronavirus Vaccine For Emergency Use
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I really wish I had known about Shadi and Bahram Sadighian while I was writing my "Where Did You Get That?" article in this month's Washingtonian. Their Modern Rust line of furniture, which the couple builds from scrap wood is, as the name suggests, modern and rustic at the same time.
The line came about naturally, from the Sadighians' main company, Living Storage Quarters, which offers modern backyard sheds — another line I wish I had known about sooner.
Construction of these sheds left behind a certain amount of scrap and unusable wood, but Bahram didn't want it to go to waste.
"He would just bag them and bring them home — we had bags and bags of this stuff," Shadi says. "We just starting making things around the house that we couldn't find in stores." Little by little, of course, people started finding out and asking for pieces of their own.
"Because of the [reasonable] price point, it sort of hit a chord," Shadi says. And let's not forget the handmade element — that custom quality that people prize so much these days, especially in a tight economy, where they want to spend their money on things that are meaningful.
The work is just as meaningful to the Sadighians, who live and work in Alexandria. "It's a lot more gratifying than anything I've ever done before," Shadi says.
I'll close with the endearing portraits of Shadi and Bahram. I'm so excited to add one more name to my growing list of local furniture makers.
They just built a shed in my backyard. Excellent workmanship, very creative and just a great job all around.
I must say that I really do like that dining table – it offers a very rustic almost earthy style. I'm not too sure if the cream chair work with the whole setting.
Forget the table and chairs (although they are beautiful in their own rustic way) I want that shed by the pool! What a perfect "ladies getaway" that would make in my backyard. Oh to dream.


It's no secret that I love my hair! It's probably one of my favourite physical features about myself, so I absolutely adore pampering it! If you haven't seen any photos of me before, I have extremely long hair! Which means it's even more important to take extra care when washing and treating my hair. Longer hair can damage a lot easier than shorter hair!
I took the opportunity to try out the EcoStore Shampoo and Conditioner for normal hair! If you don't know a lot about EcoStore, they are an incredibly natural brand that originates from New Zealand, and have created a wonderful line of beauty and hair products, and even products for the home!
So, what did I think about the EcoStore Shampoo and Conditioner for normal hair?
"Plant-based shampoo with natural cleansing agents to gently cleanse and revive your hair without removing its natural protective oils."
It did make my hair feel a little knotted at first, but as soon as I worked through the conditioner everything was fine.
"Plant-based conditioner with sweet almond oil to add softness, shine and lustre to your hair."
I loved this conditioner! Like I said, the shampoo did make my hair feel a bit knotted (but hey, that's what shampoos always do!) but as soon as I ran this through my hair, it went ridiculously smooth very quickly! My hair was incredibly soft and shiny afterwards, and I adored the scent! It was a lot more subtle than the shampoo and had a hint of almond!
As you can see, it contains no nasty chemicals or ingredients! If you head to the web page, it actually explains exactly what each ingredient is!
As you can see, the mixture is very thin and you do not need a lot to work it through the hair. Even the bottle states that you will get the best results when just using a little. I found just using a small amount was definitely sufficient and didn't weigh my hair down!
Overall, I absolutely love this shampoo and conditioner combo! My hair felt amazing after using it just for the first time, and after prolonged use, I can really feel the difference! My hair is shinier and more soft. Any knots that do appear are much easier to work through! I would absolutely recommend this combo to anybody who is looking to make the switch to a more natural based shampoo and conditioner!
Check out the EcoStore website for more details on their brand, including their natural mission and their views on animal cruelty!
For direct information find it here for shampoo, and here for conditioner!
Have you tried EcoStore before? If so, what did you think?
Never tried ecostore before, but I'm a fan of natural shampoos and conditioners. Will put this on the list of things to try. Apparently they sell this just down the road from where I live! Score!
I love natural brands, I'm using Pro Naturals Moroccan argan oil shampoo and conditioner, they both work FAB, but I alternate with other shampoos and conditioners too. Thanks for the post!


Led panel passenger information display (LEDPIDSW) is a high-tech product designed for outdoor operation. It is designed to work smoothly in severe environmental conditions (rain, sun, storm and dust). Thanks to the specially designed plastic shades that are used in the led panels, it does not lose visibility even under direct sunlight. Panels can be produced in accordance with IP65 protection class when requested. In this case, the device is not affected by heavy rain and snow. When communicating uninterruptedly with the server over the 3G router, it consumes very little data. The LED modules used in the panel are 32x16 pixels in size and can be added vertically and horizontally side by side to increase the screen size if desired.
In order to contribute to the more convenient travel for disabled passengers, voice-over support for vehicles entering the stop and sound amplifiers are included in the device.
Apart from the 3G router option, the information boards which may be included in the Wifi networks in the squares or in the crowded areas are sometimes preferred by the local administrations. With the LEDPIDSW Wifi feature, it can join these networks and maintain contact from here.
Thanks to the daylight sensor, the control unit automatically adjusts the brightness of the LED according to the ambient lighting level. Thus, the brightness that disturb drivers at night is avoided.
The supply voltage is 220V AC and it is easy to install thanks to the ability to be supplied from the mains.


text:
Bakterien der Art Dolosigranulum pigrum sind grampositive Kokken, die in Paaren, Tetraden und Haufen gelagert sein können. Sie wurden 1993 erstmals von M. Aguirre beschrieben. Die Bedeutung des Gattungsnamens setzt sich aus drei Komponenten zusammen: dolosus - geschickt, granum - Korn, ulum - klein, der Artname bedeutet: pigrum - faul. Insgesamt bedeutet dies also geschicktes kleines faules Körnchen.

Stoffwechsel, Wachstum, Nachweis
Dolosigranulum pigrum ist die bisher einzige beschriebene Art der Gattung Dolosigranulum. Bakterien dieser Art wachsen gut auf bluthaltigen Festmedien und erinnern in ihrem Wachstum ("vergrünend") dort an Viridans-Streptokokken, anderen typischen Bewohnern der Nasen-Rachen-Raums. Verschiedene Stämme mit unterschiedlichen Sauerstoffbedürfnissen existieren. Hauptsächlich werden mikroaerophile und anaerob wachsende Stämme beschrieben. Was die Temperatur betrifft, liegt das Wachstumsoptimum bei 37° Celsius, ein klassischer mesophiler (=den mittleren Bereich liebender) Anspruch. Im Grampräparat können Bakterien der Art D. pigrum Ähnlichkeit mit Staphylokokken aufweisen, von diesen lassen sie sich aber mittels der Katalasereaktion unterscheiden, denn Dolosigranulum ist Katalase negativ. Mikrobiologisch identifiziert werden kann D. pigrum mittels 16s-rRNA-Sequenzierung oder Massenspektrometrie (MALDI-TOF).

Bedeutung als Krankheitserreger
Allgemein wird das Vorkommen von Bakterien dieser Art als benigne (gutartig) beschrieben. In seltenen Fällen werden jedoch zum Teil bedrohliche Infektionserkrankungen beschrieben, so wurde Dolosigranulum als unter anderem als möglicher Auslöser nosokomialer Pneumonien (im Krankenhaus erworbener Lungenentzündung), Blutstrominfektionen (Sepsis), Gelenkentzündungen und Keratitiden (Entzündungen der äußeren Haut des Augapfels) genannt.

Dolosigranulum, Staphylococcus, Streptococcus pneumoniae - Konkurrenzkampf
Dolosigranulum pigrum hat eine gewisse Publizität erreicht, da Bakterien dieser Art das Wachstum von Staphylococcus aureus negativ beeinflussen. Dies ist deshalb ein für die mikrobiologische und humanmedizinische Forschung so interessanter Fakt, da S. aureus zwar einerseits zur normalen Bakterienflora von Haut- und Schleimhäuten gehört und sich dort nicht bemerkbar macht, jedoch anderseits sehr ernste Erkrankungen hervorrufen kann. Hierzu zählen zum Beispiel verschiedene eitrige Entzündungen, aber auch Phlegmone oder Endocarditiden (bestimmte Formen von Herzentzündungen). S. aureus mit Methicillinresistenz (=MRSA) ist ein gefürchtetes, hygienerelevantes Bakterium, das allgemein schwieriger zu therapieren ist als ohne genannte Resistenzen. Darüber hinaus gibt es eine Vielzahl an unterschiedlichen Pathogenitätsfaktoren beziehungsweise genetischen Varianten wie PVL (Panthon-Valentin-Leukozidin), die zum Beispiel Abszessbildung und anderes mehr befördern. D. pigrum wird darum derzeit als potentiell sehr nützliches Bakterium aufgefasst, da das Vorkommen von Dolosigranulum mit der Abwesenheit von S. aureus vergesellschaftet zu sein scheint. Die gleiche Negativbeziehung scheint auch für Streptococcus pneumoniae (Pneumokokken - häufigster Auslöser bakterieller Lungenentzündungen) zu existieren. Der Theorie nach, und experimentelle Hinweise stützen das, konkurrieren alle drei Bakterienarten um ähnliche Nährstoffe, während sie ähnliche Regionen in und auf ihren Wirten besiedeln. D. pigrum, wenn in einem Makroorganismus (Gegenteil von Kleinstlebewesen) vorhanden, hat also entscheidenden Einfluss auf die Zusammensetzung einer lokalen bakteriellen Flora.

Behandlungsoptionen
Für die ausgesprochen seltenen Fälle von Infektionen mit Dolosigranulum pigrum gelten unter anderem Amoxicillin, Cefotaxim, Clindamycin, Levofloxacin und Meropenem als wirksame Antibiotika. Dies darf jedoch nicht darüber hinwegtäuschen, dass der Auslöser der Infektion nicht im Vorhandensein des Bakteriums liegt, da es normalerweise ein harmloser mithin nützlicher Kommensale im menschlichen Organismus ist. Einerseits sollten auch nützliche Bakterien nicht an Orte verschleppt werden, an denen sie normalerweise nicht zu finden sind (zum Beispiel Gelenke), andererseits ist in der Regel ein Vorschaden zu finden, wenn es zu einer Infektion kommt. So wurde beispielsweise für einen Fall mit einer Dolosigranulum-Pneumonie beschrieben, dass der betreffende Patient in der Kindheit eine Tuberkulose erlitten hatte, ein starker Raucher war und schon lange eine entsprechende Folgeerkrankung (COPD) hatte. Solange ein zugrundeliegendes Problem wie zum Beispiel eine Immunschwäche bestehen bleibt, ist ein theoretisch wirksames Antibiotikum unter Umständen keine wirksame Waffe. Darum sind betroffene Patienten häufig älter als 65 Jahre. Hiermit kontrastiert, dass Dolosigranulum zusammen mit Corynebakterien (die das Wachstum von D. pigrum begünstigen) selbst eine Art Therapeutikum zu sein scheinen. Es konnte für pädiatrische Asthma-Patienten gezeigt werden, dass deren Erkrankung sich dann verschlechterte, wenn Dolosigranulum durch andere Bakterien überwuchert worden war.

Einzelnachweise

Milchsäurebakterien

redpajama_set_name: RedPajamaWikipedia


Published as a series of letters in correspondence with a University of Cambridge professor, this work describes the native plants, animals, and people that William Smith observed during his time as Rector of St. John's Parish on Nevis, one of Britain's Leeward Islands. Interspersed in the letters about natural history are some discussing cryptography, a topic in which Smith seemed to have a great interest.
William Smith, Rector of St. John's, Nevis.
A Natural History of Nevis and the Rest of the English Leeward Charibee Islands in America: With Many Other Observations on Nature and Art…. Cambridge [England]: J. Bentham, Sold by W. Thurlbowrn, 1745.
A version of this text has been digitized and is available through the Internet Archive.
← -A Voyage to the Islands Madera, Barbados, Nieves, S. Christophers and Jamaica, with the Natural History of the Herbs and Trees, Four-Footed Beasts, Fishes, Birds, Insects, Reptiles, &c.
-Serious Reflections During the Life and Surprising Adventures of Robinson Crusoe: With his Vision of the Angelick World.
-A Voyage to the Islands Madera, Barbados, Nieves, S. Christophers and Jamaica, with the Natural History of the Herbs and Trees, Four-Footed Beasts, Fishes, Birds, Insects, Reptiles, &c.


text:
Joe Isuzu's Daily Slander
MYSTIC LAW OR COMMON SENSE?
March 3, 2008 Joe Isuzu 6 comments
We usually refer to Myo as "mystic" as in The Mystic Law. One explanation of the word "mystic" from an English dictionary describes it as this: a person who seeks by contemplation and self surrender to obtain unity with or absorption into the Deity or the absolute, or who believes in the spiritual apprehension of truths that are beyond the intellect. And the explanation of "mystical" is: transcending human understanding. Therefore, "mystic", by this definition, is the personification of that which is "mystical". So it would seem that when we Nichiren Buddhists refer to the "mystic law" we are referring to the personification of that which is transcendental to our understanding but is becoming integrated into our very person. But is that actually what we believe? When we refer to the "mystic" law we really think in terms of the "mystical" law, something that is apart from ourselves. And we don't think of ourselves as "mystics". Why is that? Is it because this law can only be understood between Buddhas and we don't think of ourselves as one? Perhaps.
Thomas Paine, author of Common Sense, wrote his pamphlet in response to the growing unrest in what was to become the United States of America, a term which he himself coined. In it he argued practical points of governorship; why be governed by those who are so removed by distance and by culture. But more importantly, he argued from a new philosophical paradigm; why be governed by one who has declared that his right to govern comes from an invisible metaphysical deity whose very existence requires a suspension of disbelief. Moreover, why even think of yourself as a subject to this man as you are also men and therefore his equal. This was radical thinking. Revolutionary thinking. Up until this time, every man, everywhere, had always been a subject to someone. And George Washington wasn't just the first elected president of the United Sates of America; he was the first elected president in the history of mankind.
But it takes a while for this type of thinking to actually become common sense. Common sense is an ever evolving condition, and as such, subject to change. But not always without some cost. In ancient Greece and through the Middle Ages, Ptolemy's geocentric model for the universe seemed to make perfect sense. It was the prevailing common sense based on the best empirical facts and observation for that time. So much so that the Roman Catholic Church incorporated it into its doctrine, imbuing it with a moral "a priori". This agenda made it very difficult to change common sense when new and improved set of observations presented a heliocentric model for how things worked. Even though a version of this model had existed in Vedic Sanskrit since the 7th century BCE, Copernicus published what were to become the quintessential bases of thought on the subject in 1543. But almost a hundred years later, the Church of Rome found Galileo guilty of heresy for following the position of Copernicus. And people of less stature than Galileo taking the same stance could easily find themselves burned to death as a heretic. So common sense doesn't necessarily mean that it's commonly used.
We who sit upon so many broad shoulders who came before us may at times forget how difficult it can be to work within a framework of time and try to advance new ideas for the benefit of our fellow humanity. I have often wondered why Daisaku Ikeda continually points to the works of Goethe, Kant, Spinosa, and Pascal, to name just a few pivotal personages of Judeo Christian thinking. What they have in common to some extent was the desire to clarify: to distill a thought so as to be better used by mankind. They all did what they could within the confines of society and government ruled by the Church. They all approached the process with a combination of scientific questioning and a religious imperative. They all asked the same three questions that are difficult to ponder; where did I come from, why am I here, and what happens after I die? They all reflected the same seeking mind as did Nichiren, revealing to Medieval Japan that it's subjects could free themselves from the bonds of birth, old age, sickness, and death. This is the same action that we who practice Nichiren's Buddhism take when we sit in front of our Gohonzon and contemplate our life. It's an act of courage.
So why do we think of the "mystical" law as such, and so separate from ourselves? It could be as simple as the words we use. Sam Harris, author of "The End Of Faith" states "To know what a given belief is about, I must know what my words mean; to know what my words mean, my beliefs must be generally consistent. There is no escaping from the fact that there is a tight relationship between the words we use, the type of thoughts we think, and what we can believe to be true about the world."
Myo in Chinese
"While I was thinking thus, a golden Buddha suddenly appeared in the hell of incessant suffering … As my agony subsided a little, I joined my hands together in prayer and asked him what kind of Buddha he was. The Buddha replied, I am the character myo…"
— Major Writings of Nichiren Daishonin, Vol. 4, p. 309
The word that is pronounced Myo by Nichiren Buddhists is composed of two Chinese root characters. The character to the right is Shao. The character to the left is Nu.
Nu by itself means "young girl," "thou," or "you." Shao is something small that has been cut in half — something fine, something difficult to perceive.
Kumarajiva used these symbols to express "wonderful," "excellent," "subtle," "fine," and "mysterious." It corresponds to the Sanskrit word Sad, meaning, "perfectly endowed" or "complete" round (Hokke) teaching (kyo).
Why is "mysterious" (mystic) a "young girl"? The answer lies in the nu character. The brush strokes that compose nu outline the image of the new moon. Look inside the brush strokes to see it.
The moon is at first a slender crescent that grows into full roundness, expressing the maturity of a young girl growing into a full (pregnant) woman.
The new moon is like a young girl. The full moon is a mature woman. The moon is by extension an expression of the cycle of birth and death, therefore "universal." The new moon only partially illuminates the full moon meaning "all has not been revealed" and is therefore "mysterious."
The moon illuminates the darkness as does hope (myo). Hope opens the doors that are "difficult to enter" in the Hoben Pon of the Lotus Sutra. The path illuminated by myo is medicine for all living things.
"Just as the moon is reflected in the water the moment it appears from behind the eastern mountains" (from the Major Writings, Vol. 3, p. 306), our world is illuminated by introducing all to Myo, the First Buddha of the Lotus Sutra.
http://www.gakkaionline.net/Imagery/Myo.html
Nichiren is constantly explaining Myo in terms of its relationship to Ho, as in that they are mutually co-dependent. Myo can be death, and Ho life. Myo contains the potential for life. Myo can be the potential for Buddhahood and Ho the manifestation of the other nine worlds which themselves contain Buddhahood, or Myo. Sad means perfectly endowed, wonderful, etc. So it is very hard to put into words something that is transcending of consciousness. So it would seem that there is a world of meaning in "myo" beyond our conception, or misconception, of the word "mystic". The deepening of our own self realization that we are indeed "myo" the Buddha, the more we take the "mystic" out of the Mystic Law and the easier it is for us to think of Buddhahood as common sense.
#1 | Written by Byrd in LA about 11 years ago.
Wow, Joe! Theres nothing I love more than a nice intellectual roller-coaster ride as a Monday morning wake-me-up!
I'm curious, though – I follow the M-Fing snakes thing (although the exact quote is "I am sick and tired of these M-F'ing snakes on this M-F'ing plane!"), but I don't get the Jude Law reference. Are we analogizing Jude Law to a young, pregnant woman? Or are we slyly referring to his propensity to impregnate young women? Are we purporting that his talent is waxing? Or round and full? Or ineffable? I fear I am far too linear a thinker for your blog, Joe. Please clarify.
Speaking of ineffable, I think what you may be getting at here with the "mystical" issue is the ineffable "numinous", yes? I thought so. Although the numinous is sort of luminous, whereas the mystic is merely ineffable. Everybody knows that.
I think some people are more prone to mysticism than others. I have a Nichiren Buddhist friend who is a total mystic, whereas I am much more of a political thinker. If you want to discuss governmental power structures, especially trans-Pacific ones, then I'm your gal. That's common sense.
Have a good week, and keep up the good work. Your pal, Byrd in LA
#2 | Written by Joe about 11 years ago.
The picture is just a joke; Mystic (pizza/Jude) Law.
The rest is an effort to start thinking in terms which do not create a duality between ourselves and The Law in an effort to take the "mystical" out of the equation. When we are told that our delusional self cannot understand something, it has a tendency to inhibit the heroic effort that it takes to transform ourselves into our authentic self, and thus see from a different perspective, that of Buddahood. It's heroic in that not only does it take Herculean effort, but the result is that what we now see cannot help but be effected our looking. We effect our environment with our life condition regardless if we are delusional or enlightened. Might as well be enlightened. But once accomplished or accomplished in an ongoing way daily, it not something to be thought of as unattainable any longer. It's not magic. It's common sense to live like this.
I didn't quote Sensei Jackson exactly because I was using him for my own purpose. But I'll keep more exacting quotes in mind for the future, mother fucker.
By the way, Rev Greg apologized for calling me a pussy. But it still stings, (sniffle). Because I am a pussy and I think he feels that is a bad thing to be. I may have to educate myself about pussy's and ninjas and do some commenting.
D'oh!!!!
I get it! "Mystic"! "Law"! It's like that moment in "The Miracle Worker" when Helen figures out that "wa-wa" is the word being spelled into her hand.
"Pussy" is sexist language. The politically correct term is nebbish.
Thanks for the thought-provoking piece.
#4 | Written by Rev. Greg about 11 years ago.
Warning Joe – don't try and educate yourself about Ninjas, we're mystical. And besides, if you learn too much, you may wake up dead.
Rev. Greg, Ninja
#5 | Written by gautam about 11 years ago.
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#6 | Written by wow gold about 11 years ago.
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I read this book months ago but wanted to give it the respect it deserved by waiting till my new site was up to share it.
It's one of the saddest stories I've read in a while. A love story that you hope and pray will survive the odds. It leaves its readers with the key message that life can be unfair and present you with obstacles you didn't deserve, but there is beauty and love to be found in overcoming them.
I'm reading one of the books I found in your site Ms. Cat. The one written by Rainbow Rowell, Eleanor and Park. Last week, I was also able to finish another book, Middlesex by Jeffrey Eugenides. I'm gonna be reading this next!
Oh, my heart. I love this book.
Thanks for stopping by! It wouldn't have been my usual book choice. I found it difficult to sympathize or relate to her protagonist during most of the chapters. I also had a hard time feeling the passage of time in her voice. But it was light enough to be an enjoyable distraction for a day or two. My favorite letter was the one she wrote her son before his first date. Looking forward to hearing what you thought of it!
I love this book… I've written the same quotes on my journal.
Have you read gone girl? or i think the best book i've read this year is the room, great book! or maybe that's just me because I'm a mother. Please check those books, if you still haven't.


Gerard is very active writing HTML5 games and has submitted some very good Firefox OS games to the Marketplace. He is a big proponent for the web, very active community member and a pleasure to work with.
I met Gerard through the Firefox Phones for Apps program that the tech evangelism team ran in 2013-2014. He's created a couple of well-rated mobile game apps for the platform and then became an active and responsive translator on our apps localization platform. I'm glad he's becoming more involved with technical evangelism and the MozCH community. Thanks Gerard!
Gerard is an active member of the Mozilla Switzerland community, regularly advocating the web, also through games he develops on Firefox OS.
Gerard is a MozillaCH community member who is very involved in Mozilla Switzerland. He also creates Firefox OS apps.


On to store for white wire italian lights (they were called back in the 80-90s). Four stores later, I give up and buy green *what? on a WHITE tree?? It's getting late and doggy has to go out by now.
Get home, string up lights - yech green wire...get the orniements unpacked and all over floor -- can't.find.hooks.
Am now using safety pins to hang them and it is beginning to hurt...alot.
I leave the tree as is for tomorrow to find white wire lights and hooks for ornaments.
It's a pleasant day. Almost warm. Dry. A little bit of sun. I feel GOOD--not needing gloves, scarf or even the BIG heavy coat - woohoo!
Third store: "Oh, you want the over the door hooks?" Me: "No, the hooks for ornaments to hang on the tree" Them: You mean the hooks you put in a china cabinet? Me: "No. The thin wire hooks to hang ornaments onto the Christmas tree".
Them: "Oh, I don't know if we ever had that kind. You could try string. Or pipe cleaners." Me: "hmm, k. bye. thanks"
Fifth store: "Try a Hallmark or a Dollar Store." Me: "where?"
*At this point, I am not even close to one of those above mentioned. Would mean a long trek back to Store One. It is now windy/sleet with freezy rain.
"Well, if we had them they'd be on the back wall." Me: "Oh, I looked and they aren't there."
SEVENTH STORE: "Yes, down the candy isle on the third shelf in a box.
Me: " I FOUND THEM!! THANK YOU!!" * I almost cried with sheer happiness.
Took 3-1/2 hours and half tank of gas, and maybe some frost bite. But it looks so much nicer with the white lights and NO safety pins holding the ornaments onto the tree.
Re: Fa - La - La - fa get about it La!
OMG, that could be a sitcom!
Merry Christmas. I'll bet the tree is beautiful!
LOL... Glad you found them! I'd offer a box of kleenix to dry your happy tears, but... I'm to late as usual.
Then I found GIDDIES! from a long time ago...ornaments of ice skaters. I found them to be so cute - which prompted a white tree for this year.
Love my themed trees! Since I no longer do holiday tablescapes -- this is what replaced that. jeesh I need a hobby.
My only "thing" is one ornament that is elusive: Pretty Giddie. She has a pink dress with green bows. There is one on ebay that is being sold along with one that I already have and don't want...but the seller is away.
I have checked everywhere. They do look cute on the tiny white tree and I found vintage shiny brites that match the colors of the skater ornaments.
Your tree sounds fabulous! I love looking at pretty trees.


Montana has a large diversity of different minerals that can be collected in the state. Western Montana is famous for having some of the only commercial sapphire mines in the United States. These mines produce beautiful sapphires of exceptional quality in a wide range of colors. There is also a considerable amount of gold that has been mined in Western Montana as well. The eastern side of the state is famous for some exceptional fossils.
Below are a few of mines that allow access by the public. Prices and access dates will vary, so be sure to contact each of these mines directly if you would like to learn more.
Since 2003 when the Blue Jewel Mine first opened its doors, there has been over 10,000 carats of beautiful stones sold to date! At Montana's famous Eldorado Bar, Blue Jewel Mine is a place where a perfect afternoon outing with a family can be well spent.
For a truly fulfilling outing expedition, panning the gravel for your own pieces of sapphire that are natural from the ground; no special form of treatment. You may be as surprised and excited as many other gemstone collectors who flock to this site in search of gemstones.
Crystal Park, a unique recreation area is located in southwest Montana is open for all your gemstone mining outings during the day. You can dig for the quartz crystals of all color varieties and the facility is universally accessible.
For car owners, there's a small access fee that goes into maintaining the site. Bring along your family for an exclusive rock hounding and fossil collection activities. For safety reasons, however, no one is allowed to access the abandoned mines within the facility.
This is Montana's largest and oldest sapphire mine. While there are many areas in Montana that are known for some of the finest sapphire stones, Gem Mountain Sapphire Mine is famous for creating beautiful stones out of the rough collected sapphire.
The site is expansive and you won't experience those often undesirable crowded sites. Buckets of gravel aren't costly and the gravel is already dug up and cleaned to make your entire search for the precious metals easy. A great activity for kids.
A free gold panning area has been set aside for recreational gold prospecting within the Kootenai National Forest at the Libby Creek Recreational Gold Panning Area. It is located 23 miles south of the town of Libby.
This area was the site of a short-lived gold rush during the 1860s. The areas was mined for several decades and eventually the area was both dredged and hydraulically mined as late as the mid-1940s. The area is now designated for recreational gold panning and is free access using basic tools. Contact the Kootenai National Forest for more information.
Spokane Bar Sapphire Mine in Montana is many sapphire lovers' haven, boasting lots of these beautiful gems. Every day, prospectors and adventurers flock the rugged terrains to find the precious stones that are collected from the gravel sourced from the best mines in Montana.
The rich gravels along the banks of Hauser Lake are some of the best sapphire discoveries in Montana. The largest sapphire discovered at Spokane Bar was 155 carats! On rare occasions, diamonds, rubies, topaz, and citrine specimens have also been found here.
Also Read: Gems & Mineral Map of the U.S.


Is anyone else having a crazy busy week? Between work, school, blogging, and attempting to keep up a social life, I have about zero free time. I am really hoping that things calm down a bit here soon. But until then, let's keep this short and sweet and focus on my Fall eats! Happy What I Ate Wednesday, friends!
Dinner a couple of times over the last week was a mushroom, tomato, and white bean stew that I served over cauliflower "rice." I'll have more on this in a future Friday Foodie Favorites post.
Has anyone tried these broccoli pancakes? If you haven't yet, you really need to. They sort of taste like a healthy version of hashbrown patties!
I served the broccoli pancakes alongside cut fresh green beans and leftover tempeh "bacon" (with BBQ sauce, of course!).
More tempeh "bacon" for breakfast. I'll have more on this sandwich coming soon!
Curry egg salad on rice cakes. It never ever gets old.
Sometimes you just need a little bit of vanilla almond butter right out of the jar.
An apple and sage vegan Field Roast sausage (these never get old) dipped in mustard with a baby baked potato and a side of broccoli. This was delish!
Annie's Cheddar Squares. These babies are so good!
Sometimes you just crave eggs. This recent breakfast was two pieces of toasted Ezekiel bread topped with two sunny-side up eggs and a side of cantaloupe. I am going to be SO sad when melon is no longer in season.
A new-to-me green Naked smoothie. This was the perfect substitution for my green smoothie when I was away from my Ninja (seriously, a tragedy).
There is no better way to end a post than with some chocolate. Toasted Ezekiel bread topped with peanut butter, cinnamon, and dark chocolate chips is seriously amazing. I love chocolate for breakfast! I healthified it a bit with a side of red grapes. The "Holiday" grapes are back and I could not be more excited about it!
Tell me… what have you been eating lately?
Haha, nothing wrong with that! You know I'm not judging!!
It is SO good!!!! I absolutely love it. The vanilla and maple flavors are my favorites.
Yeah it's a strange name... but they are delish! I bet Eleanor would like them too.
They are SO good! I seriously feel like I am eating hashbrowns.. but with broccoli added in!
Talk about a yummy food filled post!! Ive gotta look for those broccoli patties. Anything that tastes like hashbrowns is good in my book!
They are really good! I bet both you and Luke would enjoy them!
The Field Roast sausage sounds amazing! They don't sell it near me but I might be tempted to purchase a bulk order from amazon. Is it worth it? How do you make curry egg salad? Do you use Vegenaise?
I love the combo of chocolate, PB and cinnamon! it never gets old!
Never ever! It is the best!


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'In the Struggle' Series
2019 Blossom Bluff Retreat
The Reedley Peace Center meets in the Fellowship Hall of the First Mennonite Church, on 'L' street between 12th and 13th streets in Reedley, California (Directions).
Meetings are held most Friday evenings, beginning with a potluck at 6:30, and the program following (around 7:15 PM).
Misson Statement
The Reedley Peace Center provides a forum for those in our community striving for peace and social justice in our society. The Peace Center encourages individual and collective peacemaking efforts as a way to foster an atmosphere of hope, transformation, and reconciliation among all people, both locally and globally.
To attain this mission, we commit ourselves to the following:
We welcome people of all faiths, religions, creeds to join us in our search for peaceful solutions to local, national, and international conflicts and dilemmas
We believe that nonviolence is a viable and necessary response to the conflicts that occur at all levels of society, from personal to global
We will provide a community of hope and healing for all people looking for alternative solutions to conflict
Finally, we will encourage each other to have fun.
Most Friday evenings RPC meets at First Mennonite Church Fellowship Hall located on L Street between 12th and 13th streets (Directions). The meeting begins at 6:30 PM with a shared meal. The program begins at 7 PM. Programs feature speakers, videos, dramas, music, and more. Please refer to the Peace Center Calendar for details.
Students for Peace
RPC the Students for Peace club on the Reedley High School campus.
Victim Offender Reconciliation Program
(VORP) for cases in the Reedley area and at Reedley High School. See the Victim Offender Reconciliation Program of the Central Valley website for an introduction to the VORP program.
Local Native American concerns
Ballot issues / Propositions
Tax resistance / Peace Tax Fund
Valley air quality and water issues
Environment and Energy issues
Free Trade and/or Fair Trade
Gender and sexuality issues
Immigration and border issues
Racism / antiracism
Latin American issues
Interfaith understandings of peace
Small farms / family farmers
Media's role in a democracy
Intersection of science, religion, and culture
Description of Reedley Peace Center
Reedley Peace Center was conceived in the fall of 2002. It grew out of several book studies in a Sunday study group. Our reading and discussion clarified our thinking about the futility and evil of war, the tendency for structures to systemically favor the powerful, and consequently, to deal unjustly with the powerless and underrepresented. We were challenged to no longer be content just to study and discuss what we understood — we needed to find ways to more actively pursue paths toward peace and justice.
Prior to the invasion of Iraq, we undertook our first action by organizing candlelight walks down the main street of Reedley in opposition to the war. There were five of these walks in all. The largest drew 60 walkers. These walks always concluded with sharing and meditation in the city park across from municipal government offices. In conservative Reedley, there was much objection to our protest and antipathy toward our group.
When the war began, we stopped conducting peace walks, but continued prayerful meditation and sharing in the park. We began holding meetings at First Mennonite Church after these vigils. Programs originally consisted of watching informational videos and videotaped speeches by notable peace and justice workers. In early summer 2003 we stopped meeting in the park, but we have continued our meetings each Friday.
Friday evening meetings are usually informational presentations by speakers, but we have also watched numerous documentaries and have included a wide variety of programming. Each meeting is preceded by a shared meal.
Our speakers have helped us focus on peace and justice issues in many nations from the Middle East, the Far East, Latin America, and Sub-Sahara Africa. We have heard about the role of the US and of international organizations (IMF, World Bank, etc.) in causing and maintaining injustice in other nations. We have heard presentations that help us unravel the economics of peace and justice.
We have focused on environmental concerns, both local and global, and have learned of ways to live sustainably, both as consumers and as producers. This has brought increased attention on organic farming, buying locally, fair trade, and living simpler lives. We have had several 'Celebrations of the Small Family Farm.' We have also participated in recent anti-fracking climate rallies and marches.
We have learned about other local injustices suffered by immigrants, the homeless, local Indian tribes, farm workers, people of non-Christian faith, people of color, the LGBT community, and the poor.
We have studied politically divisive issues such as abortion rights, gay rights, the intelligent design/evolution debate.
One continuing thread in our programming is the theory and practice of nonviolence. A special event in this category was an intensive nonviolence training in the fall of 2010. The workshop, called 'From Violence to Wholeness,' was facilitated by Pace e Bene trainers. We have also heard the stories of many peacemakers and have had several speakers from Christian Peacemaker Teams, Pace e Bene, Fellowship of Reconciliation, Witness for Peace, etc. During the 2014-15 season we conducted a series of programs in which we studied and celebrated the many successes of nonviolent direct action throughout recent history.
In the fall of 2017 we held a second nonviolent action workshop led by Sarah Thompson of the Martin Luther King, Jr Center for Nonviolent Change. Most of this workshop was held at Fresno Pacific University to accommodate the greater Fresno area and university students.
Another intentional focus is Israel's Occupation of Palestine. Members from our group have participated in Christian Peacemaker Teams in Palestine. We have participated in the BDS (Boycott/ Divestment/ Sanctions) campaign to pressure Israel to a more just co-existence with Palestinians. In 2006 we hosted an exhibition honoring slain International Solidarity Movement worker, Rachel Corrie.
We have focused on the systemic injustice caused by economic policies that favor the rights of large corporations and financial institutions. We have studied the detrimental effects of these policies on the environment, worker's rights, international trade, etc.
We are also aware that working for peace and justice demands more than keeping informed. We attempt to find ways to help bring peace and justice to our community.
We have sponsored a Students for Peace club at Reedley High School. Students from this club have presented inspiring programs at the Peace Center. We support the peace and justice efforts of young people in every way we can. In 2010 we awarded $1000 scholarship to a college student who had shown particular courage standing up for gay rights on his campus. Beginning in 2014 we began awarding $200-$400 scholarships to senior graduates from Students for Peace. We sponsored the 2012-13 Students for Peace president as a participant in a youth leadership conference in Washington DC. This is a continuation of sending community members to conferences, both as participants and as presenters. Our collaboration with this student group continues to be one of the most rewarding parts of our history.
The Peace Center has worked with the Students for Peace Club members as they planned and implemented counter-recruiting campaigns on the high school campus. We have provided workshops on nonviolent action for the students who participated in these campaigns. In the fall of 2006, we sent a past president of Students for Peace and one of our own members to San Antonio, TX to participate and do a presentation at an interfaith conference on counter recruiting.
We have sponsored training in conflict resolution through VORP (Victim/Offender Reconciliation Program) and several in our group are VORP mediators. We have also served as mediators of conflict between students at Reedley High School.
We have worked with Reedley Police Department in an innovative restorative justice program called the Reedley Peace Building Initiative (RPBI). Most of the mediators in RPBI during the first two years were from Reedley Peace Center. The program is now in its seventh year and it has become one of the strengths of our community. It now has branches in the high schools and middle schools in our district and is being introduced in the Fresno Unified School District. Peace Center members and Students for Peace members continue to be part of this program.
From Spring 2007 through Spring 2008 we held a series of monthly public protests. These took place at the busy corner of Manning and Reed, under the Reedley College marquee. They focused on the escalation of the Iraq War and the growing threat of a military strike of Iran.
Many of our members took an active role in the protest of planned mountaintop mining of aggregate on Jesse Morrow Mountain (near Reedley) by a multinational corporation and of Carmelita mine by a local landowner. We have undertaken a letter writing campaign to stop this mine. In the summers of 2010 and 2011 we sponsored benefit concerts to support the Friends of Jesse Morrow Mountain. This campaign has now been successfully completed.
In 2004, members of our group facilitated interviews by a historical research team about local Japanese people who were sent to internment camps during World War II and of local residents who managed and maintained their property during the internment.
In the fall of 2008, we set up a week-long Hiroshima-Nagasaki Atomic Bomb Exhibit from the Hiroshima Peace Memorial Museum in downtown Reedley, and we have since presented this exhibit at several local schools.
In April 2011 we conducted a vigil/protest (in conjunction with US Uncut actions) at the local Bank of America to protest the failure of B of A and many large corporations to pay federal taxes. We believe that the relationship of government to large corporations is one of the underlying causes of economic injustice in our world.
In the winter of 2011-12, we held several 'bank walks', protesting at Bank of America, Chase, Citibank, and Wells Fargo, in solidarity with the Occupy movement. In 2013 we hosted a legal assistance workshop for homeowners and renters caught in foreclosure actions.
We hold an annual retreat. Twice this retreat was at Independence on the east side of the Sierra, and thirteen times at the St. Nicholas Retreat grounds in the nearby foothills. In recent retreats, Students for Peace members have attended and have been featured as part of the program.
The 2018 retreat focused on capitalism and its role in inequality and injustice in society. The Ilan Ziv six part documentary, Capitlaism, was the backbone of this study and discussion was facilitated by Andrew Fiala, philosophy professor at CSUFresno.
In the fall of 2014, we planned and carried out a project as part of Pace e Bene's 'Campaign Nonviolence.' The goal was to expose community members to past successful nonviolent direct action campaigns in the 20th and 21st centuries. Reedley High's current and past Students for Peace members were part of both the planning and the action of this campaign. This is an ongoing project for Reedley Peace Center.
In 2014 we became an affiliate of The Fellowship of Reconciliation.
In the fall of 2016 we hosted a series of eleven programs called 'In the Struggle.' 'In the Struggle' is a history of academic scholarship and community engagement in the San Joaquin Valley. This series examined the democratic purposes and civic values of scholars who conducted research and advocated for change as the region's rural agricultural economy consolidated and industrialized. It related the narrative of the activism of these scholars as they lobbied to enforce existing federal laws, organized underserved communities, led labor strikes, founded community development programs, created non-profit institutions in addition to working as traditional social scientists.
In January 2017 we sponsored a bus to the Women's March in Los Angeles. We continue to be distressed with the direction this nation is taking and seek ways to resist. Several members have become involved in trying to bring about political change. Students for Peace has conducted a voter registration drive on the high school campus.
Many in our group have served terms in other countries with Mennonite Central Committee (as material aid workers and as teachers) and many volunteer large amounts of time in local MCC programs such as the local World Handcrafts store and the Nearly New shop. Several have volunteered with Christian Peacemaker Teams, Borderland solidarity walks, Witness for Peace, and Alternatives to Violence. Some have worked with Mennonite Disaster Service, rebuilding homes and restoring damaged property. Several have served with the Peace Corps.
© 2022 Reedley Peace Center


« Islamic Law to Be Implemented in Egypt, then on to Jerusalem?
According to Archbishop Usher's chronology, Adam and Eve were created in 4,004 B.C. Adam and Eve disobeyed God (sinned and cut themselves off from God) in the Garden of Eden exactly seven years after they were created according to the book of Jubilees which would be year 3,997 B.C.
"Is God Adding 15 Years Till the Coming of the Messiah?" . Counting from Creation in 4,004 B.C., the year 2012 is fifteen years from 1997. Is this then, a year of transition, beginning the transition to the end of this age and the world of tomorrow?
If the Isaiah 38 prophecy about Hezekiah's added fifteen years refers is based on the 6,000 year period which started from the year of Adam and Eve's transgression in 3997 B.C., then 15 years added to 2004 A.D. would bring us to 2019 A.D. – exactly seven years from now!
With these things in mind, it is very interesting to me that the Mayan calendar does say that the calendar of time ends on December 21, 2012 which is the winter solstice this very year.
Basically, William Dankenbring has tended in the past to rely on the incorrect calculations of James Ussher (normally spelling is not Usher) to determine when the 6,000 years ends (for details about Ussher's errors, see Does God Have a 6,000 Year Plan? What Year Does the 6,000 Years End?). Since the end did not come 6,000 years after Ussher's date, William Dankenbring at first essentially declared we were living in overtime. Now he claims because God granted Hezekiah 15 additional years, that God's 6,000 plan for humankind to rule itself is 6015 years. Plus he believes that the Great Tribulation should start around the end of 2012–it cannot and will not.
William Dankenbring was once a writer for the old Worldwide Church of God. His tendency towards inaccurate and outrageous speculations distanced him from that church and he has been on his own for some time continuing to make inaccurate speculations. Of course, he has had some many start of the Great Tribulation and return of Jesus dates, that he may accidentally get it right once.
Although he, James Malm (an independent whose inaccurate prophetic speculative dates have also proven wrong), and others suggest otherwise the Great Tribulation will not begin this year. It will not begin prior to 2015 and most likely later than that.
Enough of the scriptural signs are simply not there yet. As far as some specific signs, for one the Europeans are not ready for their King of the North role yet and it is not possible that they will be any time next year either. Matthew 24:14 has still not been fulfilled completely (related to gospel proclamation) and the end cannot come until it has been. We have also not seen the type of wars, famines, and pestilences that Jesus described in Matthew 24:4-8 yet–and those need to happen more PRIOR to the start of the Great Tribulation. Nor have we seen a deal (apparently a peace deal) related to the one in Daniel 9:27.
People need to search the scriptures (cf. Acts 17:11), for if they do, they will realize that there is no possibility that the Great Tribulation can begin in 2012. Nor did God add 15 years to the 6,000 years as William Dankenbring is currently suggesting.
Perhaps he, James Malm, and others should read and study my book 2012 and the Rise of the Secret Sect. Not only does it have a detailed chronology on the 6,000, thus far world events have aligned with at least 22 biblically-based predictions in it–and it also teaches that the Great Tribulation will not start nor will the world end in 2012. And it will be right about that.
Teachings of Triumph Prophetic Ministries William Dankenbring's ministry–incorrectly speculates on various dates and holds to some odd doctrines.
Error-Ridden James Malm Not Doing an Elijah Work James Malm is an 'independent' who misunderstands and often improperly maligns.
Can the Great Tribulation Begin in 2012, 2013, or 2014? Can the Great Tribulation begin today? What happens before in the "beginning of sorrows"? What happens in the Great Tribulation and the Day of the Lord? When is the earliest that the Great Tribulation can begin? What is the Day of the Lord?
2012 and the Rise of the Secret Sect This is a link related to a book by Bob Thiel (COGwriter). This link also has YouTube videos. This book documents and explains hundreds of prophecies. And since it was published, world events have aligned with at least 21 predictions in the book and many more will to come to pass. Those who purchase the book at the www.thesecretsect.com website receive a lengthy bonus report documenting world events that aligned with the book.
2012 e o Surgimento da Seita Secreta (Portuguese Edition) 2012 livro do Dr. Thiel em português. Este livro documenta e explica centenas de profecias. E desde que foi publicado pela primeira vez, pelo menos 21 já começaram a acontecer.
2012 e o Surgimento da Seita Secreta (Brazilian Portuguese Edition) 2012 livro do Dr. Thiel. Edição em português do Brasil. Este livro documenta e explica centenas de profecias. E desde que foi publicado pela primeira vez, pelo menos 21 já começaram a acontecer.
This entry was posted on Wednesday, May 9th, 2012 at 6:24 am	and is filed under COG News, Prophecy.
Ariel Sharon died. His death is disproves at least one TPM hypothesis.


text:
Manic, Godless Teens on 15th Modulation of "Tomorrow"
by Annette Storckman. @astorcks.
LOGANSPORT, Ind - A gruesome scene unfolded in the early afternoon today at Central High School as a roving gang of manic teens hit an unprecedented, downright dangerous fifteenth modulation in "Tomorrow" from Annie, horrified sources confirmed.
"This is some pretty normal show choir nonsense," says Mrs. MacAfee, the school's choral teacher and the first person to report the event. "When I heard the first key change in 'Tomorrow,' I thought nothing of it. That song has been stuck in my head for 20 years, and sometimes it's nice to hear it out loud instead of just a pulsating refrain that keeps me awake at night, whispering dark secrets of the Elder Thing. As far as I know, that song has about three modulations. But when I heard the sixth, I knew we were in trouble."
Students in the room say the sixth key change was a dare by soprano, Lila Jenkins, as she screamed cursed orders at the class accompanist.
"Keep going Adam, you coward! I can hit it," yelped Jenkins as she began to drool black sludge. "We all can! No one can stop us, no one can stop Show Choir, not even God!"
By the ninth in-tune key change, the teens, crazed with their new power, began to roam the halls, summoning rivers of blood and continuing their key changes. The tenth modulation was so powerful, two teachers completely lost their eyesight, and on the eleventh, freshman Patricia Meyers was turned into an actual Depression-era mop.
"Don't you understand? The cruelty is the point. THE CRUELTY IS THE POINT!" noted Meyers, who, again, is now a mop. "Can anyone stop them? Can anyone bring this frenzy to a halt? Or better yet, once we witness their true power, will anyone even want to?"
At press time, S.W.A.T. teams, The National Guard, and a select fleet of older rich men who must learn to balance work life with what they're really passionate about have been dispatched to the school for defense. The government is yet to dispatch any shaggy dogs which is, at this point, beyond even this reporter.


The Election Commission Of India is working towards easing Candidates procedure for filing nomination and permission during the election period. The nomination and permission is filed through web application namely SUVIDHA. To make it accessible for the candidate to check the status and updates of his application we have created Candidate Mobile App.
This app allows candidates to check the status of their nominations and permissions filed via SUVIDHA.
Nomination: Candidate can view the status of his nomination. The candidate has an option to view the affidavit and receipt.
Permission: Here a candidate may view the details of permissions request filed by himself. The permission status and total count is displayed in this section.


← How Many Ounces in a Pound?
The 2017 Masters at Augusta National has arrived, and various storylines are hanging over the activity. Could Rickie Fowler win his first major and green coat? Or then again will Rory McIlroy beat his own evil presences to finish the profession terrific hammer? is live blogging the whole competition. Pursue the third round beneath.
For what reason does The Masters live inclusion begin so late?
As the early starters get going at The Masters every year, watchers over the globe share in a similar dissatisfaction as they recall the constrained TV inclusion on offer.
As games fans we've turned out to be progressively used to nonstop inclusion of each real occasion in the logbook. Regardless of whether it be cameras in switching rooms or mic'd up refs, there is by all accounts no piece of the match-day experience that is beyond reach nowadays.
So for what reason does the most definitely foreseen golf competition of the year evade this pattern? The appropriate response lies in the puzzling and hidden halls of Augusta National.
The club is notable for its exacting control of everything encompassing the competition – regardless of whether it be not permitting fans (or should I say supporters) to wear baseball tops in reverse or the utilization of cell phones – and TV inclusion is the same.
These principles have encouraged a demeanor of selectiveness around the occasion which just adds to the energy and expectation The Masters dependably produces.
Who is driving at Augusta?
In taking this position, the club is swearing off a huge number of dollars being offered by TV organizations quick to press each moment out of the survey open.you can check here infomation about masters live stream.
You simply need to take a gander at Sky's inclusion of The Open since it was granted the agreement to perceive how far TV executives are set up to go to give the open a definitive day's survey.
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