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Kinetics of c-Phycocyanin Reaction with Hypochlorite
Hydrochlorous acid bleaches c-phycocyanin visible absorbance with a second-order rate constant (pH 7.4) of 1.3 × 103 M−1 s−1. In excess of protein, ca...
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Journal of Protein Chemistry, Vol. 19, No. 2, 2000
Kinetics of c-Phycocyanin Reaction with Hypochlorite Cheyla Romay,1 Ricardo Gonzalez,1 Marta Pizarro,2 and Eduardo Lissi2,3 Received February 8, 2000
Hydrochlorous acid bleaches c-phycocyanin visible absorbance with a second-order rate constant (pH 7.4) of 1.3 ´ 103 M-1 s-1. In excess of protein, ca. 0.16 bilin moieties are disrupted by each reacted HOCl molecule. This indicates that the main reaction takes place at the apoprotein level, with a total rate constant (in monomeric units concentration) of 2.5 ´ 104 M-1 s-1. This rate constant is too low to provide protection to other biomolecules under physiological conditions. The reported antiinflammatory properties of phycocyanin are not then related to the removal of HOCl. On the other hand, the rather slow reaction rate with HOCl could be beneficial to its role as antiinflammatory agent since it will allow the protein to maintain its integrity at the inflammation locus. KEY WORDS: c-Phycocyanin; hypopchlorite; bilin modification; reaction rate.
acid. Several workers have shown that Pc is an efficient singlet oxygen physical quencher, with the bilin group modification only a minor reaction pathway (Tapia et al., 1999). Hypochlorous acid (HOCl) and/or its deprotonated anion (OCl-) play an important role in the immune defense system against microorganisms and also in inflammation. The antiinflammatory action of Pc could then be mediated at least in part by its capacity to remove HOCl. However, this possibility cannot be assessed since there are no data regarding the kinetics and mechanism of Pc interaction with HOCl. To know the interaction rate of the protein with this damaging metabolite it is important to establish its potential capacity to protect other valuable species and/or its ability to remain at the inflammation site (Arouma and Halliwell, 1987) exposed to rather high concentrations of the oxidant. Thermodynamic calculations predict that HOCl is both a one- and two-electron oxidant (Koppenol, 1994), and it has been shown that it readily reacts with thiol and thioether groups (Haenen and Bast, 1991), amines (Marquez and Dunford, 1994), amino acids (Pereira et al., 1973), ascorbate (Folkes et al., 1995), nucleotides (Bernofsky, 1991), and unsaturated hydrocarbons (Winterbourn et al., 1992). Pc can react
c-Phycocyanin (Pc)4 is a protein found in blue-green algae (MacColl and Guard-Friar, 1987). Phycocyanin monomers are themselves made up of two distinguishable protein subunits designated a and b. Each monomer contains three bilin chromophores, open-chain tetrapyrrols without metal complexes (Duerring et al., 1991). The bilin groups are covalently bound to the protein via cysteinyl thioether linkages. The chemical structure of the bilin chromophores is very close to that of bilirrubin, a molecule with well-known antioxidant capacity. Pc has strong antiinflammatory properties in several animal models (Romay et al., 1998; Gonzalez et al., 1999; Remirez et al., 1999; Rimbau et al., 1999; Vadiraja et al., 1998). In most inflammatory processes, associated to PMNL activation and recruiting there is a massive production of ROS, in particular singlet oxygen (from hypochlorite and hydrogen peroxide) and hypochlorous
Pharmacology Department, National Center for Scientific Research, CNIC, Havana, Cuba. 2 Chemistry Department, Faculty of Chemistry and Biology, University of Santiago, Santiago, Chile. 3 To whom correspondence should be addressed, at Departmanento de Química, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile; e-mail:[email protected]
Abbreviations: ABTS, 2,2¢-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt; DTPA, diethylenetriamine pentaacetic acid; HOCl, hypochlorous acid; Pc, c-phycocyanin; PMNL; polymorphonuclear leukocytes; OCl-; hypochlorite anion.
151 0277-8033/00/0200-0151$18.00/0 © 2000 Plenum Publishing Corporation
Romay et al.
then at the prosthetic group and apoprotein levels. HOCl has been shown to inactivate a variety of enzymes (Arouma and Halliwell, 1987) with rates that are extremely dependent upon the primary protein structure. In the present work, we have measured the rate of the reaction between Pc and HOCl and evaluated the stoichiometry of the process in terms of the number of bilin groups destroyed per HOCl molecule reacted.
2. MATERIALS AND METHODS HOCl was prepared from commercial Chlorox (5.25% NaOCl). Its concentration was estimated from the solution absorbance at high pH (e = 350 M-1 cm-1, pH 12). Phycocyanin was obtained from Arthospira maxima and purified by the method of Neufeld and Riggs (1969). Catalase from bovine liver (48700 U/mg, less than 0.01% thymol) and DTPA were Sigma products. Measurements were carried out in phosphate buffer 10 mM, pH 7.4. Absorbances were determined in a diode arrange spectrometer (Hewlett Packard 8453) employing a thermostated cubette with magnetic stirring. Disruption of the bilin groups was determined by the change in absorbance at 620 nm. Modification of catalase was evaluated by the decrease in its activity and/or by the decrease in absorbance at 430 nm. Catalase activity was estimated by the rate of hydrogen peroxide consumption. This was evaluated by the rate of absorbance decrease at 250 nm.
Fig. 1. Change in absorption spectra of a solution of c-phycocyanin incubated in the presence of 60 mM HOCl in phosphate buffer, 10 mM, pH 7.4.
3. EXPERIMENTAL RESULTS Addition of HOCl to a Pc solution produces a monotonic decrease in the visible band absorbance (see Fig. 1). This decrease takes place without significant changes in the band shape, thus allowing an estimation of the rate and extent of bilin group destruction. A typical plot of the absorbance at 620 nm versus reaction time is shown in Fig. 2. Both the rate of the process and the remaining absorbance at long reaction times depend, at a given Pc concentration, on the HOCl concentration. At high HOCl/protein ratios, the bleaching of the absorbance is total, indicating that all the bilin groups of Pc are completely disrupted. The plateau observed at long reaction times can then be ascribed to total consumption of the added HOCl. This was further evidenced by addition of extra hypochlorous acid after reaching the plateau, in experiments with low HOCl/protein ratios. A second burst of bilin group consumption takes place immediately after the new HOCl addition.
Fig. 2. Change with time of the absorbance of a c-phycocyanin solution measured at 620 nm following the addition of 60 mM HOCl. Conditions as in Fig. 1.
From the initial slopes of the absorbance decrease it is possible to obtain the rate of the bleaching process. A plot of the initial value of dA/dt against the initial absorbance is shown Fig. 3. These data were obtained at constant HOCl concentration, allowing the evaluation of the order in bilin groups from the slope of the plot. The value obtained was 1.05. Figure 4 shows reaction rate values, obtained at fixed Pc concentrations, plotted as a function of the HOCl concentration. The slope of this plot (0.95) indicates that, over all the concentration range employed, the initial rate law can be expressed as
Phycocyanin and Hypochlorite
Fig. 3. Dependence of the rate of fluorescence bleaching as a function of the initial absorbance of the sample. The rate, expresed as dA/dt, was obtained from the initial slope of an absorbance versus time plot. HOCl concentration was 64 mM in all the experiments. The best straight line shown has a slope of 1.05.
Fig. 4. Dependence of the pseudo first-order rate constant, defined by (dA/dt)/A, as a function of the initial HOCl concentration. The best straight line shown has a slope of 0.95.
Rate of bilin disruption = k(bilin) (HOCl) with k = 1.3 ´ 103 M-1 s-1 at 25°C and pH = 7.4. This is compatible with a simple bimolecular two-electron process for the disruption of the bilin groups by the HOCl/OCl- system. We have changed the pH in the range 6.8–8.0, thus changing the relationship between the protonated and deprotonated hydrochlorous acid (pKa = 7.6). The course of the reaction was similar, and no clear trend in the rate of bilin group disruption was observed. Given the possible change in protonation status of the protein over this pH range, the interpretation of these results is not straight-
153 forward and does not allow us to reach a conclusion regarding whether the active species at physiological pHs is the protonated and/or deprotonated hypo-chorous acid. The spectra given in Fig. 1 show small increases in absorbance at 470, 320, and 250 nm, with clear isosbestic points at 380 and 410 nm. This indicates that the contribution of secondary reactions is minimal, and that most of the products arise from initial protein–HOCl interactions. Simple mass balance considerations then allow us to determine the number of bilin groups destroyed per HOCl reacted. Over all the conditions employed it is obtained that, in excess of Pc, 0.16 ± 0.04 bilin groups are bleached per HOCl molecule introduced into the system. This value implies that bilin groups are not the main targets of the HOCl attack, and that most of the added acid is consumed in processes that do no modify the visible absorption of the bilin moieties. From the rate of bilin group modification and the fraction of reaction at these groups it is concluded that the total rate of Pc reaction with HOCl takes place with a rate constant kPc of (1.3 ´ 3/0.16) ´ 103 M-1 s-1 when the rate is expressed in concentration of Pc monomeric units. Protection of catalase activity has been employed to test the reactivity of different compounds toward HOCl (Arouma, 1997). Several experiments were carried out adding 250 mM HOCl to solutions containing Pc (0.5 mg/ml, 38 mM) and/or catalase (0.3 mg/ml, 5 mM). Modification of catalase can be followed either by the disruption of the heme group (measured by the decrease in absorbance at 430 nm) and/or by the loss of enzymatic activity. At the conditions employed, the rate of the process is too fast to be measured, but the stoichiometry of the process indicates that 0.012 ± 0.003 heme groups are disrupted per HOCl molecule added. Similar values were obtained by measuring the decrease in heme group absorbance or the enzymatic activity loss. This indicates that, relative to Pc, a considerably larger proportion of the HOCl is reacting with the proteic part of the molecule without modifying the integrity of the catalytic site. Experiments carried out employing both proteins indicate mutual protection, as expected from competitive reactions with the added HOCl. Although the error involved in these experiments is rather high, the data indicate that Pc reduces the loss of catalase heme groups by ca. 25%, while catalase reduces bilin group disruption by ca. 35%. If one considers the higher amount of Pc employed in these experiments, it can be concluded that HOCl reacts faster with catalase, and that Pc, at the 0.5 mg/ml level, is not able to completely protect catalase from its reaction with hypochlorous acid.
154 4. DISCUSSION The results obtained in the present work show that the bilin group is not the main target of Pc reaction with HOCl. In this regard, the behavior of Pc is similar to that reported for its reaction with singlet oxygen (Tapia et al., 1999) and contrasts with results obtained employing peroxyl radicals (Lissi et al., 2000) or ABTS radicals (C. Aliaga, unpublished results). In these systems, most of the radicals react with the bilin group and not with the apoprotein. The reaction of the apoprotein with HOCl is relatively slow and, on a milligram basis, slower than that of catalase. This can be related to the lack of free cystein groups in Pc. It has been shown that in proteins, the -SH groups are the most reactive toward HOCl (Arnhold et al., 1991), and that most enzymes are inactivated by oxidation of essential cystein groups (Winterbourn, 1985; Arnhold et al., 1990, 1993). The observed reaction of Pc apoprotein with HOCl can be related to the presence of about nine methionine groups in this molecule (Schirmer et al., 1986). Methionine groups also efficiently react with HOCl (Arnhold et al., 1991), and the inactivation of a1-antiproteinase has been associated with an oxidation of methionine residues. The reaction of the bilin group could also result from an oxidation of the ether linkage that binds the chromophore to the apoprotein (Arnhold et al., 1990). However, the total bleaching of the visible absorbance associated with the reaction at the prosthetic group level would favor an oxidation of the double bond system of the tetrapyrrol system, as found in its reaction with singlet oxygen (Braslavsky et al., 1991). Regarding the possible removal of HOC1 by Pc as part of its function as antiinflammatory agent, we consider that the rate of the process is too slow to significantly reduce the damage associated with HOCl in inflammatory processes. In fact, the reaction rate found in the present work is several orders of magnitude smaller than that of other biomolecules, such as ascorbic acid and glutathione (Folkes et al., 1995). Also, the small degree of protection afforded to catalase by rather high (0.5 mg/ml) concentrations of Pc found in the present work argues against an antiinflammatory action based on the removal of HOCl. On the other hand, a rather slow rate of reaction of Pc toward HOCl and singlet oxygen (Tapia et al., 1999) could be beneficial, since it will allow the protein to maintain its integrity at the inflammation locus.
ACKNOWLEDGMENTS This work was supported by FONDECYT (1970691) and a Catedra Presidential en Ciencias, 1996.
Romay et al. REFERENCES Arnhold, J., Hammerschmidt, S., Wagner, M., Mueller, S., Arnold, K., and Grimm, E. (1990). On the action of hypochlorite on human serum albumin. Biomed. Biochim. Acta 49, 991–997. Arnhold, J., Hammerschmidt, S., and Arnold, K. (1991). Role of functional groups of human plasma and luminol in scavenging of NaOCl and neutrophil-derived hypochlorous acid. Biochim. Biophys. Acta 1097:145–151. Arnhold, J., Mueller, S., Arnold, K., and Sonntag, K. (1993). Mechanisms of inhibition of chemiluminescence in the oxidation of luminol by sodium hypochlorite. J. Biolumin. Chemilumin. 6, 307–313. Aruoma, O. I. (1997). Scavenging of hypochlorous acid by carvedilol and ebselen in vitro. Gen. Pharmacol. 28, 269–272. Aruoma, O. I., and Halliwell, B. (1987). Action of hypochlorous acid on the antioxidant protective enzymes superoxide dismutase, catalase and gluthatione peroxidase. Biochem. J. 248, 973–976. Bernofsky, C. (1991). Nucleotide chloramines and neutrophil-mediated cytotoxicity. FASEB J. 5, 295–300. Braslavsky, S. E., Schneider, D., Heihoff, K., Nonell, S., Aramendia, P. F., and Schaffner, K. (1991). Phytochrome models. 11. Photophysics and photochemistry of phycocyano bilin dimethyl ester. J. Am. Chem. Soc. 113, 7322–7334. Duerring, M., Schmidt, G. B, and Huber R. (1991). Isolation, crystallization, crystal structure analysis and refinement of constitutive c-phycocyanin from chromatically adapting cyanobacterium Fremyella diplosiphon at 1.66 Å resolution. J. Mol. Biol. 217, 577–592. Folkes, L. K., Candeias, L. P., and Wardman, P. (1995). Kinetics and mechanisms of hypochlorous acid reactions. Arch. Biochem. Biophys. 20, 120–126. González, R., Rodríguez, R. S., Romay, Ch., Ancheta, O., González, A., Armesto, J., Remirez, D., and Merino, N. (1999). Antiinflammatory activity of phycocyanin extract in acetic acid induced colitis in rats. Pharmacol. Res. 39, 55–59. Haenen, G. R. M. M., and Bast, A. (1991). Scavenging of hypochlorous acid by lipic acid. Biochem. Pharmacol. 42, 2244–2246. Koppenol, W. H. (1994). Thermodynamic considerations on the formation of reactive species from hypochlorite, superoxide and nitrogen monoxide. Could nitrosyl chloride be produced by neutrophils and macrophages? FEBS Lett. 347, 5–8. Lissi, E. A., Pizarro, M., Aspée, A., and Romay, Ch. (2000). Kinetics of phycocyanin bilin groups destruction by peroxyl radicals. Free Rad. Biol. Med., (in press). MacColl, R., and Guard-Friar, D (1987). Phycobiliproteins, CRC Press, Boca Raton, Florida. Marquez, L. A., and Dunford, H. B. (1994). Chlorination of taurine by myeloperoxidase J. Biol. Chem. 269; 7950–7956. Neufeld, G. J., and Riggs, A. F. (1969). Aggregation properties of c-phycocyanin from Anacystis nidulans. Biochem. Biophys. Acta 181, 234–243. Pereira, W. E., Hoyano, Y., Summons, R. E., Bacon, V. A., and Duffield, A. M. (1973). Chlorination studies. II The reaction of aqueous hypochloruos acid with a-amino acids and dipeptides. Biochim. Biophys. Acta 313, 170–180. Remirez, D., González, A., Merino, N., González, R., Ancheta, O., Romay, Ch., and Rodríguez, S. (1999). Effect of phycocyanin in zymosaninduced arthritis in mice. Drug Dev. Res. 48, 70 –75. Rimbau, V., Camins, A., Romay, Ch., González, R., and Pallas, M. (1999). Protective effects of phycocyanin against kainic acidinduced neuronal damage in rat hippocampus. Neurosci. Lett. 276, 75 –78. Romay, C., Ledón N., and González, R. (1998) Further studies on antiinflammatory activity of phycocyanin in some animal models of inflammation. Inflamm. Res. 47, 334–338. Schirmer, T., Huber, R., Schneider, M., Bode, W., Miller, M., and Hackert, M. L. (1986). Crystal structure analysis and refinement at 2.5 Å of hexameric c-phycocyanin from the cyanobacterium Agmenellum quadruplicatum. The molecular model and its implications for light-harvesting. J. Mol. Biol. 188, 651–676.
Phycocyanin and Hypochlorite Tapia, G., Galetovic, A., Lemp, E., Pino, E., and Lissi, E. A. (1999) Singlet oxygen mediated photobleaching of the prosthetic group in hemoglobins and c-phycocyanin. Photochem. Photobiol. 70, 499–504. Vadiraja, B. B., Gaikwad, N. W., and Madyastha, K. M. (1998). Hepatoprotective effect of phycocyanin: Protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicity in rats. Biochem. Biophys. Res. Commun. 249, 428–431.
155 Winterbourn, C. C. (1985). Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarities of the oxidant hypochlorite. Biochim. Biophys. Acta 840, 204–210. Winterbourn, C. C., van den Berg, J. J. M., Roitman, E., and Kuypers, F. A. (1992). Chlorohydrin formation from unsaturated fatty acids reacted with hypochlorous acid. Arch. Biochem. Biophys. 296, 547–555.


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Science, Tech, Math › Animals & Nature
Amphicyon
Wally Gobetz/flickr
Prehistoric Mammals
Paleontologists
Dinosaurs & Birds
Marine Reptiles
Habitat Profiles
Bob Strauss
Science Writer
B.S., Cornell University
Bob Strauss is a science writer and the author of several books, including "The Big Book of What, How and Why" and "A Field Guide to the Dinosaurs of North America."
Amphicyon (Greek for "ambiguous dog"); pronounced AM-fih-SIGH-on
Plains of the northern hemisphere
Historical Epoch:
Middle Oligocene-Early Miocene (30-20 million years ago)
Size and Weight:
Varies by species; up to six feet long and 400 pounds
Omnivorous
Distinguishing Characteristics:
Large size; bear-like body
About Amphicyon
Despite its nickname, the "Bear Dog," Amphicyon was directly ancestral to neither bears nor dogs. This was the most prominent genus of the family of mammalian, vaguely canine-like carnivores that succeeded the larger "creodonts" (typified by Hyaenodon and Sarkastodon) but preceded the first true dogs. True to its nickname, Amphicyon looked like a small bear with the head of a dog, and it probably pursued a bear-like lifestyle as well, feeding opportunistically on meat, carrion, fish, fruit, and plants. The front legs of this prehistoric mammal were especially well-muscled, meaning it could probably stun prey senseless with a single well-aimed swipe of its paw.
Befitting a mammal with such a lengthy provenance in the fossil record--about 10 million years, from the middle Oligocene to the early Miocene epochs--the genus Amphicyon embraced nine separate species. The two largest, the appropriately named A. major and A. giganteus, weighed up 400 pounds fully grown and roamed the expanse of Europe and the near east. In North America, Amphicyon was represented by A. galushai, A. frendens, and A. ingens, which were slightly smaller than their Eurasian cousins; various other species hailed from modern-day India and Pakistan, Africa, and the far east. (The European species of Amphicyon were identified in the early 19th century, but the first American species was only announced to the world in 2003.)
Did Amphicyon hunt in packs, like modern wolves? Probably not; more likely this megafauna mammal stayed well out of the way of its pack-hunting competitors, contenting itself with (say) piles of rotting fruit or the carcass of a recently deceased Chalicotherium. (On the other hand, oversized grazing animals like Chalicotherium were themselves so slow that elderly, sick or juvenile herd members could easily be picked off by a solitary Amphicyon.) In fact, it's likely that the Bear Dog faded from the world scene 20 million years ago, at the end of its long reign, because it was displaced by better-adapted (i.e., faster, sleeker, and more lightly built) hunting animals.
Facts of the Pre-Historic Predator Hyaenodon
Barbourofelis
Prehistoric Dog Pictures and Profiles
Cynodictis
Chalicotherium Facts and Figures
The 10 Best Prehistoric Nicknames
What Was an Entelodon?
40 Million Years of Dog Evolution
Proconsul Facts and Figures
Mesohippus
Horned Gopher (Ceratogaulus)
Prehistoric Marsupial Pictures and Profiles
Giant Mammal and Megafauna Pictures and Profiles
Epicyon
The Dinosaurs and Prehistoric Animals of Nebraska
Saber-Toothed Cat Pictures and Profiles


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Q: Remove chars from a string I have the following function but I want it to do the opposite eg return the bad chars not the ones I specify
This function lets you specify a two strings. The string you want to parse and a string of chars that you would like to keep from the first string specified - The edited string is returned
Function GETALPHANUMERIC(text, str_all)

 For lenstr = 1 To Len(text)
     If InStr(str_all, LCase(Mid(text, lenstr, 1))) Then
         GETALPHANUMERIC = GETALPHANUMERIC & Mid(text, lenstr, 1)
     End If
 Next

 End Function

Thanks
Rob

A: Just add = 0 :
If InStr(str_all, LCase(Mid(text, lenstr, 1))) = 0 Then

The InStr function returns 0 when no match is found.

A: You could use the split function like in the example below.
Sub test()

  Dim s As String
  Dim result As String

  s = "abcXdefXghiX"
  result = excludeCharacter(s, "X")

  MsgBox s & " excluding X is " & result

End Sub

Function excludeCharacter(originalString As String, exclude As String) As String

  Dim sArray() As String
  Dim result As String
  Dim i As Long

  sArray = Split(originalString, exclude)

  For i = 0 To UBound(sArray, 1)
    result = result & sArray(i)
  Next i

  excludeCharacter = result

End Function

A: Also just wrote this too - thought I would share just incase
Function BadChar(text, str_all)

     For lenstr = 1 To Len(text)
     If InStr(str_all, LCase(Mid(text, lenstr, 1))) = 0 Then
         BadChar = BadChar & Mid(text, lenstr, 1)
     End If
Next

End Function

A: In other words, you want to strip out (remove) characters from the source string? If so, here's an answer for that:
Function StripChars(source As String, chars As String)
    Dim pos As Long
    For i = 1 To Len(chars)
        Do
            pos = InStr(1, source, Mid(chars, i, 1), VbCompareMethod.vbTextCompare)
            If pos > 0 Then
                source = Mid(source, 1, pos - 1) & Mid(source, pos + 1)
            Else
                Exit Do
            End If
        Loop
    Next i
    StripChars = source
End Function

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text:
Home Business assignment Mr. X is 19 y/o sophomore in college
Mr. X is 19 y/o sophomore in college
The following case is quite typical of S.O cases we see related to college student sexual offending:
Mr. X is 19 y/o sophomore in college. He was recently found guilty of sexual assault and is currently incarcerated. Five months ago he and his roommates had a large party at their house. Everyone was drinking and having fun. Mr. X met Ms. Y and they started talking. A few hours later, the two went to Mr. X's room and begin "making out". This went on for about 20 minutes, and Mr. X became sexually aroused. He wanted to have sex, and believed Ms. Y wanted to have sex, as well. During his pre-sentence investigation he stated, "why would she come up to my room, make out with me, and lead me on if she didn't want to have sex? She was giving me all the signs that she wanted it. Women play too many games. They're always sending men mixed messages and then we're the ones who get in trouble. It's not fair!"
Mr. X took off his pants and began to take off Ms. Y's pants, but she said "no." He perceived her "no" as a "yes" (after all, according to him, she was giving him all the signs of wanting to have sex) and proceeded to take off her pants, push her onto the bed, and have sexual intercourse with her against her will. She did not fight back, but as soon as it was over, she got dressed and ran out of the room crying.
Mr. X shows up in your treatment program and it is your job to help him understand some of the causal mechanisms behind his offense. (Remember: Avoid using the first-person to explain your answer. Make your argument and support it with evidence)
1) What are Mr. X's risk factors? Why are they risk factors for him, specifically?
2) Next, review your list of thinking errors/cognitive distortions and list all that apply to Mr. X.
Instructions for Ordering
The following case is typical of S.O. cases involving sexual offenses by college students:
Mr. X is a 19-year-old college sophomore. He was recently convicted of sexual assault and is currently serving his sentence. He and his roommates threw a big party at their place five months ago. Everyone was having a good time and drinking. Mr. X met Ms. Y and the two began conversing. After a few hours, they went to Mr. X's room and started "making out." Mr. X became sexually aroused after about 20 minutes of this. He wanted to have sex, and believed Ms. Y wanted to have sex, as well. During his pre-sentence investigation he stated, "why would she come up to my room


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UMC is the largest referral center in the region for endoscopy and colonoscopy procedures and screenings. Dr. Texas Tech Physicians of Lubbock is a top-tier medical practice based on quality care and patient satisfaction. Comprised of over 130 providers representing all primary care specialties. Rafiul Islam is a gastroenterologist in Lubbock, Texas and is affiliated with University Medical Center-Lubbock. 775. Leverage your professional network, and get hired. It serves as the primary teaching hospital for the Texas Tech University Health Sciences Center (TTUHSC). We specialize in preventing, diagnosing and treating conditions related to the digestive/gastrointestinal (GI) tract. LUBBOCK -- Eight people were injured and several wings of University Medical Center were evacuated because of a fire and explosion Thursday. University Medical Center in Lubbock, TX procedure pricing information for a Laparoscopic Hernia Repair Surgery - Groin or Abdomen can be found listed below. New Registered Nurse careers in Lubbock, TX are added daily on SimplyHired. 17 Registered Nurse Prn jobs available in Lubbock, TX. Oliva graduated from the Texas Tech University Health Science Center School of Medicine - Lubbock in 1989. SPEC is the first and only single- specialty Dr. 9262) prior to your procedure. Turnover rates at University Medical Center are the lowest they've ever been and patient satisfaction is in the 94th percentile in the nation. UMC taps Cerner for 10-year EHR stint | Healthcare IT News The Comprehensive Pulmonary Hypertension Center (CPHC) at UMC New Orleans was awarded top-tier accreditation from the Pulmonary Hypertension Association (PHA). See reviews, photos, directions, phone numbers and more for Umc Hospital Icu locations in Lubbock, TX. UMC's Center for Diagnostic and Advanced Endoscopy performs endoscopic procedures and a range of services for patients undergoi UMC Health System - 602 Indiana Ave, Lubbock, Texas 79415 - Rated 4. Find your next job near you & 1-Click Apply! South Plains Endoscopy Center, Lubbock, TX, 79410, 806-797-1015 Find, Rate, or Review South Plains Endoscopy Center, Lubbock, Texas Registered Nurse Aveanna Healthcare - Lubbock, TX. For complete driving directions, use Google Maps. Umc Health System in Lubbock, TX - Lubbock County is a business listed in the categories Hospitals and General Medical And Surgical Hospitals and offers Free Medical Advice Hotline and 24/7 Free Medical Advice Hotline. 9378 West Wind Primary Health Center 5520 4th Street 806. Lubbock Texas Gastroenterologist Doctors physician directory - Endoscopy is procedure that UMC Children's Hospital Brownfield Regional Medical Center . Welcome The Division Gastroenterology is part of the Department of Internal Medicine, Texas Tech University Health Sciences Center (TTUHSC) at El Paso Campus, Paul L. Finding medical care in Lubbock ^ Covenant Health. Las Vegas, NV 89102. Houssam Al Kharrat has a 2. 8200. 0475 I-27 Medical Center 4105 I-27 806. 762. , radiology, poor, and public UMC Physicians is a physician practice management group in Lubbock Texas. The low-stress way to find your next Registered Nurse job opportunity is on SimplyHired. Lake Ridge Primary Health Center 5130 82nd Street 806. Endoscopy Services. Umc Children's Hospital is located at Po Box 5980. These doctors are experts on how food moves through the digestive system and is chemically broken down, with nutrients being absorbed and waste excreted. g. With us, you'll receive the highest quality, most advanced health care available from expert doctors who are teaching the next generation of medicine at the Texas Tech University Health Sciences Center. Cataract Surgical Center of Lubbock 5109 80th St South Plains Endoscopy Center 3610 24th Street Lubbock, TX 79410 (806) 793-3141 University Medical Center Abilene Endoscopy Center Ambulatory Surgical Center Community Health Center of Lubbock Federally Qualified Health Center (FQHC) University Medical Center UMC Oncologists in Lubbock, TX Oncologists diagnose cancer through methods such as biopsy, endoscopy, X-ray, blood tests, ultrasound, and different forms of nuclear UMC Southwest Gastroenterology. edu. SPEC is the first and only single-specialty Ambulatory Center in Lubbock, Texas. Lodging near Umc Children's Hospital are listed below ordered by distance (closest at the top). Browse 49 UMC NURSE Jobs ($45K-$126K) hiring now from companies with openings. 8600. About Us. One more procedure, maybe two, and I should have some relief. 2633 Milwaukee Family Medicine 7301 Milwaukee Ave. Our New Years resolution for 2019 is to show gratitude. Jabor's Biography — Dr. 806. has announced a 10-year extended and enhanced relationship to align EHR and Clinical IT teams at UMC, Texas Tech Physicians of There are 157 clinic/center registered providers in Lubbock, TX. UMC is on the North (left) side of the road; From the North via I-15. University Medical Center in Lubbock, Texas is a public, non-profit 500-bed hospital. University Medical Center in Lubbock, TX - Get directions, phone number, research physicians, and compare hospital ratings for University Medical Center on Healthgrades. Umc Children's Hospital Texas Specialty Hospital Covenant Women's & Children's Covenant Medical Group University Medical Center Covenant Medical Center Ark Hospital For Pets Lubbock Plastic Surgery Assoc South Plains Endoscopy Center High Plains Surgery Center Grace Medical Center Highland Community Hospital North Star Surgical Center Dr. Thanks in advance. 1800 West Charleston Blvd. Al-Tamimi is a gastroenterologist in Lubbock, Texas and is affiliated with University Medical Center-Lubbock. Banner - University Medical Center Lubbock, TX, US. Find your next job opportunity near you & 1-Click Apply! Ratings & Patient Reviews for Umc Health System, Lubbock, Texas, 602 Indiana Avenue, TX, Health Networks Systems, Teaching Hospital, Burn Centers, Specialty Clinics Overview. Family Practice, Family Practice with Obstetrics, Internal Medicine, and Pediatrics. It is our mission to extend Christian ministry by caring for the whole person—body, mind and spirit—and by working with others to improve health and quality of life in our communities. The Department of Surgery also offers annual visiting lectureships hosted by the divisions of General Surgery, Plastic Surgery and Urology. 2 weeks ago; Drain Technician CSNA Architects Lubbock, TX, US. Our New Orleans hospital is always interested in dedicated professionals. . Find your perfect job & apply. UMC Health System | 602 Indiana Avenue | Lubbock, TX 79415 | 806. University Medical Center, in Lubbock, Texas, has signed Cerner to a decade-long deal to expand and enhance its existing Cerner electronic health record system. Find UMC Health System jobs on Glassdoor. New Registered Nurse Prn careers in Lubbock, TX are added daily on SimplyHired. Lubbock, TX 79416 | Map Dr. Find deals and phone #'s for hotels/motels around South Plains Endoscopy Center. View reviews of UMC Health System written by nurses. Visit RateMDs for Dr. Sameer Islam was born in Malone, New York but grew up in his home town of Odessa, Texas. Work requires occasional exerts up to 10 lbs. 8668. See salaries, compare reviews, easily apply, and get hired. com. Any feedback would be most welcome. Covenant Medical Center, 3615 19th St. After you do business with Umc Health System, please leave a review to help other people and improve hubbiz. org. umc. Initial reports of the fire came in just after 10 a. m. He works in Lubbock, TX and speciali Find the Best Lubbock, TX Clinics on Superpages. Covenant Health is the most comprehensive health care network serving West Texas and Eastern New Mexico. Providers. UMC Health System is the leader in comprehensive healthcare delivery in West Texas and Eastern New Mexico. Hotels near or close to South Plains Endoscopy Center in Lubbock Texas area. COMMUNITY EVENT FOR COLON CANCER AWARENESS -Brought to you by the University Medical Center Endoscopy Department. Hamed Al-Tamimi is a Gastroenterologist in Lubbock, TX. Endoscopy Outpatient Lubbock, Texas 79415 UMC Health System is the leader in comprehensive healthcare delivery in West Texas and Eastern New Mexico. Take a look at all 7 of our physicians at Lubbock Digestive Disease Associates. Today's top 118 Umc Hospital Nurse jobs in United States. Lubbock, TX 79415. Hospital. Providers Located in: Lubbock, Texas Click on a provider's name to obtain a detailed and comprehensive profile, including affiliations, publications, patient care statistics, services and procedures provided, drug prescribing statistics, and open payments received. The Texas Tech University Health Sciences Center (TTUHSC) campus in Lubbock offers students the opportunity to expand knowledge in five schools that are on the forefront of health care education. A gastroenterologist is a specialist in diagnosis and treatment of conditions involving the digestive/gastrointestinal (GI) tract. The Medical Center has invested in state-of-the-art technology, recruited skilled nurses and partnered with Board-Certified physician experts to create the region's most advanced gastroenterology facility in El Paso. Find a Gastroenterologist near you in Lubbock, TX. Our Location and Contact Info. hospital offers rooms which include amenities such as televisions, telephones, and wi-fi, and access to 24/7 registered nursing care. The low-stress way to find your next Registered Nurse Prn job opportunity is on SimplyHired. 118 UMC Health System jobs including salaries, ratings, and reviews, posted by UMC Health System employees. Harnar Burn Unit – 806. 794. Interactive Campus Map Parking Information. UMC is the primary hospital of the MC Health System and is owned by the taxpayers of Lubbock County. LOCATION OF YOUR PROCEDURE: UMC's Endoscopy Center(4THFloor of UMC'S East Tower) TIME OF YOUR PROCEDURE: • You will receive a call from UMC's ENDOSCOPY CENTER (806. Apply to Faculty, Billing Coordinator, Endoscopy Technician and more! Find 6 listings related to Southwest Regional Medical Center in Lubbock on YP. UMC New Orleans is an Advanced Primary Stroke Center with a full stroke team on call 24/7 to immediately care for patients with stroke symptoms. Lubbock Texas Gastroenterologist Doctors physician directory - Learn about the colonoscopy procedure, preparation, post procedure, side effects, and risk information. 1 based on 1,047 Reviews "We are currently here and from the moment we went in the ER Located in the same facility, South Plains Endoscopy Center is a convenient option, should a procedure be required. Diseases that may be diagnosed with capsule endoscopy include small intestinal tumors, Crohn's disease, and angiodysplasias. Located in the same facility, South Plains Endoscopy Center is a convenient option, should a procedure be required. Goyal is a fellowship trained bariatric/ MIS / general surgeon who has been in practice for the past 4 years in Rhode Island focusing on advanced laparoscopic procedures , bariatric surgery and endoscopy. (806 ) 761 – 0747 •Endoscopic Retrograde Cholangiopancreatography (ERCP). These services are dedicated to our valued constituents: the Medical Center's faculty, staff and students, and, particularly, the people of Mississippi. Miled Jabor, MD is a Gastroenterology Specialist who practices in Lubbock, TX. Find a cost comparison to other providers in Lubbock, TX and see your potential savings. General Information: 601-984-1000 Patient Appointments: 888-815-2005 For Nurses Welcome from the Chief Nursing Executive/Vice President. UMC Health System is located in Lubbock, Texas. Covenant Health's Endoscopy Center is a state-of-the-art facility for the outpatient diagnosis and treatment of respiratory and digestive tract diseases. Take I-15 South to West Charleston Blvd. I am primarily focused on THR Presby as a potential work place. Banner - University Medical Center South Welcome to Banner – University Medical Center South, formerly University of Arizona Medical Center – South Campus, is an academic medical center focused on providing exceptional patient care, teaching future health care professionals and conducting groundbreaking research to help the people of Arizona and beyond. UMC president and CEO David Allison said employee Find a General Surgeon near you in Lubbock, TX. He completed both his medical degree (MD) and masters of business association (MBA) at Texas Tech University Health Sciences Center and Texas Tech R An agreement between Lubbock Christian University and the Texas Tech University Health Sciences Center will allow for LCU honors students to apply early to the HSC's medical school, granting pre-admission and exemption from a medical entrance exam. See all Gastroenterologist office locations in Lubbock, doctor ratings and insurance accepted. 1 like. Center for Diagnostic and Advanced Endoscopy. Covenant Endoscopy--Jesse Flores, ST Grace Medical Center--Morgan Williams, CST Lubbock Heart & Specialty Hospital--Julia Rodriguez, CST University Medical Center--Amy Brunton, CST The ceremony concluded with the new Surgical Technologists reciting The Surgical Technologist Pledge before co-professionals and family. UMC Level 1 From newborns to grandparents, UMC Southwest Gastroenterology has the staff and physicians to care for you and your entire family. UMC Southwest Cancer Center – 806. Reasons for colonoscopy include investigation of rectal bleeding, colon polyps, diarrhea, and other diseases and conditions. , 725-9200 University Medical Center - UMC Health System Nursing . 406 University Medical Center jobs available in Lubbock, TX on Indeed. © 2016 UMC Health System. See reviews, photos, directions, phone numbers and more for Southwest Regional Medical Center locations in Lubbock, TX. Foster School of Medicine's Department of Surgery, and serves as the Division Chief of Oral and Maxillofacial Surgery (OMS) at Texas Tech University Health Sciences Center El Paso, and Medical Director of Oral and Maxillofacial Surgery at University Medical Center in El Paso. May involve walking and/or pushing patients for transport purposes in the Endoscopy Center or to the prep area. Treatment clinic for gastroenterology conditions for Texas Tech Physicians of Lubbock. The Surgical Hospital at Southwoods , Youngstown, Ohio The University of Texas MD Anderson Cancer Center , Houston, Texas He is an Associate Professor of Surgery in the Paul L. Registered Nurse (RN) *Now Offering Paid Time Off (PTO) Benefits* Aveanna Healthcare, the largest pediatric home health care company in the U. 4/5 rating from patients. , is hiring compassionate Registered Nurses (RN) to provide skilled nursing care to patients in the home setting. Welcome to UMC Southwest Gastroenterology From newborns to grandparents, UMC Southwest Gastroenterology has the staff and physicians to care for you and your entire family. Lubbock Texas Gastroenterologist Doctors physician directory - Endoscopy is procedure that allows a doctor to examine the esophagus, stomach and duodenum, which can help to detect digestive disorders, for example, hiatal hernia, GERD, cancer, and stomach (peptic) ulcers. 2500 North State Street Jackson, MS 39216 www. 761. Ted Dr - Lubbock Digestive Disease Associates. 404 University Medical Center jobs available in Lubbock, TX on Indeed. 129 UMC Health System jobs, including salaries, reviews, and other job information posted anonymously by UMC Health System employees. I love Dallas, but I want to be happy working there. Browse 36 LUBBOCK, TX ENDOSCOPY NURSE job ($63K-$93K) listings hiring now from companies with openings. com - a better job search experience. See all General Surgeon office locations in Lubbock, doctor ratings and insurance accepted. Colorectal cancer is one of the most preventable and treatable forms of cancer when it's found early. He completed his undergraduate studies at the University of Texas in Austin where graduating with honors. • If you receive a voicemail from UMC's Endoscopy Center, call them as soon as you can. Search job openings at UMC Health System. As vital members of the healthcare team, nurses incorporate collaboration, clinical practice, and a culture of caring to support patient and family-centered care. Give us a call or fill out a contact request with any questions. Apply to Patient Transporter, Office Assistant, Texas Works Advisor and more! Read more about possibilities for an exciting career at University Medical Center New Orleans. Skills and Abilities Hotels Near Umc Children's Hospital - Umc Children's Hospital Texas. UMC is a hospital that our region trusts for exceptional healthcare services and expertise. Get hired. Back to Top. Download UMC Pregnancy on the App Store or Google Play to empower you in your & baby's health! X UMC Endoscopy Center, Lubbock, Texas. of force and frequent exerts of small amounts of force to lift, carry, push, pull, and move objects. Houssam Al Kharrat reviews, contact info, practice history, affiliated hospitals & more. Click here if you need current payor information? Does your office need a provider education manual? Does your office need patient chart stickers for our inpatient labs? Are you moving and need to notify us? Do you need contact information for our payors? Do you have questions about TeamChoice reimbursement? Clinic/Center in Lubbock, Texas. , 725-0000. New Umc Hospital Nurse jobs added daily. He received his medical degree from Texas Tech University Health Sciences Center Lubbock Texas Gastroenterologist Doctors physician directory - Read about capsule endoscopy, a tiny capsule the size of a large pill that is swallowed and takes pictures of the small intestine. 2 weeks ago; Endoscopy Technician University Medical Center Lubbock, TX, US. Learn about their education and certifications in the field. More than University Medical Center is once again bringing a higher level of care to the El Paso community and surrounding region. UMC Physicians is a physician practice management group in Lubbock Texas. Giant Colon onsite to run through during the race. Miled Jabor, MD is affiliated with Covenant Medical Center - 19th Stree A hospital's overall Gastroenterology & GI Surgery score is based on various data categories, including volume of high-risk patients, nurse staffing and patient survival. University Medical Center in Lubbock, TX procedure pricing information for an Upper GI Endoscopy can be found listed below. Rafiul Sameer Islam graduated from Texas Tech University Health Sciences Center School of Medicine in 2008 before completing a residency in Internal Medicine at Texas Tech University Health Sciences Center in Lubbock, TX from 2008 to 2011. We're the original doctor ratings site with over 2 million reviews. University Medical Center (UMC) Health System and leading health information technology supplier, Cerner Corp. Work involves sitting most of the time while working on computers. University Medical Center of El Paso -- We care for El Paso. Covenant Children's, 4000 24th St. 0464 UNIVERSITY MEDICAL CENTER LUBBOCK, TEXAS Human Resources UMC Walk-In Clinics Available Get reviews, hours, directions, coupons and more for South Plains Endoscopy Center at 3610 24th St, Lubbock, TX 79410. UMC is on the North (right) side of the road; University Medical Center of Southern Nevada. UMC Timothy J. Full details of health providers NPPES records in Lubbock , Texas. The 50 top-scoring Find 4 listings related to Umc Hospital Icu in Lubbock on YP. General Gastroenterology, Advanced Endoscopic Interventional Society of American Gastrointestinal Endoscopic Surgeons University Health Sciences Center, Department of Anesthesiology, Lubbock, Texas, April 2009. Covenant Specialty Hospital, 3815 20th St. S. Lubbock Heart & Surgical Hospital, NorthStar Surgical Center, Cardiologists of Lubbock and Texas Physicians Group are not responsible for injuries or damages you may incur as a result of you stopping medical treatment or your failure to obtain medical treatment. Find nursing jobs and salary information on Nurse. I love my job at UMC but I hate Lubbock. Hey guys, I am considering making a move to the Dallas area from Lubbock. Open positions available often include employment opporunities such as Geriatric Charge Nurse (RN), Licensed Vocational Nurse Geriatric Trauma, Registered Nurse (RN) Geriatric Trauma, Registered Nurse Post Anesthesia Care Unit, Registered Nurse Medical Intensive Care Unit, Registered Nurse About Umc Southwest Medical: Umc Southwest Medical is located at 4004 82nd St FL 1 in Lubbock, TX - Lubbock County and is a business listed in the categories Hospitals and General Medical And Surgical Hospitals. Foster School of Medicine (PLFSOM), and the University Medical Center (UMC) of El Paso. [01/04/19] Lubbock Digestive Disease Associates along with South Plains Endoscopy Center wishes our patients, families and employees a healthy and prosperous New Years. Jobs. Clinic/Center is irregularly defined, sometimes being limited to organizations serving specialized treatment requirements or distinct patient/client groups (e. Love your job. 0464 UNIVERSITY MEDICAL CENTER LUBBOCK, TEXAS Human Resources UMC Walk-In Clinics Available Lake Ridge Primary Health Center 5130 82nd Street 806. Print this Parking Map for directions. Search for other Surgery Centers in Lubbock on The Real Yellow Pages®. We are proud to help patients throughout the Lubbock, TX area University Medical Center (UMC) Health System and Cerner Corp. Oliva graduated from the Texas Tech University Health Science Center School of Medicine - Lubbock in 1989 The Eye Surgery Center of Nashville, Nashville, Tenn. Dimensions/Women's Health – 806. Michelle Owen is feeling positive at UMC Endoscopy Center. Kensing, Kelly Dr - South Plains Endoscopy Center. 602 Indiana; Lubbock, Texas 79415 UMC Endoscopy Center, Lubbock, Texas. UMC is the primary hospital of the MC Health System and is owned by the Address. This patient-focused environment emphasizes comfort and convenience throughout the examination and recovery process. After you do business with Umc Southwest Medical, please leave a review to help other people and improve hubbiz. , have agreed to a 10-year extended and enhanced relationship to align electronic health record (EHR) and clinical IT teams at UMC, Texas Tech Physicians of Lubbock and UMC Physicians Network Services (PNS). 8660. View umc health system jobs in Lubbock, Texas from employers who want to hire YOU. Local Medical Clinics & Centers in Lubbock,TX with maps, local business reviews, directions and more. A facility or distinct part of one used for the diagnosis and treatment of outpatients. More than 300,000 patients a year have come to expect our dedication to service and the top-tier care we provide. He is 59 years old and has been practicing for 32 years. 308 Registered Nurse jobs available in Lubbock, TX. Screenings are powerful tools for early detection. Search or browse RateMDs for trusted reviews & ratings on Gastroenterologists in Lubbock. I've officially been violated! Thank you Joleigh for 4 years of pain. UMC is the only hospital in El Paso to be twice named one of America's Top 100 Hospitals. Review our gastroenterology procedures or book a GI test today. Search for cheap and discount hotel rates near Umc Children's Hospital (Umc Children's Hospital) for your upcoming individual or group travel. They will inform you what time you need to arrive. At Covenant Health, nursing is an integral part of the organizational operation. umc endoscopy center lubbock
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text:
Utah politicians must be held accountable following the attack on the U.S. Capitol
Accountability/Transparency, Better Utah Staff, Blog
On January 6th, we saw the consequences of leaders who put the pursuit of power over the principles and norms that form the foundations of our democracy. Trump may have been the one who incited the mob to descend upon the Capitol in frenzied insurrection. But there are plenty more who must shoulder the blame for the parts they played over the past four years that led to one of the darkest days in our nation's history.
One of the most complicit is Representative Chris Stewart, who spent his past two terms in office reinforcing the view that it's okay to support "our Mussolini" as long as your party can stay in power and achieve its desired policy outcomes. Quickly ensnared within Trump's "cult of personality," Stewart reveled in his newfound role of vehemently defending some of the President's worst impulses. He repeatedly spread and amplified the false claims undermining the legitimacy of the 2020 election, going so far as to attempt to overturn Pennsylvania's presidential election results only hours after the violent mob ransacked the building where he cast his undemocratic vote.
Equally complicit is newly-elected Burgess Owens, who, only days after taking an oath to support and defend the Constitution, also voted to overturn the results of a democratic election in an effort to keep an increasingly unhinged autocrat in the White House. As one of his first official acts, this vote is enough to define his legacy as a congressman from Utah, but it should not be forgotten that Owens spent his campaign legitimizing an online cult and an online cult and bizarre conspiracy theories that have resulted in a growing number of Americans living in an alternate reality constructed with "alternate facts."
Meanwhile, Senator Mike Lee has used his platform to stoke conspiratorial fears about the federal government, including publishing a book that argues Americans must fight back against the so-called "deep state." Utah's self-described "constitutional scholar" declined to participate in the election heist this week, but he has repeatedly chosen to invent "scholarly" arguments that could be used to defend Trump's latest attack on our democratic norms and constitutional principles. Lee's influence could be seen this week as a member of the mob raised the "Title of Liberty" outside the Capitol building, a clear tribute to the man who Senator Lee likened to Captain Moroni only months before.
While the spotlight has given our federal lawmakers more opportunities to show their priorities and loyalties, other politicians closer to home have also contributed in their own ways to enabling and normalizing the Trump era. Utah Attorney General Sean Reyes, a devoted Trump loyalist, eagerly used personal time to meddle with the votes of our neighboring Nevadans before joining his fellow members of the Republican Attorney Generals Association in an unprecedented lawsuit asking the Supreme Court to negate the votes of millions of Americans in battleground states. After Trump was impeached by the House, Senate President Stuart Adams, co-chair of Trump's re-election efforts in Utah, and House Speaker Brad Wilson issued a citation letter praising Trump after he was impeached.
These Utah politicians supported Trump explicitly, even enthusiastically. But there were also many more who sat by quietly, never using their platform to denounce Trump or what he stood for. They brushed him off as if he were a sideshow or an aberration, rather than the top-most ranking member of their own party.
This is not a blanket condemnation of all Republicans. As Senator Mitt Romney has proven time and time again, it is entirely possible to be a stalwart conservative and also possess the moral backbone to stand up for democracy. The failure and complicity of these Utah Republicans was never inevitable. It was a choice that each individual made.
Utah politicians have enjoyed fighting in a culture war over the past four years, steadily adding kindling to the bonfire they now claim surprises them. In some cases, it is unclear whether they truly believed the things they said, or whether they simply chose to slide down the path of political expediency in order to advance their own careers. Perhaps they thought that pandering to the far-right side of the base or turning a blind eye to Trump's behavior would not amount to much beyond a more successful re-election campaign for them.
Whatever the reason, they were wrong. And in every case, whether or not they truly "meant it" is not the important question. The important question is what we will do to hold them accountable, now that the ugly fruits of the seeds they planted have emerged.
Chase Thomas is the Executive Director for Alliance for a Better Utah


text:
layout: post
title: Dumma diskmaskin
date: 2015-06-16
---

Diskmaskinen hoppade på mig idag. Den hade diskat klart
all disken och var sådär varm och go. Så jag skulle lägga
mig lite där och värma magen. Ni vet när man råkar ha slarvat bort sin tröja någonstans i det här jättestora huset kan det vara skönt med lite värme.

Och så biter den dumma maskinen mig i magen. Jag kanske försökte ställa mig
upp när jag var på diskmaskinens lucka. Okej, jag kanske försökte dansa lite
eftersom den där fantastiska låten från Tarzan-filmen spelades. Okej, jag
glömde bort var jag var någonstans.

Men det är banne mig inte skäl att bitas. Dumma diskmaskin.

![Noelle](/images/2015-06-10-diskmaskin.jpg)

Som ni ser blev det ett gigantiskt hål på mig. Blodet sprutade i flera timmar och det gjorde knas-ont överallt.

Eller så somnade jag efter fem minuter. Jag minns inte riktigt. Synd om mig är det i alla fall. Tur man har en pappa som kan det där med att trösta.

redpajama_set_name: RedPajamaGithub


B Newton Motor Company Ltd is an Independent dealership that is based in South Croydon. If you're the owner or employee of this business, please send us a little bit of information about your dealership and why customers should come and visit.
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text:
package medicalinfo.diseaseandcure;

import java.util.ArrayList;

public class ConsultController {
	static ConsultDB cdb = new ConsultDBPersistent();

	public static void save(Consult consult) {
		if(!MedicateController.is_medicating(consult.getTowho(), consult.getAzki()) &&
				!MedicateController.is_medicating(consult.getAzki(), consult.getTowho()) )
			try {
				throw new Exception("Doctor is not medicating thisPatient");
			} catch (Exception e) {
				// TODO Auto-generated catch block
				e.printStackTrace();
				return;
			}
		cdb.save(consult);
	}

	public static void merge(Consult consult) {
		cdb.merge(consult);
	}

	public static ArrayList<Consult> get_all_consult(String username) {
		return cdb.get_all(username);
	}

}


I wrote the other day about some crazy people I was encountering in the course of working on my Hynek book, and today I finally got a little help decoding certain people's behavior. Turns out the situation--and the people--aren't quite as crazy as they were appearing. But they're still crazy.
So, here's the deal. I'm corresponding with three people who I want to interview for my book. I will refer to them as People #1, 2 & 3, and I should note that they all know each other.
Person #1 is cool, not crazy at all, an oasis of normalcy in the UFO world.
Person #2 seems sane, but has some credibility issues as far as I'm concerned.
The whole thing started when #1 recommended that I interview #2 and #3 for the book, thinking they would have interesting insights on Dr. Hynek's work. I have made a couple attempts to interview #2, but so far we haven't been able to sync up our schedules.
I recently contacted #3 to request an interview. I was very polite. I offered to send along a sample of my writing. The response I got was very curt and yet utterly impossible to follow. It seemed hostile, but it was just vague enough that I really couldn't tell. So I followed up with another email or two, still hoping to open up a dialog.
#3 responded with a shockingly angry and incoherent letter stating that Person #2 had already told #3 all #3 needs to know about me. #3 then went on to criticize my writing (none of which #3 has actually read, to my knowledge), to criticize my book project (which I know for a fact #3 hasn't read), and to claim that I have been going around telling people that I've already interviewed #3 for the book--which is just beyond dumb--and so I should just shut up and go away.
But here's the catch: Person #3 cc'd Person #2.
Yeah, it's a lot like dealing with these guys, only add 1 to each number.
Next thing I know, Person #2 emails me and is apologizing like crazy for maybe, possibly, having said something bad about me to Person #3 (without actually telling me what that bad thing might be), and promising to arrange personally for me to get my interview with #3.
How do I know the contents of this email? Because #3 forwarded it to me moments later, with a note that said, and I quote: "...as I parse this: everybody lies!"
He said this is pretty much how Person #2 and Person #3 treat everybody.
Wow, that makes me feel better... Person #1 then said I should probably just interview them both and hope that maybe out of each interview I'll get a syllable that I can use in the book.
Yeah. Maybe. But I'm not in a huge rush.


Babar qualified from Guy's, King's & St Thomas' hospital in 2007 and has since completed his Member of the Joint Dental Faculty with Royal College of Surgeons of England. In pursuit of excellence, Babar also completed certificate training in Implantology with Warwick University and proceeded further gaining a Masters in Clinical Dentistry (Implants) with BPP University.
Babar is dedicated to providing the best care for his patients and has worked with the London Deanery and Health Education England in training younger graduates as an education supervisor.
He enjoys building a rapport with his patients therefore is able to provide the care that our patients at Augustus Road Dental Practice deserve.
Nazia qualified from Guy's, King's & St Thomas' hospital in 2008. She went on to complete her Member of the Joint Dental Faculty with Royal College of Surgeons of England and continued her development attending numerous seminars and courses.
Nazia has developed an excellent set of skills caring for her patients and is passionate about preventative dentistry and applies this to young children.
Juliana graduated in Brazil in 2002. She completed her UK registration examination in 2010 and her vocational training in 2011. Juliana has developed and fine-tuned her dentistry working in London and has been at Augustus Road Dental Practice for the last 6 years. She has recently completed her Facial Aesthetic registration and attends numerous dental courses.
Juliana enjoys cosmetic dentistry and finds it rewarding when patients with complex dental problems are able to smile again.
Keiron qualified from Kings College 2012 with a bachelor's degree in Dental Surgery having previously completed a degree in Biomolecular Science. He then completed his vocational training in Lincolnshire followed by a year as a Senior House Officer in Oral and Maxillofacial surgery at the Royal London Hospital.
Keiron has a keen interest in minimally invasive, aesthetic and cosmetic dentistry in which he has received advanced training. Keiron also has training and experience in providing anti-wrinkle treatments and facial rejuvenation using botulinum toxin and dermal fillers.
Wiola qualified with diploma from Poland with Gdansk university. She takes pride in being both thorough and gentle with therapy provided by her, as well as putting nervous patients at ease throughout their hygiene experience, believing that good communication is essential at all times. She also enjoys spending time with her patients, encouraging and motivating them to improve and achieve better oral health at home.
Lynn qualified at the Royal London Hospital in 1981. Over the years, Lynn has developed a strong bond with her patient list and particularly enjoys helping them improve their dental health and smile. Being part of a great team, working towards that goal, gives her a lot of satisfaction.
Anna joined the practice in September 2012 and qualified as a dental nurse in July 2013. She is our head nurse and is registered with the General Dental Council and has plenty of experience in dental nursing.
Mellissa has been with us since 2017 and is very friendly and good at making patients feel at ease.
Esi joined in 2017 and has been an integral member for Augustus Road Dental practice. She will make sure you are comfortable throughout your dental care.
Lisa qualified with the Diploma in Dental Nursing in 2007 and has been registered with the General Dental Council since 2008. She has good experience with all aspects of NHS and Private Dentistry including implant dentistry. Lisa has been Augustus Road Dental Practice Manager since January 2013.
Pam has been a receptionist at Augustus Road Dental Practice since 1998. Her experience at the practice for over 20 years, coupled with her friendly and approachable manner, will assist you with your appointment requirements.


Every dog owner comes in contact with poop bags and poop bag dispensers. First, it is naturally neat and nice to pick the poo of your dog. The cleanup is compulsory almost everywhere, in some cities it is only not required in designated areas.
Did you know that it is now mandatory in many municipalities in the Netherlands to have poop bags with you when you are walking the dog? The fines are hefty, as there are communities that give you a fine up to € 100 if you do not have poop bags with you while walking the dog.
Also, if your municipality has not mandated to have poop bags with you, you should still clean up the poop of your dog. Municipalities require this because dog waste does not contribute to a clean street nor street view. In addition, hygiene plays a major role. It is therefore highly recommended to have a good, solid and beautiful poop bag dispenser with poop bags with you.
A must is to look at the modern and trendy poop bag dispensers of the Italian brand United Pets. These dispensers come in many different colors and designs. Famous designers have done their best to apply modern design to your poop bag dispenser so that is becomes suddenly a real eye-catcher! They come in different sizes and, of course, can be ordered with the corresponding poop bags, which you can also choose in different colors.
You can consciously choose products that are less harmful to the environment. There are poop bags and poop bag dispensers that are 100% biodegradable! The poop bags of Becobag are even more big and strong, so highly recommended. United Pets poo bags are also completely biodegradable, so good for the environment.


A boy has escaped death after getting trapped under a car. He was chasing his friend across a street in Xinxiang, central China's Henan Province when he was hit by the vehicle. Passersby rushed to help him, lifting the car to free him. He was sent to the hospital where he is in a stable condition.


text:
Home/UK
Britain will introduce tougher jail sentences for convicted terrorists and will end early release as part of a series of…
More than 3 million adults in Uk were victims of child sexual abuse, new figures show
More than 3 million adults in England and Wales were victims of child sexual abuse, new figures show, prompting fresh concerns about under-reporting…
Air pollution is set to cause 160,000 deaths in UK over the next decade
Air pollution will cause 160,000 fatal strokes and heart attacks in the next decade unless the Government acts to clean…
UK issues extradition request for American woman charged in death of British teen
Authorities in the United Kingdom have sent the US State Department an extradition request for Anne Sacoolas, the wife of…
Boris Johnson to tell Von Der Leyen trade deal must be done without extension
Boris Johnson will stress the importance of the UK and EU reaching a trade deal by the end of the…
Government stands down no-deal Brexit planning despite PM election pledge
Britain's emergency preparations for a no-deal Brexit have been halted "with immediate effect", as Prime Minister Boris Johnson's deal to…
Exclusive: China halts UK stock link over political tensions
China has temporarily blocked planned cross-border listings between the Shanghai and London stock exchanges because of political tensions with Britain,…
UK to raise concerns with Cyprus after British teen is found guilty of false rape claim
The UK is "seriously concerned about the fair trial guarantees" in the case of a British teenager found guilty of…


Corfu, WashingtonPhotos, maps and news from Corfu, Washington.Updated March 18, 2018.
Corfu is an unincorporated community in Grant County, in the U.S. state of Washington.
Ghost town of Corfu Grant County Washington. .
Ghost town of Corfu Grant County Washington. Corfu School.
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Ghost town of Corfu Grant County Washington. Home · Grant County.
Map of Corfu, WA, Washington. Corfu, Washington WA Souvenir Shirt.
Ghost Towns of Grant County Washington. Grant County.
Map of Corfu, WA, Washington. Map of Corfu Washington WA.
Moses Lake | The Long Hunt. Weeping Willow and Loansome Hart left photographs of themselves inside a banjo ukulele, as a.


text:
GST Bill
Goods And Services Tax Bill
GST Bill passed in Himachal Pradesh
The Bill has multiple provisons like recovery of arrears of tax using various modes including detaining and sale of goods, movable and immovable property of defaulting taxable person and powers of inspection, search, seizure and arrest to the officers.TNN | May 28, 2017, 09:23 IST
SHIMLA: Himachal Pradesh Assembly in its special session held on Saturday unanimously passed the Himachal Pradesh Goods and Services Tax Bill, 2017. The Bill has multiple provisons like recovery of arrears of tax using various modes including detaining and sale of goods, movable and immovable property of defaulting taxable person and powers of inspection, search, seizure and arrest to the officers.
While presenting the bill in the assembly, chief minister Virbhadra Singh said GST will bring down the cost of goods and services as there will be no cascading effects of taxes. He added that GST is expected to increase revenue by widening the tax base and improving the taxpayer compliance. 7% items are such on which no taxes would be levied, 14% items would be in the lowest bracket of 5% tax, 17% items will have 12% tax, 43% items will have 18% tax, and 19% items, which are generally not used by people will have 28% tax.
"It would be a dual GST with the Centre (CGST) and states (SGST) simultaneously levying tax on a common tax base," he added.
Leader of opposition Prem Kumar Dhumal said earlier traders and businessmen had to pay various taxes but with the implementation of GST from July 1, consumer, trader and middleman would have to pay single tax. He said 150 countries that have adopted GST have witnessed a growth in their GDP by 1.5% to 2% and added that in India 1200 items under GST have already been decided to levy tax. Dhumal said GST would be consumer friendly and in the interest of people of Himachal Pradesh, which is a consumer state.
10 things to know about the new GST tax structure
Tags : Industry, GST Bill, Himachal Pradesh, Goods And Services Tax Bill, Goods and Services Tax
Resolving Amrapali, Unitech and Jaypee will change discourse: Housing Minister
What real estate industry expects from Budget 2019?


text:
The Rolls-Royce Trent 500 is a high-bypass turbofan produced by Rolls-Royce to power the larger A340-500/600 variants.

It was selected in June 1997, first ran in May 1999, first flew in June 2000, and achieved certification on 15 December 2000.
It entered service in July 2002 and 524 engines were delivered on-wing until the A340 production ended in 2011.

Keeping the three spool architecture of the Trent family, it has the Trent 700's 2.47 m (97.5 in) fan and a Trent 800 core scaled down. It produces up to 275 kN (61,900 lbf) of thrust at take-off and has a bypass ratio up to 8.5:1 in cruise.

Development
In 1995, Airbus began considering an engine for two new long-range derivatives of its four-engined A340, the A340-500/600. The existing A340-200/300 was powered by CFM International CFM56 engines. However, the CFM56 was at the limit of its development capability, and would be unable to power the new A340-500/-600. In April 1996, Airbus signed an agreement with GE Aviation to develop a suitable engine, but decided not to proceed when GE demanded an exclusivity deal on the A340.

Certification was applied for on 9 February 1998.
The Trent 500 first ran in May 1999.
By July 1999, Rolls-Royce had secured $5 billion worth of Trent 500 orders.
Flight testing began in late June 2000 on a modified A340 testbed. By July 2000, the test program had amassed 1,750h and 2,00 cycles, and aimed for 15,000h and 4,000-5,000 cycles before introduction. It achieved certification on 15 December 2000.

It entered service on the A340-600 with Virgin Atlantic in July 2002 and on the ultra-long range A340-500 with Emirates in December 2003. Air Canada had been expected to be the launch customer for the A340-500 in May 2003, but just before this on 1 April 2003 the airline filed for bankruptcy protection which resulted in delivery of its two A340-500s being delayed. This allowed Emirates to be the first airline to operate the type. After production of the Airbus A340 ended in 2011, a total of 131 A340-500/-600 have been delivered with 524 Trent 500 engines altogether; Lufthansa is the largest operator, with 24 delivered A340-600.

Design
The Trent 500 is a high bypass turbofan with three spools: the fan is powered by a 5 stage Low Pressure turbine (nominal speed: 3,900 RPM), the Intermediate pressure spool has an 8-stage axial compressor (9,100 RPM) and the High Pressure spool has an 6-stage axial compressor (13,300 RPM), both driven by a single turbine stage. It has an annular combustor and is equipped with an Electronic Engine Control System.

It is flat rated at ISA + 15°C for 248.1-275.3 kN (55,780-61,902 lbf) net thrust at take-off and has an 8.5:1 bypass ratio in cruise.

The Trent 500 is essentially a scaled Trent 800, with a 2.47 m (97.5 in) fan with 26 unswept blades like the Trent 700. The IP and HP compressors and scaled-down by 20% from the Trent 892, while the turbines are scaled-down by 90% and are made of single crystal CMSX-4 alloy with thermal barrier coatings. Fuel burn is 1% lower because of 3D aerodynamics. It was tested up to  to establish limits.

The Trent 500 powers the A340-500/600. It was certificated at  thrust, but derated to  as the Trent 553 to power the A340-500, and to  as the Trent 556 for the A340-600 and A340-500HGW. However, a  version is installed in the A340-600HGW (High Gross Weight), a higher-performance version of the A340-600. The Trent 500 has the same wide chord fan as the Trent 700, together with a core scaled from the Trent 800.

Applications
Airbus A340

Specifications

See also

References

External links

High-bypass turbofan engines
Trent 500
1990s turbofan engines

redpajama_set_name: RedPajamaWikipedia


text:
HomeShopField TripsThe Human Body
Explore inside the body through a 360/interactive documentary video.
Bring 10 realistic, anatomical 4D holograms to life right at home.
Track a global pandemic on a Google Earth Voyage.
Complete interactive VARK workbooks designed to help you remember what you learn.
Understand foundational first principles through educational slideshows and worksheets.
Complete quests to earn achievements, badges, and points.
The Human Body quantity
Category:Field Trips Tag:Science
Calling all future doctors! Put on your white coat because we're going inside the human to learn all about anatomy and medicine with an interactive, educational virtual field trip. We'll start off with a video journey inside our micro mobile where you'll go inside a patient to fix a few problems.
Afterwards, we'll convert your room into a doctors office to explore the human body piece by piece. We'll break down the Abdomen, put a brain in your hands and truly understand our body with realistic 4D holograms like never before.
That's not all though! We'll embark on a Google Earth Voyage through the Bubonic plague to discover the history of the world worst pandemic. All with guided tours and critical thinking questions to help you learn and understand.
Practice what you learned with interactive VARK workbooks where you'll play fun learning games, master your memory, and improve your vocabulary. If you're a teacher, plug and play our included interactive classroom curriculum.
Explorers are motivated to complete quests to collect badges and earn gold to redeem a ZooCard, other souvenirs or save for their next virtual field trip.
Perfect for grades K-5 and COVID-19 homeschoolers.
205 reviews for The Human Body
– July 19, 2021 Amanda U (verified owner)
– July 31, 2021 Danielle O. (verified owner)
– August 6, 2021 Library Princess (verified owner)
– August 8, 2021 Gretchen L. (verified owner)
– August 11, 2021 Matt K. (verified owner)
– August 30, 2021 Kate O. (verified owner)
– September 1, 2021 Anna (verified owner)
– September 3, 2021 Angela R. (verified owner)
– September 4, 2021 Specky Techy (verified owner)
– September 11, 2021 Janel Reyneke (verified owner)
– September 15, 2021 Kate C. (verified owner)
– September 18, 2021 Janine S. (verified owner)
– September 18, 2021 Nina F. (verified owner)
– September 23, 2021 Yi We (verified owner)
– September 24, 2021 Kevin L. (verified owner)
– September 29, 2021 Maggie S. (verified owner)
– October 6, 2021 Lana R. (verified owner)
– October 7, 2021 Specky Techy (verified owner)
– October 7, 2021 Jessica Fletcher (verified owner)
– October 7, 2021 Lauren R. (verified owner)
– October 8, 2021 Angela S. (verified owner)
– October 15, 2021 Specky Techy (verified owner)
– November 3, 2021 Patti S. (verified owner)
– November 4, 2021 Anna (verified owner)
Some of the slides were too hard for my second graders, but it was easy to just delete slides I didn't need and assign the ones that were relevant.
– November 12, 2021 Kate D. (verified owner)
– November 17, 2021 Anthony Z. (verified owner)
– November 26, 2021 Andrea DePiero (verified owner)
Our students LOVED these! They were easy to add to google classroom for our remote learners and were great practice for our students to use both their Chromebook skills and team working social skills.
– November 28, 2021 Kate A. (verified owner)
– November 28, 2021 Andy L. (verified owner)
– November 28, 2021 Lani H. (verified owner)
– December 3, 2021 Lauren R. (verified owner)
Love these field trips! Each virtual trip contains so many helpful resources. Thanks for providing activities that can be differentiated across different grade levels.
– December 5, 2021 Specky Techy (verified owner)
– December 14, 2021 Kara G (verified owner)
This is an incredibly well-done resource! It\\\'s very engaging and contains a lot of interesting facts and video links. I wish I could edit where there are typos, though, as it really isn\\\'t feasible to email every time one comes to my attention. 🙂 This is a fantastic idea and valuable resource!
– December 17, 2021 Ping (verified owner)
– December 24, 2021 Kate C. (verified owner)
My students loved this resource! There was so much in it, we didn\\\'t get a chance to finish it. I will definitely start these activities earlier next November.
– December 27, 2021 Andrea DePiero (verified owner)
– December 28, 2021 Andy L. (verified owner)
– December 28, 2021 Gretchen L. (verified owner)
I love the variety of field trips we are able to take with students in this bundle. I can find a field trip to match almost any topic I\\\'m teaching!
– January 2, 2022 Inspired Apple (verified owner)
– January 4, 2022 Lani H. (verified owner)
– January 7, 2022 Kate B. (verified owner)
– January 9, 2022 Tara C. (verified owner)
– January 11, 2022 Amanda U (verified owner)
– January 13, 2022 Lana R. (verified owner)
– January 14, 2022 Nina Y. (verified owner)
– January 18, 2022 Kate B. (verified owner)
– January 18, 2022 Roselle T. (verified owner)
– January 23, 2022 Amy V. (verified owner)
– January 26, 2022 Nina A. (verified owner)
– January 26, 2022 Mrs.TTT (verified owner)
– January 30, 2022 Jessica Fletcher (verified owner)
These have a lot of activities and information in them. I didn\\\'t realize they are so involved. That is a good thing though. I am thoroughly pleased with them.
– January 30, 2022 Natalie W. (verified owner)
– January 31, 2022 Patrick M. (verified owner)
– February 9, 2022 Loretta E. (verified owner)
– February 11, 2022 Angela R. (verified owner)
– February 15, 2022 Library Princess (verified owner)
– February 15, 2022 Kara G (verified owner)
– February 15, 2022 Mrs.TTT (verified owner)
– February 19, 2022 Heather S. (verified owner)
– February 21, 2022 Kelsey S. (verified owner)
– February 21, 2022 Sachiko B. (verified owner)
– February 22, 2022 Gretchen L. (verified owner)
– February 23, 2022 Tracy C. (verified owner)
– March 4, 2022 Violet M. (verified owner)
– March 4, 2022 Lani H. (verified owner)
Exactly what I needed for June. We took many breaks and this was perfect. Also need to share that when I had an issue and emailed her, she QUICKLY responded and helped me out. Highly recommend!!!!!
– March 6, 2022 Crystal S. (verified owner)
– March 7, 2022 Helena D. (verified owner)
I loved this! We had so much fun going through each slide and my students were so sad when it was over! I cannot wait to use this resource again!
– March 9, 2022 Kara G (verified owner)
– March 12, 2022 Natalie W. (verified owner)
– March 12, 2022 Kristin B. (verified owner)
– March 16, 2022 Kate D. (verified owner)
– March 16, 2022 Anthony Z. (verified owner)
– March 18, 2022 Andrea DePiero (verified owner)
– March 25, 2022 Loretta E. (verified owner)
– March 29, 2022 Jessica Fletcher (verified owner)
– March 30, 2022 Anna (verified owner)
– April 1, 2022 Meghana R. (verified owner)
– April 2, 2022 Asheley W. (verified owner)
– April 2, 2022 Jessica Fletcher (verified owner)
– April 5, 2022 Anna Tramel (verified owner)
– April 5, 2022 Kelsey S. (verified owner)
– April 9, 2022 Kara G (verified owner)
This was a fun activity to do right before Thanksgiving Break
– April 10, 2022 Malinda (verified owner)
During distance education this provided a great motivating way for me to continue our Fun Friday virtually. The students always worked hard to complete all their assignments and get them turned in because they wanted to earn their \\\"ticket\\\" for the field trip.
– April 13, 2022 Inspired Apple (verified owner)
– April 14, 2022 L\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'erin D. (verified owner)
– April 18, 2022 Debra L. (verified owner)
– April 25, 2022 Library Princess (verified owner)
Do you know how much time you\'ve saved me??? I love doing virtual field trips with my kids and have been building out all the resources myself. This is a PERFECT way to save time and assign a great activity for my kids. Thanks!!
– April 27, 2022 Lauren R. (verified owner)
– April 27, 2022 Stephanie N. (verified owner)
Students enjoyed using these resources
HOLOGRAMS!
– April 27, 2022 Angela R. (verified owner)
My students loved this resource! There was so much in it, we didn\\\\\\\'t get a chance to finish it. I will definitely start these activities earlier next November.
– April 27, 2022 Sallie S. (verified owner)
– April 27, 2022 Violet M. (verified owner)
During distance education this provided a great motivating way for me to continue our Fun Friday virtually. The students always worked hard to complete all their assignments and get them turned in because they wanted to earn their \\\\\\\"ticket\\\\\\\" for the field trip.
Can\\\\\\\'t wait to use it next year as a lot of our science that we\\\\\\\'ve already done fits these and I can use more.
These Virtual Field trips are a life saver! My students can not wait for the next trip. The lessons are wonderful. Very informational.
– April 27, 2022 Ping (verified owner)
Great resource, was able to use it effectively in my special education classroom.
These are my absolute FAVORITE resources! The kids love them, they are easy to use, some parts are editable, and I was able to easily add audio to meet the accommodations necessary for some of my students!
My students loved this. It was engaging and went well with our curriculum. Can\\\\\\\'t wait to use more of them this coming year. Thank you!
While there were some great ideas and videos, the majority of this activity was too difficult for my second graders.
– April 27, 2022 Natalie W. (verified owner)
Perhaps it is meant only for K and 1, but it only gave very few usable passages for my second grader. I was very disappointed because of the cost of the bundle. It would have been beneficial to have additional previews before purchase.
– April 27, 2022 Kevin L. (verified owner)
– April 27, 2022 Danielle O. (verified owner)
– April 27, 2022 Kevin D. (verified owner)
Wonderful and engaging resource!
– April 27, 2022 Anna (verified owner)
– April 27, 2022 Tracy C. (verified owner)
I LOVE these digital field trips! They are such a cool way for students (and me) to learn about and \\\\\\\"visit\\\\\\\" new places! They are lengthy, but I have been using them as early finisher work and it has been great.
I look forward to all of the new releases and plan to use them often in the upcoming years. Thanks!
We had lots of fun in class completing this. My students were very engaged and have been loving the virtual field trips.
– April 27, 2022 Angela S. (verified owner)
– April 27, 2022 Glenwood Elementary (verified owner)
This is an extremely fun and engaging activity. I did it over several days with my fourth graders. They were able to do the activities independently. If you purchase for younger students, you will need to guide them. The videos are extremely engaging and informational!
So far I have used two of the workbooks and they have worked out well.
– April 27, 2022 Kate O. (verified owner)


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November 29, 2017 - ORLANDO, Florida – Hurricane Junior Golf Tour (HJGT) is pleased to announce new division ambassadors – Tiger Woods, Justin Timberlake, Justin Rose, Will Smith and Ernie Els – each representing a different division within the Hurricane Junior Golf Tour as it furthers its mission to grow the game of golf amongst juniors.
Hurricane Junior Golf Tour's largest age divisions will now include: the Tiger Woods Division (Boys 16-18), the Will Smith Division (Boys 14-15), the Ernie Els Division (Boys 11-13), the Justin Timberlake Division (Girls 14-18) and the Justin Rose Division (Girls Under 13).
Within each division, two champions will be crowned each year; Player of the Year, awarded to the player that accumulates the most points throughout the season within their division, and also the winner of the Hurricane World Championship, hosted in Orlando in August. These two winners within each division will be invited to sit down together with their respective ambassador for an intimate 30-minute sit-down. The winners will be flown to a city of the ambassador's choice for their meeting.
"Growing the game of golf is good for everyone, and if we can inspire these kids to chase their goals – even better," said Justin Rose.
Earlier this year, Nexus Luxury Collection partnered with the Hurricane Junior Golf Tour, acquiring a stake in the grass roots golf tour.
Founded in 2007 by Mario Conte, the Hurricane Tour has become the largest junior golf tour in the United States, hosting over 275 tournaments each year across 32 different states. To date, more than 30,000 boys and girls have competed in a Hurricane Tour event and over 3,500 golfers have made it to the collegiate golf ranks since its inception.


Welcome to the German Language School Wellington.
The German Language School Wellington is a parent initiative that was founded with the aim of teaching German speaking children aged 5 years and above German conversation, reading, writing, and grammar. We also want to foster friendships and build a community with other German speaking children and families, and to have fun learning about and celebrating cultural events together.
We currently employ 3 teachers (with German as their mother tongue) who teach 5-6 classes. We have small classes with a maximum of 10 children. As a parent initiative, we keep costs low at ca $9 per week (ca $90 per term) depending on the number of children attending. New children of any age are welcome and get to have one free trial lesson to help decide whether they want to become a member of the group.
We look forward to hearing from you - you can send us a message here .
Please note that we are not resourced to offer "German as a foreign language" classes to beginners. Our children usually grow up in bi- or even trilingual families, where mum and/or dad is from a German speaking country, and they have German as one of their native languages.
We offer a German immersion afternoon to the families at our German school, with children having the rare opportunity to speak and listen to only German while playing together. At Karori West Normal School, we have access to a large outdoor area with a variety of play and sports areas. We are also able to access the school's spacious staff room to chat over a cup of tea or coffee, play games or read a book. Our small German library with German books, CDs and DVDs is located in the staff room too and all members of our language school are very welcome to use it.


text:
package com.amazonaws.services.elasticmapreduce.model.transform;

import java.util.List;
import javax.annotation.Generated;

import com.amazonaws.SdkClientException;
import com.amazonaws.services.elasticmapreduce.model.*;

import com.amazonaws.protocol.*;
import com.amazonaws.annotation.SdkInternalApi;

/**
 * StudioMarshaller
 */
@Generated("com.amazonaws:aws-java-sdk-code-generator")
@SdkInternalApi
public class StudioMarshaller {

    private static final MarshallingInfo<String> STUDIOID_BINDING = MarshallingInfo.builder(MarshallingType.STRING).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("StudioId").build();
    private static final MarshallingInfo<String> STUDIOARN_BINDING = MarshallingInfo.builder(MarshallingType.STRING).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("StudioArn").build();
    private static final MarshallingInfo<String> NAME_BINDING = MarshallingInfo.builder(MarshallingType.STRING).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("Name").build();
    private static final MarshallingInfo<String> DESCRIPTION_BINDING = MarshallingInfo.builder(MarshallingType.STRING)
            .marshallLocation(MarshallLocation.PAYLOAD).marshallLocationName("Description").build();
    private static final MarshallingInfo<String> AUTHMODE_BINDING = MarshallingInfo.builder(MarshallingType.STRING).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("AuthMode").build();
    private static final MarshallingInfo<String> VPCID_BINDING = MarshallingInfo.builder(MarshallingType.STRING).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("VpcId").build();
    private static final MarshallingInfo<List> SUBNETIDS_BINDING = MarshallingInfo.builder(MarshallingType.LIST).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("SubnetIds").build();
    private static final MarshallingInfo<String> SERVICEROLE_BINDING = MarshallingInfo.builder(MarshallingType.STRING)
            .marshallLocation(MarshallLocation.PAYLOAD).marshallLocationName("ServiceRole").build();
    private static final MarshallingInfo<String> USERROLE_BINDING = MarshallingInfo.builder(MarshallingType.STRING).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("UserRole").build();
    private static final MarshallingInfo<String> WORKSPACESECURITYGROUPID_BINDING = MarshallingInfo.builder(MarshallingType.STRING)
            .marshallLocation(MarshallLocation.PAYLOAD).marshallLocationName("WorkspaceSecurityGroupId").build();
    private static final MarshallingInfo<String> ENGINESECURITYGROUPID_BINDING = MarshallingInfo.builder(MarshallingType.STRING)
            .marshallLocation(MarshallLocation.PAYLOAD).marshallLocationName("EngineSecurityGroupId").build();
    private static final MarshallingInfo<String> URL_BINDING = MarshallingInfo.builder(MarshallingType.STRING).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("Url").build();
    private static final MarshallingInfo<java.util.Date> CREATIONTIME_BINDING = MarshallingInfo.builder(MarshallingType.DATE)
            .marshallLocation(MarshallLocation.PAYLOAD).marshallLocationName("CreationTime").timestampFormat("unixTimestamp").build();
    private static final MarshallingInfo<String> DEFAULTS3LOCATION_BINDING = MarshallingInfo.builder(MarshallingType.STRING)
            .marshallLocation(MarshallLocation.PAYLOAD).marshallLocationName("DefaultS3Location").build();
    private static final MarshallingInfo<String> IDPAUTHURL_BINDING = MarshallingInfo.builder(MarshallingType.STRING)
            .marshallLocation(MarshallLocation.PAYLOAD).marshallLocationName("IdpAuthUrl").build();
    private static final MarshallingInfo<String> IDPRELAYSTATEPARAMETERNAME_BINDING = MarshallingInfo.builder(MarshallingType.STRING)
            .marshallLocation(MarshallLocation.PAYLOAD).marshallLocationName("IdpRelayStateParameterName").build();
    private static final MarshallingInfo<List> TAGS_BINDING = MarshallingInfo.builder(MarshallingType.LIST).marshallLocation(MarshallLocation.PAYLOAD)
            .marshallLocationName("Tags").build();

    private static final StudioMarshaller instance = new StudioMarshaller();

    public static StudioMarshaller getInstance() {
        return instance;
    }

    /**
     * Marshall the given parameter object.
     */
    public void marshall(Studio studio, ProtocolMarshaller protocolMarshaller) {

        if (studio == null) {
            throw new SdkClientException("Invalid argument passed to marshall(...)");
        }

        try {
            protocolMarshaller.marshall(studio.getStudioId(), STUDIOID_BINDING);
            protocolMarshaller.marshall(studio.getStudioArn(), STUDIOARN_BINDING);
            protocolMarshaller.marshall(studio.getName(), NAME_BINDING);
            protocolMarshaller.marshall(studio.getDescription(), DESCRIPTION_BINDING);
            protocolMarshaller.marshall(studio.getAuthMode(), AUTHMODE_BINDING);
            protocolMarshaller.marshall(studio.getVpcId(), VPCID_BINDING);
            protocolMarshaller.marshall(studio.getSubnetIds(), SUBNETIDS_BINDING);
            protocolMarshaller.marshall(studio.getServiceRole(), SERVICEROLE_BINDING);
            protocolMarshaller.marshall(studio.getUserRole(), USERROLE_BINDING);
            protocolMarshaller.marshall(studio.getWorkspaceSecurityGroupId(), WORKSPACESECURITYGROUPID_BINDING);
            protocolMarshaller.marshall(studio.getEngineSecurityGroupId(), ENGINESECURITYGROUPID_BINDING);
            protocolMarshaller.marshall(studio.getUrl(), URL_BINDING);
            protocolMarshaller.marshall(studio.getCreationTime(), CREATIONTIME_BINDING);
            protocolMarshaller.marshall(studio.getDefaultS3Location(), DEFAULTS3LOCATION_BINDING);
            protocolMarshaller.marshall(studio.getIdpAuthUrl(), IDPAUTHURL_BINDING);
            protocolMarshaller.marshall(studio.getIdpRelayStateParameterName(), IDPRELAYSTATEPARAMETERNAME_BINDING);
            protocolMarshaller.marshall(studio.getTags(), TAGS_BINDING);
        } catch (Exception e) {
            throw new SdkClientException("Unable to marshall request to JSON: " + e.getMessage(), e);
        }
    }

}