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myEnglish launches in Bengaluru and Mumbai
Posted in English, myEnglish and tagged Bengaluru, British Council, British Council India, Communication, English courses, launch, Mumbai, myEnglish, technology on January 15, 2016 by Neenaz Ichaporia.
Students of English in Mumbai and Bengaluru now have a reason to celebrate. The British Council marked the launch of its pioneering blended learning programme in these cities on 12 January, 2016. myEnglish combines the latest education technology and student-centred classroom instruction to improve students' language skills, and more. The courses also foster essential 21st century skills such as time management, independent learning and critical thinking. While the courses are now available to more students across two new cities, they have been running successfully in Pune since May 2015.
The formal launch event in Bengaluru was well-attended as several eminent panellists joined members of the press and public for a discussion on 'Better English, Better Opportunities'. The panel comprised experts from the world of business, education and technology; including Arvind Katageri (Senior Manager, Centre for Behavioural Excellence – Talent Transformation, Wipro), Ashwani Sharma (Country Head, University Relations, Google India Pvt Ltd), Lalitha Murthy (Consultant, Business English, Tata Consultancy Services) and Nirupa Fernandez (Assistant Director, English, British Council).
The panellists discuss 'Better English, Better Opportunities' at the myEnglish launch event in Bengaluru
A lively dialogue ensued as the panellists discussed the role of English in the world of business. Lalitha Murthy from Tata Consultancy Services pointed out that while many new recruits may be confident about their English skills, what they may lack is the communicative competence required in the business world. Another topic discussed was the role played by technology in education. As Ashwini Sharma from Google pointed out, "Even a pen is technology" and in the debate that followed the panellists concluded that technology had always been present in education and that teachers have a responsibility to keep up with developments.
The launch was also attended by two myEnglish students, Ramchandra Kulkarni and Vishal Chandegave, who spoke eloquently and positively about their experiences on the course and about how it has helped them be more confident in their professional and daily lives. Read more about their experiences in The Times of India and the Deccan Herald.
The myEnglish launch event in Bangalore was accompanied by a simultaneous press release in Mumbai and has generated a lot of interest among the press in both cities, with coverage in major publications including the Times of India, the New Indian Express, the Deccan Chronicle and the Deccan Herald. Several news websites and regional publications also covered the event.
For more information on myEnglish, please visit our course page.
If you want to register for a course, please leave your details here and we will get back to you.
Kathryn Harkup: the secret poisons of Agatha Christie
Posted in Arts and tagged A is for Arsenic: the Poisons of Agatha Christie; books, Agatha Chrsitie, British Council, Crime, Crime Writers Festival, Kathryn Harkup, New Delhi, Thriller on January 8, 2016 by Debesh Banerjee.
Agatha Christie had most certainly one poison for every occasion. As her tally of "killings" in her novels reflects that a total of 100 killings out of 300 were committed by poison. As a former volunteer nurse in World War 1, Christie had gained extensive knowledge of her chemicals. No wonder she used them to good effect to eliminate her characters.
In her debut non-fiction book , A is for Arsenic: The Poisons of Agatha Christie chemist Dr Kathryn Harkup reveals her passion and respect for the work of Agatha Christie.
In this blog post, Harkup shares some interesting trivia & lesser-known facts about Christie and her use of poison through her fiction series.
Christie used more poisons and more often than any other crime writer. Her toxic tally is over 30 different killer compounds. She killed over 300 characters, over 100 of them by poison. She consistently displays an impressively high degree of accuracy in her use of poisons.
Kathryn Harkup, author of "A is for Arsenic: The Poisons of Agatha Christie"
Christie trained as an Apothecaries' Assistant during WWI which made her very knowledgeable in chemistry as well as dangerous drugs and different prescriptions that were available. Her first novel, The Mysterious Affair at Styles, written when she was working in a hospital dispensary, used three drugs to kill the victim (bromide powders, a narcotic and strychnine). She was complimented on her accuracy by a reviewer in The Pharmaceutical Journal, a review she was said to cherish above all others.
Her novel The Pale Horse used thallium, a very unusual poison. The plot was similar to some aspects of a real-life poisoning case, Graham Young who poisoned several of his work colleagues with thallium, and it was suggested Christie may have inspired him but he always denied it. But the novel may have saved two lives because the accurate descriptions of thallium poisoning symptoms alerted doctors to the true cause of a young girl's mysterious illness.
Christie often used real-life murder cases as inspiration for her plots. Aspects of the Dr Crippen poisoning case appear in Ordeal by Innocence. The arsenic in the cake in After the Funeral is similar to the Marie LaFarge case. The suspected arsenic poisoning in Murder is Easy is very similar to the Armstrong case.
*This post was contributed by Dr Kathryn Harkup who will present her session at the Crime Writers Festival at the Apeejay Kolkata Literary Festival on 15 January & on the 17 Jan at the Oxford Books store, Connaught Place, New Delhi.


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Will Houston and Toronto give the NBA Finals a fresh look?
"He's alright but he's not real!"
In this case, they're alright but they're not real. Right?
On Jay Z's Do It Again from Vol. 3… Life and Times of S. Carter, he wasn't taking a shot at the Houston Rockets or Toronto Raptors but this lyric applies to both of these teams based on their track record especially in the playoffs.
The Rockets are an offensive force, which has even given Golden State problems this season. James Harden is extremely hard to contain in Mike D'Antoni's offense and Houston won the season series, 2-1. Plus, Chris Paul hasn't shown any signs of slowing down and is thriving alongside Harden in the Rockets' 3-point heavy game plan.
Clint Capela is the blueprint for how to finish a pick-and-roll and role players such as Eric Gordon, Ryan Anderson and Trevor Ariza are enjoying life as a spot-up shooter. On the defensive end along with Ariza, Luc Mbah a Moute and PJ Tucker are reliable 3-and-D players.
Then the Rockets have this stellar winning percentage when Harden, Paul and Capela all play.
In the opposing conference, the Raptors are on pace to possibly prevent LeBron James from an eighth straight Finals' appearance. Dwane Casey and staff have incorporated a better offense that has Toronto playing a more modernized brand of basketball.
Leading scorer DeMar DeRozan is playing a more analytic friendly game with less isolation for mid-range jumpers but this is making him less unique as an offensive player to the viewing audience even though sacrificing for a greater goal can't be held against him. Backcourt running mate Kyle Lowry is still handling his business even though his scoring average is down from last season.
And the bench is the best in the association with C.J. Miles, Fred Van Vleet, Pascal Siakam, Delon Wright, Norman Powell and Jakob Poeltl giving opposing second units "that work."
Toronto and Houston currently have the best records in the East and West, respectively, and will probably finish in that position since Golden State and Boston are having some issues with health.
But like Lupe stated on the Intro of his debut album Lupe Fiasco's Food & Liquor, "I think the world and everything in it is made up of a mix of two things. You got your good, y'know, and your bad. You got your food, and your liquor."
While this observation applies to DeRozan and Lowry collectively in the postseason, the same can be said about Harden and Paul individually.
Since LeBron returned to The Land for the 2014-15 season, the Raptors haven't been impressive when the games matter the most. The first year they were swept by the Wizards then during the next two playoff series against Cleveland, the Raptors posed almost no threat to the Cavaliers and, at times, DeRozan and Lowry had shooting percentages colder than Toronto during the 2016 All-Star Game.
But this year should be different right? These aren't the same-old Raptors. LeBron and Kyrie Irving are on different teams and their supporting casts have their own set of questions to answer. However, when games get tight and adjustments are made will DeRozan and Lowry fall back into old habits, and when rotations shorten, will the cast of characters on the Raptors' bench be as impactful?
Before Paul arrived in Houston, his tenure with the Clippers had been marred with injuries and exits from the playoffs prior to the conference finals. In Paul's nine playoff appearances, the point guard, who is sometimes rated higher than he should be, has never participated in the West Finals.
Contrary to Paul, Harden has been to the West Finals and Finals but his playoff performances haven't been all that memorable. First in the Finals with Oklahoma City, Harden, who deserved a pass because he was young, struggled mightily against Miami then last season against San Antonio, the runner-up in the MVP voting just accepted defeat with the game still in reach.
Tony Kornheiser and Michael Wilbon summed up the doubts about Harden in the postseason with this phrase on PTI: The last time we saw Harden in the playoffs he was on the mat reaching for his mouthpiece.
What a metaphor for the ages!
Then D'Antoni has shown time and time again the inability to adjust in the playoffs which probably led to Harden impersonating Mike Tyson last season. Paul, if healthy, has the capability of preventing Harden from reliving this but how will D'Antoni adjust the offense, which appears to be replaying on a loop at times, when Golden State makes its defensive adjustment?
So many intriguing questions surround the 2018 playoffs, and that is always a plus, but Harden had one answer for The Undefeated along with the pessimists back in January.
"We're for real, for real. We are for real as it can get," said the soon-to-be-crowned 2018 MVP.
The Raptors and Rockets are definitely better than alright but are they real?
chris paulcleveland cavaliersdemar derozangolden state warriorshouston rocketsjames hardenjay-zkyle lowrylebron jameslupe fiascomike d'antoninbanba playoffstoronto raptors
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Jim Breiner is director of the Center for Digital Journalism launched in partnership with the University of Guadalajara, in Mexico, and the International Center for Journalists.
He has been a business newspaper reporter, editor and publisher for more than 30 years and draws on this experience in his journalism training.
He is fluent in Spanish and has done newsroom seminars on leadership, business journalism and investigative journalism in Bolivia and Peru. He has a special background and interest in newsroom leadership training.
Most recently he was the editorial consultant on the launch of Crain's Manchester Business, a new business weekly in England, where he interviewed, hired and trained the editorial staff.
He also is fluent in Italian and proficient in French.
On Dec. 17, 2007, Crain Communications launched the first business weekly in Western Europe. This is part of the editorial team that produced the 32-page edition of Crain's Manchester Business that quickly sold out on newsstands. The website was launched at the same time.
My job was to interview, hire and train the editorial staff for this weekly business newspaper, produce a 24-page prototype and launch the first edition, all in about 15 weeks.
Crain's already has four similar publications in the States -- Chicago, New York, Cleveland and Detroit. It also has other specialized business publications in the UK and Germany for insurance, plastics, urethane and automobiles.
A weekly business journal focused on one city is a new concept in the UK, indeed in Western Europe, although it is in every major city in the US.
More than 15,000 copies are being mailed each week to a rotating list of C-level executives, professionals and business owners.
The effort has attracted a lot of attention, since news media are consolidating in Great Britain, just as in the US, and few are launching new print vehicles. The Financial Times weighed in with a piece on regional business media. It has been quite well received so far by local communications professionals.
The UK version of Editor and Publisher published an extensive piece as well.
We were posting a good dozen web stories a day to keep the pressure on the Manchester Evening News, the principal daily in the region.


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Štěpánovský potok pramení u osady Štěpánov u Starého Města v podhůří Králického Sněžníku ve výšce asi 730 m n. m. Protéká osadou Štěpánov a teče dále k jihovýchodu údolím s občasnými lesíky. Nakonec podtéká železnici a dnes teče podél k ní téměř k jihu a nakonec se zprava vlévá do říčky Krupá (což je přítok Moravy) poblíž železniční stanice Chrastice v nadmořské výšce asi 490 m. Délka toku činí 4,3 km.

Odkazy

Poznámky

Reference

Potoky v Králickém Sněžníku
Potoky v Hanušovické vrchovině
Potoky v okrese Šumperk
Povodí Krupé

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BETHANY MOLLENKOF
Abortion in Mississippi for New York Times Magazine
VSCO x Adobe
"Turn off the Sunshine" for The New York Times
Film stills from "Hingakawa: Forgiveness is a Choice" for Starbucks
Hingakawa tells the story of a coffee co-op, more than 550 women strong, located in the mountainous region of the Gakenke district in Rwanda. Each year, the women bring the coffee they've grown to the co-op to be sorted, dried and then sold. As a group, they make business decisions, negotiate for the best prices and support each other. At Hingakawa, they know that they are strongest together.
Robert Chelsea for The Boston Globe
Robert Chelsea could be the first African-American face transplant recipient, and at 68, also the oldest. Chelsea was injured in 2013 when a drunk driver hit his stopped car, which exploded into flames, causing him to be severely burned. It's harder and more complex to find African American donors who match, and doctors expect it to take longer than usual because there aren't as many black organ donors as there are white donors.
Ian Alexander for Netflix
& Other Stories International Women's Day 2019 Campaign
Kyle Kuzma for ESPN
Build me a World
Bethany Mollenkof is a freelance photographer and filmmaker based in Los Angeles, CA.
© 2020 BETHANY MOLLENKOF


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Biografia
Nasce a Catania il 27 marzo 1953.

Si trasferisce con la famiglia a Roma nel 1964, dove consegue la Maturità classica al Liceo Mameli e la Laurea in Giurisprudenza presso l'Università degli Studi di Roma "La Sapienza".

Siciliano d'origine ma romano d'adozione, è sposato e ha due figlie.

Attivo fin dagli anni universitari nel panorama artistico e istituzionale di Roma, è proprio nella Capitale che nasce e si sviluppa il suo percorso manageriale alla guida di diverse società, alcune delle quali da lui fondate e tutte accomunate dalla medesima missione, ovvero la divulgazione e la fruizione al grande pubblico di grandi eventi culturali.

Per il suo impegno nella sua attività imprenditoriale, nel 2003 è stato insignito dall'allora Presidente Carlo Azeglio Ciampi dell'onorificenza di Commendatore al merito della Repubblica Italiana.

Su incarico del Ministro degli Affari Esteri e del Ministro per i Beni e le Attività Culturali ha diretto il Museo nazionale dell'Emigrazione Italiana (Complesso Monumentale del Vittoriano) dal 2009 al 2016.

Principali attività

Tra le mostre curate ed organizzate da Alessandro Nicosia dedicate all'arte europea dell'Ottocento e del Novecento, vanno ricordate esposizioni come Michelangelo e la Sistina, organizzata al Braccio di Carlo Magno in Vaticano e definita da papa Giovanni Paolo II una manifestazione «di così alto profilo artistico e culturale», e Il mondo di Snoopy del 1992, in occasione della quale Nicosia organizza un incontro tra il creatore dei Peanuts, Charles M. Schulz, e Federico Fellini. Il legame con il regista e con tutta la famiglia Fellini porta all'organizzazione di una serie di eventi organizzati in esclusiva in Italia e all'estero, anche nel Guggenheim Museum di New York.

Molteplici sono anche le mostre dedicate a noti personaggi italiani (come, per esempio, Luciano Pavarotti, Sophia Loren e Alberto Sordi), alle vittime della Shoah (2008-2013) e ai 150 anni dell'Unità d'Italia (2011).

Tra le attività organizzate da Alessandro Nicosia all'estero si ricordano quelle svolte al Pergamon Museum di Berlino (Pinakes), ad Hannover (Expo 2000), al Guggenheim Museum di New York (Fellini!), all'Ambasciata d'Italia a Washington (Regioni e Testimonianze e Garibaldi e l'America) e alla New York Public Library (Oriana Fallaci. Intervista con la storia).

Onorificenze

Note


Fair Ireland's farm sat slightly north of the village of Greenwich, bounded approximately by what would become 13th Street, Greenwich Avenue, West 11th Street and Greenwich Street. Although the Commissioners' Plan of 1811 laid out lot lines and streets; the property would remain mostly undeveloped into the 1820s.
At the time New York City's fire fighting force was composed of a disorganized collection of volunteer companies. When a fire broke out, young men in the neighborhood called "laddies" would scramble to the fire house. Nearby fire houses would vie with one another to arrive at the fire first, or to become more skilled at extinguishing it. The fire houses were often given catchy names like Oceanus and Empire. The company at No. 48 Horatio Street, Perry Hose Company No. 23, was named in honor of Commodore Matthew C. Perry who commanded a number of ships in several wars, most notably in the Mexican-American War and the War of 1812.
Although the company was "entitled" to 25 men, it had only 11 volunteers in 1855. Their blue-collar professions included plaster manufacturer, cartman, carpenter, feed store proprietor, stair builder and painter, among others.
In 1856 the City purchased the property and began construction on a new firehouse. Somewhat ironically, Commodore Matthew Perry died in 1858, the year after the new house was completed.
The extremely attractive Italianate building following the accepted fire house design—a central truck bay flanked by balanced openings. The hose engine and horses would be housed on the ground floor. The second and third floors would be a combination living quarters, hay loft and equipment rooms.
The firehouse was barely completed before it was nearly destroyed. As Independence Day approached in 1857 a fireworks display was planned in nearby Jackson Square. A Mr. Edge from Jersey City brought the crates of fireworks to the firehouse "for safekeeping" and they were placed in the back room on the first floor.
A few days later Sergeant Jacob I Sebring of Precinct No. 9 reported "Yesterday afternoon, about 6-1/2 o'clock, the Enginehouse of Perry Hose Company No. 23, located in Horatio-street, was discovered to be on fire." The fireworks had been set off, resulting in panic throughout the neighborhood.
Around the first week of February 1861 the fire fighters held a ball. Such annual social events were common within professional groups. Among the guests was John Kerrigan, brother of Congressman Kerrigan. The high-end affair was crashed by members of the Dead Rabbit gang—one of the notorious and dangerous gangs of the Five Points section. Kerrigan was later outspoken in the newspapers, delivering "what is said to have been deserved chastisement to Fatty Welsh and Johnny Aaron, known as leaders of the Dead rabbit organization, who visited a ball of Hose Company No. 23, and acted in an outrageous manner," as described by The New York Times.
Insulted, Fatty Walsh and Johnny Aaron plotted revenge. They got their chance about a week later when they encountered Kerrigan on February 12 on Mulberry Street. "Immediately an attack was made upon him with stones, which he managed to avoid by running," reported The Times. But he was "followed, however, by a yelling crowd of about twenty-five or thirty dead-rabbits." As Kerrigan neared City Hall Park he feared the rabble was about to overtake him, so he stopped, pulled a revolver, and shot twice. Although he did not hit any of the ruffians, the gunshots had the desired effect and the gang retreated.
The Civil War had an effect on the Perry Hose Company's roster. On August 19, 1863 Henry Ebbultzer was drafted into the Union Army; and two years later on March 15 Perry E. Wood's name was pulled in the draft lottery.
It was the last time the Perry Hose Company members would be together. The Act of 1865 did away with the mish-mash of volunteer companies and created the professional Metropolitan District fire department that covered Brooklyn and New York. Earlier that year, in May, the organization of the "Paid Fire Department" was announced. Alexander V. Davidson, foreman of Perry Hose Company No. 23, had been named Secretary of the new Department.
Davidson leased the former firehouse for just two years. By order of the Commissioners of the Sinking Fund a large amount of city-owned property was liquidated at auction on October 21, 1867. No. 48 Horatio Street "with brick building" sold for $7,400; significantly more than John Conolly had offered two years earlier.
As an interesting side note, Alexander V. Davidson went on to become Deputy Sheriff, then Sheriff in 1882. His career came to an ignominious end when he was indicted on three charges of grand larceny on March 21, 1884. Davidson skipped town, and when he was still on the lam in 1886 the contents of his impressive house at No. 8 Van Ness Place were auctioned. Among the items sold was "the inlaid marbletop table which used to belong to the Perry Hose Company No. 23, in the days of the old Volunteer Fire Department," according to the New-York Tribune on February 16.
The building became the property of Henry Tonjes, a real estate operator who lived two doors away at No. 44 Horatio Street. In the mid-1870s he leased it to H. H. W. Neslage who ran his livery stable here.
In the 1880s the building was shared by Fiss & Doerr, horse auctioneers; and A. De Cordova, "horses and cabs." By 1890 Fiss & Doerr had moved their horse auction stables to a much more commodious facility at Nos. 147 to 151 East 24th Street.
The building continued to house livery stables and horse-drawn trucks into the 20th century. At the turn of the century I. Moore & Co., "horses and trucks," was leasing the space from William Minnerly, who had owned it at least since 1889.
By the end of the First World War the upper floors had been fitted out as rented rooms. James Sanders was living here in 1920 when he and Josephine Nolan were arrested for breaking into an apartment building in Brooklyn.
The property was purchased by Adolph Leiser who renovated the first floor as a store and "dwelling" space on the upper floors. The ground floor became home to A. Leiser & Co., purveyors of "a complete line of scene painters' colors and supplies" for theatrical stage set designers.
One of Leiser's employees, Paul Wichert, lived in an upper floor apartment when Adolph Leiser died on September 29, 1937. Wichert received a generous $3,000 in his employer's will—nearly $50,000 today and an enormous windfall during the Great Depression.
In January 1955 the Horatio Street property changed hands for the first time in 35 years when it was sold by the Leiser estate. Nevertheless, A. Leiser & Co. remained in the ground floor at least until 1958.
In 1989 the old firehouse received a tender makeover when it was converted to a single-family home on the upper floors, and a garage and apartment on the ground level.
As always, meticulous research into these fascinating old buildings! I wanted to go back and look at a story you wrote about an older lady who helped neighborhood children learn more about history, putting on dramas and such. Can you direct me to the particular blog?
M. C. Perry's greatest accomplishments may his command of the Japanese expedition and as one of the founders of the U.S. Naval Academy. He also had his hand in the Brooklyn Navy Yard.


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HEADLINE Sisi reelected Egyptian president: state media
Sisi reelected Egyptian president: state media
By Qu Xiangyu | People's Daily app
Cairo (People's Daily) - State-owned Egyptian daily Akhbar Al Yawm reported on Thursday that incumbent Egyptian Preisident Abdul Fattah Sisi won the country's presidential election. More than 90% of the votes went to Sisi. However, the official results are scheduled to be released on April 2.
A total of 60 million people were eligible to vote in the three-day election from Monday to Wednesday.
File photo: Abdel-Fattah al-Sisi (Chinanews.com)


Jackson Heights native Elisa Lopez, 25, was just one of hundreds that gathered to try some of the street food on display at the third annual Viva la Comida Festival.
Lopez and her friends waited on the winding line for nearly 30-minutes to get a taste of the legendary dishes offered at the Arepa Lady food truck.
Although the 7-train was running on a limited schedule, hindering what could have been an even larger turnout for the festival, Lopez said she was nevertheless excited to see the turnout at 82nd Street and Roosevelt Avenue.
Jeff Orlick, curator of the festival, said there would have been more food trucks this year, but he had a hard time getting local vendors to leave their spot since many of them have such a die-hard following in the community.
Part of the success was in part thanks to $5,000 in funding from local Councilman Daniel Dromm.
82nd Street Partnership director Seth Taylor celebrated his final week with the business improvement district. He will be heading the NoHo Business Improvement in Manhattan.


When Costal Union's Bernard Mwalala picked up a hip injury in 2011 during a Tanzanian league game, he didn't know that what looked like a minor problem would end his playing career.
Then 28, Mwalala had just picked up the injury that would prematurely force the striker into the unchartered waters of management.
"I thought it was just a normal injury which would heal within a short period, but it turned out to be the one that would end my career," Mwalala told KweséESPN.
After numerous visits to hospital, he was advised to undergo surgery, which he declined, and ultimately decided to hang up his boots.
"I didn't see that coming," he continued. "I believed that it was a minor problem, when I was advised to undergo a hip replacement procedure I decided it was time to end my playing career."
Previously an explosive striker with excellent finishing instincts, Mwalala's 12-year playing career-which had included stints in Kenya, Uganda, Tanzania, Rwanda, Malaysia and Oman - was over.
When he called time on his career, the Kenya international hadn't countenanced a future as a coach, and was still household name in Tanzanian football after winning two league titles in 2006 and 2007 with giants Young Africans S.C.
He decided that he wasn't done with football, and his injury ultimately ignited a spark that made him feel he had more to offer the sport.
Simultaneously, third-division Magomeni FC were in the hunt for a new manager, and club officials saw enough in the 28-year-old to give him a chance even though he hadn't yet picked up his coaching badges.
"I moved to Magomeni FC in Tanga and at the same time took my coaching badges," he continued, "but after five months, I left because the club was facing financial challenges."
After leaving Magomeni, coaching offers were hard to come by and the once deadly frontman remained jobless for seven months.
During this time he was busy beefing up his football knowledge which he hoped would help him truly kickstart his career in the dugout.
Ultimately, an opportunity arrived with second-tier Muweza FC, although this too proved to be a false start.
"I was out of coaching until February 2013 when I joined Muweza FC, who were competing in the second division.
"We narrowly missed out on promotion to the top flight and I left at the end of the season."
After another spell as assistant to compatriot Yusuf Chipo at Coastal Union in 2014, his career truly took off back at Nzoia Sugar FC in Kenya.
"Only two people in the club's management believed in me." he continued. "The rest thought I was very inexperienced.
"However, with the blessings of the chairman, I took up the job with the sole aim of getting back the team to the Kenyan Premier League."
In his first season as Nzoia boss, the Millers finished fifth in the National Super League (NSL) and the following season they returned to the Kenyan Premier League after finishing top in the NSL with 92 points from 38 games, nine ahead of second-placed Kariobangi Sharks.
"It's the biggest achievement of my career so far," he added proudly. "Nzoia are special to me, they made me proud to lead the team to the top tier."
Mwalala ultimately came to broader public attention at the start of the new campaign, when his new boys stunned defending champions Tusker 5-2 to kickstart their top-flight campaign.
Nzoia eventually finished a respectable ninth, and the coach's achievements piqued the interest of underachieving Bandari.
With little experience, he installed an attractive attacking style of play at the team together with a resolute disciplined defensive setup.
His personality of a ruthless mentality, boldness and confidence, an attitude hewn from the failures and disappointments of years past, was seen in his team.
The result was an excellent second-place finish, Bandari's best return in the KPL.
Mwalala's troubled rout to the top of the league has allowed him to learn from his mistakes and refine his method, with the coach extolling the virtues of meticulous planning to underpin his attacking philosophy and produce a winning mentality.
Taking to coaching and management at a young age has allowed Mwalala to relate to younger players and get the best out of them. Bandari had one of the youngest squads in the KPL this season, and the coach is proud of his work with inexperienced talents.
"If you are good enough you are old enough." he says. "Age is never an issue when recruiting players."
An expansive style of play and a dogged defence made Bandari a hard team to beat.
Under the tutelage of Mwalala, they conceded a league-low of 20 goals, and lost just six matches.
They also defeated eventual champions Gor Mahia, with Mwalala demonstrating - again - his ability to get one over on one of the league's heavyweights.
"I am still learning," he concluded. "I am not yet where I want to be.
"My goal is to keep improving as a coach. Whatever happens in future happens, but for now I will keep sharpening my skills."
Following his stints in Magomeni, Muweza, Coastal Union, Nzoia Sugar and now Bandari, Mwalala's career has grown in stature.
The injury that forced him to hang up his boots is now a distant memory, and the youngster is fast becoming one of Africa's coaches to watch.


text:
package robot.ai.remotevideocontrol.main;

import android.graphics.Bitmap;
import android.util.Log;

import com.google.atap.tangoservice.TangoCameraIntrinsics;

import org.opencv.android.Utils;
import org.opencv.core.Mat;
import org.opencv.core.Size;
import org.opencv.highgui.Highgui;
import org.opencv.highgui.VideoCapture;
import org.opencv.imgproc.Imgproc;

import java.util.List;

import static java.lang.Thread.sleep;

/**
 * Created by scott on 7/20/15.
 */
public class ImageProcessor {
    private VideoCapture mCamera = null;
    private int mCameraId;
    private Size mPreviewSize;
    private Size mSmallSize;
    private boolean mDoProcess;
    private Mat mCurrentFrame;
    private Mat mCurrentSmall;
    private Bitmap mCurrentBitmap;

    public ImageProcessor() {
        this.mCameraId = TangoCameraIntrinsics.TANGO_CAMERA_COLOR;
        this.mSmallSize = new Size(455, 256);
        this.mDoProcess = true;
    }

    public void setupCamera() {

        if (mCamera != null) {
            VideoCapture camera = mCamera;
            mCamera = null; // Make it null before releasing...
            camera.release();
        }

        mCamera = new VideoCapture(mCameraId);

        List<Size> previewSizes = mCamera.getSupportedPreviewSizes();
        double smallestPreviewSize = 1280 * 720; // We should be smaller than this...
        double smallestWidth = 480; // Let's not get smaller than this...
        Log.v("CameraSetup", "Smallest Preview Sizes");
        for (Size previewSize : previewSizes) {
            Log.v("CameraSetup", "Width x Height " + previewSize.width + "x" + previewSize.height);
            if (previewSize.area() < smallestPreviewSize && previewSize.width >= smallestWidth) {
                mPreviewSize = previewSize;
            }
        }

        mCamera.set(Highgui.CV_CAP_PROP_FRAME_WIDTH, mPreviewSize.width);
        mCamera.set(Highgui.CV_CAP_PROP_FRAME_HEIGHT, mPreviewSize.height);
        mCurrentFrame = new Mat(mPreviewSize, Highgui.CV_CAP_ANDROID_COLOR_FRAME_RGB);
        mCurrentSmall = new Mat(mSmallSize, Highgui.CV_CAP_ANDROID_COLOR_FRAME_RGB);
        mCurrentBitmap = Bitmap.createBitmap(mCurrentSmall.width(), mCurrentSmall.height(), Bitmap.Config.RGB_565);
    }

    public void updateFrame() {
        Log.v("ImageProc", "updateing frame");
        long start = System.currentTimeMillis();
        boolean grabbed = mCamera.grab();
        if (grabbed) {
            long end = System.currentTimeMillis();
            Log.v("ImageProc", "Frame Grabbed in " + (end-start));
            start = System.currentTimeMillis();
            mCamera.retrieve(mCurrentFrame,
                    Highgui.CV_CAP_ANDROID_COLOR_FRAME_RGB);
            end = System.currentTimeMillis();
            Log.v("ImageProc", "Frame Retrieved in " + (end-start));
            start = System.currentTimeMillis();
            Imgproc.resize(mCurrentFrame, mCurrentSmall, mSmallSize);
            end = System.currentTimeMillis();
            Log.v("ImageProc", "Frame Resized from " + mCurrentFrame.width() + "x" + mCurrentFrame.height() + " to " + mCurrentSmall.width() + "x" + mCurrentSmall.height());
            Log.v("ImageProc", "Resizing time " + (end-start));
            start = System.currentTimeMillis();
            Utils.matToBitmap(mCurrentSmall, mCurrentBitmap);
            end = System.currentTimeMillis();
            Log.v("ImageProc", "Frame mapped to bitmap in " + (end-start));

            Log.v("ImageProc", "Frame Updated");
        } else {
            Log.v("ImageProc", "Frame Not Updated");
        }
    }

    public Bitmap getmCurrentBitmap() {
        Log.v("ImageProc", "Getting Bitmap " + mCurrentBitmap.getByteCount());
        return mCurrentBitmap;
    }

    public boolean ismDoProcess() {
        return mDoProcess;
    }

    public void setmDoProcess(boolean mDoProcess) {
        this.mDoProcess = mDoProcess;
    }
}

redpajama_set_name: RedPajamaGithub


text:
RPM Acquires UK Provider of Structural Movement Control Products
MEDINA, Ohio--(BUSINESS WIRE)--Oct. 30, 2017-- RPM International Inc. (NYSE: RPM) today announced that its USL Group has acquired Ekspan Holdings Limited, a provider of movement control products and services for bridges and major structures. Headquartered in Sheffield, United Kingdom, Ekspan has annual net sales in excess of $10 million. Terms of the transaction, which is expected to be accretive to earnings within one year, were not disclosed.
Established in 1990, Ekspan designs, manufactures and installs a range of specialty bridge bearings and expansion joints, as well as custom engineered solutions for bridges, high-rise buildings, wind turbines and other structures. Its products are used for new construction projects, as well as the refurbishment and replacement of existing installations. Among its high-profile projects is the iconic London Tower Bridge.
The acquiring entity, UK-based Universal Sealants (UK) Limited, is a specialist civil engineering and construction company focusing on bridges, tunnels, car parks, rail, airports and utility projects globally. It manufactures, supplies and installs construction products including bridge expansion joints, waterproofing membranes, protective coatings, structural drainage solutions, as well as a range of grouts, mortars, sealants and adhesives.
Ekspan is the third bolt-on acquisition for USL over the past 15 months. The others were U.S.-based businesses Prime Resins, a manufacturer of specialty chemicals and equipment for infrastructure construction and repair, and Applied Polymerics, Inc., a specialist civil engineering and construction organization focused on bridges, roads and major structures.
"Ekspan provides an opportunity to broaden USL's product offerings to include bearings for large structural movement control. By leveraging USL's wide geographic footprint, there are substantial opportunities to increase Ekspan's sales beyond its established customer base, especially in international markets," stated Frank C. Sullivan, RPM chairman and chief executive officer. "Ekspan's energetic management team will continue to run the business and drive its growth."


Princess Cut Ruby with Diamond Halo Set in Pure White Gol. Face Measure: 9.75 mm x 9.75mm Gemstone Weight: Total Natural Weight is 5.2ctw Diamond Weight: Total natural diamond weight is 1.3 carat. Excellent VS1-SI clarity / F-G color. Ring Size: FREE SIZING AVAILABLE.
Total Ring Weight: 6 Grams. Condition: New We design and manufacture these Jewels, these are not mass produced Jewelries! The item "Princess Cut Ruby with Diamond Halo set in Pure White Gold" is in sale since Tuesday, November 7, 2017.
This item is in the category "Jewelry & Watches\Fine Jewelry\Fine Rings\Gemstone". The seller is "sylvia_009" and is located in North Myrtle Beach, South Carolina. This item can be shipped to United States.


DOMINIQUE GALLERY does not take unsolicited artist submissions. If you have inquiries about the work in the gallery, please leave a message here or email info@dominiquegallery.com.
For artists: There will be an annual open call for submissions. Please follow the gallery page on Instagram and subscribe to the mailing list for updates on the open submission period.


You can also have a look at the whole 1929 or at August 21 across the years.
Have a look at the old newspapers from 21 August 1929 and get them!
Get a FREE Numerology report based on the digits of 21 August 1929!
Which were the important events of 21 August 1929 ?
Ahmed "Kathy" Kathrada: Leader of South African Communist Party.
X J Kennedy: American poet.
X Kennedy: American poet, translator, anthologist, editor, and author of children's literature and textbooks on English literature and poetry.
Herman Badillo: Puerto Rican-American lawyer and politician (d. 2014).
Marie Severin: American comic book artist and colorist.
...and if 21 August 1929 was your Birth Date then Join our Birthday Club!
Tell the world why 21 August 1929 is such a special date for you!


text:
Canaveral Port Authority breaks ground on new $163m Terminal 3 facility
At a space-themed ceremony, the Canaveral Port Authority and long-time cruise partner Carnival Cruise Line have broken ground for on the new Cruise Terminal 3 complex.
The new terminal, dubbed the Launch Pad, will be the home of Mardi Gras, the cruise line's newest and most innovative ship, beginning in 2020.
Port Authority commissioners and the Port's leadership team joined Carnival Cruise Line executives for the ceremonial ground-breaking at the project site as NASA's Spaceman planted a Carnival Cruise Line flag on a simulated lunar landscape.
The event theme, Go for Launch, was a nod to the Port's key role with the US space programme and the terminal's futuristic design, which was inspired by nearby Kennedy Space Centre.
The $163 million terminal project – the largest in the Port's 65-year history – is scheduled for completion in May 2020 and will be ready for the arrival of Mardi Gras to her year-round Port Canaveral homeport in October 2020.
"Today's ground-breaking is a historic milestone for our Port and underscores the long-standing partnership we have with Carnival," Port chief executive, John Murray, said.
"The trust and confidence we've earned with our great cruise partner has been the foundation of success and we are excited for what the future holds.
"We're building a great new terminal, for an innovative new ship, and looking forward to welcoming home Mardi Gras."
Port Canaveral and Carnival Cruise Line executives held a "pre-launch mission" news conference complete with a mock countdown, then grabbed shovels on the terminal construction site for the ceremonial first dig to officially kick off construction.
Carnival president, Christine Duffy, added: "We began our operations from Port Canaveral nearly 30 years go – coincidentally with our original ship of the same name.
"We've had a great relationship with Port Canaveral during that time and we're proud, honoured and excited that our newest and most innovative ship, Mardi Gras, will sail from the new Terminal 3.
"We are pleased to be the port's number one cruise line and Mardi Gras promises to be a spectacular addition to the Space Coast."
The contract to build the two-story, 187,000 sq. ft. terminal facility and adjacent six-story parking garage was awarded to Merritt Island, Florida-based Ivey's Construction.
The terminal will feature a high-tech baggage processing facility and a state-of-the-art check-in and security area on its second floor, with kiosks and seating for 1,700 guests.
Bolivia to host World Travel Awards Latin America Gala Ceremony 2019
Motel One sees sales grow in Europe
carnival corporation canaveral port authority
Carnival Corporation joins battle against single-use plastics
Carnival Vista to undergo floating repairs in Caribbean
Friends of the Earth questions environmental impact of cruise tourism
Profits fall as Carnival cuts guidance for financial 2019
Carnival celebrates Mardi Gras keel laying in Finland
Carnival Corporation reports strong 2018 but casts doubt on 2019 growth
Carnival Panorama celebrates construction milestone with coin ceremony in Italy
AIDAnova takes to seas for first time


text:
Emerging MDR-Mycobacterium avium subsp. avium in house-reared domestic birds as the first report in Egypt
Abdelazeem M. Algammal1,
Hany R. Hashem2,
Amenah S. Al-otaibi3,
Khyreyah J. Alfifi3,
Esraa M. El-dawody4,
Eman Mahrous4,
Helal F. Hetta5,
Ali W. El-Kholy1,
Hazem Ramadan6 &
Reham M. El-Tarabili1
Avian tuberculosis is a chronic and zoonotic disease that affects a wide variety of birds, mammals, and humans. This study aimed to estimate the frequency of Mycobacterium avium subsp. avium in some domestic birds based on molecular diagnosis, antibiogram profile, and PCR-based detection of inhA, rpoB, rpsL, and otrB antibiotic resistance-related genes.
A total of 120 fecal samples were collected from small flocks of house-reared domestic birds at Ismailia Governorate, Egypt. The collected samples were processed and subjected to the bacteriological examination. The antimicrobial susceptibility testing of the recovered isolates was performed using the broth microdilution method for the detection of minimum inhibitory concentrations (MICs). The genetic detection of the IS901confirmatory gene, inhA, rpoB, rpsL, and otrB genes was carried out using PCR.
The frequency of M. avium subsp. avium was 4.1% (5/120); 10% (4/40) in ducks, and 2.5% (1/10) in geese. The identification of the recovered isolates was confirmed using PCR, where all the tested isolates were positive for IS901confirmatory gene. The results of the broth microdilution method revealed that most of the recovered isolates exhibited multidrug resistance (MDR) to isoniazid, rifampicin, streptomycin, oxytetracycline, and doxycycline, and harbored the inhA, rpoB, rpsL, and otrB genes.
In brief, to the best of our knowledge this is the first report that emphasized the emergence of avian tuberculosis in house-reared domestic birds in Egypt. The emergence of MDR- M. avium subsp. avium is considered a public health threat. Emerging MDR-M. avium subsp. avium in domestic birds are commonly harbored the IS901, inhA, rpoB, rpsL, and otrB genes. Azithromycin and clofazimine revealed a promising in-vitro antibacterial activity against M. avium subsp. avium.
Avian tuberculosis is a chronic, debilitating disease that affects a wide variety of birds including wild and domestic birds [1]. The disease is caused mainly by Mycobacterium avium subsp. avium serotypes 1, 2, and 3, and genotype IS901 segment [2]. Mycobacteria are Gram-positive, aerobic, non-sporulated, non-motile, acid fast-bacilli. Mycobacteria are characterized by their lipid-rich cell wall which constitutes about 60–80% of their cell wall. Mycobacteria are opportunistic, intracellular pathogens that could withstand inside the macrophages and resist the host immune mechanism [3]. The bacilli of M. avium subsp. avium could resist most disinfectants, survive and multiply during adverse environmental conditions such as extreme temperature, low oxygen, and low pH [4].
M. avium subsp. avium transmitted between birds through the ingestion of contaminated food and water, inhalation of contaminated droplets, and from the adult birds to their young during the mouth feeding [5]. The infected birds with M. avium subsp. avium remain alive for a long time carrying the infection and subsequently shedding the pathogen in their dropping that results in the transmission of infection to other birds as well as humans [6, 7]. The infected birds may exhibit certain clinical signs such as diarrhea, emaciation, atrophy of breast muscle, and the development of tuberculous nodules in the last stage of the disease, especially in internal organs such as the intestine, liver, spleen, and lung [6].
Avian tuberculosis has public health importance, especially with immunocompromised persons that handle the infected birds or eat their insufficiently cooked meat [8, 9]. Most of the infected cases with M. avium subsp. avium are keeping domestic or pet birds in their home [10]. M. avium subsp. avium not only infects birds, but also could infect pet animals, pigs, and immunocompromised humans. Avian tuberculosis leads to high economic losses including; 1-High condemnation rates in poultry slaughterhouses, 2-Drop in egg production, 3-Weight loss and emaciation of infected birds, 4-Sudden death, and high mortality rates, and 5-Loss of endangered species of birds [11,12,13]. Avian tuberculosis is considered a serious problem in wild birds, especially the endangered species, so the valuable species should be checked regularly [14].
M. avium subsp. avium has a complex thick cell wall that is responsible for the intrinsic multidrug resistance and virulence [15, 16]. The diagnosis of M. avium complex, especially M. avium subsp. avium is difficult; as there are no specific clinical signs, it depends on;1-The culture technique that is recommended by OIE as the gold-standard technique, 2-The microscopical examination of acid-fast bacilli using Ziehl-Neelsen staining, and 3- PCR-based confirmatory diagnosis [10, 17, 18].
The multidrug resistance phenomena have increased globally. The emergence of multidrug-resistant bacterial pathogens from various origins was reported by several recent studies that reflect public health threats [19,20,21,22,23,24,25,26]. Treatment of avian tuberculosis is extremely difficult due to the development of antimicrobial resistance of M. avium complex to most antibiotics. The antimicrobial resistance is attributed to either intrinsic factors such as the waxy lipoid cell wall or mutation in some genes [27]. The most effective drug used in the treatment of avian tuberculosis is azithromycin [28]. Most types of M. avium complex have a weak response to the treatment due to the development of antibiotic resistance [27]. This is the first report concerning the emergence of MDR-M. avium subsp. avium in house-reared domestic birds in Egypt. This study aimed to estimate the frequency of Mycobacterium avium subsp. avium in some domestic birds based on molecular diagnosis, antibiogram profile, and PCR-based detection of inhA, rpoB, rpsL, and otrB antibiotic resistance-related genes.
A total of 120 fecal samples from different domestic birds' species (chicken (n = 40); 20 apparently healthy and 20 diseased birds, ducks (n = 40); 20 apparently healthy and 20 diseased birds, and geese (n = 40); 20 apparently healthy and 20 diseased birds) were collected from Private house-reared flocks from August 2018 to March 2019 from Ismailia Governorate, Egypt. The diseased birds were suffered from persistent diarrhea and emaciation together with a history of treatment failure with oxytetracycline. The collected samples were prepared according to Parashar et al. [29] and Payeur [30].
Decontamination of fecal samples
The collected specimens were diced by sterile disposable surgical blades and then homogenized in a sterile porcelain mortar and pestle. The homogenized samples were suspended in 10 ml of PBS (Thermo Fisher Scientific, USA). The decontamination was performed as described by Sattar et al. [31]. Briefly, samples were inoculated in 0.9% Hexadecylpryridinium Chloride Monohydrate (HPC) (Sigma-Aldrich, USA), and then were incubated at 37 °C for 24 h. The mixture was centrifuged at 10 °C (3000 xg) for 15 min. The obtained pellets were re-suspended in 1 ml of sterile D.W., then were mixed (using vortex/ 500 rpm for 30 s.) with an equal volume of antibiotic suspension (vancomycin: 100 μg/ml, nalidixic acid: 100 μg/ml, and amphotericin: 50 μg/ml) (Oxoid, UK), followed by incubation at 37 °C for 24 h.
Isolation and identification of M. avium subsp. avium from fecal samples
The processed fecal samples were streaked on Middlebrook 7H10 agar (Oxoid, UK); media was supplemented by a- 5 ml/l Glycerol (Oxoid, UK) and b-Middlebrook OADC Growth Supplement (Oxoid, UK). The inoculated plates were incubated at 37° ± 2 °C under microaerophilic conditions where a CO2 sachet (Oxoid, UK) is placed in a tightly closed anaerobic jar. The incubated plates were examined for bacterial growth at 2, 4, 6, 8, and 10 weeks post-incubation. The suspected colonies were identified according to their culture characters, morphological characters using Ziehl-Neelsen staining, and biochemically using niacin production, nitrate reduction, tween-80 hydrolysis, thermo-stable catalase at 68 °C, and arylsulfatase tests as described by Kubica [32]. Besides, the identification of the recovered isolates was confirmed by PCR-based detection of the IS901 gene (the most conserved gene in M. avium subsp. avium) as described in Table 1.
Table 1 List of oligonucleotide sequences and cycling conditions that used in this study
Antimicrobial susceptibility testing using broth microdilution method
The detection of minimal inhibitory concentrations (MICs) of the tested antimicrobial agents was carried out using the broth microdilution method according to the procedures of CLSI [33]. The test was performed using Middlebrook 7H10 broth (Oxoid, UK). The MIC for each antibiotic for each tested isolate was the mean of two repeated tests. Mycobacterium avium ATCC 700898 was used as a control strain. The MIC breakpoints of the tested antimicrobial agents were expressed as sensitive, intermediate, and resistant as described by the CLSI guidelines. The tested isolates were classified into Multidrug-resistant (MDR: the resistance to at least isoniazid and rifampicin), Extensively drug-resistant (XDR: resistant to isoniazid and rifampicin as well as to fluoroquinolones, and at least one of the second-line drugs such as kanamycin, amikacin, and capreomycin), and Pan-drug resistant (PDR: resistant to all antimicrobial agents listed) according to Prasanna and Niranjan [34].
Molecular detection of IS901, inhA, rpoB, rpsL, and otrB genes
PCR was used to detect the IS901 gene to confirm the diagnosis of the recovered isolates as well as to investigate the presence of inhA, rpoB, rpsL, and otrB genes in the recovered isolates. Extraction of DNA was performed using the QIAamp DNA Mini Kit (Qiagen, GmbH, Germany/ Catalogue No.51305). The PCR reaction performed in a "25- μl" reaction volume containing; "12.5 μl" of Emerald Amp Max PCR Master Mix (Takara, Japan), one μl of each primer of 20 pmol concentration, 4.5 μl of water, and 6 μl of DNA template. The oligonucleotide primers sequences (Metabion International AG, Germany) and their recycling conditions are illustrated in Table 1 [35,36,37,38,39]. Positive control strains (kindly provided by A.H.R.I, Egypt) and negative controls (DNA-free) were involved in each PCR run. Finally, the agar gel electrophoresis was carried out using 1.5% agarose stained with ethidium bromide 0.5 μg/ml (Fermentas, Germany). The gel was visualized by a gel documentation system (Thermo Fisher Scientific, Waltham, MA, USA).
The statistical analysis of the obtained findings was carried out using Chi-square (SAS software, version 9.4, SAS Institute, Cary, NC, USA) (significance level; P < 0.05). The correlation analyses were performed between different tested antimicrobial agents as well as the antibiogram results and the presence of resistance genes using R software (version 4.0.2; https//www.r-project.org/).
Phenotypic characteristics of the recovered M. avium subsp. avium from house-reared domestic birds
In the present study, the colonies of the recovered M. avium subsp. avium isolates were small, round, creamy color, and sticky on a Middlebrook 7H10 agar. The colonial growth was obtained within 2 weeks after incubation. The microscopical examination of the retrieved isolates (using Ziehl-Neelsen staining) revealed non-sporulated and non-motile acid-fast bacilli. The recovered isolates were positive for the arylsulfatase test, while were negative to the niacin production, nitrate reduction, thermo-stable catalase, oxidase, and tween − 80 hydrolysis tests (Table 2).
Table 2 Phenotypic characteristics of M. avium subsp. avium
The frequency of M. avium subsp. avium in different species of examined domestic birds
The bacteriological examination revealed that the frequency of M. avium subsp. avium was 10% (4/40) in the examined ducks and 2.5% (1/40) in the examined geese. Moreover, the examined chicken samples were negative to M. avium subsp. avium. The total frequency of M. avium subsp. avium was 4.1% (5/120). All the retrieved isolates were originated from diseased birds suffering from persistent diarrhea and emaciation (Table 3 and Fig. 1). Statistically, there is a significant difference (P < 0.5; P = 0.008783) in the frequency of M. avium subsp. avium among examined samples of different bird species.
Table 3 The frequency of M. avium subsp. avium among different examined birds
The frequency of M. avium subsp. avium among the examined domestic birds (Ducks, geese, and chicken)
Antibiogram of the recovered M. avium subsp. avium isolated from domestic birds
In the present study, the results of the broth microdilution method exhibited harmony with the results of the disc diffusion method. Four isolates were resistant to doxycycline, streptomycin, oxytetracycline rifampicin, and isoniazid with detectable MICs of > 8 μg/ml, > 8 μg/ml, > 8 μg/ml, > 2 μg/ml, and > 0.25 μg/ml, respectively. All the tested isolates (n = 5) were sensitive to azithromycin (MIC ≤2 μg/ml) and clofazimine, while only one isolate was sensitive to rifampicin. Moreover, all the tested isolates were resistant to isoniazid (MIC > 0.25 μg/ml) (Table 4 and Fig. 2). The correlation analyses were conducted among different tested antimicrobial agents. The obtained results showed strong positive correlations between (0.5–1): CFZ and AZM (r = 1); RF, STR, and OT(r = 1); DOX, STR, and OT(r = 1); OT, DOX, RF, and INH (r = 0.97); STR and OT (r = 0.97) and OT, DOX, and STR (r = 0.88) as described in Fig. 3.
Table 4 The results of the broth microdilution method for detection of MICs of the tested antimicrobial agents
The heat map illustrates the susceptibility of the recovered M. avium subsp. avium isolates to different tested antibiotics
The heat map illustrates the correlation between the different tested antimicrobial agents against the recovered M. avium subsp. avium isolates. Red and blue colors refer to the negative and positive correlations, respectively
PCR-based detection of IS901confirmatory gene and inhA, rpoB, rpsL, and otrB antibiotic resistance-related genes in the recovered M. avium subsp. avium isolates
In the present study, the identification of the recovered isolates is confirmed using PCR, where all the tested isolates were positive for the IS901 confirmatory gene with a specific amplicon size of 577 bp. Moreover, PCR was used to detect the inhA, rpoB, rpsL, and otrB antibiotic resistance-related genes. Our finding revealed that all the tested isolates (100%, 5/5) (four duck isolates and one goose isolate) are harbored inhA genes with a specific amplicon size of 810 bp. Moreover, the rpoB, rpsL, and otrB resistance genes are detected in four recovered isolates (80%, 4/5) (Three of duck origin and one isolate of geese origin) with specific amplicon size of 347 bp, 592 bp, and 947 bp, respectively. The distribution of IS901, inhA, rpoB, rpsL, and otrB genes among the recovered M. avium subsp. avium isolates was illustrated in Table 5 and Fig. 4. Statistically, there is no significant difference in the distribution of IS901, inhA, rpoB, rpsL, and otrB genes in the recovered isolates (P > 0.05, P = 0.9915) as illustrated in Table 5.
Table 5 The distribution of IS901 gene and antibiotic resistance-related genes associated with the retrieved isolates
The distribution of IS901, inhA, rpoB, rpsL, and otrB genes among the recovered M. avium subsp. avium isolates
The correlation between the phenotypic and genotypic resistance patterns of the isolated M. avium subsp. avium
Regarding the correlation between the in-vitro antibiotic resistance and the genotypic resistance patterns, our finding proved that 80% (4/5) of the retrieved M. avium subsp. avium isolates (three isolates of duck origin and one isolate of geese origin) exhibited multidrug resistance patterns to isoniazid, rifampicin, streptomycin, oxytetracycline, and doxycycline, and harbored the inhA rpoB, rpsL, and otrB genes as described in Table 6. The correlation analyses were conducted between various tested antimicrobial agents and the detected antibiotic resistance-related genes in the recovered M. avium subsp. avium isolates. Our results proved strong positive correlations (r = 0.5–1) between: ropB gene and RF (r = 1); inhA gene and INH (r = 0.97); otrB and OT(r = 0.88); rpsL gene and STR (r = 0.88); otrB gene and DOX (r = 0.88) as illustrated in Fig. 5.
Table 6 Phenotypic and genotypic resistance patterns of the isolated M. avium subsp. avium
The heat map illustrates the correlation between the different tested antimicrobial agents and the antibiotic resistance-related genes in the recovered M. avium subsp. avium isolates. Red and blue colors refer to the negative and positive correlations, respectively
Regarding the phenotypic characteristics of M. avium subsp. avium, our findings proved no diversity in both morphological and biochemical characteristics among the recovered isolates and revealed a remarkable harmony between different retrieved isolates from duck and geese origins. Our results agreed with those reported by Zhu et al. [35] and Bhalla et al. [40]. The decontamination of fecal samples using 0.9% Hexadecylpryridinium Chloride Monohydrate and the antibiotic mixture is the best method to increase the recovery of M. avium subsp. avium from the fecal samples of examined birds [31]. The culture technique is considered the gold standard method used for the identification of M. avium subsp. avium as it is the most sensitive and specific method (never give false-positive results), but it requires more time [17]. On the other hand, the direct microscopical examination of acid-fast bacilli is not accurate and requires a high load of microorganisms (Approximately, 10.000 bacteria/g) to be effective. Moreover, it may give false-negative results due to its low sensitivity and specificity [41, 42].
In the present study, the frequency of M. avium subsp. avium in the examined house-reared birds agreed with that previously reported by Kindu and Dagnaw [13] who isolated M. avium subsp. avium from domestic birds in Ethiopia with a prevalence of 4.26% (12/282). Moreover, in Bangladesh, Reza et al. [43] reported that the prevalence of M. avium subsp. avium in droppings of different examined birds was 3.75% (3/80). On the other hand, in the Czech Republic, Shitaye et al. [44], and Kazda et al. [45] reported that turkeys are susceptible to M. avium subsp. avium, while ducks, geese, and water birds are resistant to avian tuberculosis. Furthermore, higher prevalence (11.1%) of M. avium subsp. avium was reported in the Czech Republic by Dvorska [46]. The prevalence of infection in birds mainly increased due to the bad hygienic conditions, overcrowding, and multi-aged birds' populations. Moreover, some birds are highly susceptible to avian tuberculosis due to genetic factors [47, 48]. The prevalence of infection in birds mainly increased due to the bad hygienic conditions, overcrowding, and multi-aged birds' populations. Moreover, some birds are highly susceptible to avian tuberculosis due to genetic factors [49]. The infection of birds occurs due to the ingestion of contaminated food and water with feces of infected birds, and also may occur via the respiratory route [6]. Besides, avian tuberculosis could be transmitted to the immunocompromised persons through the handling of carrier birds or via the ingestion of insufficiently cooked meat of infected birds [8].
In the current study, PCR was used to confirm the diagnosis of the recovered isolates depending on the detection of the IS901 gene that is specific to M. avium subsp. avium. Our results emphasized the presence of the IS901 gene in all tested isolates. Our findings agreed with those reported by Pavlik et al. [49] who detected the IS901 gene in all tested M. avium subsp. avium strains originated from birds. M. avium subsp. avium are characterized by the existence of the specific insertion sequence IS901 in their genome. PCR could be used as a molecular tool to detect the pathogenic variant of M. avium subsp. avium as well as the screening of elderly birds [50].
Concerning the antibiogram of the retrieved M. avium subsp. avium isolates, our findings emphasized the promising in-vitro antimicrobial activity of azithromycin and clofazimine. M. avium complex commonly exhibits a potential sensitivity to macrolides, especially azithromycin [51]. Moreover, Huang et al. [52] revealed that clofazimine gives optimistic results in the treatment of M. avium-associated infections. Higher frequencies of antimicrobial resistances were identified to doxycycline, streptomycin, oxytetracycline, rifampicin, and isoniazid using the broth microdilution method. In a previous study by Pang et al. [50], among the recovered Mycobacterium avium complex strains, Mycobacterium avium was the most resistant to the tested antimicrobials with a resistance rate of 73.68%. In the present study, most of the retrieved M. avium subsp. avium isolates were resistant to isoniazid, rifampicin, streptomycin, oxytetracycline, and doxycycline, and harbored the inhA, rpoB, rpsL, and otrB genes. The multidrug resistance in Mycobacterium species is defined as the resistance to at least both isoniazid and rifampicin [53]. The complicated cell wall structure, the presence of mycolic acid, and the lipoidal contents are the main factors that control the intrinsic multidrug-resistance of the M. avium complex [15]. The resistance to rifampicin is common in the M. avium complex and mainly occurred due to the mutation of the rpoB gene that encoding for the β-subunit of the DNA-dependent RNA polymerase M. avium complex [54]. Moreover, the resistance to the oxytetracycline is attributed to the presence of the otrB gene encoding for the integral membrane protein that is responsible for the efflux of oxytetracycline from the cell [55]. Aminoglycosides exert their action by ribosomal binding near site A with subsequent inhibition of protein synthesis [56]. The Resistance to streptomycin is common in the M. avium complex and occurred due to mutations in the rpsL gene encoding the ribosomal protein (S12) [57]. The inhA gene encodes for the enoyl acyl reductase which is involved in the mycolic acid synthesis that is responsible for the isoniazid resistance [58]. Briefly, the existence of multidrug resistance in the M. avium complex is attributed to several factors including 1-The intrinsic resistance due to the complex thick cell wall and the presence of mycolic acid, 2-The presence of specific antimicrobial resistance genes, and 3-Mutations that takes place in certain genes such as rpsL and rpoB genes that adversely affect the activity of the antimicrobial agents [59].
Gene sequencing of the antibiotic-resistance related genes of isolates (rpoB and rpsL) should be carried out for the detection of mutations that adversely affect the activity of the antimicrobial agents.
In conclusion, to the best of our knowledge, this is the first report that emphasized the emergence of MDR-M.avium subsp. avium in house-reared domestic birds (duck and geese) in Egypt. The emergence of MDR-M. avium subsp. avium is considered a public health threat. The combination of phenotypic and genotypic characterization is an effective epidemiological tool for the identification of M. avium subsp. avium. Emerging MDR-M. avium subsp. avium in house-reared domestic birds are commonly harbored the IS901, inhA, rpoB, rpsL, and otrB genes. Azithromycin and clofazimine revealed a promising in-vitro antimicrobial activity against M. avium subsp. avium. The continuous monitoring of bird flocks is essential to reduce the prevalence of avian tuberculosis. The regular application of antimicrobial susceptibility testing is necessary to determine the most effective antimicrobial agent and detect the emerging MDR-strains.
All the data has been included in the manuscript.
OIE:
World Organization for Animal Health
Clinical and Laboratory Standards Institute
PDR:
Pan-drug resistant.
XDR:
Extensive drug-resistant
Multi-drug resistant
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Department of Bacteriology, Immunology and Mycology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt
Abdelazeem M. Algammal, Ali W. El-Kholy & Reham M. El-Tarabili
Department of Microbiology and Immunology, Faculty of Pharmacy, Fayoum University, Fayoum, 63514, Egypt
Hany R. Hashem
Biology Department, College of Sciences, Tabuk University, Tabuk, 71491, Saudi Arabia
Amenah S. Al-otaibi & Khyreyah J. Alfifi
Animal Health Research Institute, Dokki, Giza, 12618, Egypt
Esraa M. El-dawody & Eman Mahrous
Department of Medical Microbiology and Immunology, Faculty of Medicine, Assuit University, Assuit, 71515, Egypt
Helal F. Hetta
Hygiene and Zoonoses Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35516, Egypt
Hazem Ramadan
Abdelazeem M. Algammal
Amenah S. Al-otaibi
Khyreyah J. Alfifi
Esraa M. El-dawody
Eman Mahrous
Ali W. El-Kholy
Reham M. El-Tarabili
A.M.A. conception and study design. A.M.A, E.M.E, A.W.E, H.R.H, H.F.H, K.J.A, E. M, A.S.A, H. R, and R.M.E; conducted the experiments. A.M.A. and E.M.E. drafted the manuscript. A.M.A, K.J.A, E.M.E, E. M, A.S.A, H.R.H, H.F.H, A.W.E, H. R, and R.M.E; acquisition of data, statistical analysis, and interpretation of data. AMA; critically reviewing the article. All authors have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.
Correspondence to Abdelazeem M. Algammal.
The handling of birds and all used protocols were approved by the Animal Ethics Review Committee of Suez Canal University (AERC-SCU), Egypt. The written informed consent is not applicable. We confirmed that all methods were performed in accordance with the relevant guidelines and regulations.
Algammal, A.M., Hashem, H.R., Al-otaibi, A.S. et al. Emerging MDR-Mycobacterium avium subsp. avium in house-reared domestic birds as the first report in Egypt. BMC Microbiol 21, 237 (2021). https://doi.org/10.1186/s12866-021-02287-y
M. avium subsp. avium
House-reared domestic birds, prevalence
MDR, antibiotic resistance-related genes


text:
Notice of Annual General Meeting of Shareholders to be Held on December 28, 2018 November 26, 2018
SEOUL, South Korea, Nov. 26, 2018 /PRNewswire/ -- Hanwha Q CELLS Co.,&nbspLtd. ("Hanwha Qcells" or the "Company") (NASDAQ: HQCL), a global leading photovoltaic manufacturer of high-performance, high-quality solar modules, today announced that the annual general meeting of shareholders (the "AGM") of the Company will be held at 9:00 AM Korea Standard Time on December 28, 2018 at the Company's building at Room 301 on the 3rd Floor of 86 Cheonggyecheon-ro, Jung-gu, Seoul, Korea 04541, to consider and, if thought fit, to pass and approve the following resolutions:
as an ordinary resolution, that Hee Cheul (Charles) Kim, who was elected by the directors of the Company as a director on October 1, 2018, be elected as a director and Chairman of the Company to hold office in accordance with the Articles of Association of the Company for a two-year term with effect from the date of the AGM
as an ordinary resolution, that Jung Pyo (Jay) Seo, who was nominated for the third term by the directors of the Company as a director on November 20, 2018, be re-elected as a director of the Company to hold office in accordance with the Articles of Association of the Company for a two-year term with effect from the date of the AGM
as an ordinary resolution, that Young Soon Kim, who was nominated for the second term by the directors of the Company as a director on November 20, 2018, be re-elected as a director of the Company to hold office in accordance with the Articles of Association of the Company for a two-year term with effect from the date of the AGM
as an ordinary resolution, that Ernst & Young Han Young be appointed as independent auditor of the Company for the financial statements ending December 31, 2018
Holders of record of ordinary shares at the close of business on November 16, 2018 (Eastern Time) will be entitled to attend and vote at the AGM. A holder entitled to attend and vote is also entitled to appoint a proxy to attend and, on a poll, vote instead of him and that proxy need not be a holder of ordinary shares of the Company. Whether or not you expect to attend the AGM in person, please mark, date, sign and return the enclosed proxy card to: Board Secretary, Hanwha Q CELLS Co.,&nbspLtd., 5th Floor, 86 Cheonggyecheon-ro, Jung-gu, Seoul, Korea 04541. The proxy card shall be received by the Company's Board Secretary no later than 5:00 PMKorea Standard Time on December 26, 2018 to ensure your representation and the presence of a quorum at the AGM. Sending in your proxy will not prevent you from voting in person at the AGM.
Holders of American Depositary Shares representing ordinary shares will be entitled to vote through the depositary at the AGM. Please refer to the voting materials delivered to you by the depositary for how you may instruct the depositary to vote.
Hanwha Q CELLS Co.,&nbspLtd. (NASDAQ: HQCL) is one of the world's largest and most recognized photovoltaic manufacturers for its high-performance, high-quality solar cells and modules. It is headquartered in Seoul, South Korea (Global Executive HQ) and Thalheim, Germany (Technology & Innovation HQ) with its diverse international manufacturing facilities in Malaysia and China. Hanwha Qcells offers the full spectrum of photovoltaic products, applications and solutions, from modules to kits to systems to large-scale solar power plants. Through its growing global business network spanning Europe, North America, Asia, South America, Africa and the Middle East, the company provides excellent services and long-term partnerships to its customers in the utility, commercial, governmental and residential markets. Hanwha Qcells is a flagship company of Hanwha Group, a FORTUNE Global 500 firm and a Top 10 business enterprise in South Korea.
This press release contains forward-looking statements. These statements constitute "forward-looking" statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates" and similar statements. Among other things, the quotations from management in this press release and the Hanwha Qcells' operations and business outlook, contain forward-looking statements. Such statements involve certain risks and uncertainties that could cause actual results to differ materially from those expressed in or suggested by the forward-looking statements. Further information regarding these and other risks is included in Hanwha Qcells filings with the U.S. Securities and Exchange Commission, including its annual report on Form 20-F. Except as required by law, Hanwha Qcells does not undertake any obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.


Dunno why but I keep looking for the General Chatter forums above Food & Recipes. I'm I the only one that thinks Food & Recipes should be at the bottom of the forum?
Thats weird as I look for it there too! Think Im used to the BnB layout, so know GC is not right at the very bottom. I think Recipes would make more sense at the bottom, as they are more informative and not really a discussion area?
That's what I think Info, resources and non discussion areas need to go at the bottom.
I agree! I'm used to the BnB forum layout still!
Find more posts on forum, layout.


text:
package com.github.ledoyen.automocker.api.jms;

import java.util.Optional;

import org.springframework.util.ErrorHandler;

import com.github.ledoyen.automocker.api.Resettable;

public class ErrorHandlerMock implements ErrorHandler, Resettable {

    private final Optional<ErrorHandler> delegate;
    private Throwable lastCatched = null;

    ErrorHandlerMock(Optional<ErrorHandler> delegate) {
        this.delegate = delegate;
    }

    @Override
    public void handleError(Throwable t) {
        lastCatched = t;
        delegate.ifPresent(e -> e.handleError(t));
    }

    public Optional<Throwable> getLastCatched() {
        return Optional.ofNullable(lastCatched);
    }

    @Override
    public void reset() {
        this.lastCatched = null;
    }
}