text:
On Sunday the 18th. of June, 1815, near the small Belgian village of Waterloo BELOW LEFT on the rolling agricultural plains a serious power vacuum was created in Europe. On that day the French Emperor Napoleon Bonaparte was defeated by the British under the command of Sir Arthur Wellesley, better known as the Duke of Wellington. But it was a close run thing. The British had withstood repeated frontal attacks by the French all day then in the evening the Prussian army appeared unexpectedly on the battlefield, driving hard into the French flank. Wellesley saw his chance and pushed his infantry forward, Napoleon's army buckled, and then fled from the field in total dissarray. The timely intervention by the Prussian army under the command of the insane but tactically brilliant Field Marschall Gebhard Leberecht von Blücher, Fürst von Wahlstatt, effectively turned the battle into a rout. The charismatic von Blücher had once informed Wellington that he was pregnant with an elephant that had been sired by a French soldier!!!
But insane or otherwise, at the time of the Battle of Waterloo von Blücher was not representing the nation of Germany; Germany was not actually a nation in the traditional sense at all, rather it was a collection of states with a reasonable degree of commonality of language throughout - although differences in the pronunciation, spelling, and even the actual words for some things differed from state to state, a situation which was not "officially" rectified until as late 1914 and which is still apparent to some degree to this day.
Prussia bordered Russia to the north; the other states collectively covered a vast area of land from the Baltic coast line right down to the state of Baden which sits next to France's Department of Alsace in the south east. Alsace was originally part of the Holy Roman Empire but it was progressively annexed by the French in the 17th. century. A long time bone of contention for the two neighbours, it had changed hands no less than FOUR times in 75 years. Bordering Austria, Bavaria was a kingdom in it's own right at that time and was the last state to enter the German confederation - indeed Bavaria still had it's own Crown Prince - Ruprecht - at the time of the Great War. Prussian politicians, led by the Iron Chancellor Otto von Bismark, endeavoured to unite the Germanic states, but it was not until a short time after the Franco-Prussian war of 1870 that Germany finally became one nation.
And with a national identity came the desire for empire.
The might and efficiency of the German army under the leadership of the Prussian General Von Moltke was so great that both the Austrian and French armies were comprehensively defeated in short order in the so called German Wars of Unification of 1866 and 1870 respectively. This is actually something of an over-simplification of the situation as the reality of the war with Austria in 1866 was closer to that of a civil war within Germany itself, so divided were the Germanic states as to which side - Prussia or Austria - they wished to offer their allegiance to. Suffice it to say the Prussian army and her allies prevailed.
In the case of the later Franco Prussian war of 1870, victorious German troops, this time from practically all of the Germanic states, so devastated their French opponents that they were able to march into Paris in a matter of only a few weeks whereupon they promptly imposed punitive terms which included the annexation to Germany of vast areas of France, principally the Department of Alsace once again, but also the Department of Lorraine. Naturally such a crushing defeat did not go down too well with the French nation so steps were taken to ensure that Germany could not repeat the same thing a second time. Due to the annexation of the Department of Lorraine the border with Germany in the region of the Plain of Woevre had moved much closer - it was now only of the order of 40 miles or so away. The most direct road to Paris from Germany through the plain was therefore also correspondingly shorter so something would have to be done to shore up this gaping breach in the French capital's defences. The military engineer, General Raymond Adolphe Sere De Rivieres - seen right, was appointed to plan and oversee the fortification of the town of Verdun which lay at a point on the route which strategically offered the best possible opportunity for defence. Accordingly a ring of forts was quickly built on hill ridges close to the city, then work immediately began on a secondary ring some distance further out, again on the strategically important high ground. Finally the gaps between the forts were further strengthened by the addition of "ouvrages" - smaller forts - fortified troop shelters, artillery emplacements, and a network of small gauge railways to run ammunition and personnel quickly between all the key areas. The city itself had been massively fortified during the reign of Louis XIV in the mid 1600s when a vast citadel was constructed by another formidable French military engineer, the Marquis de Vauban.
An extensive program of modification and improvements to both the armaments and reinforcement of all the fortifications was carried out right up to the outbreak of war in order to keep pace with the increasingly formidable and ever more efficient German artillery, Churned out by the likes of Skoda and the mighty Krupps factory in Essen, the largest and most devastating of the siege artillery was the 420 mm "Big Bertha" Krupps howitzer - seen left.
Thus by the time France entered the Great War in 1914 Verdun had become a formidable ring of steel and concrete which Germany would find exceedingly hard to get past. Sadly though that was not how things quite turned out. During the Battle of Verdun which began in February 1916, the ring of steel almost caused France's downfall through a combination of appalling tactical decisions, bad soldiering, poor leadership, and sheer, bloody minded obstinance.
Out front, standing on the highest point for miles around was the gigantic fort of Douamont. Visible for miles from the plain below, like the bow of a giant ice breaker upon which it was thought the waves of attacking German soldiers would break and scatter, it was designed to be the king pin in the ring of steel. Armed to the teeth and massively fortified, the fort should have been impregnable, however during the first few weeks of the war in 1914 the French military authorities, seeing what had happened to the Belgian forts around Liege when the German heavy siege artillery arrived, promptly had a serious change of mind. They dramatically down sized all the Verdun fortress garrisons, replacing the young, able bodied soldiers with elderly reservists in order to provide more line infantry.
But perhaps most significantly they removed all none permanent artillery from the forts for re-deployment with the mobile army elsewhere, leaving only the armoured turrets - and not all of the forts had these installations to begin with!
On 24th. February 1916, within only a few days of the start of the Battle of Verdun, and quite contrary to what the New York Times article suggests - right - Douamont fell with hardly a shot being fired. And even more bizarrely it fell to a most unlikely individual, a German Pioneer Sergeant from Thuringia by the name of Kunze, who was attached to the 24th. Brandenburg Regiment. Depending upon which version of the story you read the disaster came about in a variety of ways - Kunze - left -was blown into Douamont's moat by a near miss, he climbed down the counterscarpe wall into the ditch on some old wooden poles, etc. etc. etc. What is without doubt though is the fact that he took the fort almost single handed, assisted in no small part by a comedy of errors on the part of the defenders! Accompanied by only a handful of men Kunze entered Douamont via an open doorway on the fort's Rue du Rempart and swiftly locked up the garrison who were eating dinner in a barrack room deep within the fort's lowest level totally oblivious to the battle raging outside!
A matter of only a few weeks later Fort Vaux also fell despite a spirited defence by the garrison; indeed it did not fall for want of bravery nor lack of ammunition, it fell for the simple need for drinking water. By July 12th. 1916, with the aid of a new poison gas referred to as Green X, the Germans had pushed so far forward that they reached the top of Fort Souville, one of the key inner ring forts, from where they could see the spire of Verdun's cathedral. But they never got any further. From that point onwards the French progressively pushed them back until by the end of the battle in December there had been 337,231 French casualties, of which 162,308 were dead or missing, and 337,000 German casualties of which 100,000 were dead or missing. Many of the missing reappear every year, and sadly it is almost impossible now to identify them or work out their nationality from what little is left of their bodies. As a result they are interred in a mass ossuary very close to what is left of Fort Douamont with total disregard for their former enmity. Their remains go into one of several small rooms within the ossuary, the choice of room being dictated by the area upon the battlefield where their remains have been found. Each of the rooms is capped with a large tomb stone in the chapel built above the internment rooms.
Numerous lessons were learnt during the Battle of Verdun, and many flaws and inadequacies were discovered in the design and construction of the forts. Not least of these problems was the fact that areas within the forts could easily get cut off from each other as had happened to such disastrous effect at Fort Vaux. So in early 1917 a series of works referred to as "Travaux 17" were begun, the main job being the construction of a series of deep tunnels connecting all fighting compartments within the forts and the provision of an emergency exit tunnel for the garrison to evacuate should the fort fall. Many of these Travaux 17 tunnels were never completed and it is common to find roofs held up with pit props rotted now to little more than a few black, mouldy, sodden fragments of timber. But in a few very rare cases reinforced concrete tunnels head off for some considerable distance underground. The forts were not abandoned after the war ended in 1918 but were retained as potential defensive works in the unlikely event of a further war with Germany. As history records, "unlikely" did not prove to be reality, and in 1940 the forts were spectacularly bypassed, together with the much more formidable Maginot Line, itself inspired by and modelled upon the Verdun forts, by a rapid, mechanised German army wielding "Blitzkrieg" to devastating effect. To this day the French army has retained almost all of the forts ostensibly for the use of military training, the exceptions being the tourist attractions of Douamont and Vaux. Some of the others are also in private ownership such as Fort de Troyon, Fort Bellrupt and Fort Dugny. Many of the forts retained by the military are seriously razor wired to prevent entry, some have every potential point of entry comprehensively bricked up, one or two like Marre and Belleville are as porous as a sieve...
...and some can be entered with just a little patience and ingenuity!
Recommended reading... Google Earth map with fort locations...
ISBN: 0-14-017041-3 ISBN: 978-1-84908-412-3
Below are picto-button links for the forts we have explored so far. Verdun is such an interesting area we fully intend to add even more to this list! Please select the fort of your choice by clicking the appropriate button...
NB: This part of the site is still under construction at the moment. Forts Belleville, Genicourt, Landrecourt, Marre, Souville, Tavannes, de Bois Bourrus, le Choisel, Sartelles, Saint Michel, Regret, Rozelier and Froideterre are finished pages.
Please continue to check for further fort reports as they come on line.
Click above to return to our main urb-ex site...


text:
41 Abortion Centers Have Closed in the Last Two Years, Coronavirus May Close Even More
Micaiah Bilger Dec 3, 2020 | 11:11AM Washington, DC
Abortion businesses are closing at a rapid pace as abortion rates drop and more women choose life for their babies.
A new report from the Abortion Care Network found that 41 independent abortion facilities (excluding Planned Parenthood) closed in the past two years, and nearly 200 shut down since 2012, Time magazine reports.
Now, five states have only one abortion facility, and the coronavirus could lead to even more closures. All of this is good news for mothers and unborn babies. Women do not need to abort their unborn babies to be healthy or successful, and pro-lifers have been working hard to expand pregnancy and parenting support services to help families in need.
According to the magazine, abortion facilities are struggling financially between increased costs and plummeting revenues. Abortion activists blamed their problems on pro-life laws and efforts as well as the extra equipment and staff needed to handle the coronavirus. Some abortion facilities also said they had to temporarily stop or limit abortions because their abortionists travel from out of state and they were unable to get there due to travel restrictions.
"If things continue or get any worse than they are right now, I don't know how we're gonna do it," Yashica Robinson, the abortionist at the Alabama Women's Center for Reproductive Alternatives in Huntsville, told Time.
Follow LifeNews on the MeWe social media network for the latest pro-life news free from Facebook's censroship!
Robinson said the coronavirus, coupled with pro-life laws in Alabama, have "tremendously" hurt its finances.
When Alabama suspended "elective" medical procedures, including abortions, in late March, the Alabama Women's Center canceled a week of appointments. Even after a federal appeals court ruled that Alabama couldn't block all abortions, Robinson had to file paperwork to justify each abortion she provided for the month the state's emergency public health order was in place, adding time and costs to every appointment.
Most independent abortion clinics across the country are in a similar boat. Keeping clinic doors open during COVID-19 has required spending much more money—on cleaning and personal protective equipment, and on hiring more staff to facilitate social distancing rules that also reduced the number of patients who could be seen.
Most independent abortion facilities are businesses, not non-profits, and they make their money killing unborn babies. During the initial coronavirus shutdowns in March, the Abortion Care Network conducted a survey of its members and found that they expected to lose an average of $50,000 per month.
In June, the pro-abortion group predicted that dozens of abortion facilities may close and four states could be completely abortion free.
The abortion industry has been shrinking for years as the main source of its revenue – killing unborn babies – declines. Statistics from the Centers for Disease Control show abortion rates are at historic lows and fewer unborn babies are being killed in abortions.
According to Operation Rescue, 36 abortion facilities closed while nine opened in 2019. Since 2013, 367 abortion facilities have closed across America.
Recently, medical groups representing more than 30,000 U.S. doctors emphasized that abortions are not "essential" or "urgent," and abortion facilities that continue to operate during the pandemic are being "medically irresponsible." Abortion complications include infections, blood clots, hemorrhaging and an incomplete abortion. Abortion risks include future preterm births, breast cancer, suicide, anxiety/depression, and death. And it is not true that abortions are safer than childbirth.
Abortion facilities do not perform an "essential" medical service. They kill unique, living unborn babies in abortions, and often leave women with life-long physical and/or psychological scars.
Women do not need to abort their unborn babies to be healthy or successful, and real medical facilities exist all across the country to provide true care to mothers and babies, born and unborn. Thousands of pregnancy resource centers provide additional support through free counseling, diapers, baby clothes, cribs, temporary shelter and more.

redpajama_set_name: RedPajamaCommonCrawl


We have an award that has an advance pay (prepaids). Because the advance pay is on Contract Line 0, it is not being pulled into the FFR on line 10a as a receipt. The expenses are on Contract Line 1 and on the run control we are only allowed to select one contract line.
The field 10a should be populated for receipts from prepaids.
2. Go to Contracts' prepaid, Add a prepaid, Change the status to ready.


text:
Rose Festival Promotes Carol Ross to Chief Marketing and Administrative Officer
by Elisa Klein | Jan 11, 2018 | News
PORTLAND Ore. – The Portland Rose Festival has promoted Carol Ross to Chief Marketing and Administrative Officer. The 20-year veteran has held many positions with the Foundation including Director of Sales and Marketing Director. In her new position, Ross will oversee all marketing functions including brand management, advertising, promotions, media sponsorship, and related communications for Festival events and programs.
The Portland Rose Festival has promoted Carol Ross to Chief Marketing and Administrative Officer.
Carol Ross has enjoyed a 20-year career in the non-profit events industry with the Portland Rose Festival Foundation, with duties that encompass marketing, fundraising, ticket sales, group sales, event & program management, business development, and more. During her tenure, the Festival has earned many awards from the International Festivals & Events Association (IFEA), including Best Festival in the World in 2007 and 2011.
In addition to managing marketing and administration for a festival with a 111-year history and a broad range of events, Carol is active in the tourism community as immediate past President of the Oregon Tour & Travel Alliance. When she isn't working, Carol, a Vancouver, Washington resident, enjoys playing flute in her local community band and traveling with her husband and 14 year old daughter.
About the Rose Festival
The Rose Festival produces a broad range of events that burst into bloom on Memorial Day Weekend, attracting nearly one million people from across the city and around the globe, and generating a total estimated economic impact of $65 million for the region's economy. Among the most visible events are Rose Festival CityFair, an urban fair in Gov. Tom McCall Waterfront Park that spans three weekends, and three parades including the Festival's "crown jewel," the all-floral Grand Floral Parade. www.rosefestival.org.
Portland Rose Festival Wins Award for World's Most Environmentally Friendly Festival
PORTLAND Ore. - Portland Rose Festival panned more gold from the International Festival & Events…
Rose Festival and Bank of America Honored By Portland Business Alliance
Portland, OR. Rose Festival COO and 40-year staffer Marilyn Clint, was honored by the Portland Business…
Yellow Brick Rose Dinner Benefits Rose Festival Foundation
Portland, OR. The Portland Rose Festival Foundation's fundraising efforts went "over the rainbow" with $118,000 raised…
Subscribe for FREE Weekly Highlights
NONPROFIT BENEFIT TICKET GIVEAWAYS!
Sign up for our free weekly highlights for the chance to win two tickets terrific nonprofit events! If you "like" us on facebook, or sign up for our weekly news highlights, you'll be entered to win! Sign up today! Look for another ticket giveaway soon! Are you a nonprofit looking to bolster your publicity with facebook and tweets? Email us and we'll run a contest with tickets to your event! [email protected]
Categories Select Category Art Events Features Fundraisers Lifestyle News nonprofit Uncategorized Upcoming Events
Plans Set for New Oregon 2020 Lunar New Year Celebration
Local JDRF Poised to Celebrate "25 Years Strong" in Bold Ways
Girl Scouts of Oregon Work to Educate Scouts about Women's Rights
Coming Up: William Temple House Selected as Christmas Ships Featured Charity
Oregon Humane Society Seeks Heroes to Honor
FALL PREVIEW: Diamonds & Denim Theme Will Sparkle at INCIGHT Gala
$350,000 Grant from Bill & Melinda Gates Helps Portland Based Nonprofit
1,500 Local Volunteers Set to Honor Dr. King's Legacy During Weekend of Service
Arlene Schnitzer Donates Record-Breaking $10 Million to Portland Art Museum
Brides for a Cause Raises Funds for Local Charities With Annual Dress Dash


text:
New tactics used as suspected rapist is deported from UK
Sean O'Neill
June 7 2013, 1:01am, The Times
Scotland Yard passed files to the immigration courtsPhilip Toscano/PA
New tactics will be used to deport foreign criminals after a suspected serial rapist was thrown out of the country.
Lincoln Farquharson was deported last month after police intelligence files were passed to the immigration courts.
The Scotland Yard files, detailing five arrests for rape in as many years, were presented to a tribunal considering his appeal against deportation as an overstayer.
The use of immigration powers to detain and then deport a suspected, but unconvicted, serious offender is a step change in approach designed to show that Britain is not a "soft touch" for alleged criminals who cross borders to try and evade detection. It is also significant because there is a lower standard of proof in the immigration tribunal than a criminal court.


text:
Q: mocking service and running parameterised query in react apollo graphql I'm trying to mock the service as in the docs example http://dev.apollodata.com/tools/graphql-tools/mocking.html#Default-mock-example
I'm exporting my schema with the standard introspection query, building a schema object and using this when trying to run a query as mentioned in the docs.
import * as introspectionResult from "../../graphql/schema.json"
const GRAPHQL_QUERY = `
query eventsFeatured(
  $type: String!,
  $entity_type: String,
  $market__role: String,
  $outcome__odds_rank_unique: Int,
  $limit: Int
) {
  featured(
    type: $type,
    entity_type: $entity_type,
    market__role: $market__role,
    outcome__odds_rank_unique: $outcome__odds_rank_unique,
    limit: $limit
  ) {
    ...FeaturedFragment
    media {
      description
      extralarge
      large
      medium
      preview
      __typename
    }
    event {
      ...EventFragment
      market {
        ...MarketFragment
        outcome {
          ...OutcomeFragment
          media_logo {
            preview
            small
            __typename
          }
          bookie {
            ...BookieFragment
            __typename
          }
          __typename
        }
        __typename
      }
      article {
        ...ArticleFragment
        __typename
      }
      category3 {
        ...AllCategoriesFragment
        __typename
      }
      __typename
    }
    offer {
      id
      name
      conditions
      deeplink
      domain {
        ...EventFragment
        __typename
      }
      __typename
    }
    __typename
  }
}

fragment EventFragment on Event {
  id
  name
  canonicalised_name
  display_name
  date
  date_human
  date_short
  type
  __typename
}

fragment MarketFragment on Market {
  id
  name
  display_name
  canonicalised_name
  type
  role {
    name
    __typename
  }
  __typename
}

fragment OutcomeFragment on Outcome {
  id
  name
  display_name
  canonicalised_name
  odds
  odds_decimal
  odds_rank
  deeplink
  home_or_away
  type
  __typename
}

fragment BookieFragment on Bookie {
  name
  __typename
}

fragment ArticleFragment on BaseArticle {
  title
  body
  excerpt
  author
  date_no_time
  date_stamp
  date_human
  date_short
  date
  __typename
}

fragment AllCategoriesFragment on Category3 {
  ...Category3Fragment
  category2 {
    ...Category2Fragment
    category1 {
      ...Category1Fragment
      __typename
    }
    __typename
  }
  __typename
}

fragment Category1Fragment on Category1 {
  name
  canonicalised_name
  __typename
}

fragment Category2Fragment on Category2 {
  name
  canonicalised_name
  __typename
}

fragment Category3Fragment on Category3 {
  name
  canonicalised_name
  __typename
}

fragment FeaturedFragment on Featured {
  id
  type
  display_order
  __typename
}
`

// this builds our mock apollo schema
const schema = buildClientSchema(introspectionResult)
addMockFunctionsToSchema({ schema })

// execute the supplied apollo query
    graphql(schema, GRAPHQL_QUERY, {
      options: (props) => ({
        variables: {
          type: "IMAGEGRIDHOMEPAGE"
        },
      })})
      .then(graphqlResult => {
.... etc
```

However, I am seeing the following error:

```
{ errors:
       [ GraphQLError {
           message: 'Variable "$type" of required type "String!" was not provided.',
           locations: [Object],
           path: undefined } ] }

It seems that the graphql function does not recognise the standard options object, at least not the variables definitions when used in this context of having a schema object as first arg.  I have tried digging into the source here but my typescript ain't the best - https://github.com/apollographql/react-apollo/blob/master/src/graphql.tsx

A: user error - as can be seen in the docs, the graphql function here is from the base graphql library, not indeed the apollo-react one.

redpajama_set_name: RedPajamaStackExchange


text: require("core-js/modules/es6.typed.uint8-array");

redpajama_set_name: RedPajamaGithub


There are lots of questions that will punctuate your early parenting years. Should I/Shouldn't I? Will they/Won't they? Are they/Are they not?
So long, bingo wings. Hello, uppers arms that Michelle Obama herself would be proud of. If those arms of yours haven't been empty for a while as your wiggling, no longer giggling, offspring has claimed squatters rights, you might just have…a teething baby.
Who needs a full set of Louis Vitton luggage? Not you, you're rocking your very own brand of eye bags and, judging by their size, they will exhaust your full weight allowance. Has sleep eluded you for a while? You might just have…a teething baby.
Leave the Fitbit on the shelf, there is no question as to whether you are getting your 10,000 steps a day in as you pace the house with a screaming infant in tow. If your floor boards are getting creaky, but your bum is looking decidedly firmer, you might just have…a teething baby.
Could your abode make Kim and Aggie gasp? Do Life of Grime episodes feel aspirational? If the sink is full, but the vacuum is not, you might just have…a teething baby.
Are your sheets still clean? They're probably the only thing left in your house that is, right? If your bed has become more an ornamental item than a functional one, congratulations! You, my friend, have…a teething baby.
Luckily Gumigem have you covered. Check out the full range of beautiful jewellery and exciting toys designed to help you through these trying times.


Last week, Trump cancelled his planned trip to the World Economic Forum (WEF meeting), citing the \"intransigence\" of the Democrats on his funding request to build a controversial wall along the US-Mexico border.
By following the strategy of doing a few things well, V.C. Nannapaneni has helped Natco Pharma carve out a space for itself.
Of 30 Sensex stocks, 26 are trading in the red. Sun Pharma (0.82 percent), Bajaj Auto (0.56 percent), Dr Reddy's (0.31 percent) top gainers.
Leading Indian pharmaceutical companies are facing competition in the US from relatively smaller firms back home.


text:
How do cases appear before the Japan Supreme Court?
What are the requirements for maintaining a spousal visa in Japan?
Are prenuptial agreements legal in Japan?
The Supreme Court is the highest court in Japan and the final arbitrator of legal disputes. For a case to get heard by the Supreme Court it must have been litigated, and have reached a judgment, at every lower court without having settled or been dismissed. Therefore, it is quite rare for cases to reach the level of the Supreme Court in Japan.
However, the number of cases that the Supreme Court accepts and decides has been rising almost every year for the past two decades. While the Supreme Court only decided 1,842 cases in 1989, in 2012 the Court heard and ruled on 5,111 cases. In spite of this large increase in case load, the number of cases pending before the court has only increased from 1,084 to 2,171.
If you have questions about litigation in Japan, please contact our office for a legal consultation.
Can a minor marry without the consent of his or her parents?
Is it necessary to file a request for an examination in addition to a patent application in Japan?
Is it possible to cancel a contract with a company that is going through bankruptcy?


Overspeed hockey drills are ones that force players to move their feet faster than what they are comfortable with. When you are looking for a high tempo practice then starting the practice with a series of overspeed drills can be a good idea.
Depending on the type of practice you envision you most likely have a bank of drills that you call upon. I typically like to gear the warm towards the practice so that the warm up will not only get the heart pumping a little bit, but also lead into what we will be working on in that particular session. For example, the day before a tournament or a big game we work on special teams quite a bit. We like to use a warm up in which the players are passing and receiving the puck a couple hundred times.


Buy from our wide selection of Amt750 25 Ghostbuster Ecto for sale online. We feature a huge variety at great prices. Shop Amt750 25 Ghostbuster Ecto now! Featuring Amt750 25 Ghostbuster Ecto for sale at Ebay.com.


SKU: AS381A. Categories: Panorama, British Columbia, Canada, Landscape, Print Art, Region. Tags: Assiniboine, Assiniboine lake, british columbia, canada, lake, Mount Assiniboine.
Feel yourself inside a sudden shining of the sun through rifted clouds.
This panoramic print art photographs a picturesque view of San Pietro Church, Vatican City, and the city of Rome in a calm evening.


text:
Other Guests
Sumiko Saulson
Sumiko Saulson is a cartoonist, science-fiction, fantasy and horror writer, editor of Black Magic Women, Scry of Lust and 100 Black Women in Horror Fiction, author of Solitude, Warmth, The Moon Cried Blood, Happiness and Other Diseases, Somnalia, Insatiable, Ashes and Coffee, and Things That Go Bump In My Head. She wrote and illustrated comics Mauskaveli, Dooky and graphic novels Dreamworlds and Agrippa. She writes for the SEARCH Magazine and the San Francisco Bayview column Writing While Black. The child of African American and Russian-Jewish parents, a native Californian and an Oakland resident who's spent most of their adult life in the San Francisco Bay Area.
www.sumikosaulson.com
Kevin Myrick
Kevin Myrick is both an artist and a technologist. He studied design and entertainment technology at San Francisco State University in the early 1970s, and works today as a theatrical technical director, lighting and multimedia designer, audio engineer and videographer for drama, musical theatre, dance and variety arts productions in the Oakland/San Francisco Bay Area. Kevin was one of the first to combine the emerging technologies of video projection and personal computers, learning computer programming on the fly, to program and project computer generated animated art as part of variety entertainment shows at the famed Filmore Auditorium in San Francisco in 1980. Kevin was a pioneer in community and public access television, wearing many hats as producer, technical director, lighting director, videographer or editor for studios in Atlanta and the Bay Area, for special events and long running shows including The Make Your Own Break Show and Free Enterprise back in the 1980s, and The San Francisco Dance Channel in the early 2000s.
www.synergymoon.com
Kai Leakes
Author Kai Leakes was an imaginative child. Writing didn't seem her path, but with the goal of sharing tales that entertain and add color to a gray literary world has become a part of her DNA. She resides in her hometown St. Louis, MO. Her passion for romance with a touch of darkness and vampires led to her popular series, 'Sin Eaters' Devotion Books and companion novella with additional stories. Kai was featured in the HWA award-nominated horror anthology 'Sycorax's Daughters', and sci-fi anthology, 'The City'. Hopelessly romantic, Kai is releasing, "Love, Trust & Pleasure: A Brothers of Kemet Series.
www.Kaileakes.com
Nikki-Michelle
Nikki-Michelle resides in Metro- Atlanta, Georgia by way of Lexington, Mississippi. Carried by her love of reading, she began writing at the early age of twelve and has been on a journey of "trying" to pen the perfect novel ever since (she's still working on that). Her love of writing and wanting to create fiction with true to life situations are what inspire her to continue to write stories readers will enjoy with characters they can relate to. You can catch her works in the previously released anthologies 'If Only For One Night 1&2,' 'Full Figured 3', and 'Girls From Da Hood 7'. Her full-length works include 'Tell Me No Secrets' and 'Tell Me No Lies' 'All the Things I'm Missing at Home' and the critically acclaimed, Bi-Satisfied & Bi-Sensual. She's also dabbled in the Fantasy genre as she co-authored 'Promised Land' with Essence best-selling author, Brenda Hampton.
https://www.facebook.com/nikkimichellereaders/


Yes, we've survived another year! 2016 may have been filled with odd politics, scary news stories, and celebrity deaths, but The Lego Car Blog continues to amaze us.
Despite this site being as ropey and incompetent as it's always been, in 2016 TLCB smashed through the one million views per year mark! A million a year! For those working behind the scenes here in TLCB Towers, and knowing how out of our depth we really are with the whole running a website thing, this is an unbelievable statistic.
Although we have no idea how the annual view count has surpassed a million it is good news for the online Lego community's vehicle builders, as we hope we're giving recognition to a genre that a few years ago was overlooked by the proper Lego blogs (who have now joined the party in blogging vehicles too).
It's also good news for the various charities and aid organisations that we support. Your views and clicks mean that this site earns a small monthly revenue. As most of our workforce is populated by mythical creatures paid in sugar-coated chocolate confectionary we don't need this, and thus we're able to pass it on to those that do, thanks entirely to your visits.
In 2017 we may explore updating the site to properly accommodate advertisements, as we do now feel a duty to do our best to maximise our earnings, but we'll let you know about this should it happen later in the year.
In the meantime we'll aim to keep bringing you the very best vehicular creations, set reviews, LEGO news, and builder interviews, and we look forward to another year being totally puzzled by the fact that people actually come here to read the inane nonsense we publish.
P.S. The Lego Car Blog is on Facebook now too! Click here to stay in touch via Mark Zuckerberg's bank account.


text:
Spring Comes To the Flatbush Trees
Artist David Eppley will create a gorgeous piece of public art on The Flatbush Trees at Empire Blvd and Flatbush Avenue.
Tim T
Empire Boulevard and Flatbush Avenue
Brooklyn (Lefferts Gardens)
CAMPAIGN ENDS SEPTEMBER 30th! MAKE YOUR CONTRIBUTION NOW!
Artist David Eppley has been chosen to create a piece of public art that utilizes a dilapitaded 35 year-old monument to create an utterly new work. Located at the northern entrance to the Flatbush neighborhood, the project will be immensely visible and intensely symbolic. Local blogger and activist Tim Thomas has championed the project through the past two years, getting the necessary approvals and publicizing the project widely. He now intends to use his community-building skills AND his fundraising acumen (that's his day-job) to bring $10,000 to the project for the cost of materials and equipment.
Almost anyone familiar with central Brooklyn knows the spot well. At the meeting of three major roads - Flatbush Avenue, Ocean Avenue, and Empire Boulevard - one finds oneself across from Prospect Park, the Botanic Garden, the giant Phat Albert's Warehouse building and a peculiar plaza with three green trees made of metal, with bulky cement trunks. The tree-sculpture is dented, rusty, falling apart. It's decay says "you are entering a part of Brooklyn that doesn't care." It's not true of course. That's why we want to tell the REAL story. And it's why we call the project "Spring Arrives for the Flatbush Trees."
Originally meant to welcome visitors and spur economic activity, the so-called "Flatbush Trees" are now a sign of decay and of the blighted decades behind us. A team of relevant stakeholders has come together to approve a vision - and now all we need is money for the materials and we're off. Community Board 9 has unanimously approved the project. The NYC DOT has given its blessing AND $2,000 in seed money. Both the site and proposed art have tremendous symbolic value for the neighborhood as it grapples with the many issues currently facing it.
The building blocks of David Eppley's design will be created in conjunction with neighborhood middle-schoolers. Eppley is already identifying 12-15 young artists to study and work with him to create the 1500 of vinyl hexagon shapes needed to attach to the trees. The material is essentially an industrial vinyl tape favored by Eppley in his installation work. It is removable, so the piece is in fact truly temporary, but it is also highly durable. The tape - Oracal 651 Sign Vinyl - is often used in outdoor signage for this very reason. The kids will be asked to create drawings on the insides of the multi-colored individually made pentagrams, so that each piece is unique. When connected however, the effect is almost of one super- organism (see pictures). Again, the idea is to suggest that spring, or a kind of rebirth, has come to Flatbush. The week-to-ten-day installation phase will require renting a scissor lift, and we will also paint the cement "trunks" of the trees. Included in the design and manufacture phase of the building blocks of the project, essentially extra-curricular "classes" for motivated students, Eppley will have an opportunity to share with local students some of his experiences as a professional artist and teach real-life shop skills to students unavailable in the typical art curriculum. We expect the full diversity of our neighborhood to be tapped throughout, and the signage will bear the names of all who've participated in this community-wide project.
Much of the work has been completed. We have earned the unanimous support of Community Board 9, and have been granted the approval to do the work on the site by the DOT Arterventions program. Elected officials are on board. We have the artist, and he's basically ready to go as soon as we can scrape up the funds to buy the materials, insurance and rent the scaffolding. After running a 45-day campaign, we hope to have the $9K - $10K we need. Popular local blogger Tim Thomas of The Q at Parkside is leading the charge, even creating the video and running the publicity and marketing campaign. He calls this project his "white whale" in honor of Captain Ahab and his obsessive quest. He hopes, however, that this project ends on a more upbeat note for its captain.
The trees say "this is a community that doesn't care, that's down on its luck, and has no future." Nothing could be farther from the truth. Lefferts Gardens is a thriving, incredibly diverse neighborhood experiencing both the good and bad effects of rapid gentrification. Projects like this, wherein the WHOLE community backs a project as uplifting and transformative, have the power to bring people together, people who may not normally have a chance to get to know one another. AND the project uses local middle-schoolers to create the building blocks - 1500 brightly colored hexagons - that will be affixed to the trees. The names of donors and collaborators will appear on a special plaque located on the cement trunks of the trees. It's a feel-good project for crazy times.
Surface Prep Materals and Tools: $1500
Paint: $1500
Vinyl Oracle 651: $8,000
Ladders and Scaffolding: $1500
Insurance: $1200
Signage: $500
Incidentals/Contingency: $1000
SUBTOTAL = $15,200
3rd Party Credit Card Processing Fee (3%) $456
TOTAL TO RAISE = $16,451
UPDATED BUDGET:
TOTAL TO BE DISBURSED = $6,384
Will Miller
The Lovejoys
Susana Millman
Found cash on Flatbush
Pat Glynn
diak
Leah L.
John Dudzinsky
Fleischman's of Flatbush
Buzz and his Dad Jeff
Jane R.
Joanie and Bill Schaffer
Mark D.
Greer & Jonah
in c.
HOUSEOFCAKES
Leon H.
Joseph D. Borrero
Jeff Gross
Barbara Ann Rogers
Pavani T.
Liena Zagare
Roberta W.
Mary Miller
Rina Kleege
Barrie Koegel
Saulnier Family
Arthur G.
Jackie And Stan M.
Skobie
Adrienne R.
Marie Spinney
Kimplicated
MicheleCetera Architect
Jenna Cardinale
Jeffrey Kusama-Hinte
William Stover
Andrew Woodward
Daniel Kristjansson
Jeanne Gerrity
Heimbach S.
Gayle Price
Natalie Beall
Julia and Hannah's mom
Paige B.
Cheryl,Sealey4
Sara Keenan
Miles Farmer
Liz Munch
Ryann & Chris I
Gerard Middleton
Diana L.
Jeffery Welch
Elona P.
Stephen Warner
Bob Marvin
David W
The Hellman-Shamos Family
Agnieszka T.
Distant friend of the hood
Suzanne Cooke
Total Funding Needed: $6,950
$6,950 raised so far
"Urban Patch started with a big idea, to try to make the American inner city better. It is a huge task, but we know the work and change can happen from the ground up, and literally "in our back yards." ioby provided us with time-saving tools, a clean online interface and presence, project support and even outside funding sources. These all helped us to build momentum for our projects and with our supporters. With ioby's help we have exceeded our crowd funding goals, and are on our way toward bringing our ideas to reality and to improve our community."
Justin Moore, Urban Patch Project Leader


Eight More Ways to Augment Your Social Reach!
Home > Blog > Blog > Eight More Ways to Augment Your Social Reach!
It has been a long time talking about the social media and its reach. Personalize, add visuals, initiate a guest blogging program and a lot more about how to go about social media have been talked so far. Let me help you go through some more important facts need to be taken care of while networking on social media outlets.
The first and the foremost thing that matters anyway is your content. Make sure it is the best and distinctive content, that is what people like and share further. Besides, post something new every day keeping your presence on the social media fresh and happening.
Different social media outlets differ in many ways. You need to understand their types and post your content or updates accordingly. For instance, you cannot have similar contents for facebook, twitter and linked in. You are supposed to identify the social media networks features and post accordingly. Not just that even the users, they are also different from each other as in the one on facebbook and the other on twitter or linked in, they share different interests and ideas. You need to be wise here and deal accordingly.
Ask an open-ended question to your fans and followers and let them to chitchat among them and with you. This is how your social presence will get more exposure. Try responding to your fans and followers quite frequently. Besides, according to the facebook's EdgeRank algorithm anyways, the posts that get the most engagement get the most exposure in the News Feed. On your social media outlet, talk about something which is in and the audience want to talk about and encourage the conversation with your own responses, as well.
Engagement is how you can not only build relationship with the users on your network but also those who have not joined you yet. Try interacting with people on social media who aren't yet following you. It could be a retweet, or an entertaining post on facebook or some educational content on any topic on LinkedIn.
Let the people have reasons to follow you. Keep yourself updated within you and with the outside world. Do something interesting and engrossing say posting some wonderful cover photos on facebook or something like that for not only your network but also the new joiners to interact.
The next thing or sorry the second thing that we missed is about the time when you post. Make sure you are posting at a favorable time for your audience. Understand what time of the day your audience is usually active on the social media outlet, try posting your content during that period. Trust me it works like wonders.
You might at a given point of time take them as a waste of time but if you consider these social media apps and features like Vine, Pinterest and facebook ads and so on, you will notice the good results quite often. They might not help with lead generation or any other metric but they keep the audience engaged guiding you to a lead generation. They make social media marketing more valuable you only need to experiment which one works best for you.
This is another wonderful idea to reach more people and promote your content. Create a hashtag for the event you hosted for your joiners to network with each other and prop up your content. They might go ahead and forward it among their peers, friends or followers promoting the event and your company.
We have talked about and will talk about how to go about maximum reach through social media outlets. Updates will come and go however it is you who need to implement those at the right time before it loses its significance. Every new day comes with some new discoveries about this and that but to extract best out of them is up to you. Even you might come across some points that are hidden till date. You never know which research of yours will pop that new point up. Go ahead and share with us for us to benefit with that.


"education esl curriculum jobs in utah"
... Duties 1. Follows the course curriculum outline, prepares and delivers lectures ... Qualifications Master's degree in special education, elementary education, reading, adult education, ESL or closely related field strongly..
... Duties 1. Follows the course curriculum outline, prepares and delivers lectures ... degree in English, Writing/Composition, special education, ESL , adult education strongly preferred. Experience teaching adults ... degree..
Salt Lake City, UT What you'll be doing This individual for this asking position plans and provides instruction to students based on state, district, and school curricula and requirements and based ..
... as a Second Language ( ESL ) to adults in college-level ... adults in college-level (Level IV) ESL courses. Instruction focuses on aquisition ... Responsibilities and Duties 1. Teach..
... Experienced Category: Program Administration Required Education: Masters Job Summary Under the ... facilities, resources, staffing, policies, communication, curriculum, assessment, training, and evaluation necessary ... in English language teaching, tutoring,..
The Adjunct will teach math, reading and/or keyboarding and ten-key to adults enrolled in the College Academic Readiness course in an open-entry/open-exit competency based program. Instruction focuses on skills to prepare ..
... as a Second Language ( ESL ). Acting as the primary ... in the critical areas of curriculum development, recruitment, and retention to ... responsibility for program delivery in..
Salt Lake City, UT What you'll be doing This position plan and provide instruction to students based on state, district, and school curricula and requirements and based on the students social ..


Boot Camp installs Windows support software ( drivers) that let you use features of Apple keyboards in Windows. Here are the latest articles published on Tom' s Hardware. This utility works in two simple steps: 1. USB- IF has a website at The USB- IF announced in September that SuperSpeed USB ( USB 3.
How to Update Windows 8 Drivers. Now that Vista is literally peeking around the corner not that it' s possible for a software to peek , even exist in the physical world but if. Do I need to make a boot disk? All of our device drivers are organized by vendor name by device category so you can easily find drivers you need! When Microsoft released an update to its IntelliType keyboard software to coincide with the launch of Windows Vista, it conspicuously dropped support for one if its keyboard models: the Microsoft Natural Keyboard Pro ( pictured). 8 rmation about products not manufactured by Apple tested by Apple, is provided without recommendation , independent websites not controlled endorsement.
You don' t need the bulky software that comes with your digital puter Repair PC Repair Orlando ~ * ~ FREE~ * ~ Advise. See the latest news roundups , reviews access our tech lect the questions to view the answers. Het was bedoeld om eind uit te komen, als een kleine stap tussen Windows XP en Windows 7 ( tijdelijke namen: Vienna en Blackcomb). When Robert Fripp worked his magic on Windows Vista everyone knew Vista is going to sound different hopefully better.
In Windows 8 swipe up from the bottom right- click anywhere on the desktop. Can I print on CDs and DVDs? I see the message Printer is Offline when I try to print with a USB connection in Windows. Apple drivers windows vista.
Now that Vista is literally peeking around the corner not that it' s possible for a software to peek , but if it were able to peek, even exist in the physical world what would it sound like? In Windows Vista,. All of our device drivers are organized by vendor name by device category so you can easily find drivers.
The only issue is the drivers from the website does not execute right after I download them like they are supposed to. Drivers Update Tool Information This utility contains the only official version for Apple iPad Driver for Windows XP/ 7/ Vista/ 8/ 8.
Windows Vista has been widely criticized by reviewers , an operating system released by Microsoft for consumers on January 30 users. If you don' t, buy it is what we tell everyone. After you have found the right Apple USB device driver, follow these simple instructions to install it. If a language option is given, select your language.
Printing is slow my product stops printing when I try to print from Windows OS X. To download the proper driver please find the category of your Apple device click the link. Windows Vista is net als Windows en Windows XP gebaseerd op de Windows NT- kernel ( kern van het besturingssysteem), en draagt het versienummer Windows NT 6.
Microsoft begon in mei de ontwikkeling van Windows Vista onder de codenaam Longhorn vijf maanden vóór de release van Windows XP. Power off your Apple USB device. I see the message Scanner Not Ready Epson Scan will not start in Windows on my Mac.
Double click the driver download to extract it. Your Tee Support expert will: 1.
Disconnect the device from your computer. Our Backups Superguide is a simple to understand but deeply comprehensive guide. I have the driver installation disc that came with. Apple drivers windows vista.
In Windows 7 click Start - > Control Panel - > Hardware Sound - > Device Manager. If you have ever suffered a lost file corrupt OS turn to APC' s April issue to make sure it never happens again. Driver Scape contains device drivers manually collected from the official websites of manufacturers. 1 & Windows 10 right- click the Start menu select Device Manager.
1/ 10 32- bit and 64- bit versions. Apple drivers windows vista.
Apr 18, · Here are the latest articles published on Tom' s Hardware. I see the message Printer is Offline when I try to print with a USB connection on my Mac. Good news for Natural Keyboard Pro owners: the instructions below describe an easy way to restore full functionality for the keyboard under Windows Vista Windows 7 including.
If there' s a bad hardware driver that is causing Windows to crash during startup, how can you update the driver? Application areas include USB RS232 · Microsoft Windows Pinball also known as 3D Space Cadet Pinball was introduced in Microsoft Plus 95, it then became so popular that it was included in Microsoft Windows NT 4 by p 09, · Listen up, USB Docking Stations, USB Parallel, upgrades of Legacy designs to c 28 all you Boot Camp' in Mac users. Windows Vista is een versie van Microsoft Windows een reeks besturingssystemen ontwikkeld door Microsoft voor het gebruik op pc' s voor zowel thuisgebruik als zakelijk gebruik en de opvolger van Windows XP. This guide shows you how to import pictures from your digital camera to Windows Photo Gallery for Windows Vista.
Windows sees my ipad as a camera is located in " portable devices" s icon shows the driver is corrupted. How to Open Device Manager In Windows 8. Apple drivers windows vista. Orlando Laptop Repair but with the awful changes in Windows 7' s Windows Media Player 12, No boot, Apple Mac Repair Orlando, Laptop Screen, · I was OK with this limitation as a Vista user, Cell Phone v 14, DATA Recovery, PC fix I was inspired to find a way to reprogram the Media button to launch a more sensible music program.
Can' t find Windows drivers for the Apple USB Ethernet adapter? Listen up, all you Boot Camp' in Mac users.
Apple drivers windows vista. Connect securely to your. Connect securely to your computer over the Internet via Tee Support client. If your keyboard works when your Mac is started in OS X but not Windows, try reinstalling Windows support software from Boot Camp Assistant.
Orlando Laptop Repair No boot, DATA Recovery, Apple Mac Repair Orlando, Laptop Screen, PC fix Cell Phone repair. Please enter the email address you would like to send a copy of this page to. ( ive already tryed this) you have 10.
Bonjour is a networking protocol that sends and receives network packets on UDP port 5353. Shop for PC Software for Students, Computer Security, Academic Courseware, Mac software including downloads, Operating Systems, Education & Reference, Small Business Software, Illustration & Design more. This update is recommended for all users to improve the security usability compatibility of your existing Bonjour installation. That is the only source.
If you could not find the exact driver for your hardware device you aren' t sure which driver is right one we have a program that will detect your hardware specifications the latest drivers for your Apple iPhone to keep your Computer up- tuld anyone give me instructions on how i can get the Windows Vista Drivers without the disk? How do I restore the colors in faded photos? Apple IPhone Ipad Drivers I am having trouble with drivers for my iphone, ipad apple tv.
DriverTuner was created to save your time resolving driver problems by providing you with a single Protector Plus Internet Security 64 Bit, automatic unes windows 10 64 bit free download - Apple iTunes ( 64- bit), Apple iTunes ( 64- bit) many more programs. Mar 18 it ran perfectly on these machines but on a generic PC of that era , for some reason, · When Windows ME was released to OEMs such as Tiny there seemed to be problems. When Windows ME was released to OEMs such as Tiny it ran perfectly on these machines but on a generic PC of that era , for some reason there seemed to be problems.
What should I do? Individual drivers may be available freely by manually visiting device manufacturer B RS232 - FTDI designs and supplies USB semiconductor devices with Legacy support including royalty- free drivers. If your keyboard isn' t working. Promptly answer your request determine how Tee Support can help via chat Tee Support client.
Downloads the latest official version of the drivers for the Hardware installs them ers running 64- bit versions of Windows XP Windows Vista can download a compatible version of Bonjour for Windows 1. With it update windows, fix errors, remove cache files, defrag disk, you can clean windows registry download lect the questions to view the answers.
Due to issues with new security features product activation, performance, driver support Windows Vista has been the subject of a number of negative assessments by various groups. Apple drivers windows vista. Keep your system up- to- date and out of trouble. SmartPCFixer™ is a fully featured and easy- to- use system optimization suite.
Want to use use the adapter on another Windows machine? Reconnect the device and power it on. This page contains the list of Apple drivers available for download.
The drivers that bootcamp prompts me to install onto a usb are also for windows 7 only. A driver is software that tells your computer how to recognize graphics card , communicate with a particular device such as a printer network interface card. TechSpot' s library of driver downloads includes the latest graphics card drivers audio, networking, chipset , printers system updates.
How to Install Apple USB Drivers. Automatically identifies your Hardware.
DriverFinder is an advanced driver scanning updating downloading utility for Windows- based PCs. 0) will deliver ten times the data transfer rate of Hi- Speed USB or up to 4. I' m running Windows 7 64bits I need to install Dell 2407wfp drivers.
Use the links on this page to download the latest version of Apple iPhone drivers. All drivers available for download have been scanned by antivirus v 19, · If you have an Intel- based Mac and there' s a PC application you need to use, you can run it using Boot Camp.
You' ll need to provide a copy of Microsoft Windows, but Boot Camp is included in Mac OS X Leopard. Windows Vista is an operating system that was produced by Microsoft for use on personal computers, including home and business desktops, laptops, tablet PCs and media center PCs.
Development was completed on November 8,, and over the following three months, it was released in stages to computer hardware and software manufacturers, business customers and retail B drivers are standardized by an industry standards body called the USB Implementers Forum ( USB- IF) which includes members like Apple, Hewlett- Packard, Intel, Microsoft, Philips and NEC.


text:
Thesis vampire essay
How to start a business presentation example
Writing an executive summary non-profit
Home help with homework Traditional monoclonal antibodies and recombinant antibodies
Traditional monoclonal antibodies and recombinant antibodies
An important development in antibody production followed the discovery that an antibody-forming lymphocyte can be fused with a cancerous bone marrow cell.
Traditional monoclonal antibodies and recombinant antibodies edit ] There are several known formats of recombinant antibodies which are commonly produced. These are the Fab recombinant antibodies, scFv and diabodies. Anti-idiotypic antibodies bind to a paratope of another specific antibody.
Single chain variable fragment scFv [ edit ] scFv is the smallest of the recombinant antibody formats, which is capable of antigen binding.
The two chains are linked by a flexible peptide linker. The sequence is made up of four glycines and a serine [5] and it serves the purpose of stabilization of the fragment. Together they form a stable structure.
That means that they compete with the drug for binding site and have an inhibitory function. Fab fragment antibodies can be used for detection of not bound drugs or free drugs in the serum.
This possibility further broadens the pool of potential target structures. It consists of determining the sequence of the desired product followed by refinement of the codonthen gene synthesis and construct generation. Once the construct is delivered to the laboratory, expression constructs are produced, then they are transferred to a cell culture in the process called transfection and once the cell culture produces the desired recombinant antibody, it is regularly collected, purified and analyzed or used for further experimentation.
The correct fold is essential for functionality of the antibody. Hybridoma[ edit ] Monoclonal antibodies are essential for many therapies applied today in human medicine.
The first successful technology which was robust and led to stable production of desired antibodies was hybridoma technology. The hybridoma cell lines, which produced large quantities of relatively pure and predictable antibodies was first introduced in Despite its indisputable role in scientific discoveries and numerous treatment strategies, the hybridoma technology presents researchers with some obstacles such as ethical issues, potential to lose expression of the target protein or lengthy production and most importantly the development of HAMA in patients as mentioned previously.
Hybridomas are an essential part of the recombinant antibody generation even today as they are still used to produce the monoclonal antibodies, from which the Fab fragments, scFv or somatically fused antibodies create a bispecific antibody.
Recombinant antibodies - reproducibility and specificity | Abcam
This allows for a fast recombinant antibody production and easy manipulation in the laboratory conditions. Both scFv and Fab fragment recombinant antibodies are routinely produced using the antibody phage display. The first one is the so-called non-colinear approach. It works on the principle of heterodimerization of two chains.
Non-colinear approach leads to production of diabodies and recombinant antibodies, which combine two specificities. The second approach is called colinear and it described the process of fusion of two different scFv with a biologically active protein.
Their specificity and low immunogenicity make them a great alternative to traditional forms of treatment, increasing the accuracy of targeting specific molecules and avoiding adverse side effects.
Choose your preferred view mode
Recombinant antibodies have been explored as a treatment for cancer[21] HIV[22] herpes simplex virus HSV [20] and more. ScFv have been a part of the highly promising therapeutic approach of universal chimeric antigen receptors uniCAR technology, which shows promising results.
The scFv are part of the technology in the form of target moduleswhich direct the immune response to specific cancer cells, expressing the target antigen. Specific recombinant antibodies are designed to bind with to surface heparin sulphate proteoglycan HSPwhich complicates or even disables the entry of the HSV into the host cell.
This is a method which significantly decreases the severity of HSV infection. In case of rabies infection, which is only treatable shortly after exposure, accurate and precise diagnosis is vital for survival of the patient.
In comparison to commercially produced and commonly available antibodies, the recombinant antibodies are cheaper to produce and more accurate in determining the infection.
Another advantage of the recombinant antibody is the potential application as a neutralizing antibody as part of the subsequent treatment.
As mentioned previously the recombinant antibodies and especially those, which have been developed in phage display are highly specific, have great pharmacokinetics and could be used in wide range of treatments.
However, it is important to realize that it is not expected or desired for the recombinant antibodies created in phage display to completely replace the hybridoma antibody production but rather to complement it. The first one is the complete elimination of ethical issues because there is no need for animal immunization.
Researchers have managed to produce antibodies carrying no other activity than the antigen binding.Recombinant Antibody Technology for the Production of Antibodies Without the Use of Animals metin2sell.com is a website dedicated to advancing non-animal methods of toxicity testing.
Monoclonal antibody, antibody produced artificially through genetic engineering and related techniques. Production of monoclonal antibodies was one of the most important techniques of biotechnology to emerge during the last quarter of the 20th century.
A single-domain antibody (sdAb) is an antibody fragment consisting of a single monomeric variable antibody metin2sell.com a whole antibody, it is able to bind selectively to a specific metin2sell.com a molecular weight of only 12–15 kDa, single-domain antibodies are much smaller than common antibodies (– kDa) which are composed of two heavy protein chains and two light chains, and even.
1. Introduction. Recombinant therapeutic proteins (monoclonal antibodies, in particular) are usually produced by genetically-engineered prokaryotic or eukaryotic host . Monoclonal antibodies (mAbs) are highly complex recombinant proteins used successfully as therapeutics in many disease indications.
Myriad analytical techniques are required to characterize and control the quality of these molecules during their clinical development and commercial production.
Business plan template nzte beachheads
A description of the thin red line the 1964 black and white picture version
Hsm week 2
Ole miss honors college essay
A short guide to writing about art by sylvan barnet summary
How to write a vlookup formula in excel
Moral philosophy in the business world
Essay on jinn
Writing a personal reference letter for a coworker winked
Doctorial dissertation
Issue and theory ms washburn s strengths
monoclonal antibody | Definition, Hybridoma, & Human Monoclonal Antibody | metin2sell.com


text:
Natural Resources Police team with USMC Reserve
Delaware News Desk
Toys for Tots program
The Delaware Department of Natural Resources and Environmental Control Natural Resources Police units from Delaware State Parks, the Division of Fish & Wildlife and the Environmental Crimes Unit have teamed up with the U.S. Marine Corps Reserve Toys for Tots program to provide toys for children in local communities for the holidays.
The U.S. Marine Corps Reserve Toys for Tots collects new, unwrapped toys suitable for boys and girls of all ages, and distributes those toys as Christmas gifts to less fortunate children in communities nationwide.
Toys will be accepted through Dec. 12 at the following drop-off locations:
— All Delaware State Park offices statewide, including the Brandywine Zoo, from 8 a.m. to 4p.m. Mondays through Fridays;
— Natural Resources Police office in Sussex County, 23530 Campbell Circle, Georgetown, from 8:30 a.m. to 4 p.m. Mondays through Fridays;
— Environmental Crimes Unit offices at 715 Grantham Lane, New Castle, and 97 Commerce Way, Suite 106, Dover, from 8 a.m. to 4:30 p.m. Mondays through Fridays;
— DNREC Richardson & Robbins Building, 89 Kings Highway, Dover, from 8 a.m. to 4 p.m. Mondays through Fridays; and various locations and events throughout the state attended by Natural Resources Police officers.
For more information, or for the dates and locations of upcoming events where toys can be donated, contact andrew.manning@delaware.gov or 855-2113, brooke.mitchell@delaware.gov or 739-9913, or rebecca.schuman@delaware.gov, or 739-9401.
Submit an Announcement or Memorial
Appoquinimink Library
Corbit-Calloway Memorial Library
The Everett Theatre
Middletown Transcript ~ 24 W. Main St., Middletown, DE 19709 ~ Do Not Sell My Personal Information ~ Cookie Policy ~ Do Not Sell My Personal Information ~ Privacy Policy ~ Terms Of Service ~ Your California Privacy Rights / Privacy Policy


The Partners of Condon & Forsyth LLP are pleased to announce that Evan Kwarta and Allison Surcouf have been elected Partners in the firm effective January 1, 2018.
Evan's practice encompasses all aspects of aviation, mass tort, and commercial litigation. Evan was a member of the team representing American Airlines that settled all property damage litigation arising from the September 11, 2001 terrorist attacks. Evan was also part of the team representing Colgan Air in wrongful death litigation in connection with the February 2009 crash of Flight 3407.
Allison specializes in aviation litigation and alternative dispute resolution. She has trial and appellate experience in litigation involving aviation, product liability and employment issues, as well as general commercial and civil matters. Allison has successfully handled trials in state and federal courts and secured dismissals in favor of the firm's airline, aerospace, and manufacturing clients. She also has represented the firm's clients before administrative agencies and in regulatory matters.


Join Zane's mission to infiltrate evil Garmadon's Volca Lair and take on the shark army, with this exciting THE LEGO NINJAGO MOVIE set. The base includes a minifigure-launch function at the tip of the volca, Garmadon's throne room, computer lab with a mini piranha mech prototype, construction zone with an exploding wall function and rotating crane to lift the included shark figure, plus a drone launch pad. This building toy also includes 5 minifigures.


Your admission gives you with a driving and garden description guide to all tour web sites. The greenhouses, some dating back to the early 20th century have been in a very negative state of repair but the plants have been maintained to an incredibly higher standard with what is clearly a large level of staff commitment, and at times better collections on display than at Kew fairly honestly.
Some thing about the concept of utilizing this restricted supply of this ancient relic just to enhance my little veggie garden patch does not float my boat. Great!!, In no way thought there could be so several folks with Deer in their garden so to enhance these deterrents.
Every little thing you encounter in the garden has been hand-picked and meticulously placed to capture the 5 components and the power of Qi. Haupt has ensured not only that her garden was developed, but that it would flourish and stay a haven for guests to the Smithsonian Institution and harried urban dwellers in the Washington, D.C. location. It really is listed beneath non-fiction, simply because it is this Connecticut gardener's accurate life account of his adventures. The Garden comprises almost three acres and its functions include a Gothic fountain, flower beds, lawns, an Italianate terrace, 'Medieval' wall, summer-residence, woodland walkways and a rustic bridge. Also the owners adore to watch the ever-present hummingbirds zoom around the garden. Let's take a rapid appear at the herbs developing in the garden close to the home filled with fast and tasty fruits and vegetables and fragrant, colorful flowers. I've attempted almost every thing to stop the deer and rabbits from ruining my garden.
Numerous years ago I would usually have a couple of times during the season in which I would see a number of monarchs in my garden and have 20 or so caterpillars early in the spring and again in the late summer season / early fall. You can complement your bridge with a cottage garden of hollyhocks and other old-fashioned plants, grasses, an elegant weeping tree, or easy-care perennials to add to the effect you want. In contrast to me, my brother and his girlfriend structure their garden in one of Southern California's inland valleys about wildflower seeds. But 'Gardening Leave' is a great opportunity to find that perform/not-function life balance.
My garden has been certified for a number of years as a Monarch Waystation by means of Monarch Watch – an organization committed to producing, conserving and guarding milkweed / monarch habitats. December 2015: A new image of the Garden Bridge in winter illustrated what planting will appear like in the coldest months of the year. At the University of Sheffield, James Hitchmough 's function is revolutionary and complete of enormous potential Nigel Dunnett at Sheffield is a green roof, rain garden and sustainable planting guru. March 2016: As winter came to an finish, a new image brought to life what the Garden Bridge will look like in Spring. With our help, a single dedicated resident identified a neighborhood, land and funding to commence a brand new neighborhood garden.


EGR OEM Style Fender flares are designed to match the original look of your truck or SUV. They can easily be painted to match the color of your vehicle. EGR Fender Flares also help protect your vehicle from road grime and debris.
EGR OEM Style Fender Flares are made from UV protected, OEM approved acrylic material which is built to last. Your fender flares are custom designed to fit your vehicle, and are shaped to fit the body lines of your vehicle. Easy to install with automotive-grade adhesive, no drilling or cutting. They come in a flat black finish, or you can paint them to match your vehicle.
Available in front sets, rear sets, or a 4-wheel set. Your EGR OEM Style Fender Flares are backed by a Lifetime warranty.


BPS Spinnerbaits Lazer Eye - Double Willow 1/2 Oz.
Home>Hardbaits>Spinnerbaits - Buzzbaits>BPS Spinnerbaits Lazer Eye - Double Willow 1/2 Oz.
Tournament quality baits at Bass Pro Prices! Made with ball bearing swivels, Eagle Claw® Lazer Sharp® hooks, stainless steel wire, chip-resistant paint, 40-strand silicone skirts with metal flake and exclusive reflective Lazer Eyes.
Weight...: 1/2 Oz. / 14,18 gr.


I'm being ask to write a program Currency Converts arbitrary amount for one foreign country to US dollar - user can NOT select which currency - only the amount. Program to display message telling the user what currency - What does he want ?
Is he saying this choose from a list by the amount ??


text:
Q: EF migrations need default ctor, however, I don't know the connection string? EF code first migrations require me to put a default constructor on my DbContext class, this requires me to know the exact connection string - however, I don't know the connection string yet.
My context and the entities reside in a MyProject.Data assembly with no information about the actual database whatsoever. The connection string is in the MyProject.Executable's app.config file. Still I want to put all the migrations into the MyProject.Data project, because that is where they belong.
Is there any way to do EF migrations without having a default CTOR, etc.?

A: If the connectionstring is in the app.config/Web.config of your main project (the one you will be building), you can use ConfigurationManager.ConnectionStrings to retrieve them.
If you are wondering how it will work if it's in a different project: This will only be executed at runtime. At runtime, your projects have been compiled into one big application, and everything listens to the same app.config/Web.config file (the one that was in your startup project when you built it).
From the link:
var connectionString =
        ConfigurationManager.ConnectionStrings["WingtipToys"].ConnectionString;

using (var connection = new SqlConnection(connectionString))
 {
   //...
 }

The same applies for any constructor where you need to know the connectionstring, like your DBContext.
According to this SO answer, you only need to pass the name of your connectionstring, so that means you don't even need to use ConfigurationManager.
From the linked answer:
After reading the docs, I have to pass the name of the connection string instead:

var db = new NerdDinners("NerdDinnerDb");

A: You can refer to the name of connection string placed in your default start up project. This is why parameter of DbContext constructor is nameOrConnectionString.
public class MyContext : DbContext
{
    public MyContext()
         : base("Name=NameOfConnectionString")
    {
    }
}


In July 2018 HMRC proposed new legislation to limit the circumstances in which rent-a-room relief can be claimed. When and how will the new restriction apply?
Rent-a-room relief (RARR) allows anyone who lets all or part of their homes, say to a lodger, to receive tax free the lesser of £7,500 or £3,750 for each joint owner of the property, per year. The exemption applies to rents and related payments, e.g. money for laundry services. HMRC now wants to place further restrictions on RARR.
RARR is increasingly being claimed by people who let their homes while temporarily absent from them, e.g. where the property is near to a major sporting venue, such as Wimbledon. It also happens where individuals temporarily have to live elsewhere for, say, work purposes. HMRC says that this wasn't the purpose of RARR; it was really aimed at people who took in lodgers.
New legislation will change the RARR rules so that from 6 April 2019 it can only be claimed in respect of periods where occupation of the property as "sleeping accommodation" overlaps "wholly or partly" with the period of letting. This means it will still be available to Airbnb type letting as long as you stay in part of your home for at least some of the time each tenant is in occupation.
Tip. Where RARR doesn't apply because of the changes to the rules, you will be entitled to claim the property allowance (PA). This allows a maximum of £1,000 tax-free income.
The draft legislation was subject to consultation until 31 August 2018. Details of the outcome and the final proposed version on the new rules won't be available until the Finance Bill 2019 is published in December 2018. We'll let you know if this includes any changes to the current proposal, although we don't anticipate that there will be anything significant.
From 6 April 2019 rent-a-room relief won't be allowed unless you occupy part of your home for some or all of that time that you're letting another part of. The £1,000 tax-free property allowance will be available instead.


With its sinuous, classical line, the Giac collection is named after Giacometti, its inspiration. The collection provides an elegant and sleek seating option that appears delicate but has incredible gravitas.
Black, Satin Nickel, White Bronze, Oil-Rubbed Bronze, or Champagne Bronze. COL or COM. 27 sqft / 1.5 yards.


text:
Q: Cauchy Schwarz inequality? Let $f_1,f_2$ be two functions on $L^2(\mathbb R^2/(2\pi \mathbb Z^2))$ that depend analytically on a parameter $t$.
Is the following expression then always positive?
$$G(f_1,f_2)(t) = \Vert \dot{f}_1 \Vert^2_2 \Vert f_2 \Vert^2_2 + \Vert \dot{f}_2 \Vert^2_2 \Vert f_1 \Vert^2_2 + 2 \Re((f_1,\dot{f}_1) (\dot{f}_2,f_1) -(\dot{f}_2,\dot{f}_1) (f_1,f_2))  -\vert (\dot{f}_1,f_2) \vert^2 - \vert(f_1,\dot{f}_2)\vert^2?$$
where $\dot{f}(t)=f'(t).$
It is clear that $$\Vert \dot{f}_1 \Vert^2_2 \Vert f_2 \Vert^2_2 + \Vert \dot{f}_2 \Vert^2_2 \Vert f_1 \Vert^2_2 \ge \vert (\dot{f}_1,f_2) \vert^2 +\vert(f_1,\dot{f}_2)\vert^2$$
by the Cauchy Schwarz inequality, but it is unclear to me what the situation is for the full expression.


Adelphi specialises in Somali desktop publishing (DTP) and typesetting.
All Somali desktop publishing is handled in-house and includes the production of brochures, packaging, manuals and other printed materials.
Adelphi has its own in-house desktop publishing studio providing Somali translations and Somali desktop publishing (DTP). All our Somali desktop publishing is handled in-house and carried out by our own experienced typesetters. We have been producing Somali printed materials for over 20 years including corporate brochures, packaging, business cards, posters and manuals, not just in Somali but also in over 100 other languages.
Adelphi offers a complete Somali desktop publishing and typesetting localisation service to its customers.
Although written in the Latin alphabet Somali is very long when compared to English.
Example: Good luck in Somali is Guul ayaan kuu rajaynayaa.


text:
Music Theatre Bristol presents RENT
One of the most famous musicals ever written, RENT is a rock musical set in late 80's New York. It follows a group of young artists living with the effects of AIDS, poverty and the drug crisis, all struggling to get by, yet holds out hope with their redemptive love for one another. RENT is lively and joyful, yet heart wrenching. Winner of the Tony Award for Best Musical and the Pulitzer Prize for Drama, Rent has become a pop cultural phenomenon with songs that rock and a story that resonates with audiences of all ages Book, Music and Lyrics by Jonathan Larson. Original concept and Additional Lyrics by Billy Aronson, Musical Arrangements by Steve Skinner, Music Supervision and Additional Arrangements by Tim Weil. Dramaturg - Lynn Thomson. RENT was originally produced in New York by New York Theatre Workshop and on Broadway by Jeffrey Seller, Kevin McCollum, Allan S. Gordon and New York Theatre Workshop.
Contains strong language and sex references.
Directed by Julia Zervos, asst. Phoebe Campbell
Produced by Benjamin Orr, Naomi Adedokun
Musical Direction Fintan Kealy, James Ladds
Written By Jonathon Larson
Choreography Monica Young


Hotels Close To Carleton University Ottawa Ontario is free HD wallpaper. This wallpaper was upload at April 20, 2019 upload by admin in .You can download it in your computer by clicking resolution image in Download by size:. Don't forget to rate and comment if you interest with this wallpaper.


text:
I love dogs - it's their owners I dislike
Opinion // Outlook
I love dogs — it's their owners I dislike
DAN PARKS
I was jogging on the Glover Archbold Trail in the District of Columbia recently when a woman appeared on the path ahead, walking toward me with two large dogs, neither on a leash. One, a shaggy collie mix, lumbered lazily along and stuck close to its owner. But the other dog, a Doberman pinscher, bounded up the trail, all wiry energy, heading straight for me. It wasn't growling or barking — but it wasn't wagging its tail, either. The woman yelled, "Get back here!" but made no real attempt to restrain it.
When the Doberman was about three feet from me, it jumped up toward my face. Startled, I raised my left arm, and the dog bit lightly on my wrist. Not enough to hurt or break the skin, but enough to make me wish I'd picked a different route. Then it let go and trotted on down the trail.
I jogged past the woman, glaring at her. She shook her head a little and offered a not-very-sincere-sounding "Sorry." She was smiling slightly, apparently assuming I found this incident as harmless and amusing as she did.
But I didn't. During the last couple of miles of my run, I grew angrier by the minute. Not at the dog, but at the woman. Was it really possible for her to be so dense about how threatening her animal could seem to a stranger?
I can't imagine that I was the first person her Doberman had menaced. Yet it seemed she had concluded that granting her pets the joy of running free was more important than other people's right to use the park without feeling threatened. Maybe she had even deluded herself into thinking her dog's actions were quirky and cute.
Well, dog lovers, brace yourselves for a little harsh reality: Your pooches aren't as lovable to everybody else as they are to you. I know this is a crushing thought, but there are lots of people who don't enjoy being licked, sniffed, nipped or otherwise greeted by your four-legged friends.
Those who do want to get to know your pets will make it obvious. They'll give a whistle and say, "Here, boy!" I see it all the time — I even do it myself on occasion. But for the sake of harmony between the dog and non-dog people, can you please not assume that everybody's OK with having Fido in their faces?
Don't dismiss this as the rant of a dog hater. You couldn't be more wrong. I grew up in a small town in Wisconsin. My family always had one or two dogs and a couple of cats. We didn't pull up a chair at the dinner table for them, and I guarantee that none attended a day spa for pets. But they all lived comfortable lives and enjoyed plenty of affection.
My favorite was an adorable beagle who lived to 17 and often seemed to be my best friend in the world. When my childhood companion died several years ago, I was crushed.
But let's be realistic: No pet, not even my beloved beagle, is more important than a person, and pets don't belong in certain places. I know lots of responsible pet owners who feel the same way. But too many people, particularly in urban areas, seem to have lost a piece of their minds when it comes to their pets.
I'm stunned to see how many people insist on keeping dogs — sometimes large dogs, sometimes multiple dogs — in small urban spaces. I live alone in a one-bedroom condo, and as much as I'd love to have another beagle, I wouldn't want to lock a dog in my place for eight or 10 hours every day. I think it would be cruel. Not to mention messy.
Which brings me to those who balk at the most basic responsibility of owning a pet. You know what I mean. Sure, picking up dog doo-doo is a demeaning task, but hey — if you insist on keeping a pair of greyhounds in the midst of 8 million people, there's a price to be paid. In densely populated areas, cleaning up after your pet isn't just polite, it's a public health matter (besides often being the law). And every time a non-dog person soils a pair of shoes on what Fluffy left behind, you're feeding all that anti-dog
fervor.
Even more troubling are owners like the woman in the park, who are oblivious to how frightening their pets can be. I wasn't afraid of her Doberman, because I grew up around dogs and sensed from its body language that it probably wasn't vicious. But if that dog had gone after a 3-year-old in the same way, the incident could have been downright ugly.
And what is the deal with the pit bull rescue crowd?
Perhaps pit bulls really are gentle by nature, as their owners claim. Maybe it's true that only bad people make dogs do bad things. But even if only bad people would use explosives to hurt other people, for instance, we wouldn't start making dynamite available at the local hardware store assuming that only demolition experts would purchase it, would we?
Same with pit bulls. These dogs aren't suitable as domestic pets, so they shouldn't be promoted as such.
All these problems and others seem to arise from the growing phenomenon of people viewing pets as mini-humans.
Animals don't need the same things from life as humans, and their rights fall somewhere below ours. Trust me — your dogs are cool with that, as long as you treat them with kindness and dignity. (Hint: Dignity does not equal a dog wearing leg warmers.)
You and your pet will both be happier if you can come to terms with that. And if you use a little common sense when taking your pets for a stroll, the rest of us will be happier, too.
But for those of you who insist that your pooches be allowed to stretch their legs and enjoy the wonders of the world unfettered by pesky laws and the courtesies that should apply when you share small spaces with lots of people, may I humbly suggest that you look into a house in the country. With a 10-acre lot.
Parks, economics and finance editor of Congressional Quarterly, lives in Arlington, Va.


When you're in your thirties and mid-existential crisis, every day feels like going through adrenaline withdrawals and every moment feels like you're seeking your next fix. And that's because there is nothing like a near-death experience to make you feel alive. Fear is the reminder that you're at the mercy of the things that occur to you, and your only control is the way you choose to experience them. When your addiction to feeling alive makes you a junkie, then you must know there's an endless supply available at The Miami-Dade County Youth Fair[i].
Eat – When you're a kid, all you plan for are the rides. You grow up, your priorities change. Plan accordingly. A food court on steroids, at The Fair, food choices abound. My recommendations are the Arepas, funnel cake bacon-on-a-stick, Mexican seasoned corn-on-the cob, and the massive turkey legs.
Drink – The perks of being an adult, are the libations. So, indulge. Whether at Beer Haven, the largest mobile brewery in the world, or Opa Opa Saloon, a full bar serving craft beer, slushy margaritas, and a variety of wine and Sangria. You cannot say you've truly lived until you've had the chocolate peanut butter beer or the watermelon ale; both light, fruity, and refreshing.
Refresh – You couldn't get me indoors when I was an inexperience pre-teen with priorities out of whack. Now, with hormonal struggles of a different nature, and a body that at times won't keep up, I have learned to pace myself. And I don't know if I should blame my age or climate change, but I feel like I get 98% more hot when I'm outside now than I ever have before. So, don't judge me if walking in 85 degree weather seems unappealing. My solution – go indoors. Walk through The Marketplace and enjoy the exhibitions or sit in the air conditioned Fuchs pavilion and enjoy a show. Watch the musical legends that are The Village People and Willy Chirino perform. After all, all live entertainment is free and included with admission.
Now, I am not discarding the actual childish experiences altogether. On the contrary, be frivolous. Ride as many of the nearly 100 thrilling rides as your wiser (older), more sensitive body will allow. But do so mindfully, close your eyes and as your face smashes through the wind, realize how fickle life can be. Dress up and plan romantic moments like kissing in front of the Ferris wheel. Be completely contemplative. As you enjoy watching the sun set over Miami while you're on the Sky Ride, realize that making it in your thirties is no easy feat and each small moment should be celebrated with equal parts fear and excitement.
[i] Boasting to be 35 years my senior, The Miami-Dade County Youth Fair & Exposition is the largest charity event in South Florida. For 65 years, The Youth Fair, a non-profit association, has been dedicated to promoting education and has presented well above $10 million to the Miami-Dade community.
I have to go the Fair before its done!


Issue 68 features Kurt Simonson, Cara Harman, Noah Addis, and Charlotte Strode.
Leo Hsu reviews "On a Wet Bough" by Keliy Anderson-Staley.
It's November, and I find myself reflecting back on all of the terrific work Fraction has shown this year. I am really proud to have added so many talented artists to the Fraction family. This issue is a great example.
I had the pleasure of meeting Noah Addis at Filter this year. His work and his attitude are both energized, and it's work like Future Cities that I feel must be seen by as many people as possible. While I try to keep all personal political statements away from Fraction, they way we are treating the Earth and the way some people have to live is pretty awful.
I met Kurt Simonson several years ago when I first saw his Northwoods Journal projects, which was featured in Issue 32. Kurt continues to evolve as an artist and begins to open himself up with this new and still in-progress project I Love You, Man. I am really excited to show this work here and to see where it goes.
In July 2013, I worked with Charlotte Strode at a Flash Powder Retreat, and I've been a fan of her and Songs from the Road ever since. Her work is quiet and beautiful and heartfelt. I would encourage you to really spend some time with this work and let the emotion of it sink it.
Cara Harman is an artist that I have recently discovered (for myself). The images that make up Lost Things Found Space now haunt me as much as I think they haunt her.
Also to note, the 7th Annual Fraction Holiday Print Sale will kick off on Monday, November 24. If you're not on the Fraction email list, please consider it. Sign up here and get notified first!
As always, thanks for your support of Fraction and its artists.


Drink tea not coffee. Coffee is great for a sudden burst of energy propping you up during late nights on CAD but beware! The caffeine in coffee gets into your blood quickly giving you an initial rush that, if sustained, will cause your body to burn out. A strong mug of tea has a similar amount of caffeine but it's released more gradually keeping you focused but calm for longer. Tea is also an antioxidant, relieves tension and is less of a faff to make.
Draw lots and draw by hand. Drawing isn't just a way of communicating with others it's a way of thinking. From Le Corbusier's messy sketches to Zaha Hadid's vast paintings, drawing is essential to the practice, culture and progress of architecture.
When making models use a sharp scalpel. Scalpel blades are not cheap when bought from craft shops and blunt quickly but don't be tempted to cut your costs by using dull blades. If you slip and cut yourself a blunt blade will give you a messy and painful wound that takes ages to heal. However, if you cut yourself with a fresh blade the wound will be cleaner, will heal faster and if serious will be easier for a medic to dress. You can save money buying scalpel blades online in bulk.
Pin-up straight. Sounds like a no brainer but it is amazing how many first year pin-ups lead to hastily taping drawings to walls wonkily. Even a rough sketch on torn butter paper deserves better than that. Invest in a huge box of pins and line up your drawings with each other as well as the wall.
Your tutors are an invaluable source of wisdom and ideas – use them lots. Don't just wait for your weekly tutorial to roll around; actively seek out the advice, opinions and critique of your school's faculty. Knock on their doors, email them, chase them through hallways, lie in wait near their office. Do whatever it takes.
Your tutors' knowledge only goes so far. Intelligence, experience and damning criticisms they may have, a monopoly on the truth they do not. Sometimes the best tutor is the one who tells you to design the blue house so you become even more determined to design the red one. Listen carefully and understand their point of view but take what your tutors say with a pinch of salt.
Power nap with caution. By the end of your time at architecture school your friends will have experimented with every sleeping cycle under the sun. Some will swear that 20 minutes sleep is more refreshing than 40. Others will switch to sleeping in four-hour bursts alone. You'll see students making beds beneath their desks in studio or going 80 hours without sleep. There may well be times when you have to work late but the truth is that you're never going to produce great work when knackered – far better to stay focused and productive during normal working hours than to let your course steal your sleep and productivity. Keep a regular daily timetable. Give yourself firm finishing times in the evening and stick to them.
Subscribe to a journal. Regularly reading an architecture magazine is an invaluable source of inspiration. A good journal should challenge you to think deeply about architecture and its relationship to the wider world but should also be a thoroughly good read and beautifully designed. From a tutor's point of view the difference between students who are regularly reading articles or short essays in architectural journals and those who are not is dramatic. Luckily many architecture journals have great student deals on at the moment if you can find them. Subscribe to the AR today.
University grading systems are odd and architecture marking is brutal. Students who've been at the top of their class all their lives arrive at architecture school and find themselves struggling to get middle-of-the-road marks. Take heart. Your final grade is far less important than the skills and portfolio you'll build on your way to it. The line up of internationally acclaimed architects is littered with designers who did badly at architecture school, dropped out or didn't study architecture at all.
Eat delicious food. With so many deadlines it can be tempting to buy ready meals and takeaways rather than waste time cooking. This is a false economy. A good diet gives you more energy through the day, keeps you healthy and prepares you for a life of wearing slinky black turtlenecks. If you're not the next Bompas and Parr already learn to cook some simple meals in large quantities that will keep for a few days – soups, stews, pastas and pastries.
Explore. Travel often with an open mind. Understand cultures and traditions different to your own. That doesn't necessarily mean jet setting around the world or hitchhiking to Morocco. Wherever you are based there will be a myriad of unfamiliar communities and landscapes within easy reach. Get to know the country you are studying in better – even if you grew up there.