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Trending: Red Wings outduel Senators in shootout win, 3-2
Larkin paces victory with a goal in regulation and the shootout winner
by Arthur J. Regner and Dana Wakiji @ArthurJRegner and @Dwakiji / DetroitRedWings.com
DETROIT -- It was quite a clash between the Red Wings and the Ottawa Senators Friday night at Little Caesars Arena.
In a game which had a little bit of everything, including the Red Wings squandering a 2-0 lead, Mike Green hitting the goal post when facing a wide open net during a mad overtime scramble in front of the Ottawa goal and Detroit killing off a full two-minute penalty in OT, but the Wings managed to maneuver through the adversity to defeat the Ottawa Senators in a shootout, 3-2, in front of an enthusiastic crowd.
It was Detroit's second straight victory and extended Detroit's home winning streak to a season-best three games.
All-Star Tyler Bertuzzi and Dylan Larkin (power play), in an end-to-end rush, scored for the Red Wings. Larkin also scored the only goal in the shootout to give the Red Wings the win.
Jonathan Bernier (10-12-2) picked up the victory for the Wings. He stopped 29 of the 31 shots he faced for a .935 save percentage.
His counterpoint in net, Ottawa's Marcus Hogberg (1-2-3), also played well, especially in overtime when the Wings were storming all over the Sens' goal mouth. Hogberg made 26 saves out of the 28 shots the Wings fired for a save percentage of .929.
Detroit (12-30-3) will try to extend its two-game winning streak and its three-game home winning streak on Sunday when they host the Buffalo Sabres. The face-off on Sunday is slated for 5 p.m.
The Ottawa Senators (16-23-5), winless in their last six games (0-5-1), will play the second game of a back-to-back when they square off versus the Montreal Canadiens Saturday in Ottawa. The game against the Canadiens will open up a five-game homestand for the Sens.
Tweet from @DetroitRedWings: Let's keep it goin'. pic.twitter.com/PZTFl0ZS9L
1. Dylan Larkin: There is a lot resting on Larkin's young shoulders this season as Detroit's No. 1 center. The team needs him to be good both offensively and defensively, often playing against the other teams' top players. While Larkin isn't on the same offensive pace he was last season, he still is someone who can create something on his own. At 5:32 of the second, with the Wings on the power play, Larkin did just that, carrying the puck into the offensive zone, zipping around a few Senators on his way to the net and then beating Hogberg stick-side. It was Larkin's 11th goal of the season and 99th of his career. Filip Hronek and Bertuzzi got the assists. The goal extended Larkin's point streak to five games, tying him with Anthony Mantha (Nov. 6-14) and Bertuzzi (Dec. 14-22) for longest point streak by a Wing this season. Larkin has seven points (3-4-7) in his last seven contests. When nothing was decided throughout the third period and overtime, Larkin was the second player to go in the shootout and scored the only goal. It was only his second career shootout goal in 13 tries. Larkin finished with 26 shifts for 22:34, was tied with Filip Zadina for a team-high four shots, had one giveaway, was 7-for-20 in face-offs and was plus-1.
Tweet from @DetroitRedWings: Dylan Larkin.WHAT A BEAUTY! #LGRW pic.twitter.com/q5A2hB9FXu
Quotable: "I saw an opening there. It's nice getting the puck like that when most of their players are standing still. I always watch Val Filppula head fake the guy, so I head-faked the first guy like him. I used my speed to go around the defenseman and it kind of just opened up. I knew I was cutting to the far post and trying to get across there. It was a good play by the other guys to drop it back to me. That was a pre-scout that I was going to go to the blocker side from our goalie coach Jeff Salajko. I hadn't been the best in shootouts in my career. I was actually going to plan to do another move and he kind of convinced me into doing it. It was a big goal for our team and it helps when Bernie was as good as he was tonight and in the shootout." - Larkin
Quotable II: "Larks was really good for us tonight. Obviously his end to end goal but he's playing good defensively and making simple plays down the stretch there." - Bertuzzi
Quotable III: "That's his move obviously, and he pulled that so quick. It's almost unstoppable for a goalie." - Bernier
Quotable IV: "You have to pick and choose your time and it's really hard. When you start winding up, people get in your way. The thing Dylan has learned over time is to not just rely on his legs and his speed and to buy space and use others and do those kind of things. That's one of those things where he happened to get the right opportunity, where the ice was available in front of him. He took it. You hate to be a guy with a bad gap against Dylan because he's coming fast and did a great job on the goal. But it's not something necessarily that I think you can do on a regular basis because people will just take angles on you and end the play." - Wings coach Jeff Blashill
Tweet from @DetroitRedWings: .@Dylanlarkin39 in the shootout! #LGRW pic.twitter.com/KVFy8PZlOD
2. Jonathan Bernier: Of Detroit's 12 wins this season, Bernier has earned 10 of those. There's no question he's had to work hard for them. That was the case again against the Senators Friday night. Rudolfs Balcers pounced on a giveaway at 3:57 of the first and Bernier stopped his shot from the left circle. The Senators sent 10 pucks Bernier's way in the first and Bernier saved them all. At 5:54 of the second, Brady Tkachuk's wraparound shot went off Patrik Nemeth's skate and into the net. Then the Senators scored on the power play at 10:42 of the second when Colin White tipped the puck past Bernier. Other than that, Bernier could not be beat. Tkachuk pushed hard to the net at 17:40 of the second and ended up on top of Bernier in the net but the puck did not get through. Bernier stopped Tyler Ennis and White during Ottawa's overtime power play. Then in the shootout, Bernier stopped Ennis, Anthony Duclair shot wide and then Bernier stoned Artem Anisimov for the win. Bernier is now 5-3-0 with a 2.09 goals-against average and .937 save percentage in his last nine outings.
Tweet from @DetroitRedWings: Hear from Bernier, Bert, Larkin and Coach Blashill following tonight's shootout W! #OTTvsDET #LGRW @CocaCola pic.twitter.com/2ThMuqPwwh
Quotable: "The legs were burning. I think obviously it's easier on 4-on-3. It just seems that they're missing one guy in the middle, so you kind of see them coming in and coming out, so I think it's easier to read. We did a good job. I think it's just confidence. I think the more I play, the more I feel confident and the better I see the puck and the play coming at me. You try to reproduce that in practice but it's pretty hard if you don't play for over 2-3 weeks. Obviously I feel good right now." - Bernier
Quotable II: "He's kept us in countless games, whether we lose or win. I know he's going to keep giving us those opportunities to win. If we can score some goals, we'll keep getting wins." - Bertuzzi
Quotable III: "It's put us where you see we're right in games. We've just built from him out, confidence in our team. He's done a great job. He's really been a calming factor back there. He's made the saves he's had to. He's been great for us. He's been everything, I think." - Larkin
Quotable IV: "The numbers say he is a better goalie when he plays more. That's just the history of it. I would probably say that's true of lots of guys. It's easier to get in a groove, it's easier to kind of keep rolling with it, so he's done a good job. He had a tough start to his time here in Detroit last season, the beginning of this season, neither one were probably what he wanted. The thing about him is he keeps a positive attitude, he keeps digging in and he works. I think that work's paying off." - Blashill
3. Tyler Bertuzzi/Filip Hronek: There is a reason that Bertuzzi will be the Red Wings representative at the All-Star Game in St. Louis later this month. He has been the most consistent - and consistently healthy, along with Larkin - offensive player for the team this season. At 14:55 of the first, Bertuzzi went to the right doorstep and was ready when Hronek sent a pass through traffic, scoring his team-leading 16th goal of the season. Bertuzzi has points in back-to-back games and has registered nine points (6-3-9) in his last 12. Robby Fabbri picked up the second assist. Bertuzzi, who assisted on Larkin's goal, was also part of a group that had a great chance to end the game in overtime at 1:55 but Hogberg made the saves on Bertuzzi and Filppula and Green hit the post. Bertuzzi was the first to go in the shootout but Hogberg was able to make the save. Bertuzzi finished with 24 shifts for 22:49, had two shots, one hit, one giveaway, one takeaway and was plus-1. An argument could also have been made that Hronek should represent the Wings at the All-Star Game as he has blossomed in his second season and first full season in the NHL. With his two assists, Hronek now has four multi-assist games, which leads the team. Hronek leads Detroit's defensemen in points with 25 (8-17-25) in 43 games. Last season Hronek had 23 points in 46 games. Hronek finished with 31 shifts for 25:03, had three shots, one hit, two giveaways, a double-minor penalty and was plus-1.
Tweet from @DetroitRedWings: What a look by Filip Hronek. #LGRW pic.twitter.com/5OszVVrWGS
Quotable: "I knew (Hronek) was looking at me the whole time. He just needed a better angle. That's when he walked it across and made the play. He's playing confidently and he's been unreal for us this year. He makes good plays, smart plays. Obviously from the two goals there, he's got his head up and making good plays." - Bertuzzi
Quotable II: "(Hronek's) been thrown in there and playing big minutes and a lot of responsibility and he's done a great job. I think every part of his game has matured. He's got a great shot, he's got a great first pass. When he's out there, he's a guy that'll get the puck on your stick. If you find him for his big one timer, it's always a dangerous play. He's been a big plus for us back there." - Larkin
Quotable III: "As long as the role mirrors later what he's going to do in his career and as long as his play mirrors it. By that I mean if you start playing outside of yourself because you got a bigger role than maybe you'd have if we were in a better spot in the standings, then that can be dangerous. That's not the case with Fil. I think he plays to his strengths, I think he knows what he is. He's done a really good job of trying to create offense without taking unneeded risk. He's certainly learning. Is he making mistakes? Yeah, he's making mistakes, he made mistakes tonight but he's learning as he goes and one thing he's done a good job of is being mentally tough. If you weren't mentally tough, first of all the non-mentally tough people normally don't make it to this level, but if you weren't really mentally tough right now, it could be some hard times. But he's really mentally tough." - Blashill
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The advent of the digital age has long been upon us. For most practices, this has created an interesting mix of skill sets within an office. Recent graduates have a great handle on the most current programs while those that have been in the industry for a little longer are finding themselves playing catch up. More often than not, a general amount of knowledge and appreciation is present, but the ability to produce the most striking of visuals is usually not there. Digital Drawing for Landscape Architecture is a comprehensive presentation of easy to follow tutorials and guides to help the digitally aware become the digitally adept.
Digital Drawing is the most recent offering by Bradley Cantrell and Wes Michaels. Bradley has been featured here on Land8 in 2013 as the recent winner of the Rome Prize Fellowship. The book is not best for those that are just starting out with the programs that the industry uses everyday. However, if you are versed enough recognize some of the tools that are in play, this book can take you to the next level. In a world where everyone is going digital, there is a subtle difference between a computer drawing and a finely tuned illustrative rendering. Understanding what it takes to elevate your techniques is crucial to having your work stand out amongst the others.
Digital Drawing does an excellent job of stressing the important things about this form of graphic making – flexibility is key. You can achieve the same result a multitude of ways, however, your ability to adjust a graphic quickly down the road will vastly improve the efficiency of your overall project.
Some highlights include Chapter 3 which explores the basic concepts of digital rendering. Though these are introductory – they still can be complicated for a beginner designer. The authors provide a great refresher for even the studio weary rendering specialist. If you are anything like me, then you picked up how to use Photoshop and Illustrator on your own through experimentation (read: frustration). Digital Drawing takes you back through the basics to remind you of the simple things that you may have never picked up. Do you remember the subtle difference between opacity and fill or perhaps the merits of different masks and when to use each?
Some of the most seemingly mundane tasks that are part of a graphic's construction are given entire chapters in Digital Drawing – and for good reason. Chapter 8 gives some quick but extremely useful directives for managing large files while Chapter 18 is 10+ pages on importing PDF line work. I believe that getting these mandatory techniques correct is very important because it sets the tone for the rest of your work on a given product. Better layer management, for instance, can be the difference between a quick, last minute edit and a sluggish, deadline missing revision.
Ultimately, Digital Drawing is an excellent resource for students, entry level designers, and those looking to refine their graphic skills for actual workplace applications. Even a person who believes themselves to be well versed in the ways of Photoshop, Illustrator, etc, such as myself, can find a ton of useful time saving tricks and refined techniques to make their workflow more efficient.
You can find Digital Drawing for Landscape Architecture – Second Edition on bookshelves now.
Bradley Cantrell is Principal of Visual Logic and Associate Professor of Architectural Technology at the Harvard Graduate School of Design. Bradley has been interviewed here on Land8 in 2013 as the recent winner of the Rome Prize Fellowship.
Benjamin Boyd is a licensed landscape architect working Baltimore, Maryland and is a proud graduate of the University of Florida School of Landscape Architecture. He also writes at Landscape Invocation.
Excellent review! Would you say these techniques apply to both small and large scale projects?
I just ordered this book! I am excited to use it in my current practice!
Ben – great review. I have the first edition of this book and it's fantastic! I've been telling my students to get it for the last few years so it's great to see a second revision with new content.
These techniques described in the book certainly apply to both large and small scale projects. However, the use of them depends on what makes sense for the particular project being developed. For example, depending of what you are trying to accomplish will depend on the software and techniques used. It is also important to maintain a workflow that can easily be editable through out the project.
Interesting LA publication…..but, it's just my opinion that James Richards' book "Freehand Drawing & Discovery" is a better tool for young Landscape Architects. It seems to me, that most young LAs have a fairly good grasp of "computer generated drawings"…..but, don't have a very good grasp of "freehand drawing" skills. Freehand drawings as illustrated in Mr. Richards' book are among the most outstanding I've seen in my 35+ LA career. His style & high quality would be an extremely beneficial skill to have…whether an LA is onboard a small or large LA firm…or even a freelance LA working on his/her own. This book is available on Amazon.com…I highly recommend it.


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As 40% of adults think Jesus is a myth, has Religious Education failed?
Gillan Scott
Richard Dawkins and the other prophets of atheism love to tell us that in the fabricated battle between religious belief and rationalism, there can be only one winner, and that their side is finally gaining the upper hand; the days of superstitious belief in sky pixies and the like are numbered – at least in the enlightened West. The tide is turning, and it is their hope that, in time, all religious belief, including Christianity, will be seen as little more than a dwindling remnant of the age of ignorance. This is the dawning of the Age of the Nones, where science and technology are the new gods to be worshipped and revered.
Certainly Christianity, though still the dominant faith in the United Kingdom, is in a bad way. Those who never progressed beyond the linear graphs of GCSE Maths will look at the decline in the number of professing Christians and calculate that, based on Census numbers going down from 72 per cent of the population in 2001 to 59 per cent in 2011, Christians will be about as common as chicken teeth by about 2060. If you happen to be a Methodist, things are even worse: your obituary is being readied for 2035.
But once you start digging deeper, the picture tells a set of more intricate stories. Even within the United Kingdom there are significant regional differences. A recent poll for the Theos think-tank found that Scotland is far more irreligious than the rest of the country, with 50 per cent of respondents having no religious faith compared to 35 per cent nationally. A quarter of the Welsh still attend a weekly service, almost double that of England and Scotland, and only 27 per cent of 18-24-year-olds actually describe themselves as Christian, compared to 79 per cent of the over 65s.
In that last and possibly most significant statistic, what we're really seeing is the obvious mass shift in identity from residual cultural Christianity to ill-informed agnosticism. For decades, people have been turning their backs on our churches and, as the generations have passed, knowledge of the Christian faith has dimmed as parents have failed to hand the light on to their children.
Yet, despite all the apparent gloom for the religious (and joy for the proactively anti-religious), there is another side to the coin. Life is unpredictable. Who, for example, is kicking themselves wishing they had put a couple of quid on Jeremy Corbyn back at the start of the Labour leadership contest, when he was a 200-1 longshot? Christianity has faced far greater threats in the past than its current wobble in Europe. The entire history of the olive branch which was grafted onto to the Judaic root has been one of continuous and miraculous survival. Put in the context of unending wars, persecution and systematic 'cleansing', the Faith has come through time and again. Only a brave or foolish commentator would predict the current decline as being terminal.
If you want to find signs of hope for the Christian faith, you need look no further than the new Perceptions of Jesus, Christians & Evangelism report, carried out for the Church of England, Evangelical Alliance and Hope. Based on extensive polling by ComRes, this focuses on practising Christians in England and there are plenty of juicy morsels which may come as a surprise. For example, nine per cent of the 3,000 respondents described themselves as practising Christians. Proportionately, as a percentage of their age groups, there are as many 18-34s as the over 65s, and approximately twice that of the 35-64 age bracket. This would suggest, contrary to popular belief, that the number of practising Christians, rather than declining, appears to have bottomed out and is now beginning to bounce back.
Almost one in five of employed practising Christians are working in education, and one in ten works in healthcare or education, which says something in itself of the effect that faith has in determining how Christians seek to live their lives. Four out of five working Christians have degrees, which is almost double the national average. Atheists might think their stance is by far the most credible and intellectually superior, but there are vast numbers of very well-educated people who have come to the opposite conclusion through both reasoning and experience. Christianity is anything but the preserve of naïve fools.
This last point might give the impression that our churches are full of white middle-class people, and yes, they are. But again, proportionately, you are much more likely to find a black adult who will profess the divinity of Jesus than you will of any other minority ethnic group.
43 per cent of all English adults believe in the resurrection of Jesus Christ from the dead, and one in five non-Christians, when talking about faith with a Christian, want to know more – even to the point of seeking an encounter with Jesus. This figure is higher among the 18-34s, and goes to show that there are millions of young adults in particular who want to know more about Jesus, despite their lack of knowledge. They just need to find someone to talk to who can enlighten them.
And there is a huge number of people who do need enlightening. Probably the most astonishing finding in the entire survey was that 22 per cent of respondents thought that Jesus was fictional, and almost as many again weren't sure if he ever actually existed. That's potentially 40 per cent of the population who know so little about the Christian faith that they are not remotely aware of the overwhelming historical evidence that Jesus was a real man.
It is quite staggering that our education system is producing so many adults who are so incredibly ill-informed about the basics of Christianity. The fact that the majority of children have had minimal contact with a church is not an excuse. We live in a time when religion is in the news almost every day. It impacts each of us at some level through global tensions and conflicts, as well as through the communities we live in and relationships we hold. The ignorance is only set to increase over the years ahead, and religious illiteracy leads inevitably to misunderstanding, distrust and hostility.
Anyone who is familiar with the way Religious Education is taught in schools will know how detached it is from the realities of everyday faith, if not life itself. It is not primarily the fault of the teachers, but more often the gross inadequacies of the syllabus they are required to teach, not to mention its position in the school curriculum. It is mandatory, but sidelined. It is central, but often entrusted to part-time geography teachers or anyone who happen to be Christian/Muslim/vaguely-interested-in-religion. The GCSE exams are woefully inadequate. Investment in the training of qualified teachers has been more than decimated in favour of more 'rigorous' subjects. It focuses too much on ritual, stories, festivals and generalised views, leaving students unable to grasp the theological and factual foundations to help them make sense of what they see going on in the world around them.
This is not just my opinion. Various academics and educationalists agree this is the case. So, too, does Ofsted, which accused more than half of England's schools of failing to provide adequate Religious Education in 2013.
I asked the Rev'd Nigel Genders about this. He's the Church of England's Chief Education Officer, and he said:
More than one million children – of all faiths are none – are educated in our church schools, and through RE, collective worship and the Christian ethos of the school they will all hear about Jesus and the significance of his life, death and resurrection and how it can impact them today. We are committed to excellent RE and are producing a new resource to transform the teaching about Christianity, which is currently being piloted in Church schools and community schools as well.
Well, that's potentially good news. That's a big chunk of our school population who will leave school knowing that Jesus isn't a mythical being. We've just got to persuade the government and advise headteachers and governing bodies to do something about the remaining seven million who aren't going to be so fortunate.
More Under: Agnosticism, Atheism, Census, Christian persecution, Christianity, Church attendance, Church decline, Church growth, Church of England schools, ComRes, Education, Ethnic Minorities, Evangelical Alliance, Evangelism, God, Hope, Jesus, Methodism, Mission, Nigel Genders, Ofsted, Opinion polls, Perceptions of Jesus, Religious Education, Religious illiteracy, Richard Dawkins, Schools, Secularism, Teaching, Theos
'Prevent Duty' teacher: "If you say homosexuality is wrong, you might be breaking the law"
Warwick University Student Union incites hatred by banning criticism of Islam

redpajama_set_name: RedPajamaCommonCrawl


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Have you been depriving yourself of free therapy? If you avoid washing the dishes you have—at least according to a new study from Florida State University and published in the journal Mindfulness. They found that study participants experienced a 27% reduction in nervousness and a 25% increase in feelings of inspiration by washing dishes. There is one important thing to consider: the subjects were instructed to focus on the experience of washing dishes. They focused on the feel of the warm water and the smell of the dish soap. In short, they were mindful and present in the moment and that produced very positive, therapeutic benefits.
Disciple: I have just entered the monastery. Please teach me the first Zen lesson.
Master: Have you finished eating your rice porridge?
Master: Then you had better wash your bowl.
While this study (and the ancient story) was, on the surface, about washing dishes, it was really about how to wake up and live.
Do You Tie Your Shoes In Your Sleep?
When you were a child everything was new to you. You were awake and aware of the smallest details around you because you had never encountered many of them before. As you grew, you started creating automatic response to your surrounding world.
For instance, when you learned to tie your shoelaces, you were very attentive to every detail of the process. Now you do it "mindlessly" because it is an automatic, subconscious process. You've stopped noticing the texture and feel of the laces; you've stopped marveling at how a single strand can bind your shoes to your feet. What's really happened? YOU HAVE FALLEN ASLEEP. Or, more aptly, you are dreaming. You are not doing what you're doing—that's happening automatically and unconsciously—you are dreaming about something; whatever it is you're thinking about beyond the act of tying your shoes. This automatic functioning is often at the root of many problems you encounter. In fact, much of the work we do in N.L.P. and hypnosis is about altering the automated responses one has to situations that arise in life.
There is nothing complex about washing dishes and as you do this chore it's very easy to think about your bills, a fight with your co-worker, etc., etc. Generally, however, your awareness is focused on things that you CAN'T do anything about because you're busy washing the dishes.
You are living in the fantasy of the future (and whatever you think about the "future," it is always a fantasy because it doesn't exist. In fact it never will exist… but that's a different topic.) Maybe, as you wash the dishes, you are ruminating on some wrong that was done to you. Again, you are living in a dream, a fantasy that is happening right now in your consciousness. What are you NOT doing? You are not washing the dishes with awareness. And if you were to move your attention to the feel of the soapy water or the texture of the sponge, your mind couldn't create all of those bad feelings by thinking about your bills or your disagreements with others. Subsequently, you feel more peace because your are present with the dishes.
This isn't really about washing dishes at all. It's about being where you are and doing what you're doing. If you're feeling stressed out and nervous, I'll bet that you are busy fighting some battle in your mind; or worrying about some future event like funding your retirement; or just going over your endless to-do list.
Ready to stop dreaming—or nightmare-ing? If you are reading this at your computer, take a minute to put your hand on your mouse and just try to determine what temperature it is. Focus on its temperature for a while. Now, start feeling the texture of the mouse. Really observe it. Notice that, while your mind will try to run off and do what it always does—dream—you can just bring it back to the subject at hand. Before long you might notice that you are feeling calmer. You are forcing yourself to experience "this" moment; not some fantastical future moment. There is great peace in this moment. You might even discover that if you can just be in this moment, you can find a kind of bliss. Who knows, do it right and like the neophyte monk in the Zen koan above, you might just find enlightenment.
Here's an exercise I give my clients at The Meridian Center who want to start being more present in the moment. I ask them to close their eyes, lean their heads back and slowly breath in through their noses for five seconds. Then hold that breath for five seconds. Then breathe it out for five seconds. Just count "one Mississippi, two Mississippi, etc." Try to stay focused on the breath. You'll probably notice that after about four or five breaths you're feeling calmer and more peaceful. Again, this is akin to washing the dishes "mindfully" because you are just doing what you're doing and not doing what you're not doing.
The world is full of distractions that can disturb your peace. If you take a moment and acknowledge that you might just be running off into a waking dream and losing touch with what is happening right now, you can start to live mindfully and enjoy the profound peace that each moment holds for you.
You can read a synopsis of the research study here.


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The effect of nicotine on glycogen synthesis
K. Rosen, S. Fontaine, H. Chowaniec, L. Burdjck, Cynthia J Hartzell, H. Gunderson
The purpose of this study was to determine the effect of nicotine on glycogen synthesis. Following a 24 hour fast, female Sprague-Dawley rats were infused for 2 hours at 9-5 ul/rnin with 25% [1-13C] glucose. In addition, the infusate contained 1.1 rnM nicotine bitartrate for the nicotine treated animals(N) and no nicotine for the control group(C). After the infusion, the animal was anes(hetized, liver tissue was removed, freeze clamped and stored at -85C. NMR spectra indicate the glycogen was synthesized using a greater amount of direct pathway in N compared to C (52% vs 29%, P-0.012). Liver glycogen concentration was 23.2 mg/g for C and 10.8 mg/g for N (P<0.001). The effect of nicotine was to increase the use of the direct pathway, but decrease the amount of net glycogen synthesis. Results indicate that the natural pathway of glucose is modified by nicotine in such a way as to more directly convert it to glycogen before allowing it to be used by peripheral tissues.
FASEB Journal
Liver Glycogen
Sprague Dawley Rats
Rosen, K., Fontaine, S., Chowaniec, H., Burdjck, L., Hartzell, C. J., & Gunderson, H. (1998). The effect of nicotine on glycogen synthesis. FASEB Journal, 12(8).
The effect of nicotine on glycogen synthesis. / Rosen, K.; Fontaine, S.; Chowaniec, H.; Burdjck, L.; Hartzell, Cynthia J; Gunderson, H.
In: FASEB Journal, Vol. 12, No. 8, 1998.
Rosen, K, Fontaine, S, Chowaniec, H, Burdjck, L, Hartzell, CJ & Gunderson, H 1998, 'The effect of nicotine on glycogen synthesis', FASEB Journal, vol. 12, no. 8.
Rosen K, Fontaine S, Chowaniec H, Burdjck L, Hartzell CJ, Gunderson H. The effect of nicotine on glycogen synthesis. FASEB Journal. 1998;12(8).
Rosen, K. ; Fontaine, S. ; Chowaniec, H. ; Burdjck, L. ; Hartzell, Cynthia J ; Gunderson, H. / The effect of nicotine on glycogen synthesis. In: FASEB Journal. 1998 ; Vol. 12, No. 8.
@article{6e1667c4ac934bc081e0b5c53c95f4e1,
title = "The effect of nicotine on glycogen synthesis",
abstract = "The purpose of this study was to determine the effect of nicotine on glycogen synthesis. Following a 24 hour fast, female Sprague-Dawley rats were infused for 2 hours at 9-5 ul/rnin with 25{\%} [1-13C] glucose. In addition, the infusate contained 1.1 rnM nicotine bitartrate for the nicotine treated animals(N) and no nicotine for the control group(C). After the infusion, the animal was anes(hetized, liver tissue was removed, freeze clamped and stored at -85C. NMR spectra indicate the glycogen was synthesized using a greater amount of direct pathway in N compared to C (52{\%} vs 29{\%}, P-0.012). Liver glycogen concentration was 23.2 mg/g for C and 10.8 mg/g for N (P<0.001). The effect of nicotine was to increase the use of the direct pathway, but decrease the amount of net glycogen synthesis. Results indicate that the natural pathway of glucose is modified by nicotine in such a way as to more directly convert it to glycogen before allowing it to be used by peripheral tissues.",
author = "K. Rosen and S. Fontaine and H. Chowaniec and L. Burdjck and Hartzell, {Cynthia J} and H. Gunderson",
journal = "FASEB Journal",
publisher = "FASEB",
T1 - The effect of nicotine on glycogen synthesis
AU - Rosen, K.
AU - Fontaine, S.
AU - Chowaniec, H.
AU - Burdjck, L.
AU - Hartzell, Cynthia J
AU - Gunderson, H.
N2 - The purpose of this study was to determine the effect of nicotine on glycogen synthesis. Following a 24 hour fast, female Sprague-Dawley rats were infused for 2 hours at 9-5 ul/rnin with 25% [1-13C] glucose. In addition, the infusate contained 1.1 rnM nicotine bitartrate for the nicotine treated animals(N) and no nicotine for the control group(C). After the infusion, the animal was anes(hetized, liver tissue was removed, freeze clamped and stored at -85C. NMR spectra indicate the glycogen was synthesized using a greater amount of direct pathway in N compared to C (52% vs 29%, P-0.012). Liver glycogen concentration was 23.2 mg/g for C and 10.8 mg/g for N (P<0.001). The effect of nicotine was to increase the use of the direct pathway, but decrease the amount of net glycogen synthesis. Results indicate that the natural pathway of glucose is modified by nicotine in such a way as to more directly convert it to glycogen before allowing it to be used by peripheral tissues.
AB - The purpose of this study was to determine the effect of nicotine on glycogen synthesis. Following a 24 hour fast, female Sprague-Dawley rats were infused for 2 hours at 9-5 ul/rnin with 25% [1-13C] glucose. In addition, the infusate contained 1.1 rnM nicotine bitartrate for the nicotine treated animals(N) and no nicotine for the control group(C). After the infusion, the animal was anes(hetized, liver tissue was removed, freeze clamped and stored at -85C. NMR spectra indicate the glycogen was synthesized using a greater amount of direct pathway in N compared to C (52% vs 29%, P-0.012). Liver glycogen concentration was 23.2 mg/g for C and 10.8 mg/g for N (P<0.001). The effect of nicotine was to increase the use of the direct pathway, but decrease the amount of net glycogen synthesis. Results indicate that the natural pathway of glucose is modified by nicotine in such a way as to more directly convert it to glycogen before allowing it to be used by peripheral tissues.
JO - FASEB Journal
JF - FASEB Journal


text:
Q: What are my options/resources for playing audio in C#? I'm aware of how to play sound in C#,
for example:
System.Media.SoundPlayer player = new System.Media.SoundPlayer(@"c:\local_file.wav");
player.Play();

However, I wanted to know if C# contained some sort of sound library, like files that are built in to the system that I can use, or something that generates sound (e.g. text to speech.) Basically, I just want to know what my options are for playing sound in my program, and/or whether I have any "resources" other than my own downloaded files.

A: C# is a progamming language.  It runs on many different platforms, each of which support many different libraries.
The SoundPlayer class in the .Net System.media namespace is one very good choice for Windows.  Similarly NAudio or IRKlang might be good choices for doing audio in C# on Linux.
There isn't necessarily any "single best, one size fits all" choice.  You have many different options, depending on your platform, your requirements, and your personal preferences.

redpajama_set_name: RedPajamaStackExchange


Hey guys! I'm organising my first HUGE giveaway for my beauty blog(yeah, my first huge one) to thank you guys for the consistent suppost ever since I started Dreams of a Beauty-a-holic few months ago. And it is REALLLY amazing to see 15 followers for my new beauty blog, a huge encouragement for me to do more beauty reviews and that means...MORE GIVEAWAYS!
I hope that there would be more beauty junkies(I'm one of them) reading my blog and enjoying my reviews and event posts.
The mystery gift might be something from MAC or something on the shelves of Sephora.
I assure you that there will be definitely more giveaways coming up in the upcoming days and months. Here's now to enter the giveaway; you can enter as many times as you wish(max 2 per day) and between 7 July 2011 to 7 August 2011.
This entitles you to one entry for the giveaway.
2. By sharing this post on your FaceBook page. This entitles you to three entries for the giveaway.
3. Do a short blog post about this giveaway. Each blog post entitles you to five entries for the giveaway.
4. You must be able to collect the prize personally(from myself) at Bugis MRT during weekdays.
5. This giveaway is only valid in Singapore and the deadline would be 7 August 2011, 2359.
After sharing the link, please do a printscreen to me via email at cheryl_forgottened@ymail.com.
If you have done up a short blog post, kindly send me your blog link. Do include your Google Friend Connect username in the email!
Wishing you guys the best of luck and enjoy my upcoming reviews, including Maybelline HyperSharp Eyeliner and Kiehl's Amino Acid Shampoo!


text:
Artemether-lumefantrine versus artemisinin-naphthoquine in Papua New Guinean children with uncomplicated malaria: a six months post-treatment follow-up study
Moses Laman1,2,
John M Benjamin2,
Brioni R Moore1,2,
Mary Salib2,
Somoyang Tawat2,
Wendy A Davis1,
Peter M Siba2,
Leanne J Robinson2,3,4 &
Timothy ME Davis1
In a recent trial of artemisinin-naphthoquine (artemisinin-NQ) and artemether-lumefantrine (AM-LM) therapy in young children from Papua New Guinea (PNG), there were no treatment failures in artemisinin-NQ-treated children with Plasmodium falciparum or Plasmodium vivax compared with 2.2% and 30.0%, respectively, in AM-LM-treated children during 42 days of follow-up. To determine whether, consistent with the long elimination half-life of NQ, this difference in efficacy would be more durable, clinical episodes of malaria were assessed in a subset of trial patients followed for six months post-treatment.
For children completing trial procedures and who were assessable at six months, all within-trial and subsequent clinical malaria episodes were ascertained, the latter by clinic attendances and/or review of hand-held health records. Presentations with non-malarial illness were also recorded. Differences between allocated treatments for pre-specified endpoints were determined using Kaplan-Meier survival analysis.
Of 247 children who were followed to Day 42, 176 (71.3%) were included in the present sub-study, 87 allocated to AM-LM and 89 to artemisinin-NQ. Twenty children in the AM-LM group (32.8%) had a first episode of clinical malaria within six months compared with 10 (16.4%) in the artemisinin-NQ group (P = 0.033, log rank test). The median (interquartile range) time to first episode of clinical malaria was 64 (50–146) vs 116 (77–130) days, respectively (P = 0.20). There were no between-group differences in the incidence of first presentation with non-malarial illness (P = 0.31).
The greater effectiveness of artemisinin-NQ over conventional AM-LM extends to at least six months post-treatment for clinical malaria but not non-malarial illness.
Australian New Zealand Clinical Trials Registry ACTRN12610000913077.
Artemisinin-based combination therapy (ACT) has emerged as first-line treatment for uncomplicated malaria in most malaria-endemic countries because of the high cure rate, relative safety, transmission-blocking potential, and ability to delay the development of parasite drug resistance [1]. Its place in management of malaria has been cemented through randomized clinical trials, but there is uncertainty regarding the optimal duration of follow-up for determining efficacy. The World Health Organization (WHO) currently recommends Day 42 as the maximum follow-up time-point for trials involving longer half-life ACT partner drugs [2,3], but there is theoretical evidence that at least 56 days of follow-up should be considered for trials of falciparum malaria involving ACT partner drugs with elimination half-lives that are longer than one week [4]. In the case of vivax malaria, and in trials of falciparum malaria in areas where Plasmodium vivax is transmitted, late post-treatment recurrences can result from relapses from dormant liver stages. Durations of follow-up of up to 63 days have been employed in this situation [5]. However, a longer duration of follow-up increases the complexity and cost of clinical trials, while attrition rates of patients, and also trained research staff [6], are likely to increase.
In a recent comparative efficacy and safety trial of three daily doses of artemisinin-naphthoquine (artemisinin-NQ) and conventional artemether-lumefantrine (AM-LM) therapy in young children from north coastal Papua New Guinea (PNG) with uncomplicated falciparum and/or vivax malaria [7], there were no reappearances of asexual forms of either Plasmodium falciparum or P. vivax during the WHO-recommended 42 days of follow-up in any child in the artemisinin-NQ group. The greater number of recurrent infections after AM-LM may have reflected the shorter elimination half-life of LM compared with NQ (4–5 days [8] vs 21–25 days [9]). To assess this possibility and in light of the possible need for prolonged follow-up in such ACT trials [4], a subset of trial participants were followed for a period of six months post-treatment. It was hypothesized that, in coastal PNG where malaria transmission is at least moderate and recurrent malaria in children aged ≤5 years is common [10], the incidence of clinical episodes of malaria during prolonged follow-up would reflect the elimination half-life of the non-artemisinin partner drug.
Study setting, design and approvals
The present study was conducted at Mugil and Alexishafen Health Centres in Madang Province on the north coast of mainland PNG. The malaria entomological inoculation rate (EIR) in this setting has been estimated at 37 for P. falciparum and 24 for P. vivax [10]. Although there has been a significant decline in falciparum malaria after the introduction of malaria control programs, the incidence of vivax malaria has remained unchanged over the last three decades [10,11].
The parent trial was a randomized, comparative, efficacy trial of AM-LM and artemisinin-NQ (Australian New Zealand Clinical Trials Registry ACTRN12610000913077) [7]. In the present sub-study, all children completing trial procedures were followed subsequently for two primary outcomes; i) the cumulative incidence of clinical episodes of malaria within-trial (up to Day 42) and post-trial (up to 6 months after treatment), and ii) the median time to the clinical episodes of malaria within six months of allocated treatment. Secondary outcomes were; i) the incidence of non-malarial illness between treatment groups within six months of allocated treatment, and ii) the median time to episodes of a non-malarial illness within six months of allocated treatment. Both the parent trial and present sub-study were approved by the PNG Institute of Medical Research Review Board, the PNG Medical Research Advisory Committee (MRAC 10.39) and the University of Western Australia Human Research Ethics Committee. Written informed consent was obtained from parents/guardians of all children before participation.
Children aged between 6 months and 5 years with uncomplicated malaria were recruited to the parent trial between March 2011 and April 2013 provided that they had; i) an axillary temperature >37.5°C or fever during the previous 24 hours, ii) P. falciparum (>1,000 asexual parasites/μL whole blood) and/or P. vivax (>250/μL) on a peripheral blood smear, iii) not used study drugs in the past 14 days, and iv) no clinical or laboratory evidence of severe malaria or other infection [7].
Within-trial clinical and laboratory procedures
Within-trial clinical and laboratory procedures have been described previously [7]. Briefly, children were randomly assigned by use of a computer-generated random numbers in blocks of 24 by site to receive AM-LM (1.7:10 mg/kg; Novartis Pharma, Basel, Switzerland) twice-daily for three days with milk as per manufacturer's recommendation or artemisinin-NQ (20:8 mg/kg; Kunming Pharmaceutical Corporation, Yunnan, China) daily with water for three days. Treatment allocation was concealed from investigators by use of an opaque, sealed, and sequentially numbered envelope that was opened only after the patient was enrolled. Serial clinical and laboratory assessments including axillary temperature and malaria microscopy were performed on Days 1, 2, 3, 7, 14, 28 and 42.
Early treatment failure was defined as the development of signs of severity or an inadequate parasitological response by Day 3 [12]. Any child who developed parasitaemia between Days 4 and 42 was considered to have late parasitological failure or, if febrile (axillary temperature >37.3°C), late clinical failure. Children without any of the above WHO definitions of treatment failure were considered to have an adequate clinical and parasitological response (ACPR). Plasmodium falciparum re-infection and recrudescence were distinguished using polymerase chain reaction genotyping of merozoite surface proteins (MSP1 and MSP2) based on paired samples collected on Day 0 and at reappearance during the active follow-up period [13,14]. Plasmodium vivax recrudescence was determined based on genotyping of MSP1F3 and Microsatellite 16 [15]. Malaria blood smears were examined independently by two skilled microscopists [7]. The WHO-recommended method of parasite density calculation based on the number/200-500 leucocytes and an assumed leucocyte count of 8,000/μL [16] was used and has been validated for the study setting [17].
Post-trial follow-up
During the post-trial follow-up period, parents/guardians were asked to bring their children back to the Mugil or Alexishafen Health Centres if the child became unwell or developed fever within the six months after allocated treatment. In all these cases, field microscopy for malaria parasites or a malaria rapid diagnostic test (RDT; CareStart® HRP-2/pLDH (Pf/pan) Combo Test, AccessBio, Somerset, NJ, USA) was performed. All malarial and non-malarial illnesses during the post-trial follow-up period were treated according to PNG national guidelines [18].
Initially, the parents/guardians of the children who did not re-attend with an illness within six months were visited in their villages at the end of this period and their child's health record books were examined to document malarial or non-malarial illnesses that may have been missed due to attendance at another health care facility. However, this practice was discontinued because of logistic difficulties and the fact that an additional primary endpoint was identified in less than <1% of these cases. However, those children still within the six-month follow-up period when the Mugil and Alexishafen Health Centres closed (on Day 42 of the last randomized patient) were excluded from the present study because all their post-trial outcomes could not be ascertained.
Data are presented as mean ± SD or median [inter-quartile range]. Two-sample comparisons for normally-distributed variables were by Student's t-test, for non-normally distributed variables by Mann Whitney U-test, and for proportions by Fisher's exact test. Differences between allocated treatments for pre-specified primary and secondary endpoints were determined using Kaplan-Meier survival analysis and the log rank test. All P-values are two-tailed and unadjusted for multiple comparisons.
Of the 267 children randomized in the parent trial, 247 (92.5%) were followed to Day 42. Of this latter number, 176 (71.3%) were included in the six month analysis, comprising 87 allocated to AM-LM and 89 to artemisinin-NQ (see Figure 1). The 71 children who were excluded were those who had not attended the Mugil and Alexishafen Health Centres post-trial and were still within the six month follow-up period when the two clinics closed at the end of the parent trial. There were no deaths or non-infection-related clinic attendances amongst the 176 included children, and no differences in baseline characteristics by allocated treatment except that more artemisinin-NQ-treated children presented with vivax malaria (see Table 1).
Profile of patients followed from randomization to the end of the six-month follow-up period.
Table 1 Baseline characteristics of children who completed six months of follow-up classified by allocated treatment
Episodes of clinical malaria
In the AM-LM group, 20 (32.8%) children had a first episode of clinical malaria (due to either P. falciparum or P. vivax) within six months of treatment (see Table 2). This included 4 who developed clinical malaria within-trial [7], 12 who developed clinical malaria post-trial, and 4 who were recorded as late parasitological failure during the trial without being treated and who subsequently developed clinical malaria during the post-trial period on Days 56, 62, 140 and 154, respectively. Of these 20 patients, 18 (90%) had falciparum malaria and two (10%) had vivax malaria at enrolment. In the artemisinin-NQ group, there was no late parasitological or clinical failure during the 42 days within-trial. However, 10 children developed clinical malaria between Days 52 and 152 (16.4%, P = 0.046 vs AM-LM; see Table 2). Of these 10 patients, five (50%) had falciparum malaria, four (40%) had vivax malaria and 1 (10%) had a mixed species infection at baseline. Kaplan-Meier analysis showed that the incidence of a first episode of clinical malaria during six months of follow-up was higher in the AM-LM group (P = 0.033 by log rank test; see Figure 2). The median time to the first episode of clinical malaria was 64 days in the AM-LM and 116 days in the artemisinin-NQ group (P = 0.20; see Table 2).
Table 2 Endpoints by allocated treatment for the 176 children with data for six months after trial entry
Kaplan-Meier survival analysis showing the proportions of children treated with artemether-lumefantrine (solid line) and artemisinin-naphthoquine (dashed line) remaining free of clinical malaria during six months after allocated treatment. The P-value for the log rank test is shown.
If only those children who had an ACPR at Day 42 in the parent trial were considered, 12 of the 37 in the AM-LM group (32.4%) and 10 of 89 in the artemisinin-NQ group (11.2%) had an episode of clinical malaria between six weeks and six months after treatment (P = 0.008).
From the available data relating to species of Plasmodium detected in the 30 patients who developed clinical malaria during follow-up, these children were classified as belonging to one of five sub-groups; i) definite P. falciparum (slide or RDT positive for this species), ii) definite P. vivax (slide or RDT positive for this species), iii) definite mixed P. falciparum/P.vivax (slide positive for these species), iv) P. falciparum with or without P. vivax (an RDT reported as 'mixed' since the presence of both HRP-2 and pan-pLDH lines indicates an infection with P. falciparum, or a mixed infection including P. falciparum), and v) unknown (RDT recorded as positive without further details in the health record book). There was no difference between the proportions of children in each category by allocated treatment (see Table 3; P = 0.12 by Fisher's exact test). In 19 out of the 30 cases (63.3%), there was definite slide or RDT evidence of P. falciparum infection.
Table 3 Plasmodium species categorization of cases of clinical malaria during follow-up, based on microscopy and/or rapid diagnostic testing, by allocated treatment
Episodes of non-malarial illness
Twenty-one (24.1%) and 16 (18.0%) of children in the AM-LM and artemisinin-NQ groups, respectively, had a first episode of non-malarial illness during the six-month follow-up period (P = 0.36; see Table 1). Kaplan-Meier analysis showed that the incidence of non-malarial illness was not significantly different between groups (P = 0.31 by log rank test). There was also no significant between-group difference in the time to the first episode of a non-malarial illness (medians 123 and 107 days, respectively; see Table 2). Most had respiratory infections (32.4%) or skin infections (24.3%). There were no differences in the percentages of children who had more than one non-malarial illness during follow-up (63.2% in AM-LM group vs 55.1% in the artemisinin-NQ group; P = 0.27).
The present study shows that the relative clinical benefits of artemisinin-NQ over conventional AM-LM therapy extend well beyond the 42 days of the parent trial. Artemisinin-NQ was associated with approximately half the risk of a first episode of clinical malaria during follow-up over six months. The parallel nature of the Kaplan-Meier curves and the between-treatment difference in median time to first malarial episode suggest that the long half-life of the NQ component of artemisinin-NQ delays malaria post-treatment susceptibility relative to AM-LM by 7–8 weeks. This is equivalent to 2–3 NQ elimination half-lives in PNG children [9]. In the patients allocated to AM-LM, the relatively rapid elimination of LM and its active metabolite desbutyl-LM [8,19] is unlikely to afford protection from reappearance of malaria or a new malarial infection beyond the 42 days of the parent trial. Despite the higher haemoglobin concentrations in the artemisinin-NQ group at the end of the parent trial [7] and the recognized association between anaemia and bacterial infection in young children in the tropics [20-22], there was no protective effect of artemisinin-NQ treatment on the risk of non-malarial (mainly bacterial) infections in patients in this study.
There is evidence that local malaria transmission intensity may play a role in the efficacy of longer-acting partner drugs [23,24]. In one trial in which patients were followed up beyond Day 42 in an area of intense malaria transmission in Uganda (P. falciparum EIR 562 [25]), there was no difference in malaria reinfection rates in children receiving AM-LM or dihydroartemisinin-piperaquine at Day 63 despite the longer elimination half-life of piperaquine [23]. In the more moderate transmission setting of the present study (P. falciparum EIR 37 [10]), the post-treatment prophylactic effect of NQ was evident at Day 63 and beyond. However, the ability of NQ to suppress relapses of P. vivax may have been a contributor to the between-group differences in late clinical malaria in the patients [7], a consideration not relevant to sub-Saharan Africa. Unfortunately, the exact relative contribution of P. vivax infections could not be ascertained accurately because in 70% of cases the RDT was reported as 'mixed' or simply positive.
Antimalarial drugs such as NQ with long elimination half-lives are more likely to promote the development of parasite resistance as a result of prolonged sub-therapeutic plasma concentrations [26,27]. In the case of PNG, chloroquine has provided a salutary example in that sustained and widespread use has resulted in clinically significant parasite resistance and the need for alternative treatments [28]. However, the 'mandatory' combination of newer long-acting drugs such as NQ with an artemisinin derivative [1,3] is likely to be protective, and even triple therapy regimens are being considered to limit the possibility of parasite resistance [29]. The widespread deployment of artemisinin-NQ in countries such as PNG may be justifiable based on prolonged efficacy/effectiveness such as demonstrated in the parent trial [7] and present data, but in vivo, in vitro and/or genetic monitoring of parasite resistance should be an integral part of this process.
The present study had limitations. Neither accurate differentiation between Plasmodium species nor genotyping to differentiate recrudescences from reinfections was performed, but the primary endpoint (clinical malaria) was a pragmatic one designed to allow the long-term real-world effectiveness of the two treatment regimens to be assessed. For logistic and financial reasons, not all participants in the parent trial at each site were followed for the full six months, but most children were included and the two treatment groups were similar in number and baseline characteristics. Indeed, the significantly greater number of vivax cases in the artemisinin-NQ group and the potentially high rate of associated late relapses may have led to bias against this ACT, but it nonetheless proved more effective than AM-LM.
The present study is one of the few published in the literature that have employed long-term follow-up of patients with malaria treated with artemisinin combination therapy. The data suggest strongly that the long terminal elimination half-life of three daily doses of NQ confers benefit of artemisinin-NQ over AM-LM to at least six months post-treatment. This observation should favourably influence cost-effectiveness analyses. In addition, the present long-term follow-up data also add to the reassuring results of detailed safety monitoring over 42 days in the parent trial [7], in that there were no unsuspected late sequelae after three daily doses of artemisinin-NQ rather than the single dose recommended by the manufacturer.
ACPR:
Adequate clinical and parasitological response
Artemisinin combination therapy
Artemether
EIR:
Entomological inoculation rate
LM:
Lumefantrine
MSP:
Merozoite surface protein
NQ:
Naphthoquine
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Al-Yaman F, Genton B, Mokela D, Narara A, Raiko A, Alpers MP. Resistance of Plasmodium falciparum malaria to amodiaquine, chloroquine and quinine in the Madang Province of Papua New Guinea, 1990–1993. P N G Med J. 1996;39:16–22.
Shanks GD, Edstein MD, Jacobus D. Evolution from double to triple-antimalarial drug combinations. Trans R Soc Trop Med Hyg. 2014;109:182–8.
We thank the patients and their families for participating in this study. We also thank all the study nurses, health centre staff at Mugil and Alexishafen clinics, and the PNG Institute of Medical Research staff at the Yagaum campus for logistic and administrative support.
This study was funded by a National Health and Medical Research Council (NHMRC) of Australia grant (#634343). ML was supported by an Australian Award PhD Scholarship, BRM by a NHMRC Early Career Fellowship (#1036951), LJR by a NHMRC Early Career Fellowship (#1016443), and TMED by an NHMRC Practitioner Fellowship (#572561).
School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, PO Box 480, Fremantle, 6959, WA, Australia
Moses Laman, Brioni R Moore, Wendy A Davis & Timothy ME Davis
Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea
Moses Laman, John M Benjamin, Brioni R Moore, Mary Salib, Somoyang Tawat, Peter M Siba & Leanne J Robinson
Infection and Immunity Division, Walter and Eliza Hall Institute, Parkville, VIC, Australia
Leanne J Robinson
Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia
Moses Laman
John M Benjamin
Brioni R Moore
Mary Salib
Somoyang Tawat
Wendy A Davis
Peter M Siba
Timothy ME Davis
Correspondence to Timothy ME Davis.
All authors contributed to the design of this study, collection of data, analysis of data and/or the interpretation of the results, and/or to the writing of the manuscript. All authors edited and approved the final version of the manuscript.
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/.
The Creative Commons Public Domain Dedication waiver (https://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Laman, M., Benjamin, J.M., Moore, B.R. et al. Artemether-lumefantrine versus artemisinin-naphthoquine in Papua New Guinean children with uncomplicated malaria: a six months post-treatment follow-up study. Malar J 14, 121 (2015). https://doi.org/10.1186/s12936-015-0624-4
Plasmodium vivax


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Q: Case statement with braces Why does a case statement allow declarations within braces but not without them?
For example, the following is  not OK
switch (op->name) {
    case 0:
        int a = 2;
    case 1:
        int b = 3;
}

But the following is OK:
switch (op->name) {
    case 0:
       {int a = 2;}
    case 1:
       {int b = 3;}
}

What does the braces resolve that, without them, a declaration would be ambiguous to the compiler? To me (a beginner in C) it seems like each case statement should have an implied braces until the next case/default/end-of-switch, but that is obviously wrong!

A:
Why does a case statement allow declarations within braces but not without them?

My compiler emits this error message:

error: a label can only be part of a statement and a declaration is not a statement

That's pretty clear I think.  Labels, including case labels, are not considered independent statements or declarations, but rather components of statements.  When control branches to a label, whether via a switch or a goto, it is the statement of which the label is a part to which the program jumps.  Not to the label itself, which typically has no runtime representation.
Declarations such as int a; are not statements, and labels cannot be part of declarations.  On the other hand, blocks such as { int a; } are statements, and as statements, they can have labels.
There's no fundamental underlying constraint here.  It would have been possible for C syntax to have been defined differently, so that both of your examples were valid.  It just wasn't.

A: The reason this is invalid:
switch (op->name) {
    case 0:
        int a = 2;
    case 1:
        int b = 3;
}

Is because you have a label (in this case a case label) in front of a declaration.  A label may only appear before a statement.
Using braces works because they are used to denote a compound statement, which is a particular type of statement, and a statement can immediately precede a label.
Formally, a label is part of a labeled statement.  This is spelled out in section 6.8.1 of the C standard:

labeled-statement:
  identifier : statement
  case constant-expression : statement
  default : statement

A: Try this, and you'll get no error:
switch (op->name) {
    case 0:; /* <--- that ; is essential, see below */
        int a = 2;
    case 1:; /* <--- the same here. */
        int b = 3;
}

The problem is that the case statement is a special case of statement, but a declaration is not a valid substitute of a statement, so a declaration is not allowed immediately after a case label.  But you can always end the case_statement with a semicolon (issuing a null statement), and put your declaration right after it.


Having quality anti-malware (often called antivirus) software on all of your computers is vital. So vital, it is mandatory for all healthcare, banking, government, military, and any other IT systems that must meet compliance requirements.
The anti-malware that is built into both Windows and macOS do a fair job of protecting your computer, but it is simply not good enough!
Most computer users operate without 3rd-party anti-malware. Which goes a long way to explaining why there are hundreds of millions of malware infections, over $24 Billion in credit card fraud, and an epidemic of identity theft each year.
Of those uses who have installed anti-malware, the majority use free software (give thought to how the developer is monetizing their "free" software), or substandard software. Yes, there are plenty of commercial anti-malware applications that actually decrease your security, instead of improving it!
I've written a number of blogs on how to find the right anti-malware for your environment. But I'll save you time reading.
Bitdefender is consistently rated among the top products available. That's the good news. The bad news is they have so many different versions, it is difficult to figure out which to purchase. I'll save you more time reading. My universal recommendation–for the individual home user, small business, up through the enterprise business–is Bitdefender GravityZone. Please don't mistake this for Bitdefender Central, Total Security, or their other consumer-level offerings. This is the real-deal for the most comprehensive protection.
However, Bitdefender GravityZone requires a minimum of 3 licenses, and a deep level of configuration. This puts it beyond the reach of the individual user, family, or small business. Until now.
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MintzIT will even customize your Bitdefender configuration to meet your unique needs. And although you probably won't need it, we can even remotely install it for you.


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class CreateBlocks < ActiveRecord::Migration
  def change
    create_table :blocks do |t|
      t.string :title, null: false
      t.integer :user_id, null: false

      t.timestamp
    end
  end
end

redpajama_set_name: RedPajamaGithub


July 14, 2017, Vancouver, BC – StrikePoint Gold Inc. (SKP:TSX.V)(STKXF:OTCQB) ("StrikePoint" or the Company) is pleased to report on the progress of its $2.5M summer gold exploration program in the Yukon. Comprehensive work including drilling has been completed on the Mahtin property. The crew is now working on the Pluto property judged to be Strikepoint's highest ranked target. Exploration is also planned this season for several other targets.
The Pluto Gold Project is located approximately 100km west-southwest of the town of Carmacks in the central Yukon Territory. The StrikePoint Team have established their camp and are currently undertaking a mapping and sampling program, with drilling due to start on or around July 16th. Two main targets have been identified for exploration work, the northern "Charon" target and the southern "Hydra" zone.
The Pluto property is in the Kluane region, and is one of the largest in StrikePoint's portfolio, approximately 40 x 30km in size. Pluto sits relatively close to the latest discoveries in the White Gold district, and is aligned along strike with this group of projects. However, initial analysis of the geology seems to show a unique mineralizing style for the area; the formation of skarns in contact with large, regional 'ring' dyke volcanic features.
StrikePoint Gold also took part in the First Nations of the Na-Cho Nyak Dun 'Industry Day' on June 25th, presenting to the Council and Community the Mahtin and Golden-Oly projects which lie within their traditional territories.


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Edem Trends GH
Home Entertainment 6 Ghanaian musicians in America (United States)
6 Ghanaian musicians in America (United States)
edemtrends
In today's edition, we will look at Six (6) Ghanaian musicians in America.
There are musicians because they were born in the United States are regarded American musicians. But possibly have an a Ghanaian descent that we had no idea of and in this write up we will show you a number of them.
Some of these musicians are from a mixed background with either a parent or both parents from Ghana and that makes them have the Ghanaian blood as well.
READ ALSO: 20 Years Old Kumawood Actress Maame Serwaa, Drops Another Video Shaking Her Attractive Body
A number of them since they were born outside haven't found time to come down and have a feel of how Ghana looks like but there are others who have visited and even hangouts with high-profile persons in Ghana.
The amazing part is that Ghanaians living home become very excited for these stars hearing them make waves in the industry which they find themselves and are gaining recognitions for their hard work.
Again, there are some who have worked on big projects and winning some ultimate international Awards and as well hearing this makes us feel proud of them due to the fact that their some how raising the name of Ghana high through their music.
Below is a list of Ghanaian musicians in America/American musicians with a Ghanaian descent. There might be a tall list of them, but we bring you just six (6) Ghanaian musicians in America;
1. Vic Mensa
Victor Kwesi Mensah better known as Vic Mensa is a renowned American rapper, singer and an activist. He was born in Chicago, Illinois, in the United States and currently based in the states. He is of a Ghanaian descent as his father is from Ghana and his mother, a white American.
He is into hip hop and punk rap as a music genre and have paid a visit to Ghana and had collaborations with popular Ghanaian artistes like Kwesi Arthur, Stonebwoy, Sarkodie and among others.
2. V.I.C.
Victor Grimmy Owusu known by the stage name V.I.C. is an American rapper who was born in Corona, Queens, the United States.
He is also of a Ghanaian descent as his dad is a Ghanaian and his mother is from the states.
3. Amaarae
Ama Serwaa Genfi known by the stage name Amaarae, is a Ghanaian American singer, a producer and sound engineer. She was born the United States and currently one of the Ghanaian musicians based overseas.
She has both parents to be Ghanaians, and she's into music genres like R & B, Afro-fusion and soul.
4. Yarzarah
Yarzarah known in real life as Dana Nicole Amma Williams is a Ghanaian American singer, songwriter and music producer. She was born to a Ghanaian father and currently lives in the United States.
She makes music genres like soul music, R & B, Rock and others.
5. Moses Sumney
Moses Sumney is a Ghanaian American Singer, instrumentalist and a song writer who was born in the United States and has been in the music Industry since 2014.
He also makes Alternative/Indie and Folk music genres.
6. Lil Tjay
Tione Jayden Merritt is an American rapper, singer and songwriter. He derived his stage name from his real name, and he also has a Ghanaian descent.
Tjay was born in Bronx, New York, the United States to a Ghanaian mother and makes trap, drill and hip hop music.
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Bill E Daly gives us a soulful introduction to his music with 'Hey Baby Hey'
Americana-tinged modern folk is the order of the day from Dublin's Bill E Daly with this, from his new EP 'Parachute & Oxygen'. 'Hey Baby Hey' is a gentle acoustic-guitar-and-vocal love song with a catchy little chord progression and Daly's deep baritone voice. Tinged with country and modern rock overtones, this is mature, well-polished, and accomplished, little guitar flourishes on the ends of lines interplaying with Daly's chilled vocal delivery.
Daly's previous album, 2017's 'There Is A Time', charted at number 2 in Google Play's 'Folk' category, and there's every chance that 'Parachute & Oxygen' will do similarly well. 'Hey Baby Hey' is the ideal introduction to Bill E Daly's music.
Hear 'Hey Baby Hey' on Spotify; check out Daly's website here.
Review by Alex Holmes
Alt Indie Rock artist Tom Morris invites you to share 'The Dark Hours' with him through his debut release
https://tommorris.bandcamp.com/track/the-dark-hours
Like many artists, Scottish singer-songwriter Tom Morris released his debut single, The Dark Hours', this summer, but unlike most new releases, the soundscape exhibited the artist's prowess when it comes to instilling overwhelming emotion as the track becomes so much more than the sum of all parts.
The moody hints of 80s Electro hum around the intricate bluesy indie rock guitars while Tom Morris crafts one of the most infectious vocal melodies I've heard this year.
No artist carries the influence of Kurt Vile without picking up the hypnotically mellifluous textures of his meanderingly enticing guitar, which is exactly what is on offer in The Dark Hours which captures the agony of those twilight hours when your body loses most of its capacity for function while your mind runs rampant through every avenue for melancholy.
When I first hit play, I was intrigued by the stylistic collision of genres, by the time The Dark Hours faded out, I was overcome by the artist's invaluable ability to alchemically offer compassion and comfort through relaying his own bitter-sweet introspection.
You can find out more about Tom Morris by heading over to his official website.
Head over to Bandcamp to stream and download The Dark Hours.
More Than Skies – Tomorrow Won't Bother: Psychedelically Cinematic Angsty Folk Rock
More Than Skies is the project of New York singer-songwriter Adam James. With two EP's and a self-released double-album since its inception in 2006, James now drops his new album, 'Tomorrow Won't Bother', leading off with this, the title track.
Perhaps best described as mildly psychedelic-sounding angsty folk-rock, 'Tomorrow Won't Bother' has a distinctly Beatles-y vibe to it, all beautiful wavering strings, strummed acoustic guitar, and a hugely classy piano-led intro, all held together by James' effortless vocal. There's a pizzicato element to the strings adding some percussive drive to the middle section, a charmingly 'Leslie Cabinet' dopplering tremolo effect to James' voice, and that delicious piano intro and outro, all adding serious class to an already beautifully crafted and performed track. 'Tomorrow Won't Bother' is the perfect taster.
Hear 'Tomorrow Won't Bother' on Spotify; check out More Than Skies on Facebook.
Logan Bolan offers delicately provocative Stonesy tones with "Flower"
Earlier this year, Californian singer-songwriter Logan Bolan released their evocatively bluesy Indie rock single "Flower", it may be instrumentally minimalistic, but you can expect the entirety of your attention to fall under the command of this deeply sentimental single.
It is easily one of the most reflectively poignant singles we've heard in 2020. It's the kind of track you'll hit repeat on for the efficacious way in which it guides you through your own introspection.
Those sweet Stonesy tones under ardent new contortion allow you to slip into the escapism offered by the Rolling Stones while Logan allows you to breathe in the contemporary provocative air of the soundscape through their soul-bearing vocals.
You can check out the official music video to Flower by heading over to YouTube.
C. Moore Music mashes up the Alt 90s sound with "Knockin' Around"
https://cmooremusic.bandcamp.com/track/knockin-around
NYC Folk Punk singer-songwriter and multi-instrumentalist C. Moore Music left us instantly enamoured with their genre-mashing single 'Knockin' Around' which featured on their 11th solo record 'Unruly'.
He may be a prolific artist, but Knockin Around proves that quantity never comes before quality by boasting transfixingly arrestive hooks right from the intro. The dynamic soundscape may see many of evolutions as it progresses, but your attention will never be in danger of faltering from the grungy almost tribalistic momentum which ebbs and flows in this stunningly crafted single.
With a vocal vibrato which would give Eddie Vedder a run for his money and a freshly sonic smorgasbord of Psych, Blues and Folk on offer instrumentally, Knockin' Around doesn't just revive what previous artists allowed us to fall in love with. He brings nostalgic aural elements into a contemporary realm with his own signature sound which will be a hit with any fans of Dinosaur Jr, Pavement and The Jesus and Mary Chain.
You can check out C. Moore Music's single Knockin' Around via Bandcamp.
The Be Colony – Free at Last: Mellifluously Ascension-Aiding Rock
There are few things sweeter than freedom, one of them is the seminal single by up and coming Alt Folk Rock trailblazers The Be Colony.
Free at Last has a mellifluously ascension-aiding feel which is perfectly paired with the enlightened lyricism which will allow you to melt into your own introspection. The shimmering choral tones give Free at Last a celestial and psychedelic vibe as the Old School Alt Folk Blues instrumentals chime and groove through the progressions. As the track evolves, the band's virtuosic skill starts to shine even brighter as the intricate solos leave you transfixed in pure soulful alchemy.
You can check out The Be Colony's standout track Free at Last by heading over to YouTube
Orange Animal – Here I See: Soulfully Compelling Semi-Orchestral Alt Rock
Here I See is the latest single to be released from US Alt-Rock artist Orange Animal. Their visceral combination of Blues, Rock and Folk in Here I See offers the kind of sound which the word 'phenomenal' should be reserved for.
The energy and the atmosphere allow you to almost forget that you're listening to what started out as a melody and some lyrics. Their ingenuity brings rare intensity to the aural experience which won't fail to leave you arrested. You lock into the resonance which spills from the all too compelling, low, gravelly vocals and the angular precision of the guitar notes as they lead the way through the semi-orchestral single.
It's as stylistic and as contemporary as what you'd expect to hear from the likes of the National, but the roots of each of the genres which were weaved into the evocative mix are still audible. In short, I can't see any Rock-inclined music fan being unimpressed with Here I See.
If you're aurally sensitive, be prepared to feel a little bruised by this soulfully compelling melodic masterpiece.
You can check out Orange Animal's single for yourselves by heading over to Spotify.
The Asbury Park Love Contingent have released their upliftingly essential charity single "Lay Down"
All too often, uplifting music resonates as trite, but The Asbury Park Love Contingent's charity single "Lay Down (Candles in the Rain)" which was recorded and produced during lockdown is served straight from the soul. It won't fail to soothe your own either.
You can practically consider hitting play on Lay Down as an act of self-care for the tension and anxiety it will strip away with the choral accordance, sincerity, and absolving ingenuity.
Karen Mansfield, Emily Grove and Tara Dente's vocals never fail to leave an impression, Karen has also been on our radar since 2018 with her uniquely compelling solo work. But with her new-formed band The Asbury Park Love Contingent, her sound is even more captivating before. With Steve Greenwell (Joss Stone) in charge of production, the powerful feat of celestial Pop Rock was never going to fall flat.
Lay Down wasn't just originally written and originally performed by Melanie Safka with the intention of sharing positivity and love, it has also now been released as a charity record. All proceeds from the single will go to The Jersey Shore Rescue Mission in Asbury Park, NJ, which provides food, clothing and shelter to the homeless.
You can check out the upliftingly essential single for yourselves by heading over to SoundCloud now.
UK Folk Singer-Songwriter Fabio Whyte Has Released Their Latest Masterfully Arrestive Single "Misty Words"
UK Folk Rock Singer-Songwriter Fabio Whyte has recently released their accordantly adrenalizing latest single "Misty Words". If you're looking for an aural pick me up which drips with ardent sincerity, look no further.
With the first few acoustic guitar notes, the infectious energy contained in Misty Words starts to resonate. From there on out you're hooked in an upbeat Alt Folk earworm.
Don't let Fabio Whyte's flirtation with the Folk genre fool you, their intricately absorbing melodies aren't a long way off what you can expect from Elliott Smith's fretboard mastery. But instead of misery, you'll get organic uplifting vibes from Misty Words. The track may tackle the subject of romantic mishaps, but it's hard to feel downbeat while you're listening to the progressively beguiling single unfold.
You can check out Fabio Whyte's single Misty Words by heading over to Soundcloud now.
Nate Wilkinson is set to release their resounding Alt Folk Rock single "Better Days"
We've been lucky enough to get a sneak preview of up and coming Alt Folk Rock artist Nate Wilkinson's upcoming single "Better Days". It's safe to say that the airwaves are in for a potent infusion of sincerity when the passionately masterful soundscape drops.
With vocals and intricate guitar work which could give James Dean Bradfield a run for their money, Better Days is not only a deftly-crafted feat of Rock. The visceral intensity makes it so much more. I'm always of the opinion that lyricism should be striking and unapologetically honest, Better Days is one of the rare tracks which doesn't disappoint.
By all definition, Better Days is a captivating hit. Whether you're a Folk fan or have a penchant for the raucous licks in Rock, you'll want Nate Wilkinson on your radar.
Better Days is due for release on July 10th. You'll be able to check it out for yourselves via SoundCloud. In the meantime, you can check out Nate Wilkinson's other optimism-inspiring tracks.


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Home » Wasser lab receives IPR Center's 2020 Partnership Award
Wasser lab receives IPR Center's 2020 Partnership Award
Friday, November 20, 2020 - 09:45 to Saturday, February 20, 2021 - 09:45
Sam Wasser's Center for Conservation Biology at the University of Washington was recently honored by the National Intellectual Property Rights Coordination Center (IPR Center) as one of 32 recipients of its 2020 Partnership Awards. The award was in recognition of their collaborative work to combat transnational environmental crime.
Awards were presented to 32 organizations, including private sector companies, academic institutions and advocacy organizations, in seven categories: Operation Stolen Promise, E-Commerce Working Group, Sustained Partnerships, Evolving Partnerships, Operational Support, Trade Fraud Enforcement, and Counter-Proliferation Enforcement. Organizations were honored for their work, dedication and shared commitment to safeguarding national and economic security, combating illicit trade, and protecting the health and safety of the American public.
Read the full announcement here.
Congratulations to Sam and the Center for Conservation Biology!
Conservation Biology, Ecology, Physiology
Samuel K-Wasser


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Home Content Index Books of the Bible Psalms Out of the miry clay
What does it mean that He brought me out of the miry clay (Psalm 40:2)?
King David discovered a key to experiencing joy amid the most challenging times of life by remembering God's past deliverance from trouble. We don't know the exact details of David's ordeal in Psalm 40, but he compares it to being stuck in a horrifying pit filled with mud and mire:
"I waited patiently for the LORD;
And He inclined to me,
And heard my cry.
He also brought me up out of a horrible pit,
Out of the miry clay,
And set my feet upon a rock,
And established my steps" (Psalm 40:1–2, NKJV).
If you've ever been stuck in quicksand or stood on the soft ocean shore as your feet sank deeper into the sand with each wave, you know the feeling of being caught in the staggering helplessness of miry clay. Mire is deep, soft mud in water or slush, like wet loam or potter's clay. The Hebrew term in Psalm 40:2 is translated as "miry bog" (ESV), "mud and mire" (NIV), and "muddy clay" (CSB).
David wants to convey the idea of being desperately trapped in abysmally dark circumstances. David's metaphor reminds us of Jeremiah's actual imprisonment in a muddy cistern (Jeremiah 38:7–13) and Joseph's entrapment by his brothers in a pit (Genesis 37:18–22). On his own, David is powerless to escape. The only thing he can do is wait patiently for the Lord to rescue him. David may have been speaking of the same excruciating episode in Psalm 69:2: "Deeper and deeper I sink into the mire; I can't find a foothold. I am in deep water, and the floods overwhelm me" (NLT).
David's pit of miry clay could be symbolic of any number of distressing times he endured. Perhaps it was the crater of depression and rejection he experienced due to King Saul's murderous jealously and hatred (1 Samuel 18:10–17; 23:15–29). Maybe it was the time his son Absolom led a conspiracy and rebellion against him (2 Samuel 15:1—18:33). It might have been the pit David dug for himself through his sinful affair with Bethsheba and then the slaying of her husband (2 Samuel 11:1–27).
Whatever the pit may have been, David has learned in times of trouble to cry out to the Lord: "Rescue me from the miry mud; don't let me sink. Let me be rescued from those who hate me and from the deep water" (Psalm 69:14, CSB). As he trusts in the Lord and calls on God for help, David's Redeemer hears and answers (Psalm 56:9–11; 121:1–2).
"He brought me out of the miry clay," testifies David. The Lord delivers him by pulling him up and out of his horrible ordeal. "You brought me up from the grave, O LORD," utters David in Psalm 30:3, "You kept me from falling into the pit of death" (NLT). "He brought me out into a spacious place; he rescued me because he delighted in me," declares David in Psalm 18:19. What David cannot do for himself, the Lord accomplishes (see Ephesians 3:20; Luke 18:27). God sets David's feet on a solid, secure rock and establishes his steps (Psalm 27:5; 37:23; 62:2).
He brought me out of the miry clay is also a picture of Jesus Christ's death, burial, and resurrection and the resulting salvation believers experience through Him. When Jesus Christ died, He was buried in the grave. Crucifixion was a truly "horrible pit" as the spotless Lamb of God took all the transgressions of humankind on His sinless body (Isaiah 53:4–5; 1 John 3:5).
But, thanks be to God, our Savior did not stay in the pit. "God raised him from the dead, freeing him from the agony of death, because it was impossible for death to keep its hold on him" (Acts 2:24; see also Hebrews 5:7). He was brought "out of the miry clay." Christ is alive now and lives forever. The apostle Peter explains, "He suffered for our sins once for all time. He never sinned, but he died for sinners to bring you safely home to God. He suffered physical death, but he was raised to life in the Spirit" (1 Peter 3:18, NLT).
Jesus Christ was raised to life, never to die again. His work of redemption is complete. We were destined to die, but through His marvelous salvation, He brought us out of the miry clay. He set our feet upon a rock, and like David, He put a new song of praise to God in our mouths (Psalm 96:1; 149:1).
For Further Study
Book of Psalms: New International Commentary on the Old Testament by deClaisse-Walford, Jacobson, & Tanner
More insights from your Bible study - Get Started with Logos Bible Software for Free!
What does it mean that the Lord "set my feet upon a rock" (Psalm 40:2)?
What does it mean to delight yourself in the Lord (Psalm 37:4)?
What does it mean to commit your way to the Lord (Psalm 37:5)?
Does Psalm 49:7 mean that Jesus could not have redeemed us on the cross?
What are the rod and staff in Psalm 23?
Questions about Psalms
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