text:
Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells
Ryan A. Wilcox, David A. Wada, Steven C. Ziesmer, Sherine F. Elsawa, Nneka I. Comfere, Allan B Dietz, Anne J Novak, Thomas Elmer Witzig, Andrew L Feldman, Mark R. Pittelkow, Stephen Maxted Ansell
Laboratory Medicine and Pathology
A variety of nonmalignant cells present in the tumor microenvironment promotes tumorigenesis by stimulating tumor cell growth and metastasis or suppressing host immunity. The role of such stromal cells in T-cell lymphoproliferative disorders is incompletely understood. Monocyte-derived cells (MDCs), including professional antigen-presenting cells such as dendritic cells (DCs), play a central role in T-cell biology. Here, we provide evidence that monocytes promote the survival of malignant T cells and demonstrate that MDCs are abundant within the tumor microenvironment of T cell-derived lymphomas. Malignant T cells were observed to remain viable during in vitro culture with autologous monocytes, but cell death was significantly increased after monocyte depletion. Furthermore, monocytes prevent the induction of cell death in T-cell lymphoma lines in response to either serum starvation or doxorubicin, and promote the engraftment of these cells in nonobese diabetic/severe combined immunodeficient mice. Monocytes are actively recruited to the tumor microenvironment by CCL5 (RANTES), where their differentiation into mature DCs is impaired by tumor-derived interleukin-10. Collectively, the data presented demonstrate a previously undescribed role for monocytes in T-cell lymphoproliferative disorders.
https://doi.org/10.1182/blood-2009-05-220111
Lymphoproliferative Disorders
T-Cell Lymphoma
Chemokine CCL5
SCID Mice
Wilcox, R. A., Wada, D. A., Ziesmer, S. C., Elsawa, S. F., Comfere, N. I., Dietz, A. B., ... Ansell, S. M. (2009). Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells. Blood, 114(14), 2936-2944. https://doi.org/10.1182/blood-2009-05-220111
Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells. / Wilcox, Ryan A.; Wada, David A.; Ziesmer, Steven C.; Elsawa, Sherine F.; Comfere, Nneka I.; Dietz, Allan B; Novak, Anne J; Witzig, Thomas Elmer; Feldman, Andrew L; Pittelkow, Mark R.; Ansell, Stephen Maxted.
In: Blood, Vol. 114, No. 14, 2009, p. 2936-2944.
Wilcox, RA, Wada, DA, Ziesmer, SC, Elsawa, SF, Comfere, NI, Dietz, AB, Novak, AJ, Witzig, TE, Feldman, AL, Pittelkow, MR & Ansell, SM 2009, 'Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells', Blood, vol. 114, no. 14, pp. 2936-2944. https://doi.org/10.1182/blood-2009-05-220111
Wilcox RA, Wada DA, Ziesmer SC, Elsawa SF, Comfere NI, Dietz AB et al. Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells. Blood. 2009;114(14):2936-2944. https://doi.org/10.1182/blood-2009-05-220111
Wilcox, Ryan A. ; Wada, David A. ; Ziesmer, Steven C. ; Elsawa, Sherine F. ; Comfere, Nneka I. ; Dietz, Allan B ; Novak, Anne J ; Witzig, Thomas Elmer ; Feldman, Andrew L ; Pittelkow, Mark R. ; Ansell, Stephen Maxted. / Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells. In: Blood. 2009 ; Vol. 114, No. 14. pp. 2936-2944.
@article{c194978e1ec74f75b35ee7b4e7137bd8,
title = "Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells",
abstract = "A variety of nonmalignant cells present in the tumor microenvironment promotes tumorigenesis by stimulating tumor cell growth and metastasis or suppressing host immunity. The role of such stromal cells in T-cell lymphoproliferative disorders is incompletely understood. Monocyte-derived cells (MDCs), including professional antigen-presenting cells such as dendritic cells (DCs), play a central role in T-cell biology. Here, we provide evidence that monocytes promote the survival of malignant T cells and demonstrate that MDCs are abundant within the tumor microenvironment of T cell-derived lymphomas. Malignant T cells were observed to remain viable during in vitro culture with autologous monocytes, but cell death was significantly increased after monocyte depletion. Furthermore, monocytes prevent the induction of cell death in T-cell lymphoma lines in response to either serum starvation or doxorubicin, and promote the engraftment of these cells in nonobese diabetic/severe combined immunodeficient mice. Monocytes are actively recruited to the tumor microenvironment by CCL5 (RANTES), where their differentiation into mature DCs is impaired by tumor-derived interleukin-10. Collectively, the data presented demonstrate a previously undescribed role for monocytes in T-cell lymphoproliferative disorders.",
author = "Wilcox, {Ryan A.} and Wada, {David A.} and Ziesmer, {Steven C.} and Elsawa, {Sherine F.} and Comfere, {Nneka I.} and Dietz, {Allan B} and Novak, {Anne J} and Witzig, {Thomas Elmer} and Feldman, {Andrew L} and Pittelkow, {Mark R.} and Ansell, {Stephen Maxted}",
doi = "10.1182/blood-2009-05-220111",
journal = "Blood",
publisher = "American Society of Hematology",
T1 - Monocytes promote tumor cell survival in T-cell lymphoproliferative disorders and are impaired in their ability to differentiate into mature dendritic cells
AU - Wilcox, Ryan A.
AU - Wada, David A.
AU - Ziesmer, Steven C.
AU - Elsawa, Sherine F.
AU - Comfere, Nneka I.
AU - Dietz, Allan B
AU - Novak, Anne J
AU - Witzig, Thomas Elmer
AU - Feldman, Andrew L
AU - Pittelkow, Mark R.
AU - Ansell, Stephen Maxted
N2 - A variety of nonmalignant cells present in the tumor microenvironment promotes tumorigenesis by stimulating tumor cell growth and metastasis or suppressing host immunity. The role of such stromal cells in T-cell lymphoproliferative disorders is incompletely understood. Monocyte-derived cells (MDCs), including professional antigen-presenting cells such as dendritic cells (DCs), play a central role in T-cell biology. Here, we provide evidence that monocytes promote the survival of malignant T cells and demonstrate that MDCs are abundant within the tumor microenvironment of T cell-derived lymphomas. Malignant T cells were observed to remain viable during in vitro culture with autologous monocytes, but cell death was significantly increased after monocyte depletion. Furthermore, monocytes prevent the induction of cell death in T-cell lymphoma lines in response to either serum starvation or doxorubicin, and promote the engraftment of these cells in nonobese diabetic/severe combined immunodeficient mice. Monocytes are actively recruited to the tumor microenvironment by CCL5 (RANTES), where their differentiation into mature DCs is impaired by tumor-derived interleukin-10. Collectively, the data presented demonstrate a previously undescribed role for monocytes in T-cell lymphoproliferative disorders.
AB - A variety of nonmalignant cells present in the tumor microenvironment promotes tumorigenesis by stimulating tumor cell growth and metastasis or suppressing host immunity. The role of such stromal cells in T-cell lymphoproliferative disorders is incompletely understood. Monocyte-derived cells (MDCs), including professional antigen-presenting cells such as dendritic cells (DCs), play a central role in T-cell biology. Here, we provide evidence that monocytes promote the survival of malignant T cells and demonstrate that MDCs are abundant within the tumor microenvironment of T cell-derived lymphomas. Malignant T cells were observed to remain viable during in vitro culture with autologous monocytes, but cell death was significantly increased after monocyte depletion. Furthermore, monocytes prevent the induction of cell death in T-cell lymphoma lines in response to either serum starvation or doxorubicin, and promote the engraftment of these cells in nonobese diabetic/severe combined immunodeficient mice. Monocytes are actively recruited to the tumor microenvironment by CCL5 (RANTES), where their differentiation into mature DCs is impaired by tumor-derived interleukin-10. Collectively, the data presented demonstrate a previously undescribed role for monocytes in T-cell lymphoproliferative disorders.
U2 - 10.1182/blood-2009-05-220111
DO - 10.1182/blood-2009-05-220111
JO - Blood
JF - Blood
10.1182/blood-2009-05-220111


Chris Roelfsema is scientist/lecturer at University of Queensland since 1998. His research focuses on integrating field and remote sensing satellite or airborne imagery to study coral reef and seagrass environments. As a result, he gained knowledge and skills in: marine biology; identification of coral, seagrass, algae, and inverts; and various marine surveying methods and developed techniques for gathering georeferenced photos of bottom types.
For the research he mapped or monitored rocky reefs, seagrass and coral reefs in: Australia (e.g. Moreton Bay Marine Park, Wolf Rock, Heron Reef, Lizard, Swains, Coral Sea), and Asia Pacific (e.g. Fiji, Cook Island, Solomon's, Palau). Chris has various degrees: BsC hydrographic surveying, MsC Geodetic Engineer, PgDip Marine Science and PhD in coral reef remote sensing. Since 1981 he has been an active diver, and has trained people in all kinds of diving and first aid skills. He has trained people in various marine surveying methods, organised volunteer based marine monitoring projects, is active supporter of Reef Check and CoralWatch, and is Reef Check trainer since 2010.


text:
package net.bither.bitherj.crypto;

import net.bither.bitherj.crypto.bip38.Bip38;
import net.bither.bitherj.exception.AddressFormatException;
import net.bither.bitherj.utils.Utils;

import org.junit.Test;

import java.io.UnsupportedEncodingException;

import static org.junit.Assert.assertEquals;
import static org.junit.Assert.assertTrue;

public class Bip38Test {

    @Test
    public void testEncryptNoCompression() throws InterruptedException, AddressFormatException {
        String encoded = Bip38.encryptNoEcMultiply("TestingOneTwoThree",
                "5KN7MzqK5wt2TP1fQCYyHBtDrXdJuXbUzm4A9rKAteGu3Qi5CVR");
        assertEquals(encoded, "6PRVWUbkzzsbcVac2qwfssoUJAN1Xhrg6bNk8J7Nzm5H7kxEbn2Nh2ZoGg");
        assertTrue(Bip38.isBip38PrivateKey(encoded));
    }

    @Test
    public void testDecryptNoCompression() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("6PRVWUbkzzsbcVac2qwfssoUJAN1Xhrg6bNk8J7Nzm5H7kxEbn2Nh2ZoGg",
                "TestingOneTwoThree");
        assertEquals(decoded.toString(), "5KN7MzqK5wt2TP1fQCYyHBtDrXdJuXbUzm4A9rKAteGu3Qi5CVR");
    }

    @Test
    public void testDecryptNoCompressionWithBom() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("\uFEFF6PRVWUbkzzsbcVac2qwfssoUJAN1Xhrg6bNk8J7Nzm5H7kxEbn2Nh2ZoGg",
                "TestingOneTwoThree");
        assertEquals(decoded.toString(), "5KN7MzqK5wt2TP1fQCYyHBtDrXdJuXbUzm4A9rKAteGu3Qi5CVR");
    }

    @Test
    public void testEncryptCompression1() throws InterruptedException, AddressFormatException {
        String encoded = Bip38.encryptNoEcMultiply("TestingOneTwoThree",
                "L44B5gGEpqEDRS9vVPz7QT35jcBG2r3CZwSwQ4fCewXAhAhqGVpP");
        assertEquals(encoded, "6PYNKZ1EAgYgmQfmNVamxyXVWHzK5s6DGhwP4J5o44cvXdoY7sRzhtpUeo");
        assertTrue(Bip38.isBip38PrivateKey(encoded));
    }

    @Test
    public void testDecryptCompression1() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("6PYNKZ1EAgYgmQfmNVamxyXVWHzK5s6DGhwP4J5o44cvXdoY7sRzhtpUeo",
                "TestingOneTwoThree");
        assertEquals(decoded.toString(), "L44B5gGEpqEDRS9vVPz7QT35jcBG2r3CZwSwQ4fCewXAhAhqGVpP");
    }

    @Test
    public void testDecryptCompression1WithBom() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("\uFEFF6PYNKZ1EAgYgmQfmNVamxyXVWHzK5s6DGhwP4J5o44cvXdoY7sRzhtpUeo",
                "TestingOneTwoThree");
        assertEquals(decoded.toString(), "L44B5gGEpqEDRS9vVPz7QT35jcBG2r3CZwSwQ4fCewXAhAhqGVpP");
    }

    @Test
    public void testEncryptCompression2() throws InterruptedException, AddressFormatException {
        String encoded = Bip38.encryptNoEcMultiply("Satoshi", "KwYgW8gcxj1JWJXhPSu4Fqwzfhp5Yfi42mdYmMa4XqK7NJxXUSK7"
        );
        assertEquals(encoded, "6PYLtMnXvfG3oJde97zRyLYFZCYizPU5T3LwgdYJz1fRhh16bU7u6PPmY7");
        assertTrue(Bip38.isBip38PrivateKey(encoded));
    }

    @Test
    public void testDecryptCompression2() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("6PYLtMnXvfG3oJde97zRyLYFZCYizPU5T3LwgdYJz1fRhh16bU7u6PPmY7", "Satoshi");
        assertEquals(decoded.toString(), "KwYgW8gcxj1JWJXhPSu4Fqwzfhp5Yfi42mdYmMa4XqK7NJxXUSK7");
    }

    @Test
    public void testDecryptCompression2WithBom() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("\uFEFF6PYLtMnXvfG3oJde97zRyLYFZCYizPU5T3LwgdYJz1fRhh16bU7u6PPmY7", "Satoshi");
        assertEquals(decoded.toString(), "KwYgW8gcxj1JWJXhPSu4Fqwzfhp5Yfi42mdYmMa4XqK7NJxXUSK7");
    }

    @Test
    public void testDecryptNoCompressionWithEcMultiplyNoLot1() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("6PfQu77ygVyJLZjfvMLyhLMQbYnu5uguoJJ4kMCLqWwPEdfpwANVS76gTX",
                "TestingOneTwoThree");
        assertEquals(decoded.toString(), "5K4caxezwjGCGfnoPTZ8tMcJBLB7Jvyjv4xxeacadhq8nLisLR2");
    }

    @Test
    public void testDecryptNoCompressionWithEcMultiplyNoLot1WithBom() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("\uFEFF6PfQu77ygVyJLZjfvMLyhLMQbYnu5uguoJJ4kMCLqWwPEdfpwANVS76gTX",
                "TestingOneTwoThree");
        assertEquals(decoded.toString(), "5K4caxezwjGCGfnoPTZ8tMcJBLB7Jvyjv4xxeacadhq8nLisLR2");
    }

    @Test
    public void testDecryptNoCompressionWithEcMultiplyNoLot2() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("6PfLGnQs6VZnrNpmVKfjotbnQuaJK4KZoPFrAjx1JMJUa1Ft8gnf5WxfKd", "Satoshi");
        assertEquals(decoded.toString(), "5KJ51SgxWaAYR13zd9ReMhJpwrcX47xTJh2D3fGPG9CM8vkv5sH");
    }

    @Test
    public void testDecryptNoCompressionWithEcMultiplyNoLot2WithBom() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("\uFEFF6PfLGnQs6VZnrNpmVKfjotbnQuaJK4KZoPFrAjx1JMJUa1Ft8gnf5WxfKd", "Satoshi");
        assertEquals(decoded.toString(), "5KJ51SgxWaAYR13zd9ReMhJpwrcX47xTJh2D3fGPG9CM8vkv5sH");
    }

    @Test
    public void testDecryptNoCompressionWithEcMultiplyWithLot1() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("6PgNBNNzDkKdhkT6uJntUXwwzQV8Rr2tZcbkDcuC9DZRsS6AtHts4Ypo1j", "MOLON LABE");
        assertEquals(decoded.toString(), "5JLdxTtcTHcfYcmJsNVy1v2PMDx432JPoYcBTVVRHpPaxUrdtf8");
    }

    @Test
    public void testDecryptNoCompressionWithEcMultiplyWithLot1WithBom() throws InterruptedException, AddressFormatException {
        SecureCharSequence decoded = Bip38.decrypt("\uFEFF6PgNBNNzDkKdhkT6uJntUXwwzQV8Rr2tZcbkDcuC9DZRsS6AtHts4Ypo1j", "MOLON LABE");
        assertEquals(decoded.toString(), "5JLdxTtcTHcfYcmJsNVy1v2PMDx432JPoYcBTVVRHpPaxUrdtf8");
    }

    @Test
    public void testDecryptNoCompressionWithEcMultiplyWithLot2() throws InterruptedException, UnsupportedEncodingException, AddressFormatException {
        // "MOLON LABE" using greek characters  = "ΜΟΛΩΝ ΛΑΒΕ"
        String passphrase = "\u039C\u039F\u039B\u03A9\u039D \u039B\u0391\u0392\u0395";
        assertEquals("ce9cce9fce9bcea9ce9d20ce9bce91ce92ce95".toUpperCase(), Utils.bytesToHexString(passphrase.getBytes("UTF-8")));
        SecureCharSequence decoded = Bip38.decrypt("6PgGWtx25kUg8QWvwuJAgorN6k9FbE25rv5dMRwu5SKMnfpfVe5mar2ngH", passphrase);
        assertEquals(decoded.toString(), "5KMKKuUmAkiNbA3DazMQiLfDq47qs8MAEThm4yL8R2PhV1ov33D");
    }

    @Test
    public void testDecryptNoCompressionWithEcMultiplyWithLot2WithBom() throws InterruptedException, UnsupportedEncodingException, AddressFormatException {
        // "MOLON LABE" using greek characters  = "ΜΟΛΩΝ ΛΑΒΕ"
        String passphrase = "\u039C\u039F\u039B\u03A9\u039D \u039B\u0391\u0392\u0395";
        assertEquals("ce9cce9fce9bcea9ce9d20ce9bce91ce92ce95".toUpperCase(), Utils.bytesToHexString(passphrase.getBytes("UTF-8")));
        SecureCharSequence decoded = Bip38.decrypt("\uFEFF6PgGWtx25kUg8QWvwuJAgorN6k9FbE25rv5dMRwu5SKMnfpfVe5mar2ngH", passphrase);
        assertEquals(decoded.toString(), "5KMKKuUmAkiNbA3DazMQiLfDq47qs8MAEThm4yL8R2PhV1ov33D");
    }
}

redpajama_set_name: RedPajamaGithub


Cerro Prieto-Cerro la Luz Reserve has been extended by another 86.5 acres (35 hectares) thanks to World Land Trust (WLT).
The reserve is owned and managed by Grupo Ecológico Sierra Gorda (GESG), WLT's conservation partner in Mexico. In line with its policy to expand existing reserves rather than create new ones, GESG has been gradually increasing the area of Cerro Prieto-Cerro la Luz Reserve by buying up adjacent properties when they come on the market.
As well as funding land purchase to extend the reserve, WLT supports the employment of two rangers to patrol and protect the reserve. When left unprotected, the forests of Sierra Gorda are subject to illegal logging, which makes the rangers' vigilance – and WLT's Keepers of the Wild programme, which funds them – all the more essential.
The reserve consists of two peaks (Cerro Prieto and Cerro la Luz) with a distance of five kilometres between their highest points. The landscape is unusual with jagged limestone peaks and deep sinkholes and ancient oaks growing alongside agave and bromeliads in a mix of cloud forest and temperate forest.
The area has a rich botanical diversity with new species currently being described (Agavaceae, Cactaceae, Lentibulariaceae).
A number of rare species of mammals and birds are found in this area of Sierra Gorda Biosphere Reserve. Among them are Margay (Leopardus wiedii), classified by IUCN as Near Threatened; Bearded Wood-Partridge (Dendrortyx barbatus), classified as Vulnerable; and Maroon-fronted Parrot (Rhynchopsitta terrisi), classified as Endangered.
Also found in the area are two salamanders endemic to Mexico: Bell's False Brook Salamander (Pseudoeurycea bellii), classified as Vulnerable, and the Chunky False Brook Salamander (Pseudoerycea cephalica), classified as Near Threatened.
A donation to WLT's Buy an Acre appeal will help save more threatened habitat in Sierra Gorda.


text:
Q: 404 htaccess redirect is not working I am running tomcat on apache we server.
I am putting .htacces in project folder inside tomcat/webapps directory.
I am using following line inside .htaccess for 404 redirection
ErrorDocument 404 /404Redirect.html

But it is not working. Please let me know the location where i should place .htaccess or if i am doing mistake in redirection code

A: i had same problem. I solved it by adding RewriteEngine on before ErrorDocument 404 /404Redirect.html
please ensure that 404Redirect.html is in the same directory as the .htaccess file.

A: First check if you can use .htaccess file! Second your file(404Redirect.html) related to your document root NOT .htacsess  file!

redpajama_set_name: RedPajamaStackExchange


However, a lawsuit filed by the Comité interprofessionnel du vin de Champagne forced Saint Laurent to change the name in France. The fragrance was renamed Yves Saint Laurent and later Yvresse in 1996. In less than three months, Champagne became the third best-selling fragrance in Europe.
Yves Saint Laurent at the American launch of the fragrance Champagne, United States, September 1994. Photograph by Yann Gamblin.


DIGITAL.NEOSKOSMOS.COM THE WEEKEND NEOS KOSMOS | SATURDAY 21 MAY 2016 13 How connected are you to your Greek heritage? Very connected. Growing up, it was really important to my grandparents that they kept traditions alive, despite moving to the other side of the world. I still speak to my grandparents in Greek. Growing up, I went to Greek school so I'm able to speak and read without any problems. I think Greek music is the best - it does something to you that only other Greeks will understand. Are you a fan of Greek cuisine? I love Greek food! Most people think that Greek food is souvlaki and dips, but it's so much more than that. It's about fresh ingredients and doing as little as possible to the produce to give you the most flavour. Plus, we have some of the best desserts in the world. What made you give MasterChef a go? I wanted to do something for myself. Growing up, it was really important to my family that we go to a good school, study hard and get a good job so we don't have to work as hard as our parents had to. I went through uni and had a good job, but I'd always wanted to have a career in food. In my mind, MasterChef was my last opportunity to fulfil my dream before settling down and having children. What sets you apart from the other contestants? I think my palate is different. Being able to understand and use ingredients that I watched my yiayia use growing up, knowing what to do with them and how to use them is a massive bonus. Things like rosewater, mastic and a lot of different spices; most contestants either don't like those flavours or have never used those ingredients before. My grandparents are from Cyprus, so our food has a lot of influence from surrounding countries which helps me to think a little differently also. How different is cooking in front of a camera to at home or at work? Wow! It's completely different, but that also depends who I'm cooking for. If I'm at home cooking for my husband and I, he tends to not bother me when I'm in the kitchen. If I was at mum's or yiayia's house, now that's a different story! They're always giving me their input as to how I should do things in the kitchen, the 'right' way, which is yiayia's way. Where do you see yourself after the show? This is a really tough question because there's so much I want to do. But first off, I would love to start my own business that specialises in sweets. #watchthisspace What is your strength and your weakness in the kitchen? My strength is that I have a great knowledge of food, about flavours that do and don't work together and cooking techniques. I would say my weakness is that sometimes when I get an idea, I stick to it. The pressure of the kitchen at times gives you tunnel vision and you can't think about anything else once an idea pops into your head. Who do you think is the most 'dangerous' contestant? Definitely Matty, without a doubt. He is probably the best cook in the competition. His food is always delicious, consistent, well thought out and well executed. His food knowledge and skill are unbelievable, and to top it all off, he is probably the nicest guy you will ever meet! NICOLETTE STATHOPOULOS, 19, STUDENT Although she might be MasterChef Australia 2016's youngest contestant, Nicolette's talent should not be underestimated. Cooking seriously since she was aged 11, the 19-year-old and her older brother enjoyed a childhood filled with many happy memories and lots of food enjoyed with their extended Greek family. Having worked in a cake store for the past five years, Nicolette juggled her job with her high school studies, plus activities including rowing and kayaking. Graduating in 2014, she excelled in hospitality and food and technology. In 2015 she began her tertiary studies at Monash University, undertaking a double business degree, majoring in marketing and management, which she has deferred in order to take part in the competition. Despite her tender years, Nicolette has clocked up many kitchen hours by doing voluntary work experience in some of Melbourne's best restaurants, including Mr Wolf, Cutler & Co, Ginger Boy and Bistro Vue. She has also spent time in Adriano Zumbo's kitchen in Sydney and at age 16, even managed a day in the kitchen at Rene Redzepi's world-famous Noma restaurant in Copenhagen while on a family holiday after meeting him at a Melbourne book signing. Nicolette loves how food brings people together and sees this as being a big part of what she wants to do with her life. With her sights set on travel to Paris to study patisserie at Le Cordon Bleu, Nicolette would love to one day have a pop-up dessert bar in Melbourne. What is it that draws you to cooking? I've always loved cooking from a young age, since I can remember I was in the kitchen running around with my yiayia, helping her prepare dinner for the family. How connected are you to your Greek heritage? I love coming from a Greek background, it's something that has always connected me to family and food, especially around big celebrations such as Greek Easter and Christmas time. During Easter we always enjoy a week-long celebration that is filled with food and love. Are you a fan of Greek cuisine? I love Greek food, especially lots of meat. I'm fascinated by how food brings people together and the atmosphere. I go down to Oakleigh every couple of weeks and enjoy a coffee or mixed grilled meats with my friends I have gained through my Greek school years. What made you give MasterChef a go? I've been watching the show since it started. And I love a challenge - when I saw the auditions come out I just had to give it a go. Unfortunately, my grandfather passed away two weeks before auditions, which made me want to pursue MasterChef even more, to show him I can push myself and do something he would be proud of. What sets you apart from the other contestants? I am different to all the other contestants firstly because I am the youngest, but also for my personality and sense of humour. I'm probably considered the joker of the house, always cracking jokes. How different is cooking in front of a camera to at home or at work? At home I'm a lot more relaxed in the kitchen. I love cooking for big family gatherings so the portion sizes are very different. Where do you see yourself after the show? After the show I'd love to start running pop-up dessert bars showcasing my work on the show. What is your strength and your weakness in the kitchen? My strength in the kitchen is desserts, and my weakness would be seafood. Who do you think is the most 'dangerous' contestant? Everyone in the MasterChef kitchen has their strengths, and we all want to win, so we are all pretty dangerous at times.


text:
Q: Loop through certain files in batch I have a directory that contains .sql files like
file.xxx.v3.0.sql
file.xxx.v3.0.sql
file.xxx.v3.0.sql
file.xxx.v3.0.sql

In a .bat file how would I loop through all the files in a directory that start with "file." and end in ".v3.0.sql"?
So far I've got
for /f %%b in ('dir /b /s "%apppath%\files\*.sql"') do call :import %%b

A: This should work in your case:
for /f %%b in ('dir /b /s "%apppath%\files\file.*.v3.0.sql"') do call :import %%b

You can also use braces like this:
for /f %%b in ('dir /b /s "%apppath%\files\file.*.v3.0.sql"') do (
    call :import %%b
    ...
)

A: Forego the for /f route. There be dragons (for Unicode characters and spaces, especially – best not pick up any bad habits).
You can use plain old for, which can iterate over files just fine:
for %%b in (%apppath%\files\file.*.v3.0.sql) do (
  call :import %%b
)