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Cognitive versus emotional modulation within a Stroop paradigm in patients with schizophrenia
Verónica Romero-Ferreiro, Ana García-Gutiérrez, Iosune Torio, Paloma Marí-Beffa, Pablo Rodríguez-Gómez, José A. Periáñez, Eva M. Moreno, Carmen Romero, Miguel Ángel Alvarez-Mon, Roberto Rodriguez-Jimenez
Journal: BJPsych Open / Volume 9 / Issue 1 / January 2023
Published online by Cambridge University Press: 18 January 2023, e19
Schizophrenia is a complex disorder involving deficits in both cognitive and emotional processes. Specifically, a marked deficit in cognitive control has been found, which seems to increase when dealing with emotional information.
With the aim of exploring the possible common links behind cognitive and emotional deficits, two versions of the emotional Stroop task were administered.
In the cognitive-emotional task, participants had to name the ink colour (while ignoring the meaning) of emotional words. In contrast, the emotional-emotional task consisted of emotional words superimposed on emotional faces, and the participants had to indicate the emotional valence of the faces. Fifty-eight participants (29 in-patients diagnosed with schizophrenia and 29 controls) took part in the study.
Patients and controls showed similar response times in the cognitive-emotional task; however, patients were significantly slower than controls in the emotional-emotional task. This result supports the idea that patients show a more pronounced impairment in conflict modulation with emotional content. Besides, no significant correlations between the tasks and positive or negative symptoms were found. This would indicate that deficits are relatively independent of the clinical status of patients. However, a significant correlation between the emotional-emotional task and cognitive symptoms was found.
These findings suggest a restricted capacity of patients with schizophrenia to deal with the attentional demands arising from emotional stimuli.
Chapter 32 - Integrating Essential Public Health Functions in Health Systems
from Section 2 - Transforming Health Systems: Confronting Challenges, Seizing Opportunities
By Jose M. Martin-Moreno, Beatriz Lobo-Valbuena, Alejandro Martin-Gorgojo
Edited by Sameen Siddiqi, Aga Khan University, Awad Mataria, World Health Organization, Egypt, Katherine D. Rouleau, University of Toronto, Meesha Iqbal, UTHealth School of Public Health, Houston
Book: Making Health Systems Work in Low and Middle Income Countries
Essential public health functions (EPHF) are primary responsibility of the state and are fundamental for achieving public health goals through collective action. There are several EPHF frameworks that have core and enabling functions, which should be integrated within health systems. The preferred approach is to identify the framework that best suits the local context. International Health Regulation (IHR) are legally binding set of regulations meant to prevent international spread of diseases and are closely related to EPHF. EPHF focus on building capacity for public health nationally, while IHR respond to the obligations of public health globally. This Chapter makes a case for investing in public health as an obligation and an ethical and moral imperative of governments in every country by ensuring well performing EPHF and IHR.
I. Mexico
Alejandra Moreno Toscano, Manuel Alvarez Alvarez, Rosa María Sánchez de Tagle, Carlos Aguirre Anaya, María Dolores Morales, Sonia Lombardo de Ruiz, José Antonio Rojas
Journal: Latin American Research Review / Volume 10 / Issue 2 / Summer 1975
Published online by Cambridge University Press: 24 October 2022, pp. 117-131
El Seminario de Historia Urbana del Departamento de Investigaciones Históricas del INAH reune a un número variable de investigadores, de especialidades diversas, y a un grupo de estudiantes que reciben formación de investigación en historia urbana. La dirección del Seminario está a cargo de Alejandra Moreno Toscano, investigadora de El Colegio de México. El Seminario sobre Problemas Metodológicos en Historia Urbana de Agosto de 1974 tuvo como propósito principal, confrontar diversas investigaciones en curso, subrayando sus dificultades metodológicas.
Molecular epidemiology of paediatric invasive pneumococcal disease in Andalusia, Spain
Beatriz de Felipe, Pablo Obando Pacheco, Begoña Carazo Gallego, David López Martín, Juan Luis Santos Pérez, Yolanda González Jiménez, María José Muñoz Vilches, Nerea Cardelo Autero, Verónica González Galán, Francisco José Morón, Juan Antonio Cordero Varela, María José Torres Sánchez, Antonio Medina Claros, David Moreno Pérez, Ignacio Obando
Journal: Epidemiology & Infection / Volume 150 / 2022
Published online by Cambridge University Press: 22 August 2022, e163
This study aimed to assess the impact of the introduction of pneumococcal conjugate vaccine 13 (PCV13) on the molecular epidemiology of invasive pneumococcal disease (IPD) in children from Andalusia. A population-based prospective surveillance study was conducted on IPD in children aged <14 years from Andalusia (2018–2020). Pneumococcal invasive isolates collected between 2006 and 2009 in the two largest tertiary hospitals in Andalusia were used as pre-PCV13 controls for comparison of serotype/genotype distribution. Overall IPD incidence rate was 3.55 cases per 100 000 in 2018; increased non-significantly to 4.20 cases per 100 000 in 2019 and declined in 2020 to 1.69 cases per 100 000 (incidence rate ratio 2020 vs. 2019: 0.40, 95% confidence interval (CI) 0.20–0.89, P = 0.01). Proportion of IPD cases due to PCV13 serotypes in 2018–2020 was 28% (P = 0.0001 for comparison with 2006–2009). Serotypes 24F (15%) and 11A (8.3%) were the most frequently identified non-PCV13 serotypes (NVT) in 2018–2020. Penicillin- and/or ampicillin-resistant clones mostly belonged to clonal complex 156 (serotype 14-ST156 and ST2944 and serotype 11A-ST6521). The proportion of IPD cases caused by PCV13 serotypes declined significantly after the initiation of the PCV13 vaccination programme in 2016. Certain NVT, such as serotypes 24F and 11A, warrant future monitoring in IPD owing to invasive potential and/or antibiotic resistance rates.
TiN Coating and Fe2B Layer Obtained by PVD and Powder-pack Boriding Treatments Formed on ASTM A1011 Steel
Libia Daniella Fernández-De Dios, Arturo Cruz-Avilés, José Solis-Romero, María de la Luz Moreno-González, Georgina Moreno-González, Oscar Gómez-Vargas, Ángel Jesús Morales-Robles, Dulce María Trápala-Rosalio, Martín Ortiz-Domínguez
Journal: Microscopy and Microanalysis / Volume 28 / Issue S1 / August 2022
Published online by Cambridge University Press: 22 July 2022, pp. 1044-1046
Print publication: August 2022
Peace Came in the Sign of the Cross: Ritualized Diplomacy Among Natives and Spaniards in the Sonora-Arizona Borderlands, 1694–1836
José Manuel Moreno Vega
Journal: The Americas / Volume 79 / Issue 3 / July 2022
Published online by Cambridge University Press: 01 June 2022, pp. 399-424
Print publication: July 2022
This article analyzes the meanings and uses of crosses in the interactions among diverse indigenous groups and colonizers in the Sonoran frontier of northern New Spain during the eighteenth century and beyond. By showing that colonial expansion was a process that included persuasion within a context of violence, it highlights diplomacy through exchanges facilitated by cultural parallels and hybridity between Christian and precontact Amerindian symbols and rituals. This approach illustrates that the sign of the cross became a widespread mechanism for initiating peaceful interactions. The emphasis on the hybrid use of crosses provides insight into the fluid interactions among Natives and colonizers through the adoption of this symbol and the role these Native groups had in implanting colonial culture in their societies. Ultimately, it shows the indigenous peoples' reactions and strategies under colonial presence.
Habitat-dependent Culicoides species composition and abundance in blue tit (Cyanistes caeruleus) nests
Jorge Garrido-Bautista, Josué Martínez-de la Puente, José Luis Ros-Santaella, Eliana Pintus, Paula Lopezosa, Nicola Bernardo, Mar Comas, Gregorio Moreno-Rueda
Journal: Parasitology / Volume 149 / Issue 8 / July 2022
Published online by Cambridge University Press: 16 May 2022, pp. 1119-1128
Wild birds are hosts of Culicoides from as early on as the nesting stage when constrained to their nests. However, the environmental factors which determine the abundance and composition of Culicoides species within each bird nest are still understudied. We sampled Culicoides from Eurasian blue tit (Cyanistes caeruleus) nests found in 2 types of forests located in southern Spain. Firstly, we monitored the abundance of Culicoides species in bird nests from a dry Pyrenean oak deciduous forest and a humid mixed forest comprising Pyrenean and Holm oaks throughout 2 consecutive years. During the 3rd year, we performed a cross-fostering experiment between synchronous nests to differentiate the role of rearing environment conditions from that of the genetically determined or maternally transmitted cues released by nestlings from each forest. We found 147 female Culicoides from 5 different species in the birds' nests. The abundance of Culicoides was higher in the dry forest than in the humid forest. Culicoides abundance, species richness and prevalence were greater when the nestlings were hatched later in the season. The same pattern was observed in the cross-fostering experiment, but we did not find evidence that nestling's features determined by the forest of origin had any effect on the Culicoides collected. These results support the notion that habitat type has a strong influence on the Culicoides affecting birds in their nests, while some life history traits of birds, such as the timing of reproduction, also influence Culicoides abundance and species composition.
Rotational effect and dosimetric impact: HDMLC vs 5-mm MLC leaf width in single isocenter multiple metastases radiosurgery with Brainlab Elements™
Carlos Daniel Venencia, José Alejandro Rojas-López, Rogelio Manuel Díaz Moreno, Silvia Zunino
Journal: Journal of Radiotherapy in Practice / Volume 22 / 2023
Published online by Cambridge University Press: 22 April 2022, e35
To analyse the impact of multileaf collimator (MLC) leaf width in multiple metastases radiosurgery (SRS) considering the target distance to isocenter and rotational displacements.
Ten plans were optimised. The plans were created with Elements Multiple Mets SRS v2·0 (Brainlab AG, Munchen, Germany). The mean number of metastases per plan was 5 ± 2 [min 3, max 9], and the mean volume of gross tumour volume (GTV) was 1·1 ± 1·3 cc [min 0·02, max 5·1]. Planning target volume margin criterion was based on GTV-isocenter distance and target dimensions. Plans were performed using 6 MV with high-definition MLC (HDMLC) and reoptimised using 5-mm MLC (MLC-5). Plans were compared using Paddick conformity index (PCI), gradient index, monitor units , volume receiving half of prescription isodose (PIV50), maximum dose to brainstem, optic chiasm and optic nerves, and V12Gy, V10Gy and V5Gy for healthy brain were analysed. The maximum displacement due to rotational combinations was optimised by a genetic algorithm for both plans. Plans were reoptimised and compared using optimised margin.
HDMLC plans had better conformity and higher dose falloff than MLC-5 plans. Dosimetric differences were statistically significant (p < 0·05). The smaller the lesion volume, the higher the dosimetric differences between both plans. The effect of rotational displacements produced for each target in SRS was not dependent on the MLC (p > 0·05).
The finer HDMLC offers dosimetric advantages compared with the MLC-5 in terms of target conformity and dose to the surrounding organs at risk. However, only dose falloff differences due to rotations depend on MLC.
OP188 Post-Launch Evidence Generation Studies For Medical Devices In Spain: Integrating Real World Evidence Into Decision-Making
Inaki Imaz-Iglesia, Pedro Serrano, Eugenia Orejas, Anai Moreno, Janet Puñal-Ruibóo, Matilde Palma, Amado Rivero, M. Luisa Vicente-Sáiz, Eva Reviriego, Enrique Alcalde, Himar González, Iñaki Gutiérrez-Ibarluzea, Jesús González-Enríquez, José Asua, Asunción Gutiérrez, Lorea Galnares
Journal: International Journal of Technology Assessment in Health Care / Volume 37 / Issue S1 / December 2021
Published online by Cambridge University Press: 03 December 2021, pp. 4-5
A national act (Order SSI/1356/2015) regulating Post-Launch Evidence Generation (PLEG) studies was set in Spain in 2015. These PLEG studies are to inform decisions about technologies already included in the Benefit Portfolio of the Spanish National Health System (SNHS) in order to confirm/exclude/modify their terms of use. Once a PLEG is established the selected hospitals provide the technology according to a common protocol and register outcomes until the required sample size is reached.
The PLEG studies are prospective, observational and single arm studies on safety, effectiveness and cost-effectiveness of a technology in real practice. The technology is selected because of the identification of an evidence gap, usually through a health technology assessment (HTA) report made by an agency of the Spanish Network of HTA Agencies (RedETS). The execution of a PLEG is assigned to one of the RedETS Agencies, which is responsible of delivering annual reports and a final report when the objectives are reached.
The following six PLEG studies, all of them on medical devices, have been launched in Spain so far, i) Endobronchial valve for patients with persistent air leak; ii) Biodegradable esophageal stent; iii) Percutaneous mitral valve repair system by clip; iv) Left Atrial Appendage Closure Device; v) Sensor-based glucose monitoring systems for children with type 1 diabetes mellitus; vi) Left ventricular assist devices for destination therapy. Five studies will finish their data collection by the end of 2020 or during 2021.
A new national procedure using PLEG has been made available in Spain facilitating the use of real-world evidence to inform national decision-making on the financing of selected technologies due to uncertainties about their effectiveness, safety, cost-effectiveness and organizational impact. The studies are requiring a high amount of coordination tasks, as they are involving an average of 21 hospitals each. The usefulness and suitability of this procedure to achieve its objectives must be evaluated once their results are available.
El Niño Cave (Aýna, Albacete, Spain): Late Middle Palaeolithic, Rock Art, and Neolithic Occupations from Inland Iberia
Alejandro García-Moreno, Miriam Cubas, Iain Davidson, Diego Garate, Inés López-Dóriga, Ana B. Marín-Arroyo, Miguel Ángel Mateo Saura, José E. Ortiz, Ana Polo-Díaz, Joseba Rios-Garaizar, Aixa San Emeterio, Trinidad de Torres, Rachel Wood
Journal: Proceedings of the Prehistoric Society / Volume 87 / December 2021
Print publication: December 2021
El Niño cave, located on the south-eastern border of the Spanish Meseta, hosts a discontinuous sequence including Middle Palaeolithic and Neolithic levels, along with Upper Palaeolithic and Levantine style paintings. It is a key site for understanding human occupations of inland Iberia during the Palaeolithic and early prehistory. This paper summarises the main results of a multidisciplinary project aimed at defining the prehistoric human occupations at the site.
Hands Stencils in El Castillo Cave (Puente Viesgo, Cantabria, Spain). An Interdisciplinary Study
Sergio Ripoll, Vicente Bayarri, Francisco J. Muñoz, Ricardo Ortega, Elena Castillo, José Latova, Jesús Herrera, David Moreno-Salinas, Ignacio Martín
Our Palaeolithic ancestors did not make good representations of themselves on the rocky surfaces of caves and barring certain exceptions – such as the case of La Marche (found on small slabs of stone or plaquettes) or the Cueva de Ambrosio – the few known examples can only be referred to as anthropomorphs. As such, only hand stencils give us a real picture of the people who came before us. Hand stencils and imprints provide us with a large amount of information that allows us to approach not only their physical appearance but also to infer less tangible details, such as the preferential use of one hand over the other (i.e., handedness). Both new and/or mature technologies as well as digital processing of images, computers with the ability to process very high resolution images, and a more extensive knowledge of the Palaeolithic figures all help us to analyse thoroughly the hands in El Castillo cave. The interdisciplinary study presented here contributes many novel developments based on real data, representing a major step forward in knowledge about our predecessors.
An adaptation of meaning-centered psychotherapy integrating "essential care": A pilot study
E. Quílez-Bielsa, V. Barrado-Moreno, R. Lastra del Prado, José M. Arbonés-Mainar, M. Sebastian-Sanchez, T. Ventura-Faci
Journal: Palliative & Supportive Care / Volume 20 / Issue 4 / August 2022
Published online by Cambridge University Press: 28 September 2021, pp. 496-504
There is a growing interest in the emotional state of cancer patients. The main objective of this pilot study is to assess the feasibility, acceptability, and preliminary efficacy of Meaning-Centered Psychotherapy and Essential Care (MCP-EC) in patients with advanced cancer compared with usual psychological support. We define "Essential Care" as the promotion of patient care and self-care through the recall of good care experiences and discussion of the concepts: responsibility, self-compassion, kindness, and attitude.
Pilot, single-center, and prospective study of 30 patients with advanced cancer and emotional distress. Our adaptation consisted in three session Meaning-Centered Psychotherapy-Palliative Care, plus a fourth session named "Essential Care". The study was carried out in two phases. First, 20 patients were randomized to one of the two arms: individual MCP-EC (experimental, n = 10) or usual psychological supportive (control, n = 10). In a second phase, 10 patients were assigned consecutively to Group MCP-EC (n = 10). All patients were evaluated at baseline (pre-) and post-intervention with questionnaires for sociodemographic data and clinical scales.
Nineteen patients completed the 4 sessions of MCP-EC, 9 individual format and 10 group format. Usual supportive intervention was delivered to 10 control patients. Total 28 patients completed pre- and post-treatment evaluations. There were no pre- vs. post-differences in the evaluations of the control group. In the experimental group, significant pre- vs. post-differences were found in EQ-5D-3L, HADS, FACIT, DM, HAI, SCS-SF, and TD questionnaires. These results indicated that MCP-EC reduced anxiety and depression symptoms, hopelessness, demoralization, as well as increased spiritual well-being and sense of meaning. Participants were satisfied and found the MCP-EC intervention positively.
This pilot study suggests that the MCP-EC has feasibility, acceptability, and preliminary efficacy reducing the emotional distress in advanced cancer patients. Larger studies are warranted to clarify the strengths and limitations of this psychotherapy.
Assessment of Neurocognitive Functions, Olfaction, Taste, Mental, and Psychosocial Health in COVID-19 in Adults: Recommendations for Harmonization of Research and Implications for Clinical Practice
Lucette A. Cysique, Emilia Łojek, Theodore Ching-Kong Cheung, Breda Cullen, Anna Rita Egbert, Jonathan Evans, Maite Garolera, Natalia Gawron, Hetta Gouse, Karolina Hansen, Paweł Holas, Sylwia Hyniewska, Ewa Malinowska, Bernice A. Marcopulos, Tricia L. Merkley, Jose A. Muñoz-Moreno, Clare Ramsden, Christian Salas, Sietske A.M. Sikkes, Ana Rita Silva, Imane Zouhar, the NeuroCOVID International Neuropsychology Taskforce
Journal: Journal of the International Neuropsychological Society / Volume 28 / Issue 6 / July 2022
Published online by Cambridge University Press: 09 August 2021, pp. 642-660
To propose a set of internationally harmonized procedures and methods for assessing neurocognitive functions, smell, taste, mental, and psychosocial health, and other factors in adults formally diagnosed with COVID-19 (confirmed as SARS-CoV-2 + WHO definition).
We formed an international and cross-disciplinary NeuroCOVID Neuropsychology Taskforce in April 2020. Seven criteria were used to guide the selection of the recommendations' methods and procedures: (i) Relevance to all COVID-19 illness stages and longitudinal study design; (ii) Standard, cross-culturally valid or widely available instruments; (iii) Coverage of both direct and indirect causes of COVID-19-associated neurological and psychiatric symptoms; (iv) Control of factors specifically pertinent to COVID-19 that may affect neuropsychological performance; (v) Flexibility of administration (telehealth, computerized, remote/online, face to face); (vi) Harmonization for facilitating international research; (vii) Ease of translation to clinical practice.
The three proposed levels of harmonization include a screening strategy with telehealth option, a medium-size computerized assessment with an online/remote option, and a comprehensive evaluation with flexible administration. The context in which each harmonization level might be used is described. Issues of assessment timelines, guidance for home/remote assessment to support data fidelity and telehealth considerations, cross-cultural adequacy, norms, and impairment definitions are also described.
The proposed recommendations provide rationale and methodological guidance for neuropsychological research studies and clinical assessment in adults with COVID-19. We expect that the use of the recommendations will facilitate data harmonization and global research. Research implementing the recommendations will be crucial to determine their acceptability, usability, and validity.
Effect of thermochemical treatments on the surface hardening of a circular saw blade: A microstructure comparison of nitride layers, boride layers and TiN coating formed on ASTM A1011 steel
Irving Morgado-González, Martín Ortiz-Domínguez, Oscar Gómez-Vargas, Edgar Cardoso-Legorreta, Jesús García-Serrano, Mariana Bárcenas-Castañeda, Víctor Castellanos-Escamilla, Gina Moreno-González, José Solís-Romero
In vitro anti-Acanthamoeba activity of flavonoid glycosides isolated from Delphinium gracile, D. staphisagria, Consolida oliveriana and Aconitum napellus
Rubén Martín-Escolano, Sonia Molero Romero, Jesus G. Díaz, Clotilde Marín, Manuel Sánchez-Moreno, Mª José Rosales
Journal: Parasitology / Volume 148 / Issue 11 / September 2021
Published online by Cambridge University Press: 24 June 2021, pp. 1392-1400
Acanthamoeba spp. are widely distributed in the environment and cause serious infections in humans. Treatment of Acanthamoeba infections is very challenging and not always effective which requires the development of more efficient drugs against Acanthamoeba spp. The purpose of the present study was to test medicinal plants that may be useful in the treatment of Acanthamoeba spp. Here we evaluated the trophozoital and cysticidal activity of 13 flavonoid glycosides isolated from Delphinium gracile, D. staphisagria, Consolida oliveriana and from Aconitum napellus subsp. Lusitanicum against the amoeba Acanthamoeba castellanii. AlamarBlue Assay Reagent® was used to determine the activity against trophozoites of A. castellanii, and cytotoxic using Vero cells. Cysticidal activity was assessed on treated cysts by light microscopy using a Neubauer chamber to quantify cysts and trophozoites. Flavonoids 1, 2, 3 and 4 showed higher trophozoital activity and selectivity indexes than the reference drug chlorhexidine digluconate. In addition, flavonoid 2 showed 100% cysticidal activity at a concentration of 50 μm, lower than those of the reference drug and flavonoid 3 (100 μm). These results suggest that flavonoids 2 and 3 might be used for the development of novel therapeutic approaches against Acanthamoeba infections after satisfactory in vivo evaluations.
Postlaunch evidence-generation studies for medical devices in Spain: the RedETS approach to integrate real-world evidence into decision making
Pedro Serrano-Aguilar, Iñaki Gutierrez-Ibarluzea, Pilar Díaz, Iñaki Imaz-Iglesia, Jesús González-Enríquez, José Luis Castro, Mireia Espallargues, Sandra García-Armesto, Paloma Arriola-Bolado, Amado Rivero-Santana, Lilisbeth Perestelo-Pérez, Himar González-Pacheco, Yolanda Álvarez-Pérez, María José Faraldo-Vallés, Janet Puñal-Riobóo, Yolanda Ramallo-Fariña, Luis María Sánchez-Gómez, José Asua-Batarrita, Eva Reviriego-Rodrigo, Anai Moreno-Rodríguez, Celia Juárez-Rojo, Marisa Vicente-Saiz, Eugenia Orejas-Pérez, Jutta Knabe-Guerra, Isabel Prieto-Yerro, Cristina González del Yerro-Valdés
Journal: International Journal of Technology Assessment in Health Care / Volume 37 / Issue 1 / 2021
Published online by Cambridge University Press: 04 May 2021, e63
The Monitoring Studies (MS) program, the approach developed by RedETS to generate postlaunch real-world evidence (RWE), is intended to complement and enhance the conventional health technology assessment process to support health policy decision making in Spain, besides informing other interested stakeholders, including clinicians and patients. The MS program is focused on specific uncertainties about the real effect, safety, costs, and routine use of new and insufficiently assessed relevant medical devices carefully selected to ensure the value of the additional research needed, by means of structured, controlled, participative, and transparent procedures. However, despite a clear political commitment and economic support from national and regional health authorities, several difficulties were identified along the development and implementation of the first wave of MS, delaying its execution and final reporting. Resolution of these difficulties at the regional and national levels and a greater collaborative impulse in the European Union, given the availability of an appropriate methodological framework already provided by EUnetHTA, might provide a faster and more efficient comparative RWE of improved quality and reliability at the national and international levels.
Prevalence and risk factors of psychiatric symptoms and diagnoses before and during the COVID-19 pandemic: findings from the ELSA-Brasil COVID-19 mental health cohort
André Russowsky Brunoni, Paulo Jeng Chian Suen, Pedro Starzynski Bacchi, Lais Boralli Razza, Izio Klein, Leonardo Afonso dos Santos, Itamar de Souza Santos, Leandro da Costa Lane Valiengo, José Gallucci-Neto, Marina Lopes Moreno, Bianca Silva Pinto, Larissa de Cássia Silva Félix, Juliana Pereira de Sousa, Maria Carmen Viana, Pamela Marques Forte, Marcia Cristina de Altisent Oliveira Cardoso, Marcio Sommer Bittencourt, Rebeca Pelosof, Luciana Lima de Siqueira, Daniel Fatori, Helena Bellini, Priscila Vilela Silveira Bueno, Ives Cavalcante Passos, Maria Angelica Nunes, Giovanni Abrahão Salum, Sarah Bauermeister, Jordan W. Smoller, Paulo Andrade Lotufo, Isabela Martins Benseñor
Journal: Psychological Medicine , First View
There is mixed evidence on increasing rates of psychiatric disorders and symptoms during the coronavirus disease 2019 (COVID-19) pandemic in 2020. We evaluated pandemic-related psychopathology and psychiatry diagnoses and their determinants in the Brazilian Longitudinal Study of Health (ELSA-Brasil) São Paulo Research Center.
Between pre-pandemic ELSA-Brasil assessments in 2008–2010 (wave-1), 2012–2014 (wave-2), 2016–2018 (wave-3) and three pandemic assessments in 2020 (COVID-19 waves in May–July, July–September, and October–December), rates of common psychiatric symptoms, and depressive, anxiety, and common mental disorders (CMDs) were compared using the Clinical Interview Scheduled-Revised (CIS-R) and the Depression Anxiety Stress Scale-21 (DASS-21). Multivariable generalized linear models, adjusted by age, gender, educational level, and ethnicity identified variables associated with an elevated risk for mental disorders.
In 2117 participants (mean age 62.3 years, 58.2% females), rates of CMDs and depressive disorders did not significantly change over time, oscillating from 23.5% to 21.1%, and 3.3% to 2.8%, respectively; whereas rate of anxiety disorders significantly decreased (2008–2010: 13.8%; 2016–2018: 9.8%; 2020: 8%). There was a decrease along three wave-COVID assessments for depression [β = −0.37, 99.5% confidence interval (CI) −0.50 to −0.23], anxiety (β = −0.37, 99.5% CI −0.48 to −0.26), and stress (β = −0.48, 99.5% CI −0.64 to −0.33) symptoms (all ps < 0.001). Younger age, female sex, lower educational level, non-white ethnicity, and previous psychiatric disorders were associated with increased odds for psychiatric disorders, whereas self-evaluated good health and good quality of relationships with decreased risk.
No consistent evidence of pandemic-related worsening psychopathology in our cohort was found. Indeed, psychiatric symptoms slightly decreased along 2020. Risk factors representing socioeconomic disadvantages were associated with increased odds of psychiatric disorders.
Efficacy of an integrative approach for bipolar disorder: preliminary results from a randomized controlled trial
Èlia Valls, C. Mar Bonnín, Imma Torres, Mercè Brat, Mireia Prime-Tous, Ivette Morilla, Xavier Segú, Brisa Solé, Carla Torrent, Eduard Vieta, Anabel Martínez-Arán, María Reinares, José Sánchez-Moreno
Journal: Psychological Medicine / Volume 52 / Issue 16 / December 2022
Published online by Cambridge University Press: 16 April 2021, pp. 4094-4105
Bipolar disorder (BD) represents one of the most therapeutically complex psychiatric disorders. The development of a feasible comprehensive psychological approach to complement pharmacotherapy to improve its clinical management is required. The main objective of the present randomized controlled trial (RCT) was to test the efficacy of a novel adjunctive treatment entitled integrative approach in patients with BD, including: psychoeducation, mindfulness training, and functional remediation.
This is a parallel two-armed, rater-blind RCT of an integrative approach plus treatment as usual (TAU), v. TAU alone. Participants were recruited at the Hospital Clinic of Barcelona and randomized to one of the two conditions. They were assessed at baseline and after finishing the intervention. The main outcome variable included changes in psychosocial functioning assessed through the Functioning Assessment Short Test (FAST).
After finishing the treatment, the repeated-measures analyses revealed a significant group × time interaction in favor of the patients who received the integrative approach (n = 28) compared to the TAU group (n = 37) (Pillai's trace = 0.10; F(1,57) = 6.9; p = 0.01), improving the functional outcome. Significant effects were also found in two out of the six domains of the FAST, including the cognitive domain (Pillai's trace = 0.25; F(1,57) = 19.1; p < 0.001) and leisure time (Pillai's trace = 0.11; F(1,57) = 7.15; p = 0.01). Regarding the secondary outcomes, a significant group × time interaction in Hamilton Depression Rating Scale changes was detected (Pillai's trace = 0.08; F(1,62) = 5.6; p = 0.02).
This preliminary study suggests that the integrative approach represents a promising cost-effective therapy to improve psychosocial functioning and residual depressive symptoms in patients suffering from BD.
Gambling activity in the old-age general population
Amparo del Pino-Gutiérrez, Roser Granero, Fernando Fernández-Aranda, Teresa Mena-Moreno, Gemma Mestre-Bach, Mónica Gómez-Peña, Laura Moragas, Neus Aymamí, Isabelle Giroux, Marie Grall-Bronnec, Anne Sauvaget, Ester Codina, Cristina Vintró-Alcaraz, María Lozano-Madrid, Zaida Agüera, Jéssica Sánchez-González, Gemma Casalé, Isabel Baenas, Isabel Sánchez, Hibai López-González, José M. Menchón, Susana Jiménez-Murcia
Journal: Ageing & Society / Volume 42 / Issue 12 / December 2022
Published online by Cambridge University Press: 23 March 2021, pp. 2757-2783
Old age constitutes a vulnerable stage for developing gambling-related problems. The aims of the study were to identify patterns of gambling habits in elderly participants from the general population, and to assess socio-demographic and clinical variables related to the severity of the gambling behaviours. The sample included N = 361 participants aged in the 50–90 years range. A broad assessment included socio-demographic variables, gambling profile and psychopathological state. The percentage of participants who reported an absence of gambling activities was 35.5 per cent, while 46.0 per cent reported only non-strategic gambling, 2.2 per cent only strategic gambling and 16.3 per cent both non-strategic plus strategic gambling. Gambling form with highest prevalence was lotteries (60.4%), followed by pools (13.9%) and bingo (11.9%). The prevalence of gambling disorder was 1.4 per cent, and 8.0 per cent of participants were at a problematic gambling level. Onset of gambling activities was younger for men, and male participants also reached a higher mean for the bets per gambling-episode and the number of total gambling activities. Risk factors for gambling severity in the sample were not being born in Spain and a higher number of cumulative lifetime life events, and gambling severity was associated with a higher prevalence of tobacco and alcohol abuse and with worse psychopathological state. Results are particularly useful for the development of reliable screening tools and for the design of effective prevention programmes.
9 - Money, Money, Money
By Mauricio Cervantes, Jose F. Moreno
Edited by Alvaro Cuervo-Cazurra, Northeastern University, Boston, Miguel A. Montoya
Book: Innovating for the Middle of the Pyramid in Emerging Countries
Print publication: 04 March 2021, pp 260-292
One of the major problems in the world nowadays is the lack of access to financing for the lower classes, and in developing countries this issue also affects a big part of the middle class. In this chapter, we will analyze innovations that have been implemented in Latin America to help solve the problem of lack of financing in the population of scarce resources, and the companies or organizations behind these innovations. We study companies that are innovative not only in their business model, their group lending work, but also in their social commitment and their integral way of attacking the problem with education and other elements. Additionally, technology has played an important role in the innovation of microfinance institution mainly for the MOP. This chapter analyzes some of the most recent and innovative strategies that microfinancial organizations, dedicated mainly to the MOP population, have created to increase access to their services, and therefore, to improve the financial inclusion of this segment of the population.


Note: Each of the side effects above was reported in 60% or greater of patients treated with peginterferon alfa-2b. Not all possible side effects are included above.
Changes in the tissue of the heart, including risk of heart attack and/or abnormal heart beat. Some changes may happen that can cause your heart to have less ability to pump blood.
Severe changes in your liver function, which can be life-threatening, especially if you have cirrhosis of the liver.
There are no known interactions of peginterferon alfa-2b with food.
Check with your doctor or pharmacist about all other prescription medicines and over-the-counter medicines and dietary supplements (vitamins, minerals, herbs and others) you are taking before starting this medicine as there are known drug interactions with peginterferon alfa-2b. Also, check with your doctor or pharmacist before starting any new prescription or over-the-counter medicines, or dietary supplements to make sure that there are no interactions.


text:
FSLB
History of Basketball in Liberia
Enter Coach Player
View Coach Player
Fundraiser-2020
2020 Basketball Events
FSLB Library (Login)
What do you think about FSLB?
Click on the survey button below to tell us.
Fill Out Survey
DR. MELVIN HALL
A GENTLEMAN, ATHLETE, & SCHOLAR
A PEEP INTO THE PAGES OF HISTORY: THE EXEMPLIFIED EXTRAORDINARINESS OF A BASKETBALL STAR
by Archie Williams
The game of BASKETBALL is undoubtedly one of the world's greatest sports which commands a very huge following worldwide with thousands of legendary players. In Liberia, it is second only to soccer (football).
Back in the days the YMCA Gymnasium on Crown Hill, including the Sports Commission on Broad Street, and the American Cooperative School (ACS) on the Old Road were hotspot arenas where ardent spectators usually congregated to witness eye feasting spectacles of competitive games amongst several clubs, and high schools in and around Monrovia.
Additionally, the RICKS' OLYMPICS also provided a launchpad where the WHO'S WHO amongst several high schools, including the host Ricks; Lott Carey, St. Patricks, CWA; Cathedral, A. M. E. Zion, B. W. Harris, A. G. M.;
M.C., and Wells Hairston participated in various competitive sporting activities with basketball as the main center of attraction.
Additionally, the RICKS' OLYMPICS also provided a launchpad where the WHO'S WHO amongst several high schools, including the host Ricks; Lott Carey, St. Patricks, CWA; Cathedral, A. M. E. Zion, B. W. Harris, A. G. M.; M.C., and Wells Hairston participated in various competitive sporting activities with basketball as the main center of attraction.
At clubs level, Mighty Barrolle; Invincible Eleven, Great Ball Players, United Lakers, Monrovia Pistons, Hedonist, Island Lords, Trojans, Uhuru Kings; Cat Trotters, Nets, Pythons, Hornets, and Oilers amongst others were always in a hot contention for the Liberia Basketball Federation (LBF) annual shield at the Sports Commission.
Per the aforementioned, one individual who amongst several others was a classic standout within the realms of the game is none other than MELVIN HALL. He was an all round player endowed with coveted abilities that enabled him to always perform at his utmost expectations on teams he featured; including Ricks his high school; Cuttington his college, and Mighty Barrolle, his club.
From humble beginnings on Carey Street, Melvin is a 1980 graduate of the Ricks Institute in Virginia outside Monrovia. He obtained a BSc Degree in Chemistry with honors from the Cuttington University in 1984. In furtherance of higher education, he obtained a MSc in Geology from the University of California (Berkeley) in 1989, and a PhD in Organic Chemistry from the Auburn University in 2001.
Shortly after he obtained his MSc. Degree, he returned home in early 1990 amid the sprouts of the war, and was employed with the University of Liberia where he taught Geology, and Chemistry. He rose to the rank of Assistant Professor prior to his departure for terminal studies in 1994. He also coached the University's basketball team.
Moreover, he also taught chemistry and Geography at the St. Teresa Convent High School.
His elder brother Ceaser Hall also a Geologist of the Lands, Mines and Energy Ministry fame was equally an ardent star player for Mighty Barrolle who subsequently became one of the Liberia Basketball Federation (LBF) ace umpires with discipline as his achievable hallmark.
Currently, Dr. Melvin Hall is a Professor of Organic Chemistry at Lagrange College in Georgia the USA.
To view pictures of Dr. Hall when he played for his high school, national club, and the Lone Star of Liberia, click on the button below.
Friends and Supporters of Liberian Basketball, Inc.
Providence, RI. 02905
For general inquiries: email officer@fslb.org
For membership inquiries: email officer@fslb.org
The National Basketball Association
Sports Power
© 2016 Friends and Supporters of Liberian Basketball, Inc. All rights reserved.

redpajama_set_name: RedPajamaCommonCrawl


text:
'The Big Bang Theory' finale: The end of an era in TV programming?
Los Angeles Times 5/16/2019 By Yvonne Villarreal, Los Angeles Times
© Billy Bennight/Zuma Press/TNS Steve Holland, left, and Steve Molaro attend The Big Bang Theory's Series Finale Party at the The Langham Huntington in Pasadena, Calif., on May 1, 2019.
It doesn't take a rocket scientist - or geeky physicists, for that matter - to realize that the conclusion of "The Big Bang Theory," the most-watched comedy on television and a centerpiece of one of TV's most profitable nights, is a blow to CBS. The network had been bolstered by the prime-time powerhouse for the better part of a decade.
But the end of the series, which was to wrap its 12-season run Thursday, has raised another question: Is "The Big Bang Theory" the last of its kind? A relic of a departed era of television when a mainstream sitcom could command a massive audience?
While the Twitterverse has been in full theatrics over HBO's fantasy blockbuster "Game of Thrones" as it too nears its end, it's easy to overlook the significance of its more modest associate on broadcast television.
The comedy, which became TV's longest-running multi-camera sitcom this season, has anchored Thursday nights since 2010 - consistently helping CBS maintain its standing as the most-watched network. While its ratings have receded in recent years, the show still commands an enviable audience. This season, it averaged 12.75 million total viewers (a number that rises to nearly 18 million when delayed viewing over a week is factored in), according to Nielsen - and it's expected to wrap its run near the top of the ratings.
That's a notable run against the backdrop of declining ratings, shifting viewing habits and a saturation of content as the streaming era settles into place.
"It's bittersweet," said Kelly Kahl, the president of CBS Entertainment, who was the head of scheduling when "The Big Bang Theory" launched. "We're heading to a conclusion of a landscape-altering show; a show that means a lot. I think it's more than a CBS thing. It's a network television thing. It was a monster hit for network television - for television in general ... you take it for granted that the audience will be there for you week after week."
The series was co-created by Chuck Lorre and Bill Prady and revolves around a group of geeky physicists and their friendship with an across-the-hall neighbor (and more friends who were added through the years). The high-caliber cast is headed by Jim Parsons, Johnny Galecki, Kaley Cuoco, Simon Helberg, Kunal Nayyar, Mayim Bialik and Melissa Rauch.
There's little debate that achieving such a caliber of success is harder in the current TV boom, but declaring the extinction of a smash broadcast comedy is a dubious distinction that has plagued the genre since the likes of "Friends" and "Everybody Loves Raymond" went off the air. While it's become increasingly difficult for networks to create shows with massive live viewership, there are occasions when things pop (i.e. the blockbuster ratings for the opening episode of last year's revival of "Roseanne").
"It will be difficult for any show to be as popular - in sheer numbers - as 'Big Bang' was ... or as 'Friends' was or 'Seinfeld' was or 'Cheers' was," said Tom Nunan, former president of NBC Studios and UPN and now a lecturer at the UCLA School of Theater, Film and Television. "Those numbers, because of the lack of choices in entertainment at the time, are hard to match anymore, because of the variety of distribution platforms and the competition people have for various forms of entertainment."
The reliable success of "Big Bang" made it a key profit-maker for CBS and Warner Bros., the studio that produces the series. On its own, the show brought in $125 million to $150 million in ad revenue per season for CBS.
And its syndication revenue has reportedly generated more than $1 billion for Warner Bros. Television. With close to 300 episodes in its library, "Big Bang" will likely continue to be a major source of revenue for the studio after its finale - particularly if the show hits the streaming video market. (No decision has been made about whether it will be a part of WarnerMedia's upcoming video streaming service).
"Big Bang" is also one of TV's most expensive shows, with a production price tag that has escalated through the years with producer fees and cast salaries. The five main actors who have been with the series since its early days - Parsons, Galecki, Cuoco, Nayyar and Helberg - make just under $1 million an episode.
The network and the studio considered the show so important that there were talks to try to extend it. The decision to wrap things up came after Parsons, who has won four Emmys for his role, was ready to leave and pursue other projects.
"I just couldn't imagine doing this show if any of the principals were not there," Lorre said. "It just wouldn't feel right."
Or, as Prady tells it: "There's something truly wonderful about stopping at a point where you are still loved... no one wants to be Babe Ruth playing for Cleveland at the end, you know? You want to finish it as Babe Ruth playing for the Yankees."
Steve Holland, a longtime "Big Bang" executive producer and writer who became showrunner last season after Steve Molaro left to head up the spinoff "Young Sheldon," gathered to map out the finale with Molaro and Lorre once things became official. The final shot of the series, though, "had been on their minds for at least a decade," Holland said.
"You can second-guess yourself to death," said Holland, who will join "Young Sheldon" as an executive producer next season. "And in a good way, we have deadlines. You can't just sit back and second-guess forever."
That's a sentiment Lorre knows all too well. The veteran producer, whose other current credits include "Mom" and "The Kominsky Method," has said goodbye to shows before. Still, he said, it's tough.
"It's the disbursal of a family," is how he describes it. "I've been part of this for a long, long time. Babies have been born, there's been weddings and divorces - and everything imaginable that happens to a group of people over 12 years. And it becomes part of the fabric of your life. Then, for it to end ... it's a little bit unfathomable.
"I think I'm in denial. It's hard to wrap my head around the idea this is coming to an end. So I don't dwell on it."
For Molaro, who was able to help shape the final episode because "Young Sheldon" had wrapped production, working on the show's prequel makes the "Big Bang" ending slightly less jarring.
"I don't want to get my movies wrong, but I believe it's in 'Turner & Hooch' where, at the end, the dog dies but then you realize it had puppies and that's some consolation prize. So, in that way, I do have a puppy. A 'Big Bang' puppy."
FINAL TAPING
On the final Tuesday of April, inside Stage 25 on the Warner Bros. lot in Burbank, reality is setting in just outside the bounds of Apartment 4A as the show's final episode is taped.
One by one, just as in every taping, the members of the cast are introduced to enthusiastic applause from the studio audience. There are smiles, sure. But eyes are welled up with tears too. Cuoco's. Bialik's. Galecki's - enough to prompt one of the show's makeup artists to do some touch-ups. As they scatter about before the cameras start to roll, there are hugs and selfies and a soundtrack from the audience, which shouts in unison: "We love 'The Big Bang Theory'!"
Family and friends of the cast were in attendance, including Parson's mother and Cuoco's father - the latter has attended every Tuesday taping of the series.
"When I watched the pilot, I told my daughter that I'd be at every taping - I never imagined it would go on this long," said Gary Cuoco, fighting back tears. "It's been a beautiful experience. So there's happiness and sadness. My Tuesdays won't be the same."
The finality of it all lingered on the set. During one break from taping, Kaley Cuoco and Galecki climbed the audience barrier and addressed the crowd while fighting back tears: "Would you please allow us to thank you for a moment," Galecki exclaimed. "You've been the best fans for 12 years."
Ahead of the final scene taped in front of the audience (but not the episode's final scene), an emotional Lorre banged the clapboard and yelled, "Action!" When the final curtain call came, Green Day's "Good Riddance (Time of Your Life)" played over the speakers.
"It's crazy how connected you can get to characters," longtime viewer Brian Pereyra, a 29-year-old IT worker from Gainesville, Fla., said after the taping. "This is an amazing experience. Being a fan of the show, I never, ever wanted to see it end. I know people say things have to end some time. I'm of the mind-set that it can go on forever. But that may be selfish on my part. Personally, I thought it was a very satisfying ending."
A day after filming the series finale, cast members added their handprints to the mix outside the TCL Chinese Theatre in Hollywood. And CBS has scheduled a 30-minute retrospective that will follow the season finale of "Big Bang" prequel "Young Sheldon."
For what it's worth, those involved with the show aren't convinced its conclusion signals that a certain kind of TV hit is necessarily a thing of the past. There's hope that "Young Sheldon" will continue to grow - it currently averages 11 million total viewers; a number that climbs to 14.62 million over seven days, according to Nielsen figures. And CBS announced Wednesday that the comedy will take over the "Big Bang" time slot next fall.
"It would be foolish of me to say, 'No, it will never happen again' - I've learned too many times over the years to never make declarative statements about what can or can't be" said Peter Roth, president and chief content officer of Warner Bros. Television.
Because, as Lorre said, one can never predict these things.
"The audience is fragmented, maybe because of the thousands of choices," he said. "But for all you and I know, somebody's sitting alone in their room miserable right now writing a script that's gonna land with the right group of actors and it'll explode into the culture. I think it would be presumptuous to assume it won't or can't happen again. The scale might be different, because of the media landscape, but the impact could be the same or probably greater."
Like a big bang.
Visit the Los Angeles Times at www.latimes.com
© 2019 Microsoft Privacy & Cookies Terms of use About our Ads Feedback Help MSN Worldwide Newsletter MSN TV MSN Blog About Us


text:
package org.commonjava.indy.repo.proxy.ftest;

import org.apache.commons.io.IOUtils;
import org.commonjava.indy.ftest.core.AbstractContentManagementTest;
import org.commonjava.indy.model.core.HostedRepository;
import org.commonjava.indy.model.core.RemoteRepository;
import org.commonjava.indy.test.fixture.core.CoreServerFixture;
import org.junit.Before;
import org.junit.Test;

import java.io.ByteArrayInputStream;
import java.io.IOException;
import java.io.InputStream;

import static org.commonjava.indy.pkg.PackageTypeConstants.PKG_TYPE_NPM;
import static org.commonjava.maven.galley.util.PathUtils.normalize;
import static org.hamcrest.CoreMatchers.containsString;
import static org.hamcrest.CoreMatchers.equalTo;
import static org.hamcrest.CoreMatchers.notNullValue;
import static org.hamcrest.MatcherAssert.assertThat;

/**
 * Check if the NPM metadata rewriting features can be disabled when addon can work itself
 *

 * GIVEN:
 *

 *
Hosted and Remote NPM Repo

 *
Path for NPM metadata

 *
Hosted does not have path but Remote does

 *
Configured proxy rule with mapping hosted proxy to remote

 *
Configured the "npm.meta.rewrite.enabled" to disabled

 *

 *

 * WHEN:
 *

 *
Request path through hosted

 *

 *

 * THEN:
 *

 *
The content of path can be returned correctly from hosted

 *
The url in the content which points to Remote for the returned path has not been rewritten to point to Hosted

 *

 */
public class RepoProxyNPMMetaRewriteDisableTest
        extends AbstractContentManagementTest
{
    private static final String REPO_NAME = "npmjs";

    private HostedRepository hosted;

    private RemoteRepository remote;

    private static final String PATH_ROOT = "jquery";

    private static final String PATH_SCOPED = "@angular/core";

    private static final String PATH_PACKAGE_JSON = "jquery/package.json";

    //@formatter:off
    private static final String CONTENT_JQUERY_TEMPLATE = "{"
            + "\"_id\": \"jquery\","
            + "\"versions\":{"
            + "\"1.5.1\": {"
            + "\"dist\": {"
            + "\"shasum\": \"2ae2d661e906c1a01e044a71bb5b2743942183e5\","
            + "\"tarball\": \"%s/jquery/-/jquery-1.5.1.tgz\""
            + "}"
            + "}"
            + "}"
            + "}";

    private static final String CONTENT_ANGULAR_CORE_TEMPLATE = "{"
            + "\"_id\": \"@angular/core\","
            + "\"versions\": {"
            + "\"9.0.1\": {"
            + "\"dist\": {"
            + "\"shasum\": \"8908112ce6bb22aa1ae537230240ef9a324409ad\","
            + "\"tarball\": \"%s/@angular/core/-/core-9.0.1.tgz\""
            + "}"
            + "}"
            + "}"
            + "}";
    //@formatter:on

    private String CONTENT_JQUERY;

    private String CONTENT_ANGULAR_CORE;

    private String REMOTE_REPO_PATH;

    private String HOSTED_REPO_PATH;

    @Before
    public void setupRepos()
            throws Exception
    {
        CONTENT_JQUERY = String.format( CONTENT_JQUERY_TEMPLATE, server.formatUrl( REPO_NAME ) );
        server.expect( server.formatUrl( REPO_NAME, PATH_ROOT ), 200,
                       new ByteArrayInputStream( CONTENT_JQUERY.getBytes() ) );
        server.expect( server.formatUrl( REPO_NAME, PATH_PACKAGE_JSON ), 200,
                       new ByteArrayInputStream( CONTENT_JQUERY.getBytes() ) );

        CONTENT_ANGULAR_CORE = String.format( CONTENT_ANGULAR_CORE_TEMPLATE, server.formatUrl( REPO_NAME ) );
        server.expect( server.formatUrl( REPO_NAME, PATH_SCOPED ), 200,
                       new ByteArrayInputStream( CONTENT_ANGULAR_CORE.getBytes() ) );

        remote = client.stores()
                       .create( new RemoteRepository( PKG_TYPE_NPM, REPO_NAME, server.formatUrl( REPO_NAME ) ),
                                "remote npmjs", RemoteRepository.class );

        hosted = client.stores()
                       .create( new HostedRepository( PKG_TYPE_NPM, REPO_NAME ), "hosted npmjs",
                                HostedRepository.class );

        REMOTE_REPO_PATH = normalize( fixture.getUrl(), "content/npm/remote", remote.getName() );
        HOSTED_REPO_PATH = normalize( fixture.getUrl(), "content/npm/hosted", hosted.getName() );

    }

    @Test
    public void run()
            throws Exception
    {
        try (InputStream result = client.content().get( hosted.getKey(), PATH_ROOT ))
        {
            assertThat( result, notNullValue() );
            final String content = IOUtils.toString( result );
            logger.debug( "NPM Rewrite content: {}", content );
            assertThat( content, containsString( REMOTE_REPO_PATH ) );
            assertThat( content.contains( HOSTED_REPO_PATH ), equalTo( false ) );
        }

        try (InputStream result = client.content().get( hosted.getKey(), PATH_SCOPED ))
        {
            assertThat( result, notNullValue() );
            final String content = IOUtils.toString( result );
            logger.debug( "NPM Rewrite content: {}", content );
            assertThat( content, containsString( REMOTE_REPO_PATH ) );
            assertThat( content.contains( HOSTED_REPO_PATH ), equalTo( false ) );
        }

        try (InputStream result = client.content().get( hosted.getKey(), PATH_PACKAGE_JSON ))
        {
            assertThat( result, notNullValue() );
            final String content = IOUtils.toString( result );
            logger.debug( "NPM Rewrite content: {}", content );
            assertThat( content, containsString( REMOTE_REPO_PATH ) );
            assertThat( content.contains( HOSTED_REPO_PATH ), equalTo( false ) );
        }
    }

    @Override
    protected void initTestConfig( CoreServerFixture fixture )
            throws IOException
    {
        writeConfigFile( "conf.d/repo-proxy.conf", "[repo-proxy]\nenabled=true\nnpm.meta.rewrite.enabled=false" );
    }

}

redpajama_set_name: RedPajamaGithub


text:
We'd love to get patches from you!

## Building dependencies

We are not currently publishing snapshots for Finagle's dependencies, which
means that it may be necessary to publish the `develop` branches of these
libraries locally in order to work on Finagle's `develop` branch. To do this you
should clone [Util][util] and [Ostrich][ostrich], check out their `develop`
branches, and run `./sbt +publishLocal` for each project.

We are planning to begin publishing snapshots soon, which will make these steps
unnecessary. If you have any questions or run into any problems, please create
an issue here, tweet at us at [@finagle](https://twitter.com/finagle), or email
the Finaglers mailing list.

## Workflow

The workflow that we support:

1.  Fork finagle
2.  Check out the `develop` branch
3.  Make a feature branch (use `git checkout -b "cool-new-feature"`)
4.  Make your cool new feature or bugfix on your branch
5.  Write a test for your change
6.  From your branch, make a pull request against `twitter/finagle/develop`
7.  Work with repo maintainers to get your change reviewed
8.  Wait for your change to be pulled into `twitter/finagle/develop`
9.  Merge `twitter/finagle/develop` into your origin `develop`
10.  Delete your feature branch

## Testing

We've standardized on using the [ScalaTest testing framework][scalatest].
Because ScalaTest has such a big surface area, we use a restricted subset of it
in our tests to keep them easy to read.  We've chosen the `assert` API, not the
`Matchers` one, and we use the [`FunSuite` mixin][funsuite], which supports
xUnit-like semantics.

We encourage our contributors to ensure Java compatibility for any new public APIs
they introduce. The easiest way to do so is to provide _Java compilation tests_
and make sure the new API is easily accessible (typing `X$.MODULE$` is not easy)
from Java. These compilation tests also provide Java users with testable examples
of the API usage. For an example of a Java compilation test see
[AddrCompilationTest.java][9].

Note that while you will see a [Travis CI][travis-ci] status message in your
pull request, this may not always be accurate, and in any case all changes will
be tested internally at Twitter before being merged. We're working to make
Travis CI more useful for development, but for now you don't need to worry if
it's failing (assuming that you are able to build and test your changes
locally).

## Style

We generally follow [Effective Scala][es] and the [Scala Style Guide][ssg]. When
in doubt, look around the codebase and see how it's done elsewhere.

Comments should be formatted to a width no greater than 80 columns.

Files should be exempt of trailing spaces.

We adhere to a specific format for commit messages. Please write your commit
messages along these guidelines:
    One line description of your change (less than 72 characters)

    Problem

    Explain here the context, and why you're making that change.
    What is the problem you're trying to solve?

    Solution

    Describe the modifications you've done.

    Result

    After your change, what will change?

## Code Review

The Finagle repository on GitHub is kept in sync with an internal repository at
Twitter. For the most part this process should be transparent to Finagle users,
but it does have some implications for how pull requests are merged into the
codebase.

When you submit a pull request on GitHub, it will be reviewed by the
Finagle community (both inside and outside of Twitter), and once the changes are
approved, your commits will be brought into the internal system for additional
testing. Once the changes are merged internally, they will be pushed back to
GitHub with the next release.

This process means that the pull request will not be merged in the usual way.
Instead a member of the Finagle team will post a message in the pull request
thread when your changes have made their way back to GitHub, and the pull
request will be closed (see [this pull request][0] for an example). The changes
in the pull request will be collapsed into a single commit, but the authorship
metadata will be preserved.

Please let us know if you have any questions about this process!

## Getting Started

We've created [a `Starter` label][1] for issues that we think are likely to be
reasonably limited in scope and ready to be tackled by new contributors. Please
feel free to ask questions in the issue thread or [on the mailing list][2] if
you run into problems trying to implement a new feature or fix a bug described
in one of the starter issues.

## Documentation

We also welcome improvements to the Finagle documentation, which is maintained
in this repository and hosted on [the corresponding GitHub Pages site][3].

Finagle uses [Sphinx][4] to generate its user guide via the built-in Sphinx
support in the [sbt-site plugin][5]. You'll need to [install Sphinx][6] on
your system before you can build the site locally.

Once you've got Sphinx installed, you can make changes to the [RST][7] files in
the `doc/src/sphinx` directory and then build the site with the following
command:

``` bash
./sbt 'project finagle-doc' make-site
```

You can then view the site locally at `doc/target/site/index.html`.

Please note that sbt-site currently will not work with the Python 3 version of
Sphinx. It's also hard-coded to call an executable named `sphinx-build`, which
on some systems may be the name of the Python 3 version, with the Python 2
version named `sphinx-build2`. If the site build process crashes with a "Failed
to build Sphinx html documentation", this is likely to be the problem. The
simplest solution is to create a symbolic link to `sphinx-build2` named
`sphinx-build` somewhere on your path.

Please note that any additions or changes to the API must be thoroughly
described in [ScalaDoc][8] comments. We will also happily consider pull
requests that improve the existing ScalaDocs!

[0]: https://github.com/twitter/finagle/pull/267
[1]: https://github.com/twitter/finagle/issues?direction=desc&labels=Starter&sort=created&state=open
[2]: https://groups.google.com/d/forum/finaglers
[3]: https://twitter.github.io/finagle/
[4]: http://sphinx-doc.org/
[5]: https://github.com/sbt/sbt-site
[6]: http://sphinx-doc.org/install.html
[7]: http://docutils.sourceforge.net/rst.html
[8]: http://docs.scala-lang.org/style/scaladoc.html
[9]: https://github.com/twitter/finagle/blob/master/finagle-core/src/test/java/com/twitter/finagle/AddrCompilationTest.java
[es]: https://twitter.github.io/effectivescala/
[funsuite]: http://www.scalatest.org/getting_started_with_fun_suite
[ostrich]: https://github.com/twitter/ostrich
[scalatest]: http://www.scalatest.org/
[ssg]: http://docs.scala-lang.org/style/scaladoc.html
[travis-ci]: https://travis-ci.org/twitter/finagle
[util]: https://github.com/twitter/util


text:
Five Terrific, Must-Read Kiwi Crime Novels Set in Otago
The biannual Dunedin Writers & Readers Festival is now in full swing, with plenty of terrific events for booklovers to enjoy over this weekend. A big highlight is the Crime Time session with visiting mystery masterminds Ian Rankin, Stella Duffy, and MJ Carter, chaired by local crime queen Vanda Symon, but there's plenty more fantasticness on offer (see full programme here, crime picks here).
Inspired by our own City of Literature bringing some great international crime writers to Otago (and this feature I read today highlighting five classic Auckland-set novels in the lead-up to AWRF), I thought I'd reciprocate by sharing a reading list of superb Otago-set crime tales that can give readers from around the world a page-turning story infused with a real sense of this southern province in New Zealand.
So pull up a couch (don't set it on fire), grab your blue and yellow scarf, and let's dive in.
THE RINGMASTER by Vanda Symon
Given she's chairing the Crime Time panel at the Dunedin Writers & Readers Festival, it seems only appropriate to start with New Zealand's modern day Queen of Crime. A former pharmacist who's recently completed a PhD studying the use of poisons in crime fiction by the likes of Dame Ngaio Marsh in crime fiction, Symon is also a medal-winning competitor in masters-level fencing. So the Dunedin author is doubly deadly in real life, let alone her excellent crime novels.
Symon has written five crime novels so far, including four in her Sam Shephard series. Her books have been shortlisted for the Ngaio Marsh Award for Best Crime Novel three times, translated into German, and praised as "superlative storytelling packed with vivid scenes, touches of humour, and one of the most engaging heroines around".
Symon's 2008 follow-up to her excellent debut Overkill finds heroine Sam Shephard having moved to Dunedin from Mataura; bridges burnt. Undertaking detective training, Sam's on the bottom rung of the ladder. The Ringmaster opens with a murder in the Botanic Gardens, before switching to stroppy Sam's first-person narration. Marginalised, she struggles to participate in the investigation, working in her own time and feeding off the scraps her partner Smithy smuggles her way. She eventually uncovers a link between the visiting circus, and a series of deaths throughout the lower South Island.
One of many great facets of this novel is Symon's use of the Dunedin setting. From the opening murder beside the Leith, to Highlanders games, and student life, Symon brings alive this southern city. When interviewed, Symon has said, "a town will have a feel, a social background. I like using Dunedin. It has a vibrancy and an edge with the students and all that brings with it."
HUNTING BLIND by Paddy Richardson
Symon's fellow Kiwi crime queen Paddy Richardson is also appearing onstage this weekend, tasked with riding shotgun to the infectious energy of Tokoroa-raised novelist, theatremaker, and Fun Palaces champion Stella Duffy (grab your tickets here). Richardson is herself a prolific writer, with two collections of shorts stories and seven novels under her belt. Five of Richardson's seven novels have been top notch psychological thrillers. Her books have been shortlisted for the Ngaio Marsh Award for Best Crime Novel twice, translated into German, and been praised for blending modern thrillers with social commentary and history, creating very New Zealand stories that are "stylishly written and compellingly plotted".
While all of Richardson's psychological thrillers are good to outstanding reads, the one that screams 'Otago' to me the most is Hunting Blind, which was shortlisted for the 2011 Ngaio Marsh Award. The story begins at a lakeside school picnic in Wanaka, Central Otago, back in the late 1980s. Minna Anderson is there with her four children, when tragedy strikes. Her four-year-old daughter Gemma disappears. A massive search fails to turn up any trace, not even a body. The family is torn apart by the tragedy, but the investigation eventually fades. Many years later Gemma's sister Stephanie is completing a psychiatry course in Dunedin, when she's assigned a suicidal and uncommunicative new patient who gradually reveals an eerily similar story. While reluctant to reopen old wounds, Stephanie is compelled to investigate - could the same person be responsible for both abductions?
This is a terrific read, a character study crime novel that's "a gripping and truly human story of what happens when families have to cope with the unthinkable", further elevated by its strong sense of place. As US mystery writer, professor, critic (and now Ngaio Marsh Awards judge) Margot Kinberg said back in her 2011 review for Crime Watch, "As Stephanie searches for Gemma's abductor, she travels to several places on South Island, and each is described in lovely but not overburdening detail. One gets a really authentic sense of life there not just from the physical setting but from several other little touches that really add to the context".
PANCAKE MONEY by Finn Bell
The most recent of my recommendations, just published last year and in the running for this year's Ngaio Marsh Awards (judging is currently going on). Finn Bell is a new addition to the #yeahnoir ranks, with the Dunedin-based full-time author releasing both his debut Dead Lemons, and Pancake Money, on Amazon Kindle in 2016. He has another two crime novels coming out this year.
I first came across a mention of Bell's writing thanks to the well-respected British website, CrimeFictionLover, which gave a big thumbs up to Dead Lemons as part of its 'Ten to Taste' roundup of top self-published novels that could 'blow your mind', last November. A separate, more in-depth review on the same website was equally effusive, calling Bell a talented writer who'd "constructed a compelling and accomplished story that doesn't wallow or stall... this slice of Kiwi noir is very moreish" and that he was a welcome arrival and an author to watch in future.
I was intrigued. And having now read Bell's first two novels, I can see why the overseas critics were raving. While both are very good crime reads from a distinctive new voice, Bell's debut is set in Southland and this second tale is based in Otago, so Pancake Money gets the nod here. Bobby Ress is a Dunedin detective with a family life who just wants to make a difference. But he's thrust into a horrifying case when two Catholic priests are not only murdered, but martyred in torturous, medieval fashion, Ress and his partner Pollo don't know whether they're hunting a vicious serial killer, or a team of vigilantes exacting some sort of revenge. As they dig into the priests' pasts, they have to confront some of the darkest corners of humanity, putting their own lives on the line.
This is clever, dark crime fiction populated with engaging characters, authentic relationships, a strong narrative drive, and powerful threads about philosophy and human psychology. All set against a cinematic evocation of Otago's urban and rural landscapes, which add to the moody atmosphere.
TWISTER by Jane Woodham
If you like deeply character-centric crime, then this recent Kiwi crime novel, which was a finalist in last year's Best First Novel category at the Ngaio Marsh Awards, could be right up your alley.
Woodham, who immigrated to Dunedin from London almost twenty years ago, is a founding member of the Dunedin Detection Club, alongside fellow Ngaio Marsh Award finalists Symon and Richardson, and 2014 Ngaio Marsh Award winner Liam McIlvanney. Before writing Twister, Woodham had twice been a finalist in the prestigious BNZ Katherine Mansfield Short Story Competition, and had her short stories published in New Zealand and the United Kingdom. She certainly knows her way around a great story, and how to craft deep, authentic characters that tug at readers' hearts and minds as the pages turn.
In Twister, Dunedin is suffering from a series of plagues: an unseasonal flu epidemic, cats are getting tortured, and a spate of gay bashings. When a storm tears up the city, the body of a missing schoolgirl is uncovered. It's a particularly tough case for Detective Senior Sergeant Leo Judd, whose own daughter disappeared nine years ago. He and his wife Kate have never really recovered, and unbeknownst to Judd, Kate has been having an affair with their old neighbour, Rea, and intends to leave him. Pressure mounts on the work and home fronts, as Judd tries to overcome his own grief while Kate plucks up the courage to confess not just her affair, but a secret she's been keeping for years.
This is a very fine novel that's as much or more about the impact of crime on the people involved, as solving crime or catching criminals. Woodham crafts an emotional spiderweb of human relationships, with the investigation bubbling along in the background and used to ramp up tension and reveal character. She also does an excellent job evoking a strong sense of Dunedin. As US author and Ngaio Marsh Awards judge Margot Kinberg said, "It's the kind of 'small world' place where people know each other and where gossip spreads ... Woodham shares the diverse cultural makeup of the city. Readers who enjoy a strong sense of place in the novel will appreciate this".
NIGHT VISION by Ella West
West is an Otago freelance journalist, novelist, and playwright who lives on a farm near Mosgiel, a small township just south of Dunedin. Her novels are thrilling tales for young adults. Her debut, Thieves, was shortlisted for the New Zealand Post Book Awards for Children & Young Adults, and spawned an acclaimed trilogy.
While her first three books were thrillers set in a sci-fi world (the second book was also a finalist for the Sir Julius Vogel Awards from New Zealand's Science Fiction & Fantasy Association), West's fourth novel was a crime thriller that drew on her own love for and experiences of rural life. Night Vision, an engaging tale starring an exceptional girl, was published in 2014 and went on to win both the Young Adult Fiction Award at the 2015 LIANZA Children's Book Awards, and the YA Children's Choice Award at the 2015 New Zealand Book Awards for Children and Young Adults.
Young Viola was born with rare genetic condition Xeroderma Pigmentosum, making her at dangerous risk from anything that emits ultraviolet light, including the sun. So she's a 'moon child', and while her parents sleep she explores the family sheep farm and surrounding forest by night, sharing the natural world with the moreporks, possums, and other nocturnal creatures prowling the darkness. One night, she witnesses a vicious crime, and sees the perpetrator bury a sack of money. With her parents in danger of losing their farm, Viola decides to take the money to help her family, drip-feeding it to them over time. While the Police are looking in the wrong direction, Viola finds herself in the criminal's crosshairs after a newspaper interview about her and her condition tips off the local drug dealer as to just who might have taken his money.
Night Vision would be a truly superb mystery for adolescent readers, and could still be greatly enjoyed by older teens and adults. I liked it a lot, even if the young adult-targeted plotline was more straightforward than the adult crime I usually read. Viola is a terrific narrator, a unique and engaging girl who draws us into her perspective on the world. West brings the Otago rural setting to life, on the farm and in the forest. The nocturnal perspective on the local bush, the dual serenity and danger of nature, was well evoked and created an atmospheric backdrop to an intriguing tale.
Craig Sisterson is a lapsed lawyer who writes features for leading magazines and newspapers in several countries. He has interviewed more than 180 crime writers, discussed crime writing onstage at festivals in Europe and Australasia, on national radio, is a judge of the McIlvanney Prize, and is the Judging Convenor of the Ngaio Marsh Awards. You can follow him on Twitter: @craigsisterson
Labels: feature, nz crime


Designed for use with "Convert: From Adam to Christ", this download Study Guide includes discussion questions specifically tailored for individual use or for small groups. It's perfect for Sunday School classes as well.
"I plan on taking the whole church through Convert."
Designed for use with "Convert: From Adam to Christ", this download Study Guide includes discussion questions for every chapter that are specifically tailored for individual use or for small groups. It's perfect for Sunday School classes as well.


text:
Strata 2012 Musings
By Steve Miller
March 06, 2012, 9:11 a.m. EST
I finally got home Sunday evening from my crazy travels of last week. From Chicago to San Francisco and back for Strata 2012, to Winston-Salem NC and back for my daughter's college visit.
Throw in bad connections, weather delays and flight cancellations, and you have the makings for quite the memories. Fortunately, despite the many inconveniences, both trips were very much worthwhile.
Strata Santa Clara 2012, the "leading event for the people and technology driving the data revolution," was an even bigger deal than Santa Clara 2011, which was a significant hit for a 1.0 conference. There were almost 2,500 registrants in 2012 taxing facilities of the convention center compared to 1,400 or so last year. The crowd seemed older this year as well, perhaps reflecting the growing maturity of the discipline. Mainstream vendors such as Oracle, Microsoft and IBM were much more prominent in 2012, serving as event sponsors and major exhibitors. Indeed, when I first experienced the extravagant EMC booth in the exhibit hall, I thought I was in Las Vegas rather than Santa Clara. What a difference a year makes.
Several of the 10-15 minute keynotes on Feb. 29-March 1 were exemplary. Apache Software and Cloudera's Doug Cutting was ever credible as a data science statesman in his presentation on the Hadoop ecosystem. And I was pleasantly surprised with the Hadoop embrace articulated by David Campbell from none other than Microsoft. Avinash Kaushik was most entertaining in his frenetic performance describing the framework of ex-Secretary of Defense and current data science "luminary" Donald Rumsfeld. Kaushik is much less impressed with the data puking of "known-knowns" than he is with the data orgasm-inducing "unknown-unknowns."
Physician/data scientist Ben Goldacre presented a sobering view of scientific medicine, arguing that the "information architecture of medicine is broken." A combination of bad A/B tests (clinical trials), poor synthesis of existing studies, and ineffective communication can torpedo the best intentions of evidence-based medicine. In one meta-analysis, anti-depressant drug study, what appears to be strong supportive evidence (36 + studies, 1 – study) turns out to be non-committal at best (37 + results and 36 – results) when all known studies are summarized.
Finally, Google's Hal Varian, if not the originator of data science, certainly its patron saint, dazzled with analytics and graphics using Google Trends, Google Insights for Search and R. Data science at its best.
The many breakout sessions forced me to make decisions on the themes I wished to pursue. I opted to pretty much avoid the vendor-sponsored presentations and decided also to leave the technical, big data infrastructure sessions to my OpenBI colleagues. My foci were data strategy, visualization and analytics.
Karmasphere founder Martin Hall contrasted data science teams with their traditional BI/DW progenitors, the point of departure differences revolving on relational database versus Hadoop-NoSQL infrastructures. Comfortingly, team roles are conceptually not too dissimilar, with a path from BI's data analysts to DS's data scientists, and from BI's DBAs/ETL programmers to DS's MapReduce-NoSQL coders. Emerging software that bridges BI and DS data might turbo-charge that transition.
Tableau executive, Stanford Ph.D. and visualization notable Jock MacKinlay got the longer presentations off to a great start with his highly-informative "Science of Visualization." Driving from the study of human perception, MacKinlay used simple Tableau illustrations to argue that position, size and color – in that order – are significant determinants of statistical visual quality. He also espoused the use of lattice graphics --"small multiples" – for visualizing dimensional data.
Two of the analytics presentations I caught, while informative, were less data science and more BI/data warehousing. "The Mining of Eventbrite" by Vipul Sharma, in contrast, showed the best of big data management and data science analytics. The work of the Eventbrite team revolves on recommendations for future events, emphasizing social and interest graph-based methods. Vipul's presentation simultaneously illuminated the handling of 15 M customers with 1.1 trillion graph edges in the Hadoop infrastructure and machine learning with logistic regression on a sparse feature set for classification.
The "press conference" linking key presenters to journalists/media was a personal highlight. Discussion revolved on the role of experts versus analytics in evolving data science. The group debated the value of domain experts in calibrating both inputs and outputs of mathematical optimization, as well as the ageless question of correlation versus causality. While most panelists felt expertise was important to framing hypotheses and guiding the scientific method, the thinking was not unanimous. A minority view held that a rigorous methodology in the absence of domain expertise might be optimal. A left-unanswered rhetorical question was what happens when everyone uses big data/analytics – are the benefits of analytics zero-sum?
While Kaggle President Jeremy Howard might question the need for domain expertise to drive data science, he certainly promotes a rigorous methodology and learning framework. For Howard, it's identify objectives, determine what levers can be pulled, find data that links levers to objectives, and evaluate the linkages with algorithms. His is a true scientific framework that deploys randomized experiments to simulate and optimize outcomes. And you've just got to love a data scientist who speaks of using randomized experiments as a proxy for divining "counter-factuals."
I can't wait for Strata 2013 Bay Area. Maybe next year the Moscone Center in San Francisco?
AnalyticsData architectureData visualization Big dataData and information managementBusiness intelligence


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text:
namespace AntShares.Linq
{
    export class DistinctEnumerator<T> extends Enumerator<T>
    {
        private set = new Array<T>();

        constructor(private enumerator: Enumerator<T>, private comparer: Func2<T, T, boolean>)
        {
            super();
        }

        public next(): boolean
        {
            while (this.enumerator.next())
            {
                let flag = false;
                for (let i = 0; i < this.set.length; i++)
                {
                    if (this.comparer(this.enumerator.value(), this.set[i]))
                    {
                        flag = true;
                        break;
                    }
                }
                if (!flag)
                {
                    this.set.push(this.value());
                    return true;
                }
            }
            return false;
        }

        public reset(): void
        {
            this.set.length = 0;
            this.enumerator.reset();
        }

        public value(): T
        {
            return this.enumerator.value();
        }
    }
}


At a particular stage of the season, the promotion battle from the Sky Bet Championship seemed like a very easy task for Newcastle. They were sitting first and winning their games very convincingly. After a series of less-than-ideal results, the team now sits second, but the far more disturbing news for their fans is that their game isn't working. Can Brentford profit from this bad form?
In their direct game on the 16th of January, they will have their home fans on their side as well. It's worth mentioning that they haven't lost their last 3 league home games, although they aren't one of the better teams in the league.
Their current form is better, 8 points from their last 5 games, and this is what they will hope to take them towards the three points on Monday. Even if they lose, the fans won't be extremely disappointed – nobody expects Brentford to produce any fireworks this season.
On the other hand, the Magpies must return to their winning ways soon, or else they will drop from the places which ensure direct promotion into the Premier League. They have lost 2 games in their last 5, against Blackburn and Sheffield, both by the same scoreline: 0-1.
The first game between the two teams took place at St. James Park and finished with a 3-1 score, which Newcastle will want to repeat. If Reading win their game in hand an Newcastle lose against Brentford, they could even drop to 3rd place.
That being said, we favor the away team in this match. Their superior motivation, skill, and squad should be enough to ensure at least a goal or two, if not an outright win. Newcastle to score or X2 are the safe bets of the day, while we wouldn't rule out a solo away win either. Good luck!


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Smoke-free is an asset to the business, because there is more socialization versus trying to run away from the smoke, people can taste the food versus the smoke, and we all feel better in a smoke-free environment.
I feel that smoke is dangerous to people and is poison. Being smoke-free is the right thing to do.
I am from Boulder, and their smoke-free policies have been great for business and health. Let�s lead the state being the best.