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K 01-162
K 01-162 binds and destabilizes A?O (?-amyloid( EC50= 0. 080 mM; IC50= 80 nM), can reduce the brain amyloid burden that exists in both fibrillar and RIPA-soluble, non-fibrillar forms. Synonyms: 7-bromo-N, N-dimethyl-9H-fluoren-2-amine; 9H-Fluoren-2-aMine, 7-broMo-N, N-diMethyl-;. Cas No. 677746-25-7. Molecular formula C15H14BrN. Molecular weight 288.19. Laboratory Chemicals.
K02288 is a highly selective 2-aminopyridinebased inhibitor K02288 with in vitro activity against ALK2 at low nanomolar concentrations similar to the current lead compound LDN-193189. K02288 specifically inhibited the BMP-induced Smad pathway without affe Synonyms: K 02288; K-02288. Cas No. 1431985-92-0. Molecular formula C20H20N2O4. Molecular weight 352.38. Laboratory Reagents.
K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18. 6 nM, 15. 4 nM, and 9. 7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. Cas No. 853299-07-7. Molecular formula C24H26F3N7O2. Molecular weight 501.5. Laboratory Reagents.
K 114 is a potent amyloid fibril-specific fluorescent dye (EC50 = 20-30 nM). Synonyms: 4, 4'-[ (2-Bromo-1, 4-phenylene) di- (1E) -2, 1-ethenediyl]bisphenol; (trans, trans) -1-Bromo-2, 5-bis- (4-hydroxy) styrylbenzene. Cas No. 872201-12-2. Molecular formula C22H17BrO2. Molecular weight 393.27. Laboratory Chemicals.
K-115, also called as Ripasudil or Glanatec, a selective ROCK inhibitor (IC50 =31 nM), is a promising emerging antiglaucoma drug, and was thus approved by the Japanese administrative authority in 2014. Synonyms: 4-fluoro-5-[[ (2S) -2-methyl-1, 4- diazepan- 1- yl] sulfonyl] isoquinoline Glanatec K-115 K115 compound ripasudil. Cas No. 223645-67-8. Molecular formula C15H18FN3O2S. Molecular weight 323.39. Laboratory Analytical Grades Available.
K-11777 is a potent, irreversible cysteine protease inhibitor. Besides? K11777 is not only a substrate but also a mechanism-based inhibitor of CYP3A4. Synonyms: 4-methyl-N- ( (S) -1-oxo-3-phenyl-1- ( ( (S, E) -5-phenyl-1- (phenylsulfonyl) pent-1-en-3-yl) amino) propan-2-yl) piperazine-1-carboxamide; APC-3316; APC3316; APC 3316; K-11777; K 11777; K11777; K 777; K-777; K777; CRA-3316; CRA3316; CRA 3316. Cas No. 233277-99-1. Molecular formula C32H38N4O4S. Molecular weight 574.74. Fine Chemicals.
K134 is a selective phosphodiesterase 3 (PDE3) inhibitor, and has been shown to exhibit more potent anti-platelet activity than cilostazol. In vivo studies have demonstrated the anti-thrombotic and anti-hyperplastic effects of K-134, and that these effect Synonyms: 1- cyclopropyl- 1- [ (1R, 2R) - 2- hydroxycyclohexyl] - 3- [3- [ (2- oxo- 1H- quinolin- 6- yl) oxy] propyl] urea; 6- (3- (3- cyclopropyl- 3- (2- hydroxycyclohexyl) ureido) propoxy) - 2 (1H) - quinolinone; K 134 compound; K- 134 compound; K134 compound; OPC 33509; OPC- 33509; K- 134. Cas No. 189362-06-9. Molecular formula C22H29N3O4. Molecular weight 399.48. Laboratory ACS Grades Available.
K145 is a selective sphingosine kinase-2 (SphK2) inhibitor and anticancer agent. K145 inhibited the activity of SphK2 in a dose-dependent manner with an IC50 of 4. 30±0. 06 M. K145 also exhibited inhibitory effects on the growth of U937 cells as well as a Synonyms: SphK2 inhibitor; K 145; K-145. Cas No. 1309444-75-4. Molecular formula C18H24N2O3S. Molecular weight 348.46. Laboratory AR Grades Available.
K145 hydrochloride
K145 (3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione) is a selective inhibitor of sphingosine kinase-2 (SphK2) and an anticancer agent. K145 selectively inhibited SphK2 in a dose-dependent manner with an IC50 of 4. 30 +/- 0. 0 Synonyms: SphK2 inhibitor; K 145 hydrochloride; K-145 hydrochloride. Cas No. 1449240-68-9. Molecular formula C18H25ClN2O3S. Molecular weight 384.92. Fine Chemicals.
K1 - PHYTONADIONE, USP
K1 - Phytonadione, USP. Categories: Vitamins, Pharmaceutical Products Dastech International
Taminco
K2, Cas Number 999-81-5 Taminco
K-252a
K-252a — see its active ingredient, namely K252a. LC Laboratories LC Laboratories
K252A
K252a, an analog of staurosporine, has been found to be a protein kinase inhibitor and exhibit antitumor activity at some extent. Synonyms: NZ0550000. Cas No. 99533-80-9. Molecular formula C27H21N3O5. Molecular weight 467.50. Reagent Grade Chemicals.
A staurosporine analogue isolated from a nocardiopsis strain; a potent inhibitor of protein kinase C. K252A exhibits potent antitumour activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents; also active against other kinases Synonyms: SF 2370. Cas No. 99570-78-2. Molecular formula C26H19N3O5. Molecular weight 453.5. Fine Chemicals.
K252a,>99%
K252a,>99%. Product No. K-2151. LC Laboratories LC Laboratories
K-252c
K-252c — see its active ingredient, namely K252c. LC Laboratories LC Laboratories
K252C
K252c, a metabolite product of Nocardiopsis Sp. , has been found to be a protein kinase C inhibitor and exhibit antiviral activities against GCV-sensitive and -resistant strains at some extent. Synonyms: Staurosporine aglycone; Staurosporinone. Cas No. 85753-43-1. Molecular formula C20H13N3O. Molecular weight 311.40. Laboratory Chemicals.
K252c,>99%
K252c,>99%. Product No. K-9609. LC Laboratories LC Laboratories
K 41498
K 41498 is a potent and highly selective CRF2 receptor antagonist. Its Ki values are 425, 0. 66 and 0. 62 nM for human CRF1, CRF2? and CRF2? receptors respectively. It prevents sauvagine-stimulated cAMP accumulation in hCRF2?- and hCRF2?-expressing cells. I Synonyms: D- Phenylalanyl- L- histidyl- L- leucyl- L- leucyl- L- arginyl- L- lysyl- L- norleucyl- L- isoleucyl- L- ?- glutamyl- L- isoleucyl- L- ?- glutamyl- L- lysyl- L- glutaminyl- L- ?- glutamyl- L- lysyl- L- ?- glutamyl- L- lysyl- L- glutaminyl- L- glutaminyl- L- alanyl- L- alanyl- L- asparaginyl- L- asparagi. Cas No. 434938-41-7. Molecular formula C162H276N48O46. Molecular weight 3632.26. Laboratory Analytical Grades Available.
K 579, a cyanopyrrolidine compound, is a potent and slow-binding dipeptidyl peptidase IV (DPP IV) inhibitor. It has been shown to reduce blood DPP IV activity and attenuate glucose excursion following glucose loading in Zucker fatty rats. It reduces plasm Synonyms: (2S) -1-[[[4-Methyl-1- (2-pyrimidinyl) - 4- piperidinyl] amino] acetyl] - 2- pyrrolidinecarbonitrile; (S) -1- (4-Methyl-1- (2-pyrimidinyl) -4-piperidylamino) acetyl-2-pyrrolidinecarbonitrile; DPP IV Inhibitor IV. Cas No. 440100-64-1. Molecular formula C17H24N6O. Molecular weight 328.41. Laboratory Chemicals.
K6PC-5
K6PC-5 is a Sphingosine kinase 1 (SphK1 or SK1) activator that increases sphingosine-1-phosphate (S1P) production, an active metabolite of sphingolipid. S1P can modulate multiple cellular responses including [Ca2+] signaling, growth, survival, and differe Synonyms: Dihydroxyisopropyl capryloylcaprylamide; Decanamide, 2-hexyl-N- (2-hydroxy-1- (hydroxymethyl) ethyl) -3-oxo. Cas No. 756875-51-1. Molecular formula C19H37NO4. Molecular weight 343.5. Reagent Grade Laboratory Chemicals.
K-7174 is a novel orally active, potent proteasome inhibitor. K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases. K-7174 kills bortezomib-resistant myeloma cells carrying a ?5-subuni Synonyms: K-7174; K 7174; K7174. Cas No. 191089-59-5. Molecular formula C33H48N2O6. Molecular weight 568.74. Fine Chemicals.
K-7174 dihydrochloride
K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, without obvious side effects in a murine myeloma model. Moreover, K-7174 kills bortezomib-resist Synonyms: 1, 4-bis ( (E) -5- (3, 4, 5-trimethoxyphenyl) pent-4-en-1-yl) -1, 4-diazepane dihydrochloride; K7174; K 7174; K-7174; K-7174-2HCl; K-7174 dihydrochloride. Cas No. 191089-60-8. Molecular formula C33H50Cl2N2O6. Molecular weight 641.67. Laboratory ACS Grades Available.
K-858 is a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells. K858 blocked centrosome separation, activated the spindle checkpoint, and induced mitotic arrest in cells accompanied by the formation of monopolar Synonyms: K-858; K 858; K858. Cas No. 72926-24-0. Molecular formula C13H15N3O2S. Molecular weight 277.34. Laboratory Chemicals.
KAAD-Cyclopamine
KAAD-Cyclopamine is a sonic hedgehog antagonist known to target Smoothened. Hedgehog signaling is involved in embryogenesis as well as cancer progression. KAAD-Cyclopamine has been utilized to halt the migration or proliferation of a variety of cancer cel Cas No. 306387-90-6. Molecular formula C44H63N3O4. Molecular weight 697.99. Laboratory AR Grades Available.
Kadsuracoccinic acid A
Kadsuracoccinic acid A is a natural compound isolated from the herb of Kadsura coccinea. Cas No. 1016260-22-2. Molecular formula C30H44O4. Molecular weight 468.678. Laboratory Analytical Grades Available.
Kadsurenin D
Synonyms: (1S, 5S, 6R, 7R) -5-allyl-7- (3, 4-dimethoxyphenyl) - 3- methoxy- 6- methyl bicyclo [ 3.2.1] oct- 3- ene- 2, 8-dione. Cas No. 140669-89-2. Molecular formula C21H24O5. Molecular weight 356.412. Laboratory Reagents.
Kadsuric acid
Kadsuric acid isolated from the fruits of Schisandra sphenanthera. Synonyms: 3, 4- secolanosta- 4 (28) , 9 (11) , 24Z- triene- 3, 26- dioic acid; (Z, 6R) - 6- [ (3aR, 6S, 7S, 9aS, 9bS) - 6- (2- carboxyethyl) - 3a, 6, 9b- trimethyl- 7- prop- 1- en- 2- yl- 1, 2, 3, 4, 7, 8, 9, 9a- octahydrocyclopenta [ a] naphthalen- 3- yl] - 2- methylhept- 2- enoic acid. Cas No. 62393-88-8. Molecular formula C30H46O4. Molecular weight 470.7. Laboratory Reagents.
Kadsurin A
Kadsurin A isolated from the fruits of Kadsura longipedunculata. Synonyms: (2S, 3R, 3aS, 7aR) -2- (1, 3-Benzodioxol-5-yl) -3, 3a, 7, 7a-tetrahydro-3a, 7a-dimethoxy-3-methyl-5- (2-propenyl) -6 (2H) -benzofuranone. Cas No. 99340-07-5. Molecular formula C21H24O6. Molecular weight 372.4. Reagent Grade Chemicals.
Kaempeerol-3-O-glucorhamnoside
Kaempferol-3-O-glucosyl(1-2)rhamnoside from Ginkgo biloba and a reappraisal of other gluco(1-2, 1-3 and 1-4)rhamnoside structures Cas No. 40437-72-7. Molecular formula C27H30O15. Laboratory Reagents.
Kaempferide
Kaempferide is an O-methylated flavonol. It can be found in Kaempferia galanga (aromatic ginger). The enzyme kaempferol 4'-O-methyltransferase uses S-adenosyl-L-methionine and kaempferol to produce S-adenosyl-L-homocysteine and kaempferide. Synonyms: Kaempferol 4'-O-methyl ether. Cas No. 491-54-3. Molecular formula C16H12O6. Molecular weight 300.26. Laboratory Analytical Grades Available.
Kaempferitrin
Kaempferitrin isolated from the root of Kaempferia galangal L. It stimulates glucose-metabolizing enzymes and promotes glucose homeostasis. Synonyms: 3, 7-Bis[ (6-deoxy-?-L-mannopyranosyl) oxy]-5-hydroxy-2- (4-hydroxyphenyl) -4H-1-benzopyran-4-one; 3, 7-Bis[ (6-deoxy-?-L-mannopyranosyl) oxy]-4', 5-dihydroxyflavone; kaempferol 3- O- ?- L- rhamnopyranosyl- 7- O- ?- L- rhamnopyranoside. Cas No. 482-38-2. Molecular formula C27H30O14. Molecular weight 578.5. Reagent Grade Laboratory Chemicals.
Kaempferol
Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources. Synonyms: Robigenin; Kaempherol; Kempferol; Populnetin; Rhamnolutein. Cas No. 520-18-3. Molecular formula C15H10O6. Molecular weight 286.23. Laboratory Reagents.
Kaempferol 3,4',7-triacetate
Cas No. 143724-69-0. Molecular formula C21H16O9. Laboratory AR Grades Available.
Kaempferol 3,7,4'-trimethyl ether
Kaempferol 3,7,4'-trimethyl ether isolated from the rhizomes of Curcuma aromatica. Synonyms: 5-hydroxy-3, 7-dimethoxy-2- (4-methoxyphenyl) -4-benzopyrone; 5-hydroxy-3, 7-dimethoxy-2- (4-methoxyphenyl) chromen-4-one. Cas No. 15486-34-7. Molecular formula C18H16O6. Molecular weight 328.3. Laboratory AR Grades Available.
Kaempferol-3-Glucuronide
Source: The herbs of Euphorbia lathyris Synonyms: 5, 7-Dihydroxy-2- (4-hydroxyphenyl) - 4- oxo- 4H- 1- benzopyran- 3- yl- beta- D- glucopyranosiduronic acid. Cas No. 22688-78-4. Molecular formula C21H18O12. Molecular weight 462.37. Fine Chemicals.
Kaempferol 3-neohesperidoside
Kaempferol 3-neohesperidoside is isolated from the herbs of Delphinium grandiflorum L. Synonyms: Kaempferol-3-O-glucorhamnoside. Cas No. 32602-81-6. Molecular formula C27H30O15. Molecular weight 594.5. Fine Chemicals.
Kaempferol-3-O- (2"-O-?-D- glucopyl) -?-D–rutinoside
Kaempferol-3-O-(2"-O-?-D- glucopyl)-?-D–rutinoside is a compound of the flavonoid class. Cas No. 55696-58-7. Molecular formula C33H40O20. Molecular weight 756.66. Laboratory Analytical Grades Available.
Kaempferol-3-O- (6-Malonyl-Glucoside)
Synonyms: 3-[[ (2R, 3S, 4S, 5R, 6S) -6-[5, 7-dihydroxy-2- (4-hydroxyphenyl) -4-oxochromen-3-yl]oxy-3, 4, 5- trihydroxyoxan- 2- yl] methoxy] - 3- oxopropanoic acid. Cas No. 81149-02-2. Molecular formula C24H22O14. Molecular weight 534.43. Laboratory ACS Grades Available.
Kaempferol 3-O- (6''-O-acetyl) glucoside-7-O-rhamnoside
Kaempferol 3-O-(6''-O-acetyl)glucoside-7-O-rhamnoside is isolated from the roots of Ligusticum jeholense Nakai et Kitag. Synonyms: Kaempferol 3- (6''-acetylglucoside) 7-rhamnoside. Cas No. 66465-24-5. Molecular formula C29H32O16. Molecular weight 636.56. Reagent Grade Chemicals.
Kaempferol 3-O-arabinoside
Kaempferol 3-O-arabinoside comes from the roots of Ligusticum jeholense Nakai et Kitag. Synonyms: Kaempferol 3-O-?-L-arabinoside. Cas No. 99882-10-7. Molecular formula C20H18O10. Molecular weight 418.4. Reagent Grade Laboratory Chemicals.
Kaempferol 3-O-gentiobioside
Kaempferol 3-O-rhamninoside
Kaempferol 3-O-rhamninoside is a natural compound isolated from the seeds of Patrinia villosa Juss. Synonyms: 3- [ (2S, 3R, 4S, 5R, 6R) - 6- [ [ (2R, 3R, 4R, 5S, 6S) - 3, 5- dihydroxy- 6- methyl- 4- [ (2S, 3R, 4R, 5R, 6S) - 3, 4, 5- trihydroxy- 6- methyloxan- 2- yl] oxyoxan- 2- yl] oxymethyl] - 3, 4, 5- trihydroxyoxan- 2- yl] oxy- 5, 7- dihydroxy- 2- (4- hydroxyphenyl) chromen- 4- one. Cas No. 83170-31-4. Molecular formula C33H40O19. Molecular weight 740.66. Laboratory Chemicals.
Kaempferol 3-?-Sophoroside
Kaempferol 3-?-Sophoroside is a derivative of Kaempferol with antibacterial and antiviral activities. Synonyms: Sophoraflavonoloside; 3-[ (2S, 3R, 4S, 5S, 6R) -4, 5-dihydroxy-6- (hydroxymethyl) -3-[ (2S, 3R, 4S, 5S, 6R) -3, 4, 5-trihydroxy-6- (hydroxymethyl) oxan-2-yl]oxyoxan-2-yl]oxy-5, 7-dihydroxy-2- (4-hydroxyphenyl) chromen-4-one. Cas No. 19895-95-5. Molecular formula C27H30O16. Molecular weight 610.521. Laboratory Chemicals.
Kaempferol 3-sophoroside-7-glucoside
Kaempferol 3-sophoroside-7-glucoside is a compound of the flavonoid class found in the stems of Equisetum hyemale L. Synonyms: Kaempferol 3- O- beta- D- [ beta- D- glucopyranosyl- (1->2) - glucopyranoside] - 7- O- beta- D- glucopyranoside; Kaempferol 3-O-beta-D-sophoroside 7-O-beta-D-glucopyranoside; Kaempferol 3-O-beta-sophoroside 7-O-beta-glucoside. Cas No. 55136-76-0. Molecular formula C33H40O21. Molecular weight 772.66. Fine Chemicals.
Kaempferol 3-sophoroside-7-rhamnoside
Kaempferol 3-sophoroside-7-rhamnoside is a compound of the flavonoid class found in the herbs of Elaeagnus multiflora Thunb. Cas No. 93098-79-4. Molecular formula C33H40O20. Molecular weight 756.66. Laboratory AR Grades Available.
KaempferoL-4-glucoside
Cas No. 52222-74-9. Fine Chemicals.
Synonyms: 4', 5, 7-Trimethoxyflavonol; 2- (4-Methoxyphenyl) -3-hydroxy-5, 7- dimethoxy- 4H- 1- benzopyran- 4- one;. Cas No. 1098-92-6. Molecular formula C18H16O6. Molecular weight 328.316. Laboratory Reagents.
Kaempferol-7-O-glucoside
Kaempferol-7-O-?-D-glucopyranoside is extracted from the herbs of Hosta plantaginea. Synonyms: 2- (4- Hydroxyphenyl) - 3, 5- dihydroxy- 7- (?- D- glucopyranosyloxy) - 4H- 1- benzopyran- 4- one; 7- [ (?- D- Glucopyranosyl) oxy] - 3, 4', 5- trihydroxyflavone; Kaempferol 7- monoglucoside; 7- (?- D- Glucopyranosyloxy) - 3, 5- dihydroxy- 2- (4- hydroxyphenyl) - 4H- 1- benzopyran- 4- one; Glucosy. Cas No. 16290-07-6. Molecular formula C21H20O11. Laboratory Analytical Grades Available.
Kaempferol 7-O-neohesperidoside
Synonyms: Kaempferol- 7- O- alpha- L- rhamnoside- D- glucoside. Cas No. 17353-03-6. Molecular formula C27H30O15. Molecular weight 594.52. Laboratory ACS Grades Available.
Kaempferol 7-O-rhamnoside
Kaempferol 7-O-rhamnoside isolated from the herbs of Maytenus hookeri. Synonyms: Kaempferol-7-O-alpha-L-rhamnoside. Cas No. 20196-89-8. Molecular formula C21H20O10. Molecular weight 432.4. Reagent Grade Laboratory Chemicals.
Kaempferol tetraacetate
Kaempferol tetraacetate isolated from the herbs of Cudrania tricuspidata. Synonyms: 2- (4-Acetoxyphenyl) -4-oxo-4H-chroMene-3, 5, 7-triyl triacetate. Cas No. 16274-11-6. Molecular formula C23H18O10. Molecular weight 454.4. Laboratory Reagents.
Kahalalide F
Kahalalide F is one of a family of novel peptides isolated from the Hawaiian mollusk, Elysia rufescens. It is currently in Phase II trials for hepatocarcinoma. Kahalalide F (KF) is a novel antitumor drug of marine origin under clinical investigation. KF Synonyms: Kahalalide F; PM-92102. Cas No. 149204-42-2. Molecular formula C75H124N14O16. Molecular weight 1477.899. Reagent Grade Chemicals.
Kahweofuran
Synonyms: kahweofuran; TomatoLycopene; Spicery; 2, 3-Dihydro-6-methylthieno[2, 3-c]furan; 6-Methyl-2, 3-dihydrothieno[2, 3-c]furan. Cas No. 26693-24-3. Molecular formula C7H8OS. Molecular weight 140.20. Laboratory ACS Grades Available.
Kahweol
Kahweol. CAS No: 6984-43-5 Sarchem Laboratories
KAI-407
KAI-407, an imidazopyrazine derivative, has been found to be probably effective to restrain plasmodium and used against malaria. Synonyms: KAI-407; KAI 407; KAI407; N- (4-cyanophenyl) -N-methyl-3- (4- (trifluoromethyl) phenyl) imidazo[1, 2-a]pyrazine-6-carboxamide. Cas No. 1513879-18-9. Molecular formula C22H14F3N5O. Molecular weight 421.38. Laboratory Reagents.
Kainic acid
Kainic acid is a naturally occurring neuroexcitatory amino acid. It is a selective agonist for a subtype of ainate-class ionotropic glutamate receptor found in seaweed. It increases production of mitochondrial dysfunction, reactive oxygen species and apop Synonyms: (2S, 3S, 4S) -3- (carboxymethyl) -4- (prop-1-en-2-yl) pyrrolidine-2-carboxylic acid; 2- Carboxy- 3- carboxy methyl - 4- isopropenylpyrrolidine; (-) -?-Kainic Acid; Digenic Acid; Digenin; Helminal; L-?-Kainic Acid; ?-Kainic Acid. Cas No. 487-79-6. Molecular formula C10H15NO4. Molecular weight 213.23. Laboratory Chemicals.
Kaiso 24WG
Kaiso is a unique formulation of Lambda Cyhalothrin, made from the patented Sorbie technology, that can be formulated for packaging and loader handling as a Wettable Granule and functions as an Emulsifiable Concentrate when it is mixed with water. The unique formulation characteristics of Kaiso provide a source of Lambda Cyhalothrin that couples the handling benefits of a Wettable Granule with the quick knockdown characterisitics of an emulsifiable concentrate. Nufarm USA
Kajiichigoside F1
Kajiichigoside F1 is a triterpenoid compound found in the roots of Rosa rugosa. Kajiichigoside F1 exhibits anti-inflammatory and hepatoprotective activities in vivo and antiviral activity in vitro. Synonyms: [ (2S, 3R, 4S, 5S, 6R) - 3, 4, 5- trihydroxy- 6- (hydroxymethyl) oxan- 2- yl] (1R, 2R, 4aS, 6aR, 6aS, 6bR, 8aR, 10S, 11R, 12aR, 14bS) - 1, 10, 11- trihydroxy- 1, 2, 6a, 6b, 9, 9, 12a- heptamethyl- 2, 3, 4, 5, 6, 6a, 7, 8, 8a, 10, 11, 12, 13, 14b- tetradecahydropicene- 4a- carboxylate. Cas No. 95298-47-8. Molecular formula C36H58O10. Molecular weight 650.85. Laboratory ACS Grades Available.
Kakadu Plum Extract
Kakadu Plum Extract. Category: Natural Extracts Global Essence
KALAUNJI Natural Oil
KALAUNJI Essential Oil - Natural Oils. BOTANICAL NAME: Nigella Sativa. Carillon Green is a worldwide chemical distributor Carillon Green Inc.
Kaliotoxin
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0. 1, 1. 1 and 25 nM for KV1. 3, KV1. 1 and KV1. 2 channels) respectively). Also inhibits Ca2+-activated K+ channels. Cas No. 145199-73-1. Molecular formula C171H283N55O49S8. Molecular weight 4149.94. Laboratory AR Grades Available.
kaliumdimethyldithiocarbamate (KDDC)
KDDC, Cas Number 128-03-0 Taminco
KALLIKREIN. CAS 9001-01-8 Alfa Chem
Kallikrein Inhibitor
Kallikrein Inhibitor, a synthetic peptide, is a serine protease inhibitor that inhibits kallikrein and plasmin, and can attenuate breast cancer cell invasion. Synonyms: Unk- Phe- Arg- Ser- Val- Gln- NH2; (2S) - 2- [ [ (2S) - 2- [ [ (2S) - 2- [ [ (2S) - 2- [ [ (2S) - 2- [ [ (2S) - 1- acetylpyrrolidine- 2- carbonyl] amino] - 3- phenylpropanoyl] amino] - 5- (diaminomethylideneamino) pentanoyl] amino] - 3- hydroxypropanoyl] amino] - 3- methylbutanoyl] amino] pentanediamide. Cas No. 97145-43-2. Molecular formula C35H55N11O9. Molecular weight 773.88. Laboratory ACS Grades Available.
Kalopanaxsaponin H
Kalopanaxsaponin H is extracted from the herbs of Hedera nepalensis K. Koch var. sinensis (Tobl. ) Rehd. It has antidiabetic activity. Synonyms: Macranthoside A. Cas No. 128730-82-5. Molecular formula C47H76O17. Laboratory ACS Grades Available.
Kalzinol (9CI)
KambaMaster
KambaMaster is a selective, post-emergent herbicide that provides tough, long lasting control for a broad spectrum of annual, biennial, and perennial broadleaf weeds and brush in grass forages and selected row crops. Nufarm USA
Kamebanin
Kamebanin, a natural diterpenoid found in the herbs of the herbs of Rabdosia excisa (Maxim. )Hara, exhibits the activity of antibacterial. Kamebanin has efficient cytotoxic activity against HeLa and HL-60 cells. Synonyms: (1?, 5?, 7?, 8?, 9?, 10?, 13?, 14R) -1, 7, 14-Trihydroxykaur-16-en-15-one. Cas No. 39388-57-3. Molecular formula C20H30O4. Molecular weight 334.5. Laboratory AR Grades Available.
kanamycin
The tests forwarded to overseas Mitsubishi Chemical Holdings America Inc


44th NAACP Image Awards Pre-Show Gala Reception #NAACPImageAwards, a set on Flickr.
Mingle Media TV and Red Carpet Report host, Linda Antwi, were invited to cover the 44th NAACP Image Awards Pre-Gala Reception at Vibiana in Los Angeles. The gala reception was set prior to the Awards ceremony which will be held tonight Friday Feb. 1 and broadcast from 8-10 PM ET on NBC.
Founded in 1909, the NAACP is the nation's oldest and largest civil rights organization. Its members throughout the United States and the world are the premier advocates for civil rights in their communities, conducting voter mobilization and monitoring equal opportunity in the public and private sectors. For more information on the NAACP Image Awards, please visit www.naacpimageawards.net.
44th NAACP Image Awards Nominee Luncheon, a set on Flickr.
Mingle Media TV and Red Carpet Report host, Linda Antwi, were invited to cover the 44th NAACP Image Awards Nominee's Luncheon at the Montage Beverly Hills. The luncheon is a precursor to the Awards ceremony which will be held on Friday Feb. 1, 8-10 p.m. ET on NBC.
Watch our interviews on YouTube with Aaron D Spears, Andrew Tyree, Javon Johnson, Angell Conwell, Chandra Wilson, Craig Robinson, Erik Valdez, Hosea Chanchez, Janine Sherman Barrois, Kareem Abdul-Jabbar, Kellita Smith, Niecy Nash, Rockmond Dunbar, Rodney Saulsberry, Shenell Edmonds, Sonia Jackson Myles, Terry Ellis, Tatyana Ali, Tory Kittles, Tristan Wilds, and Yvette Nicole Brown.
We'd like to congratulate all of the nominees that were announced at this mornings 43rd NAACP Image Awards press conference in Beverly Hills at the Paley Center for Media. The nominees were announced by Vanessa Williams, Tracee Ellis Ross, Corey Reynolds, and Craig Robinson.
Please be sure to save the date for the live show on NBC where the winners will be announced during the two-hour star-studded event.
ABC and CBS lead the nominees in the TV categories with 18 and 16 nominations respectively, followed by BET and HBO both with 15. In the recording category, Columbia Records leads with eight nominations, followed by Warner Bros. Records with five nominations and Elektra Records with four nominations. Dreamworks Pictures/Touchstone Pictures/Participant Media lead with eight nominations, while Focus Features and TriStar Pictures followed with seven, and Universal Pictures with five in the motion picture category.
Please visit the NAACP Image Awards website at http://www.naacpimageawards.net for the complete list of the 42nd NAACP Image Awards' Nominees.
Event sponsors for the 43RD NAACP Image Awards include UAW/Chrysler, Hyundai, FedEx, Wells Fargo, Ford Motor Company, and Bank of America.
"2011 BET Awards""25/8" Mary J. Blige"2Grieve 2Gether: A Journal from the Heart Helping Survivors & Supporters Navigate the Healing Process" Denise Hall Brown"4" Beyoncé"A Defining Moment" Patricia Duncan"A Silken Thread" Brenda Jackson"A Singular Woman: The Untold Story of Barack Obama's Mother" Janny Scott"Afrodiaspora" Susana Baca"AllAmerican Muslim""Anderson""Attack the Block""Beats"Being Elmo: A Puppeteer's Journey""Best Thing I Never Had" Beyoncé"Black Girls Rock!""Boundaries" Elizabeth Nunez"Carnival Fever" Brother B"Dora The Explorer""F.A.M.E" Chris Brown"Fool for You feat. Melanie Fiona" Cee Lo Green"Go"Hear My Call" Jill Scott"I Can Be President: A Kid'sEye View""I Remember Me" Jennifer Hudson"I Smile" Kirk Franklin"I Was Here" Beyoncé"I Will Follow""In the Land of Blood and Honey""Jumping the Broom""Kinyarwanda""Lasers" Lupe Fiasco"Law & Order: Special Victims Unit""Live at 2011 New Orleans Jazz & Heritage Festival" Boukman Eksperyans"Love That Girl!""Malcolm X: A Life of Reinvention" Manning Marable"MOOZlum""My Family Tree""My Song" Harry Belafonte"No Higher Honor: A Memoir of My Years in Washington" Condoleezza Rice"Oprah Presents: Master Class""Oprah's Lifeclass""Pariah""Prince! Behind the Symbol""Reed Between the Lines""Say Amen"Silver Sparrow" Tayari Jones"Sister Citizen: Shame"So In Love feat. Anthony Hamilton" Jill Scott"Someone Like You" Adele"Sounds of Blackness" Sounds of Blackness"Sunday Best""Super Rich" Russell Simmons"The Cosmopolitan Canopy" Elijah Anderson"The Doctors""The First Grader""The First Grader" Alex Heffes"The Game""The Help""The John Carlos Story" John Carlos"The Light of the Sun" Jill Scott"The Loom" Shella Gillus"The Plot Against Hip Hop: A Novel" Nelson George"The Strawberry Letter" Lyah Le Flore"The View""The Wealth Cure: Putting Money in Its Place" Hill Harper"The Wendy Williams Show""Tia & Tamera""Treme""Tyler Perry's House of Payne""UNCF An Evening of Stars Tribute to Chaka Khan""We the Animals" Justin Torres"Where You At" Jennifer Hudson"Who's Afraid of Post Blackness?: What It Means to Be Black Now" Toure1st & 15th/Atlantic Records2Lift 1Up PublishingA SeparationA.N.T. FarmabcAbove All"Adepero Oduye "Pariah"AFFRMAgain" Reshonda Tate BillingsleyAkashic BooksAlfre Woodard "Memphis Beat"Algonquin BooksAmber Riley "Glee"American Idoland Black Women in America" Melissa HarrisPerryAndre Braugher "Men of A Certain Age"Anika Noni Rose "Law & Order: Special Victims Unit"Anthony HamiltonAnthony Mackie "The Adjustment Bureau"Archie Panjabi "The Good Wife"Arista RecordsAtlantic RecordsBallantine/Random HouseBenchmark Entertainment/MSM Music GroupBETBeyoncéBig Beat/Atlantic Recordsboardwalk empireBoyz II MenBruno MarsBryce Dallas Howard "The Help"CBSCee Lo GreenCee Lo Green feat. Melanie FionaChandra Wilson "Grey's Anatomy"Charles Parnell "Pariah"China Anne McClain "A.N.T. Farm"Chris BrownCicely Tyson "The Help"Columbia PicturesColumbia RecordsCommittedCommonCorey Reynolds "The Closer"Craig Robinson "The Office"Crown PublishersDamon Wayansdancing with the starsDave ZirinDiahann Carroll "White Collar"Diego! Go!"Diggy SimmonsDisney ChannelDocumentaryDon Cheadle "The Guard"DreamWorks Pictures/Participant Media/Touchstone PicturesDulé Hill "Psych"Eddie Murphy "Tower Heist"Elektra RecordsEmma Stone "The Help"EpicFilmDistrictFocus FeaturesFOXFree PressGabourey Sidibe "The Big C"Gallery BooksGeffenGotham BooksGrey's AnatomyGroup or CollaborationGuideposts BooksHarlequin Kimani PressHaymarket BookshboHill Harper "CSI: NY"Houghton Mifflin HarcourtIce T "Law & Order: Special Victims Unit"IJABA Publishing Inc.Inc.Island Def Jam Music GroupJ.B. Smoove "Curb Your Enthusiasm"James PickensJanus FilmsJeffrey Wright "The Ides of March"Jennifer HudsonJill ScottJive RecordsJr.Jr. "Grey's Anatomy"Jr. "Happy Endings"Keke Palmer "True JacksonKeshia Knight Pulliam "Tyler Perry's House of Payne"Khandi Alexander "Treme"Kim Wayans "Pariah"King Chero RecordsKnopfL.L. Cool J "NCIS: Los Angeles"Lance Robertson "Yo Gabba Gabba"Landau Eugene MurphyLaurence Fishburne "Contagion"Laz Alonso "Jumping the Broom"Le HavreLedisiLeon Thomas III "Victorious"lifeLITERATURE CATEGORIESLoretta Devine "Grey's Anatomy"Luaka BopMalaco Music GroupMalcolmJamal Warner "Reed Between the Lines"Mary J. BligeMary J. Blige feat. DrakeMaya Rudolph "Bridesmaids"Maya Rudolph "Up All Night"Mike Epps "Jumping the Broom"Mindless Behaviormodern familyMOTION PICTURE CATEGORIESMunckMixNational Geographic EntertainmentnbcNelsan Ellis "True Blood"Nick Cannon "Up All Night"nickelodeonOctavia Spencer "The Help"Oliver Litondo "The First Grader"Omar Epps "House M.D."Outstanding Actor in a Comedy SeriesOutstanding Actor in a Drama SeriesOutstanding Actor in a Motion PictureOutstanding Actress in a Comedy SeriesOutstanding Actress in a Drama SeriesOutstanding Actress in a Motion PictureOutstanding AlbumOutstanding Children's ProgramOutstanding Comedy SeriesOutstanding DocumentaryOutstanding Drama SeriesOutstanding DuoOutstanding Female ArtistOutstanding Foreign Motion PictureOutstanding Independent Motion PictureOutstanding Literary Work Biography/AutoBiographyOutstanding Literary Work Debut AuthorOutstanding Literary Work FictionOutstanding Literary Work NonFictionOutstanding Male ArtistOutstanding Motion PictureOutstanding Music VideoOutstanding New ArtistOutstanding Performance in a Youth/ Children's ProgramOutstanding Reality SeriesOutstanding SongOutstanding Supporting Actor in a Comedy SeriesOutstanding Supporting Actor in a Drama SeriesOutstanding Supporting Actor in a Motion PictureOutstanding Supporting Actress in a Comedy SeriesOutstanding Supporting Actress in a Drama SeriesOutstanding Supporting Actress in a Motion PictureOutstanding Talk SeriesOutstanding Variety Series or SpecialOutstanding World Music AlbumOWN: Oprah Winfrey NetworkPaula Patton "Jumping the Broom"Penguin GroupPhil Morris "Love That Girl!"Pooch Hall "The Game"RCA RecordsRECORDING CATEGORIESRegina King "SouthLAnd"Rhymes & Life: The Travels of A Tribe Called Quest"Riverhead BooksSandra Oh "Grey's Anatomy"Screen GemsSeries or SpecialShowtimeSofia Vergara "Modern Family"Sony Pictures ClassicsSounds of BlacknessStereotypesStreamline/Conjunction/Interscope RecordsStyle NetworkSubmarine DeluxeSyndicatedTaraji P. Henson "Person of Interest"Tatyana Ali "Love That Girl!"Taye Diggs "Private Practice"TBSTELEVISION CATEGORIESTerry Crews "Are We There Yet?"The Africa Channelthe good wifeThe RootsTheatrical or TelevisionTia MowryHardrict "The Game"TLCtnttower heistTracee Ellis Ross "Reed Between the Lines"Tracy Morgan "30 Rock"TriStar PicturesTV OneUniversal PicturesUSAUSA NetworkVanessa Williams "Desperate Housewives"Varese SarabandeVerity Gospel Music GroupVerve ForecastVikingVin Diesel "Fast Five"Viola Davis "The Help"VP"W. W. Norton & CompanyWarner Bros. PicturesWarner Bros. RecordsWendell Pierce "Treme"Wendy Raquel Robinson "The Game"Wynter GordonYale University PressZendaya Coleman "Shake It Up"Zoë Saldana "Colombiana"
As we await the 42nd NAACP Image Awards show on FOX tonight (8:00-10:00 PM ET live/PT) we're excited to say that we are looking forward to seeing legendary gospel singer Mavis Staples perform with the award-winning a cappella group Committed, broadcast live from Los Angeles' historic Shrine Auditorium.
Christian R&B vocalist Deitrick Haddon and Contemporary Jazz instrumentalist Boney James will also be there and perform at the annual awards show.
Who will you see on tonight's NAACP Award show? Expect to see the lovely actress Angela Bassett, NAACP Chairwoman Roslyn M. Brock, actress Loretta Devine, singer Jason Derülo, actress/singer Kat Graham, actor Dulé Hill, actor Anthony Mackie, Judge Greg Mathis, actresses Tia and Tamera Mowry, actress Sandra Oh, comedian Russell Peters and actress Anika Noni Rose along with Halle Berry, LL Cool J, Affion Crockett, Kimberly Elise, Kerry Washington and Vanessa Williams.
The show will be hosted by Wayne Brady and Holly Robinson Peete and executive-produced by Vicangelo Bulluck, the special celebrates the accomplishments of people of color working in literature, music, television and film including the Chairman's Award recipient Surgeon General Regina M. Benjamin and President's Award recipient General Colin L. Powell.
Event sponsors for the 42nd NAACP Image Awards include UAW/Chrysler, Walgreens, Wells Fargo, FedEx, Hyundai, Southwest Airlines, Anheuser-Busch, AT&T, Bank of America, Ford Motor Company, Pepsi and American Airlines.
Founded on Feb. 12, 1909, the National Association for the Advancement of Colored People (NAACP) is the nation's oldest and largest civil rights organization. Its half-million adult and youth members throughout the United States and the world are the premier advocates for civil rights in their communities, and monitor equal opportunity in the public and private sectors. For more information on the NAACP IMAGE AWARDS, please visit http://www.naacpimageawards.net.
Mingle Media TV was invited to cover the 42nd NAACP IMAGE AWARDS Nominees? Luncheon red carpet at the Beverly Hills Hotel. The event honors those nominated for their outstanding achievements in television, recording, literature, and motion picture. Hosted by Host Affion Crockett (Actor/Comedian) and joined by Antwone Fisher (Director/Screenwriter),Chandra Wilson (Actress), Craig Robinson (Actor/Comedian), Debra Martin Chase (Producer),George Tillman (Director/Producer), James Pickens, Jr. (Actor), Jason Derulo (Singer/Songwriter),LaVan Davis (Singer/Actor), Louis Gossett Jr. (Actor), Millicent Shelton (Director), Paris Barclay(Director/Producer), Sara Ramirez (Actress), Tatyana Ali (Actress/ Singer) and other fellow nominees. Founded on Feb. 12, 1909, the National Association for the Advancement of Colored People (NAACP) is the nation?s oldest and largest civil rights organization. Its half-million adult and youth members throughout the United States and the world are the premier advocates for civil rights in their communities, and monitor equal opportunity in the public and private sectors. For more information on the NAACP IMAGE AWARDS, please visit http://www.naacpimageawards.net. This year's 42nd NAACP IMAGE AWARDS will be broadcast live on Friday, March 4, 2011 on FOX. Thanks to the Lippin Group for inviting us to come out and cover this event. For more information visit http://www.lippingroup.com. For more red carpet coverage, visit Mingle Media TV at http://www.minglemediatv.com/redcarpetreport.html.


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Exeter Courthouse spotlights two local artists
For Choices
A reception for The Exeter Courthouse Gallery's newest show at 2 p.m. Sunday, April 3 reunites Jerry Smith from Visalia and George Tonimoto from Porterville.
Their last show two years ago in this same gallery was the best received and attended in the gallery's history.
Jerry's newest show "Photographs Reimagined" differs from the last show, depicting landscapes in more realistic terms, toward highly manipulated images that at times may not resemble photographs at all.
Visalia Players bring back memories with 'Outgoing Tide'
"As an artist, I've drawn and painted for longer than I have used a camera. To those believing a photograph should remain true to the original composition," he said. "I see what is just the beginning. The process to complete each photograph requires more time at the computer than in the field."
Much of what will hang in the new show are photographs from up to 10 years ago made around California, Arizona and Oregon. These are photographs he liked but had put away feeling that they needed something extra.
Jerry grew up in Exeter, only a stone's throw from the Exeter Gallery and is now retired and living in Visalia.
George Tonimoto shares the same Central Valley roots growing up in Sanger with both graduating from Fresno State. George is retired from the Porterville Developmental Center where he taught arts and crafts.
First Friday gears up for spring
In retirement, George has perfected his painting skills studying with Tom Howell and Margaret K. Wheeler at Porterville College.
George is well respected in the art world having shown extensively in area galleries while a member of the Porterville Art Association, the Visalia Art League and the Tulare Palette Club.
His art goes beyond personal satisfaction toward a means to communicate his thoughts. He feels success means drawing and painting and through that, he feels good, making money is not the point.
George credits his grandfather for the family's artistic gifts. His sister Joyce is an accomplished artist in Fresno. A show is an opportunity for him to bring family and friends together, enjoying the shared experience of art.
A reception for the artists will be held at the Exeter Courthouse Art Gallery is from 2-4 p.m. Sunday April 3. The show will remain hanging thru June. The gallery is located in Exeter, 125 S. B St. and is open 10 a.m. to 4 p.m. Saturdays and noon to 4 p.m. Sundays.

redpajama_set_name: RedPajamaCommonCrawl


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House Dems say Big Oil pays lip service on climate| MENAFN.COM
House Dems say Big Oil pays lip service on climate
(MENAFN- AFP)
Congressional Democrats accused the petroleum industry of paying lip service to climate change Thursday, releasing an analysis that showed little effort by oil majors to advance green policies in Washington.
A memo prepared ahead of Thursday's hearing with Big Oil chief executives said the industry -- while professing to support the Paris Climate Agreement and carbon pricing -- has done virtually no lobbying in Washington to enact policies consistent with those goals.
"The companies appear to be using their praise of the Paris Agreement and carbon pricing to bolster their own public image while they continue to produce billions of barrels of fossil fuel and invest in new oil and gas extraction -- actions that are making the climate crisis worse," said an eight-page memo from the House Oversight Committee.
For example, ExxonMobil reported only one instance of lobbying on the Paris Agreement between 2015 and 2021, while lobbying 74 times against a bill to repeal tax breaks and 36 times on US tax cuts approved in 2017.
Chevron, which like ExxonMobil has publicized its commitment to low-carbon energy, lobbied just eight times on carbon pricing legislation since 2011, less than one percent of its total lobbying over the period, the report said.
Thursday's hearing is titled "Fueling the Climate Crisis: Exposing Big Oil's Disinformation Campaign to Prevent Climate Action."
Committee Chair Carolyn Maloney, a New York Democrat, likened the hearing to a famous 1994 congressional hearing in which leaders of large tobacco testified under oath that nicotine was not addictive.
"I hope that today's hearing represents a turning point for Big Oil," Maloney said. "I hope that today the witnesses will finally own up to the industry's central role in this crisis and become part of the change we need."
In an opening statement to the committee, ExxonMobil Chief Executive Darren Woods said ExxonMobil has been "vocal and transparent" in support of climate policies, but that "there are no easy answers" to address climate change while fueling the economy.
Mike Sommers, president of the American Petroleum Institute, said the oil industry was working to address climate change, but that oil and gas production would be needed for the foreseeable future.


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Home People & Skills ECAM LaSalle & Confluences to offer Industry 4.0 Manufacturing Engineering degree
ECAM LaSalle & Confluences to offer Industry 4.0 Manufacturing Engineering degree
Confluences has announced it will support ECAM LaSalle to launch the first sustainable Manufacturing Engineering curriculum in 2021 in Cambodia. The partnership will target manufacturing 4.0 and will include the Institut de Technologie du Cambodge (ITC – the leading engineering University in Cambodia).
ECAM LaSalle & Confluences to offer Industry 4.0 Manufacturing Engineering degree in Cambodia
In an announcement released by Confluences this week, they said: "This program aims to meet the needs of Industry 4.0 in Cambodia and South-East Asia by training students to incorporate digital technology into the manufacturing and logistics management processes with minimal environmental and social impact."
Confluences are a business and startup incubator in the Kingdom of Cambodia and ASEAN. The French-Cambodian team has more than 15 years of experience in the Kingdom of Cambodia and their website says "Confluences specialises in providing solutions and support to companies seeking to break into or expand within the Cambodian and Southeast Asian markets."
Didier Desplanche, Managing Director ECAM Lasalle added "ECAM's vision is to help make the world more humane, responsible, and sustainable through education, science, and technology. We are particularly proud to promote our vision in the Kingdom of Cambodia with the help of Confluences. Sharing the same values with Confluences has made our partnership with Confluences natural and constructive. Their knowledge and local network and capabilities are doing the rest."
Master's degree in Sustainable Manufacturing Engineering in Cambodia
ECAM LaSalle is partnering with Confluences to position this new curriculum in the higher education sector landscape in Cambodia. ECAM LaSalle is a French private Engineering graduate school which is highly regarded and been in operation since 1900.
Starting in September 2021, this 5-year program will deliver a double degree ECAM Engineering Master's degree + Master's degree from ITC. 25 students will be hosted in the first year and deliver a dual diploma in ECAM Engineering + Master's degree from ITC. Thereafter 40 students per year will be allowed to enrol.
The degrees will be taught in English, and Cambodian students will also have the opportunity to learn French to obtain a B2 level at the end of the program.
It was also announced that "some of these students will even be able to get scholarships to study in France. The program will also host students from France willing to study in Cambodia."
Lily Hé, COO of Confluences also said: "Helping Foreign and – notably French – private entities entering the market with projects that can benefit Cambodian society is part of Confluences DNA. We are particularly proud to contribute to the development of the higher education landscape in Cambodia with our partnership with ECAM Lasalle.
For us, the commitment of Graduate Engineering schools with the calibre of ECAM Lasalle is a strong sign of trust in the country and its future. This new program complements the efforts already made by French institutions to foster cooperation between France and Cambodia. Education, as we know, is a key sector for the future of the country, and it is important that private actors also take part in its development."
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Startupbootcamp HighTechXL: Patrick de Zeeuw at the launch of Startupbootcamp HighTechXL.
Patrick de Zeeuw at the launch of Startupbootcamp HighTechXL.
Patrick de Zeeuw, one of the co-founders of Startupbootcamp is one of the speakers at the public launch of HighTechXL, Eindhoven. Born in the city, Patrick has a particular affection for the South of the Netherlands. And it's clear that it's becoming the intellectual driving force for the rest of the country.


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Views by Drake
by Drew Allenon October 12, 2016 March 9, 2017 Leave a Comment on Views by Drake
By: Jack DeVault//
For Drake, it's lonely at the top. After bursting on the scene with So Far Gone in 2009, the Canadian superstar has produced nothing but hit after hit and has remained for the most part unchallenged at the top of the "hip-pop" world. Up until now, Drake's entire discography has consisted of wildly popular, fantastically composed tapes that have helped to mold his image into what it is today: an emotional, thoughtful, strong, and confused millennial. What has drawn millions to Drake over the last eight years has not been his looks, his flow, or his beats. Instead, it's been his relatability. Take Care's (2011) "Marvins Room" (a gentle, powerful track that features a drunk Drizzy rapping to his ex on the other end of the phone) is quintessential Drake. He understands the generation of broken hearts around him – he has experienced the heartbreak himself.
Views, Drake's latest album, moves away from what made Drake one of the top artists in the world. Substituting arrogance in place of relatability, Drizzy spends 80 minutes holding what is seemingly the biggest emotional dick-swinging contest he and 40 (his trusted producer) are capable of creating. The album is both egotistical and disjointed. It moves from faux emotional tracks to songs that not so subtly hint at his money, fame, and success. The dick-swinging is warranted: the man deserves to give himself some credit for creating the life he described on So Far Gone's "Successful" but on Views, it was overwhelming. 2016 Drake can successfully court most any girl in the world and he expects me, a lowly middle-class white kid, to sympathize with his "plight"? There is nothing relatable about Drake's girl swiping his Bugatti to get Kotex, as he raps in "Child's Play."
"I'd let her take my Volkswagen, but she'd have to put gas in it first."
In Views, there is too much Drizzy and not enough Aubrey. The album simply does not flow. Individually, each song is exceptionally produced and rather catchy but in a collective group, the tracks tell me nothing. At the end of "Hotline Bling", after an entire 80 minutes of Drake, I think to myself "that's it"? The album was carefully crafted to sell and sell some more. Many tracks on Views are so endlessly melodic and "radio-friendly" that they warrant a skip after the first 90 seconds- something I never thought I would be tempted to do while listening to a Drake album. By going all in on catchiness, Drake and 40 lost any sense of overall substance with the album. The songs just don't fit.
Even with its faults, Views features many great single hits. Tracks like "Controlla", "Too Good" and "One Dance" provide a warmth and bounce not yet seen on a Drake album and point toward a future of Caribbean flavored from the 6 God. For now, though, they are out of place – mixed in with a myriad of other beats to create an 80 minute hodgepodge of confusing beats.
Views, in its mediocrity, will forever be known as the album that could have cemented Drake's legacy forever. Instead, it's just another average album from a comfortable superstar that didn't live up to the hype. Drake's fall from the top of the game has begun.
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Drake Pop Rap
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We're blazing a new trail toward greater collaboration with a new community resource: Pathways to Health. Member agencies, institutions, businesses, foundations and other community-health stakeholders can access powerful data and use it to share ideas and complement each other's strengths.
Everywhere you turn, the Tulsa community is full of smart ideas, exciting initiatives and caring people working for a healthier community. But with so many different groups, focuses and locations, it's sometimes hard to see the big picture. We don't always know what others are doing–or needing–to make the biggest impact. Pathways to Health is blazing a new trail toward greater collaboration and outcomes.
Pathways to Health (P2H) is an engaging round table of health initiatives for our community. It brings together member agencies, institutions, businesses, foundations, and other community-health stakeholders to share ideas, increase synergies and complement each other's strengths.
We've conducted and gathered extensive grassroots level research on our community's unique health concerns and needs. From healthy lifestyle choices and nutrition to crime prevention and public safety, we put powerful data in your hands. It's a valuable advantage for better grant writing, decision making and resource allocation.
For more information or to be a part of P2H, visit www.pathwaystohealthtulsa.org or email info@pathwaystohealthtulsa.org.


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The Bridge Retail & F&B Mall
FOR LIMITED TIME ONLY! 42 Units Available!
The Bridge Mall Level 1 Retail Shops & Restaurants from under US $175K!
CHECK IT OUT NOW! CLICK HERE
The launched date of Bridge Retail Mall has been a successful one. Being able to sold out a total of 93% – the new development has received positive responsive worldwide. You have the opportunity to grab the unit of your choice for the last chance before the whole project is sold out.
Probably one of the best investment products in the market with relatively low risk and high stable return, The Bridge Cambodia By Oxley freehold retail and food & beverage units by Singapore-based developer Oxley Holdings have received overwhelming response internationally, selling near to 70% for both second and third floors in less than 6 months. Currently the retail mall is only exclusively selling in Oxley home-ground of Singapore, but not to worry for interested international buyers, we have very simple and hassle free procedures in place to facilitate in the purchase.
The Bridge Retail Mall is located at the very heart of Phnom Penh, the capital city of Cambodia, an emerging market having a 7% year-on-year growth. With it's superb location and the city's lack of full-fledged retail malls, such commercial spaces are very sought-after. Once completed, the management of the mall will be undertaken by the developer's appointed partner Metro Global which has vast experience in commercial property management , hence further ensuring favorable tenant mix and performance. This is the reason why the current sales package includes guaranteed rental returns of up to 70%!
Guaranteed Rental Returns of 6% nett p.a. for first 5 years and 8% nett p.a. for second 5 years, total up to 70% in 10 years!
Rare Freehold Strata Titled Retail Space & F&B units located in Prime Central Phnom Penh Upcoming Shopping and Tourism District
First Mover's Advantage as it is the first development with retail space for sale
High Human traffic from Soho and Apartments above as well as from patrons in the vicinity such as Nagaworld Casino- Hotel, Sofitel, Toyoko Inn, and upcoming Shangri La Hotel
Investment Flexibility with Various Unit Sizes for Combination catering to investors looking at combining multiple units
Low Entry Level for foreigners with affordable prices
Easy Exit Strategy with No Capital Gain Tax / Seller Stamp Duty and minimum holding period
Hassle-Free Option as the units are managed by a Mall Operator Metro Global, enhancing the tenant mix and mall performance
Deferred Payment Scheme with low upfront payment of 30% and balance to be paid only upon completion in 2018
Renowned Singapore Developer listed publicly in Singapore Stock Exchange (SGX)
One of The Fastest Growing Economy in ASEAN with High & Fast GDP Growth year on year
Prices of the Freehold commercial units are starting from under US$175,000.
For Developer's special discount and to find out more about other discounts structure, please click below to learn more:
Subscribe Now and be Updated to our Hot Deals and offers!
The Bridge SOHO
The Bridge SOHO (Small Office Home Office) is an unique and first of a kind concept in Phnom Penh, Cambodia. With Cambodia's rapid growth in the recent years as well as its openness to foreign investors, many enterprises and start-ups are seizing the opportunities to have a foothold in this country. The Bridge SOHO comes as a perfect product for business owners as it is conveniently located at the heart of the city centre and its magnificent architectural facade will be the new landmark of the city, boosting these businesses brand awareness too. Its flexibility to combine various units of different sizes for bigger companies as well as its high 3.6m ceiling height as a loft home office for smaller companies or individuals have attracted many investors to invest in our SOHO units.
Guaranteed Rental Returns of 6% gross p.a. for first 3 years total to 18% !
Potential Rental Returns of 7% gross p.a. for next 3 years at developer's option
Rare Freehold Strata Titled SOHO space located in one of Phnom Penh Business District
Conveniently Located at the heart of city centre and with retail mall right at doorstep, offering various options for food or business purposes
Investment Flexibility with Various Unit Sizes for Combination catering to small to big companies
Deferred Payment Scheme with low upfront payment of 50% (in stages) and balance to be paid only upon completion in 2018
Prices of the Freehold SOHO units are (FULLY SOLD!!!)
The Bridge Cambodia Concept & Design
The Bridge Cambodia is a freehold, mixed development that consists of two skyscraper towers of 45 storey high soaring up from a retail podium on a freehold land plot that's approximately 110,000 sqft. The two towers are linked by 2 sky bridges, connecting residents to provisions such as round-the-clock security, swimming pool, gymnasium, playground and clubhouse. The project is a testament that the economy of the city has reached new heights, at the same time quenching the need of the masses for quality residential, commercial and retail real estate provisions within the burgeoning city. This mega development has a total of 2355 units to offer, comprising a diversity of approximately 762 private luxry condominium units and penthouses, 630 commercial units and small offices, and 963 "home offices" that is similar to the small-office-home-office (SoHo) concept.
The Bridge Cambodia Location
The Bridge Cambodia is located at the southern Phnom Penh city, at the waterfronting part by the Bassac river, in the Tonle Bassac commune. This strategic location near the Australian embassy gives it a 360 degrees panoramic view of the waterway, Diamond Island and the Phnom Penh city skyline. Preah Sihanouk Boulevard is also a mere 2 minutes away.
The Bridge Cambodia By Oxley Construction Progress
The Bridge Cambodia By Oxley Phnom Penh Surrounding (Front/North view)
The Bridge Cambodia By Oxley Phnom Penh Surrounding (Back/South view)
The Bridge Cambodia By Oxley Phnom Penh Panoramic Surrounding View
The New Phnom Pehn
The Bridge July 2017 Construction Progress
Click here to see the latest captured pictures of The Bridge.
For Latest update of the project and details, please register below to find out more:
The Bridge Oxley is jointly developed by two prominent property developers – Singapore-based Oxley and Cambodia-based Worldbridge Land. One of the key formulas of success in this partnership is incorporating traditional Khmer architectural themes while adhering to Singapore's quality in building standards.


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Jewsei Lwowitsch Zeitlin (, wiss. Transliteration ; * 1948 in Omsk/Sibirien) ist ein russischer Literaturwissenschaftler und Schriftsteller.

Leben
Zeitlin studierte Journalistik und russische Literatur. Er war Hochschullehrer und verbrachte viele Jahre auf Reisen, um das Leben kirgisischer Dorfbewohner, sibirischer Schamanen oder der aussterbenden Nordvölker zu erforschen. 1987 begann er, die Erzählungen sowjetischer Juden aufzuzeichnen.

Für sein Buch Lange Gespräche in Erwartung eines glücklichen Todes, in dem er die Lebensgeschichten litauischer Juden dokumentiert, lebte Zeitlin zwischen 1990 und 1997 in Litauen.

Zeitlin ist Chefredakteur der religionspolitisch-kulturhistorischen Zeitung "Schalom" in Chicago, wo er seit 1996 lebt.

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Literatur (20. Jahrhundert)
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Russe
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Geboren 1948
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When I bumped into Amtrak President Joe Boardman outside Albuquerque's faux-adobe station, his wife scanned the trackside vendor tables stocked with jewelry, souvenirs and burritos.
Business is good for those New Mexico entrepreneurs when Trains No. 3 and 4, Amtrak's Southwest Chief, are on time leaving Lamy, the rural stop for Santa Fe, and Gallup in the red-cliffed Indian Country almost to Arizona. With timetables padded to help maintain the schedule, on time at Lamy and Gallup usually means early into Albuquerque in late morning going east and late afternoon chasing the sunset.
That gives passengers from Chicago, Los Angeles and 31 big and small places in between an hour or so to walk around as the trains take on fuel and change crews. At the moment the only customers are a few would-be Amtrak passengers and a handful of people off Boardman's special train, and he's wondering where both of his Southwest Chiefs are. They should have been here by now with one of them already long gone.
Railroaders operate by a minutely detailed rulebook with one unwritten rule strictly enforced: Late trains get later.
That describes Amtrak on a 2015 roundtrip from Albuquerque to Oregon by way of Los Angeles. But not in this summer of 2016.
Instead two trains covering 2,201 miles on one-way tickets reached both destinations early with only a little fuss along the way. It's how America's private passenger rail system operated into the mid 20th century and still does when everything clicks. No ailing equipment, decrepit track, disruptive passengers, dangerous weather or lame dispatching by a host railroad blew up the schedule with hours-late arrivals and missed connections.
When fire turned Albuquerque's railroad station into smoking rubble on a January night, the blame variously fell to homeless folk lighting a fire to stay warm or trouble in the electrical system of the 91-year-old building. Call it another hard-luck episode in the history of Amtrak in New Mexico.


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Baked parmesan cauliflower bites are breaded with a mixture of parmesan cheese and Italian seasoning, and served with marinara sauce for a perfect side dish or snack!
I probably spend more time than most parents thinking about why my kids prefer dinosaur chicken nuggets over Mom's cooking. Want to know my latest theory?! The breading! Yep, that crunchy, crispy breading. I see and have tasted what tempts them, and yep, it's OK. I'm not anywhere close to admitting that it's better than my cooking. BUT, I'm trying to find ways to include crispy, crunchy breading in a few of the recipes I make for the boys. Like homemade panko crusted chicken nuggets, parmesan squash rounds, and now, drumroll please, these baked parmesan cauliflower bites.
Ok so there's really a theme with MY crispy, crunchy breading. I add parmesan cheese! The method to my madness had the boys putting these parmesan cauliflower bites in their mouths [Mom win] and I'm pretty sure I saw one toddler swallow a few and another asked me for seconds [second Mom win].
Along with the parm + breadcrumbs mixture, I served these parmesan cauliflower bites with pasta and extra marinara for dipping. Think your kids aren't a fan of veggies? Throw some parmesan cheese and breadcrumbs on top and see what happens! And if not? Serve them alongside dinosaur nuggets… that sometimes does the trick here too!
Preheat oven to 400. Add breadcrumbs and cheese to a large bowl and mix together.
Dip cauliflower pieces in egg, then roll in bread crumbs. Place on a non-stick baking sheet or a baking sheet lined with parchment paper. Drizzle olive oil over the top of the cauliflower before baking to prevent breadcrumbs from drying out.
Bake for about 20-25 minutes or until coating is golden brown and crunchy. Serve with marinara sauce.
Do your kids love breading as much as mine?! Next time I'm trying this recipe with panko breadcrumbs because I think they'll be even crunchier! Manja my friends!
Loved the parmesan cauliflower bites.
These are amazing-my 8-year daughter could eat them all as her main course. Thank you!!


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Time to Migrate South
There are two options for northern hemisphere paragliders at this time of year. Put on a pair of skis or head south. But with so many options, it's hard to know where to choose. With the help of Cross Country magazine's Ed Ewing, we select five of the bes
Where: Bright, Victoria, Australia
Why: Perfect whether you want to go cross country or just soar above the tree-clad valleys. And although we love hiking, the car accessible launch site of Mystic is great too. Add friendly locals, good wine; you get the idea.
When: October to April
Expert view: "It's a good Red Bull X-Alps training ground when the northern hemisphere is frozen solid," says Ewing. "As well as XC flying, the surrounding area has seen a recent surge in hike-and-fly interest. Many of the higher peaks stretch up above the treeline making landing and re-launch possible.
Where: Kerio Valley, Kenya
Why: Kenya's Great Rift Valley is a well known wonder, attracting thousands of visitors every year. That escarpment also offers incredible flying possibilities for the adventurous, especially those seeking out and back long-distance flights.
When: December to February.
Expert view: "The Elgeyo Escarpment forms part of the western wall of Africa's Great Rift Valley and overlooks the 80km-long Kerio Valley 1,000m below. It is a perfect flying ridge."
Where: Wanaka, New Zealand
Why: It's not just the flying that's awesome in Wanaka, it's a true adventure playground with fantastic climbing, mountain biking and kayaking on the doorstep. Treble Cone, Wanaka, on the South Island, is one of the best cross-country sites in the country, offering spectacular flights around the spectacular Mt Aspiring (3,033m).
When: January to March
Expert view: "New Zealand has fantastic flying sites and something to offer every pilot. It's also classic Red Bull X-Alps training terrain."
Where: Roldanillo, Colombia
Why: It's home to fantastic flying in a great part of the world. Roldanillo is the best known site and has hosted the world championships. Typical flights see you fly along the hills, cross the valley, fly more hills, and then make your way home again.
When: December to February
Expert view: "The Cauca Valley runs from the city of Cali in the south, to Medellin 400km further north. In the lower half it is flat, cultivated, and dotted with towns and villages. The result is one of the best flying areas in South America."
Where: Porterville, South Africa
Why: It's perfectly positioned for big distance flights. The main launch at Dasklip Pass sets you up perfectly on a 100km west-facing escarpment from which great out-and-returns can be made with relative ease.
When: November to March.
Expert view: "This is one of the planet's flatland nirvanas and arguably South Africa's best known free-flying location."
Find more ideas at Cross Country's Travel Guide.
Follow us on Facebook and Instagram for more great stories!
Photos © Kolesky / Nikon / Red Bull Content Pool, © Camilo Rozo / Red Bull Content Pool, © John Stapels / Red Bull Content Pool
From Mountains to the Sea
Winter Flying


The foundations for a building in Dallas are different than in Newport Beach. And that makes a difference. But one constant for Alston is quality. Alston has constructed buildings across the country. We've forged strong relationships with the subcontractors and suppliers in our communities and know who can deliver on their promises and who can't. Plus, with a distributed team, Alston can certify your construction materials are up to spec before they ship to your job site – even if they are three states away. It is what keeps us our quality standards as one of the top in the business.
We're proud of what we've built, and so are our building owners.
One of the best projects I have ever worked on. I hope that we have another opportunity to work together!
I would like to extend our appreciation and say "thank you" for the excellent job you and your team did on the construction of Belvedere Assisted Living of Merrillville. Your team's professionalism, courtesy and commitment to meeting the goals and deadlines we had certainly reflected the quality of your organization.
There are other warehouses in Frontier's future, and we can only hope we have the opportunity to work with a construction superintendent with even half the abilities of Wayne Britain. As previously noted, it has been a pleasure working with him.
Alston continually went the extra mile in communication and working with the property owner, as well as the end user of the freestanding emergency department Swedish Health System, to ensure our satisfaction with the work.
We completed the construction project both on-time and on-budget which is always the goal, but in this case the short timeline allowed very little room to spare and required clear communication and a strong working relationship at various levels.
Please know that both You and your Teams are a key part of our success and are truly valued partners.
Through every phase of the Zulily project, the Alston team demonstrated their experience, professionalism and determination to do the job "right". "We could not have been happier with the process, or the results. We have a great facility that was delivered as promised. I know this was due to the efforts of you and your team.
I would like to take this opportunity to thank you and your staff for a great job in assisting us in the design, development and tenant improvement phases of our development in TRIC. Your budgeting estimates, attention to detail, timeliness and follow-up helped make a very successful project for our tenants and our firm.
On behalf of the employees of BOS, please accept my appreciation for the excellent job Alston did to successfully execute our project, allowing us to move into our new corporate headquarters. You should all take great pride in this accomplishment.


Wow! Amazing! Do you having any diet and skincare now?
No restrictions for diet, no skincare routine. Only jojoba oil to shave and ACV spritz from time to time! How are you going?
I feel really encouraged when I look at your photos. It gives me hope.
I'm at 5.5 months now. My face is no longer red and swelling but my skin is superbly dry and flaky, I'm oozing at the back of my legs, I have elephant skin and my hands are cracked. Did this all stop at the 7th month for you?
They there, glad you find the blog useful! I can't recall exactly but I think things really started to improve around month 7 or so. I think I stopped taking so many pics around that time… The ooze stuck around for a while but slowly the skin got stronger and the elephant skin tightened up. It's a journey! Hope you're doing well today!


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Home News Featured News The late Clarissa Tan flowered in London, not in Malaysia or Singapore
The late Clarissa Tan flowered in London, not in Malaysia or Singapore
In the early hours of March 31, prize-winning freelance journalist Clarissa Tan quietly passed away aged 42, after a year and half of battling colon cancer. A Malaysian by birth, Tan studied and worked in Singapore for 20 years before moving to London to complete a Masters degree in Creative Writing at Birkbeck, University of London. She spent the last few years of her life living in London, writing TV reviews and cultural comment pieces as a staff writer for British current affairs and culture magazine The Spectator.
Tan was born in Kuala Lumpur, Malaysia, in 1972. She moved to Singapore at the age of 15 and completed her secondary and tertiary education here, before staying on as a freelance journalist for 20 years.
In 2007 her piece "The Visit" won The Spectator's Shiva Naipaul memorial prize, awarded for 'the most acute and profound observation of a culture evidently alien to the writer'. Her writing so impressed Fraser Nelson, now editor of The Spectator, that he asked her to move to London and work with the publication.
It is Nelson who now offers up the most eloquent rendering of her life, in his tribute 'Remembering Clarissa Tan, 1972-2014':
"On her desk, there is a list, headed 'advantages of my current situation'. She had found 23 upsides. This is — was — Clarissa all over. She was defined by indefatigable optimism, humanity and love of life."
Tan was a writer of remarkable breadth, and wrote for titles as varied as The Business Times (Singapore), asia! (an online blogging platform), Reader's Digest Asia and The Daily Mail (UK), amongst others. Her topics spanned the financial world, the arts, lifestyle, education, and cultural commentary, and she was also working on a novel.
However among her most moving, poignant and beautifully-written pieces are the three in The Spectator ("I am not my cancer", "This coming year, I want to live" and "The ideal death show") in which she deals with the topic of death – specifically, her own death. In "This coming year, I want to live", just a few months after she was diagnosed with cancer, she writes:
"This coming year, I resolve to do more of the things that make me feel awakened rather than dead. I'll lean into uncertainty a bit more, and see what treasures lie there. I'll try to say what I mean and mean what I say. I aspire to open my heart as much as possible to friends, and to vulnerability, and to love. I want to fashion my own rainbow, my own groovy disco ball.
"This coming year, I want to live."
As of Tuesday April 1, the top six most-read stories on The Spectator's website were all by Clarissa Tan. It is perhaps the most fitting tribute of all for an incredibly talented writer.


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Serval - MCR-2-mediated plasmid-borne polymyxin resistance most likely originates from Moraxella pluranimalium.
MCR-2-mediated plasmid-borne polymyxin resistance most likely originates from Moraxella pluranimalium.
Poirel L., Kieffer N., Fernandez-Garayzabal J.F., Vela A.I., Larpin Y., Nordmann P.


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Digital marketing strategies that get you noticed.
I came across 683 Way to Fail to Get a Job Offer, written by Mark Manson, and thought it was a refreshing change from the usual drab magazine job search advice that's become ubiquitous in the past couple of years. The article details the selection and hiring process after the author posted a job ad for his company.
They attached or linked to copies of their previous work for me to look at even though I didn't ask for it.
They custom designed their application materials to match the design of my website and even used the same font on their resume.
They built entire WordPress sites to act as their application, with separate pages for their cover letter, resume, favorite books and so on.
They included lists of errors they had already found within my articles and suggested corrections.
They came up with design and illustration ideas to accompany my current articles without me asking.
If you're creative, proactive, and a problem solver, then prove it. Send something I would want but didn't ask for. Suggest improvements I never thought of. Write something that surprises me.
1. a job search technique influenced by the practices of technology startups which uses creativity, analytical thinking, and social metrics to showcase an individual's talents and gain exposure.
Hi. I'm a digital marketing professional that uses classic marketing strategies, behavioural psychology, and design to create websites and online campaigns that sell more stuff. Learn more.


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Home /NHL
NHL: 5 Players Most Likely to Win the Selke Award
by Trent Reinsmith | More Articles: NHL
Maddie Meyer/Getty Images
The Frank J. Selke Trophy is awarded at the end of each NHL regular season. The award, voted on by members of the Professional Hockey Writers' Association (PHWA), is given to the best defensive forward in the NHL. The trophy, which has been awarded since the end of the 1977-78 NHL season, is named after Frank J. Selke, former general manager of the Montreal Canadiens and Toronto Maple Leafs.
The first player to win the award was Bob Gainey of the Montreal Canadiens. Gainey, inducted into the Hockey Hall of Fame in 1992, won the trophy in each of the first four years it was presented. He is the only player to win the Selke four times, however, four players have won the Selke three times. Two of those players are retired (Guy Carbonneau and Jere Lehtinen), while Pavel Datsyuk of the Detroit Red Wings and Patrice Bergeron of the Boston Bruins represent the two active three-time winners. Datsyuk won the award at the end of the 2008, 2009, and 2010 seasons, while Bergeron won his Selkes in 2012, 2014, and 2015.
PHWA members vote on the Selke by selecting their top five players and awarding them points based on a 10-7-5-3-1 point system. Last year Bergeron won out over second place finisher, Jonathan Toews of the Chicago Blackhawks, by just 32 points.
Will Bergeron join Gainey as a four-time winner? Will Toews win his second Selke or will a first-time winner break through this season? Read on to find out who will be in the running for the Selke at the end of 2015-16 NHL season.
5. David Backes
Minas Panagiotakis/Getty Images
David Backes, the veteran center for the St. Louis Blues, always seems to be in the running for the Selke. His name first appeared in the voting in 2009-10, when he finished 49th with a single fourth place vote. By the next season, Backes had climbed to seventh. Since then he has never finished out of the top five in voting.
Backes averages just under 20 minutes of ice time per game. He is one of the best two-way centers in the game today, and his shutdown role doesn't keep him off the scoresheet. He has scored more than 50 points in each of the last 82 game seasons. Another plus for Backes is that he rarely misses games, notching only two absences last season.
4. Jonathan Toews
The only time that Chicago Blackhawks' Jonathan Toews failed to garner a Selke vote was his rookie season. In his sophomore year, Toews finished 17th in voting. Since then he has never finished lower than sixth, winning the award in 2012-13. He was runner-up last season.
Toews has one the highest hockey IQs in the game today. He is responsible at both ends of the ice, and a beast in the face-off circle. Toews also regularly ranks among the best centers as far as his plus/minus ranking is concerned, and, as captain of the Blackhawks, is one of the best leaders in the NHL.
3. Max Pacioretty
If early season play is any indication, 2015-16 will be the year Max Pacioretty makes the leap into the top five in Selke voting. Last season was the first time the Montreal Canadiens left wing received any votes for the trophy, finishing in sixth place.
Pacioretty played in a career-high 80 games last year, tying Nikita Kucherov of the Tampa Bay Lightning for first in plus/minus ranking with a +38. In addition, he had a career high in average time on ice with 19:24 per game, takeaways with 43, and points with 67 (37G, 30A). Pacioretty has come out of the gate hot this season and is on pace for a career high in points; he's also among the league leaders in plus/minus.
2. Patrice Bergeron
It's no surprise to see the Boston Bruins' Patrice Bergeron on this list. The 30-year-old center has already won the award three times (2011-12, 2013-14, and 21014-15) and finished as runner-up once. In the last six seasons, Bergeron has not finished lower than fifth in Selke voting.
Bergeron is one of the best face-off men in the game, winning a whopping 60.2% of his face-offs last year to lead the league. Bergeron is a player the Bruins can throw out in any situation. Even when he is matched up against the opposition's top offensive line, which is more often than not, Bergeron can and will produce.
1. Anze Kopitar
Jure Makovec/Getty Images
Anze Kopitar of the Los Angeles Kings has never won a Selke. He's finished as high as second (2013-14) and has been in the top 10 each year since the 2010-11 season. So, 2015-16 may be his breakthrough year.
Kopitar usually plays more than 20 minutes per game and can be counted on to score more than 60 points per season. His face-off winning percentage has been above 52% in each of the last four seasons, and he rarely takes penalties. Last season, Kopitar led all NHL forwards in SAT (shot attempts differential), with the Kings logging 363 more shot attempts than the opposition when Kopitar was on the ice. Early this season, Kopitar is once again among the leaders in SAT.
The one factor that may lock up the award for Kopitar: if the Kings make the playoffs and the Bruins do not.


With Arabella Trefoil, Trollope created one of his most formidable characters.
Arabella's determination to find a rich husband is at the heart of The American Senator, and her character is one of Trollope's most famous and vivid creations.
Tall, blonde, beautiful, stately, Arabella is thirty and has been on the marital market for nearly ten years, held there by her grasping mother, Lady Augustus.
She is engaged to the stiff civil service diplomat John Morton who becomes the heir to Bragton Hall, an estate of some substance in the Midlands.
Its sorry state of repair instills doubts both in Arabella and her mealy-mouthed mother; doubts compounded by the wealthy Lord Rufford of Rufford Hall, who is altogether a more enticing prospect.
Arabella does not expect love: indeed, it is debatable whether she ever did. Faced with Lord Rufford's considerable wealth, and in the presence of her fiancé, she goes after the aristocrat, ultimately stumbling at the last hurdle.
Arabella is a magnificently unsentimental anti-heroine. She is not a keen sportswoman but, in pursuit of the huntsman Rufford, is quite the huntress, plotting out and adapting her strategy over the course of several months in an attempt to snare her prey.
There is no sentiment whatever about Arabella, just levelheaded practicality supported by a dash of ruthlessness.
The difficulties which Arabella faces lie in her own brutal self-awareness of the facts of life as she perceives them: she has no friends, everyone knows she is actively seeking a fortune, and she makes little pretense about it.
Arabella Trefoil is an endlessly intriguing character and one of the most memorable ever created.


Here's a shot from a party during the filming of Mosquito Coast (released 1986). The twins with Barry Bowen.
This article was done for the December 1986 issue of American Film for the release of "The Mosquito Coast" and was written by Digby Diehl.
Gracey Rock, Belize, 12:30 A.M. Gracey Rock was nothing more than a wide spot on the Sibun River - unfarmed raw jungle - until it was transformed into the community of Jeronimo for the filming of Paul Theroux's 1982 novel, The Mosquito Coast. The set looks like an army encampment dumped in the Central American jungle, and in this hotbed of political unrest, the resemblance is unnerving.
In the middle of the jungle, looking like a foreboding Mayan monolith, sits a juggernaut named "Fat Boy". Built by a latter-day Swiss Family Robinson, this huge ice house symbolizes the technological hubris and American ingenuity they brought to the experiment of starting life over, freed from the decadence and disappointments of modern civilization. Fat Boy is eerily illuminated by large searchlights beaming down from the palm trees, but beyond the lighted perimeter of the set, the jungle is black and intense. The sounds of wild monkeys and tropical birds fill the hot, humid air. The crew moves around under the lights, making sure all is ready for a climactic scene.
Paul Theroux's novel chronicles the saga of freethinker and all-purpose handyman Allie Fox (played by Harrison Ford in the film), whose frustration and disgust with life in America leads him to pack up his family and create a garden of Eden in the jungle. Producer Jerry Hellman acquired the rights to the book when it was first published at least in part because he identified with Fox's independence, his anger at modern life. "I understood what he was all about," Hellman says. "His reaction - to get the hell out of here - is a legitimate reaction to modern life, not the only one, but an appropriate one."
When I first read the book, I loved the bizarre aspects of it," says director Peter Weir, his ever-present tape deck spewing forth Beethoven's Fifth into the tropical Belize air. Weir is dressed for the jungle in safari jacket and T-shirt and takes an obvious delight in his romantic surroundings. Sweating profusely, he never appears uncomfortable, but basks in both the literal and creative heat.
As we drive over the main highway from Belize City to Guatemala en route to the set, Hellman waxes enthusiastic about the project. The two of us bounce along in the back seat with a tape recorder. "A director like Peter never has a 'finished' script," says Hellman. "Most executives in the business think in terms of script. they want to sit and fiddle with 'the script' until they get it right, and they believe they will know what 'right' is. It's foolhardy to think that there is a finished script and then you go out and shoot it precisely as it's written. That's just not the reality. The reality is an ongoing process."
Weir divides the writing of a film into three parts: the conception (the screenplay), the realization (the shooting), and the shaping (the cutting). "There's a lot of overemphasis on the original screenplay," he says. "What you really want is the conception, the clarity and beauty of the initial idea. Then the middle period, the actual shooting, is the struggle to realize the idea, given the enormous problem of logistics. The third period, the cutting, is the last chance to write the movie into decent shape. Few outside the cutting room understand that film editing is part of the writing process. It's always assumed to be a mechanical function, but it is, in fact, writing using pieces of celluloid."
"Eisenstein said that over and over. And I've found that people who best understand that editing is writing are those who edit film and videotape for news programs," he continues. "I've watched television-news editors fictionalize hard news - I learned more about cutting from them then from anybody. You can take footage of an interview with a Druse militiaman in Beirut and make him anything you want to. You can make him an idiot. You can make him a proud hero. You can make him cruel. This forever destroyed the concept of 'documentary' for me. It's the greatest fiction of all."
Directors vary widely in their approach to the filmmaking process; Weir has a reputation as one of the most "open" directors in the business. His method of working would appear to be seat-of-the-pants, if not downright haphazard.
Weir's inspiration for his interpretation of Mosquito Coast comes, he says, from the classics, especially Shakespeare and from the opera. "It's taken me a long time to understand where the power was coming from in this story," he explains. In the background, Wagner's Die Walkure is the selection on his tape deck. "There's a tremendous amount of emotion in the story. Unless it is harnessed into some sort of framework by me, I'll be stirring the audience up and they'll wander out feeling uncomfortable because they were moved, but without understanding what to do with their emotion. I think I've got the framework in this operatic feeling. In opera, many times you start with everything wonderful, the songs bright and positive, and then the complexities arise and you end with tragedy."
In the living room of the house Weir occupies in Belize (right next door to the production office), he has ample evidence of his thematic motifs spread out across every available surface. On a large bulletin board he keeps postcards, pages from magazines, and other items that embody the look or the visual impression he wants to give various portions of the film. "A letter sent to me, a snapshot of a child in a village, a pressed flower, a match box, colors... they all have a meaning. It's a question of texture, a kind of mosaic of inspirations. If you look carefully, you'll see that almost every key scene is represented by something or other. That's how I've always done my films. I like to have these things around me and let them have their influence as they might."
Weir realizes that his approach is not without danger. "I like to open the door to chance. That implies enormous risks. You presume on the muse visiting you, but at the same time you don't count on it. Driving to work you see street scenes - a face, a hat, a detail - that you often end up putting into the film that very day. I saw a man with a plastic bag on his head with just the face part cut out and a straw hat on top of that and said, 'Let's do that.' But it won't help the drama itself. You've got to have good acting and good thinking."
From Harrison Ford , Weir says he gets both. During the filming of Witness, the actor and director established an extraordinary partnership, Ford, the logical man and self-described "technical" actor, is the perfect complement to Weir, the improvisational visionary. "I supply him with something, he supplies me with something," Ford says. "We both benefit from the exchange. Peter has a vision and it's not always articulatable, if that's a word. I'm a person who calls for logic and even a plodding kind of determination to have all the cards on the table. I'm the assistant storyteller."
Ford found the eccentric character of Allie Fox a welcome change from heroic roles. One night, while waiting for the gigantic generators from Miami to be repaired so that shooting could resume, we sit in his air-conditioned motor home/dressing room talking late. He is exhausted, at the end of a long, hard location shoot, and he is beginning to take on the character of Allie Fox in earnest. "I had none of the difficulties that other people had expressed with the character being too irascible, too unconventional," he says. "I found him more often right than wrong in what he was saying. There is also the complexity of the family story, the relationship between a father and son and between a husband and wife. There is humor and pathos, a real range from antic comedy to gut-wrenching stuff. The simple exercise of emotion is something that people don't get very much. At the moment, most films depend more on kinetics for their effect than on having any emotional resonance."
Ford also welcomed the opportunity to work again with Weir, who is gradually gathering his own "reportory company" of crew and actors. And small wonder - Weir is known for running a happy ship. The crew in Belize is a pastiche of Aussies, Brits, and Yanks that number about 150. And key personnel such as director of photography John Seale and film editor Thom Noble, are veterans of other Weir films. "This crew is a combination of people from Witness who I found exceptional, mixed with the old crew that go back to my early films in Australia.," says Weir. "Here on location, we have that kind of intimacy that only comes on a set. It doesn't exist in peacetime, you might say. On location in the jungle you don't have the nine-to-five mentality that you have in city shooting. I like the concentration that results from everybody being at hand and from the ideas that abound in the surroundings. The atmosphere of the film is within the setting all around you. You disappear into the film." He gestures toward the crowded bar of the Villa Hotel, where the Mosquito Coast company is drinking, dancing, and laughing with the locals. Weir frequently holds court there, staying late into the night after a day's shooting. In the background, the music of the Turtle Shell Band, an Afro-Caribbean group from the Belizean coast, issues forth from Weir's tape deck.
"Belize is the Mosquito Coast," Hellman says. Although Theroux was unaware of it at the time he was writing the story, the fictional Allie Fox turns out to have a number of factual counterparts. "Central America is full of Allie Foxes," says Weir. "I've heard of four of them since I've been here in Belize. Many of them came down here in the late sixties. Belize is one of the last places in the world where you'll find the drifters, the travelers. No one is down here just on a holiday. If someone says they're here on vacation, you know they're CIA or they're drugs."
For the people who live in Belize, however, the filming of The Mosquito Coast is the biggest story that's come their way in a long while. The making of this movie was practically all I heard anyone talking about from the moment I arrived at the rustic, dilapidated airport. Whether I was in a fishing boat or a taxicab, the natives quizzed me about the moviemaking. No wonder they were fascinated: In a tiny (population 148,000) agricultural country, the filming employed about three hundred local residents, spent seven or eight million dollars in foreign exchange, and made executive producer Saul Zaentz, for a time, the third largest industry in Belize.
Despite Belizean government cooperation, the logistics of the production have been awesome. The company had to build roads into the jungle, support an entire small hospital for emergency help, coordinate with fifty local contractors who were accustomed to a leisurely Caribbean pace of life, and stay out of the myriad political skirmishes among the Belizeans, Guatemalans, Salvadoran refugees, and native Indians. In Mexico City, a convoy of catering trucks met up with the motor homes (to be used as dressing rooms) and portable honey wagons, and meandered down the so-called highways of Mexico and Central America to Belize. Shiploads of other trucks and equipment, including three huge electrical generators for night shooting, arrived from Miami. And an exhausted team of couriers shuttled film back and forth from a Miami lab for dailies. (The local airline, TACA, was quickly dubbed "Take A Chance Airline.") "The Miami connection has been a godsend," says production coordinator Judi Bunn. "You have no idea how crazy people get when they can't buy the right American shampoo or deodorant. It's wonderful to have the New York Times brought in on Sunday. Of course," she adds with an emphatic British accent, "I had to wait until Tuesday for the London Times."
At the main jungle location in Gracey Rock, a bulldozer begins clearing an area where the main house for Allie Fox and his family will be built. Ninety feet into an anticipated one-hundred-foot space, the bulldozer hits a twenty-foot-high mound of rock. The Mosquito Coast has made an archaeological discovery: an unrecorded Mayan site, probably a minor temple or residential building. Weir modifies their set location plans, but is using the Mayan temple mound as a camera platform for the final Fat Boy sequence.
At 1:45 A.M., first assistant director Mark Egerton signals that all is finally ready for that scene to begin. Harrison Ford, looking quite deranged in wire-rim glasses and slicked-down hair, is sprayed with "sweat". Jerry Hellman swats a mosquito and sprays himself with Deep Woods Off. Peter Weir, grinning puckishly, gets a laugh from the assembled cast and crew as his tape deck blares out Gladys Knight's "I Heard It Through the Grapevine." He greets them by saying, "OK, ladies and gentlemen. Welcome to the late night show. Now, let's do it!" Shortly thereafter, red horns of fire sprout from Fat Boy's head and flames belch forth from its eyes and nose. Civilization has its revenge on Fox and his family as the technological monster rocks the jungle in a series of violent explosions and destroys their dream of Eden.
"The Mosquito Coast" is a film I think very highly of even though it is not (in my opinion) your typical Hollywood fare. In fact, I think it is a ways off the beaten track, so for filmgoers who like something more out-of-the-way, this is a pretty good film to partake of. It is, I think, a film with a "message" in it, and while this is certainly nothing new in movies, I think part of the charm of the picture is that the message is very succintly understated (you do have to think about it). It is certainly well-acted by all the performers in it-- Harrison Ford, Helen Mirren, and River Phoenix deserve special praise for giving very fine and probing performances to their characers (all three are very good in virtually anything they appear in--yes, I know that River Phoenix is deceased and that is too bad because he might have gone on to become a truly great star and actor, had he lived), and Peter Weir's direction ("The Year of Living Dangerously", "Dead Poet's Society") is masterful--especially because I believe that the subject matter of the story was not easy to convey. It is also beautifully photographed-- especially the sequences out in Mosquitia, which is along the Carribbean coast in Central America. But let the viewer be warned: This story is a tragedy, and the end of it does have a certain pathos to it. Essentially, it is a uniquely American story, even though it happens largely outside the U.S. It surrounds the Harrison Ford character, and is essentially a character-study of this strange and unique man and his angry dilemma, and his subsequent "fall from grace". I believe the "study" of the Ford character in this film is comparable to the roll that Humphrey Bogart had in "Treasure of the Sierra Madre" in that it is also a look at a person who is driven to great desperation not only by his own desires and weaknesses, but also by his own vanity. A must see!