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Is 'dark DNA' lurking as 'missing' mystery force in animal evolution?
Adam Hargreaves | October 5, 2017
DNA sequencing technology is helping scientists unravel questions that humans have been asking about animals for centuries. By mapping out animal genomes, we now have a better idea of how the giraffe got its huge neck and why snakes are so long. Genome sequencing allows us to compare and contrast the DNA of different animals and work out how they evolved in their own unique ways.
But in some cases we're faced with a mystery. Some animal genomes seem to be missing certain genes, ones that appear in other similar species and must be present to keep the animals alive. These apparently missing genes have been dubbed "dark DNA". And its existence could change the way we think about evolution.
My colleagues and I first encountered this phenomenon when sequencing the genome of the sand rat (Psammomys obesus), a species of gerbil that lives in deserts. In particular we wanted to study the gerbil's genes related to the production of insulin, to understand why this animal is particularly susceptible to type 2 diabetes.
But when we looked for a gene called Pdx1 that controls the secretion of insulin, we found it was missing, as were 87 other genes surrounding it. Some of these missing genes, including Pdx1, are essential and without them an animal cannot survive. So where are they?
The first clue was that, in several of the sand rat's body tissues, we found the chemical products that the instructions from the "missing" genes would create. This would only be possible if the genes were present somewhere in the genome, indicating that they weren't really missing but just hidden.
The DNA sequences of these genes are very rich in G and C molecules, two of the four "base" molecules that make up DNA. We know GC-rich sequences cause problems for certain DNA-sequencing technologies. This makes it more likely that the genes we were looking for were hard to detect rather than missing. For this reason, we call the hidden sequence "dark DNA" as a reference to dark matter, the stuff that we think makes up about 25 percent of the universe but that we can't actually detect.
By studying the sand rat genome further, we found that one part of it in particular had many more mutations than are found in other rodent genomes. All the genes within this mutation hotspot now have very GC-rich DNA, and have mutated to such a degree that they are hard to detect using standard methods. Excessive mutation will often stop a gene from working, yet somehow the sand rat's genes manage to still fulfil their roles despite radical change to the DNA sequence. This is a very difficult task for genes. It's like winning Countdown using only vowels.
This kind of dark DNA has previously been found in birds. Scientists have found that 274 genes are "missing" from currently sequenced bird genomes. These include the gene for leptin (a hormone that regulates energy balance), which scientists have been unable to find for many years. Once again, these genes have a very high GC content and their products are found in the birds' body tissues, even though the genes appear to be missing from the genome sequences.
Related article: Molecular clocks rewriting the story of human evolution
Shedding light on dark DNA
Most textbook definitions of evolution state that it occurs in two stages: mutation followed by natural selection. DNA mutation is a common and continuous process, and occurs completely at random. Natural selection then acts to determine whether mutations are kept and passed on or not, usually depending on whether they result in higher reproductive success. In short, mutation creates the variation in an organism's DNA, natural selection decides whether it stays or if it goes, and so biases the direction of evolution.
But hotspots of high mutation within a genome mean genes in certain locations have a higher chance of mutating than others. This means that such hotspots could be an underappreciated mechanism that could also bias the direction of evolution, meaning natural selection may not be the sole driving force.
So far, dark DNA seems to be present in two very diverse and distinct types of animal. But it's still not clear how widespread it could be. Could all animal genomes contain dark DNA and, if not, what makes gerbils and birds so unique? The most exciting puzzle to solve will be working out what effect dark DNA has had on animal evolution.
In the example of the sand rat, the mutation hotspot may have made the animal's adaptation to desert life possible. But on the other hand, the mutation may have occurred so quickly that natural selection hasn't been able to act fast enough to remove anything detrimental in the DNA. If true, this would mean that the detrimental mutations could prevent the sand rat from surviving outside its current desert environment.
The discovery of such a weird phenomenon certainly raises questions about how genomes evolve, and what could have been missed from existing genome sequencing projects. Perhaps we need to go back and take a closer look.
Adam Hargreaves is a Postdoctoral Research Fellow at the University of Oxford. His research involves how changes in the genome and alterations in gene regulation can give rise to innovations, and how these relate to evolutionary adaptation. Follow him on Twitter @AdamHargreaves5
A version of this article was originally published on the Conversation's website as "Introducing 'dark DNA' – the phenomenon that could change how we think about evolution" and has been republished here with permission.
The GLP featured this article to reflect the diversity of news, opinion and analysis. The viewpoint is the author's own. The GLP's goal is to stimulate constructive discourse on challenging science issues.
39 biotech experts' open letter protests anti-GMO activist Vandana Shiva's 'anti-science' talks at Stanford and UC Santa Cruz
Viewpoint: After years of bashing agriculture and GMOs, Chipotle reverses course with 'Cultivate the Future of Farming' campaign
Psychedelics have 'extraordinarily potent' anti-inflammatory power. Is there a place for them in mainstream medicine?
Artificial wombs could create seismic shift in the debate over abortion, reproductive rights
Bayer close to settling more than 75,000 glyphosate-cancer lawsuits, mediator says
Do the MAOA and CDH13 'human warrior genes' make violent criminals—and what should society do?
How Freddie Mercury got his voice: It wasn't his teeth
Does organic mean 'pesticide free'? 5 things to know about the USDA organic label
Viewpoint: GMO crops should become a bigger part of the food system if we want a sustainable society
Epigenetics Around the Web: Trump isn't affecting human evolution and organic produce isn't helping your sperm
Biotechnology timeline: Humans have manipulated genes since the 'dawn of civilization'
How our autistic ancestors helped shape human evolution
Evolution and war: The 'deep roots' theory of human violence
Farming & Food
Facts about pesticides and pollinators
Talking Biotech
Explore the future of food and biotech
Analyzing the critics shaping the debate
News on human & agricultural genetics and biotechnology delivered to your inbox.
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July's Playlist… what a lot to look forward to!
Something old, something new, and, as I can't seem to wean myself off the folk, a fair bit of fiddle! Thanks to Rebecca Landman, my faithful UK listener, for introducing me to Laura Marling, and also to our friends the Neilds in Worthing, UK, who shared Gotye with me this month – no, I'm not … More July's Playlist… what a lot to look forward to!
Leave a comment July's Playlist… what a lot to look forward to!


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« Climate Change May Slam the Caribbean | Home | LAC Environmental Trivia, Revisited »
Is Vaccination for Rotavirus Gastroenteritis Cost-Effective in LAC?
By Keith R | June 19, 2008
Topics: Health Issues, Renewable Sources | No Comments »
A recent issue of the Pan American Journal of Public Health, the scientific journal published by the Pan American Health Organization (PAHO), contained an article* that looks at the cost-effectiveness of universal rotavirus vaccination program in Brazil among children age five or younger. Brazil introduced such a vaccination program in March 2006 on purely public health grounds; this analysis confirms that the decision also made sense in economic terms.
The country study further seems to confirm the findings of a broader multi-country cost-effectiveness analysis published in the same journal last year (see below).
Rotavirus infection is the single most important cause of gastroenteritis, often leading to severe diarrhea and dehydration in children, sometimes resulting in hospitalization and even death. A recent analysis of eight diverse Latin American and Caribbean (LAC) nations suggested that for every 1,000 children born in those countries in 2003, rotavirus gastroenteritis resulted in an average 246 outpatient visits, 24 hospitalizations, 0.6 deaths and US$7,971 in direct medical costs during the first five years of life.
Since rotavirus infection persists as a problem in both developed and developing countries, public health experts think that merely improving sanitation will not suffice — that universal vaccination may be called for. [The World Health Organization (WHO) has actually advocated this.]
The Brazilian Case
The Brazilian study looked at a hypothetical annual cohort of about 3,300,000 newborns followed over five years, and possible clinical and economic impacts of rotavirus infection with and without routine vaccination. Probabilities and units costs were derived from national administrative data and published research.
The vaccination program was estimated to prevent approximately 1,735,351 (54%) of the 3,210,361 cases of rotavirus gastroenteritis and 703 (75%) of 933 rotavirus-associated deaths during the 5-year period. At a vaccine price of 18.6 Brazilian reais (R$) per dose, this program would cost R$121,673,966 and would save R$38,536,514 in direct costs to the public healthcare system and R$71,778,377 in direct and indirect costs to society. The program was estimated to cost R$1,028 and R$1,713 per life-years saved (LYS) from the societal and healthcare system perspectives, respectively.
The authors caution that these calculations may even underestimate the savings. The model does not account for reinfection rates (reinfection incidence is about 1.2 per child in Brazil), and it ignores (numerous) milder cases that do not require medical treatment. Together they may add up to significant costs from the societal perspective that are not accounted for.
Vaccine Price May Be Key
The study finds that changes in vaccine efficacy have little impact. Changes in vaccine price, however, have a great impact: a 25% difference in price results in a 32% to 55% change in the incremental cost-effectiveness ratio (ICER). From the point of view of society, a 50% decrease in price makes the Vaccination Program strategy cost saving. The authors note that, since the study was conducted, the currency conversion rate between Brazilian real and US dollars changed considerably, resulting in a 32% cost drop in local currency terms. They also noted that recent Brazilian negotiations for technology transfer agreements with vaccine manufacturers should drop prices still further.
Is the Same True for Other LAC Nations?
The Brazilian study would seem to confirm another** published in the same journal last year. Done by researchers at Emory University's Rollins School of Public Health and GlaxoSmithKline (GSK, a vaccine producer), the prior work attempted to estimate the costs, benefits and cost-effectiveness of rotavirus vaccination in eight diverse (different costs, health systems, demographics, etc.) LAC nations: Argentina, Brazil, Chile, the Dominican Republic, Honduras, Mexico, Panama and Venezuela.
The economic model used national administrative and published epidemiological evidence, country-specific cost estimates, and vaccine efficacy data. The model was applied to the first five years of life for the 2003 birth cohort in each country. The main health outcome estimated was the disability-adjusted life year (DALY), and the main summary measure was incremental cost per DALY averted. A 3% discount rate was used.
The model found that vaccination would prevent more than 65% of the medical visits, deaths and treatment costs associated with rotavirus gastroenteritis in the eight LAC nations. If a two-dose vaccine costs US$24 per course, the ICER ranged from US$269 per DALY in Honduras to US$10,656 per DALY in Chile. The report concludes that rotavirus vaccination is cost-effective for these nations, although the authors admit that not all nations will have the financial resources readily available to them to add the rotavirus vaccine to their national immunization programs.
They also noted three potentially important limitations to their study: (1) delays in the timing of routine vaccinations may mean that some roatvirus-associated events may not be avoided by a vaccination program; (2) it is not known if vaccination coverage among those children most at risk of dying from roatvirus infection is as good as that of the general populace; (2) the potential indirect protective effect of "herd immunity" for persons not vaccinated was not taken into account.
* de Soárez PC, Valentim J, Sartori AMC, Novaes HMD. Cost-effectiveness analysis of routine rotavirus vaccination in Brazil. Rev Panam Salud Publica. 2008;23(4):221–30.
** Rheingans RD, Constenla D, Antil L, Innis BL, Breuer T. Potential cost-effectiveness of vaccination for rotavirus gastroenteritis in eight Latin American and Caribbean countries. Rev Panam Salud Publica. 2007;21(4):205–16.
Is Childhood Vaccination Against Hepatitis A Cost-Effective?…
The Costs of Vaccinating and of Not Vaccinating: The Case of…
Tags: Argentina, Brazil, children, Chile, DALY, diarrhea, Dominican Republic, Emory University, gastroenteritis, GSK, herd immunity, Honduras, ICER, Mexico, OMS, OPAS, OPS, PAHO, Pan American Journal of Public Health, Panama, public health, República Dominicana, Rollins School of Public Health, rotavirus, salud pública, saneamiento, Sanitation, saude, technology transfer, vaccination, vaccines, vacunación, vacunas, Venezuela, WHO

redpajama_set_name: RedPajamaCommonCrawl


text:
Franklin Oliver Fuller
Full Name: Franklin Oliver Fuller
Date of death: August 9, 1934
H 11 Jan 9, 1917 - Dec 4, 1918 35th (1) Democrat Coldspring / San Jacinto Speaker Polk, San Jacinto
H 11 Jan 12, 1915 - Jan 9, 1917 34th Democrat Coldspring / San Jacinto Polk, San Jacinto
H 11 Jan 14, 1913 - Jan 12, 1915 33rd Democrat Coldspring / San Jacinto Polk, San Jacinto
H 19 Jan 12, 1909 - Jan 10, 1911 31st (2) Democrat Coldspring / San Jacinto Angelina, Polk, San Augustine, San Jacinto
H 19 Jan 8, 1907 - Jan 12, 1909 30th (3) (4) (5) (6) Democrat Coldspring / San Jacinto Angelina, Polk, San Augustine, San Jacinto
(1) Fuller resigned 12/4/1918. Members of the Texas Congress 1836-1845; Members of the Texas Legislature 1846-2004, 2005.
(2) Democrat; roster of members of the 31st Legislature with biographical and party information. "Year Book 1909," Number 13, May-June 1910, pp. 408-415. Bulletin (Texas Department of Agriculture), 1910.
(3) COLDSPRING, TEXAS. "Coldspring is at the junction of State Highway 150 and Farm roads 1514, 946, and 2025, sixty-five miles north of Houston in central San Jacinto County . . . in 1850 the [post office] name was changed to Cold Spring, officially respelled Coldspring in 1894." Handbook of Texas Online.
(4) Cold Springs. House Journal.
(5) Cold Spring, San Jacinto County. Members of the Texas Congress 1836-1845; Members of the Texas Legislature 1846-2004, 2005.
(6) Cold Springs. Texas Legislative Manual.
43rd Legislature, 3rd C.S., 9/19/1934, p. 241. Resolutions - Memorial.
Franklin Oliver Fuller, birth date 11/2/1873, death date 8/9/1934, biographical sketch, newspaper photo, burial in Hollywood Cemetery, Houston. Find a Grave.
FULLER, FRANKLIN OLIVER (1873-1934). Death date 8/9/1934. Handbook of Texas Online.
45th Speaker of the House of Representatives: Franklin Oliver Fuller. Photo and biographical sketch. "In 1920 he moved from Coldspring to Houston . . . " Death date 8/7/1934. Presiding Officers of the Texas Legislature, 1846-2016, 2016.
Biographical sketch and portrait, F. O. Fuller, pp. 689-691. Texas, the Country and Its Men: Historical, Biographical, Descriptive, 1918.
Occupation and religious affiliation, 34th Legislature. "Occupations of Members of Legislative House," 3/14/1915, p. 4. Galveston Daily News.
Photograph. F.O. Fuller, 35th Legislature, State Preservation Board
Photograph. F.O. Fuller, 33rd Legislature, State Preservation Board
Photograph. F.O. Fuller, 31st Legislature, State Preservation Board
Photograph. F.O. Foller, 30th Legislature, State Preservation Board
Photograph. Franklin Oliver Fuller, Presiding Officers of the Texas Legislature, 1846-2006
31st session composite photo of House members (House chamber gallery, north wall. 3W.2). State Preservation Board.
33rd session composite photo of House members (House chamber gallery, west wall. 3W.2). State Preservation Board.
34th session composite photo of House members (House chamber gallery, west wall. 3W.2). State Preservation Board.
Central Investigating Committee
Penitentiaries Subcommittee to Visit Penitentiaries
Private Corporations (Chair)
Reforms in Criminal Procedure
Liquor Traffic (Chair)
Reforms in Civil Procedure
31st 1st C.S. - 1909
Common Carriers
Examination of Comptroller's and Treasurer's Accounts
Reforms in Civil and Criminal Procedure
Forestry (Chair)
Private Corporations


text:
'use strict';
var child = require('child_process');
var conventionalChangelog = require('../');
var expect = require('chai').expect;
var shell = require('shelljs');
var through = require('through2');
var writeFileSync = require('fs').writeFileSync;

describe('presets', function() {
  describe('ember', function() {
    before(function(done) {
      shell.cd('ember');
      shell.exec('git init');
      writeFileSync('test1', '');
      child.exec('git add --all && git commit -m"Merge pull request #12001 from rwjblue/remove-with-controller\n\n[CLEANUP beta] Remove {{with}} keyword\'s controller option. Closes #1"', function() {
        writeFileSync('test2', '');
        child.exec('git add --all && git commit -m"Merge pull request #11984 from emberjs/fix-each\n\n[PERF beta] `@each` should remain a stable node for chains."', function() {
          writeFileSync('test3', '');
          child.exec('git add --all && git commit -m"Merge pull request #11970 from pixelhandler/ember-rfc-80\n\n[DOC Release] Make ArrayProxy public"', function() {
            writeFileSync('test4', '');
            child.exec('git add --all && git commit -m"Merge pull request #12010 from duggiefresh/12004-doc-array-methods\n\n[DOC release] Mark `Ember.Array` methods as public"', function() {
              writeFileSync('test5', '');
              child.exec('git add --all && git commit -m"Merge pull request #12017 from rwjblue/deprecate-render-function\n\n[BUGFIX release] Deprecate specifying `.render` to views/components."', function() {
                writeFileSync('test6', '');
                child.exec('git add --all && git commit -m"Merge pull request #11968 from jayphelps/remove-ember-views-component-block-info\n\n[FEATURE ember-views-component-block-param-info] remove feature info and unflag tests"', function() {
                  writeFileSync('test7', '');
                  child.exec('git add --all && git commit -m"Merge pull request #1000 from jayphelps/remove-ember-views-component-block-info\n\n[SECURITY CVE-2014-0013] Ensure primitive value contexts are escaped."', function() {
                    writeFileSync('test8', '');
                    shell.exec('git add --all && git commit -m"Bad commit"');
                    writeFileSync('test9', '');
                    shell.exec('git add --all && git commit -m"Merge pull request #2000000 from jayphelps/remove-ember-views-component-block-info"');

                    done();
                  });
                });
              });
            });
          });
        });
      });
    });

    after(function() {
      shell.cd('../');
    });

    it('should work if there is no semver tag', function(done) {
      conventionalChangelog({
        preset: 'ember'
      })
        .pipe(through(function(chunk) {
          chunk = chunk.toString();

          expect(chunk).to.include('[12001]');
          expect(chunk).to.include('Remove {{with}} keyword\'s controller option.');
          expect(chunk).to.include('Release');
          expect(chunk).to.include('### Bug Fixes');
          expect(chunk).to.include('### Cleanup');
          expect(chunk).to.include('### Features');
          expect(chunk).to.include('### Documentation');
          expect(chunk).to.include('### Security');

          expect(chunk).to.not.include('CLEANUP');
          expect(chunk).to.not.include('FEATURE');
          expect(chunk).to.not.include('Bad');

          done();
        }));
    });
  });
});

redpajama_set_name: RedPajamaGithub


Now warmer days are here, there's no better time to explore Crete's wonderful flora. This island's gorgeous, often unique flowers have always beguiled nature lovers. But you don't have to be an expert to appreciate these natural wonders of the landscape. April and May sees the greatest profusion of wild flowers in bloom, but March also offers a glimpse of some of Crete's finest species. You just need to know where to look, and what to look out for.
Gladiolus italicus blooms in Heraklion province in springtime.
The cheerful common daisy (Bellis perennis) popped up weeks ago, defying the chill north wind and telling us spring was around the corner. A shyer beauty – perhaps the most loved wild flower of Crete – the orchid – has already made its first dazzling appearance. With more than 60 species of orchid on Crete, some of the most beautiful like the rare endemic Ophrys mesaritica, (originally found on the Messara Plain), are blooming now. Last month the first anemones appeared, and with temperatures rising their delicate lilac, pink, purple, and deep red blooms are splashing the hillsides with colour.
Crete is home to some 2000 species of plants, of which about 10 percent grow nowhere else in the world, and the reason why Greece's largest island is a flower lover's paradise is because of the island's physical isolation. It broke away physically from the mainland of southern Europe over 5 million years ago, and its isolation and mountainous terrain created many unique eco-systems – environments where particular plant species evolved and flourished.
It's important to remember that nature's beauty is fragile in Crete. The Red Data Book of Rare and Threatened Plants of Greece (the result of the most detailed recent research on the subject) lists 67 endangered plants growing on Crete, so tread carefully on your explorations! For those wishing to know more about Crete's wonderful wild flowers there's a lovingly produced Facebook page Flowers of Crete.
With thanks to writer and administrator of Flowers of Crete, Julia Jones, for her assistance in the research for this article. All images copyright Julia Jones.
Paeonia clusii – found at high altitudes, especially in the mountains of Dikti and the Lefka Ori, the White paeonia is endemic to Crete and Karpathos.


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text:
Graduate Archer Fellowship Program Alumni Profiles
Clare Magee: "I'm deeply impressed by how committed the Archer Center is to the continued success of its alumni after the official program concludes."
Christine Duchouquette: "The most valuable lesson learned as an Archer Alumna was the impact of your voice, advocacy and money in politics."
Anthony Vincent LeClair: "There is no experience in graduate school that allows you the practical experience in policy that the Archer Center Graduate Program in Public Policy offers."
Emily K. Worland: "My Archer Fellowship experience gave me the confidence and conviction to pursue a law degree."
Ashlee Stiles: "My favorite memory of the Graduate Program in Public Policy is of the Archer Fellows standing in line on the steps of the Lincoln Memorial taking turns reciting Martin Luther King Jr's 'I have a Dream' speech."
Joanna D. Sánchez: "I learned that if you are passionate about a cause and are willing to work hard, there is a place for you in D.C."
Shangir Siddique: "The friends and connections I made as an Archer Fellow are extremely valuable to me."
Andrene Castro: "I was able to leverage my role as an Archer Fellow to intern at the White House Initiative on Education Excellence for African Americans as well as produce and engage with research to inform policies."
Bailey Weiner: "[As an Archer Fellow] I valued the opportunity to live, work, and experience the epicenter of American politics and history with wonderful people from all different walks of life and various interests in public policy."
Laura Gorecki: "My experience as an Archer Fellow gave me a clearer understanding of how policies impact lives, and of how politics shapes policy."
Christopher Peña: "My internship experience gave me a unique skill set I couldn't really develop in the clinical laboratory."
Callie Jones: "My experience as an Archer Fellow has paved the way for future career success."
Ashlee R. Peña: "The most important thing I learned as an Archer Fellow is that it is never too late and you are never too old to shift the trajectory of your career."
Blanca Davila: "The Archer Fellowship experience elevated my professional path and goals to new heights!"
Scott Vitter: "The Graduate Program in Public Policy has many merits, but the element I most enjoyed was interacting with my peers from the program during class, field trips and meetings with government professionals."
David Wogan: "I value the opportunity I was given to work in a real policy setting where I actively applied my skills to issues I deeply cared about. It was one thing to talk about issues in a classroom, but another to practice making policy."
Sylvia Loh: "Prior to my Archer Fellowship experience, I believed that researchers were only sought to work in research facilities. My experience as an Archer Fellow has changed my perspective on the possibilities that can be found in 'hard' sciences."
Melody Timinsky: "Because of my experience as an Archer Fellow, I have a deeper understanding of how to secure and coordinate resources, as well as strategies for influencing policies."
Ashley Thibodeau: "My time in D.C. really familiarized me with the priorities and issues practitioners in higher education face regularly in policy and law arenas."
W. Brady Franks: "The Graduate Program in Public Policy perfectly blended an academic introduction to federal policy making and real-world experience."
Margaret Cook: "My experience as an Archer Fellow made me a more versatile engineer."
Raymond Banks: "This opportunity gave me first-hand insight into the world of politicians and public administrators."
Benedicta Anikputa: "I value the opportunities I had to participate in events that aligned with my interest."
Andrés Gallardo: "Having the opportunity to meet people with such different motivations, goals, and backgrounds enriches the fellowship."
Addison Larson: "The conversations I began in D.C. continue to this day."
Alafifi: "Being an Archer Fellow solidified my goal to be involved in policy making as a physician."
Jolie Schafer: "As a fellow you will have doors open to you that other D.C. interns will not."
Emily Diaz-Melendez: "I value the friendships I formed while in the program."
Joaquin Villegas: "The Archer Center Fellowship helped me realize that there is a place for all of us to help dictate policy changes."
Wei-Ling Sun: "The Archer Program opened opportunities and demystified federal public policy."


"Negligent and unqualified" executives have killed online privacy. Get used to it.
Ongoing revelations of mass data breaches have become so large and so pervasive that online users simply cannot expect their data to remain private anymore, experts have warned as more and more breaches expose consumers' personal details by the hundreds of millions.
Shifting the burden to consumers is likely to prove easier said than done, however. Also responding to the Yahoo revelations, Mimecast director of security product management Steve Malone noted that many users "will have reused their Yahoo email password in the workplace" – creating an easy pathway for hackers to gain access to internal work emails that can help them launch internal phishing attacks and escalate their privileges on the network.
Figures suggest that most consumers would neither know nor care if this happened. A recent Ponemon Institute-Centrify study found that just 15 percent of consumers nominated 'performing work-related activities' as one of the times when their privacy and security were most important to them.
This was far behind 'using social media' – when 62 percent of respondents said privacy and security were important – and 'visiting a healthcare provider', cited as important by 75 percent of respondents. Also surprisingly, just 34 percent of respondents said privacy and security were important when making a credit card purchase online.
That research showed a strong mismatch between consumers' security priorities and their perceptions of various industries in protecting their data: for instance, just 17 percent of respondents said they trusted social-media companies to preserve their privacy and protect their personal information and just 27 percent trusted credit-card companies to do the same.
Cybersecurity think tank the Institute for Critical Infrastructure Technology recently issued a scathing assessment of the implications of the recent mass data breaches, with senior fellow James Scott warning that "the reckless handling of data collected in capitalistic dragnet surveillance has developed into a national security and privacy epidemic".
Yahoo executives were similarly blamed for botching their response in the investigation after the original breach was made public. Yet even as the full implications of Equifax, Yahoo and other breaches continue to emerge, analysts advised that consumers take advantage of access-control protections such as two-factor authentication to protect access to their online accounts.
Anticipating abuse of the stolen data – whether by using Yahoo passwords to log onto work systems, or by watching medical and financial services for unusual or unexpected activity – has become an unavoidable obligation in the effort to contain damage from what is now being seen as the inevitable compromise of personal data.
With new data breaches emerging on a regular basis, things are likely to get worse before they get better. And for organisations to bolster their protections of personal data, Sense of Security chief operating officer Murray Goldschmidt recently told CSO Australia, they need to improve corporate security culture by building – and implementing more realistic cyber risk and data controls.


This impressive, three bedroom, lower apartment enjoys a peaceful setting and is just a short distance from Hamilton Town Centre. 'The Paddock' is widely regarded as the preferred luxury development within Hamilton, due to its location in relation to Hamilton Park and, indeed, the stunning open parkland views over Strathclyde Park Golf Course and beyond. The apartment is located on the ground floor of this four storey block and has the benefit of uninterrupted views of the well-tended garden grounds and Racecourse beyond. The apartment has been well designed to maximise the natural available light, creating a modern ambience, and has been recently re-decorated with a contemporary theme. Room dimensions are generous and the accommodation has been arranged to offer flexibility and a high level of individuality.
In more detail, the property comprises; a welcoming entrance hall with a handy storage cupboard. The bright and airy dual aspect lounge/diner is a perfect area for relaxing or entertaining and benefits from a walk-in bay window to the rear aspect. There is ample space for a dining table and chairs in this zone for more formal gatherings with friends and family. The kitchen/breakfast room has been beautifully fitted to include a good range of contemporary floor and wall mounted units, with a striking worktop, which provides a fashionable and efficient workspace. It further benefits from an integrated oven, hob, extractor hood, fridge freezer, dishwasher and a washer/dryer, making this the ideal kitchen for an aspiring chef. There is also room for a small dining table for more informal gatherings.
Clear, crisp and contemporary styling continues into the three spacious bedrooms, with bespoke storage facilities. The cleverly designed en-suite shower room features a walk-in shower. The sleek main bathroom exudes luxury, with an elegant white suite that includes stylish tiling, demonstrating 'McLean Builders' attention to detail.
Externally, there is a private parking space and ample visitor parking.


I truly love her videos. She has a lovely, relaxed and poised way of delevering her information. I feel as though I am in the room with her and she's teaching just me!
Take a moment to listen, and enjoy.
I have long been fascinated by cloth, clothing, the making of it, the design of it, the architecture of it, the grace of it, and the evolution of it. Throughout my life I have involved myself in many aspects of all of the above. My fascination continues, and my experience, years and years, and my desire to surround myself with "it" in every way, brought me to create this blog, to share all & everything about it that touches me in some way.
Weekly posts showing the process of a particular project which inspires me, and often daily posts about my ongoing experience of life and fashion in Paris.


The five books of Torah are the blueprint for creation. Each Torah portion presents one dimension of the vast eternal plan. The Lubavitcher Rebbe in his talks revealed the theme of each portion. Presented here is a class on one of these talks.


The Minnesota Timberwolves lost at home on Saturday night to the Philadelphia 76ers.
Minnesota got off to a rough start.
They put up only 20 points to Philadelphia's 38 in the opening quarter. They started to find something in the second, but still trailed 68-55 at the half.
In the second half the Timberwolves outscored the 76ers 54-50, but that was just not enough for them to get caught up. Minnesota fell to Philadelphia 118-109.
Andrew Wiggins led the team with 24 points. Karl-Anthony Towns tallied 21, and Gorgui Dieng added 13.
The Wolves fall to 34-42. They will play the first of their final six games on Monday night against Portland. Pre-game starts at 6:30 p.m. on AM 1240 WJON.


Police have charged a pair of former Kimbolton School teachers with a number of sexual offences against children.
Simon Ball, 42, of Coombe Avenue, Greenwich, London, was arrested on February 10, 2015, in connection with allegations of sexual relations with young girls.
Seven of the charges relate to one girl while Ball was teaching at Kimbolton, the remaining charges relate to three girls during a period when Ball was teaching at a previous school in Yorkshire.
Both have been bailed to appear at Cambridge Magistrates' Court on April 5.


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Dorman Funeral Home
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We would like to offer our sincere support to anyone coping with grief. Enter your email below for our complimentary daily grief messages. Messages run for up to one year and you can stop at any time. Your email will not be used for any other purpose.
Steven Clark Pence
October 28, 1958 ~ January 11, 2023 (age 64) 64 Years Old
Obituary & Services
Read more about the life story of Steven and share your memory.
Steven Clark Pence, 64, of Mauriceville, Texas, passed away on January 11, 2023, in Beaumont, Texas.
Steve, as he was known to all, was born on October 28, 1958, to Marjorie Robison Dearmond and Herbert Don Pence. Over the years he worked as a tugboat pilot, welder, pipefitter, and plumber. He was an active member of the Fraternal Order of Eagles in Nederland, Texas. Steve was a lifelong music enthusiast and 1970's rock aficionado. He was an avid guitar player and enjoyed "jam sessions" with his brothers, Mike and David. He was a follower of Jesus and enjoyed reading the bible given to him by his brother, Mike. He loved his daughters, grandkids, and nieces and nephews and was affectionately known by his grandchildren as "Paw-Paw P."
He was preceded in death by his parents; and brother, Mike Pence. Those left to cherish his memory are his daughters, Erin Dorsett and husband, Michael, Amy Denton and husband, Brandon; brother, David Pence; sisters, Dana McCaskill and husband, James, Donna Turner and husband, Craig, Cindy LeJune, Wendy Elliot and husband, Kenny; grandchildren, Lily Dorsett, Caroline Dorsett, Ruby Dorsett, Emma Dorsett, Cassidy Denton, Luke Denton; and numerous nephews, and nieces.
A memorial service will be held at Cornerstone Church of Liberty, TX, 1693 Hwy 146 Bypass, Liberty, TX 77575, at 2pm, on Sunday, January 22, 2023. Officiating the service will be Pastor Michael Dorsett. Arrangements were made under the care of Dorman Funeral Home.
To send flowers to the family or plant a tree in memory of Steven Clark Pence, please visit our floral store.
Cornerstone Church-Liberty
Liberty, TX 77575
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Steven Pence
October 28, 1958-January 11, 2023
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Reprinted with permission from Fried Chicken (Ten Speed Press, 2015).
Process garlic and ginger in a food processor fitted with the metal blade until finely chopped. Add salt, chili sauce, soy sauce, sesame oil, egg, cornstarch, flour, and pepper and pulse twice to combine. Transfer marinade to a large mixing bowl.
To form lollipops, grab exposed bone at end of each drumette and use a paring knife to push all meat to the other end, exposing the bone and forming a rounded lump of meat at 1 end (to look like a lollipop). The bone should be stripped of all meat to form about a 1-inch stick for the lollipop. Transfer chicken to bowl with marinade, toss to coat, cover, and refrigerate for 1 hour.
In a deep fryer or large, deep stockpot, heat 2 inches peanut oil over high heat to 350 degrees. Set a wire rack over a rimmed baking sheet.
Remove chicken from marinade and discard marinade. Carefully place lollipops in hot oil and fry 6 to 8 minutes, or until golden brown. Maintain a frying temperature of 325 degrees. Drain lollipops on wire rack. Serve sprinkled with cilantro.
*Drumettes are the parts of wings that look like tiny drumsticks. They are perfect for appetizers or tailgating before a big game. Using a paring knife to transform them into the shape of lollipops takes a little time, but it's worth the oohs and aahs from hungry fans.


And thank goodness it is Friday! Life for me is a little busy to say the least at the moment. However, the light at the end of the tunnel is slowly moving closer.
My first share today is of the November #3 sketch from the gorgeous Sketches in Thyme Blog. All of the Mavens have a go at this sketch.....make sure you head on over there and check out the gorgeous work from the Mavens.
I just love this sketch. It is nice to do a double layout.., I don't get to do them as often anymore!!
I have used some of the first photos Jason and I had with Brayden in 2005.
I apologise for the photos......they are not the best.
I have used 'Echo Park - A Boy's Life' paper collection. It is such gorgeous boy paper.
Here is a close up of the other side and the journalling.
Now why don't you head on over to Sketches in Thyme by clicking this link - check out the Mavens interpretations and then enter your own!
While we are talking about entering your interpretations. I hope you have been over to Scrapbookit. You have until the 14th of December to get your entries in for your chance to win!
Better head back to writing school reports.
Well I can't begin to describe to you how excited I am today to be able to share with you my very first project as a Maven on the Sketches in Thyme Design Team.
Each week Sketches in Thyme have a sketch challenge.
I had lots of fun completing my layout. I just loved this sketch.
I also had another play with some photos of our overseas holiday to Thailand in 2009.
I actually pulled out some of an older range from Kaisercraft to use. I get so hooked with all of the gorgeous new paper collections that I often forget to hit my stash...... it is nice to go back and use something from your stash!
Paper - Kaisercraft 'Marrakech'; Bazzil Cardstock; Thickers - Chit Chat Puffy Stickers ; twine; Versamark Ink - Royal Blue; Kaisercraft Mini Alphas - Cream; Stampin' Write - Chocolate; Making Memories Paint - Monarch; Kaisercraft - Chicken Wire Clear Stamp.
We would really love for you to play along and enter your own interpretation of the sketch!
Make sure you pop back soon for my latest Scrapbookit project!
A few exciting announcements !!!!!
A HUGE Congratulations to Jo from Scrapbookit.
Yesterday (1/11/12) the brand new and improved shop was opened in Porepunkah allowing more space, a bigger class space and lots of great new products. How exciting!
I look forward to hopefully checking out the new shop over the weekend. Can't wait!!
Today I have some other very exciting news to share. I have known for a few days but have had to keep it a little quiet. Luckily I have been really busy so time has gone quickly.
Recently I applied to become a Design Team Maven over at Sketches in Thyme.
And yes you guessed it.....I am now one of the new Design Team Mavens.
Sketches in Thyme is a blog that provides weekly sketches to spark your creativity.
There are lots of very clever Mavens on the team who inspire scrapbookers with gorgeous layouts all month.
I am really looking forward to being part of the Sketches in Thyme Design Team and hope that you are able to pop over to the blog at some point and check it out.
Head over to check out the blog now by clicking here.
Hope all of our American friends are OK after the awful situation of Hurricane Sandy.


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Сойнчула () — невключённая территория в Канаде. Расположена на острове  в Тихом океане на западе канадской провинции Британская Колумбия. Поселение основано в 1901 году, согласно переписи населения 2021 года насчитывает более 500 жителей.

География
Сойнчула расположена на острове Малколм в проливе Королевы Шарлотты между островом Ванкувер и континентальной частью Британской Колумбии. Малколм находится недалеко от северо-восточной оконечности острова Ванкувер, и Сойнчула является его основным портом и наиболее важным населённым пунктом.

Площадь Сойнчулы — 5,2 км². Регулярная связь с внешним миром поддерживается с помощью паромной линии, соединяющей Сойнчулу с Порт-Макниллом на острове Ванкувер; продолжительность рейса составляет 25 минут. В 5 км от Сойнчулы, на северном побережье острова Малколм, расположен региональный парк Бир-Пойнт — популярное место отдыха для местных жителей и туристическая достопримечательность.

История
К началу XX века в Британской Колумбии насчитывалось значительное количество иммигрантов из Финляндии, в это время бывшей частью Российской империи. Среди них выделялась политически активная группа рабочих с угольных копей Джеймса Дансмьюира близ Нанаймо на острове Ванкувер. В 1900 году эта группа, вдохновлённая публикациями ещё одного финского иммигранта, Матти Курикки, пригласила его в Канаду из Австралии, куда он изначально перебрался из России и где пытался организовать финскую колонию в Квинсленде. Идеология Курикки представляла собой смесь влияний марксистского социализма, толстовства, теософии и собственной трактовки христианства, кроме того, одним из основных её положений было полное равноправие женщин. Однако сам он был слабым организатором и по прибытии в Канаду привлёк к своей деятельности друга из Финляндии — Августа Бернгарда Мяккелю, бывшего одновременно бо́льшим прагматиком и более ортодоксальным марксистом.

Деятельность Курикки и Мяккели (в Канаде взявшего имя Остин Маккела) в Британской Колумбии началась с издания первой в Канаде газеты на финском языке Aika, но вскоре идея основания собственной колонии, основанной на идеалах Курикки, снова оказалась в центре его внимания. Поселенческое общество, носившее название «Калеван Канса» («Народ Калева»), сумело в ноябре 1901 года договориться с верховным комиссаром коронных земель Британской Колумбии о 7-летней аренде 28 тысяч акров (примерно 113 км²) территории на незаселённом острове Малколм. Поселенцы могли получить эту землю в собственность, а территория поселения могла быть расширена, если будут достигнуты заранее оговоренные успехи в области благоустройства острова. На основании юридических тонкостей располагавшиеся на территории колонии леса перешли в её владение немедленно.

Заселение острова Малколм (на финский лад переименованного в Малкосаари) началось весной 1902 года. В июне новое поселение получило название Сойнчула. Его население быстро росло, к концу года превысив 200 человек, но большинство из них не обладали наиболее нужными для планов Курикки профессиями — земледельцев и лесорубов. Среди поселенцев преобладали различные ремесленники (включая портных и кузнецов), имелся также собственный врач. Мужчин при этом было почти вдвое больше, чем женщин. Закон общины гарантировал всем её постоянным членам право на труд, пособия по болезни и пенсию. Большинство детей Сойнчулы росли в общинных центрах, откуда их забирали домой только на ночь. Особое место в истории колонии занимает вопрос женского равноправия: уже в 1902 году женщины Сойнчулы получили право голоса на выборах, а их труд с самого начала существования колонии оплачивался наравне с мужским (1 доллар в день независимо от характера выполняемой работы).

Хотя предполагалось, что земли острова плодородны, они густо заросли лесом, сильно отличавшимся от привычных для финнов пород. Большие деревья Британской Колумбии, древесина которых содержала значительное количество влаги, плохо поддавались обычному для финского земледелия способу очистки почвы, заключавшемуся в выжигании леса. Участки леса приходилось выжигать по несколько раз, что приводило к разрушению верхнего плодородного слоя почвы. Таким образом, жители Сойнчулы вскоре практически отказались от планов полеводства. Страдало и животноводство — для скота не удавалось запасти достаточно кормов, и их приходилось везти с острова Ванкувер. Вместо этого колонисты сосредоточились на охоте и рыбалке. Сам Курикка был сторонником вегетарианства, но эта идея понимания у поселенцев не нашла. В январе 1903 года тяжесть положения колонистов усугубил пожар, уничтоживший главное жилое здание посёлка и унесший жизни 11 человек.

Единственным продуктом экспорта Сойнчулы на первых порах оставалась сырая древесина. Небольшое количество пиломатериалов, производимых в колонии, шло на собственные нужды. Летом 1904 года было закончено строительство современной лесопилки, начата выработка электроэнергии, а недалеко от Сойнчулы были обнаружены залежи высококачественного известняка. Пытаясь укрепить статус колонии, Курикка добился получения контракта на строительство двух мостов близ Ванкувера из собственных материалов и с привлечением собственной рабочей силы. Проект, однако, оказался глубоко убыточным и только подорвал экономику колонии. Осенью 1904 года Курикка с наиболее верными своими последователями покинул Сойнчулу, которую затем несколько десятилетий возглавлял Мякеля (одновременно выполнявший обязанности мирового судьи и смотрителя маяка Палтни-Пойнт, расположенного на острове Малколм). Выпуск газеты Aika прекратился уже в июле того же года, а в 1905 году поселенческое общество «Калеван Канса» было официально ликвидировано.

Чтобы расплатиться с долгами, колонистам пришлось продать принадлежавший Сойнчуле лес, а в 1907 году — и лесопилку. Основным занятием для её мужчин стала работа в рыболовецких артелях и на частных консервных фабриках, а зимой, в перерыве между рыболовецкими сезонами — лесозаготовки. Жители Сойнчулы играли важную роль в промысле лососёвых и палтуса в проливе Королевы Шарлотты, став авторами ряда усовершенствований в оборудовании рыболовецких судов, и к 1980-м годам среди рыбаков Сойнчулы появились первые миллионеры. Вырубка леса на острове Малколм продолжалась до 1990-х годов, и к этому времени на острове практически не осталось девственных лесов. Начиная с 1990-х годов в рыболовной индустрии Британской Колумбии начался спад, связанный с истощением ресурсов и усилением государственного регулирования этой отрасли. В итоге большую роль в экономике Сойнчулы стал играть туризм, а остров Малколм превратился в популярное место отдыха для обеспеченных жителей соседнего острова Ванкувер.

Определённое влияние социалистических идей основателей колонии продолжало ощущаться в её жизни, и Сойнчула сохраняла репутацию оплота социалистов до 1940-х годов. Так, в 1909 году именно там открылся первый кооперативный магазин в Западной Канаде — Sointula Co-op, выполнявший также функции банка и компании по торговле недвижимостью. В 1929 году там же был основан первый рыболовецкий кооператив в Британской Колумбии, но он просуществовал недолго. Многие поселенцы в 1907 году вступили в Социалистическую партию Канады, но в 1911 году из-за разногласий с её британским руководством вышли из неё и основали отделение Финской социалистической организации Канады (позже Финская организация Канады), поддерживавшей тесные отношения с компартией Канады. В 1936 году жители Сойнчулы играли ключевую роль в массовой забастовке работников консервных заводов. В межвоенный период часть поселенцев эмигрировала в советскую Карелию.

Финские поселенцы поначалу относились с предубеждением к индейцам народа кваквакэвакв, в летний сезон перебиравшимся на остров Малколм. Однако в дальнейшем отношения с этими (по определению Мякели) «естественными социалистами» стали более близкими, вплоть до появления смешанных браков между финскими иммигрантами и представителями коренного населения. Уже к 1930-м годам население Сойнчулы превысило 400 человек, но вплоть до 1950-х годов её населяли почти исключительно финские иммигранты и их потомки. Начиная с этого десятилетия на остров начали прибывать иммигранты из США — хиппи, позже уклонисты от призыва на Вьетнамскую войну. Многие из новых жителей Сойнчулы разделяли идеи утопического социализма и дали новый толчок кооперативной экономике.

Население
Согласно переписи населения 2021 года, в Сойнчуле проживали 513 человек — падение на 0,8 % по сравнению с переписью 2016 года. Средний возраст жителей — 55,7 года, медианный возраст — 61,6 года. Дети и подростки в возрасте до 14 лет включительно составляли 6 % населения, люди пенсионного возраста (65 лет и старше) — 40 %. Около 85 % населения были уроженцами Канады, более 10 % относили себя к одному или нескольким из её коренных народов; большинство иммигрантов прибыли в страну из США и Великобритании и сделали это до 1980 года. Почти для 90 % жителей родным языком был английский, имелись также финская, немецкая и японская языковые диаспоры.

60 % жителей в возрасте старше 15 лет состояли в зарегистрированном браке или проживали совместно без официальной регистрации, 20 % были разведены или вдовы. Средний размер переписной семьи составлял 2,3 человека, средний размер домохозяйства — 1,8 человека. В большинстве семей не было детей, проживающих с родителями, в семьях с детьми в среднем насчитывалось 1,5 ребёнка. В 13 % семей был только один родитель. Почти 40 % домохозяйств состояли только из одного человека.

Примечания

Литература

Ссылки
 Информационный сайт города

Невключённые территории Британской Колумбии
Финская диаспора
Социальные эксперименты

redpajama_set_name: RedPajamaWikipedia


The key to planning your evaluation is to focus on one aspect of your organization that you want to measure, whether you focus on service delivery activities or the long-term impact you have in the lives of your clients. A narrow focus on your subject matter will make the process manageable. These guides, handbooks, and models will help you map out ideas, and narrow your focus. As you review the measures evaluated by others, you may see a topic that resonates with your own interests. These resources can help you determine your focus and timeline; you will also gather basic terminology useful to conduct your evaluation and present your results.
The American Evaluation Association(AEA) provides extensive resources for planning and conducting Program Evaluation. The AEA website includes a comprehensive list of tools and resourcesfor Program Evaluation.
If you join the American Evaluation Association, you can post questions to their forum and get feedback from other members. (There is an annual fee for membership.) The American Evaluation Association also provides links to several Discussion Lists and Listservs that do not require membership.
An online course (estimated time 40 minutes) on Logic Models from the Center for Disease Control. Covers basic methods which can be applied to strategic planning or program evaluation.
Joan Othieno reviews the basics theories of identifying outcomes for a client or a group. She distinguishes outputs (activities and products) and outcomes (changes in lives of clients). She provides examples of short-term outcomes, such as changes in a client's knowledge of the effects of trauma, or understanding the value of social interaction. Centers planning short-term projects may benefit by reviewing this webinar.
Extensive resources on Logic Models from the University of Wisconsin, Extension-Program Development & Evaluation; includes a PowerPoint slide overview on logic models, and examples and templates for creating your own models.
The Center for Outcome Analysis: a non-profit which provides resources to human services and health care organizations, specifically to provide support for outcomes analysis. Provides sample surveys and scales.
A list of tips to consider when planning Program Evaluation. This list is provided by the Easy Outcomes site, a non-profit which supports program evaluation. Their site includes a free Program Evaluation workbook (2008, 118 pages) with ten steps to conduct program evaluation. (Note: this site's use of the term "outcomes" applies to general program evaluation, not the process of measuring of change over time).
W.K. Kellogg Foundation Evaluation Handbook (1998, 120 pages). This handbook (free download) provides detailed steps you can use to plan and conduct an Evaluation of your organization. The W.K. Kellogg Foundationalso includes extensive resources for grant-writing.


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Cycling On A Vegan Diet
One of the benefits of regular cycling and an active lifestyle leaves you with an appetite that can allow you to eat at will. However, in recent years more and more athletes are choosing a vegan lifestyle. Having a vegan diet means selecting from a food chain with no animals on it. This includes dairy products such as milk and cheese with only substitutes consumed such as almond milk.
It's one of the fastest growing lifestyle movements on the planet and is championed by celebrities, athletes and plant-loving chefs but can cyclists really benefit from a vegan diet? We take you through the vegan cyclist diet and if it can boost your cycling performance.
Why Veganism?
Last year was undoubtedly the year of the vegan, with more and more of us questioning whether we needed to eat meat and animal products for a meal. According to the Vegan Society, in the UK around 1% of the population now calls themselves 'vegan' and the figure is rising rapidly - driven by an increasing awareness of the alleged health benefits of a plant-based diet, and a better understanding of the environmental and animal welfare issues that can accompany processed food and a plate of steak and chips. But can cyclists lead a plant life without sacrificing performance?
"The optimal diet for a cyclist is one that doesn't leave any stone unturned. The key is to consume enough calories to maintain your training load," says Annie Simpson, performance nutritionist at OTE Sports. She adds, "A cyclist's diet is usually high in carbohydrates and is supported by protein consumed little and often. A diet rich in vitamins and minerals is vital for immune support and being conscious of hydration is also key".
Eating Enough to Train
There are enough high-profile athletes following a vegetarian or vegan diet - former world road race champion and Wattbike ambassador Lizzie Deignan, Irish national champion Matt Brammeier and ultra-endurance athlete Rich Roll - to know that it is possible to ride on alternative, meat-free food. But you need more than avo' on toast (Instagrammed, of course) to get all the nutrients you need to build and maintain an athletic body.
Because vegetarian and vegan diets rely so heavily on plants, nuts and seeds they tend to be very high in fibre. And whilst fibre is a good thing – it can help prevent heart disease and improve digestive health – the downside is that whilst eating a tonne of veggies might fill you up, it doesn't give you many calories.
For cyclists doing long rides or heavy training sessions eating enough is key to ensure you're not under-fuelled. Including calorie-dense foods like pasta, rice, sweet and white potatoes is a must, especially if you are doing long rides.
A poorly planned vegan diet can also be lacking, or low, in many critical nutrients, particularly iron, zinc, calcium, vitamin D, vitamin B12, and omega-3 fatty acids (readily available in animal products). It's vital that you keep a food and exercise diary to ensure you are not under-eating and have enough fuel to perform.
After training or riding hard your body needs to recover and your muscles need to repair. To do this it needs protein and its building blocks, amino acids. Our bodies can only produce Non-Essential Amino Acids (NEAAs). The other amino acids, known as Essential Amino Acids (EAAs), have to come from your diet or supplements, and for vegans a protein source can be hard to find. In addition, a subset of EAAs called branched-chain amino acids (especially one called Leucine), are vital for the formation and repair of muscle but these are even harder to get if you omit animal products from your diet.
Grains, nuts and seeds are a good source of EAAs but they don't all contain branched-chain amino acids. However lentils, chickpeas, peanuts, soy-based products like tofu, and soya alternatives to milk and yoghurt do. (Be aware though, that soy poses its own ethical and environmental dilemmas.)
"Protein consumption that is the hardest part [of a vegan diet]," explains Simpson. "The quantity of plant-based foods that you have to consume to meet the necessary protein requirements for an athlete can be quite over facing, but more and more vegan friendly protein powders - such as the OTE Soya Recovery Drink - are becoming readily available to help with this".
Boosting Your Cycling Performance
But are there actual performance benefits to be had from ditching meat, eggs and dairy? In truth it's hard to know. Anecdotal evidence from green, lean machines like tennis stars the Williams sisters, and ultramarathoner Scott Jurek is conclusive. But in truth what scientific data there is, is lacking and far from concrete.
Simpson says, "Plant based proteins can be kinder on the stomach and are a great option for people that have GI discomfort with dairy, or are lactose intolerant and the high fibre content of the diet can help with digestion, cardiovascular health & cholesterol". Others point to the manufacturing process which can be less intensive, although this is certainly not always the case - one leading supermarket sells a 'cheddar-style coconut based alternative to cheese' which has 28 ingredients!
Achieve Success Even With a Vegan Diet
In conclusion, vegan cycling is no barrier to success but like all diets it's about balance and making the right choices - fuel your riding with chips - even sweet potato chips cooked with lashings of olive oil - and you'll never make the podium.
Annie Simpson is a performance nutritionist at OTE Sports. For more information on OTE Sports and their range of sports nutrition and healthy snacks visitOTE Sports.
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Knee Pain & Cycling
Ask the experts: How cycling can benefit your mental health
This International Coffee Day we ask: Does coffee really improve cycling performance?
Olympic Legend Aims to Improve Health of Japan's Population with the Wattbike Health Assessment
Mandy Marquardt & Team Novo Nordisk - providing a platform for elite athletes with type 1 diabetes
How to sleep your way to better cycling performance
Dealing with DOMS
Turbo Trainer Comparison
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Abitare "Berlin
Flexible urban backgrounds
Through eight international projects Nicola Russi discusses the topic of the transformation of urban voids in an essay
The Eger brothers' home
On the main floor of a 19th-century building in Berlin, David Kohn Architects have installed the new offices of the real-estate developer Euroboden, taking inspiration from Sir John Soane to create an air of "productive domesticity"
Tales of the future
From Seoul to Dubai, from Berlin to Rio de Janeiro, more and more new and spectacular museums are being devoted to the most advanced technologies, helping us to imagine what tomorrow has in store for us. In part thanks to artificial intelligence and augmented reality
Corbusian polychromy
A single apartment in the Unité d'Habitation in Berlin has been restored to its original appearance by Philipp Mohr through an accurate and faithful piece of work that has re-established its proportions and furnishings. The result is particularly surprising in terms of its pictorial...
Syria, reconstructing heritage
Al Pergamon Museum di Berlino sono in mostra per la prima volta i documenti del "Syrian Heritage Archive Project", fondamentali per la ricostruzione del patrimonio artistico della Siria
Street art goes to the museum
Berlin inaugurates a museum dedicated to the world's street artists. Studio Graft conceived a façade that is a work in progress
17 days devoted to the future of the city
From 14 June Berlin hosts the second edition of the MakeCity festival for architecture and urban alternatives
Architects meet in Berlin
More than 2,000 designers – many big names but also some less well-known studios – will be at the tenth World Architecture Festival. From 15 to 17 November
80 playgrounds in Berlin
A guide to some of Berlin's many children's playgrounds. Each one a world unto itself, designed to encourage learning
Calvenzi remembers Basilico
To mark three new exhibitions dedicated to Gabriele Basilico, Abitare revisits the travels, the passions and the professional journey of the great photographer with Giovanna Calvenzi, a photo editor and his life partner
Society and the urban environment
The repercussions of politics and economics on the shape of the city are at the centre of an exhibition in Berlin that examines them through the work of 15 artists
Essential Rigour
Andrea Tognon has designed Jil Sander's boutique on the Kurfürstendamm in Berlin. This is a "tailor-made" setting that blends spatial clarity with precious details
Virtuous Re-use is Informal and Communal
From the creation of the Los Indignados protest movement in Madrid to city allotments of Berlin, from start-ups in Rotterdam to garden collectives in Bratislava. A book describes the tools and the secrets behind urban regeneration
Architects in Berlin
The winners of the International Architectural Awards of the World Architecture Festival 2016


– one of the the problems facing eighteenth-century tea drinkers both in London and in Boston was the adulteration of tea leaves a dishonest traders on both sides of the Atlantic found ways to stretching supplies by adding such things as tree leaves to their teas.
– the problem was so widespread which made it illegal to add sloe leaves, licorice leaves or the leaves of any other plant, tree or shrub that would adulterate the tea leaf.
– I shall here communicate to the public a particular account of this manufacture which I have lately received from a gentleman who made very accurate inquiries is on the subject of making smooch with ashe leaves.
– When gathered, leaves are first dried in the sun then baked, they're next put on the floor trod upon until the leaves are small then lifted and steamed with sheep dung after which being dried on the floor they are fit for use.
– Hyson green tea, an early spring tea from China, which was a favorite of about Thomas jefferson and george washington. the sign above hyson's door proudly proclaims his teas free from any deception.
– and one of his tea chests being carried to an awaiting carriage bears the words fine Hysen free from the adulteration of sloe leaves. I find it interesting that one of the characters in this tableau is quoted as saying my wife may drink tea now as cheap as the drink gin.
– this may have marked the beginning of the British preference for black tea which was for decades emulated by their American cousins in boston.
free from any adulterations of course. until we see you in Boston go forth and make good tea.
Author of numerous books including the Benjamin Press publications: The New Tea Companion and A Social History of Tea.


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Tax News & Views Retirement, Arizona, and Ponies Roundup
April 26, 2022 | Blog
Finance Panel 'Sifting Thru' SECURE 2.0; Wyden Expects Markup - Doug Sword, Tax Notes ($).
The House passed its retirement package March 29 on a 414-5 vote. The Securing a Strong Retirement Act of 2022 (H.R. 2954) — sometimes referred to as Retirement 2.0 or SECURE 2.0 — has roughly four dozen provisions, including many that are also in the Retirement Security and Savings Act of 2021 (S. 1770). That Senate bill has been developed in the Finance Committee over the last three Congresses by Finance Committee members Benjamin L. Cardin, D-Md., and Rob Portman, R-Ohio.
There appears to be wide agreement on many of the provisions, including one to allow an employee's payment on a student loan to count toward an employer match on a 401(k), 403(b), 457(b), or SIMPLE IRA plan. Another provision with wide bipartisan support would boost the required minimum distribution age from 72 to 75.
Related: Retirement legislation that sailed through tax-writing committee faces rockier path on passing Congress.
Ariz. Justices Toss Referendum Challenging Flat Tax Law - Paul Williams, Law360 Tax Authority ($):
In a short order released Thursday, Chief Justice Robert Brutinel said Proposition 307 couldn't be placed on the Nov. 8 ballot because the law it targeted, S.B. 1828, qualified for a "support and maintenance" exception in the Arizona Constitution that protects certain laws from being referred to the voters. The Maricopa County Superior Court had found that the law didn't fall within the exception's criteria because it didn't "appropriate state funds or generate necessary revenue," according to the state high court's order. The justices will release a full opinion at a later date.
Republican Gov. Doug Ducey signed S.B. 1828 last June, which reduced Arizona's four income tax brackets that ranged from 2.59% to 4.5% to a two-bracket system in 2022 with rates of 2.55% and 2.98%. Revenue triggers will determine if the rates should remain the same, be cut to 2.53% and 2.75% or if Arizona would move to a flat tax of 2.5%.
Consumer Brands Push for Clean-Energy Tax Credits- Katy Stech Ferek and Timothy Puko, Wall Street Journal ($). "They called for federal tax credits for developers and suppliers of major wind, solar, nuclear and energy-storage projects, as well as for electric vehicles and charging-station tax credits, which could benefit company-run fleets."
Pot taxes surpass those from alcohol in legalization states - Reid Wilson, The Hill. "The report, from the Institute on Taxation and Economic Policy, found the 11 states where marijuana is legal pulled in just shy of $3 billion in excise taxes on pot in 2021, compared with about $2.5 billion they made on alcohol excise taxes or liquor store profits."
California Men Sentenced To More Than Six Years For International Tax Fraud Scheme - US Department of Justice (defendants names omitted):
According to court documents, from Summer 2014 through approximately Spring 2018, Defendants... operated a scheme to defraud the United States government of more than $17 million through the filing of false and fraudulent tax returns in the names of hundreds of identity theft victims. The conspirators used sophisticated cyber means to obtain the personal data used to file the tax returns. Conspirators—including individuals located in Nigeria and Vietnam—then prepared and filed the returns quickly and in large batches. The tax returns were filed from real CPA firms across the United States, all of whom had been hacked.
There's a lot of disturbing stuff here. The operation continued for almost four years. Thieves seem to have had no difficulty finding CPA firms with vulnerable IT systems, and the firms apparently didn't realize that third parties were submitting ID-theft returns through them. It is a sobering reminder of the importance of information security - both for taxpayers and for firms.
Ranking Unemployment Insurance Taxes on Our 2022 State Business Tax Climate Index - Janelle Cammenga, Tax Policy Blog. "Compared to individual, corporate, sales, and property taxes, UI taxes are less widely understood, but they have important implications for a state's business climate. A state's performance on the UI tax component accounts for 9.8 percent of that state's overall Index score."
In states with Eide Bailly offices, Oklahoma has the highest ranking - in fact, number 1 overall.
5 post-filing tax tasks to take care of now - Kay Bell, Don't Mess With Taxes. "Adjusting your withholding is easy. Start by using the IRS' online Tax Withholding Estimator. It will help you make sure you're withholding the appropriate amount to avoid either owing or getting a huge refund at tax filing time. Then using the revised withholding amount, complete a new Form W-4 and give it to your payroll administrator. The results will soon show up in your future paychecks."
2022 Tax Season: The Tax Season From Hell (Part 1) - Russ Fox, Taxable Talk. "Government regulations cause the tax professional community to shrink. There's an excellent quote: 'Whatever you tax you get less of.' Regulations have the same impact. My professional society, the National Association of Enrolled Agents (NAEA), strongly believes that the IRS should regulate all tax professionals because it would weed out bad preparers. I disagree. If someone wants to be a bad professional, it's easy and no amount of regulation will stop it. It's 'whack-a-mole.' But regulations also make it harder for me to operate, with costs passed on to you (the taxpayer)."
Volunteer Tax Prep Is A Crash Course in Pandemic Tax Policy - Richard Auxier, TaxVox. "But leaving policy aside for a minute, our client's federal tax liability was the result of his failure to withhold taxes owed. We often see a similar problem with clients who get nonemployee compensation for house cleaning and construction jobs. These workers (who sometimes are mislabeled employees) don't have tax withheld from their paychecks throughout the year and can end up owing thousands of dollars (that they don't have) in income and payroll tax when they file. Unfortunately, the ins-and-outs of tax withholding are rarely discussed with them, especially if they speak English as a second language, until they're staring at a massive tax bill."
Payroll Taxes Funded the Most Scandalous Frauds in 2020 and 2021 - Carrie Brandon Elliot, Tax Notes Opinions. "For two years in a row, the Association of Certified Fraud Examiners has placed theft of pandemic-related enhanced unemployment benefits at the top of its annual list of five most scandalous frauds."
Taxpayers Fall Far Short of Qualifying as Real Estate Professionals - Ed Zollars, Current Federal Tax Developments. "Rental activities are generally treated as passive activities under IRC §469, limiting the ability of taxpayers to offset losses from such activities against other income. However, a special rule applies to individuals who can meet the qualifications to be a real estate professional under IRC §469(c)(7)."
Corporate Officer Can't Avoid Employee Classification for Employment Tax Purposes - Parker Tax Pro Library. "The Tax Court held that a corporation, which was organized by an individual as a vehicle to offer online courses on real estate development, was liable for employment taxes on the remuneration paid to that individual because, as an officer of the corporation, the individual qualified as an employee under Code Sec. 3121(d)(1). The court rejected the corporation's assertion that the individual performed services in dual capacities as both an officer-employee and an independent contractor and found that the minor services exception of Reg. Sec. 31.3121-1(b) did not apply."
You Received an IRS CP504 Notice, Now What? - Gregory Mitchell, Freeman Law. "The IRS sends a CP504 Notice when a taxpayer has failed to pay a balance owed. The CP504 Notice is a Notice of Intent to Levy issued pursuant to Section 6331(d) of the Internal Revenue Code."
2022 1st Quarter Published Expatriates - International Tax Blog. "The number of published expatriates for the quarter was 568... The 8-quarter moving average has how now dipped significantly below 1,000 names per quarter"
Prop regs fix a PTC issue 7 years later - Annette Nellen, 21st Century Taxation. "A 4/5/22 Tweet from the Treasury Dept indicates that this change should enable about 1 million people to save hundreds of dollars per month on their coverage."
Sending 1099s doesn't help Ponzi Scheme Operator. A US District Court in Indiana was asked to reconsider whether its sentincing of a convicted Ponzi scheme operator. The sentence took into account "sophisticated means" used to convince investors that they were really earning money, rather than having it stolen by the operator. One of the sophisticated means was the issuance of 1099s for (imaginary) investment earnings credited to the investors.
The defendant had an interesting argument. From the district court opinion: (defendant name omitted):
Defendant insists that producing 1099 tax forms and filing tax returns on what was imaginary interest income for some of the clients didn't reflect sophisticated means designed to cover up his crimes. He relies on 26 C.F.R. § 1.451-2(a) which explains that "[i]ncome although not actually reduced to a taxpayer's possession is constructively received by him in the taxable year during which it is credited to his account, set apart for him, or otherwise made available so that he may draw upon it at any time, or so that he could have drawn upon it during the taxable year if notice of intention to withdraw had been given." Defendant argues that he was obligated by law to report to the Internal Revenue Service his clients' purported interest earnings on their investments as income, which, according to him, proves that he was not using sophisticated means to carry out or conceal his crimes.
The court was unimpressed:
Defendant misunderstands the reasons for the Court's finding that he utilized sophisticated means. While it is true, as Defendant points out, that some of the investors chose and received monthly interest payments, many others elected to roll over their interest amounts. As to this latter group, his creation of 1099 tax forms and his filing of tax returns on the purportedly accrued interest, whether legally required or not, was a fiction — fraud, to be exact. The reported interest did not exist, that is, it was not "made available so that [the investors] may draw upon it at any time." 26 C.F.R. § 1.451-2(a). Rather, Defendant had stolen the investors' money, which resulted in the money being unavailable for withdrawal. In fact, as Ponzi schemes do, his scheme also came to a crashing end because the new money dried up and could not be withdrawn by older investors. Therefore, the creation of 1099 forms and resulting tax returns perpetuated the lie that the investments were safe... and were earning interest.
The moral? First, the obvious - beware "safe" investments paying mysteriously-high returns. And if you choose to steal investor money, issuing 1099s won't score you any points when the chickens come home to roost.
Do ponies file tax returns? Today is National Help a Horse Day, "to create awareness around taking better care of horses."


This is a very gorgeous ring that would make a great gift! This piece of jewelry is crafted out of genuine sterling silver and real Turquoise inlay. The inlay is gently set, while creating a fabulous design. Thin silver lines and stamped border patterns can be seen accenting the ring for a beautiful finish. The ring is stamped sterling and hallmarked.


After three years across the Atlantic, 23-year-old forward Evgeny Dadonov (pictured sporting Traktor colors in the first KHL season) is close to confirming his return to the KHL – but his departure from a frustrating stint at Carolina Hurricanes has sparked a bidding war for his services.
Traktor Chelyabinsk, where Dadonov learned his craft, have first refusal, but the Ural club's offer has been bettered by KHL newcomers Donbass Donetsk. Traktor has a week to match that deal, or face losing out on another player who emerged through the ranks.
In Chelyabinsk, head coach Valery Belousov has told Sovietsky Sport that he will not respond to questions about Dadonov until after his holiday. But in Ukraine, there is great enthusiasm about the player's prospects with Donbass.
Dadonov went to the US in 2009, initially signing for Florida Panthers where he played 55 games and managed 20 points in two-and-a-half years. But in January, with his contract running down, he was traded to Carolina where he was unable to break into the team, and according to agent Sergei Paremuzov he is now keen to return to the KHL in search of more game time.
While young Dadonov waits to hear if Traktor will make a renewed bid, speculation is growing about veteran Czech star Petr Nedved, linked with Avangard Omsk.
The 40-year-old, who has more than 1,000 NHL appearances under his belt, posted 74 points for Liberec in last season's Czech Ekstraliga and is keen to take his chance of another season at a higher level in the KHL.
However, the player's agent, Vladimir Vujtek Jr, has made it clear that Nedved won't appear in the colors of newly-admitted Czech team Lev Prague, seeking a role with a club that has serious title aspirations.
Avangard, last season's runner-up, would fit that bill, and the Siberian side – which once boasted another Czech legend, Jaromir Jagr, on the roster – is believed to be one of several KHL outfits to express an interest in Nedved.


Terry Speed completed a BSc (Hons) in mathematics and statistics at the University of Melbourne (1965), and a PhD in mathematics at Monash University (1969).
He held appointments at the University of Sheffield, UK (1969-73) and the University of Western Australia in Perth (1974-82), and he was with Australia's CSIRO between 1983 and 1987.
In 1987 he moved to the Department of Statistics at the University of California at Berkeley (UCB), and has remained with them ever since.
In 1997 he took an appointment with the Walter & Eliza Hall Institute of Medical Research (WEHI) in Melbourne, Australia, and was 50:50 UCB:WEHI until 2009, when he became emeritus professor at UCB and full-time at WEHI, where he heads the Bioinformatics Division.
His research interests lie in the application of statistics to genetics and genomics, and to related fields such as proteomics, metabolomics and epigenomics.


As part of its anti-corruption project requires the services of a consultant to undertake a study on the typology and nature of corruption risks in Ghana's extractive sector.
Interested persons should contact Frank Bimpong – kkbimp@yahoo.com or 0275859384 with their CVs and a statement on why they believe they are best suited for the assignment.
Application deadline: Thursday, June 28, 2018.


I found a loophole to get unlimited PR-7 actual page dofollow backlinks.
In this WSO I'll show you a method to get unlimited PR-7 actual page backlinks in just Minutes.
To skyrocket your website to the top of google instantly.


4 July 2011, at 1:00a.m.
NORWAY - Large amounts of rapeseed from the production of biodiesel can be used in feed for Nile tilapia, one of the most important fish species in global aquaculture.
"The world needs food and the world needs energy. Therefore it is so exciting to upgrade by-products from biodiesel, in this case rapeseed meal, to a better protein source for fish," said Trond Storebakken.
He is professor at the Aquaculture Protein Centre, a Norwegian Centre of Excellence that is affiliated with the Norwegian University of Life Science (UMB).
PhD student Youling Gao flankert by his supervisors. From right: Professor Trond Storebakken (APC/UMB), Professor Margareth Øverland (APC/UMB), and reserach scientist Jon Fredrik Hanssen (UMB).
The Chinese PhD student Youling Gao recently proved that high amounts of rapeseed meal can be used efficiently in feed for tilapia.
"We observed fast growth, efficient feed utilisation, and found no health problems," Mr Storebakken said.
The access to protein rich rapeseed meal will increase as the demand for rapeseed oil for biofuel increases. The disadvantage with rapeseed meal from biofuel production is that unwanted substances called glucosinolates are concentrated in the meal.
These substances are natural pesticides for the plant and protect the rapeseed against being eaten by insects.
They are not poisonous in themselves, but are transformed to toxins by an enzyme in the rapeseed when the plant is damaged or attacked by insects. The same type of enzymes can be activated when rapeseeds are processed into feed.
Once rid of these glucosinolates, rapeseed meal will be an even better protein source for farmed fish.
Recently, APC tried to destroy the glucosinolates by subjecting rapeseed meal to solid-state fermentation.
In the trials preformed by APC it was difficult to obtain stable conditions during fermentation, but the tilapia grew better on fermented rapeseed meal, than on untreated rapeseed meal.
This young Nile tilapia can grow big on fermented rapeseed meal from biodiesel production, if the scientists from the Aquaculture Protein Center succeed.
Scientists from APC, therefore, moved on to find out how to efficiently use rapeseed meal from the production of biodiesel in feed for tilapia, with the help of fermentation.
Ruminants have an effective way of getting rid of glucosinolates, by letting microbes in the rumen ferment the feed.
"Inspired by what's going on in the rumen, we're now trying out wet fermentation with two different cultures of microbes. While the first culture of microbes shall remove the fibre network that protects the glucosinolates, the next will destroy them once released," said Olav Fjeld Kraugerud, postdoctor at APC.
The conditions at the lab are naturally not identical to the rumen, but the main principles are the same.
Rapeseed is the most important protein producing plant on world basis next to soy. But the use of this plant for other animals than ruminants is limited because of glucosinolates and phytic acid. These are the substances APC are endeavouring to remove.
"With the large interest we're seeing on using the oil from rapeseeds to produce biodiesel, the protein is left over and we have to utilise it for food," said Mr Storebakken.
Nile tilapia is a very important fish for farming in the Southeast Asia and South America, but its origin is Africa.
Norwegian research institutions have been crucial to facilitate the production of tilapia, as the food research institute Nofima was a central developer of a selective breeding programme for tilapia.
"Today, tilapia from this breeding programme are extremely fast growing, and they efficiently utilise feed based on inexpensive plant ingredients. That's why we want to utilise the inexpensive rapeseed meal from biodiesel production, that is not suitable for direct human consumption, in feed for exactly this species," said Storebakken.
The tilapias that APC have used in the experiments are farmed at UMB in Norway. APC use tilapia in nutritional research, where they work on different aspects of feed and feeding of tilapia.


Celtic Knot 2018 | the Wikimedia UK blog!
The Wikipedia language conference is back, and it's coming to Wales.
In 2017 Ewan McAndrew, the Wikimedian in Residence at the University of Edinburgh launched the first Celtic Knot conference. As the name suggests the original focus of the conference was the 6 Celtic language Wikipedias including Welsh, Gaelic, Breton, Cornish and Irish. And whilst Celtic languages were well represented, the conference also attracted delegates from Norway, Catalonia and the Basque country, to name but a few.
The issues, challenges and opportunities facing smaller language communities on Wikipedia are often very different to larger Wikipedias such as English, which has a large contributor base, technical support community and 5.5 million articles. There are also advantages whereby smaller wikis can move quickly and implement new technology, as has been the case with Wikidata. Celtic Knot acts as a meeting point for these smaller communities in order to coordinate and develop ideas common to smaller wikis.
Last year there were discussions about the Sami (davvisámegiella) Wikipedia, which has just 7000 articles and a handful of editors, and the Cornish (Kernowek) Wikipedia with 3,800 articles and less than 1000 native speakers. How can we engage the speakers of these languages with their Wikipedias? And what would be the benefits and impacts of doing this successfully?
At the other end of the spectrum are the hugely successful Basque and Catalan Wikipedias with nearly 1 million articles between them. What drives their success? And what can smaller communities learn from them? The Welsh Wikipedia is being taught in schools, and is being supported by the Welsh Government – can this good practice be replicated elsewhere successfully?
Wikidata, the wiki community, bilingualism and education will all be huge themes at this years conference as we work together to grow the diversity of Wikipedia and to encourage the use of local languages in a digital environment.
The conference will be opened by the Welsh assembly Minister for Welsh Language and Lifelong Learning, Eluned Morgan, and we expect to announce more exciting speakers to the programme over the coming months.
With limited tickets available, book early to ensure your spot at the conference!


I was doing the workout before I started the business, and it gave me back a sense of control over my body," she told PEOPLE's editor-in-chief Jess Cagle, in the most recent episode of the Jess Cagle Interview.
As for how she finally stopped the cycle of bingeing and purging—or simply avoiding food altogether—she says the reality was, she was getting too old to handle it.
She adds that it wasn't easy: "Oh it was so hard," she admits.
… says 32 year-old Jameela.
I don't know if men wake up, look in the mirror and hate themselves. Most women do. So I have a big secret: I don't look in the mirror. I'm a 60-year-old woman. I am not going to look the same as I used to, and I don't want to be confronted by that every day! When I get out of the shower, I have a choice: I can dry myself off looking in the mirror, or I can dry myself off with my back to it. I turn my back to the mirror, and I feel great! I don't want women to hate themselves, because I think women are extraordinary.
Do I think I really know what works? Yeah. It's no accident that everyone says to me all the time that I still look like I did in Clueless. I see the difference if I eat a certain way for a day, so I choose to make more than one meal be that great meal. After only two weeks of being vegan, people were beginning to ask, "What is going on with you? You look amazing! I was still eating lots of white pasta, french fries, and all sorts of sludgy things (in fact, I still do sometimes). All I'd given up was meat and dairy, and yet I began to look better in just two weeks!
… says 41 Alicia in Redbook.


My friend the revolutionary artistic genius musician DJ Spooky has just come out with a DVD film of his performance Rebirth of a Nation, performed at Yale University's Art Center.
DJ Spooky reference points = William S. Burroughs' That Subliminal Kid, Grandmaster Flash, John Cage, Marcel Duchamp, Slayer, Wu Tang Clan, Iannis Xenakis, Chuck D., Meat Beat Manifesto, George Herriman's Krazy Kat, Prosthetic Realism, Thomas Edison, Black Panthers, Nietsche, W.E.B. DuBous, Ralph Waldo Emerson, the Cut Up, the Mash Up, Bill Gibson, Virtual Reality, Gilles Deleuze, Surrealism, Richard Feynman, and Andy Warhol.
You can check it all out here.
The Singularity: A Crucial Phase in Divine Self-Actualization?
Will We Eventually Upload Our Minds?


text:
Dicladispa schoutedeni es una especie de insecto coleóptero de la familia Chrysomelidae.

Fue descrita científicamente en 1923 por Gestro.

Referencias

Dicladispa


This course is a facilitator-led self learning with hands-on skills acquisition covering the essential electronic tools for writing biomedical research proposal. The primary output of the learning is a research proposal that passes ethical and scientific reviews.
The maximum duration of the training is four weeks. With dedicated time and efforts, it can be completed within a 10-14 days. Estimated hours required to complete it is 40 hours due primarily to the writing assignments, their reviews and revisions.
The fee is 50,000 Naira for 4 weeks This can be renewed at the rate of 10,000 Naira per week if necessary.


Andreia Lopes received her B. Sc and M. Sc degree in Materials Engineering from Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa in 2009. She is currently working as a researcher in a project on development of a optical microsensors based on rare-earth doped phosphate glass (SENSGLASS project). She was a researcher in a project on new glasses and glass-ceramic composite materials (2010, FCT/UNL).


text:
package sasc;

import sasc.smartcard.common.CardExplorer;
import org.apache.commons.cli.CommandLine;
import org.apache.commons.cli.CommandLineParser;
import org.apache.commons.cli.GnuParser;
import org.apache.commons.cli.HelpFormatter;
import org.apache.commons.cli.Option;
import org.apache.commons.cli.Options;
import org.apache.commons.cli.ParseException;
import sasc.terminal.Terminal;
import sasc.terminal.TerminalAPIManager;
import sasc.terminal.TerminalException;
import sasc.terminal.TerminalProvider;

/**
 *
 * @author sasc
 */
public class Main {

    /**
     * @param args the command line arguments
     */
    public static void main(String[] args) {

        //Default values
        boolean noGUI = Boolean.getBoolean("java.awt.headless");
        boolean emulate = false;
        boolean listTerminals = false;
        boolean verbose = false;

        //Commons CLI
        //http://commons.apache.org/cli/usage.html

        Option helpOption = new Option("help", "print this message");
        Option noGUIOption = new Option("noGUI", "use command line version");
        Option emulateOption = new Option("emulate", "emulate communication with an EMV card");
        Option listTerminalsOption = new Option("listTerminals", "list all available terminals");
        Option terminalOption = new Option("terminal", "the name of the terminal to use");
        Option verboseOption = new Option("verbose", "print debug messages");

        Options options = new Options();

        options.addOption(helpOption);
        options.addOption(noGUIOption);
        options.addOption(emulateOption);
        options.addOption(listTerminalsOption);
        options.addOption(terminalOption);
        options.addOption(verboseOption);

        // create the cmd line parser
        CommandLineParser parser = new GnuParser();
        try {
            // parse the command line arguments
            CommandLine line = parser.parse(options, args);

            if (line.hasOption("help")) {
                // automatically generate the help statement
                HelpFormatter formatter = new HelpFormatter();
                formatter.printHelp("BLABLA", options, true);
                System.exit(0);
            }
            if (line.hasOption("listTerminals")) {
                listTerminals = true;
            }

            if (line.hasOption("noGUI")) {
                noGUI = true;
            }
            if (line.hasOption("emulate")) {
                emulate = true;
            }
            if (line.hasOption("verbose")) {
                verbose = true;
            }
        } catch (ParseException ex) {
            // oops, something went wrong
            System.err.println("Parsing failed.  Reason: " + ex.getMessage());
            ex.printStackTrace(System.err);
            System.exit(-1);
        }

        if (listTerminals) {
            try{
                TerminalProvider terminalProvider = TerminalAPIManager.getProvider(TerminalAPIManager.SelectionPolicy.ANY_PROVIDER);
                for(Terminal terminal : terminalProvider.listTerminals()){
                    System.out.println(terminal.getTerminalInfo());
                }
                System.exit(0);

            }catch(TerminalException ex){
                ex.printStackTrace(System.err);
                System.exit(-1);
            }
        }

        if (emulate) {
            try{
                CardEmulatorMain.main(null);
                System.exit(0);
            }catch(TerminalException ex){
                ex.printStackTrace(System.err);
                System.exit(-1);
            }
        }

        if (noGUI) {
            //No Swing/GUI
            new CardExplorer().start();
        } else {
            // Create swing app using appframework
            // http://java.dzone.com/news/jsr-296-end-jframe
            // https://appframework.dev.java.net/
            org.jdesktop.application.Application.launch(GUI.class, args);
        }
    }
}