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Home>Latest Travel News>SUNx Malta Launches "Bend Our Trend" Campaign on World Environment Day
SUNx Malta Launches "Bend Our Trend" Campaign on World Environment Day
Valetta, Malta, June 5, 2020 / TRAVELINDEX / SUNx Malta, in collaboration with the World Travel & Tourism Council (WTTC) today launched a Climate Resilience campaign called "BEND OUR TREND".
Led by a 90-second animated video, the campaign is designed to encourage Travel & Tourism companies and communities to:
Adopt Climate Friendly Travel – Low carbon, linked to the UN Sustainable Development Goals and consistent with the Paris 1.5 trajectory.
Create Climate Neutral Ambition Plans and file these on the SUNx Malta UNFCCC-linked
With the support of Malta's Minister for Tourism and Consumer Protection, Hon. Julia Farrugia Portelli, who has declared her country to be a global centre of Climate Friendly Travel, we are deploying tools to help the entire Travel & Tourism sector in its essential transformation to a 2050 Paris 1.5 trajectory.
Minister Farrugia Portelli said:
"Our commitment to Climate Friendly Travel is even more important in a world where we need to plan our post-COVID19 future to also respond to the existential Climate Crisis – the effects of which are already upon us. Malta is a strong supporter of the Paris Climate Agreement and the EU Green Deal: through our work with SUNx Malta we will help bring Travel & Tourism to the table."
Gloria Guevarra, President & CEO, WTTC said:
"This is another important step, working with SUNx Malta to encourage the Travel & Tourism sector to support the Paris Climate Agreement, in line with our long-standing engagement with UNFCCC to achieve Climate Neutrality by 2050. The present COVID-19 crisis has highlighted more than ever, the importance of ensuring sustainable Travel & Tourism as a key enabler to future recovery and growth. WTTC members are committed to play a leadership role."
For SUNx Malta Professor Geoffrey Lipman, its President, and Leslie Vella, Chairman:
"We will provide support tools, underpinning the Registry and train young smart graduates, together with the Institute of Tourism Studies, Malta (ITS), to assist in strategic low carbon transformation. We are proud to work with a growing number of SDG-17 Partners to share innovation, strategic planning, visibility, education and training.
In addition to WTTC, other partners included in the launch include the Ministry for Tourism and Consumer Protection, Malta Tourism Authority, Institute of Tourism Studies, Sustainable First, Green Travel Maps, Mekong Tourism Coordinating Office, and LUX* Hotels & Resorts.
For more details please see
The Strong Universal Network SUNx is a program of the EU-based, not for profit Green Growth and Travelism Institute, and a legacy to the late Maurice Strong – Sustainable Development Pioneer. Its goal is to promote Climate Friendly Travel with good & bad effects measured and managed coherently: with Green Growth at the core and, 2050-proof in line with the Paris Accords, and the W.E.F. 4th Industrial Revolution.
Olly Wheatcroft, SUNx Program Manager,
olly@thesunprogram.com +44 (0) 7765 132408
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By Kayla Henson on Dec 6, 2018 at 12:33 p.m.
North Dakota's eight Regional Human Services Centers must attain national accreditation by July 31, 2021 to be licensed and continue providing services, per Senate Bill 2039, which amends section 50-06-05.2 of the North Dakota Century Code.
These centers--located in Dickinson, Williston, Minot, Bismarck, Devil's Lake, Jamestown, Grand Forks and Fargo--provide a variety of behavioral health services including therapy, addition and psychiatric services.
Previous to the amendment, the centers were only licensed by the state. Jeff Stenseth, Chief Operating Officer, Statewide Clinic Services, North Dakota Department of Human Services, said the move increases standards for the state's behavioral health services.
"Licensing kind of sets the minimum standards, so that's the bar you have to reach to make sure you're providing adequate service," Stenseth said. "Accreditation really goes a little bit deeper and has standards set in all kinds of areas of client care that really is trying to maximize the services that we provide... It sets the bar higher, and it challenges the organization to meet those areas."
DHS' Field Services division is looking for one accrediting body to accredit each center individually rather than seeking accreditation that encompasses all of them.
"Each center ... provides different types of services, so as we seek accreditation for different program levels, it would be a little more difficult to do it as a larger system," Stenseth said.
About two weeks ago, the soliciting window for an accrediting body closed, and they had no bids.
"When the initial request for proposal (RFP) was drafted, we had a lot of specific activities that were listed in it," Stenseth said. "That's where we got a lot of the questions. Now, we really went through it with a fine-tooth comb and have taken a lot of those and rewrote them so that they're more general in nature."
They hope to open up the bids with a revised RFP within the next two weeks.
Their ideal organization would be one that is nationally recognized and has years of experience accrediting these types of institutions.
"We provide a pretty broad continuum (of services)," Stenseth said. "We want to make sure that organization is used to accrediting programs that have multi-levels of service."
Once the organization is selected, DHS might focus on first accrediting a smaller region--Jamestown--and a larger region--Fargo.
"A lot of our policies and procedures will be consistent from region to region so any kind of changes we'd have to make to those... we could learn from the first go around and make those modifications," Stenseth said.
Once accredited, the length of accreditation varies.
"If you do really well in your first survey, you could get anywhere from a two-to-four year accreditation," he said. "If you still have work to do to improve to meet more of their standards, it appears that typically you get a one year accreditation, and then they'll come back the following year and see if you've improved upon the things that you're setting out to improve upon."


The AMA0750 Wall Light is finished in a Polished Chrome colour and is a switched product (Rocker Switch located on the product itself) The height of this particular lighting product is 10cm. It has a depth of 12cm & a width of 20cm. The AMA0750 is designed to use Edison screw cap bulbs (E27 - ES) (Requires 1 x 60w GLS - Traditional Household shaped bulb). This light is F-Rated, which means it can be fitted on flammable surfaces such as wood and has an IP-rating of IP20 (a products IP-rating indicates where in a bathroom or outside it can be installed). The AMA0750 is an earthed lighting product (class 1 light), which means it requires an earth connection in your homes lighting electrics (which most do, however an electrician can verify this or the presence of a green & yellow cable would indicate you do). This is a standard sized product so Lightahome would use a normal, signed for, courier for delivery. (Notable features: wall light frame only mirrored backplate complete with led reading light with LED). Though we try and keep availability of all our products good at all times, we sometimes experience out of stock situations. If your order is urgent then please call us on 024 7671 7043 to check (CHRISTMAS & NEW YEAR DELIVERY! Please note that products by this manufacturer are handmade & orders placed in December are not guaranteed to arrive before Christmas. Though some orders may arrive by then it is worth checking with us if your order is urgent).


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Top 10 Largest Diamonds In The World
Diamonds are some of the most sought-after and prized possessions in the world. The discovery of large diamonds is front-page-worthy news that captivates buyers and the public alike. From a diamond believed to be hailing from outer space to a stone discovered by a young girl in a pile of rubble, read below for the top 10 largest diamonds ever discovered.
What Are The Largest Diamonds In The World?
10. Woyie River – 770 carats
9. Millennium Star – 777 carats
8. Koh-i-Noor – 793 carats
7. Constellation – 813 carats
6. Incomparable – 890 carats
5. Star of Sierra Leone – 969 carats
4. Excelsior – 995.2 carats
3. Lesedi La Rona – 1111 carats
2. Cullinan – 3106.75 carats
1. Sergio – 3167 carats
Starting our list of the top 10 largest diamonds in the world is Woyie River. Discovered in 1945, the Woyie River diamond is named after the river in Sierra Leone in which it was found. At the time, the Woyie River Diamond was the largest alluvial diamond in existence.
The diamond was subsequently brought to England, where it was shown to Queen Mary in 1947 and to the public at the British Industries Fair in 1949. The diamond was ultimately cut into 30 pieces, the largest of which is the Victory Diamond, named after the victory of the Allies in WWII shortly after the diamond's discovery. The Victory Diamond is a 31.35-carat D-color, VVS2 clarity gemstone purchased by investor Frank Gould for his wife Florence in the mid-1900s.
Originally found in the Mbuji-Mayi mine of the Democratic Republic of Congo in 1990, the Millennium Star was a whopping 777 carats uncut. Purchased by De Beers, the rough diamond was cut by the Steinmetz Group to form a 203.04-carat, D-Flawless pear-shaped diamond.
The diamond took three years to cut. In addition to the large pear-shaped diamond, a heart-shaped, 27.64-carat fancy vivid blue diamond and 11 blue diamonds equaling 118 carats were also cut.
One of the most notorious diamonds in history, the Koh-i-Noor diamond dates back to the 13th century at least, when it was reportedly discovered in the Kollur Mine in India. The diamond stayed in the hands of the ruling Kakatiya dynasty for some time, ultimately passing from one succeeding dynasty to the next. The diamond traded hands between various Sikh, Mughal, and Persian rulers who fought over it.
In 1849, Queen Victoria obtained the diamond after the Second Anglo-Sikh War between the Sikh Empire and the British East India Company. The East India Company's victory resulted in the diamond being turned over to the British Empire. In 1852, Prince Albert demanded the diamond be cut, resulting in a 186-carat oval-cut diamond. The diamond remains in the property of the British crown today.
Unearthed in 2015 in the Karowe Mine of Botswana, this 813-carat diamond was originally mined and owned by the Lucara Diamond Corp. After trading hands a few times, the diamond was purchased by De Beers, who sold it to the Zale Corporation.
In a widely publicized sale in 2016, the diamond was purchased by Dubai firm Nemesis International DMCC for a record-setting $63.1 million, making the diamond worth $77,649 per carat. The company has future plans to reshape the diamond.
One of the world's largest diamonds was discovered in 1989 by a young girl who was playing in a pile of rubble in the Democratic Republic of Congo. It took four years for experts to analyze and finally cut the diamond, ultimately choosing to cut a smaller flawless diamond as opposed to retaining a larger size but with more inclusions. The resulting 407.78-carat, Fancy Deep Brownish Yellow, internally flawless diamond set a Guinness World Record when it was valued at $55 million.
The fifth largest diamond in the world was found in 1972 in the Diminco mine in Sierra Leone. The diamond was initially purchased for approximately $2.5 million by jeweler Harry Winston, who cut the diamond in a 143.2 emerald-cut gem. When an internal flaw was noticed, the diamond was recut into 17 smaller pieces, the largest being a 53.96 pear-shaped diamond.
4. Excelsior Diamond – 995.2 carats
The Excelsior diamond was the largest diamond in the world until the discovery of the Cullinan diamond. The stone was found by a working in 1893 in the Jagersontein mine in South Africa. Because the diamond was so large and flawless, it became difficult to find a buyer.
Ultimately, in 1904, the diamond was sent to expert I. J. Asscher of Amsterdam, who cut it into ten smaller stones. The largest gem is a pear-shaped gem weighing 69.69 carats.
One of the most recently discovered large diamond, the Lesedi La Rona was unearthed in 2015 in the Karowe Mine in Botswana. In June of 2016, the rough diamond failed to find a buyer at a Sotheby's auction, likely due to its large size. It is expected to be sold privately.
2. Cullinan Diamond – 3106.75 carats
Found by Sir Thomas Cullinan at the Premier Mine in South Africa in 1905, the Cullinan Diamond was presented to King Edward VII shortly after its discovery. The diamond was cut into 96 small gems and 9 large gems, including the Cullinan I (also known as the Great Star of Africa), a 530.4-carat stone. The Cullinan I is set in the Sovereign's Sceptre with Cross, an important part of the British Crown Jewels.
Topping the list of the top 10 largest diamonds in the world is Sergio. This black carbonado diamond, the largest rough diamond in the world, was found in 1895 in Bahia, Brazil. Carbonados are very rare and are the most durable form of diamond. They often resemble carbon in their natural form.
Some experts believe this rough stone hails from space, a fragment of a supernova that occurred 3.8 billion years ago and landed on Earth 2.3 billion years ago. For more about expensive jewels and famous diamonds, read our ranking of the Top 10 Most Expensive Items of Jewelry in the World.
How To Sell Or Upgrade Your Diamonds Or Jewelry
WP Diamonds offers a free, secure service for selling your diamonds, designer jewelry, and luxury watches online. To receive your price quote, fill out the online form and a member of our team will be in touch with your estimate. Once you receive a final price, you can choose to get paid by check, wire or store credit for a higher final price. Receive up to 10% more when you accept your offer in store credit.
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← Where Are Diamonds Mined? Top Diamond Producing Countries
How To Upgrade An Engagement Ring →

redpajama_set_name: RedPajamaCommonCrawl


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Senator Wants Free Blood Testing For People In Wisconsin PFAS Zone
WXPR | By Ben Meyer
A Wisconsin state senator believes people living in at least one PFAS contamination area should get free blood testing for the compounds.
He would also be open to expanding the testing to other areas of concern.
Sen. Dave Hansen (D-Green Bay) wants the state to approve free PFAS blood testing for people living in the Marinette and Peshtigo areas. Companies have used the area as a testing and training zone for fire-fighting foam, a known source of PFAS.
That family of compounds has been linked to health risks like cancer, thyroid problems, and high cholesterol.
"What has not been discussed is the ability for us to allow people to get free blood tests for people living in or near the PFAS contamination area. That's what we're asking from [Department of Health Services Secretary Andrea] Palm to provide us," Hansen said.
Hansen wants the companies to pay for the testing.
"The stories we've heard have just been awful. Something happened. It seems like the people in power, the responsible party, has been neglectful. What we can to do try to help people and their health is what we're after here," he said.
Hansen would also be open to providing free blood testing in other parts of the state with PFAS contamination concerns, like Rhinelander.
"I'd be agreeable to that, but first things first, we've got to try to get Marinette and Peshtigo moving, and hopefully find enough funding to look at the problem they're finding in Milwaukee," he said. "I know in Madison, they're seeing more and more PFAS contamination."
Hansen's request was made last week to Palm, and has received no response.
Local NewsPFAS
email Ben
See stories by Ben Meyer
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Nearly two months ago, the DNR recommended the City of Rhinelander make full PFAS testing results available on the city's website.As of Thursday…


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Amosun Making Empty Threats, Playing Dirty Politics – Dapo Abiodun Fires
Governor Dapo Abiodun of Ogun State has berated his predecessor, Senator Ibikunle Amoosun, for openly declaring support for his opponent.
Recall that Amosun had last Friday declared his support for the governorship candidate of the African Democratic Congress (ADC), Biyi Otegbeye, in next year's election. Amosun announced his controversial decision despite his support for the presidential candidate of the All Progressives Congress, Bola Tinubu. The lawmaker disclosed that he would be supporting Tinubu in 2023, but would not support the state Governor, Dapo Abiodun who is the governorship candidate of the party. Amosun during an interview with BBC Yoruba, in Abeokuta, Ogun State said, "For the presidential poll, I can assure you, both right, left and centre, we are supporting one person (Tinubu). I believe we are supporting one person. On the governorship poll, that's a different ball game. I don't belong there. "I don't hide behind one finger to fight. That's why people say to me 'don't say that.' On governorship, my supporters and I, we don't belong to that side." Amosun when asked about the governorship candidate he would be supporting in 2023, said, "Biyi Otegbeye is the person I am supporting and ADC is the party." Reacting to Amosun's open declaration during a meeting with members of the Nigeria Automobile Technicians Association, held at the June 12 Cultural Centre, Abeokuta, Dapo Abiodun said the former governor will fail in his anti-party politics aimed to scuttle his re-election bid. According to Abiodun, Amosun will fail once again as he did in the 2019 gubernatorial election. He said the lawmaker's position was an "empty threat of a fallen man", adding that his second term is already ordained by God. The governor noted that it was a pity that Amosun had quickly forgotten how his adopted candidate "lost woefully" during the last general election, even when he was still in office as Ogun Governor. Abiodun said he will not lose sleep over his predecessor's "empty threat", as similar threat in 2019 did not amount to anything, "The same thing that person did in 2019 and failed woefully, even when he was still the governor in the state, he is now preparing to fail again and even fall down. "We are waving goodbye to him now. He is not even a candidate of any political party. He is nothing and he is saying he will stop a governor that God has ordained; he will definitely fail again by the grace of God," The PUNCH quoted Abiodun as saying.
This article was originally published on Naija News
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Buhari's Successor To Inherit N39.12tn Debt


text:
<?php

class Vtiger_Boolean_UIType extends Vtiger_Base_UIType {

	/**
	 * Function to get the Template name for the current UI Type object
	 * @return <String> - Template Name
	 */
	public function getTemplateName() {
		return 'uitypes/Boolean.tpl';
	}

	/**
	 * Function to get the Display Value, for the current field type with given DB Insert Value
	 * @param <Object> $value
	 * @return <Object>
	 */
	public function getDisplayValue($value, $record = false, $recordInstance = false) {
		if($value == 1 || $value == '1' || strtolower($value) == 'on') {
			return Vtiger_Language_Handler::getTranslatedString('LBL_YES', $this->get('field')->getModuleName());
		}
		return Vtiger_Language_Handler::getTranslatedString('LBL_NO', $this->get('field')->getModuleName());
	}

     public function getListSearchTemplateName() {
        return 'uitypes/BooleanFieldSearchView.tpl';
    }

}

redpajama_set_name: RedPajamaGithub


Constructed from a nylon-spandex blend, the Tactile Luxe Sock is perfect for low-impact activities and for athletes and fitness enthusiasts looking for a great, basic ped sock. Despite its basic feel, it features arch support, ventilation, and Y-heel design in a lightweight and soft fabrication. Sizes S-L.
Wow, these are great socks.


text:
import Sequelize from 'sequelize';
import sequelize from '../services/sequelize';

export const Model = sequelize.define('token', {
  user: {
    type: Sequelize.INTEGER,
    references: {
      model: 'users',
      key: 'id',
    },
  },
  token: {
    type: Sequelize.STRING,
  },
});

export default {
  async create(userId, token) {
    const instance = Model.build({
      user: userId,
      token,
    });
    return instance.save();
  },
  async get(token) {
    return Model.findOne({
      where: {
        token,
      },
    });
  },
};


text:
Q: Object gets duplicated inside array This is the result I want to achieve
dataset: [
    dataset: [
        {
            seriesname: "",
            data: [
                {
                    value: "123",
                },
                {
                    value: "123",
                },
            ]
        },
    ]
]

My problem right now is that the second dataset gets duplicated.
This is how I am setting it (val is an integer and allYears is an array of integers):
this.grphColumn.dataSource.dataset[0].dataset = this.allYears.map(el => {
    return {
        seriesname: "Planned",
        data: [{value: val}, {value: val}]
    }
});

How can I make it so the dataset doesn't get duplicated?

A: You have to map the values separately, if you dont want the seriesName to be Repeated..
const yearsMap = this.allYears.map((el) => { return { value: el } });

this.grphColumn.dataSource.dataset[0].dataset = {
        seriesname: "Planned",
        data: yearsMap
    }

redpajama_set_name: RedPajamaStackExchange


Ways to reach a divorce settlement | Stange Law Firm, P.C.
While litigation is a viable option when finalizing a divorce, this is not the only way to obtain a fair and workable divorce decree. In fact, settling out of court not only helps a couple save money in most cases, it also has the tendency of arriving at a quicker resolution.
Alternative dispute resolutions, such as negotiation, mediation, collaboration and arbitration, are all valid and effective ways to achieve a divorce. These methods rely on formal negotiations first. The focus remains on the divorce issues of that particular couples, helping them resolve each one in a fair and timely manner.
In some cases, certain divorce issues just cannot be agreed upon. In these matters, a couple can transition to court to settle on those matters. Anything decided on during an alternative dispute resolution method will remain, even if litigation is the method used to finally reach a divorce settlement.
No matter what divorce method or methods you use, there are options for each and every couple. There is no one size fits all divorce; thus, it is important that divorcing couples are aware of the legal options available to them. This can help them protect their rights as they move forward with the divorce process.


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You are here: Home / Politics / Osborne refuses to assess impact of cuts on disabled people… then slashes their benefits
Osborne refuses to assess impact of cuts on disabled people… then slashes their benefits
By John Pring on 10th July 2015 Category: Politics
The chancellor, George Osborne, has refused to make any attempt to assess the overall impact on disabled people of his budget – and his next spending review – despite being urged to do so by the equality watchdog.
His refusal was confirmed by a senior civil servant just as Osborne was preparing to deliver a budget seen by many campaigners as another attack on disabled people's living standards, in which he slashed future support for hundreds of thousands of people on out-of-work disability benefits.
Only last week, Disability News Service (DNS) revealed government figures which showed that disability poverty rose sharply in the fourth year of the coalition government.
Last summer, the Equality and Human Rights Commission (EHRC) published a report that concluded that assessing the overall impact of welfare reforms and spending cuts on disabled people was "feasible and practicable", despite ministers repeatedly claiming such a task was impossible.
The report also concluded that disabled people had been hit disproportionately hard by the government's welfare reforms.
The report was part of work the EHRC was doing with the Treasury and other government departments – including the Department for Work and Pensions – to examine ways of "making financial policy fairer and more efficiently targeted".
Disabled activists and other campaigners have been demanding since at least 2011 that the government carries out a "cumulative" assessment of the impact of its spending and benefit cuts and other welfare reforms on disabled people.
But work and pensions ministers under the coalition repeatedly ridiculed the idea, even though their own social security advisory committee said it could and should be done.
Now, in the first evidence session of a committee set up by the House of Lords to examine the impact of the Equality Act 2010 on disabled people, a senior civil servant has admitted that attempts to persuade Osborne to carry out such an assessment have failed.
The admission came on Tuesday, less than 24 hours before the chancellor delivered his budget speech.
The disabled peer Baroness [Sal] Brinton (pictured), president of the Liberal Democrats, had asked the panel of senior civil servants if it was possible to see a Treasury assessment of the cumulative impact on disabled people of "a whole string" of cuts to their support, such as the closure of the Independent Living Fund, and the introduction of the bedroom tax and benefit caps.
But Charles Ramsden, head of the equality framework team for the Government Equalities Office, told her that the Treasury "does not accept the scope for doing cumulative impacts across government", and that "agreement on that important area and one or two other points has not been reached finally".
An EHRC spokesman told DNS today (Thursday): "During the last few years, the commission has influenced the work of HM Treasury and key central government departments to improve the way that equality considerations are taken into account in financial decision-making.
"Earlier this year, we published a report which recommended the steps the government should take to ensure budget and spending review decisions are as fair as possible."
These steps included assessing the combined effects on different groups, such as disabled people, of a range of spending decisions, he said.
He added: "We will maintain a watching brief on the work by the Treasury to continue these improvements, including in the context of the 2015 spending review later this year."
But he has so far refused to confirm that discussions with the Treasury have now concluded, and that the Treasury has refused to carry out a CIA, despite Ramsden's comments.
The Treasury said it was "fully compliant" with its public sector equality duties when taking policy decisions, which included "considering the impact of measures on people with disabilities and if any mitigating action is appropriate".
A Treasury spokeswoman said: "We have completed assessment of all individual measures in line with our statutory duties."
But she later admitted that the Treasury would not be carrying out any cumulative assessments.
She said: "We can't do a cumulative technical assessment because we don't have the modelling capability to do so.
"The survey which underpins our model doesn't contain enough information on disabled people to do a robust qualitative assessment."
Meanwhile, in a blog by the commission's chair, Baroness Onora O'Neill, published on Sunday (5 July), she warns that one of the "big themes" of Is Britain Fairer?, the EHRC's five-yearly report on progress towards equality and human rights, due later this year, was "likely to be about life in Britain in 2015 for many disabled people, and their opportunities to participate in our society".
She says in the blog: "The data shows concerns in a number of different areas, including participation in the labour market and some aspects of care and support for people with severe disabilities."
Tags: cumulative impact assessment EHRC George Osborne Treasury
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Minister told by human rights experts to end unacceptable education opt-out
Tomlinson held just a handful of external meetings every month early in pandemic
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Minister allows transport industry its fourth exemption from access laws
Government's pandemic failings caused us 'horrendous' challenges, say DPOs
Watchdog has approved care settings for COVID patients in only three-fifths of areas
High court is asked to order fresh inquest into death of Jodey Whiting
MPs call for inquiry into government's role in COVID deaths of disabled people


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When It Comes to Parenting Their Black Children, These White Dads Definitely See Color — And They Think Others Should, Too
Rob and Reece Scheer talk to Shondaland about being featured in the Apple TV+ documentary "Dads," and why being "colorblind" is actually harmful to their children.
By Mekeisha Madden Toby
The Scheer Family/Apple TV+
Amaya, Makai, Greyson and Tristan Scheer discuss the best ways to navigate the world as Black kids with their parents all the time. Yes, it's tragic that moms and dads still have to have "the talk" — the one about race, not sex — to ensure the survival of their Black progeny. But the fact of the matter is Black kids are profiled (by law enforcement, private security officers, and school resource officers) more than kids from other races, and police brutality is the sixth leading cause of death for young Black men in America.
We don't want our kids to go through life with rose-colored glasses, thinking that America doesn't have a race problem.
"It's there and we have to talk about it," Rob Scheer tells Shondaland, regarding the very honest exchanges he and his husband, Reece Scheer, have with their children on a continuous basis. "And we're sorry we have to say things to our children like, 'You can't wear your hoodie. Keep your hands out of your pockets. And if the police ever pull us over, immediately put your hands on the dashboard.'"
Black parents have been facilitating talks like this with their kids for centuries. But what makes Rob and Reece Scheer unique is that they are two white men mindfully raising a household full of young Black children.
"These are the conversations that we must have, because we must protect our children," Rob Scheer says. "We don't want our kids to go through life with rose-colored glasses, thinking that America doesn't have a race problem. We have a major problem because society treats our kids differently because of their skin color."
The Scheers, who live in Darnestown, Maryland, are two of the six everyday fathers featured on the new Apple TV+ documentary Dads. The film — which hit the streaming service just before Father's Day and marks actress Bryce Dallas Howards' directorial debut — celebrates patriarchs like the Scheers as well as celebrity fathers such as Will Smith, Jimmy Kimmel, Conan O'Brien, Hasan Minhaj, Kenan Thompson, Patton Oswalt and more. Howard also interviews her famous father, actor-turned-filmmaker Ron Howard, his dad Rance Howard (shortly before his death), and her younger brother, Reed Howard, who became a father last year.
Dads is also premiering during a time of great social upheaval, where the heartbreaking murders of George Floyd, Breonna Taylor and Rayshard Brooks at the hands of the police have caused countless protests and racially-inspired cultural shifts all over the world.
"I cannot teach my children how to be Black or teach them how to be white, but I can teach them how to be good humans," says Rob Scheer. His brood consists of five children of color — Alex, 19, who's biracial; Amaya, 16, and her 13-year-old her biological brother Makai; and biological siblings Greyson,13, and Tristan, 11, who are Black.
"From the day our children arrived, we've always had to have 'the talk.' Most white parents have no idea. I'm a white privileged male. When I walk into Nordstrom, they want to know what my credit score is. When my son Greyson, who is 13 years old and wears a size 12 shoe walks into Nordstrom with his hoodie on, they want to know is he going to steal."
Rob and Reece Scheer know they can't love racism away, but they are trying to give all of their children a better chance by making sure they excel academically and someday professionally.
"It's something we have to educate them about and the only way we're going to ever close that racial gap — and it will [probably] never be closed — is education," Rob Scheer says.
"The key to success is education. My husband and I say this all the time. We tell our kids they have one job from the moment they live with us until the day they graduate from college — they have to get an education," says Rob Scheer, who grew up in the foster care system and has a successful career in banking. "Their father and I will take care of them and get them anything they need. Just please, please get an education. That's how we make our world better."
The Scheer family.
Making matters slightly more complicated is the fact that Makai Scheer is a special needs teenager fighting to overcome Fetal Alcohol Syndrome (FAS), a sensory processing disorder and Attention Deficit Disorder. Studies show that Black and brown young people with disabilities are 13 percent more likely to be arrested than those who don't have them. But the Scheers aren't deterred by the statistics.
Despite the odds, Makai is thriving because Reece Scheer gave up his day job to become a stay-at-home dad, and his parents enrolled him in a very forward-thinking school. They also moved to a farm after Reece Scheer learned that farm animals can help kids with FAS with much-needed frontal lobe development.
"We wanted to give him the best life possible," Reece Scheer says. "We researched and found out how well people with these disorders do around animals and things like that. Everybody can have a dog or a cat but we wanted to take it further and give Makai a farm."
But Makai can't stay on the farm 24/7 and trying to explain racial bias to him has been challenging, his fathers say.
"He wears his hoodie continuously and it's not even because he's cold," Reece Scheer explains. "The hood gives him a sense of security. We try to teach him that there are places he can wear his hoodie and that there are places he shouldn't. Trying to teach him those skills is hard.
Other white people will come up to us and say, 'Your family is so beautiful. We don't see color' and I'm like, well, you don't see our kids.
There was also a near-encounter with the police while on vacation in South Carolina that rattled everyone's nerves.
"Some white onlookers saw Makai, a Black boy on a bike, riding on the steps of the church and thought that they needed to call the cops to come deal with him," Reece Scheer says. "And I ended up having to step in to let them know that Makai has special needs. We've also had to teach him that he can't approach people in any type of aggressive way. It's things like that that are scary because he doesn't always understand. But we do our best in order to give him the life skills that he needs to be safe and successful."
Makai happily approaches strangers oftentimes because he's curious and a little awkward. When he did this as a little kid, most strangers thought it was cute. Now that he's 13 and tall, some folks find him threatening. Although this is a societal stereotype parents have to address before their Black sons even reach their teen years, the issue becomes more contentious when dealing with a child with special needs.
"It is very scary. Makai is tall. He's dark complexioned. He approaches everyone because he's a happy boy," Rob Scheer says. "Instead, some people overreact and freak out. I read something the other day that made me question when society started looking at him as a threat."
Rob and Reece Scheer recall taking a two-year-old Makai to a White House Easter Egg Roll during the Obama administration — and just how quickly perceptions of his son have changed.
"President Obama was standing in front of Makai and he tugged Makai's ear and said, 'You have ears just like mine. You are so cute,"' Rob Scheer says. "When did human beings start looking at Makai not as a cute, big eared boy but someone who is dangerous? I look at him and I still see my bright eyed, big eared baby with a super adorable smile."
"We are better humans because of Makai," Rob Scheer continues. "He's taught us how to look at the world upside down too. That whole narrative that a Black boy turns 12 and becomes dangerous is scary, unfair and untrue. But it literally happens overnight. As a parent it keeps us up at night because these are our babies."
Most of all, these two loving and progressive fathers want the world to embrace and love their children the way they do. Until that happens, Rob and Reece Scheer vow to stand by their kids and teach them how to triumph despite the obstacles of systemic racism.
"Other white people will come up to us and say, 'Your family is so beautiful. We don't see color' and I'm like, well, you don't see our kids," Rob Scheer explains. "If you don't see color, you are not looking at our children. The moment that you accept that they are here, and they are Black, then maybe we can move forward."
"They are beautiful and the world should never make them feel like it's scared of them," Rob Scheer surmises. "We are all so different throughout our country. But we are very much the same because we all want our children to do better than us and have a world that is better than ours."
Dads premieres Friday June 19 on Apple TV+
Mekeisha Madden Toby is a Los Angeles-based TV critic, editor, and entertainment journalist. Follow her on Twitter @mekeishamadto.
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text:
Gedling Access Road
Nottinghamshire County Council have been safeguarding proposals for a Gedling village bypass for over 50 years, and GAR forms part of the proposals for the A612 Nottingham Eastern Outer Loop Road. This has, with the exception of the eastern most section around Gedling village, been successfully completed by the Council. GAR will connect directly to the most recently constructed phase (the Gedling Major Integrated Transport Scheme) which opened to traffic in 2007.
The Gedling Access Road (GAR) was granted planning permission by Gedling Borough Council (GBC) on 23 December 2014, subject to 22 planning conditions. Condition 2 of the Original Permission was varied by application under section 73 of the Town and Country Planning Act 1990, granted reference 2015/0110. The variation was required to amend reference to approved plans and was granted permission on 26 February 2015.
Subsequently the GAR Permission was granted consent on 3 June 2016, reference 2015/1033. The GAR Permission is the consent that will be implemented to deliver the new road and applications to discharge pre-commencement planning conditions have been submitted to GBC and approved in December 2017. Confirmation of the commencement of development was made in December 2017 with the start of advanced drainage works around the perimeter of Gedling Country Park.
Application 2014/0915 - Construction of a 3.8km long road linking A612 Burton Road and B684 Mapperley Plains Road (Gedling Access Road)
Application 2015/0110 – Application to vary Condition 2 to allow limited vegetation clearance for gas main re-alignment
Application 2015/1033 – Application to vary Condition 1 to enable the continuous construction of the road with a simultaneous end date for Phase 1 and Phase 2
Application 2017/153DOC – Application for approval of details reserved by condition, numbers 10, 16, 17 ,18 and 19.
Aims and benefits
Compulsory Purchase Order and Side Roads Order


text:
Woman of the Month: Katsuko Saruhashi
March 30, 2018 April 1, 2018 ~ Ally Writes Things
Woman of the Month is a feature on my blog where each month I highlight a woman in the world who I think garners recognition. I started this mainly to increase Girl Power and empowerment, and because there's a lot of women I feel are overlooked and I wanted to bring attention to them.
This month I'm highlighting Katsuko Saruhashi.
Katsuko Saruhashi
Katsuko Saruhashi was a Japanese scientist who developed a technique that allowed her to measure the CO2 levels of sea water. Her team was the first to demonstrate the influence of radioactive fallout and how it can travel far distances. Her developments in this field helped a lot of the nuclear cleanup after WW2.
She established the Society of Japanese Women Scientists and the Saruhashi Prize, a prize given yearly to a female scientist who serves as a role model for younger women scientists. She was the first woman elected to the Science Council of Japan. She was also the first woman to earn a doctorate in chemistry, not just from the University of Tokyo, but in all of Japan.
This quote from her really sums up how I feel about women in the STEM field.
There are many women who have the ability to become great scientists. I would like to see the day when women can contribute to science and technology on an equal footing with men.
Thanks for reading! xx
Posted in books, Uncategorized, Woman of the Month	feminismjapanrole modelssexismSTEMstrong womentechnologyWoman of the Monthwomenwomen in STEM
Published by Ally Writes Things
I like books and talking about my opinions.	View all posts by Ally Writes Things
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5 thoughts on "Woman of the Month: Katsuko Saruhashi"
Awesome! I love this series of yours, and I think you're doing a great job of highlighting women of all kinds — they're diverse in both racial and professional background. Very nice job.
Ahhh thank you so much!! I try to make it diverse because it wouldn't be very intersectional of me to only focus on white people
Very true, but a lot of people don't think about that. It's refreshing. 🙂
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It seems that a short piece of pipe, with one end sealed, and the other end with a divider going down about halfway, could make a portable warming/cooking device for use with leaves, twigs, other small combustibles. The idea is, you blow into one side to keep the coals, which are concentrated at the sealed end of the pipe, red-hot. That end is what you stick into a water-filled cooking vessel (even plastic), to cook soup or brew coffee. Or you seal the other end and enclose it in some heavy wrapping that can take the heat (a couple of wool socks, one inside the other) for use as a foot-warmer inside your sleeping bag on a cold night.
Still experimenting with my new trailer as a vehicle, with a skateboard on the "handle" end. This time I tried it with the skateboard behind me, and the trailer wheels at my feet. It seems less likely to break the trailer, but it's harder to steer. Maybe the handle needs to be forward of center, so I can more easily lift the back of the skateboard to point in the direction I want to go. Mañana.


When a person gets picked up for a DUI in Nebraska they will typically get some kind of combination of probation, house arrest, jail and heavy fines. But in Sarpy County, things are different.
Folks who get a first-offense DUI can enter a diversion program and wipe their record clean of a drunk driving conviction.
"We see success, we don't see those people coming back, the majority of those folks," says Sarpy County Attorney Lee Palikov.
Longtime Sarpy County Attorney Lee Palikov says his program is effective, and that an internal survey showed that just 5 percent of people that completed DUI diversion re-offend.
"That empirical evidence tells me it's been successful, that's it's an opportunity for people to learn and change their behavior, if they're willing to," says Palikov.
Hundreds of people a year are able to get into this diversion program, with some out of it as soon as six months. It's typically just for first offense drunk driving, but exceptions can be made.
But, not everybody is okay with the county program.
'I think overall it's bad policy," says executive director of Project Extra Mile Chris Wagner.
"A lot of times the folks drinking and driving haven't been caught yet, so they're already doing it regulary."
Wagner, who advocates for the reduction of alcohol-related crimes, says that people who get DUI's typically already have driven drunk many times before and a slap on the wrist like diversion, would not fix the issue.
He also says tactics such as taxing booze and putting liability on alcohol establishments would be better methods for reducing drunk driving.
Still, Polikov stands by his program, saying it allows people to get attention and treatment for alcohol abuse while also saving the county money by staying out of the court system.
"Because it's money better spent in a lot of ways, for the offender and for the community."
Because of this, he hopes the legislature eventually reverses their decision and allows dui diversion statewide.
This diversion law has come back into the public eye recently after former Omaha Fire Chief and current state senator Mike McDonnell was arrested for DUI in Sarpy County . He will likely have the chance to enter that DUI diversion program.


text:
Category: Home > Reviews > Drama > Historical > War > Cable TV > Mini-Series > Fantasy > Action > Epic > Spy > Thriller > Ship > Battles > Br > Catherine The Great (2019/TV Mini-Series*)/Game Of Thrones 4K: The Complete Collection (2011 - 2019/4K Ultra HD Blu-ray Box/*both HBO/Warner)/Killing Eve: Season 3 (2020/Acorn Blu-ray)/Mutiny! (1952/M
Catherine The Great (2019/TV Mini-Series*)/Game Of Thrones 4K: The Complete Collection (2011 - 2019/4K Ultra HD Blu-ray Box/*both HBO/Warner)/Killing Eve: Season 3 (2020/Acorn Blu-ray)/Mutiny! (1952/MVD/VCI Blu-ray)
4K Ultra HD Picture: B+ Picture: C/X/B+/C+ Sound: C+/B+/B+/B- Extras: D/B+/A-/C Main Programs: B-/B+/B+/C+
Next up is a mix of TV programs, a feature film and adventure mostly set in the past...
Though many films and TV shows have been done on the historic title figure, I can see why HBO would make a new Catherine The Great (2019) program, which is what you do when you have a decent script and get no less than Helen Mirren to play the title role. Catherine has shown up in so many productions, including lately and not all have been good. This is one of the better ones.
The production has some money in it and Jason Clarke becomes her opposer over the four episodes we get here that are good without being pretentious or overdone. I have to admit that we have been getting swamped with these costumers, whether fantasy genre entries or historical, but I will say this one does not try so hard to deal with her adult life and history. The look of the shows was nothing extraordinary, but the performances are solid and the supporting cast is just fine.
Philip Martin directed the entire mini-series, something that is actually unusual these days, so that in itself is of note, but Mirren carries this well and those interested should check it out.
There are sadly no extras.
To add to its elaborate Blu-ray editions, then its upgraded Dolby Atmos Blu-rays and the bookending seasons having already being issued in 4K, another landmark. Game Of Thrones 4K: The Complete Collection (2011 - 2019) is the first TV show of any kind to get the 4K treatment in its entirety, meaning it had to be finished and off the air for good, but few TV shows are still not in 4K yet despite the many that qualify.
The show established a new series of stars (even when some left, then went onto more success like Jason Momoa) and showed its exceptional taste by having some of the greatest British actors of all time in its cast like Charles Dance, Julian Glover, Peter Vaughn and Jonathan Pryce among them.
We have covered all eight seasons, sometimes on more than one version, tried not to spoil anything and HBO (as they often have anyhow) went out of their way to offer the best possible sets on the market for any TV show. Here are the Seasons as we covered them in the past...
In 4K
http://www.fulvuedrive-in.com/review/15193/Captain+From+Castille+(1947/Fox/Twilight+Time
http://www.fulvuedrive-in.com/review/11482/Game+of+Thrones:+The+Complete+First+Season
http://www.fulvuedrive-in.com/review/12122/Game+Of+Thrones+%E2%80%93+The+Complete
Blu-ray with Dolby Atmos upgrade
http://www.fulvuedrive-in.com/review/14229/Ballers:+The+Complete+First+Season+(2016/HBO
http://www.fulvuedrive-in.com/review/12596/Game+Of+Thrones:+The+Complete+Third+Season
http://www.fulvuedrive-in.com/review/13318/Game+Of+Thrones:+The+Complete+Fourth+Seaso
http://www.fulvuedrive-in.com/review/14108/Game+Of+Thrones:+The+Complete+Fifth+Season
http://www.fulvuedrive-in.com/review/14557/Game+Of+Thrones:+The+Complete+Sixth+Season
http://www.fulvuedrive-in.com/review/15600/Game+Of+Thrones:+The+Complete+Seventh+Sea
http://www.fulvuedrive-in.com/review/15616/Game+Of+Thrones:+The+Complete+Eighth+Seaso
More on the tech playback below, but even non-fans (like myself) can appreciate how well made this was (despite complaints about the conclusion) and is far and above one of the best fantasy TV shows of all time, like it or not. For me however, the real late highlight was what turned out to be one last great stand of many for one of my all-time favorite actors of all time, international star Diana Rigg. Passing away as we were working on this set, as Lady Olenna Tyrell.
Gracing 18 episodes, she shook up a show that already seemed set on its course, throwing it another curve ball and stunning audiences worldwide. It has been a long time since I had so many people so impressed and ask me 'who is that actress?' as they did on this case, but it amounted to one final triumph for Rigg and the show. Glad she got one last great moment in the sun. I dare say she may have extended the show's life, but fans might say otherwise.
Extras repeat from the original releases, plus extras from the pre-4K Complete set, including...
Game of Thrones: Reunion Special: A two-part reunion show shot live in Belfast with the cast, both past and present, hosted by Conan O'Brien and available exclusively on these complete series collections. The reunion special is assembled in segments focused on Houses Lannister, Stark, & Targaryen and concludes with the key players all onstage for their final reflections on the years they shared in Westeros and Essos.
Game of Thrones: The Last Watch: A documentary by filmmaker Jeanie Finlay chronicling the making of the final season.
Conquest & Rebellion: An Animated History of Seven Kingdoms
and an illustrated booklet with episode guide and extras listings. Some extras are int heir own case of regular Blu-ray discs.
Needless to say this is an elaborate set worth your time and money for fans, as a gift set or to just immerse yourself in the show.
After surviving last season, Eve, former MI6 operative gets out of the secret service/intelligence community. When a close friend dies in a suspicious 'accident', no one believes it was an 'accident', eve once more crosses path with Villanelle and whomever she is connected as the chief suspects for her friend's death. But in a world that is filled with secrets, spies and assassins, who is telling the truth and who is telling the lies?
In Killing Eve: Season 3 (2020), Eve wants to get out of the intelligence agencies... and similarly Villanelle also is considering quitting being an assassin (or at least get a promotion) for the secret society known only as 'The Twelve' (but usually assassins can only quit when they are dead). Both of them are tired of the constant BS, lies, their boss's paranoia (and their inability to show emotions/empathy) and their agencies bureaucratic politics. But can spies and assassins live as normal people? As Eve and Villanelle try to be 'normal' their paths keep crossing one another and they find themselves drawn toward each other (at least they don't have to lie each other) and if it weren't for the fact each of their respective jobs makes them natural enemies ..,would they have been friends? As they try (and fail) to live like normal people, they realize there is no going back and the truth is never as simple it is (or is it?). Jodie Comer and Sandra Oh continue to keep things going as the co-stars, keeping fans happy.
This was a spy vs. spy series with a bit of a twist and drama, where spies and assassins have (and want) a life too. The comedy is how they are so good at their jobs, but completely fail when it comes to family, life or personal relationships. My only wonder is how the 2 main characters they should have picked actresses who were closer age range, because if they wanted to create a (romantic/lesbian?) relationship between the two, their age differences makes it comes off more as like mother and daughter relationship. Extras include The Spice Kill, The Bitter Pill, Meet the Team, Konstanin's World, The Family Home, The Locations, and Dasha and the Psychology of a Killer.
Episodes this time include...
Slowly Slowly Catchy Monkey - Villanelle wants to get promoted in the life of being an assassin so that she is calling the shots, but to do so she must kill more. Eve finds herself pulled back into the world of MI6 when her friend is found dead (who also so happens to be her former boss's son).
Management Sucks - Eve attends her friend's funeral but is sick how everyone says it is an 'accident' when no one believe it was. Villanelle is given a task to train a new assassin, but when he messes up the job, she kills him, later she learns Eve is still alive.
Meetings Have Biscuits - Eve and (former) company teams up together (not out of choice) in an unsanctioned investigation to avenge Kenny's death and Eve has a surprise run in with Villanelle.
Still Got It - Eve begins to investigate on Villanelle's past kills and her signature kills. Dasha nearly kills Eve's ex-husband, to prove to Villanelle she is still the best and to get her back in the game, but everyone suspects it's Villanelle's doing and it's a warning.
Are You from Pinner? - Villanelle returns to her home and family's surprise that she is alive and well. She lives what a 'normal' life is, while she is happy and it is 'normal', she decides she is happier with being an assassin (better to admit she is a monster than a monster trying to pretend she is not) and she blows up her family home.
End of Game - Villanelle gets tired of still being ordered around and decides she wants out and starts formulating a plan with Konstantin. Eve discovers Villanelle is not responsible for the attack on her ex-husband.
Beautiful Monster - Villanelle attacks Dasha and makes her attempt to get out with Konstantin but things go unplanned and she is forced to improvise. Eve is hot on Villanelle's trail.
and Are You Leading or Am I? - Villanelle goes to MI6 and offers to be their informant into the Twelve, but they only want her to be an assassin for MI6 and reject her. Eve discovers her friend's death was truly an accident and fate (and paranoia) seem to have brought her and Villanelle together again. Together they bring out the best and worst in each other, but they still care and are drawn to one another. They stand on a bridge together wondering what the future now holds for them ...and if they ever can be truly together.
Last but not least is Edward Dmytryk's Mutiny! (1952) pitting Mark Stevens and Patrick Knowles somewhat as one man is asked to sneak $10 Million in gold to the U.S. from, France during the War of 1812, but word gets out to some of the crew by accident and also expecting to join the journey is the lady of one of the men (Angela Lansbury!) and the ship is having other issues. War is hell.
For being an independent production of the time (it was distributed by United Artists at the time) in real, full Technicolor and all, it is impressive for tis time and some money did go into the production, but some things aged better than others. Still, the zero presence of bad digital visual effects is more fun and charming than ever, while other set pieces look outright ambitious. Running 78 minutes, it is not bad and worth a look, especially after those Pirates of the Caribbean films got so played out. Lansbury usually steals her scenes too, even if she is not trying.
Extras include a great set of Warner-Pathe newsreels of the time and the Technicolor Popeye animated cartoon short ''Cookin' With Gags'' from the same period, in decent shape, if not up to what Warner Archive has issued from the series.
Now for playback performance. The 2160p HEVC/H.265, Dolby Vision/HDR (10; Ultra HD Premium)-enhanced Ultra High Definition image on the Thrones episodes are pretty much a summation of the two sets we covered before. The first six seasons are all upscales and I like them a bit better, even if they show the limits of the CGI computer-generated effects as weaker than one would like, but it looks more solid to me in 4K than regular Blu-ray. This continues with the final two season, but they also brought in Ultra HD cameras for some sequences and that works very well, making the show look the best it could (outside of shooting on film, which they considered originally, then never did) and the show retains its unique look all the way. It will never look better than it does here.
We can say the same about the sound as all episodes have now been upgraded to Dolby Atmos 11.1 (Dolby TrueHD 7.1 for older systems) mixes and that is good for any action or fantasy release. The later episodes benefit more as more money was going into the show and its sound was improving, but all the upgrades here were worth it.
The anamorphically enhanced 1.78 X 1 image on Catherine is good and passable for the old DVD format, though a bit softer than I would have liked, but the show has a rich look that needs HD and we'll have to see if we get that later. Same for the sound, here in the old, compressed, lossy Dolby Digital 5.1 format, but the soundmaster is obviously richer and deserves lossless treatment. This DVD set is passable at best.
The 1080p 1.78 X 1 digital High Definition image transfers on Eve look as good as the show ever has and is surprisingly well done, which extends to the nice soundfields in the DTS-HD MA (Master Audio) 5.1 lossless mixes on each show. Combined, it is better than you might expect.
The 1080p 1.33 X 1 digital High Definition image transfer on Mutiny is scanned from what is supposed to be the original 35mm camera negative, but since it was shot in dye-transfer, three-strip Technicolor, what happened to the three-strips? Though we get some nice shots and a nice idea at times of how good the color must have been, the color and definition is uneven here and that means the source needs some work. Director of Photography Ernest Laszlo, A.S.C., who was a solid DP all the way to his work on the 1976 hit Logan's Run could always handle a big screen work and this is no exception, making this film even better than it might have otherwise been, yet he also knew how to make actors look good. Nice.
The PCM 2.0 Mono is as good as it will likely get for now and is not bad, with only minor distortion and issues here and there. Dimitri Tiomkin's score is another plus here and is not bad at all, sounding decent here too. Wonder if he recorded these tracks in stereo?
- Nicholas Sheffo and Ricky Chiang (Eve)
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text:
Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity
Tatiana Y. Hargrove, Edward P. Garvey, William J. Hoekstra, Christopher M. Yates, Zdzislaw Wawrzak, Girish Rachakonda, Fernando Villalta, Galina I. Lepesheva*
Within the past few decades, the incidence and complexity of human fungal infections have increased, and therefore, the need for safer and more efficient, broad-spectrum antifungal agents is high. In the study described here, we characterized the new tetrazole-based drug candidate VT-1598 as an inhibitor of sterol 14α-demethylase (CYP51B) from the filamentous fungus Aspergillus fumigatus. VT-1598 displayed a high affinity of binding to the enzyme in solution (dissociation constant, 13 ± 1 nM) and in the reconstituted enzymatic reaction was revealed to have an inhibitory potency stronger than the potencies of all other simultaneously tested antifungal drugs, including fluconazole, voriconazole, ketoconazole, and posaconazole. The X-ray structure of the VT-1598/A. fumigatus CYP51 complex was determined and depicts the distinctive binding mode of the inhibitor in the enzyme active site, suggesting the molecular basis of the improved drug potency and broad-spectrum antifungal activity. These data show the formation of an optimized hydrogen bond between the phenoxymethyl oxygen of VT-1598 and the imidazole ring nitrogen of His374, the CYP51 residue that is highly conserved across fungal pathogens and fungus specific. Comparative structural analysis of A. fumigatus CYP51/voriconazole and Candida albicans CYP51/VT-1161 complexes supports the role of H bonding in fungal CYP51/inhibitor complexes and emphasizes the importance of an optimal distance between this interaction and the inhibitor-heme iron interaction. Cellular experiments using two A. fumigatus strains (strains 32820 and 1022) displayed a direct correlation between the effects of the drugs on CYP51B activity and fungal growth inhibition, indicating the noteworthy anti-A. fumigatus potency of VT-1598 and confirming its promise as a broad-spectrum antifungal agent.
Antimicrobial agents and chemotherapy
https://doi.org/10.1128/AAC.00570-17
Aspergillus fumigatus
Inhibition
Sterol 14α-demethylase (CYP51)
X-ray structure
Dive into the research topics of 'Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity'. Together they form a unique fingerprint.
Lanosterol 14 Alpha-Demethylase Pharmacology, Toxicology and Pharmaceutical Science 100%
drugs INIS 71%
spectra INIS 57%
Spectrum Biochemistry, Genetics and Molecular Biology 57%
Antifungal Agent Pharmacology, Toxicology and Pharmaceutical Science 42%
interactions INIS 28%
strains INIS 28%
enzymes INIS 28%
Hargrove, T. Y., Garvey, E. P., Hoekstra, W. J., Yates, C. M., Wawrzak, Z., Rachakonda, G., Villalta, F., & Lepesheva, G. I. (2017). Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity. Antimicrobial agents and chemotherapy, 61(7), [e00570-17]. https://doi.org/10.1128/AAC.00570-17
Hargrove, Tatiana Y. ; Garvey, Edward P. ; Hoekstra, William J. et al. / Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity. In: Antimicrobial agents and chemotherapy. 2017 ; Vol. 61, No. 7.
@article{a3f3155dad5c430fb50b9a17ad6af732,
title = "Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity",
abstract = "Within the past few decades, the incidence and complexity of human fungal infections have increased, and therefore, the need for safer and more efficient, broad-spectrum antifungal agents is high. In the study described here, we characterized the new tetrazole-based drug candidate VT-1598 as an inhibitor of sterol 14α-demethylase (CYP51B) from the filamentous fungus Aspergillus fumigatus. VT-1598 displayed a high affinity of binding to the enzyme in solution (dissociation constant, 13 ± 1 nM) and in the reconstituted enzymatic reaction was revealed to have an inhibitory potency stronger than the potencies of all other simultaneously tested antifungal drugs, including fluconazole, voriconazole, ketoconazole, and posaconazole. The X-ray structure of the VT-1598/A. fumigatus CYP51 complex was determined and depicts the distinctive binding mode of the inhibitor in the enzyme active site, suggesting the molecular basis of the improved drug potency and broad-spectrum antifungal activity. These data show the formation of an optimized hydrogen bond between the phenoxymethyl oxygen of VT-1598 and the imidazole ring nitrogen of His374, the CYP51 residue that is highly conserved across fungal pathogens and fungus specific. Comparative structural analysis of A. fumigatus CYP51/voriconazole and Candida albicans CYP51/VT-1161 complexes supports the role of H bonding in fungal CYP51/inhibitor complexes and emphasizes the importance of an optimal distance between this interaction and the inhibitor-heme iron interaction. Cellular experiments using two A. fumigatus strains (strains 32820 and 1022) displayed a direct correlation between the effects of the drugs on CYP51B activity and fungal growth inhibition, indicating the noteworthy anti-A. fumigatus potency of VT-1598 and confirming its promise as a broad-spectrum antifungal agent.",
keywords = "Aspergillus fumigatus, Fungal infections, Inhibition, Sterol 14α-demethylase (CYP51), VT-1598, X-ray structure",
author = "Hargrove, {Tatiana Y.} and Garvey, {Edward P.} and Hoekstra, {William J.} and Yates, {Christopher M.} and Zdzislaw Wawrzak and Girish Rachakonda and Fernando Villalta and Lepesheva, {Galina I.}",
note = "Funding Information: This work was supported by Viamet Pharmaceuticals, Inc. (Durham, NC), and by National Institutes of Health grant R01 GM067871 (to G.I.L.). Vanderbilt University is a member institution of the Life Sciences Collaborative Access Team at Sector 21 of the Advanced Photon Source (Argonne, IL). Use of the Advanced Photon Source at Argonne National Laboratory was supported by the United States Department of Energy, Office of Science, Office of Basic Energy Sciences, under contract DE-AC02-06CH11357. Use of LS-CAT Sector 21 was supported by the Michigan Economic Development Corporation and the Michigan Technology Tri-Corridor (grant 085P1000817). Publisher Copyright: Copyright {\textcopyright} 2017 American Society for Microbiology. All Rights Reserved.",
doi = "10.1128/AAC.00570-17",
journal = "Antimicrobial Agents and Chemotherapy",
publisher = "American Society for Microbiology",
Hargrove, TY, Garvey, EP, Hoekstra, WJ, Yates, CM, Wawrzak, Z, Rachakonda, G, Villalta, F & Lepesheva, GI 2017, 'Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity', Antimicrobial agents and chemotherapy, vol. 61, no. 7, e00570-17. https://doi.org/10.1128/AAC.00570-17
Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity. / Hargrove, Tatiana Y.; Garvey, Edward P.; Hoekstra, William J. et al.
In: Antimicrobial agents and chemotherapy, Vol. 61, No. 7, e00570-17, 07.2017.
T1 - Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity
AU - Hargrove, Tatiana Y.
AU - Garvey, Edward P.
AU - Hoekstra, William J.
AU - Yates, Christopher M.
AU - Wawrzak, Zdzislaw
AU - Rachakonda, Girish
AU - Villalta, Fernando
AU - Lepesheva, Galina I.
N1 - Funding Information: This work was supported by Viamet Pharmaceuticals, Inc. (Durham, NC), and by National Institutes of Health grant R01 GM067871 (to G.I.L.). Vanderbilt University is a member institution of the Life Sciences Collaborative Access Team at Sector 21 of the Advanced Photon Source (Argonne, IL). Use of the Advanced Photon Source at Argonne National Laboratory was supported by the United States Department of Energy, Office of Science, Office of Basic Energy Sciences, under contract DE-AC02-06CH11357. Use of LS-CAT Sector 21 was supported by the Michigan Economic Development Corporation and the Michigan Technology Tri-Corridor (grant 085P1000817). Publisher Copyright: Copyright © 2017 American Society for Microbiology. All Rights Reserved.
N2 - Within the past few decades, the incidence and complexity of human fungal infections have increased, and therefore, the need for safer and more efficient, broad-spectrum antifungal agents is high. In the study described here, we characterized the new tetrazole-based drug candidate VT-1598 as an inhibitor of sterol 14α-demethylase (CYP51B) from the filamentous fungus Aspergillus fumigatus. VT-1598 displayed a high affinity of binding to the enzyme in solution (dissociation constant, 13 ± 1 nM) and in the reconstituted enzymatic reaction was revealed to have an inhibitory potency stronger than the potencies of all other simultaneously tested antifungal drugs, including fluconazole, voriconazole, ketoconazole, and posaconazole. The X-ray structure of the VT-1598/A. fumigatus CYP51 complex was determined and depicts the distinctive binding mode of the inhibitor in the enzyme active site, suggesting the molecular basis of the improved drug potency and broad-spectrum antifungal activity. These data show the formation of an optimized hydrogen bond between the phenoxymethyl oxygen of VT-1598 and the imidazole ring nitrogen of His374, the CYP51 residue that is highly conserved across fungal pathogens and fungus specific. Comparative structural analysis of A. fumigatus CYP51/voriconazole and Candida albicans CYP51/VT-1161 complexes supports the role of H bonding in fungal CYP51/inhibitor complexes and emphasizes the importance of an optimal distance between this interaction and the inhibitor-heme iron interaction. Cellular experiments using two A. fumigatus strains (strains 32820 and 1022) displayed a direct correlation between the effects of the drugs on CYP51B activity and fungal growth inhibition, indicating the noteworthy anti-A. fumigatus potency of VT-1598 and confirming its promise as a broad-spectrum antifungal agent.
AB - Within the past few decades, the incidence and complexity of human fungal infections have increased, and therefore, the need for safer and more efficient, broad-spectrum antifungal agents is high. In the study described here, we characterized the new tetrazole-based drug candidate VT-1598 as an inhibitor of sterol 14α-demethylase (CYP51B) from the filamentous fungus Aspergillus fumigatus. VT-1598 displayed a high affinity of binding to the enzyme in solution (dissociation constant, 13 ± 1 nM) and in the reconstituted enzymatic reaction was revealed to have an inhibitory potency stronger than the potencies of all other simultaneously tested antifungal drugs, including fluconazole, voriconazole, ketoconazole, and posaconazole. The X-ray structure of the VT-1598/A. fumigatus CYP51 complex was determined and depicts the distinctive binding mode of the inhibitor in the enzyme active site, suggesting the molecular basis of the improved drug potency and broad-spectrum antifungal activity. These data show the formation of an optimized hydrogen bond between the phenoxymethyl oxygen of VT-1598 and the imidazole ring nitrogen of His374, the CYP51 residue that is highly conserved across fungal pathogens and fungus specific. Comparative structural analysis of A. fumigatus CYP51/voriconazole and Candida albicans CYP51/VT-1161 complexes supports the role of H bonding in fungal CYP51/inhibitor complexes and emphasizes the importance of an optimal distance between this interaction and the inhibitor-heme iron interaction. Cellular experiments using two A. fumigatus strains (strains 32820 and 1022) displayed a direct correlation between the effects of the drugs on CYP51B activity and fungal growth inhibition, indicating the noteworthy anti-A. fumigatus potency of VT-1598 and confirming its promise as a broad-spectrum antifungal agent.
KW - Aspergillus fumigatus
KW - Fungal infections
KW - Inhibition
KW - Sterol 14α-demethylase (CYP51)
KW - VT-1598
KW - X-ray structure
U2 - 10.1128/AAC.00570-17
DO - 10.1128/AAC.00570-17
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
M1 - e00570-17
Hargrove TY, Garvey EP, Hoekstra WJ, Yates CM, Wawrzak Z, Rachakonda G et al. Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum Antifungal Activity. Antimicrobial agents and chemotherapy. 2017 Jul;61(7):e00570-17. doi: 10.1128/AAC.00570-17


Under the direct supervision of the Registrar, Records Specialist will provide a high level of quality customer service to assist students with enrollment. Also, maintain student files, process enrollment verifications, loan deferments, assist with institutional, state and federal reports.
Process student enrollments both in person and on the phone.
Maintain high school release forms.
Prepare, mail, and record transcripts.
Process Guided Studies enrollments and completions.
Assist with annual state audit preparation.
Process enrollment verifications and loan deferments.
Assist with the preparation of institutional, state, and federal reports.
Maintain "Wait" and "Closed" class lists.
Act as the Veteran's Administration Representative.
Perform other duties as assigned by the Registrar.
Must be PC proficient, including word processing, Excel, and data base management.
Exceptional office skills, including: keyboarding, filing, calculator, and telephone skills.
General knowledge of other office equipment.
Must possess a strong work ethic and commitment to working as an effective team member in a high traffic office.
Must be able to work well with students, the public, faculty, peers, and administrators.
Experience in student records, academic advising, and other student services.


text:
iPONT's Showcases 3DTV without glasses as part of BBC's Wimbledon 3D Experiment
Discussion in 'News' started by macavity, Jul 8, 2011.
macavity New Member
Oxford - 29 June, 2011: iPONT International is showcasing its 3D TV without glasses technology at BBC Television Centre as part of the BBC's 3D broadcast experiment during the Wimbledon Championship men's final.
On Sunday 3 July, screen supplier 3D Exposure, powered by iPONT's glasses free 3D technology come together to supply 42" and 65" auto-stereoscopic (glasses-free) screens as part of the BBC's first free-to-air 3D trial. Presented alongside other 3D TV technologies, iPONT & 3D Exposure will give visitors an opportunity to see what 3D without glasses looks like.
Matthew Young, director, iPONT UK; "The men's final is such a focal event in the UK sporting and cultural calendar, so we're thrilled to be part of it. While everyone loves the added depth and perspective that 3D brings, nobody likes wearing darkened-spectacles when watching sports as it detracts from the enjoyment. iPONT and 3D Exposure have come together to provide the audience with the screen and real time conversion. We're also looking forward to their feedback as it will be immensely valuable for our ongoing product development."
iPONT International will demonstrate its technology to the ticketed crowd on a wide-angle auto-stereoscopic (glasses-free) 3D LCD display with an iPONT 3D TV Box, a proprietary set-top box that streams real-time 3D broadcast content from BBC 3D trial.
The 3D auto-stereoscopic LCD displays, available in screen sizes from 27" to 65" (and even in portrait format), provide detail from a colour palette with no image 'ghosting'. The displays can be viewed in daytime conditions and feature a wide viewing cone of 120° mirroring the same conditions a TV set is used in the home. iPONT's 3D TV box technology, available as a set-top box, converts any stereo 3D broadcast/streamed signal into real-time auto-stereoscopic one for use on glasses-free 3D TVs and displays. The 3D TV box can handle Internet, satellite, cable and terrestrial services that stream 3D content directly into the home or business.
The event is part of a wider public experimental 3D screening of the men's singles final which is also taking place in a select number of UK cinemas around the country. License payers were able to apply for free tickets via a random draw which took place between Wednesday 8th and Monday 13th June.
For more information, visit http://www.ipont.co.uk/ / http://www.bbc.co.uk/
macavity, Jul 8, 2011
best 3D TV or screens without using glasses from experience.
passive glasses 3dtv filter technologies
Cheap 3d tv without glasses?
BBC 3d on an LG Cinema monitor
3D TV without glasses
Wimbledon in 2012 in 3D
Microscope Experiment
Without creating new themes will update this


strong enough to be vibrated direct in to wet concrete.
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Today's message was delivered lighthearted. You know, just something to think about….not beat yourself up over…no judgment.
We are comfortable with comfortable. We are comfortable with same-o same-o. Many of us a have a comfort zone and we like to stay in it.


text:
Connecticut is no Alabama — and says so
by Paul Stern
As if it were possible, relations between President Donald Trump and Democrats worsened last week when Trump angrily announced he would no longer work with them on infrastructure improvements or other projects until they drop their multiple investigations of his conduct.
Some said it was just Trump's excuse to avoid having to find $2 trillion for the infrastructure project (that Connecticut is not ready for anyway). Others said House Speaker Nancy Pelosi had deliberately triggered Trump's wrath when she repeated the often-heard comment that the president had been attempting a "cover-up" through his refusal to comply with Congressional subpoenas and other demands.
Elsewhere in Washington, Connecticut lawmakers like Sen. Richard Blumenthal were reacting to recent passage of Alabama's stringent anti-abortion legislation some see as a warm-up to a challenge to Roe v. Wade. Blumenthal was among those introducing the Women's Health Protection Act to guarantee access to legal and safe abortions.
U.S. Sen. Richard Blumenthal outside the Capitol introducing the Women's Health Protection Act.
Blumenthal was also on hand when U.S. Rep. Rosa DeLauro, D-3rd District, joined others in the Connecticut delegation to introduce a federal version of "Ethan's Law," a measure to ensure safe storage of firearms. It is similar to a measure passed in the Connecticut state Senate on Thursday as the parents of Ethan Song, — a 15-year-old accidentally killed with a neighbor's pistol – watched in gratitude.
Gov. Ned Lamont addressed the Alabama abortion law issue by joining with Lt. Gov. Susan Bysiewicz in an invitation for women-owned businesses in that state (and others with harsh anti-abortion statutes) to relocate here.
He and state Senate Democrats do not see eye-to-eye, however, on a bill creating a paid family and medical leave insurance policy for the state – a measure approved Wednesday night despite Lamont's threat of a veto. The governor has also conceded that his plan to impose highway tolls will not be voted on by the June 5 end of the legislative session, so he expects to take up the matter in a special session after.
mark pazniokas :: ctmirror.org
Michael and Kristin Song, center, react to final passage of Ethan's Law. At right is their daughter, Emily.
The governor is on board with major initiative to create a "public option" health insurance plan partly paid for by effectively reversing – in Connecticut – the elimination of the Affordable Care Act's mandate that all adults have health insurance or pay a penalty.
Lamont has also apparently come to an understanding with lawmakers on a state budget, agreeing on a so-called "mansion tax" but not the income tax increase on the super rich sought by progressive Democrats. He has also agreed to higher reimbursement rates for state nursing homes, a move that seems to have caused nursing home workers to abandon their threat to strike.
For their part, legislators approved raises for state troopers and are moving a bill that would establish a health and human services network to assess the needs of the LGBTQ community. By a margin of 122 to 24, the House approved a bill that will make black and Latino studies part of every high school's curriculum.
The was no such consensus on whether to require schools to teach climate change – a notion that brought out a number of climate change doubters from the ranks of the Republicans.
Paul Stern Paul is the part-time assistant editor and the primary handler of the Mirror's Viewpoints commentaries. He has more than 40 years of reporting and editing experience at newspapers in New Jersey, Florida and Connecticut. He worked 22 years at the Hartford Courant in various editing roles including as deputy state editor, assistant editor of Northeast Magazine, and as an associate editor at Courant.com.
Best of 2019: Key Dems press bill to increase minority recruitment at Coast Guard Academy
The bill is a response to allegations of discrimination and a racially hostile environment at the school.
Navy cuts number of EB Virginia-class subs in new contract
Electric Boat wanted the Navy to include 10 subs, and possibly 11, in the so-called "Block 5" contract. But the Navy agreed to only nine.
Electric Boat facing mounting challenges as sub work ramps up
There continue to be concerns about EB's ability to build the new Columbia-class submarine alongside its smaller Virginia-class attack subs.
Talk of gun violence, little else
In national politics last week there was talk of little else than gun violence, white nationalism and gun control following the fatal shootings of 31 people in Dayton, Ohio and El Paso, Texas. There was little more than talk, too.
Politics and the 'dark psychic force of collectivized hatred'
President Donald Trump insists he is not a racist, but 51 percent of Americans believe he is, according to a Quinnipiac University poll released last week. Certainly his "send her back" comments about Somalia-born U.S. Rep. Ilhan Omar of Minnesota and last week's jabs at U.S. Rep. Elijah Cummings of Baltimore did nothing to dispel that […]


Last week we had the pleasure of planning a surprize birthday picnic for one of our clients. We do love surprizes! But as Durban weather would have it, it yet again sent us running in doors! We were a bit disappointed as the set up we had in mind would have been perfect on lushy green lawns. But alas, we kept our spirits high and put together a special set up for our client. We went the more traditional route with the red and white checkered table cloths and the look came together so nicely!


text:
Q: Making a Portable Executable using FASM in Ubuntu Stack Community !
I am currently on Ubuntu 17.10 and an assembly language learner. When I was on Windows, I used a library named 'win32a.inc' and "MyLib.inc" to read_eax and print_hex. The Syntax used to be like this:
format PE console
include 'win32a.inc'
entry start
section '.text' code readable executable
start:
     mov eax,0xffff
     call print_eax
push 0
call [ExitProcess]

include 'MyLib.inc'

But not having a good experience on Windows, made me switch to Linux. I did this to install fasm:
sudo apt-get install fasm

But when I try to make an executable (I plan to run it with wine) I get an error on terminal: 'win32a.inc' source file Missing.
'win32a.inc' is a default fasm library on Windows. I don't know how I could use it in Linux. I have the backup of all the Windows Libraries though ;_;

Is there a way I can make a portable executable in Linux using FASM ??

A: You can compile to any type of files supported by FASM on any OS.
The trick is that Windows port of FASM treat the filenames as case insensitive, but Linux FASM treat them as case sensitive.
So, check the case of the file names used in the include directives.
The real filenames of the FASM default include libraries are all UPPERCASE. So, you need to use WIN32A.INC if you want to compile this code with the Linux (or any other Unix type OS) FASM.


For the June 8 2017 event. Nominations accepted at the April and May Roundtable events.
This generic Troop Handbook is intended to be used as a starter and modified by the Troop. This handbook was a Doctor of Commissioner Science thesis for Commissioner Walter Beauchamp (former Scoutmaster), and was reviewed and approved by Bruce Anderson, Council Commissioner.


text:
Like my site?
Slightly less broke than the average law student?
I accept donations!
You can fuel a poor law student's Taco Bell addiction!
(Don't feel bad if you don't) (Not tax-deductible)
Property I, Pages 193–198
Stump v. Whibco
Back to List of Briefs
Back to Property I Briefs
Superior Court of New Jersey, Appellate Division, 1998
View opinion on Lexis Advance
View opinion on WestLaw
View opinion on Google Scholar
View opinion on Leagle
Plaintiffs bought land from the Coxes in 1974. The Coxes bought this land in 1948 and replaced the fence at some point without surveying. The plaintiffs improved this land and thought that it was their own until 1990, when it was discovered that part of it was actually owned by defendant.
Procedural History:
The trial court concluded that the plaintiffs had failed to satisfy New Jersey's 30-year limitations period.
Did the fence satisfy "open and notorious" possession?
The possession must be open and notorious, so that it could be noticed by the true owner.
Reasoning:
The fence was small and close to the actual border. It could not be noticed that it was wrong without a survey, so the true owner was not expected to notice it.
Holding:
No, it was not open and notorious possession. Affirmed.
Made by Matthew Miner


Meet the legends of 19th-century Parisian nightlife in The Chrysler Museum of Art's spring keynote exhibition, The Paris of Toulouse-Lautrec: Prints and Posters from The Museum of Modern Art. The exhibition is on view from March 10 to June 18, 2017. Admission is free.
Henri de Toulouse-Lautrec is synonymous with the Belle Époque, or Beautiful Era, in Paris. He created iconic works of the hedonistic nightlife that still define the ideal of bohemian urban life today. His brief 10-year career, from 1891 until his death in 1901, was a manic celebration of the freedom Paris offered and his work gave enduring renown to many of its star performers. The electric color, bold shapes and restless energy of his designs beckoned workers, aristocrats and foreign tourists into the new café-concerts, cabarets and other haunts of Montmartre.
The exhibition is organized thematically around the main facets of Toulouse-Lautrec's life in Paris: the new café-concert culture, entertainment on stage and the daily life of the women performers onstage and off. He was commissioned to produce promotional posters of groundbreaking performers like dancers Jane Avril and La Goulue (stage name of Louise Weber), along with audacious impresarios like Aristide Bruant. In addition, he depicted everyday denizens of the city, including the private lives of prostitutes captured in his lithographic portfolio, Elles (1896). The portfolio of 12 prints shows the women not at work, but in scenes of daily life — sipping coffee in the morning or washing before a mirror.
Toulouse-Lautrec mastered the relatively new art of lithography, an intricate printmaking process based on the principle that grease and water are repellent. Like many Parisian artists, his printmaking style was heavily influenced by Japanese woodcut prints being exported to Europe for the first time.
The Japanese influence on Toulouse-Lautrec will be explored in Inspiring Impressionism, a complementary exhibition of Japanese Ukiyo-e woodcut prints from the Chrysler Museum collection. Named Ukiyo-e or "floating world pictures" after the pleasure district of Tokyo, they first showed celebrity actors and courtesans, and later branched into landscapes and historical subjects. The prints became wildly popular in Paris after Commodore Matthew Perry's 1853 voyage to open Japan to foreign trade — a mission that began in Hampton Roads, forever changing the worlds of commerce and art. Japanese artist Hibata Ōsuke documented this visit, and the Chrysler owns a rare copy of his images of Perry and his squadron, showing probably the first foreigners seen in Edo in more than 200 years. The Museum will also exhibit famed prints from Utagawa Hiroshige's remarkable series, 53 Stations of the Tōkaidō Road.
Toulouse-Lautrec was just 36 when he succumbed to a stroke in 1901, leaving behind 368 prints and posters pushing the boundaries of design. Explore his genius in The Paris of Toulouse-Lautrec, at the Chrysler Museum from March 10–June 18, 2017.
The Paris of Toulouse-Lautrec: Prints and Posters from The Museum of Modern Art was organized by Sarah Suzuki, Curator, Department of Drawings and Prints, The Museum of Modern Art, New York.


text:
Astronomy,
Atom & Cosmos,
Planck by Planck
The upcoming ESA mission will study the cosmic microwave background radiation for clues about the dawn of time
Ron Cowen
1:56pm, March 27, 2009
Editor's note: This story was originally posted April 11. The mission successfully launched May 14.
Pssst! Want to see the birth of the universe?
Astronomers say it's not a scam. The launch of the European Space Agency's Planck mission, set for May 6, will put into orbit a new tool —the microwave equivalent of polarized sunglasses — that may offer a view of the dawn of time.
Before the first galaxies, before the first stars, there was light —the brilliant glow of radiation created during the Big Bang, 13.7 billion years ago. The remnant of that ancient light, now cooled by the expansion of the universe to a frigid 2.7 kelvins, is known as the cosmic microwave background. Instruments on the Planck craft will explore this radiation in exquisite and unprecedented detail.
To minimize


The new moon on 18 April 2015 falls in Aries decan 3 at 28 degrees Aries. Harsh aspects involving Venus means that intimate relationships may suffer through misconceptions, delays or separations. Positive aspects to Mercury and Mars suggest that more success will be had by concentrating on new goals or turning over a new leaf.
A new moon represents the end of one cycle and the beginning of a new 28 day cycle. All possibilities are on the table and you can rightly put yourself in the forefront of new plans for the future. Old habits, behaviors and beliefs can be questioned as you search for new and inventive ways to make progress. This is the ideal time to make a fresh start and start writing down a to-do list on a blank sheet of paper.
However, the impulsive and enthusiastic nature of a new moon means that not all new projects will succeed. The best time for making a fresh start and for beginning new projects is during the first two weeks of a new moon cycle. The waning moon phases in this case lasts from the April 18 new moon until the May 3 full moon.
This new moon on 18 April 2015 falls at 28 degrees Aries (28♈25). There are no major aspects to this degree but there is a fixed star influence. There are also a number of other aspects with tight orbs which color this new moon. Firstly, the fixed star Al Pherg at 27♈01 imparts a positive influence on the new moon. This star in the tail of the Northern Fish in constellation Pisces gives "preparedness, steadiness, determination and final success". This means that the new projects started after this new moon should have a good chance of success.
Al Pherg also has a more mystical influence. It can offer occult knowledge about ourselves and where we come from. However, if this degree is not well aspected in your chart, this knowledge can be too overwhelming and lead to mental instability. In general, other aspects in the new moon horoscope will reveal how this plays out.
Mercury sextile Neptune stirs the imagination to great heights. Perception is well above average and intuition should be strong and accurate. This mental sensitivity applies just as much to ordinary conversations as it does to psychic awareness. This will play out well in regards to the occult knowledge suggested by the fixed star Al Pherg. It will also help in the planning of new projects, making it easier to write down your to-do list.
Venus square Neptune will affect your intimate relationships mostly, but not in a good way. There will be a tendency to over idealize your partner or prospective partners. If dating, then high moral standards must be maintained in order to avoid scandal or disappointment. Venus square Neptune can also make you lazy, but I doubt this will be the case given the enthusiasm brought about by a new moon, plus the following Mars aspects.
Mars square Jupiter will aggravate any relationships difficulties brought about by Venus square Neptune. Lack of tact and a tendency to exaggerate and take risks could lead to embarrassing situations. As for turning over a new leaf or starting new projects, Mars square Jupiter should have a less adverse effect. There may still be a tendency to take rash actions or over-estimate your capabilities, but Mars trine Pluto should provide the inner strength to stay on course. The fixed star Al Pherg also provides the preparedness and steadiness to compensate for the rashness of this aspect.
Mars trine Pluto will have a similar influence to that of the star Al Pherg. It is an aspect of determination and success. It will come in most useful if you use this new moon to eliminate old habits because of it regenerative nature. Desires and ambitions are heightened with Mars trine Pluto. You strong desires have a good chance of being fulfilled because of increased stamina and perseverance.
Mars trine Pluto is also a very sexual aspect and will overpower to some extent any confusion in relationships caused by Venus square Neptune. However, this is not a good moon phase for love relationships, which is confirmed by Venus opposite Saturn. More success is on offer by drawing on your imagination and intuition to eliminate bad habits, turn over a new leaf or start new projects. You should have the energy and determination to see them through to completion.
Spot on Jamie, thanks! Having the benefit of knowing what's going on astrologically helps us get through many tricky icky situations!
broke up with my bf of 3 years today.
the first uranus square natal uranus of my life started this week.


text:
Jesper Kristensen est un footballeur danois, né le  à Esbjerg.

Biographie

En tant que milieu de terrain, il fut international danois à 4 reprises (1994-1995) pour aucun but marqué.

Il participa à la Coupe des confédérations 1995. Il fut titulaire dans tous les matchs (Mexique, Arabie saoudite et Argentine), se prenant un carton jaune en finale et remporte le tournoi.

Il joua dans deux clubs : Esbjerg fB et Brøndby IF. Il remporta un championnat danois, une coupe du Danemark et deux supercoupes du Danemark. Durant la saison 1995-1996, il joue les premiers matchs de la saison, mais il se blesse et met prématurément un terme à sa carrière.

Clubs
 19..-1991 : Esbjerg fB
 1991-1996 : Brøndby IF

Palmarès
 Coupe du Danemark de football

 Vainqueur en 1994
 Finaliste en 1996
 Championnat du Danemark de football
 Champion en 1996
 Vice-champion en 1995
 Supercoupe du Danemark
 Vainqueur en 1994 et en 1996
 Coupe des confédérations
 Vainqueur en 1995

Liens externes

Naissance en octobre 1971
Footballeur international danois
Joueur de l'Esbjerg fB
Joueur du Brøndby IF
Naissance à Esbjerg

redpajama_set_name: RedPajamaWikipedia