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DNA Sonification For Public Engagement in Bioinformatics
Heleen Plaisier, Thomas Robert Meagher, Daniel Barker
published 14 Jul, 2021
Read the published version in BMC Research Notes →
Objective: Visualisation methods, primarily color-coded representation of sequence data, have been a predominant means of representation of DNA data. Algorithmic conversion of DNA sequence data to sound – sonification – represents an alternative means of representation that uses a different range of human sensory perception. We propose that sonification has value for public engagement with DNA sequence information because it has potential to be entertaining as well as informative. We conduct preliminary work to explore the potential of DNA sequence sonification in public engagement with bioinformatics. We apply a simple sonification technique for DNA, in which each DNA base is represented by a specific note. Additionally, a beat may be added to indicate codon boundaries or for musical effect. We report a brief analysis from public engagement events we conducted that featured this method of sonification.
Results: We report on use of DNA sequence sonification at two public events. Sonification has potential in public engagement with bioinformatics, both as a means of data representation and as a means to attract audience to a drop-in stand. We also discuss further directions for research on integration of sonification into bioinformatics public engagement and education.
Health Economics & Outcomes Research
sonification
As the field of genomics has matured, the need to provide novel tools for representing DNA sequence data has become pressing. This need ranges from comparative investigation of sequence variation across multiple sequences, searches for functional domains across extended sequences, searches for sequences of varying length within and between organisms that share homology or are otherwise similar, and capturing and comparing entire genomes. As genomics data and its potential for scientific investigation has grown, so too have methods for representing data. Visual sequence data has been a standard approach, but it has its limitations, especially when long sequences are involved. Algorithmic conversion of DNA sequences to sound – sonification – offers an alternative means of representing DNA sequences that in turn draw upon other human sensory mechanisms.
DNA sequence visualisation has a relatively long history in bioinformatics. Even the representation of the four bases as letters in the alphabet – A, C, G and T, with the sequence of one strand of the double helix represented as a string of such letters – is a simple visualisation, with a long tradition in databases and publications involving DNA sequence (e.g. [1, 2]). Visualisation of genome annotation, pairwise sequence alignment diagrams and multiple alignments take visualisation further, by adding visualisation of properties of the sequence (e.g. predicted gene structures or similarity to other sequences).
However, like any representation, visualisation has limits. In a research context, visualisation of large amounts of sequence is constrained by the size of a computer screen, the ability to convey diverse information through colours or symbols, and the attention of the researcher. In the context of public engagement with science, DNA sequence has a monotonous visual appearance, at odds with the "whizz-bang" often expected in such public displays or shows.
Although the quantity and apparently random nature of large DNA sequences is engaging for a short time, more detailed examination of DNA sequence or annotation demands a level of focus that is atypically high for a public drop-in event or short activity. At public events we have had success with a wide range of ages using the Phylo game [3], where anyone can attempt to improve multiple alignments of regions of genes associated with human disease [4]. However, any one game or activity can only present a small aspect of bioinformatics. Although we have had success introducing bioinformatics to school pupils [5, 6] and introducing bioinformatics and computational science to the public in a science centre [4], bioinformatics as a whole is rather lacking in public engagement activities.
We aim to help fill this gap by means of sonification of DNA, where the representation of sequence is auditory rather than visual. Since music is widely understood and used for relaxation and entertainment, this may be more attractive to a public audience than a screen full of DNA sequence or associated data. By use of the Sonic Pi program [7] for sonification, we make the underlying program visible and customisable in real-time. This also provides a link between DNA and programming, which in is central to bioinformatics in general.
Sonification of scientific data in is not new (e.g. [8]). More specifically, the use of DNA sequence to generate music has a history in music composition for artistic purposes, and there is a developing literature on DNA sonification for research [9]. However, though DNA sonification examples for public engagement exist (e.g. [10]), they appear rare. Based on our preliminary activities, DNA sonification has potential for successful public engagement activities. Further efforts in this area are warranted. We report a brief analysis from public engagement events we have conducted that featured sonification. We also discuss some further directions for research on integration of sonification into public engagement.
At Picademy in Glasgow on 29 November 2016, an initial sonification project was carried out. The coding sequence of GULO from mouse was converted to a Sonic Pi program, using search-and-replace to convert bases A, C, G and T to notes A, C, G and Midi 20 respectively. A filtered bass drum was added at the start of each codon (i.e. every three bases). Subsequent events used Raspberry Pi computers running the 4273π variant of GNU/Linux [11].
Subsequently we incorporated sonification into a series of public events as follows.
In preparation for Doors Open Day, a public drop-in event at the Ashworth Laboratories, King's Buildings, University of Edinburgh on 23 September 2017 from 10 AM to 4 PM [12], further sonifications were prepared, using a Perl script we wrote to convert DNA sequence in Fasta format to a Sonic Pi program followed by manual editing of the result. The event brought in a range of different people, some potential new students and parents who were interested in biology, but also families with young children and other local people. For this event, the sonification of "T" was changed, from the rather low Midi 20 to "E". These additional sonifications consisted of: (1) a codon-free version of GULO; (2) a rave version of the GULO sonification, in which the 1:3 beat was switched with a 4:4 beat for musical effect; and (3) a sonification of part of an intron of the CFTR gene in human, which includes a dinucleotide microsatellite (AT), to highlight the potential research benefit of sonification. Additionally, a brief tutorial to Sonic Pi including DNA sonification exercises was written and printed out in laminated form, along with the GULO coding sequence and the start of the intron sequence from CFTR, with the microsatellites highlighted. Doors Open Day 2017 at the Ashworth Laboratories was attended by at least 258 people. During the event, we engaged ~30 visitors in a discussion about DNA, mainly by approaching them with the question "Have you ever wondered what DNA would sound like?". The event was evaluated by means of direct experience and diaries of H.P. and D.B.
As part of Ada Lovelace Day, a free but ticketed public event at the James Clerk Maxwell Building, King's Buildings, University of Edinburgh on 10 October 2017 [13], we gave an introductory presentation for ~50 participants, and offered three workshops later in the day, which were attended by a total of 13 people. The workshops lasted approximately 30-40 minutes each and consisted of a short DNA investigation using BLAST [14] with the GULO gene (as in [15]), followed by a guided exploration of prepared DNA sonifications, and the opportunity to go through the printed sonification tutorial. The event was evaluated by means of a short questionnaire and diaries of H.P. and D.B.
Our preliminary study indicates that DNA sonification is highly suitable for public engagement activities, both for short drop-in events and for more focused workshops.
Doors Open Day was a large public event, during which people engaged well with the sonification activity. The question "Have you ever wondered what DNA would sound like" was a successful way of starting a discussion about DNA. Everyone who was asked this question stayed to listen to a sample of our sonifications and engaged in a short discussion about DNA. Visitors were guided through prepared sonifications, and given the opportunity to go through the printed sonification tutorial. Visitors found the event creative and inspiring and were either happy to see it as a light distraction, or to discuss scientific applications. Relatively little use was made of the Sonic Pi tutorial. During the event, Minecraft proved a distraction, so we discretely removed it from the main menu of each Raspberry Pi. Later, Scratch was also some distraction. For the future, we would remove these in advance because they are not part of our display. URL-based restrictions on Web browser access may also have some value. The Phylo game ran slowly at times on the Raspberry Pi computers (a problem that would be reduced or removed with newer models of the hardware).
The sonification workshops during Ada Lovelace Day were well-attended, and the audience appeared engaged. Six participants completed questionnaires. Others did not, due to leaving early for lunch (1 participant) and leaving at short notice to collect their bags from the main activity room (5 participants). When asked what the best thing about the workshop was, participants stated "The opportunity to engage with DNA or Biology from a different perspective. Hearing a sequence made me think of it as an object in a different way."; "Sonic Pi (amazing!)"; and "Updating me on sequence investigation". When asked what the worst thing about the workshop was, participants did not have many comments, i.e. "None", "Nothing", "not enough time!". We had difficulty connecting to the University WiFi network and used a 4G phone as a WiFi hotspot instead. However, this was resolved before participants arrived and was not noticeable to them. The event was a success. However, H.P. and D.B. thought a little more time to focus on sonification would be helpful for such events in the future.
It appears that DNA sonification engages both researchers and the public in thinking about DNA from a different perspective. Further development of DNA sonification for public engagement activities is warranted.
Although our preliminary study is sufficient to suggest DNA sonification has potential in public engagement activities, a larger study would be required to discover the full limits of its successful application, for example in terms of audience age, gender, ethnicity, academic background and in terms of event type. Our audience for evaluation consisted of adults, mostly staff and students at Edinburgh University. We recommend a larger program of qualitative and quantitative analysis, with a diverse range of audiences including young people.
In addition, our sonification has been relatively simple. Future directions involve codon or protein sonification. However, for public engagement, it will be important to avoid strong reliance on biological knowledge which the audience may lack. For example, multiple alignment sonification may be particularly valuable for research (Martin et al, in prep.). But multiple alignment depends on other biological concepts such as homology and cross-sequence comparison, unlikely to be rapidly comprehensible to the general public. The Phylo multiple alignment game [3] is a counter-example. However, as well as an exercise in multiple alignment, Phylo may be understood as a logic puzzle – with the benefit of a link to real data and disease – potentially bypassing these biological concepts for many users while leaving them as useful discussion points for those with expertise in the area.
One promising future direction for public engagement and education may be to highlight the effect of frameshift mutations. We have developed and apply a workshop for biology students in secondary education [15] (open educational resources available at [16]), centred on the GULO gene (e.g. [17]), which in humans is disrupted by frameshift mutations. Visually, a frameshift mutation is difficult to notice on-screen in BLASTN results comparing the GULO coding sequence and the human pseudogene. A frameshift is indicated by a single "-" among DNA symbols.
In conclusion, sonification has a demonstrated potential for public outreach and engagement. Our preliminary efforts to use this methodology were well-received. It is our aspiration to build on these preliminary efforts to use sonification to make DNA sequence information entertaining as well as informative and to increase the nuance and complexity that we convey in public engagement.
Sound files, a Perl script and Sonic Pi scripts supporting the conclusions of this article are available in the University of Edinburgh's DataShare repository, https://hdl.handle.net/10283/3868.
This work was funded by the Science and Technology Facilities Council (STFC) grant numbers ST/R000328/1 and ST/T000872/1. The funding body had no role in the design of the study or collection, analysis, or interpretation of data or in writing the manuscript.
H.P. and D.B. designed and carried out the research and analysed the data. All authors wrote the manuscript. All authors read and approved the final manuscript.
We thank Craig Steele for work on the project at the Glasgow PiCademy event. We thank Edward Martin for comments on an earlier version of this manuscript.
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Kawrykow A, Roumanis G, Kam A, Kwak D, Leung C, Wu C, Zarour E, Phylo players, Sarmenta L, Blanchette M, Waldispühl J. Phylo: a citizen science approach for improving multiple sequence alignment. PLoS One. 2012;7:e31362.
McDonagh JL, Barker D, Alderson RG. Bringing computational science to the public. SpringerPlus. 2016;5:259.
Barker D, Alderson RG, McDonagh JL, Plaisier H, Comrie MM, Duncan L, Muirhead GTP, Sweeney SD. University-level practical activities in bioinformatics benefit voluntary groups of pupils in the last 2 years of school. International Journal of STEM Education. 2015;2:17.
Bain SA, Meagher TR, Barker D. Design, delivery and evaluation of a bioinformatics education workshop for 13-16-year-olds. Journal of Biological Education. 2020;doi:10.1080/00219266.2020.1858932
Aaron S. Sonic Pi – performance in education, technology and art. International Journal of Performance Arts and Digital Media. 2016;12:171-178.
Barrett N, Mair K. Aftershock: a science-art collaboration through sonification. Organised Sound. 2014;19:4-16.
Temple MD. An auditory display tool for DNA sequence analysis. BMC Bioinformatics. 2017;18:221.
Temple MD. Real-time audio and visual display of the Coronavirus genome. BMC Bioinformatics. 2020;21:431.
Barker D, Ferrier DEK, Holland PWH, Mitchell JBO, Plaisier H, Ritchie MG, Smart SD. 4273π: bioinformatics education on low cost ARM hardware. BMC Bioinformatics. 2013;14:243.
Doors Open Day 2017, The University of Edinburgh College of Science and Engineering. https://www.ed.ac.uk/science-engineering/news-events/archive/2017/doors-open-day-2017 . Accessed 31 March 2021.
Frantzana A. Ada Lovelace Day 2017 – Celebrating women in STEM. http://eusci.org.uk/2017/10/26/ada-lovelace-day-2017-celebrating-women-in-stem. Accessed 31 March 2021.
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Organon F, 2012, vol. 19, No 3, pp. 306-324.
The paper deals with the semantics of the word only. Though inspired by Lepore's analysis, it offers a different explication of the existential import of concatenations only + singular expression. It is assumed that the meaning of only in the kinds of collocations under scrutiny (i.e., when preceding a singular expression, a general name, a verb or the connective …if…) is context independent in that it can be explicated by a single scheme No other than ξs are ψs. The scheme varies with the variable type to which only is applied purely as a certain kind of operator. The explication of the role of only, when prefixing …if…, offers a new modality based explanation without invoking the notions of sufficient and necessary condition. The concatenations only + expression are, typically, equivalent to more prolix only-free collocations; thus, only is a suit	able device for text compression.


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Canary Islands»Tenerife»Costa Adeje»Callao Salvaje, Tenerife - Things To Do & Travel Guide
Callao Salvaje, Tenerife - Things To Do & Travel Guide
TenerifeCosta AdejeThings to do in Costa Adeje
View of the beach in Callao Salvaje
Callao Salvaje is a tourist destination in the municipality of Adeje, in the very south of Tenerife. It is an ideal place to spend a quiet holiday on the island at any time of the year, due to the warm climate throughout the year.
What to do in Callao Salvaje
Playa de Ajabo
Nightlife in Callao Salvaje
Other day trips from Callao Salvaje
Callao Salvaje is not as developed and large as Costa Adeje for example, which is the major tourist resort in the municipality. This means that if you would prefer a quiet and relaxing holiday in the south of the island, Callao Salvaje would be a good place to stay, as here you will mostly find private apartments to rent, instead of the big all-inclusive hotels, which are usually set up in the larger resorts like Playa de Las Americas, Costa Adeje or Los Cristianos.
Callao is a spot for relaxation and a great base if you want to rent a car and explore the island of Tenerife on your own.
Even by using public transport, you can hop on a bus (known as Guagua in Tenerife) and you can visit the surrounding towns and resorts like Playa Paraiso, Playa San Juan, or Costa Adeje. This way you can alternate which beach you go to every day, without having to travel too far out.
If you decide to rent a car, a great day trip would be to the beach in El Puertito, which is the most charming place in this area of the coast, still undeveloped, but highly popular among locals and surfers. There's even a bar next to the beach where you can have a drink and even lunch, although a bit overpriced for what they serve.
There is a lovely spot above the beach where you could sit under a tree in natural shade to relax or read a book
This is the local beach in Callao Salvaje, with black sand and pebbles, which has only become safe for swimming in recent years after extensive works were carried out in the area. We remember that back in 2012 they were just starting works on this beach.
There used to be a beach bar on Playa Ajabo, but during our last visits in the town in 2018 and 2019, it was closed and there was no nearby place to grab a drink or something to eat. This is quite a shame since the view from the bar overlooking the beach was really lovely.
There are sunbeds and umbrellas on the beach in Callao Salvaje, but this subject sparks a lot of conflicts and controversies in town. This is because the sunbeds and umbrellas belong to the company which used to manage the beach bar (which is now closed), but some individuals, who could be former employees of the bar's owner, still charge a fee for the use of these facilities. There have been several disputes between locals and even tourists who refused to pay the fee set up by these individuals and despite the several complaints to the local authorities, it's not really certain if they have the right to still charge for the use of the sunbeds or not (since the beach bar is not operational anymore).
For us, this is off-putting and it makes us not want to come back to Playa Ajabo or Callao Salvaje, since we want to relax and have a good time while on holiday, not get into fights over such things. We are happy to pay a fee for the use of sunbeds, umbrellas, or toilets like we do on every other beach in Tenerife, but only if this fee is charged legally by the people who are taking care of the facilities and the beach.
We really do hope that this situation gets resolved quickly so that visitors can enjoy a relaxing holiday in Callao Salvaje. If you have more details about changes to the situation, please let us know via our Contact form, so that we can update this article and let people know.
There are no clubs in Callao Salvaje, so there are no noisy establishments to keep you up at night.
Besides the other nearby towns which we previously recommended, you could also go on day trips to:
Playa Abama
Barranco del Infierno - a great day of hiking in the south of Tenerife
These are only the closest places that you could easily visit if staying in Callao Salvaje, but of course you could also go further to visit Teide National Park, Masca village, Los Gigantes and all the other beautiful places to see in Tenerife.
Best Apartments in Tenerife: Kn Aparthotel Columbus (Playa de Las Americas) • Aparthotel Los Dragos del Sur (Puerto Santiago)
Popular hotels in Tenerife: H10 Costa Adeje Palace 4* (Costa Adeje) • Iberostar Bouganville Playa 4* (Playa de Las Americas) • Barceló Santiago (Puerto Santiago)
Luxury 5* hotels in Tenerife: Adrián Hoteles Roca Nivaria (Adeje) • Vincci Selección La Plantación del Sur (Adeje)
See our dedicated guide for the best places to stay in Tenerife.
Best Excursions & Tours: Whale & Dolphin Watching with Drinks & Snacks • Loro Parque Entry Ticket and Shows
16 Best Things To Do in Costa Adeje 2023 - Top Attractions
8 Best Things To Do in Playa de las Americas - Tenerife
11 Best Things To Do in Los Cristianos, Tenerife
Playa Paraiso, Tenerife - Things to do & Where to stay
Best things to do in Playa San Juan, Tenerife (2022 Guide)
10 Best Beaches in Tenerife - White sand beaches & Black volcanic sand
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Canary Islands closed 2022 with 12.6 million visitors, 5.6% less than in 2019
CANARY ISLANDS NEWS
Spain lifts all entry requirements for non-EU visitors
Do you need a minimum of 100 Euros per day to travel to Spain? What is the legal requirement?
Does the six drinks rule apply to Tenerife or the Canary Islands in general?
CANARY ISLANDS DESTINATIONS
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redpajama_set_name: RedPajamaCommonCrawl


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Our Lady of Sheshan, China
Our Lady of China (Simplified Chinese: 中华圣母, Traditional Chinese: 中華聖母, pinyin: Zhōnghuá Shèngmǔ) is the name given to an apparition of the Blessed Virgin Mary in Donglu, China, first appearing in 1900.
An officially-sanctioned image of Our Lady of China was blessed, granted and promulgated by Pope Pius XI in 1928, in response to the requests made by the 1924 Shanghai Synod of Bishops in China, the first national conference of bishops in the country. Following the event, Archbishop Celso Costantini(剛恆毅), Apostolic Delegate in China, along with all the bishops of China, declared the Chinese people dedicated to Our Lady of China, using the official image. In 1941, Pope Pius XII designated the feast day as an official feast of the Catholic liturgical calendar. In 1973, following the Second Vatican Council, the Chinese Bishops conference, upon approval from the Holy See, placed the feast day on the vigil (day preceding) of Mothers Day (the second Sunday of May). Christian devotion to Our Lady of China has been popular in Donglu.
Several churches, chapels, and pastoral centers around the world, predominantly those focused on ministry to Chinese-speaking Catholics, have adopted the name, including a mission in Washington, DC. There is a mosaic of Our Lady of China in the National Shrine of the United States in Washington, DC, established and dedicated in 2002 under the Most Rev. Michael J. Bransfield. There has been some controversy because the image used in the Chapel is not the officially approved image of Our Lady of China, but instead uses the image of Our Lady of China and Baby Jesus painted by John Lu Hung Nien. The late Cardinal Thomas Tien Keng-Hsin, the first Chinese Cardinal, used this image for the prayer card for the persecuted in China, which was widely promoted in the U.S.A. and Canada. Critics have accused John Lu Hung Nien's image of the Virgin Mary, of resembling the Buddhist bodhisattva Guan Yin.
The Our Lady of Sheshan is another, similar apparition which has attained like acclamation and fame among Chinese Christians.
Now in the Philippines, in the Chapel of Our Lady of China now in Binondo Church in the district of Binondo, Manila near in Manila Chinatown with the other devolties from the local Filipinos and the Chinese Filipinos to praying to the church of Our Lady of China here in the Philippines.
The She Shan Basilica (officially: Basilica of Our Lady of SheShan, simplified Chinese: 佘山进教之佑圣母大殿; pinyin: Shéshān jìnjiào zhī yòu shèngmǔ dàdiàn) is a Catholic church in Shanghai, China. The name comes from its location on the western peak of She Shan Hill, located in Songjiang District, to the west of Shanghai's metropolitan area and was at one time the destination of pilgrims from across Asia.
The official name of the church is the Church of the Holy Mother in China. The first church on She Shan hill was built in 1863. During the Taiping Rebellion, Jesuit missionaries bought a plot of land on the southern slopes of the hill. A derelict Buddhist monastery had stood on the site. The remaining buildings were demolished, and a small building was constructed as living quarters for missionaries, and a small chapel. At the peak of the hill (where the Maitreya hall had stood), a small pavilion was built in which was placed a statue of the Madonna.
In June 1870, unrest in Tianjin led to the burning of churches there. The Shanghai Jesuits prayed at the statue of the Madonna and pledged to build a church to her honour in return for her protection. Subsequently, construction of the church began. Wood was shipped in from Shanghai, and stone bought from Fujian. All material had to be ported to the peak by hand. The church was completed two years later. This first church was in the form of a cross, and incorporated features of both Chinese and Western architectural features. A veranda was placed outside the door, with ten columns. Eight stone lions were placed before the church. In 1894, several ancillary buildings were added. These included a chapel half-way down the hill, a shrine to the Sacred Heart, the Virgin Mary, and St. Joseph. Fourteen Stations of the Cross were constructed along the path to the church.
In 1925, the existing church was found to be inadequate, and it lagged far behind other churches in Shanghai in terms of size and ornamentation. The church was demolished and rebuilt. Because the Portuguese priest and architect (叶肇昌) was very stringent about the quality of construction, the whole project took ten years to finish, and the church was completed in 1935.
In 1942, Pope Pius XII ordained the She Shan Cathedral a minor Basilica. In 1946, the Holy See crowned the statue of Our Lady of Zose (Zose being the Shanghainese pronunciation of She Shan) at the apex of the tower.
After the Communist takeover in 1949, She Shan Cathedral was heavily damaged during the Cultural Revolution. The stained glass windows of the church, carvings along the Via Dolorosa, the statue atop the bell tower, and various other works of iconography were destroyed.
In 1874, Pope Pius IX declared that pilgrims who went to She Shan in May (traditionally a Marian month) would receive a Plenary Indulgence. As a result, pilgrims from all over China began to congregate at She Shan in May, a practice that continues to this day.
Every May, the church becomes the destination for pilgrims who travel far and wide to make their annual pilgrimage at She Shan, praying the Way of the Cross, the Rosary and attending Mass at this holy site. Traditionally, many of the Catholics in the area were fishermen, who would make the pilgrimage by boat. This tradition continues among local Catholics, with the result that the creeks around She Shan are often crowded with boats in May.
Currently, She Shan is the only active pilgrimage site for Roman Catholics in China.
After the Cultural Revolution ended, the damage was gradually repaired. The statue was initially replaced with a simple iron cross, and a replacement statue was installed in 2000.
On May 24, 2008 Pope Benedict XVI announced that he had composed a special prayer for Our Lady of Sheshan.
The thirst for God in China is immense and the population is now nauseated by materialism. Mutual love can give birth to abundant fruit for mission.
Labels: Calendar, Christianity, Comparative, Nihilism, Prayer, Religion, Secular Humanism, Secularism
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THE TIGERS IN TRANSITIONERNIE: A VOICE OF STABILITYIN BASEBALL'S SEA OF CHANGE
by Mitch Albom | Nov 21, 2008 | Detroit Free Press | 0 comments
LAKELAND, Fla. — Year after year, winter after winter, the voice stirs from under the snow. It heats up, it melts free, it crosses your lawn and taps the frost from your window. "Time to wake up," it seems to say. "It's spring. I'm back."
You yawn. You smile. It is a voice you trust, an easy pitch, not too shrill, not too deep, a sprinkle of Southern accent — genteel, that's probably a good word, a voice that would sing you a lullaby or tell you bedtime stories. It asks for nothing, this voice. It never scolds. It never whines. It wants only to live inside your transistor radio, to narrate from your car speakers as you drive on a summer night. It is the human lyric of the double play and the single up the middle. It is the call of a rookie with a smoking fastball. It is the game the way the game would sound if only the game could talk. It is the voice of baseball.
It belongs to Ernie Harwell.
"He's the best," people say, as if stating a law of nature. And he is still here, behind the mike in that little booth at Tiger Stadium. Amidst all the turmoil, all the change, all the money and lawyers and lockouts and strikes, Ernie's voice remains as much real baseball as green grass and orange dirt. We're talking transition? He has seen transition. He has outlasted owners and outlasted managers and watched rookies turn to old-timers and old-timers turn to the grave. He was bellowing into that microphone before his new boss was in high school. He sold his first story to The Sporting News the year Sparky Anderson was born. He used to shag fly balls with Jackie Robinson and ride the train with Gil Hodges. He had a fight with Leo Durocher and called Denny McLain's 30th victory. You name it, he's seen it. And he is still here.
That voice. On your worst days, it can make you feel good. On your good days, it can make you feel better. Bag of potato chips, Ernie on the radio. Window rolled down, Ernie on the radio. Suntan oil, Ernie on the radio. A Tigers game without him would be like playing with a purple baseball. In 30 years with the Detroit club, this is how many broadcasts he has missed: two. One in 1968, for his brother's funeral. One last year, to receive a major award. Oh, yeah. There was this night in the mid-'70s, at Tiger Stadium, against the California Angels, when it began to rain. After a while, an announcement came to the broadcast booth: "Game canceled, doubleheader tomorrow." Harwell, as he had been doing for years, relayed the message over the air — never knowing it was a practical joke. Then he packed up and left.
Ten minutes later, on the freeway, he turned on the radio to hear the postgame program. "Wait a minute folks," said Ray Lane, "apparently, the game has not been canceled. They're going to start back up . . .
"Ernie! Ernie! Wherever you are! Come back!"
Harwell got off the next exit, returned to the park, and finished the broadcast.
See? Even when he tries to leave, the game calls him home. Ding how!"
The cook looks at him. He doesn't understand.
"Ding how?" Harwell repeats.
"Oh, meestah. You speak Chinese?"
"Well, ha ha . . . just that word. I learned it when I was over there."
He smiles. The cook smiles. Everybody smiles. We are in a Chinese restaurant, where baseball is hardly a dominant subject, but people still react to Harwell as if he is an honored guest. His voice does it. It sings of hospitality.
He takes a seat next to his wife, Lulu, whom he met almost 50 years ago at a fraternity dance at Emory College. They talked about books. She thought he was "cute." He proposed in a letter. They still hold hands today.
At 72, Harwell seems more frail now. His face shows the lines of experience, his hair is whitish-blond and often tucked under a beret. He wears glasses, he has for years. Now and then he will dig his fists in his pockets and stiffen while he sucks in a deep breath, as if trying to realign his bones. Breathing is important for the voice, he will tell you, and to this day, he takes a morning walk and holds in air for 10 paces and lets it out for 10 more, a trick he was shown by a Russian violinist back in the 1940s, at his first job, WSB in Atlanta, "The Voice of the South." Those were the days when radio stations used orchestras, not compact disc players.
Ernie Harwell does not have a compact disc player. He does not have an answering machine. He has radios. One in the living room, one in the kitchen, one in the office, one in the family room, one in every bedroom, and one little portable that Lulu takes on her nightly walk around the neighborhood, so she can listen to her husband broadcast the games.
He seems as dedicated to radios as he is to his subject, which has always been baseball, as long as we can remember. Oh, he broadcast some football, some golf, some tennis, some bowling. He wrote articles for Esquire, Colliers and The Saturday Evening Post. He covered the Japanese surrender at Wake Island. While in the Marines, as a correspondent, he had this idea for a story about the president's mail — how much he gets, how much he answers. He contacted the White House. They set up an appointment. Eleanor Roosevelt met him in the Green Room. Alone. They talked for 90 minutes. "She was very accommodating," he says. Eleanor Roosevelt?
Still, the ballpark is Harwell's natural stage. It has been since his first major league season in 1948, working for the Brooklyn Dodgers. His first road game was at Braves Field in Boston. They didn't have a booth. So he and his engineer sat in in the rightfield stands with their equipment on their laps. Can you picture that? "The fans were all around us," Harwell recalls. "Looking over our shoulder, looking over our heads. You had to try to block them out."
You need a hell of a focus. But then, that always has been the strength of a Harwell broadcast. Focus. Oh, he can tell you almost anything about baseball history. He just won't. Not unless it's pertinent. He does not chew fat. He does not drop names. He will talk about the rookie left-hander, tell you which way the wind is blowing, set the bases, shift the outfield, call the pitch, bring you right in — and let you float above the action.
Silence. The magic is in the pauses. Dizzy Gillespie, the famous jazz trumpeter, once said: "It took me my whole life to learn what not to play." So, too, does Harwell know when to leave it alone, when to let the crowd noise or the beer man or your own imagination take the mike from his hands. This is radio. This is play-by-play artistry. What separates him from those other pretenders trying to become famous with their mouths is this: Ernie Harwell respects the game.
Sure, there are flashier names in media. Guys like Harry Caray, who scream
"HOLY COW!" every five minutes. Guys like Al Michaels, who give sports a slick, corporate feel. Guys like John Madden, who are hired to go "BOOM!"
Somewhere along the line, something was lost. Except at Tiger Stadium. Except in that little booth. Baseball nuts in Pennsylvania and Virginia and Indiana still sit in their cars, late at night, fiddling with the knobs, until the signal from WJR wafts in across the skies, and they can hear that voice with the touch of Georgia accent. ("Hello evrahbody, welcome to Tigah baseball
. . .") Make us young again, Ernie. Make it fun again, Ernie. Year after year, in the first game of spring, he opens with the same sentence: "For lo, the winter is past, and the song of the turtle is heard across the land . . ."
He's quoting the bible. Song of Solomon.
That's Ernie's idea of flash.
You know, the game hasn't changed all that much," Harwell says now, after returning home from the restaurant and taking a chair in his hotel room. "A lot of people think the players are more money-minded than before. They say,
'This guy is making $3 million so he won't hustle.'
"But it's all relative. I read a book not too long ago that went back to the 1934 season. It reprinted baseball stories from the top sports writers of the day. And one of those guys wrote 'It's no wonder the players of today don't hustle! They're making $3,000 a year and have two-year contracts!' "
Harwell laughs, perhaps for the irony, perhaps because he can still remember 1934. And 1944. And 1954. Those were the days you rode trains with the players, you played cards, you passed the beer. You glorified their heroics, and shut your eyes to their antics. Harwell was with the Brooklyn Dodgers for much of that time. He rode the trains. He shagged fly balls in the outfield, right alongside the players. He was not afraid to call men such as Robinson, Hodges and Campanella his "friends" — a faux pas amongst today's more hard-bitten journalists.
"I guess I've never really gotten comfortable with the whole antagonistic relationship, especially the drugs and alcohol thing," he says. "You know, I've never seen a person use drugs. I never have. In the old days, you might see a player get on the train a little tipsy from too many drinks after the game. But things were a lot different. The feeling was much more paternalistic, between the reporters and the players — and between the owners
and the players. Back then, the owners were former baseball men themselves, or baseball families. If a guy got drunk, the owner would bail him out of jail, give him an advance, never say anything about it.
"Nowadays, they don't do that. They're at odds with each other. And besides, the owners aren't the same kind of people. They're corporations, guys who made a lot of money and want to buy into the game."
Harwell has endured his share of owners. And general managers. He has worked for the Dodgers, the Giants, the Orioles. He has done more than 4,500 Tigers games. He has witnessed the strikes and lockouts and walkouts and players coming from jail and players going to rehab centers.
He is asked whether the participants could ever do something so terrible, so revolting, that the fans would give up on the game?
"I honestly don't think so," he says. "They've gone through just about everything there is. To me, baseball is sort of like the church. The church has always taken all kinds of abuse. People in it have made terrible mistakes in the name of religion. And yet it survives.
"Besides, I really believe if a guy is a jerk, but he gets up there in the bottom of the ninth and hits a three-run homer, the fans are going to cheer, no matter what. That's baseball. It goes on and on."
And so does Harwell. Once upon a time, he dreamed of the cheers himself. As a child in Georgia, he spent hours on the sandlots. Second base. Fielding grounders. Broadcasting was probably the last career anyone would have predicted; after all, young Harwell's tongue did not move properly when he spoke — they call it tongue-tied — and for years, everything came out with an "f." The word sister, he pronounced "fifter." Christmas was "fifmaf." Once a month, in school, he would have to stand up and "debate or declare." The other kids would laugh. "Ernie can't talk right. Ha ha ha . . . "
That he survived that trauma and prospered from it (with the help of an elocution teacher) is credit to his quiet strength. And the fact that he had bigger things to worry about. When Ernie was 6, his father, Gray, who owned a furniture store, was afflicted with multiple sclerosis. Paralyzed and home-bound, he would live another 36 years and never move his limbs. The store was lost. Money was scarce. In the mornings, Ernie and his two brothers would help lift their father from the bed to the wheelchair. Then they would gather up cakes and sandwiches their mother had been making since 4 a.m., and deliver them via streetcar to drugstores and society functions. It was the Depression. A nickel here. A dime there.
He wrote. He loved writing. He even considered music (and has written nearly 50 songs that have been recorded). But, in time, he fell in love with radio. His first broadcasting job was in 1946, with the Atlanta Crackers of the Southern League, Ponce De Leon Field. When they played at home, he called it all.


text:
Budget changes hit KiwiSaver's appeal
Term deposits and rental property remain the investment of choice for the majority of Kiwi's, while Budget changes have dented KiwiSaver's popularity, according to the latest ASB Investor Confidence Survey.
Tuesday, August 16th 2011, 10:02AM
kiwiSaver fell from 12% to 9% as the investment offering the best return, ranked behind term deposits, rental property and bank savings.
"The changes to KiwiSaver announced in Budget 2011 appear to have shifted investor perceptions of KiwiSaver," said ASB head of private banking and wealth management, Jonathan Beale.
"The swing in attitude can also be seen in the 6% drop in the number of people that think KiwiSaver will encourage New Zealanders to save for their retirement, from 75% to 69%."
However, the survey also found out of those using or intending to use KiwiSaver, a record 63% said it would be their main source of retirement provision, a percentage which has been slowly rising over the past year.
"For this reason we see the drop in KiwiSaver popularity as a downward blip in the short term."
Beale said it remained to be seen whether this 'blip' developed into a longer term trend, "but our feeling is that the success of KiwiSaver will see it pick up in popularity again in future."
The survey found an even split between investors expecting better or worse investment returns.
A total of 21% of investors felt term deposits offered the best value of all investment types, up two points from last quarter. Rental property climbed one point to 16%, followed by bank savings, steady at 12%.
Beale said the results indicated investors are incorporating their desire for security into their assessment of best returns, "and are still turning to term deposits and rental properties over other investments."
« Fidelity KiwiSaver fund hurt by market volatility Bubbles could attract KiwiSaver fly-by-nighters »
www.GoodReturns.co.nz


The doctors and nurses carry out surgeries throughout most of the opening hours. However, the staff take emergency telephone calls only between 12:30 and 13:30 daily.
Please note the surgery is closed on the first Wednesday of the month from 12:30 - 13:30 for staff training.
Medvivo is a local c onsortium of doctors and nurses who are based at Chippenham and they are responsible for all out of hours emergency medical cover from 18:30 to 08:00 Monday to Friday, all day and night Saturday, Sunday and bank holidays.
A doctor is on call for all of Devizes and the surrounding areas. Try to restrict your calls to genuine emergencies which cannot wait until normal surgery opening hours. Patients who are medically fit to do so will be asked to attend Chippenham hospital depending on the time of day.
Patients who are unwell will still be visited at home if, in the opinion of the doctor, they are not fit to travel.


Free CME conference! Earn up to 16.5 AMA PRA Category 1 Credits™, ABIM MOC Points, AAFP Credits.
Join us on November 17-18 and participate in clinical education that aligns to the National Quality Strategy (NQS) priorities. These priorities provide the framework for Triple Aim of better care, better health, at a lower cost.
Medical Education Exchange (MEDX) Primary Care Conferences are a two-day multi-topic CME conference series designed for the community-based primary care team, including physicians, physician assistants, and nurse practitioners.
Please use Google Chrome or Firefox to participate in Virtual Array on your computer.
To access the session evaluations and to claim credit during the webcast, you will need to enter the Order Number received via confirmation email upon registering for the webcast.
To continue, please follow this link to fill out a post survey.


text:
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
Guidance on building better digital services in government
What Is a "Terms of Service" and How Do I Get One?
Jonathan Rubin
Imagine this: You just found a great online tool that can help you do your federal job 100% better. You're all ready to download it and start conquering the world when someone asks, "Have you checked the Terms of Service?" You're not sure what they're talking about, what a Terms of Service is, or why you need one. Let's answer this and more in our Terms of Service Flowchart (click the image to the right to download your own PDF copy of this chart for reference) and our Terms of Service FAQ:
What are Terms of Service (TOS)?
Whenever you install iTunes or sign up for a site like Facebook or Twitter, at a certain point you have to click on a button and check a box that says something like "I agree to these Terms." These are the Terms of Service (or TOS), the rules companies require for doing business with them. Most people never read the rules. They just accept them and jump right into using the tool. All sorts of products have terms: social sharing sites, usability testing tools, or many of the mobile apps on your smartphone.
Why are Terms of Service a big deal?
When you agree to the TOS for a product as part of your government job, you are agreeing to a contract with the company. Those Terms may not impact you as a private citizen, but they could end up creating serious problems for the federal government, including:
Opening the government up to lawsuits or liability for unlimited damages (a.k.a. "Indemnification")
Giving up control over the content of your agency posts
Requiring government personnel to travel to the state where the company operates to deal with disputes
Allowing advertisements for private companies to run alongside government content—ads that might contain inappropriate words and images, or create the appearance of unfair endorsements
Do free products have Terms of Service, or just paid ones?
All products—whether free or paid—have terms that you must accept before using them. Many of the terms—such as those regarding advertising or altering uploaded content—apply whether or not there is money involved.
So what do we do about these Terms of Service?
The good news is that many companies are willing to negotiate their Terms of Service with the government to create an Amended Terms of Service for federal users, also known as a federal-compatible Terms of Service agreement. Here's a link to a flowchart explaining how to do this. Take a look.
OK. What should I do to get an Amended Terms of Service?
You'll need to know whether the tool is free or paid, because that will determine whether you should work with a Contracting Officer or not (again, see the flowchart). If a Contracting Officer is not involved, you'll then work with your agency lawyers (legal counsel) to create an Amended Terms of Service. Many agencies have done this successfully. The results—more than 70 completed Amended TOS—can be found on our federally-compatible Terms of Service agreements page.
Your legal counsel will take a look at the company's current TOS for the tool and identify any issues that could be a problem. She or he will then reach out to the company and ask them to modify their terms to meet federal needs. Often, the company will agree to the federal modifications your attorney proposes immediately. Other times, there is a back-and-forth as certain terms are added or deleted.
When it's done and an agreement is reached, one of two things will happen:
The company will post the terms to its website (ideally). This means you'll see these on the site when you sign up and open your account and start using the tool. Or…
The company will make special arrangements for your agency, and send you instructions on how to "agree" or "sign up" to the new terms.
How long does it take to reach an agreement on the TOS?
At best, a few weeks. However, it sometimes takes months or longer, especially if:
the company you're working with has no prior government exposure
the company is large and has a lengthy internal review process
there are many other tools ahead of you in line waiting for legal review at your agency.
Can someone help me with this?
Yes! GSA offers:
A list of companies that have already negotiated Terms of Service with a government agency, and a list of negotiated agreements. You may be able to use these as a starting point in your own negotiations.
A Model Terms of Service Agreement (MS Word, 55 KB) lists the major issues that need to be addressed. You can use it as a template, and modify as appropriate.
A list of TOS contacts at every agency who can help you. If your request is approved, your agency contact will be the one reaching out to the company, not you.
Help with negotiating Terms of Service agreements for free tools (not paid). If you are willing to take the lead in negotiations with a company, GSA can help. GSA is especially interested in helping with high-visibility tools that have wide application across the government. See our flowchart to see where GSA gets involved.
Why is GSA doing this?
In 2012, the Department of Justice, Office of Legal Counsel, issued a Memorandum on the subject of online TOS Agreements. Following DOJ's lead, in 2013, OMB issued a Memorandum warning agencies not to use online tools whose Terms of Service are incompatible with federal law, regulation or practice. OMB advised agencies to carefully review the terms regarding these products and services. This includes items your agency is using now and items you plan to use in future. OMB recommended that GSA assist agencies who are seeking a federally-compatible Terms of Service agreement.
Each agency is unique and operates under its own set of authorities, and GSA itself does not have government-wide authority to represent other agencies in this area. The good news is that a wealth of experience has been accumulated, which means you can build upon work done by GSA and other agencies to make things happen a lot faster.
What are some tips to a successful TOS negotiation?
Look at the company's TOS with your lawyer to identify any issues your agency may have before reaching out to the company. Know the deal breakers that you can't budge on.
Use the Model Terms of Service Agreement (MS Word, 55 KB, 5 pages, October 2011) as your starting point and tailor it to your needs.
Make sure your agency approves the use of the software or service for your job (be ready to discuss privacy, security, 508 requirements, etc.).
Help identify a point of contact at the company for your agency to work with.
Once you're done getting an amended TOS, share the good news with your community through blog posts on DigitalGov.gov and webinars through DigitalGov University or your Community of Practice.
Visit our main Terms of Service page.
Have feedback or questions? Send us an email »
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Experimental Angiostrongylus costaricensis infection in mice: immunoglobulin isotype responses and parasite-specific antigen recognition after primary low-dose infection.
Use of P-glycoprotein gene probes to investigate anthelmintic resistance in Haemonchus contortus and comparison with Onchocerca volvulus.
Int J Parasitol. 1998 Aug;28(8):1235-40.
Subclass-specific serological reactivity and IgG4-specific antigen recognition in human echinococcosis.
Trop Med Int Health. 1997 Aug;2(8):779-87.
Antigenicity and specificity of very low molecular weight Onchocerca volvulus polypeptides in the range 2.2-12.5 kD.
Trop Med Int Health. 1997 Jul;2(7):635-45.
T helper responsiveness in human Loa loa infection; defective specific proliferation and cytokine production by CD4+ T cells from microfilaraemic subjects compared with amicrofilaraemics.
Clin Exp Immunol. 1997 May;108(2):272-8.
The diverse expression of immunity in humans at distinct states of Onchocerca volvulus infection.
Geiger SM, Hoffmann W, Rapp J, Schulz-Key H, Eisenbeiss WF.
Filariidae: cross-protection in filarial infections.
Exp Parasitol. 1996 Aug;83(3):352-6. No abstract available.
Immunoregulation in onchocerciasis: predominance of Th1-type responsiveness to low molecular weight antigens of Onchocerca volvulus in exposed individuals without microfilaridermia and clinical disease.
Clin Exp Immunol. 1996 Aug;105(2):245-53.
Ivermectin-facilitated immunity in onchocerciasis; activation of parasite-specific Th1-type responses with subclinical Onchocerca volvulus infection.
Clin Exp Immunol. 1994 May;96(2):238-44.
Onchocerca volvulus provides ligands for the stimulation of human gamma/delta T lymphocytes expressing V delta 1 chains.
J Infect Dis. 1993 Nov;168(5):1241-7.
Experimental onchocerciasis in chimpanzees: cellular responses and antigen recognition after immunization and challenge with Onchocerca volvulus infective third-stage larvae.
Parasitology. 1993 Jul;107 ( Pt 1):87-97.
Characterization of a recombinant T cell and B cell reactive polypeptide of Onchocerca volvulus.
J Immunol. 1993 Apr 1;150(7):2931-44.
Efficacy of ivermectin in the treatment of concomitant Mansonella perstans infections in onchocerciasis patients.
Trans R Soc Trop Med Hyg. 1993 Mar-Apr;87(2):227-9.
Ivermectin-facilitated immunity in onchocerciasis. Reversal of lymphocytopenia, cellular anergy and deficient cytokine production after single treatment.
Clin Exp Immunol. 1992 Sep;89(3):407-13.
Specific and sensitive IgG4 immunodiagnosis of onchocerciasis with a recombinant 33 kD Onchocerca volvulus protein (Ov33).
Trop Med Parasitol. 1992 Sep;43(3):139-45.
Experimental onchocerciasis in chimpanzees. Antibody response and antigen recognition after primary infection with Onchocerca volvulus.
Schulz-Key H, Soboslay PT, Hoffmann WH.
Parasitol Today. 1992 May;8(5):152-3. No abstract available.
Experimental onchocerciasis in chimpanzees. Cell-mediated immune responses, and production and effects of IL-1 and IL-2 with Onchocerca volvulus infection.
J Immunol. 1991 Jul 1;147(1):346-53.
Ivermectin in the treatment of onchocerciasis: feasibility, compliance and efficacy of a mass treatment.
Bull Soc Pathol Exot. 1991;84(5 Pt 5):739-49. French.
The chemotherapy of onchocerciasis. XIV. Studies with mebendazole citrate.
Trop Med Parasitol. 1990 Dec;41(4):383-6.
Distribution of microfilariae of Onchocerca lienalis and Onchocerca gutturosa in the skin of cattle in Germany and their development in Simulium ornatum and Culicoides nubeculosus following artificial infestation.
Effect of ivermectin on the vertical distribution of Onchocerca volvulus microfilariae in the skin.
Trop Med Parasitol. 1990 Jun;41(2):165-8.
Observations on the reproductive biology of Onchocerca volvulus.
Ivermectin prophylaxis against experimental Onchocerca volvulus infection in chimpanzees.
Am J Trop Med Hyg. 1988 Jul;39(1):86-90.
Isolation and characterization of expression cDNA clones encoding antigens of Onchocerca volvulus infective larvae.
J Clin Invest. 1988 Jul;82(1):262-9.
Ivermectin effect on microfilariae of Onchocerca volvulus after a single oral dose in humans.
Trop Med Parasitol. 1987 Mar;38(1):8-10.


text:
Binibining pilipinas 2013 winners q&a book
Binibining pilipinas crowned its 50th batch of beauty queens sunday night, april 14, in a star studded goldenanniversary celebration held at. Heres is the full list of 20 binibining pilipinas candidates. In a press statement, the bb pilipinas charities inc said. The most prestigious pageant in the philippines for more than 50 years. The 24yearold dusky beauty from binangonan, rizal competed in binibining pilipinas in 20. Someone call a translator for the miss world pageant as janina san miguel actually won bb.
The year 2016 was another sterling year for the bb. At the end of the day, there is one and there will only be one binibining pilipinas gold. Its yet another big beauty pageant day tomorrow, october 3, 20, for us enthusiasts and of course for our very own 20 bb pilipinas tourism johanna cindy veron miranda as its now her turn to shine. With the finals night concluding last sunday, the set of winners were announced with a unanimous approval from pageant fans and the likes. And that if she is given the chance she would be thankful for the genes and the life that he help give her. Pia wurtzbachs farewell walk at binibining pilipinas 2016 with great results from the 2015 queens, the pressure is on for these 6 ladies.
Pilipinas international 20 joanna cindy miranda bb. The binibining pilipinas 2011 grand coronation night was held on april 10, 2011 at araneta coliseum in quezon city. Bb pilipinas 2017 final hot picks by missosology if theres one lesson to be learned from this years batch of bb pilipinas candidates, that would be to never underestimate anyone. Heres the questions given by the judges and the answers of the. The 50 official candidates of the 20 binibining pilipinas have been revealed thursday night in quezon city the candidates will win the following title of miss universe philippines 20,binibining pilipinasinternational 20 and binibining pilipinastourism 20. Fifty candidates participated in the 20 pageant, which was aired by. Click here to visit our frequently asked questions about html5 video. Binibining pilipinas reveals 40 official candidates for 2020. Yvethe marie avisado santiago as binibining pilipinas. Pia alonzo wurtzbach formerly known professionally as pia romero, is a filipinagerman. Binibining pilipinas 20 its golden winners, history. It was aptly dubbed as the binibining pilipinas gold as the pageant celebrates its 50th edition this year.
This year was a tough competition because a lot of the contestants exude beauty, grace, wit and confidence. Pilipinas 2015who are the top contenders inquirer lifestyle. Mary anne bianca garcia guidotti as binibining pilipinas international 2014. Pilipinas 20 winners bare themselves to inquirer entertainmentbeauty pageant writers marinel cruz, armin adina and editor bayani. Pilipinas 20 winners on their farewell walk youtube. Manila, philippines binibining pilipinas crowned its 50th batch of beauty queens sunday night april 14 in a starstudded golden anniversary celebration held at the araneta coliseum in quezon. Pilipinas 2014 coronation night asked questions to their designate candidates, the. Filbritish beauty crowned miss universephilippines 2017. Binibining pilipinas is the philippines most prestigious beauty pageant. Ariella arida miss universe philippines bea rose santiago bb. Binibining pilipinas 2014, the 51st edition of binibining pilipinas, was held on march 30, 2014 at the smart araneta coliseum, quezon city, philippines. Miss philippines is a national beauty pageant in the philippines that selects filipina representatives to compete in one of the big four major international beauty pageant.
The judges had a difficult time choosing their winners. Like most beauty pageant candidateswinners, joanne ended up entering the world of show business, doing movies and television. Pilipinas franchise of pageants, with a miss international win, a 1st runnerup finish in miss grand international, a 4th place finish in miss globe and miss universe, and top 15 finishes in. These eight candidates are likely to figure prominently in the winners circle come april 30th. Binibining pilipinas 2015 in question and answer portion part 1 duration. Our favorite binibining pilipinas international winners. Remember about that something white i mentioned in an earlier blog. Binibining pilipinas 20, the 50th edition of binibining pilipinas pageant billed as binibining pilipinas gold, was held on april 14, 20 at the smart araneta coliseum, quezon city, philippines. The 2015 binibining pilipinas candidates answer the miss universe. Every year, many people await patiently for the major beauty pageants, one including the pageant to start out the year, binibining pilipinas. During binibining pilipinas 20, she was named as the 1st runnerup.
Binibining pilipinas 2015 coronation of winners duration. In one of our earliest meetings with her during binibining pilipinas 2019, gazini confided that the binibining pilipinas pageant may help pave the way for her to meet her dad whom she never met. She was the second woman from india to be crowned miss universe, and has been the only delegate from india to win the crown since. She is one of the four filipinas to have won the miss universe. At the end of the pageant mary jean al shabrami lastimosa was crowned miss universe philippines 2014. Binibining pilipinas 2016 question and answer round. Taking a break from binibining pilipinas 2014 posts for a short update on miss world 20. Miss international and selects four other titleholders to participate in minor international pageants such as miss supranational, miss grand international, miss. Miss universe 20 gabriela isler of venezuela will sit as one of the judges of this years binibining pilipinas pageant and will assist in crowning the new set of winners. When binibining pilipinas, the countrys oldest and most prestigious. Xian lim on his favorite comic book heroes by dexter matilla.
Belofication aside, cindy, as she is now, is textbook. Soon to come is the coronation night of all 40 candidates which is to be held at the smart araneta coliseum in quezon city, manila on march 30, 2014. The new queens were crowned in the binibining pilipinas 2017. Xian lim on headstart july 25, 20 part 1 by criselda lorica. Wurtzbach joined the binibining pilipinas pageant three times before winning the binibining pilipinas. Pilipinas 20 winners ramp their title as they had their farewell walk. Not that my opinion matters but, if you may, i would like to present my insight of what transpired at the coronation night on the 15th of april 2012. Posts about binibining pilipinas 2014 written by iceskate3. Pilipinas tourism cindy miranda, miss universe 3rd runner up ariella arida, miss international 20 bea rose santiago and miss supranational 20 johanna datul. Pilipinas question and answer portion of the beauty pageant is one of the most crucial part during the coronation night as every answer from each contestant can make or break their chance of winning the crown. Wurztbach won first runnerup in 20, only to be shut out of the winning circle last year for. The neverending congratulatory messages have started pouring in.
Stella marquez araneta, has selected the 40 official candidates of binibining pilipinas 2020 during the final closeddoor screening at the new frontier theater on february 6, 2020. Here are the queens who will represent the philippines in. The binibining pilipinas 2017 winners were announced at the pageants coronation night on sunday, april 30, at the smart araneta coliseum. Miss universe philippines 20 ariella arida binibining pilipinas international 20 bea rose santiago binibining pilipinas tourism 20 joanna cindy miranda binibining pilipinas suprenational 20 mutya johanna datul 1st runnerup pia wurtzbach special awards bb. Before the winners were declared, the top 15 finalists went through a series of question and answers round. Before announcing the winners, the top 15 finalists went through a series of question and answer round, wherein the contestants were asked different questions by the jury. Recognizing the way ways to get this book pageant question and answer is. Best miss universe of all time catriona gray 2018 all q. Iza calzado, ms shamcey supsup and ms venus raj for doing an amazing job of hosting the event. The binibining pilipinas 20 had its press presentation last march 18 at the grand ballroom of the makati shangrila hotel where the girls also presented their national costume where the best one would win an award come finals night on april 14. The question and answer portion during any the beauty pageant is considered the most essential part of the competition since the contest is not only matters about beauty but brain as well. Best in national costume 37, maria teresita alaine baccay. The onesheets feature the monsterstudents mike wazowski, james p. Mar 28, 2017 celebrating the beauty queens who are not just pretty faces but also smart and accomplished see more ideas about beauty queens, pretty face and beauty.
Pilipinas franchise of pageants, with a miss international win, a 1st runnerup finish in miss grand international, a 4th place finish in miss globe and miss universe, and top 15 finishes in miss supranational and miss intercontinental. Megan young will be visiting colombia next month, according to an instagram post by mister world 2012 francisco escobar. Let me end this entry by sharing a video clip of a scene from the abscbn drama antholoy maalaala mo kaya when actress liza soberano played the role of pia wurtzbach. Best answerers in history of miss universe pageant. Right now there is a protest going on right outside here calling the miss. Back then she was a heavy favorite but only finished in the top 15. Inquirer super asks this years binibining pilipinas candidates how they. At the age of just 18, she won the binibining pilipinas in 1995 and representative the philippines in the miss universe pageant. By jo erlinda maufit winners of the 2017 binibining pilipinas from left 2nd runnerup kristel guelos, bb pilipinas globe 2017 nelda ibe, bb. Book of poems by imprisoned chineseswedish bookseller smuggled. Samanthas first foray in national pageants was in miss world philippines 20, won by megan young. Disneypixar has just shared eight new character posters for monsters university, the highly anticipated 3d prequel to the 2001 blockbuster, monsters, inc.
Pilipinas universe 2008 janina san miguel, miss universe 2010 4th runner up venus raj, miss universe 2011 3rd runner up shamcey supsup, miss universe 2012 1st runner up janine tugonon in the spirit of megan youngs miss world 20 win, we at manila speak would like to give tribute to the scores of young women who have blazed the path ahead of. Binibining pilipinas 2018 winners, special awards, highlights c. Binibining pilipinas 2015 question and answer round. Miss puerto rico janelee chaparro won the crown as the first miss grand international 20.
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Growing their own: Here's what 7 Bend restaurants are harvesting from their on-site gardens and serving up fresh for you!
The amazing on-site garden's at Bend's CHOW restaurant.
While Bend's location in the mountainous high desert makes it a great spot for skiing and hiking, it's not the world's greatest location for agriculture. Our chilly nights and dry climate means our growing season is about 90 days long—about half what you get in rainy parts of the state like Portland or Eugene.
But local gardens do yield some pretty impressive produce, particularly when they're located on the grounds of some of Bend's best dining establishments. Here's what's currently coming out of the ground and onto plates at some savvy Bend restaurants.
This cozy little restaurant on Newport Avenue is one of Bend's premier examples of locally-sourced, sustainable cuisine done right. Their impressive on-site garden provides much of the restaurant's produce, with nine raised beds and an additional 400 square feet of garden area. Currently, CHOW is harvesting baby bok choy, purple haze carrots, a variety of greens, basil, kale, spinach, zucchini, and patty-pan squash. Check their specials board for seasonal offerings like the locavore omelet, seasonal salads, or a variety of Asian dishes starring the bok choy and carrots.
Delicious veggie salad at CHOW, with ingredients straight from their garden!
My favorite way to dine at CHOW is simply to ask my server to have the chef to surprise me (offering up any dietary restrictions/preferences beforehand, of course). I've never been disappointed, particularly this time of year when their garden is teeming with goodies. The scramble is a particularly good choice for breakfast or lunch, or ask for a salad prepared with all their garden bounty. They're open for breakfast and lunch seven days a week.
Worthy's on-staff garden consultant, Lisa, tends to the veggies.
One of Bend's newest breweries is also one of the greenest, most agriculturally-focused. Worthy Brewing has its own hop growing yard, which doubles as a hop research facility for Oregon State University. Besides hops, they also grow a wide range of produce they use for creating tasty dishes in the kitchen. Right now, they have an abundance of cucumbers, zucchini, sorrel, basil, tomatoes, green onions, and cilantro. The tomatoes and cucumbers end up in a variety of salads, while the zucchini is a side dish accompanying the blackened salmon entrée. The herbs round out a lot of Worthy's wood-fired pizzas.
Ask your server about ever-changing daily specials, which always make good use of their garden veggies. If you swing by on a Friday night, don't miss their prime rib special, which comes complete with an array of their own garden bounty. The Worthy IPA is my personal fave, so grab a pint to go with whatever you choose from the menu.
These two Westside hotspots are adjacent to each other on Columbia Avenue, which makes it handy for them to share a lovely pair of gardens dubbed, "Herban Garden" and "Shasta Garden." Ripe and ready for picking, they have broccoli, kale, dill, cilantro, and culinary herbs like chives, flowering oregano, sage, lemon balm and lovage. Their tomatoes and potatoes should be ripening in a few weeks. Most of the produce is distributed to employees in what they call their, "employee health plan," but some of it ends up on the menu, too.
The herb spiral shared by Real Food Street Bistro and Baked.
Chef Michael McCann of Real Food Street Bistro uses the dill in the brine for his own housemade pickles served at this cute little street cart, and the cilantro and daikon radishes make it into the housemade kimchi. Baked. owner Gordon Benzer also uses gardening offerings in some of his baked goods, as well as preparing meals to serve folks who volunteer to work in the garden. Stop by for a loaf of bread at Baked. or a cup of soup at Real Food, then meander the gardens and admire some of the new additions like fruit trees and a bee box.
The foccacia and the caprese salad at Ariana's both prominently feature their home-grown herbs.
Arguably one of Bend's best fine-dining options, Ariana Restaurant makes the most of its cozy patio with an impressive little herb garden. They currently have rosemary, sage, thyme, basil, lemon balm, lavender, and hops. Herbs like rosemary and thyme are used in the house-baked foccacia and with roasted meats like porchetta, which is served as a special from time to time.
Lavender flowers are picked and dried and used in lavender ice cream (a current special) and the Provence cocktail, made with gin, lavender, and honey-infused syrup. The basil plays a starring role in the restaurant's caprese salad, which is one of the best I've ever tasted. If the weather's warm, let them know when you make your reservation that you'd like a spot next to the herb garden for an up-close-and-personal look at where your food comes from.
Gorgeous herbs grow in the sunny courtyard at Jackalope.
Another incredible fine-dining restaurant with an amazing array of fresh veggies and herbs, Jackalope Grill manages to fit a whole lotta garden into their little courtyard. Beautiful tiered planters and boxes feature lettuce, kale, cucumbers, and tomatoes, and Jackalope's impressive selection of herbs go straight into the kitchen to produce fresh and unique cuisine.
The garden boxes also help create some of the best ambiance you'll find in outdoor dining around Bend.
I'm a huge fan of the salads at Jackalope, and it's easy to see why when you survey their garden boxes. Unique offerings like nasturtiums and shiso add a spicy kick to greens, and fresh herbs are earmarked for housemade dressings. Try their basil cucumber martini for a super-fresh cocktail option, then order a salad of fresh field greens to get things started right. Though it doesn't come from their garden, I guarantee any of their beef-based entrees will leave you swooning.
The Farmer's Market cocktail at Dojo.
While Dojo's space in the middle of Downtown Bend doesn't lend itself to the grow-your-own approach, they do have the advantage of being ten feet away from the Farmer's Market on Wednesday afternoons. They make the most of this by browsing the market the moment it opens and creating a drink specials around whatever's fresh that week. The lineup currently boasts a lot of peach and melon-centric offerings, so swing by for a mid-afternoon happy hour.


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Investigation underway into cause of Crayfish Plague on River Bruskey, near Ballinagh, Co Cavan
The National Parks and Wildlife Service (NPWS) of the Department of Arts, Heritage and the Gaeltacht and Inland Fisheries Ireland are investigating the cause of death of large numbers of dead freshwater crayfish, which have been found in the Bruskey/Erne River at Killydoon, near Ballinagh Co Cavan. The kill affected White-clawed Crayfish Austropotamobius pallipes along a short stretch of the Bruskey River where over 600 dead crayfish were found. Fish and other freshwater animals are not affected.
Preliminary results, using DNA analysis, indicate the cause of the kill is Crayfish Plague, a water-borne disease. The situation is of concern to both Inland Fisheries Ireland and the NPWS. Investigations are being carried out to establish how the disease got to the Bruskey River and whether it has spread from the initial area of infection.
It appears that either the disease was accidentally introduced on contaminated equipment (e.g. wet fishing gear or boots or boats used recently in affected waters in the UK or elsewhere) or else that non-native species have been illegally introduced to the area and have now passed the disease to the White-clawed Crayfish.
If the disease outbreak was accidentally introduced on contaminated equipment, then containment may be possible, but if non-native crayfish have been introduced then the disease is likely to become established with severe and probably irreversible ecological impact on freshwater fauna and flora.
The NPWS and IFI are asking anglers and members of the public to take precautionary measures to help stop the spread of the disease. People are asked to alert the authorities to any reports of mass mortalities of crayfish, sightings of unusual crayfish (e.g. red claws, large size) and in particular to dry or disinfect boots or angling equipment before moving from one water to another.
The crayfish plague disease can be carried on wet equipment so ALL equipment (clothing and fishing gear) that has been in freshwater must be treated with a disinfectant and then completely dried before moving to another area. This will avoid the accidental spread of the disease to other areas.
The White-clawed Crayfish is the only freshwater crayfish species found in Ireland and is present in lakes, rivers and streams over much of the island. Throughout its European range, this species has been decimated by the impact of Crayfish Plague which spread to Europe with the introduction of North American species of crayfish. Until now, Ireland has been considered free of the disease and is the only European country without any established non-native crayfish species.
Many American crayfish species are resistant to Crayfish Plague, but can act as carriers of the disease which is rapidly fatal when passed to the White-clawed Crayfish. The combined impact of the introduced crayfish species (which may out-compete the smaller native crayfish) and Crayfish Plague have completely eliminated the White-clawed Crayfish from much of its European range, leaving Ireland as the last stronghold of the species. The species is protected under Irish Law and the EU Habitats Directive. It is illegal to introduce any non-native species of crayfish to Ireland.
If Crayfish Plague becomes established there is a high probability that the White-clawed Crayfish will be eliminated from much of the island. Furthermore, if non-native crayfish are found to be established in Ireland, this could have a severe impact on habitats (e.g. destabilising canal and river banks by burrowing) and other freshwater species, such as salmon and trout fisheries. However there is no evidence to date that non-native freshwater crayfish have been introduced to Ireland.


text:
package com.structurizr.analysis;

import com.structurizr.model.Component;
import com.structurizr.model.Container;
import org.springframework.data.jpa.repository.JpaRepository;
import org.springframework.data.repository.CrudRepository;
import org.springframework.data.repository.Repository;

import java.lang.reflect.Modifier;
import java.util.HashSet;
import java.util.Set;

/**
 * A component finder strategy for Spring repositories (classes annotated @Repository,
 * plus those that extend JpaRepository or CrudRepository).
 */
public final class SpringRepositoryComponentFinderStrategy extends AbstractSpringComponentFinderStrategy {

    public SpringRepositoryComponentFinderStrategy(SupportingTypesStrategy... strategies) {
        super(strategies);
    }

    @Override
    protected Set<Component> doFindComponents() {
        Set<Component> components = new HashSet<>();

        components.addAll(findAnnotatedSpringRepositories());
        components.addAll(findSpringRepositoryInterfaces());

        return components;
    }

    private Set<Component> findSpringRepositoryInterfaces() {
        Set<Component> componentsFound = new HashSet<>();
        Set<Class<?>> componentTypes = new HashSet<>();

        Set<Class<?>> types = getTypeRepository().getAllTypes();
        for (Class<?> type : types) {
            if (type.isInterface()) {
                if  (
                        Repository.class.isAssignableFrom(type) ||
                        JpaRepository.class.isAssignableFrom(type) ||
                        CrudRepository.class.isAssignableFrom(type)
                ) {
                    componentTypes.add(type);
                }
            }
        }

        for (Class<?> componentType : componentTypes) {
            if (!includePublicTypesOnly || Modifier.isPublic(componentType.getModifiers())) {
                final Container container = getComponentFinder().getContainer();
                Component newComponent = addComponent(
                    container,
                    componentType.getSimpleName(),
                    componentType.getCanonicalName(),
                    "",
                    SPRING_REPOSITORY);

                if (newComponent != null) {
                    componentsFound.add(newComponent);
                }
            }
        }

        return componentsFound;
    }

    private Set<Component> findAnnotatedSpringRepositories() {
        return findInterfacesForImplementationClassesWithAnnotation(
                org.springframework.stereotype.Repository.class, SPRING_REPOSITORY);
    }

}

redpajama_set_name: RedPajamaGithub


text:
Interstate travel, tourism activities allowed when 90% of adult population vaccinated: Malaysia PM Ismail Sabri
Johor will enter phase two of the National Recovery Plan from Sep 24, 2021.
People dine at a restaurant in Langkawi, Malaysia on Sep 13, 2021. (Photo: Reuters/Lim Huey Teng)
Vincent Tan
22 Sep 2021 09:18PM (Updated: 22 Sep 2021 09:56PM)
KUALA LUMPUR: Interstate travel and tourism activities will be allowed once 90 per cent of Malaysia's adult population is fully vaccinated.
The decision was announced by Prime Minister Ismail Sabri Yaakob in a statement on Wednesday (Sep 22).
"Opening of tourism centres, islands or tourism areas, as well as interstate activities, will be allowed on condition that 90 per cent of adult vaccination rate is achieved, based on the data and analysis by the Ministry of Health," he said.
As of Tuesday, 80.2 per cent of the adult population in Malaysia have been fully vaccinated, according to data provided by the Special Committee on COVID-19 Vaccine Supply.
"I believe many cannot wait to return to their hometowns to meet their family after so long. God willing, this 90 per cent target is expected to be achieved in just two to three weeks' time," the prime minister added on his Facebook.
Langkawi travel bubble: Airlines, hotels see positive reception but some residents wary of COVID-19 setback
In his Wednesday statement, Mr Ismail Sabri said tourism centres and activities such as zoos, farms, aquariums, scuba diving and fishing would be allowed in all four phases of the National Recovery Plan (NPR), beginning Oct 1.
All operators and visitors must be fully vaccinated, he said.
In addition, spas, wellness centres and massage centres would also be allowed to operate from Oct 1, provided that the operators and customers are fully vaccinated.
On the retail side, grocers, mini markets, restaurants and petrol stations would be able to operate from 6am until midnight from Thursday onwards, Mr Ismail Sabri said.
Malaysia reported 14,990 COVID-19 cases on Wednesday, bringing the cumulative total to over 2.14 million cases. There have been about 24,000 deaths.
On Sep 16, Langkawi in Kedah reopened to local tourists in the country's first domestic travel bubble, months after an interstate travel ban was imposed to curb the spread of COVID-19 infections.
80% of Malaysia's adult population fully vaccinated against COVID-19: PM Ismail Sabri
JOHOR ENTERS PHASE 2 OF NATIONAL RECOVERY PLAN
The prime minister also announced that Johor would transition from phase one to phase two of the NRP from Sep 24 onwards.
According to the National Security Council, the inter-district travel ban within the state will be lifted.
Fully vaccinated individuals can also perform their prayers in mosques and non-Muslim houses of worship, subject to standard operating procedures set by the state religious authorities or the Ministry of National Unity.
Dining-in is also permitted, with a 50 per cent capacity for each table. Tourism activities involving hotels and homestays within the state are also allowed, as are hiking and picnicking for fully vaccinated individuals.
Meanwhile, Negeri Sembilan would enter the fourth phase of the NRP and Pahang would move into phase three, Mr Ismail Sabri said.
Under the NRP, hospital admission rate, intensive care unit occupancy and vaccination rate are the key indicators determining the transition from one phase to another.
BOOKMARK THIS: Our comprehensive coverage of the COVID-19 pandemic and its developments
Download our app or subscribe to our Telegram channel for the latest updates on the coronavirus pandemic: https://cna.asia/telegram
Source: CNA/vt
Malaysia tourism Ismail Sabri Yaakob COVID-19 vaccination
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