text:
HOW TO STAY
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You are here: Home › Our Stories › Giving Hope For A New Life
Giving Hope For A New Life
A Mother's Story of Thanks
by: Mindy Mooney
About four days after my son Corrigan was born, he began having seizures and showing other signs of distress.
Corrigan was diagnosed with a rare genetic Urea Cycle Disorder. Two treatment options were available: a lifetime of severely restricted diet and strong medications or an organ transplant. His medical team felt that diet and medication would be the best course of action and we hoped it would be enough to manage Corrigan's illness.
Sometimes, diet and medications weren't enough to prevent a crisis, though. During a crisis event, Corrigan's body flooded with brain damaging toxins. Rescue medication would stop the crisis, but each event left him depleted.
Fear of not catching a crisis in time – which would result in Corrigan suffering from more severe brain damage, coma, or death – constantly hung over us. Simple things like a common cold, daily stress, too much exercise or even growing would trigger these events, wreaking havoc on Corrigan's system.
For ten years we navigated this precarious balancing act, until puberty threw Corrigan into metabolic instability. After five crisis events in four months, transplant became the only option to save his brain and his life.
Healing came in the form of a lifesaving liver transplant, but brought with it a new hurdle. Transplant protocol required that we not live more than an hour away from the hospital while Corrigan's body adjusted to his new organ. Willing to do anything to save our son's life, we agreed, despite living 2.5 hours away from the hospital.
We couldn't afford to rent a home or stay in a hotel nearby. If not for the Ronald McDonald House of Washington, DC, we would have had to sleep in our car for two months.
The first time we visited the Ronald McDonald House of Washington, DC, it just felt like home.
Life is ugly and beautiful. Sometimes in the same 24 hours. Sometimes hourly. I don't understand why we have so many ugly parts in ours compared to others but I'm so incredibly thankful for the beautiful ones. And I'm so thankful for Ronald McDonald House Charities of Greater Washington, DC, just 5 miles from the hospital.
The Ronald McDonald House allowed my husband to go "home" each evening and sleep in a bed, instead of the cot in Corrigan's hospital room. He could shower, grab food lovingly prepared by volunteers, regroup, recharge, and return to us the next morning bearing coffee, breakfast, and the smile we all needed to keep going.
The first time Corrigan was released from the hospital after his transplant, he was on 16 medications and it was more overwhelming than taking him home as a newborn. It was such a relief to be at the Ronald McDonald House, just 5 miles away from his medical team.
Thanks to a generous organ donor, my son's life has been changed in so many ways. Corrigan no longer has to be careful about what he eats and I no longer have to fear germs or viruses or outdoor activities that might have burned up too many calories for my boy!
Corrigan's journey taught us to never give up hope. Hope for a better day, hope for another smile, hope for tomorrow. Ronald McDonald House Charities of Greater Washington, DC gives families like ours a place to find strength, comfort, and hold on to our hope. Thank you for your support.
990 [PDF: 2 MB]
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The following trademarks used herein are owned by McDonald's Corporation and its affiliates; McDonald's, Ronald McDonald House Charities, Ronald McDonald House Charities Logo, RMHC, Ronald McDonald House, Ronald McDonald Family Room and Ronald McDonald Care Mobile.
RMHC of Greater Washington, DC is recognized as a public charity under Internal Revenue Code section 509(a) and has 501(c)(3) status. Donations to RMHC of Greater Washington, DC are deductible. Donors should consult their tax advisor for questions regarding deductibility. A copy of the RMHC of Greater Washington, DC determination letter is available upon request.

redpajama_set_name: RedPajamaCommonCrawl


We will be holding our annual Plant Sale on Saturday 19th May from 10am – 12pm and Newgate Nurseries will again be our supplier. All the plants are of top quality and are being sold at very competitive prices.
As last year, hanging basket refills are available. If you require these, please leave your empty hanging basket labelled with your name at the school office along with your order. The last day for ordering these is Friday 27th April. There is also a wide variety of vegetable plants and strawberries available.
Order forms can be found on the school website and should be returned to school by Friday 4th May, unless you require a hanging basket, in which case you need to return your order form to school no later than Friday 27th April, as these are planted to order. Please could you pay for all plants WITH your order.
All orders of plants will be ready for collection on Saturday 19th May between 10am and 12pm. There will also be a large selection of bedding and basket plants available to purchase on the day. Refreshments will be available.
In the event of any queries, please contact the school office (Tel: 01772 613112).
Many thanks for your support. We look forward to seeing you on the day.


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Absolutely agree. We have four and half years of Tory govt to look forward to, an articulate opposition asking searching questions is what's needed right now.
If Labour elect an anti-austerity candidate, there will also be support from SNP, Plaid and Green MPs in some votes, not enough to overturn a Tory majority following the Party whip, but enough to do so on some free votes and certainly enough to really open a proper debate rather than upholding the hopeless right of centre consensus.
Agree totally with your first paragraph. Not so sure about the second. I still think a Corbyn leadership will see a flight of "new Labour" MPs away from the party. I certainly don't think the Parliamentary Labour Party will suddenly transform into 232 left-wing Corbyn followers.
I mean, as a group the Labour Party decided to abstain from the social welfare vote (on the grounds that "the country voted for it"... I wanted to grab each one of the abstainers by the lapels and shake them while shrieking "not the people who voted for you! The ones who elected you didn't vote for it! They very specifically opposed it! And that's why they voted for you... to oppose it!") Do you really think they will unite behind an unabashed leftist; behind someone who, when faced with the question "Are you a Marxist", doesn't scoff and act offended at the very idea, but takes the question seriously and provides a nuanced response?
I like Corbyn. A lot more than I thought I would when people first started talking about him as a serious contender. And while it may be a good thing in the long run; there's no doubt in my mind that Labour will lose more than a few MPs if he is elected. Perhaps not on day one... but by this time next year I'll be surprised if there are more than 180 Labour MPs.


I've never heard of this series! I just went and goodreads the first one now I'm totally keen to get my hands on it! I'm glad you loved the book so much!!
Thanks, Amy! This book is a really good Fantasy read. If you like fantasy and YA then this is an excellent read.


text:
Published: 0352 GMT August 22, 2018
Russia will respond to groundless US sanctions: Ryabkov
Russia has said that the latest round of US sanctions imposed against Moscow is "groundless" and will evoke a response.
On Tuesday, Russian Deputy Foreign Minister Sergei Ryabkov stressed that the sanctions introduced over alleged hacking and illegal oil products supply to North Korea were introduced under a "false pretense."
The latest US sanctions are based on "malicious insinuations" and a "hardheaded, narrow-minded and aggressive approach by the US," he added.
"The United States is seeking to push its anti-North Korean policy through the United Nations Security Council Committee, insisting on expanding its sanction lists. It won't work," he stressed.
Earlier in the day, United States imposed sanctions on two Russians, one Russian company and one Slovakian company for aiding another Russian company avoid sanctions over the country's alleged cyber-related activities.
It also sanctioned two Russian shipping companies and six ships over claims of transferring refined petroleum products to North Korean vessels.
"Ship-to-ship transfers with North Korea-flagged vessels from Russia or elsewhere of any goods being supplied, sold, or transferred to or from (North Korea) are prohibited under the UN Security Council resolutions on North Korea and are sanctionable under US law," US Treasury Secretary Steven Mnuchin said in a statement.
"Consequences for violating these sanctions will remain in place until we have achieved the final, fully verified denuclearization of North Korea," Mnuchin added.
"Though Russia's malign activities continue, we believe its adventurism undoubtedly has been checked by the knowledge that we can bring much more economic pain to bear using our powerful range of authorities," said acting Deputy Treasury Secretary Sigal Mandelker
"We will not hesitate to do so if its conduct does not demonstrably and significantly change," Mandelker added.
The US has already introduced several rounds of sanctions against the government of President Vladimir Putin for what it calls Russia's meddling in the US Democratic process and its involvement in the Ukraine conflict.
Meanwhile, Britain's new foreign secretary, Jeremy Hunt, is set to push the United States into slapping tougher sanctions on Russia, in response to Moscow's "malign" behavior around the world.
Following the remarks Russian Foreign Minister Sergey Lavrov said that the UK trying to dictate foreign policy to the US and the European Union.
"Our British counterparts have pretty high self-esteem," he said.
"The country, which is leaving the EU as part of Brexit, is trying to dictate foreign policy to the EU, and now it turns out that London wants to dictate foreign policy with regard to Russia to Washington as well," he added.
US-based tech giant Microsoft also accused Russia of trying to launch cyber attacks on the US Senate.
Hours after the Microsoft report was released, the Kremlin said it did not understand allegations from the US corporation and that they lacked evidence.
"We don't know what hackers they are talking about," Kremlin spokesman Dmitry Peskov told reporters at a news conference in Moscow on Tuesday.
"... Who exactly are they talking about? We don't understand what the proof and the basis is for them drawing these kinds of conclusions. Such information (proof) is lacking," he added.
Russia's Foreign Ministry denounced Microsoft's accusations in a statement and said, "It is regrettable that a large international company, which has been working in the Russian market for a long time, quite actively and successfully, has to take part in a witch-hunt that has engulfed Washington."
groundless
Ryabkov
China, Russia warn US of consequences over sanctions
At least 20 killed in two road accidents in Iran
Iran to keep uranium enrichment at 4.5% level for now
UN concerned by US curbs on Iranian FM in New York
Zarif: Door 'wide open' to negotiation if Trump lifts sanctions
Top EU diplomat: Nuclear deal parties prefer more diplomacy


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We at Premier Office Furniture are committed to offering our Retail Customers a product selection wide enough to furnish a whole office requirement, available "off the shelf" for rapid delivery. All Rapidline products are selected from Sedex compliant factories around the globe and are supported by full commercial warranties.


Thanks to our working relationship with the Mayo Clinic, iMD now has hundreds of new patient resources concerning sexual health topics. To learn more, visit welcome.imdhealth.com. If you already have an iMD account, sign in at app.imdhealth.com to explore some of the new topics listed below. Click here to get your free iMD account.


We saw in one of the recent articles of this series that Language Arts is often present in other subjects. With math, It is somewhat the opposite. Mathematical notions might be present but are more difficult to bring out, unless working by project and intentionally implementing mathematical applications.
If you use a workbook for math, save the table of contents which presents the concepts seen during the year. You can also keep tests when there are some at the end of a section or chapter. Exercise pages that represent each concept covered can also be used if there are no tests.
If you don`t use a math workbook, faithfully take note of mathematical concepts covered throughout the year, whether through projects or with websites. More and more families choose to follow online programs to study math. This approach can be tricky to document in a portfolio depending on how the website is constructed.
Nonetheless, it is still possible to document this approach. Websites sometimes have progression charts. You can print these pages to save in your file. When the site has printable pages, print some in the beginning, middle, and end of the year so that progress is evident. If the website used does not contain tests, it is possible to use another website in order to find placement or evaluation documents that can be printed and completed to demonstrate the student's competency in the subject. You can also take screenshots or even photos of your child doing exercises with manipulatives. Of course, you can also create your own tests to evaluate progress in all the concepts seen throughout the year.
For Québec families, we also recommend including a Learning and Evaluation Situation in the portfolio. The Learning and Evaluation Situations are complex, multi-step learning tools that demonstrate a student's understanding of mathematical concepts. That being said, outside of the school system they are not easy to find in English. At the very least, be sure to include situational problems in your portfolio, since they are considered a crucial part of math in Québec.
There are certainly many ways to convey and to express the learning and progress made in math. Keeping good records and including samples of work will communicate your student's accomplishments.


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Rounding-up Canada's Digital Currency Regulatory Player Landscape
Jack FilibaApril 19, 2018
For the new and largely uncharted digital currency industry, it often seems like regulation is a potential threat to the landscape's growth. However, in countries like Canada, most major regulatory bodies are yet to enact changes that would stifle the industry's innovative nature.
While this could change in the future, understanding Canada's regulatory players and their motivations can help eliminate some of the fear and uncertainty that investors experience.
The OSC looks to innovative regulation
With bustling blockchain hubs like Toronto and Ottawa under its jurisdiction, the decisions that Ontario regulators make could have lasting effects on Canada's status as a blockchain leader.
Like most of the country, Ontario is yet to take firm action either against or in favour of digital currencies, instead taking the sensible approach of waiting to see how the industry develops.
However, with the Toronto Stock Ventures Exchange recently receiving listings from digital currency mining companies like Hut8, and TMX Group subsidiary, Shorcan DCN, partnering with Paycase Financial, it is possible that a new sense of urgency was created.
When it comes to digital currencies, more mainstream involvement increases the need for digital currency regulation. Bodies like the OSC aim to protect retail investors, and hope to find compromise with the digital currency landscape.
"The OSC will continue to foster new ways to raise capital and invest, while focusing on potential investor protection issues arising from cryptocurrency and blockchain-related developments," it stated.
The OSC recently stated that it will make innovative digital currency regulation a key focus for the 2018-2019 financial year, and aims to deliver on guidelines that help businesses and do not stifle blockchain innovation.
The Canadian Revenue Agency looks to tax gains
Taxes are an important topic of discussion for investors participating in the digital currency landscape. Historically, tax regulation for digital currency investors is far from clear, with both businesses and individuals alike left attempting to comply to the best of their abilities.
The Canada Revenue Agency (CRA) is the federal agency that administers the country's tax laws. In 2013, the CRA issued a later stating that digital currencies were not legal tender, instead calling them a commodity.
In a more recent speech made in December 2017, Bank of Canada governor Stephen Poloz addressed how individuals should go about considering digital currency gains and losses for tax purposes.
"Characteristics vary widely but, generally speaking, they can be thought of as securities. The Canada Revenue Agency agrees," he said. "That means, if you buy and sell them at a profit, you have income that needs to be reported for tax purposes."
The CSA takes a measured approach
In a December 2017 press release, the Canadian Securities Administrators (CSA) intended to "remind dealers and investors of the inherent risks associated with products linked to cryptocurrencies."
The CSA is the council of the securities regulators of Canada's provinces and territories, tasked with harmonizing regulation for Canada's capital markets. In the press release, the CSA stated that it will continue to follow developments surrounding the digital currency industry, advising investors to their due diligence before investing.
As the CSA stated, digital currencies are largely unregulated despite often being traded on regulated exchanges. This especially the case for digital currency future contracts, the CSA explained.
"More specifically, the underlying value of these futures contracts is based on trading occurring on markets for cryptocurrencies which are largely unregulated," said CSA Chair Louis Morisset.
Previously, CSA chairman and Binary Options Task Force investigator for the Manitoba Securities Commission, Jason Roy, praised Facebook's decision to ban digital currency ads, suggesting that Google should do the same.
While Google banned digital currency ads in March 2018, it is unclear if the decision was due to external pressure. Further, it is not clear if banning digital currency ads will actually harm the industry in the long-term.
The FCNB wants investors to be cautious of bad actors
The Financial and Consumer Services Commission New Brunswick (FCNB) recently made its desire to protect investors from fraudulent actors operating in the digital currency space. These fradulent actors attempt to leverage the industry's popularity to deceive investors, at the expense of honest blockchain and digital currency projects.
"Canadian securities regulators are monitoring the cryptocurrency environment because investors are being targeted more and more by fraudsters online to invest in cryptocurrencies and related financial "products," said Jake van der Laan, FCNB's director of enforcement and chief information officer, in a statement to Coinsquare News.
The FSNB's warning follows the pattern of regulatory bodies advising investors of the possibility of digital currency scams, while making sure not to create a false impression of the industry as a whole.
External pressure on the Bank of Canada from the BIS and G20
Canada is not alone in the discussion of how to appropriately react to the popularity of digital currencies. Recently, digital currency innovation was an important topic of discussion for 2018's G20 summit, which brought together financial leaders from participating countries to discuss the landscape.
The result was a call for measured digital currency regulation suggestions by July 2018, which many in the community saw as good news for the industry.
Further, the Bureau of International Settlements issued a statement warning countries against launching their own state-backed digital currency. The statement praised the disruptive nature of the industry, but took a cautious approach in instructing countries interested in launching state-backed digital currencies.
Overall, breaking down Canada's regulatory landscape reveals a seeming lack of intent to impose regulation that could stifle the industry. As both Canada and the world at large look to contextualize and appropriately react to the landscape, investors and pioneers hope for a measured approach that does not come at the expense of potentially world-changing technological innovation.
Image credit: Nick Youngson CC BY-SA 3.0
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Madonna Club
Madonna Posts on Fanpop
Madonna: I want a baby Jesus
posted by Joy3570
Madonna is trying for a baby with her toyboy lover Jesus Luz.
The Queen of Pop - who already has four kids - has consulted doctors about conceiving another child at the age of 51, pals said.
Brazilian Jesus, who at 22 is less than half Madge's age, has told her that becoming a father would be "his greatest adventure".
She is said to have agreed he would make a "fantastic dad" and told friends: "I have endless love in my heart for another child."
Madge already has daughter Lourdes, 13, by Carlos Leon and son Rocco, nine, by ex-husband Guy Ritchie.
She is also mum to her adopted Malawian orphans David Banda and Mercy James, both four.
A close pal, who calls Madonna by her preferred nickname Em, said: "Em says motherhood is her greatest achievement and the most fulfilling thing in her life.
"She knows that, at 51, it's going to be harder to conceive naturally. But she is Olympic-athlete fit and is ready for the challenge."
Madge has been with Jesus for more than two years, meeting him during a photo-shoot in Brazil shortly after she divorced Sherlock Holmes movie director Guy, 41. The pal added: "Jesus is very religious and deeply in love with her.
"He adores her kids but has always wanted a child of his own.
"He told Em fatherhood would be his greatest adventure, and that he wanted to go on this journey with her."
The superstar has often talked of her love of motherhood. She has said "all the money in the world" would not bring her the happiness of a family.
source: thesun.co.uk
Madonna lady gaga
added by doraaaayeah
"Glee" on Madonna episode
Wanna know the best time to hit up a TV producer for spoilers? Take it from me, it's when they smell a Golden Globe coming. Read on and feast on the scoopapalooza Ryan Murphy gave me just minutes before Glee's big victory last night…
The upcoming Madonna episode deserves to be called "very special." "It's big… huge. We're shooting it now. It's got like 10 numbers in it, and the production value is very big. We adore her and worship her, so when I'm directing, I'm always like, 'Do it for Madonna.'" (Ed. note: Murphy wouldn't say which Madge tune Jane Lynch's Sue would be doing, but I can confirm that it's "Vogue.")
Source: Entertainment Weekly
Madonna with Sheryl Crow, Shania Twain and Ricky Martin at the Grammy Awards (February 24 1999)
Madonna performing 'Nothing Really Matters' at the Grammy Awards (February 24 1999)
Source: http://www.sexydesktop.co.uk/madonna.htm
Source: http://www.syndrome-madonna.com/
Madonna- Photo shott for Interview May 2010
Madonna photographed by Joe Bangay in London (1983)
Source: http://www.madonnashots.com/
Source: http://www.madonna.com/
added by gymnastlover
Source: http://justjared.buzznet.com
The Madonna Club
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This art consists of three 16" Wide x 20" High canvases. Overall, the dimensions are 48" Wide by 20" High if you have no space between the canvases.
As an artist, I sometimes want to depict tangible objects in an abstract way, create landscapes or sunsets still recognizable, but also very abstract. But now I want to really express my emotions with the paint and with color and get it on the canvas without contemplating the interpretation of the work. I just want to get the emotion on the canvas. That means 'letting go'. So this is the first time in a very long time, that I have just let it go and painted what I was feeling and I loved the entire experience. So here is Pool Party! because even though summer is ending there's got to be time for just one more party! This abstract, contemporary art is made of 3 canvases and displayed here separated by about 3/4" just to illustrate an example of how it can be displayed. Each of the 3 canvases is 16" wide x 20" high and 1.5" thick. All the sides are painted black and all surfaces covered with a satin varnish. Each painting is ready to hang!


text:
#ifndef _IOKIT_IODATAQUEUE_H
#define _IOKIT_IODATAQUEUE_H

#ifndef DISABLE_DATAQUEUE_WARNING
#warning "IODataQueue is deprecated due to security issues in its interfaces, please use IOSharedDataQueue instead"
#endif

#include <libkern/c++/OSObject.h>
#include <libkern/OSTypes.h>
#include <mach/port.h>
#include <mach/message.h>

typedef struct _IODataQueueMemory IODataQueueMemory;
class IOMemoryDescriptor;

struct _notifyMsg {
    mach_msg_header_t h;
};

/*!
 * @class IODataQueue : public OSObject
 * @abstract A generic queue designed to pass data from the kernel to a user process.
 * @discussion The IODataQueue class is designed to allow kernel code to queue data to a user process.  IODataQueue objects are designed to be used in a single producer / single consumer situation.  As such, there are no locks on the data itself.  Because the kernel enqueue and user-space dequeue methods follow a strict set of guidelines, no locks are necessary to maintain the integrity of the data struct.
 *
 *
Each data entry can be variable sized, but the entire size of the queue data region (including overhead for each entry) must be specified up front.
 *
 *
In order for the IODataQueue instance to notify the user process that data is available, a notification mach port must be set.  When the queue is empty and a new entry is added, a message is sent to the specified port.
 *
 *
User client code exists in the IOKit framework that facilitates the creation of the receive notification port as well as the listen process for new data available notifications.
 *
 *
In order to make the data queue memory available to a user process, the method getMemoryDescriptor() must be used to get an IOMemoryDescriptor instance that can be mapped into a user process.  Typically, the clientMemoryForType() method on an IOUserClient instance will be used to request the IOMemoryDescriptor and then return it to be mapped into the user process.
 */
#ifndef DISABLE_DATAQUEUE_WARNING
class __attribute__((deprecated)) IODataQueue : public OSObject
#else
class IODataQueue : public OSObject
#endif
{
    OSDeclareDefaultStructors(IODataQueue)

protected:
    IODataQueueMemory *	dataQueue;

    void *		notifyMsg;

    virtual void free() APPLE_KEXT_OVERRIDE;

    /*!
     * @function sendDataAvailableNotification
     * @abstract Sends a dataAvailableNotification message to the specified mach port.
     * @discussion This method sends a message to the mach port passed to setNotificationPort().  It is used to indicate that data is available in the queue.
     */
    virtual void sendDataAvailableNotification();

public:
    /*!
     * @function withCapacity
     * @abstract Static method that creates a new IODataQueue instance with the capacity specified in the size parameter.
     * @discussion The actual size of the entire data queue memory region (to be shared into a user process) is equal to the capacity plus the IODataQueueMemory overhead.  This overhead value can be determined from the DATA_QUEUE_MEMORY_HEADER_SIZE macro in <IOKit/IODataQueueShared.h>.  The size of the data queue memory region must include space for the overhead of each IODataQueueEntry.  This entry overhead can be determined from the DATA_QUEUE_ENTRY_HEADER_SIZE macro in <IOKit/IODataQueueShared.h>.
  This method allocates a new IODataQueue instance and then calls initWithCapacity() with the given size parameter.  If the initWithCapacity() fails, the new instance is released and zero is returned.
     * @param size The size of the data queue memory region.
     * @result Returns the newly allocated IODataQueue instance.  Zero is returned on failure.
     */
    static IODataQueue *withCapacity(UInt32 size);

    /*!
     * @function withEntries
     * @abstract Static method that creates a new IODataQueue instance with the specified number of entries of the given size.
     * @discussion This method will create a new IODataQueue instance with enough capacity for numEntries of entrySize.  It does account for the IODataQueueEntry overhead for each entry.  Note that the numEntries and entrySize are simply used to determine the data region size.  They do not actually restrict the size of number of entries that can be added to the queue.
  This method allocates a new IODataQueue instance and then calls initWithEntries() with the given numEntries and entrySize parameters.  If the initWithEntries() fails, the new instance is released and zero is returned.
     * @param numEntries Number of entries to allocate space for.
     * @param entrySize Size of each entry.
     * @result Reeturns the newly allocated IODataQueue instance.  Zero is returned on failure.
     */
    static IODataQueue *withEntries(UInt32 numEntries, UInt32 entrySize);

    /*!
     * @function initWithCapacity
     * @abstract Initializes an IODataQueue instance with the capacity specified in the size parameter.
     * @discussion The actual size of the entire data queue memory region (to be shared into a user process) is equal to the capacity plus the IODataQueueMemory overhead.  This overhead value can be determined from the DATA_QUEUE_MEMORY_HEADER_SIZE macro in <IOKit/IODataQueueShared.h>.  The size of the data queue memory region must include space for the overhead of each IODataQueueEntry.  This entry overhead can be determined from the DATA_QUEUE_ENTRY_HEADER_SIZE macro in <IOKit/IODataQueueShared.h>.
     * @param size The size of the data queue memory region.
     * @result Returns true on success and false on failure.
     */
    virtual Boolean initWithCapacity(UInt32 size);

    /*!
     * @function initWithEntries
     * @abstract Initializes an IODataQueue instance with the specified number of entries of the given size.
     * @discussion This method will initialize an IODataQueue instance with enough capacity for numEntries of entrySize.  It does account for the IODataQueueEntry overhead for each entry.  Note that the numEntries and entrySize are simply used to determine the data region size.  They do not actually restrict the size of number of entries that can be added to the queue.
  This method allocates a new IODataQueue instance and then calls initWithEntries() with the given numEntries and entrySize parameters.
     * @param numEntries Number of entries to allocate space for.
     * @param entrySize Size of each entry.
     * @result Reeturns true on success and false on failure.
     */
    virtual Boolean initWithEntries(UInt32 numEntries, UInt32 entrySize);

    /*!
     * @function enqueue
     * @abstract Enqueues a new entry on the queue.
     * @discussion This method adds a new data entry of dataSize to the queue.  It sets the size parameter of the entry pointed to by the tail value and copies the memory pointed to by the data parameter in place in the queue.  Once that is done, it moves the tail to the next available location.  When attempting to add a new entry towards the end of the queue and there isn't enough space at the end, it wraps back to the beginning.
  If the queue is empty when a new entry is added, sendDataAvailableNotification() is called to send a message to the user process that data is now available.
     * @param data Pointer to the data to be added to the queue.
     * @param dataSize Size of the data pointed to by data.
     * @result Returns true on success and false on failure.  Typically failure means that the queue is full.
     */
    virtual Boolean enqueue(void *data, UInt32 dataSize);

    /*!
     * @function setNotificationPort
     * @abstract Creates a simple mach message targeting the mach port specified in port.
     * @discussion This message is sent when data is added to an empty queue.  It is to notify a user process that new data has become available.
     * @param port The mach port to target with the notification message.
     */
    virtual void setNotificationPort(mach_port_t port);

    /*!
     * @function getMemoryDescriptor
     * @abstract Returns a memory descriptor covering the IODataQueueMemory region.
     * @discussion The IOMemoryDescriptor instance returned by this method is intended to be mapped into a user process.  This is the memory region that the IODataQueueClient code operates on.
     * @result Returns a newly allocated IOMemoryDescriptor for the IODataQueueMemory region.  Returns zero on failure.
     */
    virtual IOMemoryDescriptor *getMemoryDescriptor();
};

#endif /* _IOKIT_IODATAQUEUE_H */

redpajama_set_name: RedPajamaGithub


CTG will be exhibiting at the INMEX, China Conference & Exhibition 5-7 December along with our agents Shanghai Yiwin Instrument & Equipment Co Ltd on Stand No: 1B70. Our Green Shipping Initiatives for monitoring water from Exhaust Gas Scrubber Systems & Ballast Water Treatment Systems to ensure vessels are fully compliant with global regulations will be on show.
Our team of experts have developed Sea Sentry and FastBallast to provide the shipping industry with the most accurate monitoring systems for Green Ships. CTG has built up a reputation for globally supplying ship based systems to both military and civil operators over a number of years. These systems have been installed on ferries, research vessels, yachts and tankers. We were delighted to participate in this event and pass on our sensor technology knowledge to the wider community.
CTG's agents in China - Shanghai Yiwin Instrument & Equipment Co Ltd - will be showcasing and demonstrating the Sea Sentry: Wash water monitor for exhaust gas scrubber systems and FastBallast, a portable Ballast Water Compliance Monitor.
Sea Sentry: has been certified by DNV.GL and ClassNK and is capable of monitoring both open and closed loop scrubber systems, featuring CTG's unique PAH and turbidity sensors with a de-aerator configuration. Sea Sentry monitors both the inlet and outlet of water, so that ship operators can be extremely confident that their scrubber systems are working effectively.In 2012, CTG were funded by the USCG to develop FastBallast , an active chlorophyll fluorometer test that can count algal cells as accurately as microscopy can! This ultra-sensitive device designed for monitoring Ballast Water will ultimately save time and money for ship operators, Port State Control and Flag State Agents. It is available as a marinised portable unit with a discrete sample mode and as a fully integrated solution that monitors flowing water to continually assess the efficacy of ballast water treatment systems.
CTG have been designing and manufacturing bespoke sensors and optics equipment for the aquatic environment for over 50 years. Industries we specialise in include Maritime, Marine Science, Environmental, Defence, Homeland Security and Process Control. We have built up a reputation for globally supplying ship based systems to both military and civil operators over a number of years. These systems have been installed on ferries, research vessels, yachts and tankers.
CTG's Maritime Manager, Stephanie Lavelle or our Maritime & Hydrocarbon Sales Manager Emma Johnson would be delighted to hear from you and happy to explain our green ship solutions to meet your needs.


The airport of the year was Hong Kong International Airport which, if you have ever used it, would be a popular choice. But other Asian airports dominated most of the important categories once again. Incheon Airport in Seoul, South Korea, Singapore's Changi Airport, Kuala Lumpur Airport in Malaysia and Beijing's Capital Airport all performed well. Asian airports seem to outstrip most of their British and European rivals in the quality of service and comfort that they provide.
From the UK, Heathrow won the award for Best Airport Shopping and Stansted won for Best low-Cost Airline Airport. The Sofitel in Heathrow also won Best Airport Hotel in Europe. Elsewhere British airports were also rans. Amsterdam beat both London City and Heathrow in the Best Western Europe airport category and that was about as far as any got. In the important staff service category for Europe no British airport made it into the last three, those being Dusseldorf, (which won) Zurich and Copenhagen.
One reason is that our airports are aging and new airports always seem to get more popular approval. It takes years to get through objections and planning procedures to change small things let alone build new ones. Can you remember the last time the UK had a new airport? But that is no excuse for not winning some categories such as service. Some of the worst hotels and airports I have ever passed through have been redeemed by the service I've encountered. Is our service getting worse or others performing better? Is that newer airports than ours leave a better impression on travellers so they are more likely to vote them higher in other categories rather than older and cramped ones? Take Heathrow. It is constrained by a road network making it difficult to expand without major disruption to the surrounding communities as was shown when BAA tried to persuade us that another runway was required. Now they have to redevelop in a limited area and I'm not sure the refurbished areas will ever perform as well as the completely new terminal 5 is doing.
One problem with this type of survey is that larger aiports will have larger number of voters so small airports that handle just hundreds of thousands of travelers will never have gain enough votes. So since Skytrax has introduced some new categories maybe we should have some categories broken down by the number of passengers travelling through so smaller airports can compete.
But then, would we do any better?


This a property game like Monopoly, where players roll a pencil and can spend money to buy/ open stores in a mall. Other players landing on those stores must buy at least one item from that store, and if there are none left, they have the option to buy it out. Players can expand their store by purchasing adjacent properties, and bigger stores will extra and more expensive items. Players also can use event cards to produce wild effects, making sure that no player is totally out of the game. There are several different style malls and at least eleven characters to choose from. The art style is "cute anime" and contains lots of silly humor.


text:
package org.apache.oozie;

import org.apache.oozie.client.OozieClient;
import org.apache.oozie.client.WorkflowAction;
import org.apache.oozie.client.WorkflowJob;
import org.apache.oozie.command.CommandException;
import org.apache.oozie.command.wf.ActionEndXCommand;
import org.apache.oozie.executor.jpa.WorkflowActionQueryExecutor;
import org.apache.oozie.executor.jpa.WorkflowJobQueryExecutor;
import org.apache.oozie.service.LiteWorkflowStoreService;
import org.apache.oozie.test.XDataTestCase;
import org.apache.oozie.util.XmlUtils;
import org.apache.oozie.workflow.lite.EndNodeDef;
import org.apache.oozie.workflow.lite.LiteWorkflowApp;
import org.apache.oozie.workflow.WorkflowInstance;
import org.apache.oozie.workflow.lite.LiteWorkflowInstance;
import org.apache.oozie.workflow.lite.StartNodeDef;
import org.apache.oozie.service.ELService;
import org.apache.oozie.service.Services;
import org.apache.oozie.test.XTestCase;
import org.apache.oozie.util.ELEvaluator;
import org.apache.oozie.util.XConfiguration;
import org.apache.oozie.DagELFunctions;
import org.apache.oozie.WorkflowActionBean;
import org.apache.oozie.WorkflowJobBean;

public class TestDagELFunctions extends XDataTestCase {

    protected void setUp() throws Exception {
        super.setUp();
        Services services = new Services();
        services.init();
    }

    protected void tearDown() throws Exception {
        Services.get().destroy();
        super.tearDown();
    }

    public void testFunctions() throws Exception {
        XConfiguration conf = new XConfiguration();
        conf.set(OozieClient.APP_PATH, "appPath");
        conf.set(OozieClient.USER_NAME, "user");
        conf.set("a", "A");
        LiteWorkflowApp def =
                new LiteWorkflowApp("name", "<workflow-app/>",
                    new StartNodeDef(LiteWorkflowStoreService.LiteControlNodeHandler.class, "end")).
                        addNode(new EndNodeDef("end", LiteWorkflowStoreService.LiteControlNodeHandler.class));
        LiteWorkflowInstance job = new LiteWorkflowInstance(def, conf, "wfId");

        WorkflowJobBean wf = new WorkflowJobBean();
        wf.setId(job.getId());
        wf.setAppName("name");
        wf.setAppPath("appPath");
        wf.setUser("user");
        wf.setGroup("group");
        wf.setWorkflowInstance(job);
        wf.setRun(2);
        wf.setProtoActionConf(conf.toXmlString());

        WorkflowActionBean action = new WorkflowActionBean();
        action.setId("actionId");
        action.setName("actionName");
        action.setErrorInfo("ec", "em");
        action.setData("b=B");
        action.setExternalId("ext");
        action.setTrackerUri("tracker");
        action.setExternalStatus("externalStatus");

        ELEvaluator eval = Services.get().get(ELService.class).createEvaluator("workflow");
        DagELFunctions.configureEvaluator(eval, wf, action);

        assertEquals("wfId", eval.evaluate("${wf:id()}", String.class));
        assertEquals("name", eval.evaluate("${wf:name()}", String.class));
        assertEquals("appPath", eval.evaluate("${wf:appPath()}", String.class));
        assertEquals("A", eval.evaluate("${wf:conf('a')}", String.class));
        assertEquals("A", eval.evaluate("${a}", String.class));
        assertEquals("user", eval.evaluate("${wf:user()}", String.class));
        assertEquals("group", eval.evaluate("${wf:group()}", String.class));
        assertTrue(eval.evaluate("${wf:callback('XX')}", String.class).contains("id=actionId"));
        assertTrue(eval.evaluate("${wf:callback('XX')}", String.class).contains("status=XX"));
        assertTrue(eval.evaluate("${wf:callback('XX')}", String.class).contains("status=XX"));
        assertEquals(2, (int) eval.evaluate("${wf:run()}", Integer.class));

        action.setStatus(WorkflowAction.Status.ERROR);
        System.out.println("WorkflowInstance " + wf.getWorkflowInstance().getStatus().toString());
        WorkflowInstance wfInstance = wf.getWorkflowInstance();
        DagELFunctions.setActionInfo(wfInstance, action);
        wf.setWorkflowInstance(wfInstance);

        assertEquals("actionName", eval.evaluate("${wf:lastErrorNode()}", String.class));
        assertEquals("ec", eval.evaluate("${wf:errorCode('actionName')}", String.class));
        assertEquals("em", eval.evaluate("${wf:errorMessage('actionName')}", String.class));

        assertEquals("B", eval.evaluate("${wf:actionData('actionName')['b']}", String.class));

        String expected = XmlUtils.escapeCharsForXML("{\"b\":\"B\"}");
        assertEquals(expected, eval.evaluate("${toJsonStr(wf:actionData('actionName'))}", String.class));
        expected = XmlUtils.escapeCharsForXML("b=B");
        assertTrue(eval.evaluate("${toPropertiesStr(wf:actionData('actionName'))}", String.class).contains(expected));
        conf = new XConfiguration();
        conf.set("b", "B");
        expected = XmlUtils.escapeCharsForXML(XmlUtils.prettyPrint(conf).toString());
        assertTrue(eval.evaluate("${toConfigurationStr(wf:actionData('actionName'))}", String.class).contains(expected));

        assertEquals("ext", eval.evaluate("${wf:actionExternalId('actionName')}", String.class));
        assertEquals("tracker", eval.evaluate("${wf:actionTrackerUri('actionName')}", String.class));
        assertEquals("externalStatus", eval.evaluate("${wf:actionExternalStatus('actionName')}", String.class));
    }

    // This test simulates an action that gets retried because of an Error and succeeds on one of the retries.  The lastErrorNode
    // EL function should never be set to this node.
    public void testLastErrorNodeWithRetrySucceed() throws Exception {
        WorkflowJobBean job = this.addRecordToWfJobTable(WorkflowJob.Status.RUNNING, WorkflowInstance.Status.RUNNING);
        WorkflowActionBean action = this.addRecordToWfActionTable(job.getId(), "1", WorkflowAction.Status.END_RETRY, true);
        action.setType("java");
        action.setExternalStatus("FAILED");
        action.setErrorInfo("JA018", "some error occurred");
        WorkflowActionQueryExecutor.getInstance().executeUpdate(
                WorkflowActionQueryExecutor.WorkflowActionQuery.UPDATE_ACTION, action);

        new ActionEndXCommandIgnoreSignalException(action.getId(), action.getType()).call();

        ELEvaluator eval = Services.get().get(ELService.class).createEvaluator("workflow");
        job = WorkflowJobQueryExecutor.getInstance().get(WorkflowJobQueryExecutor.WorkflowJobQuery.GET_WORKFLOW, job.getId());
        action = WorkflowActionQueryExecutor.getInstance().get(
                WorkflowActionQueryExecutor.WorkflowActionQuery.GET_ACTION, action.getId());
        DagELFunctions.configureEvaluator(eval, job, action);
        assertEquals("", eval.evaluate("${wf:lastErrorNode()}", String.class));

        action.setExternalStatus("SUCCEEDED");
        action.setStatus(WorkflowAction.Status.DONE);
        WorkflowActionQueryExecutor.getInstance().executeUpdate(
                WorkflowActionQueryExecutor.WorkflowActionQuery.UPDATE_ACTION, action);

        new ActionEndXCommandIgnoreSignalException(action.getId(), action.getType()).call();

        job = WorkflowJobQueryExecutor.getInstance().get(WorkflowJobQueryExecutor.WorkflowJobQuery.GET_WORKFLOW, job.getId());
        action = WorkflowActionQueryExecutor.getInstance().get(
                WorkflowActionQueryExecutor.WorkflowActionQuery.GET_ACTION, action.getId());
        assertEquals(WorkflowAction.Status.OK, action.getStatus());
        DagELFunctions.configureEvaluator(eval, job, action);
        assertEquals("", eval.evaluate("${wf:lastErrorNode()}", String.class));
    }

    // This test simulates an action that gets retried because of an Error and never succeeds on later retries.  The lastErrorNode
    // EL function should be set to this node, but only after the last retry.
    public void testLastErrorNodeWithRetryFail() throws Exception {
        WorkflowJobBean job = this.addRecordToWfJobTable(WorkflowJob.Status.RUNNING, WorkflowInstance.Status.RUNNING);
        WorkflowActionBean action = this.addRecordToWfActionTable(job.getId(), "1", WorkflowAction.Status.END_RETRY, true);
        action.setType("java");
        action.setExternalStatus("FAILED");
        action.setErrorInfo("JA018", "some error occurred");
        WorkflowActionQueryExecutor.getInstance().executeUpdate(
                WorkflowActionQueryExecutor.WorkflowActionQuery.UPDATE_ACTION, action);

        new ActionEndXCommandIgnoreSignalException(action.getId(), action.getType()).call();

        ELEvaluator eval = Services.get().get(ELService.class).createEvaluator("workflow");
        job = WorkflowJobQueryExecutor.getInstance().get(WorkflowJobQueryExecutor.WorkflowJobQuery.GET_WORKFLOW, job.getId());
        action = WorkflowActionQueryExecutor.getInstance().get(
                WorkflowActionQueryExecutor.WorkflowActionQuery.GET_ACTION, action.getId());
        DagELFunctions.configureEvaluator(eval, job, action);
        assertEquals("", eval.evaluate("${wf:lastErrorNode()}", String.class));

        action.setExternalStatus("FAILED");
        action.setErrorInfo("JA018", "some error occurred");
        action.setStatus(WorkflowAction.Status.END_RETRY);
        action.setUserRetryCount(action.getUserRetryMax()); // make it the last retry
        WorkflowActionQueryExecutor.getInstance().executeUpdate(
                WorkflowActionQueryExecutor.WorkflowActionQuery.UPDATE_ACTION, action);

        new ActionEndXCommandIgnoreSignalException(action.getId(), action.getType()).call();

        job = WorkflowJobQueryExecutor.getInstance().get(WorkflowJobQueryExecutor.WorkflowJobQuery.GET_WORKFLOW, job.getId());
        action = WorkflowActionQueryExecutor.getInstance().get(
                WorkflowActionQueryExecutor.WorkflowActionQuery.GET_ACTION, action.getId());
        assertEquals(WorkflowAction.Status.ERROR, action.getStatus());
        DagELFunctions.configureEvaluator(eval, job, action);
        assertEquals(action.getName(), eval.evaluate("${wf:lastErrorNode()}", String.class));
    }

    private class ActionEndXCommandIgnoreSignalException extends ActionEndXCommand {

        public ActionEndXCommandIgnoreSignalException(String actionId, String type) {
            super(actionId, type);
        }

        @Override
        protected Void execute() throws CommandException {
            try {
                return super.execute();
            } catch (CommandException ce) {
                // ActionEndXCommand will trigger a SignalXComamnd, which will complain about executionPath being empty -- ignore it
                if (!(ce.getCause() instanceof IllegalArgumentException)
                        || !ce.getMessage().equals("E0607: Other error in operation [signal], executionPath cannot be empty")) {
                    throw ce;
                }
            }
            return null;
        }
    }
}


text:
A Conversation with the Investigators: Endometrial and Cervical Cancers (Faculty Presentations)
Released September 2021
Featuring slide presentations and related discussion from Drs Mansoor Raza Mirza, David O'Malley and Angeles Alvarez Secord. Published September 9, 2021. (Faculty Presentations)
This program is intended for medical oncologists, hematology-oncology fellows and other allied healthcare professionals involved in the treatment of gynecologic cancers.
Review available data with anti-PD-1/PD-L1 antibodies for patients with microsatellite instability (MSI)-high and microsatellite-stable recurrent endometrial cancer, and appreciate ongoing research attempting to define the role of these agents in the treatment of this disease.
Consider the FDA approval of pembrolizumab in combination with lenvatinib for patients with advanced endometrial cancer that is not MSI high or mismatch repair deficient (dMMR) who have experienced disease progression after systemic therapy, in order to optimally integrate this novel regimen into clinical management algorithms.
Recognize the recent FDA approval of dostarlimab for patients with dMMR advanced endometrial cancer after disease progression on or after a prior platinum-based regimen.
Appraise available and emerging research findings supporting the use of immune checkpoint inhibitors for progressive advanced cervical cancer, and identify patients appropriate for treatment with these agents in or outside of a clinical research study.
Consider emerging pivotal research findings with and the potential clinical role of tisotumab vedotin in therapy for recurrent cervical cancer.
Design and implement a plan of care to recognize and manage side effects and toxicities associated with immune checkpoint inhibitors in the management of endometrial and cervical cancer in order to support quality of life and continuation of therapy.
Recall the design of ongoing clinical trials evaluating novel agents and strategies for patients with endometrial and cervical cancer, and counsel appropriate individuals about availability and participation.
Research To Practice designates this enduring material for a maximum of 2 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 2 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Please note, this program has been specifically designed for the following ABIM specialty: medical oncology.
This CME activity consists of a video component. To receive credit, the participant should review the CME information, watch the video, complete the Post-test with a score of 80% or better and fill out the Educational Assessment and Credit Form located at ResearchToPractice.com/ASCOEndoCervical21/Presentations/CME.
Research To Practice (RTP) is committed to providing its participants with high-quality, unbiased and state-of-the-art education and adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of an accredited continuing education activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of this activity. In addition, all activity content is reviewed by RTP scientific staff and an external, independent physician reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.
FACULTY — The following faculty reported relevant financial relationships with ineligible entities:
Mansoor Raza Mirza, MD
Nordic Society of Gynaecological Oncology – Clinical Trial Unit
Chairman, European Network of Gynaecological Trial Groups
Faculty Member, European Society of Gynaecological Oncology
Chief Oncologist
Copenhagen University Hospital
Advisory Committee: Karyopharm Therapeutics, Sera Prognostics; Global Clinical Lead: ENGOT-OV16/NOVA niraparib, ENGOT-EN6/NSGO-RUBY; Institutional Financial Interests (Study Grants): AstraZeneca Pharmaceuticals LP, Boehringer Ingelheim Pharmaceuticals Inc, Clovis Oncology, Pfizer Inc, Tesaro, A GSK Company, Ultimovacs; Personal Financial Interests: AstraZeneca Pharmaceuticals LP, BIOCAD, Clovis Oncology, Geneos Therapeutics, Genmab, Karyopharm Therapeutics, Merck, Merck Sharp & Dohme Corp, Mersana Therapeutics, Oncology Venture, Pfizer Inc, Roche Laboratories Inc, Seagen Inc, Sera Prognostics, SOTIO LLC, Takeda Oncology, Tesaro, A GSK Company, Zai Lab.
David M O'Malley, MD
Division Director, Gynecologic Oncology
Co-Director, Gynecologic Oncology Phase I Program
The Ohio State University and The James Cancer Center
Advisory Committee and Consulting Agreements (Personal Fees): AbbVie Inc, Agenus Inc, Ambry Genetics, Amgen Inc, AstraZeneca Pharmaceuticals LP, Clovis Oncology, Eisai Inc, Elevar Therapeutics, Genentech, a member of the Roche Group, GOG Foundation Inc, ImmunoGen Inc, Iovance Biotherapeutics, Janssen Biotech Inc, Johnson & Johnson Pharmaceuticals, Merck, Mersana Therapeutics, Myriad Genetic Laboratories Inc, Novartis, Novocure Inc, Regeneron Pharmaceuticals Inc, Rubis, Seagen Inc, Tarveda Therapeutics, Tesaro, A GSK Company; Contracted Research (All Funding to Institution): AbbVie Inc, Agenus Inc, Ajinomoto Co Inc, Amgen Inc, Array BioPharma Inc, a subsidiary of Pfizer Inc, AstraZeneca Pharmaceuticals LP, Bristol-Myers Squibb Company, Daré Bioscience, Eisai Inc, EMD Serono Inc, Ergomed Plc, Genentech, a member of the Roche Group, Genmab, GOG Foundation Inc, ImmunoGen Inc, Iovance Biotherapeutics, Janssen Biotech Inc, Johnson & Johnson Pharmaceuticals, Ludwig Institute for Cancer Research Ltd, Merck, National Cancer Institute, New Mexico Cancer Care Alliance, Novocure Inc, PRA Health Sciences, Regeneron Pharmaceuticals Inc, Seagen Inc, Stemcentrx, Syneos Health, Tesaro, A GSK Company, TRACON Pharmaceuticals Inc, VentiRx Pharmaceuticals Inc, Yale University; Contracted Research (Personal Fees): Clovis Oncology, Mersana Therapeutics; Data and Safety Monitoring Board/Committee: Watermark Research Partners Inc.
Angeles Alvarez Secord, MD, MHSc
Professor of Obstetrics and Gynecologist, Gynecologic Oncology
Director of Gynecologic Oncology Clinical Trials
Duke Cancer Institute
Advisory Committee (Honorarium): Myriad Genetic Laboratories Inc; Advisory Committee (Uncompensated): AbbVie Inc, AstraZeneca Pharmaceuticals LP, Clovis Oncology, Regeneron Pharmaceuticals Inc, Tesaro, A GSK Company; Contracted Research: AbbVie Inc, AstraZeneca Pharmaceuticals LP, Boehringer Ingelheim Pharmaceuticals Inc, Clovis Oncology, Eisai Inc, Genentech, a member of the Roche Group, Merck, Seagen Inc, Tesaro, A GSK Company; Clinical Trial Steering Committee (Uncompensated): F Hoffmann-La Roche Ltd and Genentech, a member of the Roche Group, for the AtTEnd trial.
MODERATOR — Dr Love is president and CEO of Research To Practice. Research To Practice receives funds in the form of educational grants to develop CME activities from the following companies: AbbVie Inc, Adaptive Biotechnologies Corporation, ADC Therapeutics, Agios Pharmaceuticals Inc, Alexion Pharmaceuticals, Amgen Inc, Array BioPharma Inc, a subsidiary of Pfizer Inc, Astellas, AstraZeneca Pharmaceuticals LP, Aveo Pharmaceuticals, Bayer HealthCare Pharmaceuticals, BeiGene Ltd, Blueprint Medicines, Boehringer Ingelheim Pharmaceuticals Inc, Bristol-Myers Squibb Company, Celgene Corporation, Clovis Oncology, Coherus BioSciences, Daiichi Sankyo Inc, Eisai Inc, Epizyme Inc, Exact Sciences Inc, Exelixis Inc, Five Prime Therapeutics Inc, Foundation Medicine, Genentech, a member of the Roche Group, Gilead Sciences Inc, GlaxoSmithKline, Grail Inc, Halozyme Inc, Helsinn Healthcare SA, ImmunoGen Inc, Incyte Corporation, Ipsen Biopharmaceuticals Inc, Janssen Biotech Inc, administered by Janssen Scientific Affairs LLC, Jazz Pharmaceuticals Inc, Karyopharm Therapeutics, Kite, A Gilead Company, Lilly, Loxo Oncology Inc, a wholly owned subsidiary of Eli Lilly & Company, Merck, Novartis, Novocure Inc, Oncopeptides, Pfizer Inc, Pharmacyclics LLC, an AbbVie Company, Puma Biotechnology Inc, Regeneron Pharmaceuticals Inc, Sanofi Genzyme, Seagen Inc, Sumitomo Dainippon Pharma Oncology Inc, Taiho Oncology Inc, Takeda Oncology, Tesaro, A GSK Company, TG Therapeutics Inc, Turning Point Therapeutics Inc and Verastem Inc.
This activity is supported by educational grants from AstraZeneca Pharmaceuticals LP, Clovis Oncology, Eisai Inc, GlaxoSmithKline, ImmunoGen Inc and Merck.
Release date: September 2021
Expiration date: September 2022
Contemporary Biomarker Assessment in Advanced Endometrial Cancer and Cervical Cancer — Mansoor Raza Mirza, MD
Current Treatment Planning for Patients with Advanced Endometrial Cancer — David M O'Malley, MD
Selection of Therapy for Patients with Advanced Cervical Cancer — Angeles Alvarez Secord, MD, MHSc


We meet at Steve's Pizza, located at 314 F Street, in Davis, CA, on Thursdays from 6 p.m. until closing. We also meet in Sacramento at Market Square in Arden Fair Sacramento from 6:00-10 pm. Exit business I-80 east, and look on your left (drive carefully!) for "Market Square" located between "United Artists Theater" and "Barnes & Noble." There are ongoing experiments with meeting at different places on different dates, so check the above web site to see what might work best for you.
We play four tournaments a year, usually at the Arcade Library, 2443 Marconi Ave. Sacramento.
The club has been active since at least 1995. The majority of players are between 1 and 7 kyu, though both high-kyu and dan-level players are represented. Beginners/interested non-players are most welcome; a few are usually being taught at any time. Recent tournaments have drawn as many as 24 players, both members and non-members. While the university (UC Davis) has brought many players to the club, the club does not have any affiliation with the university, and is not a student organization.
The low overhead for Go playing space (pizza slices at Steve's and a variety of items at Market Square) has allowed dues to remain relatively low. Most of the dues go to covering the costs of space for tournaments. These costs are considerably higher in most metropolitan areas with Go clubs. One goal of this club is to promote the enjoyment of a fascinating game without unduly draining your wallet.


Great customer experience drives long-term value, and technology is one of the key elements required to achieve the same. However, in spite of the presence of several competing technologies, enterprises often stumble in choosing the most effective solution that augurs well with their business processes and needs. Addressing to the industries' concerns, Joseph Vu, Director, SimByte, a provider of Microsoft's Dynamics CRM and Mobile Technology quips, "Potential clients often complained that IT companies are only interested in selling them the 'proven system' which did not always meet their requirements." Founded in 2008, SimByte is one such organization that is familiar with the tricks of the trade and delivers long-term benefits to clients by deploying Microsoft Dynamics Sure Step CRM software.
Joseph, a seasoned professional, knows very well that a frictionless customer experience is the key to the successes of a business, and this can be attained only through the deployment of an effective CRM (Customer, Relationship, and Management) software. This CRM Software facilitates enterprises to effortlessly access their business information, manage customer data & customer interactions, automates sales & marketing, and facilitates collaboration among employees, vendors, as well as partners. Headquartered in North Sydney, Australia, SimByte provides Custom solutions, Brand solutions and, SharePoint and Exchange Services. The Company has strong foothold across the country, which vindicates from its branch office located in Melbourne, Victoria, Australia.
Avacent is one of SimByte's flagship products that offers e-learning, business audit, staff performance management, customer survey services and a unique online Resource Library. An iphone product will be available shortly providing greater options for business and staff. Its compliance and management system is perfectly suitable for small to very large business, with the largest client having over 10,000 users.
Besides, SimByte's another product has been specifically designed for the Telecommunications sector with Ordering & Invoicing, SIM management, inventory and Voice, data and SMS rating. Additionally, this product also supports customer portal component that facilitates customers to view their bills, usage and lodge complains online.
Based on CRM Dynamics, the Company's new product-Affinity, is supposed to be released into the market with customer and membership management, event management, ticketing, purchasing and seating plan allocation. Affinity is suitable for any business that sells products to customers based around an event product and can be scaled from small functions to large-scale events.
Simbyte is also proficient in providing SSIS & SSRS set of solutions which are extensively used for reporting solutions, integration, and data transformation process.
Additionally, the company has certified staff, which renders SharePoint & Exchange services to slew of its clients. Besides, SimByte also provides a host of mobile technology to its customers' which include HTML5 compliant applications, Geo-fencing applications, Ticket and barcode readers, innovative sign recognition application and bespoke portal applications. These Mobile Technologies have so far immensely fortified their client's processes and helped them to grow leaps and bounds over a span of few years.
The company's competent technical staffs are the organization's biggest asset. By adopting a flexible approach and applying a pragmatic and honest approach in scope and project management, the Company's dynamic resources meets the current and future requirements of the clients. These vibrant resources serve as subject matter experts for diversified sectors such as Pharmaceuticals, Not-for-Profit, Entertainment, Government, and Telecommunications. Some of the elite clients of SimByte include Victoria Racing Club, Racing Victoria, Compass Group Catering, Rydges Hotels, Vodafone, Mantra, HT Solutions and the Royal Commission into Child Sexual Abuse.
Simbyte's utmost dedication in delivering true customer satisfaction has earned the Enterprise plethora of prestigious awards such as Microsoft Partner Network in 2010, a vmware partner award in 2011, Qassure Accredited Business award in 2013, certified PCEHR Integration provider award in 2014 and SimByte Completion for High Performance Data Center among many others. Going forward, the company is planning to build its own membership and events management functionality within Dynamics CRM, a native iPad app for access to Dynamics entities and a mobile responsive Dynamics customer portal to upload documents directly into CRM. "We plan to take our mobile applications to the next level and the future will see us bringing secure and innovative pharmaceutical applications to the mobile platform," saying so Joseph signs off.


Situated in the southern section of the Nambiti Private Game Reserve in KwaZulu Natal, Cheetah Ridge Luxury Safari Lodge is an unrivalled bush retreat, offering fully-catered, accommodation in 10 luxury suites, as well as a sumptuously-appointed family suite which sleeps up to six people.
Overlooking a private watering-hole, each free-standing suite allows guests the opportunity to observe a vast array of congregating African wildlife from the privacy of their personal viewing deck.
Whether you're enjoying al fresco dining under the stars beneath an 111-year-old Natal Fig tree, experiencing a private bush dinner in a secluded corner of the reserve, or indulging in a rejuvenating spa treatment at our on-site spa, Cheetah Ridge Lodge is the ultimate "must visit" safari destination.
Cheetah Ridge has a homely and inviting atmosphere, ensuring that guests are welcomed to a home away from home. The family suite is the perfect option for families with children who would still like the option of being fully catered for. The suite comes complete with air-conditioning and Nespresso machine in each room. The suite is set within the main lodge and consists of 2 rooms joined by a private lounge with a private balcony overlooking the beautiful Nambiti Game Reserve. The family suite sleeps a maximum of 6 guests with one room having a 4 pillar king size bed and the adjacent room can either have a king bed and 2 singles combination or simply 4 single beds. Each room also has their own en suite bathroom.
Situated away from the lodge, our 10 king luxury suites overlooks a private watering-hole, enabling guests to observe a vast array of African wildlife from the privacy of their personal viewing deck. Serviced daily and sumptuously decorated, each free-standing suite is equipped with a bath, shower, and en-suite toilet, with a pod-hanging chair to take in the unfolding majesty of the scenes before you. Air-conditioning and ceiling fans for balmy summer evenings, with a Bosca Fireplace and Nespresso coffee machine for chilly nights, complete the picture to ensure a luxurious, yet homely, stay.
Nestled in the grounds of Cheetah Ridge Lodge, Nambiti House is the only exclusive use lodge in the Nambiti Private Game Reserve to offer a Big 5 game drive experience. Ideal for families and groups, Nambiti House provides a secluded family-friendly environment, with access to the Main Lodge facilities on request. Set in its own fenced-off garden complete with plunge pool, Nambiti House offers a homely family getaway destination that can comfortably accommodate 10 people in five spacious bedrooms - the largest of which has its own en-suite bathroom.


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TH 311 - Church History I: Early and Medieval Catholicism
The course is the first of a two-part survey of the evolution of the Catholic Church from Apostolic times to the present. Although concerned primarily with the story of the Catholic West, Church History I includes the history of the Orthodox East and the gradual separation of the Latin and Greek Churches in the course of the Middle Ages.
Assignment Overview
Assignments: 6 Units
Interactivity: Discussion Board
Upon completion of this course, you should be able to do the following:
Explore the way Church structures, especially the papacy and the episcopacy, evolved in the first millennium as well as more of the Church's history.
Identify some of the ways (political, social, and educational) in which the Church responded to the declining Roman Empire in the West.
Appreciate the role of monasticism, beginning with the desert fathers and culminating in the new mendicant orders of the Middle Ages, including its missionary activities.
Understand the cultural and theological background to the East-West Schism.
Recognize the difference between a patristic/monastic style of theology and the scholastic style that emerged in the twelfth century.
Use historical examples to illustrate the social and embodied nature of the Spirit-led Church as it extends the Incarnation of Christ in the world.
Evaluate and consult online reference and primary source materials that provide details of topics in Church history that go beyond the introductory level.