Jing Chen, PhD, of Boston Children's Hospital, Harvard, is looking for the culprit that causes leaky blood vessels to grow uncontrollably near the retina in wet age-related macular degeneration (AMD), which can lead to vision loss.
She thinks it may stem from signaling by small regulatory RNAs, known as "microRNAs" (miRNAs). RNA (ribonucleic acid) translates our genetic blueprint for our cells to know how to take action. miRNAs are short-term fixes to these gene blueprint translations that either help or harm our bodies as they adjust to changing conditions and stressors.
Stressors that may lead to wet AMD include inflammation, lipid and nutrient imbalances, cumulative environmental wear and tear, and reduced cell maintenance functions due to age and/or lifestyle factors. Dr. Chen believes these conditions may bring about harmful miRNA signaling, which in turn may trigger AMD.
She and her colleagues have identified a strong miRNA candidate for errant blood vessel growth, miR-145. Their experiments showed that in a mouse model of AMD, miR-145 levels more than doubled compared with normal controls. When they injected an miR-145 inhibitor, new blood vessel growth was cut in half. Similarly, human cell cultures showed greatly reduced blood vessel growth once miR-145 was inhibited.
This approach has not yet been through clinical trials, but the results strongly suggest that inhibiting miR-145 could help stop abnormal blood vessel growth in wet AMD. Thanks to findings made possible by her Macular Degeneration Research grant, Dr. Chen has now received funding from the National Eye Institute to carry this promising work forward.
I'm excited about the progress we're making against AMD! As our cover story shows, a researcher we fund has identified a culprit that may trigger abnormal blood vessel growth in the eye. This important discovery could ultimately save the sight of millions of Americans who are at risk of irreversible vision loss from wet AMD.
I'm also delighted by the symposium that BrightFocus Foundation spearheaded recently at the world's largest meeting of vision researchers. Scientists discussed research showing how diet, vitamins, and other lifestyle factors can impact the development of AMD. This gives hope to people living with this disease.
Your generosity makes all our sight-saving work possible. With your ongoing support, we will continue to tackle AMD on multiple fronts until one day we have a cure.
What does scientific research show about the impact of vitamins, lifestyle, and diet on the development of AMD?
That was the topic of a recent innovative symposium at the annual meeting of the Association of Research in Vision and Ophthalmology, the world's largest group of vision scientists. It was the brainchild of BrightFocus Foundation, of which Macular Degeneration Research is a program.
More than 200 scientists heard from experts like Emily Chew, MD, of the National Eye Institute (NEI), who helped lead the landmark Age-Related Eye Disease Studies (AREDS I and II). This led to the AREDS "eye vitamin" regimen for early-to-moderate AMD.
She addressed the interaction between diet and genetics in AMD. Several dozen genes have been linked to an increased risk for AMD. One study assessed AREDS in combination with a modified Mediterranean diet high in vegetables, fruits, and fish, and low in processed meats, alcohol, and saturated fats.
While overall this diet was linked to a lower risk for advanced AMD, results for genetically susceptible individuals weren't conclusive. Dr. Chew is designing additional NEI research in this area.
Louis Pasquale, MD, of Harvard, stressed that "genetics is not destiny" in AMD. Although there is a genetic link, he speculates that it could be modified by lifestyle factors—much like obesity, which is linked to genes but can be managed through diet and exercise. Future discoveries may furnish "powerful insights into ophthalmic disease and can lead to cost-effective primary prevention measures," he said.
Julie Mares, PhD, of the University of Wisconsin-Madison, has led large, long-term studies assessing the impact of diet on AMD. As she discussed, scientists believe that vitamins C and E, carotenoids like lutein and zeaxanthin, and zinc help protect the retina against oxidative damage from stressors such as lifelong light exposure, changes in energy metabolism, inflammation, and reduced cell waste removal functions.
In a recent BrightFocus Chat, Priyatham Mettu, MD, a retina specialist at Duke University, answered callers' questions.
Q: How can patients make the most out of their doctor's appointment?
A: Many patients are referred to a retina specialist by another doctor. Bring in- hand any records of prior evaluations, imaging, or treatment. That helps the doctor give an informed opinion about what's best for you. Also, write down questions in advance so you remember to ask them. If at the end of your visit you didn't fully understand anything, say, "Here's what I wasn't sure about: Could you tell me more about this, could you give me more information about that?" That way, when you leave, you feel comfortable with what you've learned.
Q: What are long-term side effects of eye injections for wet AMD?
A: For most patients, the current anti-vascular endothelial growth factor (anti- VEGF) treatments are safe. All the available data for those who have been treated for 7 to 10 years suggests patients can receive these injections with very few ill side effects.
Q: What is the right frequency for shots?
A: We typically inject once a month for three months and then re-evaluate. If there's no sign that the blood vessel is getting bigger or bleeding, we can gradually extend the interval between shots. If not, we have to consider switching to another anti-VEGF treatment or adding other therapies, such as laser treatments.
Q: Is there any new research that would eliminate eye injections?
A: I think on the horizon there are going to be a host of new treatments around extended-release treatments. Instead of coming once a month, you might come once every six months.
Q: How can I take part in a clinical trial?
A: Ask your eye doctor what stage of AMD you are in, what you can expect going forward, and if he or she is aware of any clinical trials. Your doctor should be able to highlight potential trials and if you might be a good candidate for them.
Leona and her daughter, Sharon, were guest speakers at a recent BrightFocus Chat.
When Leona was first diagnosed with AMD, she didn't notice any difference in her vision. She continued teaching, driving, and living her normal life.
But after retiring, Leona realized she needed more help. She moved closer to her eldest daughter, Sharon.
"It was a while before I realized how important it was to attend doctor appointments with her," says Sharon. Now she would advise other caregivers to attend every doctor's visit, take notes, and ask questions that the patient may forget to ask. Also, counseling can help, since there is a risk for depression for the patient as well as the caregiver who is suddenly thrust into a new role.
Unfortunately, when Leona's AMD changed from dry to wet, she didn't realize she was having a bleed. "I didn't get to my eye doctor right away, thinking that the graying of my vision was from cataracts. By the time I got [there], I had lost more vision. Who knows, but it might have been prevented. So, even if you don't want to be one of those patients who calls with every symptom, I encourage you to be one," she says.
Leona has also remained independent at home, thanks to technology like magnifiers, computers, reading machines, and labels on appliances.
Recently diagnosed with AMD? Know someone who has it? Receive helpful information from our FREE monthly phone call with doctors, researchers, or experts in the field on timely topics. You can submit questions before or during the event. Transcripts and audio recordings are available afterward on our website.
To register, call 800-437-2423 or go to brightfocus.org/eyechats.
As part of our ongoing series of articles about clinical trials, we will look at the three phases of clinical trials. Each has a specific purpose in determining the safety and efficacy of a treatment for use by the public.
Phase 1 Clinical Trials evaluate the safety of a drug or treatment to determine that it is not harmful to people. This testing normally takes place with a small group of healthy volunteers, and negative effects may lead the Food and Drug Administration (FDA) to discontinue the trial.
Phase 2 Clinical Trials test the right dosage and effectiveness in treating a disease. A small group of volunteers who have the disease are assigned to different treatment groups, with each group receiving different doses. The results are then compared to control groups (trial participants who did not receive treatment). If the results show either adverse outcomes or no improvement, the trial can either be suspended or discontinued.
Phase 3 Clinical Trials test whether a treatment is safe and effective for a wide variety of people. With a larger number of volunteers, there can be many groups, especially if the treatment involves a combination of drugs or different components. Again, the results are compared to control groups. If the drug works and the trial is successful, the trial sponsor may now apply to the FDA for approval to manufacture and sell these new treatments, making them available to patients.
Today's clinical trials can lead to better treatments tomorrow. For more information about clinical trials or to find one near you that you may be able to participate in, please visit brightfocus.org/AMDtrials.
This series of articles promoting awareness of clinical trials is supported in part by an educational sponsorship from Biogen. BrightFocus is solely responsible for the content of this article.
People often want to make a philanthropic gift but feel they can't afford it. Here are two common obstacles we hear… and some solutions.
Solution: You can support our future work by remembering us in your will or living trust. It's simple to do and you can change your mind at any time.
Solution: Rather than making a gift of cash now, consider the options below, which can offer important tax savings for you and your family.
Stock. For gifts of appreciated stock owned longer than one year, you receive an income tax charitable deduction for their full fair market value—not the price you originally paid for them.
Life insurance. You can name our organization as the beneficiary of a policy you no longer need.
Retirement plan assets. Highly taxed when left to heirs, this makes an excellent charitable gift after your lifetime.
Macular Degeneration Research News is published by Macular Degeneration Research, a program of BrightFocus Foundation. This information should not in any way substitute for the advice of a qualified health care professional. BrightFocus Foundation does not endorse any medical product or therapy.


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"disabled in" or "disabled for"?
Prepositions after "disabled"
Is it usefull? ★★★★☆ (3.5 / 2 votes)
In 24% of cases disabled in is used
I an disabled in that language.
There are jobs for the disabled in India.
Census tried to count the disabled in 1981.
Q: I wanted to make a career in the film industry but I am disabled in my left hand.
HEALTHCARE At a demonstration by the disabled in central Athens, tempers were rising.
To try to solve this problem the ICRC began the Special Fund for the Disabled in 1983.
But I CAN make home visits to the elderly and disabled in my village, which I am really looking forward to starting.
Judging from the above, the legal rights of the disabled in the Shanghai children's welfare home are well protected.
In September 1994 the Chinese government held the Sixth Far East and South Pacific Games for the Disabled in Beijing.
In 17% of cases disabled for is used
Race control is disabled for first season.
Almost like using the disabled for entertainment.
Autofocus is disabled for most third-party lenses.
I have multiple health problems &; have been registered as disabled for several years.
This will keep him disabled for a couple seconds while you take out any goons he doesn't hit.
She developed pneumonia and polio as a child, rendering her disabled for most of her childhood.
The rest of us? We have a government punishing the poor, the sick and the disabled for the crimes of the wealthy.
Autofocus is known to be disabled for lenses shown in italic, and may be disabled for the other lenses shown below.
Moreover, Paul Konerko had a concussion and went on the disabled for the first time since 2008 (more on that later).
Bottom link: =: Disabled for all Display WAP1/WAP2 switch link in: =:: This would remove that: =: link from your site.
In 9% of cases disabled by is used
Withings is disabled by default.
David, I am disabled by brain injury.
I feel like I've lost an arm: I'd disabled by her absence.
Secondly the zoom function can be enabled and disabled by pressing Command-Option-8.
Anti-aliasing is disabled by default for GDI+ and AWT, and enabled by default for WPF.
Most of those driven over were killed or disabled by the fall, and only a few got away.
I am Disabled by society's unwillingness to include me as a full member of society because of those medical conditions.
The human predicament is that the will has been corrupted and disabled by sin to respond to the revelation of God by faith.
GETTING IN AND OUT OF A SHOWER The following specifications are recommended in Designing for the Disabled by Selwyn Goldsmith.
In 5% of cases disabled with is used
I am sick and disabled with no income.
I am disabled with MS, and am legally blind.
My sister has become disabled with a Pettah bomb.
No doubt the Paralympics will be used as a tool to beat the non-working disabled with.
If the cane lessens your pain, you will not be as disabled with one as you would be without on.
I'd disabled with a brain malformation and the Herb helps significantly improve my quality of life every day.
Other places worth for visiting is Neema crafts centre for the disabled with an excellent cafe and tours of their workshops available.
When the war ended, thousands of ex-servicemen, many disabled with physical or emotional wounds, had to be re-integrated into a society keen.
Features: Disabled have lower income because of imperfection at work and they can avail easy finance from loans for disabled with several benefits.
That kind of cash could easily feed the more than one hundred kids at the Kiribati School for the Disabled with one warm meal a day for more than a year.
In 5% of cases disabled as is used
I got something anyone can get, and its left me disabled as a result.
Nor would it help dependent caretakers, or people who are disabled as a result of choices they made.
If the member is incapacitated or disabled as a result of his/her employment/in the cause of his/her employment.
Yet every day at least 144 employed people are left disabled as a result of serious illness or accidental injury.
He has in interest in advocacy for the rights of the disabled as well as ensuring positive outcomes for the aged.
Objective standards do not insultingly represent the disabled as deserving aid because of their pitiful internal condition.
You don't need to put I AM DISABLED as the first line on your CV -- trust me, I tried, I thought it would appeal to the BBC.
As our population ages, we will get more ill and more disabled as a population, just as our older population will be getting poorer.
Equality of fortune, despite the fact that it considers the treatment of the disabled as a core case, has difficulty with such ideas.
In May 2006, our Lions Club decided to buy a purpose built, 6 Berth, Mobile Home which caters for holidays for the Disabled as well as families.
In 5% of cases disabled at is used
Disabled at the age of 51 I wasn't happy.
Anyone of us could become disabled at any time.
It does, however, get disabled at times you may need it.
There is a pedestrian entrance and access for the disabled at the top of Henrietta Street.
The sick and disabled at this time are extremely stressed by all of these welfare reforms.
In general people with HD become very disabled at about 10-15 years from the onset of symptoms.
Let those goofballs take a pay cut and then we will talk fiscal equality! Disabled at the age of 51 I wasn't happy.
I work now in Sheffield as a carer with people with learning difficulties and disabled at a day centre in Pittsmoor.
Not only does this put the sick or disabled at risk, it also downgrades their status as human beings while they are alive.
He was addressing the fifth anniversary celebration of the district branch of the Federation of the Disabled at Mamponteng.
In 5% of cases disabled from is used
Disabled from RA but still play when I can.
A law that excludes the disabled from protection is such a law.
Google AdSense Alternatives If you were disabled from the program.
Pleshakova, 26, a disabled from childhood, will forever remember her day on 6 August.
Disabled from birth, Mike has been fighting for his rights since he was in grade school.
This Automatic Vowel Forming can also be kept disabled from the Configuration dialog box.
Long-term disability (LTD) insurance is designed to provide replacement income should you become disabled from work.
Individual power commands can be enabled or disabled from the Power Commands page in Tools -> Options in Visual Studio.
The current law exists to protect those who are sick, elderly, depressed or disabled from feeling obliged to end their lives.
Orthodox Christian Natalya Pleshakova who is disabled from childhood and her mother have been severely beaten up and tried in Tashkent.
In 4% of cases disabled to is used
We are all disabled to varying disagrees.
People who are too disabled to work can get benefits for life.
But this had to return disabled to England without touching land.
Disability policies should ensure the access of the disabled to all community services.
Those found too sick or disabled to work won't be expected to and will continue to receive the help and support they need.
What's worse is, I feel furtive and guilty because I know I do not look disabled to others and I hate that even if I cant control it.
But, I've spent a lot of time teaching all kinds of people, from the disabled to the gifted and I'd effective because people like me.
It's almost a truism that staff generally have more behavioural problems than clients and, in that respect, we are all disabled to some degree.
It is also critical to provide access for wheel chairs and motorized scooters for the handicapped and disabled to the picnic tables and benches.
This book is valuable for educators and parents who work with students, from learning disabled to those who are not what we would classify as learning disabled.
In 4% of cases disabled on is used
Labour Standards now provide for those who become disabled on the job.
Accommodating the disabled on campus or travel The accommodation is accessible.
Another bus has become disabled on route 3 and ours was going to pick up the stranded passengers.
Hari Raya open house is usually compose of the young, old and disabled on wheel chairs and this is not evident.
She was a little girl who had made herself known throughout the nation by her singing songs of success for the disabled on TV.
Services to those of the NINDSAs a very disabled on neurological disorders, including malfunctions in the structures of this brochure.
Assuming it's compiled into your kernel, it can be enabled or disabled on a running system by changing the value of /proc/sys/kernel/sysrq.
To disable a service double click on it and where it says startup type simply select disable, The service will then get disabled on the next system reboot.
I grow most of my garden produce for my family, can, and that takes every ounce of energy I have, and I am disabled on top of this, but this can not stop me.
Each display has options to ' check ' and ' uncheck ' and you can choose one based on the number of displays you want enabled or disabled on the viewing taskbar.
In 3% of cases disabled of is used
This government needs to help the disabled of its country.
This campaign is about nothing more than demonising, and further marginalising the sick and disabled of Britain.
And, do remember that Social Security helps children whose parent dies and the disabled of all ages who need assistance.
Strip the disabled of their benefits, cut tax credits for hard working families, increase child poverty and leave ' em to it.
That lesson applies to all aspects of rehabilitation, from the professional and Olympic athlete to the most disabled of patients.
The old, the poor and the disabled of Muslims and non-Muslims alike were provided for from the public treasury and from the Zakat funds.
This actually went into commercial production, although the expense meant that most of the disabled of the time stayed in manual wheelchairs.
Lies that accuse the poor, the sick, the injured, the disabled of being just lazy-the homeless being just worthless drug-addicts &; alcoholics.
This initiative aims at raising funds for the Movement for the Intellectually Disabled of Singapore (MINDS) and is similarly supported by Southwest CDC.
Mr Kuha now had a chance to explain his concerns to the person in charge, and would do as good a job as anyone in putting a case for the beneficiaries and disabled of New Zealand.
In 2% of cases disabled after is used
Disabled after this video was shot.
A challenging twist occurred in Turcotte? s life when he became disabled after a riding accident.
Some people may only be slightly disabled 20 years after PD first begins, whereas others may be very disabled after 10 years.
Dr Mid-Nite, another blind superhero, and Cyborg, a character similar to Iron Man who became disabled after an experiment went wrong.
People who become disabled after reaching the age of 65 will have had no disadvantage on grounds of disability during their working lives.
According to the committee's report, five men were killed and 137 suspects left disabled after police torture in Lahore in 2011 and so far in 2012.
Adrian Underwood (Pic:PA) A cleric has been left disabled after blundering doctors failed to spot a tumour in his brain that grew to the size of a lemon.
ABD prevalence is an instant measure defined as the number of individuals in a population which remain disabled after having suffered a stroke or a TBI 27.
But now again after this report is rendering, the browser back history as we come from parent folder to the report is getting disabled after the report rendered.
He became disabled after walking normally for a year and had to crawl for 9 years before walking again with the aid of a wooden stick because clutches were not available at that time.
In 2% of cases disabled due is used
Like you I am in constant pain &; also registered disabled due to wide spread arthritis.
Across the hall from me is a woman disabled due to constant pain: she'd LOVE to be cured.
But being in constant pain and taking a stupid amount of medications means I am disabled due to pain.
Mayor Greg Brudnicki sat next to his father, Adam Brudnicki, a WWII veteran that became disabled due to his service.
This kind of thinking, that people are poor or disabled due to a personal failing, a weak character, is rooted in Christianity.
Annette Jimison Michael, I became disabled due to a traffic accident, where a young kid crashed into our car and tore it apart.
With them, I was constantly losing my connection and then the configuration would get disabled due to not acquiring the ip address.
A decade ago when he was in high school, John Paul, or JP, was diagnosed with a brain condition making him disabled due to psychological trauma.
Out of 169 disabled people in Muyinga, from a sample of 2,068 people, 45 percent became disabled due to diseases that could be prevented or treated.
Those rendered disabled due to their dedication to the battlefront giving the first place to the motherland and not to their wives or children are proud sons of a heroic generation.
In 2% of cases disabled through is used
Its of no use as its disabled through the software installed on our STB.
The whole Wesley Centre is accessible by the disabled through lifts, escalators and ramps.
Our aim is to improve the quality of life for the disabled through the development of training and employment opportunities.
Even in a hospital with an operating theatre in the next room we see healthy babies become disabled through lack of oxygen during birth, etc (just an example).
That's something else you support, isn't it? Is this continued oversight by the Guardian accidental or moral cowardice? People do not become disabled through choice.
The deputy said that the U-turn on this meeting came on the back of a national U-turn as regards the proposed 10 million cuts which would affect the disabled through cuts to personal assistant hours.
In 2% of cases disabled into is used
Force the poor and disabled into the streets to work.
The way round the problem is to bring the disabled into the wider community.
What I can tell you is that removal companies do take the disabled into consideration.
A bit more tax on the rich, but for that, we'll allow you to screw the poor, sick and disabled into the deck.
All communities should accept **26;22360;TOOLONG, military and the police, war widows and disabled into their localities with open arms.
AT THE HANDS OF THESE PEOPLE YES WE WILL!!! Why doesn't this government just dig a huge huge hole and throw all the disabled into it and gas us.
In 1% of cases disabled without is used
But others are just the law according to Facebook and can lead to a personal page being removed or disabled without warning.
Well they have taken benefits from the sick and disabled without a public backlash and now they are coming for everyone else.
All too often, people with MS from deprived backgrounds bear their MS attacks silently, becoming more disabled without any support.
Basically you will be able to continue living the lifestyle you led previous to becoming disabled without incurring more debt or becoming a financial burden unto others.
A Live-in Caregiver is a person who provides child care, senior home support care, or care of a disabled without supervision in a private household in Canada in which the person resides.
In 1% of cases disabled under is used
Sometimes respiratory or neurological functioning is so severely affected that an individual will satisfy the requirements to be considered disabled under the regulation.
In 1% of cases disabled like is used
Disabled like meat to be poked, packed and despatched.
The inspirational medic told his patients: ' The day will come when there will be an Olympic Games for the disabled like you.
Comments I think this is a perfect legitimate treatment for the most severly disabled like Ashley who show no hope of ever improving.
In 1% of cases disabled including is used
Facilities for the disabled including ramps, hearing loops and dedicated wheelchair spaces are provided.
The names, addresses of the disabled including the names and addresses of those accompanying them are also noted.
Speed News The National Association for the Blind (NAB) today demanded establishment of a separate university in Maharashtra exclusively for the disabled including the blind.
Nevertheless, there is a glimmer of hope in the Persons with Disability Act (Act 715 of 2006) in which provision is made for job opportunities for the disabled including the deaf.
In 1% of cases disabled during is used
Interrupts must be disabled during this procedure.
She then became disabled during the notice period.
The first one can be enabled or disabled during program writing.
Among 20% of injured people have become disabled during the 2nd uprising (Intifada).
If you have any magic immunity skills or abilities, try to pop it just before you use Unholy Rage so you don't get stunned or disabled during its duration.
The proceeds from the sales will be utilized for the benefit of the war heroes who served since the World War I, now retired or disabled during their service.
Persons become handicapped and disabled during war period occupy themselves by involved in playing sitting volley ball game, without getting glued to one place.
The matter would become more complicated if you were not actively employed at the time of your termination, such as becoming disabled during a temporary layoff.
So, if the employee becomes disabled during the notional working notice period, the disability insurance is no longer available to provide wage-replacement benefits.
They want India to perform miracles to remake something- the PC system- that was conceived by rape, deformed at birth, malnourished and further crippled/ disabled during its life.
In 1% of cases disabled before is used
Studies show that a 20-year-old worker has a 3 in 10 chance of becoming disabled before reaching full retirement age.
There, he spent four years training doctors and working with the disabled before relocating to Kunming, the capital of Yunnan.
Disability income insurance will ensure that you continue to have a source of income should you become disabled before your planned retirement age.
Of today's 20 year olds, one in four will become disabled before age 67, and one in eight will die before that age; Social Security provides protection against loss of income in those situations.
In 1% of cases disabled because is used
If you are ill or disabled because of an accident, you need to talk with ACC first.
A friend's daughter was born disabled because of a prescription drug for scabies containing pesticide, for instance.
People become disabled because of all the social, cultural, economic, political and other factors that prevent them for participating fully in society.
They're not going after the disabled because of cuts, they have already stated that it's not about cost cutting on the news and that was Cameron's own words.
And despite all of this, what do we get in return? Austerity, lower living standards and attacks upon the poor, sick and disabled because of a broken economy that continues in recession.
Some people with a disability were born with the disability or became disabled because of lack of adequate medical care at the appropriate time eg victims of polio or other childhood illnesses.
In 1% of cases disabled among is used
How we behave with the disabled among us tells us what kind of a people we are.
I could feel that I am disabled among everybody in my own eyes as well as others.
In 1% of cases disabled against is used
During his first week in office, he signed the Lilly Ledbetter Fair Pay Act, which protects women, minorities, and the disabled against unfair wage discrimination.

redpajama_set_name: RedPajamaCommonCrawl


If you're the parent of a teething baby or toddler, these healthy homemade teething biscuits are your new best friend.
Preheat oven to 350 degrees. Prepare a baking sheet with parchment paper or a silicone baking mat.
Add banana and coconut oil (and any vanilla or spices you may be using) to the blender and puree until mixture comes together in a dough.
If the dough is very sticky to handle, you can pat a little flour (gluten free or wheat flour) onto the exterior of the ball to make it easier to handle. If the dough is too dry, you can add a little additional coconut oil.
Divide the dough into 12 balls or sections. Pat out each ball into a little baton about 4 inches long and 1 to 1 1/2 inches wide, and about 1/4 inch thick. Round the edges of each baton with your fingers so there are no sharp edges.
(Alternatively, you can roll the entire dough ball out into a rectangle about 1/4 inch thick and slice it into 12 rectangles. Round the corners of each rectangle and make the shapes roughly even. I've found that shaping each baton works better for me than rolling and slicing, but you can do what works best for you).
Place evenly on a baking sheet so that none of the batons are touching. Bake at 350 degrees for 10 minutes. Flip and cook another 5-10 minutes, or until the edges are golden and the centers are set but not too crunchy.
Allow to cool completely. Store in an airtight container at room temperature, in the refrigerator, or the freezer.
How do you tell if you need to visit an urgent care vs. the emergency room?


Octopus Go is an electricity tariff with a bonkers cheap 5p / kWh rate for four hours every night (between 12.30 and 4.30am). It was designed with EV-angelists in mind, because those sweet four hours let drivers charge up while they're asleep, and keep fuel costs around 1p per mile.
Here's the answers to every question you've ever had* about Go, all in one place.
For more info on this tariff, and others that might suit you if you drive an electric car, have a read of this blog.
For more information on all things electric cars, including smart chargers, our domestic vehicle-to-grid trial, Powerloop, company 'salary sacrifice' schemes, government grants, green taxi incentives, and a load of other exciting EV-tunities, chat to the amazing folk over at Octopus Electric Vehicles.
*Any questions we've missed? Drop us a line.
What are the prices involved in the Go tariff?
And a standing charge of 25p/ day.
What is my day rate and standing charge?
Your day rate varies a little bit depending on where you are in the UK, but generally hovers between 13-14p/kWh. Your standing charge is 25p / day.
You can get a quote for your day rate by going to www.octopus.energy/tariffs, popping your postcode in, and finding Go in our current tariffs. You'll see your unit rate (which is the unit price of your energy for all hours outside of 12.30am and 4.30am) and your 25p daily standing charge.
Is the Go tariff fixed?
45 days from the end of your contract, we'll get in contact with next year's Go prices so you can fix again and compare us to the market.
Go, like all Octopus tariffs, doesn't have any exit fees or tie-ins, so you can change tariffs or switch suppliers at any time with no penalties.
Do I need an Octopus smart meter to get on Go?
We've currently paused taking new smart installation appointments as we begin a more controlled SMETS2 rollout over the next few months.
Can I switch to Octopus directly onto the Go tariff?
Go is a smart tariff. This means that you need to have a SecureTM smart meter installed before you can join the tariff. Trouble is, we're not allowed to book you an installation appointment until you've fully switched to us, which means you do need to sign up to Octopus on a standard tariff first in the interim.
All our tariffs have great, competitive rates, and you shouldn't have to wait too long for a smart meter.
There's more information about switching to Octopus for Go here. If you've got any other questions, do get in touch for further information on this, and get a quote to switch to us any time at octopus.energy.
PLEASE NOTE: We've currently paused taking new smart installation appointments as we begin a more controlled SMETS2 rollout over the next few months. If you don't want to wait on one of our standard tariffs in the interim, we'd recommend delaying your switch until we've started taking appointments again.
What if I don't want to get up at 1am to turn my charger on?
Fear not. We partner with Myenergi to pair Go with their acclaimed Zappi charger, which will turn on automatically when the cheap charging period starts. More information about the Zappi here.
Get in touch with Octopus Electric Vehicles' Chargin' Charlie if you want to get your hands on a Zappi.
Can I use my cheap charging period for anything other than charging my car?
Don't want to get up at 1am to put the dryer on? You don't have to. There's some pretty neat stuff you can programme, too, thanks to our smart integration with Alexa.
Is there a Go gas tariff?
No. Octopus Go is an electricity tariff, created for drivers to charge their electric cars. This kind of smart tariff passes on the benefits of the UK electricity market's wholesale prices, which are highly variable through the day. Wholesale gas prices don't really vary throughout the day, so a Go gas tariff wouldn't really be able to have that same amazing off-peak rate.
If you're a dual fuel customer, we can supply you gas too, of course. Just choose one of our standard gas tariffs, which you can get a quote for any time at www.octopus.energy/quote.
Can I be an electricity-only customer, and get my gas from another supplier?
Yes! Choose 'electricity only' at signup.


The Hollo-Blast Jr. is designed to clean pipe or tubing from 3/4 inch to 2 inch I.D. in 1/4 inch and 1/2 inch increments.
The tool is mounted on 3/8 inch pipe lance for the length of tubing to be cleaned. A tungsten carbide lined reducer adapts the 3/8 inch lance to standard straight 1-1/4 inch thread for attachment to blast machine hose. Operation of the Hollo-Blast Jr. is the same as Hollo-Blast. Air consumption is 80 CFM. Recommended abrasive size is 30 mesh or finer.


text:
Briarcliff Daily Voice serves Briarcliff, NY
Rivertowns
serves Dobbs Ferry, Hastings & Irvington
Stephen King Apple TV Plus Miniseries 'Lisey's Story' Films In Westchester
Hollywood came to Tuckahoe as star Julianne Moore and the cast and crew of Stephen King's "Lisey's Story" filmed in the village. Photo Credit: Contributed by John Larkin
Filming for the latest Stephen King adaptation, "Lisey's Story" made its way to the Hudson Valley, bringing Hollywood to a small Westchester village.
Academy Award winner Julianne Moore was among the cast and crew to take over Tuckahoe Village Hall and the Public Library on Wednesday, Dec. 11, as filming for the much-anticipated Apple TV Plus miniseries based on the Stephen King novel continued in the tri-state area.
Film equipment and production trucks could be seen lining Main Street and Columbus Avenue in Tuckahoe for several hours on Wednesday, as the crew filmed scenes for the miniseries that is being produced by J.J. Abrams.
"It was interesting to see how the film crew changed the familiar appearance of Village Hall and the Mayor's office to suit the needs of the scenes shot in those areas," Tuckahoe Mayor Greg Luisi said. "It will be exciting to see the finished product when it airs."
Trustee Omayra Andino noted that King even made his way to the village to visit the set and spend some time in the area.
"I'm really proud that Tuckahoe was chosen for the filming of Stephen King's 'Lisey's Story,"' she said. "It's a testament to the character and heart of Tuckahoe, which I'm sure will shine through on screen. Stephen King was so kind when he visited the set. This is a great moment in our little Village and I'm grateful for the opportunity to serve during such a time as this."
Other notable cast members starring in "Lisey's Story" include Clive Owen, Joan Allen, Sung Kang, and Dane DeHaan. The production has been in the works for more than two years before the miniseries got off the ground.
"Lisey's Story is my favorite of the books and I would love to see that done, especially now that there's a kind of openness on the streaming services on TV and even the cable networks," King told Variety in 2017. "There's more freedom to do stuff now and when you do a movie from a book, there's this thing that I call the sitting on a suitcase syndrome.
That is where you try to pack in all the clothes at once and the suitcase won't close. So it's tough to take a book that is fully textured, and do it in two hours and 10 minutes. But as a TV show, you have 10 hours."
The miniseries will tell the tale of a widow - played by Moore - of a successful novelist - played by Owen - who is terrorized with an obsessed fan of the deceased writer. King is expected to write all eight episodes of the miniseries and will serve as an executive producer, alongside Moore.
Area College Athlete Dies After Accident
Snowfall Projections Increase For Sprawling Weekend Storm
Briarcliff Daily Voice!


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05.21.2015 Sports
Baseball: Settlers sweep up their first county title since 2003
By Bob Liepa
Southold's players turned a team photo into a fun photo after capturing their first county championship since 2003. (Credit: Bob Liepa)
SUFFOLK COUNTY CLASS C FINALS, GAME 2 | FIRST SETTLERS 6, WHALERS 0
After prevailing in an epic thriller of an opener to the Suffolk County Class C baseball finals, what does Southold do for an encore?
Well, for starters, its No. 2 pitcher flirts with a no-hitter. And then the First Settlers win their first county championship since 2003.
When Southold shortstop Noah Mina squeezed a popup hit by Pierson/Bridgehampton's Matt Burke for the final out of a 6-0 victory on Thursday, the First Settlers went into celebration mode. They hopped for joy, hugging each other by the pitcher's mound at Mashashimuet Park in Sag Harbor, having swept the series in two games. It is quite a turnaround for a team that went 4-12 last year.
Southold coach Mike Carver said he believes it is the third county title in team history.
Pierson/Bridgehampton, a state finalist last year, had won the county crown the past three years.
Because Nassau County doesn't have a Class C team, the First Settlers (20-2) advance directly to a Southeast Region final on June 6 against an opponent to be determined.
In the first game of the county finals the day before in Southold, the First Settlers had prevailed in eight innings, 5-4, on a walkoff single by Liam Walker. For all the thrills and chills that game brought, Game 2 belonged to the Southolders virtually from start to finish. They hit the ball well (11 hits) and put up four runs in the second inning for an early lead. In the meantime, sophomore pitcher Pat McFarland (5-2) took a no-hitter into the fifth inning. But Pierson/Bridgehampton's first batter that inning, Ryan Chisholm, broke up the no-hit bid, driving a single past diving third baseman Greg Gehring.
McFarland, whose command was on, stayed strong, though. The right-hander finished with a two-hitter, the only other hit he allowed being a two-out single up the middle by John Chisholm in the sixth. McFarland walked one and struck out three.
Shayne Johnson and Sean Moran delivered three hits each for the League IX champions.
Run-scoring doubles by Dylan Clausen and McFarland highlighted the four-run rally in the second, with McFarland's drive down the left-field line coming on a hit-and-run play. Moran scored on a Gehring groundout and Clausen charged home on a wild pitch for the other runs.
The First Settlers started off the fourth with successive singles by Clausen, Gehring and Luke Hansen to stretch the lead to 5-0. Johnson later singled in the sixth run.
Southold won five of its six games against the Whalers (14-8) this season.
Bob Liepa is the sports editor for Times Review Media Group, where he has worked since 1992. Raised in East Meadow, the Long Island native has won both Writer and Sportswriter of the Year from the New York State Press Association.
Email Bob Liepa Email Created with Sketch. Email Bob Liepa
Pierson/Bridgehampton
01.17.2021	Sports
Track & Field: Greenport senior shines in season-opening loss
Kevin Azama is making up for lost time. It had been a long time since Azama last competed in...
Baseball: Teaming up with Riverhead Little League to play ball this summer
Even back during the darker days of the COVID-19 crisis in New York, Riverhead Little League's leadership had remained...
With season canceled, wood bat tournament gave Mattituck seniors one last chance to play ball together
The welcomed sounds of the crack of a bat and pitched baseballs popping into catchers' mitts were back. Although...
Summer season in 'holding pattern' for North Fork Little League
Baseball is coming back. At least for some leagues. Regardless of whether Major League Baseball sees the field again...
Hamptons Collegiate Baseball League cancels 2020 season
The Hamptons Collegiate Baseball League will not play ball in 2020. The league's 13th season will have to wait...
Local Little Leagues determined to play ball in 2020
This is ordinarily a big time of the year for Little Leagues, but these are not ordinary times. Little...


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Professor Yiu-tung SUEN
Assistant Professor, Gender Studies Programme, Chinese University of Hong Kong
Yiu-tung SUEN is Assistant Professor of the Gender Studies Programme, and Founding Director of the Sexualities Research Programme, at the Chinese University of Hong Kong. His studies inform and are informed by critical current debates on sexual orientation and gender identity laws and policies, particularly with a view to providing empirical evidence which has been largely absent in Asia. He served as a consultant and data analyst for the United Nations Development Programme Being LGBTI in Asia programme. He sits on the research advisory board of Open for Business. Dr Suen's research has a strong component of knowledge exchange. His research has been cited in a good number of judicial review cases in the Hong Kong court and international and local media outlets.
All Sessions by Professor Yiu-tung SUEN
June 11: LGBT Asia Research Presented by Ropes & Gray
LGBT Asia Research Presented by Ropes & Gray


text:
Guys i need your opinion on this one..
justonequestion
August 11, 2016 at 9:16 am #107968
So i want a guys honest opinion on this one
Met a guy, over a month ago, he said he hasnt been in a relationship for seven years, however hes dated..
When im with him, which is mainly just weekends its fine however when im not with him he doesnt basically give me any attention at all. I have told him this, with just a extra message or something. I think when your first dating someone it should be the most easiest thing, flirting etc.. He says it is hard for him and to give him time, he said he's use to being selfish and being on his own and into his career. I think though if you really like someone you will make the effort.
Right now I just feel like im being used for his spare time, which is mainly weekends and only his career comes first, i respect that he has a career goal but come on, how much time does a guy need? Im not waiting around for forever..
Be honest guys. Whats up with him?
MtnMan77
It doesn't sound like he's really that into you. From my perspective, being a guy who's really into a girl right now, I've been texting or calling her every couple of days or so and definitely trying to make date plans regularly.
rsjay8828
It sounds like he may have been hurt really bad in the past and is using that as his own way to not open up to someone new, sort of always has his guard up. Now think about that, are you sure you want to be involved with someone like that for say 7 years. Think about it, that relationship must have had a real impact on him. Just a thought.


House situated at Chavadimukku Gandhipuram.
Doctors, Bank Employees, Engineers Preferred.
Kitchen, Work area, Out side Kitchen and Bathroom.
First Floor : 2 Bedrooms, Hall, Common Bathroom, Balcony and Open Terrace.
Chavadimukku (NH 47) – 150 Meter.
Loyola School – 2 KM.
Sreekariyam Junction – 1.5 KM.
College of Engineering Trivandrum – 1.5 KM.
All other essentials in 1 KM radius.


text:
'''SSI-92''' (project designation '''CY-6''') was the sixth launch of [[Cycloon|Project Cycloon]] on October 5, 2019. It was the first interstate Cycloon flight (and to-date longest distance), the first launch of a poly tubing ZPB, and the first ZPB flight for which telemetry at equilibrium and descent was acquired since [[SSI-20]]. This enabled the acquisition of valuable thermal data and verification of equilibrium altitude predictions. Continuing a trend, the payload was lighter still than that of its predecessor, [[SSI-91]].
'''Avionics''': TinyGPS, Teensy 3.2, BMP 280 transmitting at adjustable intervals over Rockblock. A SPOT Trace was accidentally omitted. This set of avionics was recovered from [[SSI-91|CY-5]]. Controlled novel cutdown mechanism.
[[File:Ssi91profile.png|400px|thumb|right|The altitude profile resembled a standard latex launch due to reasons discussed in the synopsis]]
'''August 5 2011 PDT:''' Balloon released from a running start. Initial motion to the east at an ascent rate of 3.8 m/s --- significantly faster than the target ascent rate of 2.5 m/s.
'''October 5 1100 PDT:''' Balloon released --- no running start needed. Free lift was measured at approximately 0.5 kg. Initial ascent at about 2.5 m/s. Nearly no horizontal initial motion, followed by a gradual drift to the southwest and then southeast.
'''October 5 1219 PDT:''' Balloon appeared to equilibrate at 17.43 km, having ascended at 4 - 5 m/s in the second half of its ascent. Within significant figures, this was essential equal to the predicted equilibration altitude of 17.37 km. At the point the balloon had been moving due east and had been crossing the Diablo range.
'''October 5 1225 PDT''' Balloon reached a maximum altitude of 17463 m, at 36.929, -120.947 over the eastern foothills of the Diablo range. In the ensuing hours, the trajectory fluctuated within the rates of +/- 0.3 m/s, which was considered a very successful equilibration.
'''October 5 1547 PDT''' At this time, the balloon was over the peaks of the Sierra Nevada (John Muir wilderness), yet still held an altitude of 16.4 km.
'''October 5 1602 PDT''' GPS lost lock over 37.198, -118.72 at an altitude of 16330 km. This sparked intense speculation, and the rapidly dropping temperature of -22 C was momentarily blamed. During the lock, the barometer and Iridium triangulation functioned as telemetry.
'''October 5 1729 PDT''' In the previous 15 minutes, Iridium had been reporting with increasing confidence from Nevada, so an interstate transition was declared. By this time, the balloon was just above 15 km in altitude, having stalled its descent over the past half hour. Now, however, descent began in earnest.
'''October 5 1839 PDT''' Altitude was around 13.8 km, and descent rate increased to around 1 m/s, marking an inflection point. Landing was predicted near St George, UT.
'''October 5 1903 PDT''' Altitude near 11.5 km. Descent rate stabilized near 2 m/s and fluctuated around this value for the next hour or so.
'''October 5 1917 PDT''' GPS signal returned at an altitude of 9745 m. The temperature was -37 C, disfavoring the cold hypothesis. Instead, the threshholds of 10 km and 1600 PDT were noted with suspicion.
'''October 5 1924 PDT''' At an altitude of 8914 m and a descent rate just above 2 m/s, an impact at 2030 PDT near US-93 was predicted.
'''October 5 1828 PDT''' Landing declared at a ground elevation of 1511 m. Descent just before impact had slowed somewhat, consistent with predictions.
'''August 5 2059 PDT:''' After almost an hour of steady ascent, balloon reaches a maximum altitude of 10.298 km over (37.1502, -121.4077). Ascent rate had fluctuated above and below the initial rate of 3.8 m/s. In theory, a slight acceleration in ascent was expected. By this time the balloon was in the jet stream layer travelling north at nearly 30 m/s.
'''August 5 2103 PDT:''' Balloon reported an altitude of 10.291 km, a highly unexpected measurement. In retrospect, it is believed that venting began at this altitude, but the vent hole was far too small to vent the necessary volume, leading to envelope rupture. The resulting leakage prevented the balloon from reaching the calculated equilibrium altitude of 14-15km and caused what more resembles a latex profile than a zero-pressure balloon profile.
'''August 5 2055 PDT:''' Balloon reported first definitive descent at an altitude of 9.905 km.
'''August 5 2213 PDT:''' After an hour of descent at 2.5 m/s - 3.0 m/s, balloon reported a ground elevation of 29 km. The landing site was less than 100 m from a road in an apple orchard.
'''August 9 0316 PDT:''' Last RockBlock transmission received, with no indication of movement since flight termination.
{{balloon-footer}}
[[Category: High Altitude Balloons]][[Category: Balloon Launches]]
Otober


Sara Trunzo is an award-winning songwriter specializing in alternative country, Americana, and folk writing and performance. A background in farming, sustainability, and rural community organizing informs both her craft and content. In her teaching, facilitation, and coaching- Trunzo helps students cultivate songs that instigate personal and social healing, truth-telling, and transformation.
Trunzo draws influence from- and has studied with- master songwriters Darrell Scott and Mary Gauthier. Her debut EP 'thanks birdie' dropped in 2017; she toured nationally in 2018; and a full-length album 'Dirigo Attitude' is slated for an early 2019 release. She holds a BA in Environmental Writing from Unity College. She lives in Nashville, Tennessee, Waldo County, Maine, and on the road.


This entry was posted on Monday, September 3rd, 2012 at 1:30 AM and is filed under Adaptive Reuse, Collaboration, For Sale!.	You can follow any responses to this entry through the RSS 2.0 feed. You can skip to the end and leave a response. Pinging is currently not allowed.


What is the best price for a return flight from Moscow Domodedovo to Platov International, Rostov-on-Don?
How many airlines fly direct from Moscow Domodedovo to Platov International, Rostov-on-Don?
There are 2 airlines who fly direct from Moscow Domodedovo to Platov International, Rostov-on-Don.
How many flights are there a week from Moscow Domodedovo to Platov International, Rostov-on-Don?
There are 15 flights per week from Moscow Domodedovo to Platov International, Rostov-on-Don, as of March 2019.
How long does it take to fly from Moscow Domodedovo to Platov International, Rostov-on-Don?
1h 45min is average flight time from Moscow Domodedovo to Platov International, Rostov-on-Don.
Which airline is the most popular from Moscow Domodedovo to Platov International, Rostov-on-Don in March 2019?
S7 Airlines is most popular airline from Moscow Domodedovo to Platov International, Rostov-on-Don in March 2019.
Skyscanner is a fast and simple travel search engine that helps you to find cheap flights and great prices on flights from Moscow to Rostov-on-Don. We compare hundreds of flights from all major airlines and travel agents, finding you the best deal on cheap plane tickets to Rostov-on-Don from Moscow.


Every business requires high level security so that to ensure it does not lose goods and equipment. It is a good idea to install security systems in your business premises so that to improve the security, but it is also good for you to install modern industrial doors. If you want to install industrial doors for your business, it is advisable for you to use the services of a reputable company. By reading this article, you will learn more about some of the best reasons why you should buy your industrial doors from a reputable company.
One of the reasons why it is beneficial for you to purchase your industrial doors from a trusted company is that you're going to be provided with high-quality industrial doors. When you have high-quality industrial doors in your business, this is going to improve the security of your business since no intruder is going to easily get past the doors. It is critical that you purchase high-quality industrial doors so that you can make huge savings on your money because you're going to incur fewer maintenance and repair costs because of the reduced wear and tear. In addition, when you have high-quality industrial doors, you're going to increase the aesthetic value of your business and hence improve your reputation.
Another top reason why you should purchase your industrial doors from the best company is that you're going to be offered a wide variety of industrial doors. By purchasing industrial doors from a reputable company, you will be offered a wide range of designs and colors which will make it possible for you to select an industrial door that is going to match your tastes and preferences. It will also be possible for you to be provided with a customized industrial door when you use the services of a trusted company. When you purchase industrial doors from a trusted company, you're going to be offered industrial doors such as roll-up doors, insulated garage doors, fire rated doors and security gates.
Another top advantage of buying your industrial doors from a reputable company is that you're going to be provided with friendly prices. If you, therefore, want to ensure that you save money on the installation of your industrial doors, then you should use the services of the best company. If you want to enjoy the above benefits, it is highly recommended for you to purchase industrial doors from a reputable company. To learn more about the other top advantages of purchasing your nostrils from the best company, visit this site.


text:
Emergency est une ONGI fondée par le chirurgien de guerre italien Gino Strada. C'est une association humanitaire internationale qui s'occupe aussi de la rééducation des victimes de la guerre et des mines terrestres. Emergency fournit une aide médicale dans des zones de guerre ou de grande pauvreté (Irak, Afghanistan, Soudan, Sierra Leone, Cambodge, R%C3%A9publique centrafricaine) et aux migrants dans sa clinique italienne à Palerme.

Annexes

Sources et bibliographie

En italien
  Gino Strada, Pappagalli verdi - Cronache di un chirurgo di guerra, Feltrinelli, 1999, 164 p.
  Gino Strada, Buskashì - Viaggio dentro la guerra, Feltrinelli, 2002, 202 p.
  Giulietto Chiesa Vauro, Vauro, Afghanistan anno zero, Guerini e Associati, 2001, 172 p.
  Emergency, Medici di guerra - Inviati di pace, Guerini e Associati, 2002, 153 p.
  Vauro, Principessa di Baghdad, Guerini e Associati, 2003, 157 p.

En anglais
  Gino Strada, Howard Zinn, Green Parrots: A War Surgeon's Diary, Charta, 2005, 160 p.
  Howard Zinn, Just War, Charta, 2006, 72 p.

Liens externes

  Site officiel
  Section américaine
  Section anglaise

Aide humanitaire
Association fondée en 1994
Association ou organisme caritatif
Association ou organisme d'aide aux personnes handicapées
Association ou organisme ayant son siège en Italie
Organisation non gouvernementale humanitaire
Organisation non gouvernementale internationale
Organisme fondé en 1994
Organisme sans but lucratif
Lauréat du prix Antonio-Feltrinelli
Association ou organisme d'aide humanitaire

redpajama_set_name: RedPajamaWikipedia


Zachary Wu writes a detailed tactical analysis about the Premier League match that ended Everton 4-0 Manchester City.
Koeman's Everton hosted Guardiola's City in a clash of ideologies. Koeman being much more pragmatic while Guardiola far more idealistic. Everton were in decent form, having collected 10 points out of a possible 15. City's form was also on the up, winning 4 of their last 5 games while conceding just 3 goals within that period. It was all set to be a closely and tightly fought encounter. However, that only translated to the chances created but not the scoreline.
Koeman set up Everton in a 3-4-3/3-5-2 formation, with Barkley joining Lukaku and Mirallas to form a front trio when they had the ball and then dropped into midfield to form a 3-5-2 formation when the ball was lost. Due to the lack of possession Everton had, Barkley was forced deeper and hence was constantly seen as part of a midfield three. The formation actually worked out well in the end, as City's attackers played narrow and had to rely on fullbacks giving the width. This meant that Everton could crowd the centre with 3 players, then use their wingbacks to engage City's fullbacks high up the pitch and pin them back in their own half or force them towards the touchline. With a man orientated approach in midfield, this made them very hard to play against.
Koeman, an astute tactician, knew how to play to their strengths. He had a fast, strong and powerful striker in the form of Lukaku who could get behind the City defense with long balls or use his aerial ability to win headers against the City centre backs and then lay balls off to Mirallas and Barkley who were often in close support. Lukaku received 31 passes, 15 of which were long passes while playing 17 short passes out of 18 passes himself which is an indication of Koeman's strategy.
He also was aware that Everton were not good at building out from the back and would be vulnerable to City's zonal orientated press. Hence, he had instructions for Robles to reduce playing out from the back and kick it long. The difference between Robles' kicking is very different to Bravo who was instructed by his manager to keep the ball on the ground. This strategy was pretty successful, considering that Everton scored 3 goals after a long ball into the right half space.
Koeman also instructed his team to sit deep and crowd the dangerous zone 14, the area just outside their penalty box. For large parts, they fared decently against a world class attack of Sterling, Sliva, Aguero and De Bruyne, restricting them to just an Expected Goals tally of 0.83. However, the aforementioned quartet were just whiskers away in tucking away potential goals, with De Bruyne the architect of many of the moves. There was also a (very soft) Sterling penalty shout. If City had finished one of those chances, it could have been a very different scoreline.
After experimentation with half backs and even a back 3, Guardiola opted for a traditional back 4 with overlapping wingbacks with the attackers narrow, trying to exploit the half spaces and the channel between Everton's midfield and defense in a 4-4-2 diamond formation. On paper, it seemed like a good idea, trying to gain a qualitative and quantitative advantage in the centre. Also, this formation had worked magnificently in City's last game, a 0-5 thrashing away of West Ham in the FA Cup.
However, it did not go to plan. Compared to the West Ham game, when City's fullbacks pinned West Ham's wingers back, against Everton the advancing fullbacks were pinned back by Everton's wingbacks and were not able to consistently influence play in the final third. Toure, who often had to drop deep to form a temporary back 3 to bypass Mirallas and Lukaku's pressing often had little pass options through the centre. As a result, City defenders were often forced to play balls that were unsuitable for clean progression of play.
In this snapshot, Otamendi (yellow) plays a dangerous ball to David Sliva (orange) due to a lack of available options. He has few pass options, with possible options like Zabaleta eliminated as Barkley (red) is in close proximity. By playing a dangerous high ball to David Sliva (orange), who is not good in the air, Otamendi is forcing a situation of qualitative inferiority, forcing City to lose the ball.
Subsequently, De Bruyne and Sliva (purple) had to drop deep to receive balls from Toure.
This resulted in City having fewer men in the final third to attack Everton's backline. Also, the Everton backline and midfield displayed high levels of compactness and staggering in midfield, making them almost impossible to play through at times, leaving the City attackers always in their cover shadow or being tightly marked. Sterling, the most technically inept out of the attackers, struggled to get the ball under control in tight spots and lost the ball frequently. Also, by playing this diamond shape, City were faced with a 3 vs 2 quantitative inferiority upfront which allowed Everton to have a spare man against the pacey Sterling and Aguero. With always a sweeper to cover the 2 Everton centrebacks who were man marking tightly, it was almost impossible for City to break through and create clear cut chances.
What was said earlier is illustrated in this snapshot. Sterling has no options to pass to, with all players tightly marked and Williams (pink) the sweeper to ensure Everton have a quantitative superiority at the back). Sagna (out of frame) is closely marked by Baines (out of frame), rendering him as a non-existent passing option. Left with no options, Sterling plays it back to Otamendi.
Having taken the lead, Koeman saw no need to have any major changes. To his credit, his team had executed his game plan magnificently, limiting City to just a few half chances. There were some minor changes though. After Schneiderlin came on, he joined the midfield trio while Barkley went up front. There was no more or little sliding in a 3-4-3/3-5-2 shape, but more of a permanent 3-5-2 shape with Barkley and Lukaku up front. The rest of the subs were to replace tired legs.
Seeing his most creative players being constantly harassed when on the ball, he decided to move one of them deeper and putting Iheanacho just off Aguero like a second striker. Sliva played Zabaleta's role as a shuttler as one of the sides of the diamond, giving him more time to pick laser passes and not being harassed by the Everton centre midfielders. This however, (possibly due to lack of options from the bench) made Sterling play as a no 10. This is not the most ideal as his first touch, press resistance and strength are not his strongest assets. His pace would have been much more needed in wider areas where he could stretch opponent lines or perhaps take a man on. Without a change in formation, personnel or tactics, City's play remained roughly the same for the remainder of the game. Perhaps a formation with much greater width would have been better, allowing City to get behind Everton's wingbacks and take advantage of the sliding of the midfield trio to exploit the half spaces.
One must be wary of the media attention after the game. Many media outlets were calling this a tactical masterclass from Koeman or that Guardiola is a "fraud" who can only work with brilliant players and has been tactically found out. This is far-fetched. City despite all their flaws in their set-up, had a better xG tally than Everton, with Everton just 23% favourites to win the game, let alone by this score line. Also, Guardiola is just 3 points off 2nd place and has more points this season than last year's City team. I wouldn't call that a failure by any stretch.
City must have felt hard done by losing this match, especially by this score margin. The City attackers in general did well and were often just a whisker away from prodding the ball into the net, with Aguero, Sterling and Sliva all coming close. Kevin De Bruyne created many chances for the attackers too. Others were extremely culpable, Clichy playing a poor pass to lose the ball for the first goal, Toure taking a heavy touch for the second and Bravo letting Lookman's shot between the legs. Many critics have called Bravo to be dropped too. The title race is certainly over for them.
Everton must feel very smug with the result, having taken advantage of City's errors ruthlessly. They scored 4 goals with just 4 shots on target. On transitions and at crosses, Koeman's teams are deadly. However, they are not going to face teams every week that play such a high line or score 4 goals with just an Expected Goals value of 0.58. This shows they were never good enough to justify their 4 goals scored. They will struggle against parked buses if they fail to create high quality chances.
Zachary Wu is a fervent Manchester City fan. Ligue 1 and Serie A enthusiast and an advocate for attacking football.
Am aspiring manager, yearning to work at the highest level, Zachary is fascinated with tactics and systems of Bielsa, Sampaoli and Pochettino.


Europrofil develops, manufactures and sells light gauge steel profiles in the Nordic market. Europrofils products are primarily used for the mounting of various plasterboard or other sheet materials in the construction of interior walls, exterior walls and ceilings.
Profiles are manufactured from hot galvanized steel with different surface treatments and thickness through a cold-forming technique into various shapes to achieve requested wall properties such as sound reduction, stability and surface demands.
Visit www.europrofil.se for more information.
This EPD has been registered as an ECO Platform EPD with ECO EPD Reference number 00000043. The International EPD System is a founding member of the ECO Platform and its procedures has undergone a peer audit to be able to use this logotype. All EPDs of construction products from different programmes that carry the ECO logotype are listed here.


text:
N.C. Office of the State Fire Marshal gains new fire investigation unit
Posted By: Angela Brown December 1, 2022
North Carolina Insurance Commissioner Mike Causey who also serves as the State Fire Marshal announced today the department has established a Fire Investigations Unit to assist the state's fire service and law enforcement agencies.
"A fire death or large industrial fire could task local resources," said Commissioner Causey. "This unit is designed to provide additional resources to agencies, which will strengthen their ability to examine the source of fires and protect our state's residents and property."
As of January 1, the FIU will respond on request or assist agencies in investigating all fire deaths, any death in a multi-family dwelling due to carbon monoxide poisoning, fire loss in all state properties and examine fire losses greater than $500,000.
"We cannot have an effective fire prevention and education program throughout the state without being at the front end of fire investigation," said Chief State Fire Marshal Brian Taylor. "It is our duty to report to the legislature the nature of fire problems that exist in our state. This unit will be able to supply the needed data to update the state's Risk Reduction Program."
In 2017, the N.C. General Assembly appropriated funding for two fire investigator positions to jumpstart the unit.
The FIU will be divided into two regions: Retired Alcohol Tobacco and Firearms Agent Bill Marshall will head the eastern region. Catawba County Deputy Fire Marshal Jason Boggs will be assigned to the Western region.
Others contributing to the unit will include two DOI Criminal Investigators (CID) to assist with law enforcement functions. The N.C. General Assembly also sanctioned for an Arson and Homicide Special Prosecutor to assist local District Attorneys to prosecute difficult cases.
About OSFM:
The Office of the State Fire Marshal plays a vital role in protecting lives and property in North Carolina. The OSFM is responsible for training fire and rescue personnel, rating fire departments, administering the state building code, securing property insurance for state-owned buildings and much more. For more information, visit www.NCDOI.com/OSFM or call 919-647-0000.
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1 Second Cup Coffee Co. Restaurant March 7, 2016, 2:04 a.m. View
2 SHEIKH FAZILATUNNESSA ISLAMIC MOHILA COLLEGE College Nov. 16, 2014, 9:36 a.m. View
3 Sony Cinema Hall Cinema Hall Aug. 26, 2014, 11:47 a.m. View
4 Sher-e-Bangla National Cricket Stadium Stadium/Field Aug. 26, 2014, 11:43 a.m. View
5 Segun Restaurant N/A Aug. 4, 2014, 4:54 p.m. View
6 Sanofi Bangladesh Limited Office Aug. 4, 2014, 4:50 p.m. View
7 Space Sweater Limited Mill/Factory Aug. 4, 2014, 4:11 p.m. View
8 sskultur design & culture limited Farm Nov. 22, 2013, 4:51 a.m. View
9 Savar Uniliver Sales Dipo Bazaar July 30, 2013, 1:46 p.m. View
10 Shipahipara Bus Stop Bus Stop July 29, 2013, 12:10 p.m. View
11 Shiromoni Bazar Bus Station Bus Stand July 25, 2013, 11:55 a.m. View
12 Sreerampur Bus Stop Bus Stop July 24, 2013, 1:32 p.m. View
13 Sumon Ahmed House Colony July 24, 2013, 11:25 a.m. View
14 Shankar Bus stand Bus Stand June 16, 2013, 7:37 p.m. View
15 shamoli Bus Stand Oct. 17, 2012, 1:08 p.m. View


Following the launch of the crackling Hyundai i30 N, Hyundai has now unveiled its new N Line trimming package. Initially, it is being launching for the i30 but similar packs are set to be offered for other models in the showroom later down the track.
The Hyundai i30 N Line is for those who want the sporty garnishes of the fully fledged i30 N but don't want the gnarly performance. For the exterior there's a neat aero kit with bespoke front and rear bumpers, designed exclusively for N Line, with silver details.
A set of 18-inch alloy wheels are added, which is the first time this size is being offered for the regular five-door i30. Around at the back is a new twin muffler system, and back at the front is a discreet N Line badge to let everyone know what it is.
It doesn't stop there. Hyundai has also given the interior a makeover with some N-branded suede sports seats, with a perforated leather wrapping of the sports steering wheel. An N Line gear shifter gives the driver some added excitement when driving.
Hyundai says it is planning to introduce similar packages for other models in the showroom, although details on what vehicles exactly are yet to be confirmed. We'd anticipate kits for the popular Tucson, Kona and even the Santa Fe. Hyundai Australia is yet to confirm any local details.


Britain's Queen Elizabeth II walks past a guard of honour with Trinidad and Tobago's President George Maxwell Richards, right, at the Memorial Park in Port-of-Spain, Trinidad, Thursday, Nov. 26, 2009.
Miss Trinidado Tobago Wendy Fitzwilliam kisses to spectators after she was selected the Miss Universe 1998 in Honolulu, Hawaii, May12.
In T&T, a fete is a party that must include calypso, soca and pan music, dancing and native food. A lime is a casual gathering of friends -- to hang out, to pass the time, to chill.
But T&T is more than carnival. There are also many natural resources, including: oil, a bird sanctuary, and a pitch lake no other islands can rival.
Through half a century, T&T can also boast excellence in athletics; whether the sport is football or cricket, the "Black, Red and White" flies high on the Caribbean flagpole of excellence.
Earlier this month, Keshorn Walcott and Olympic athletes representing the second Caribbean nation to win independence from Britain demonstrated that Trinis rule in javelin.
1962 – Trinidad and Tobago leaves the West Indies Federation. Following that historical event, the twin islands gain independence and is led into self-rule by Prime Minister Eric Williams.
1964 - World Steel Band Music Festival debuts.
1967 - Trinidad and Tobago joins the Organization of American States.
1969 - The birth of the Black Power Movement emerges following protests against the arrest of West Indian students at Sir George Williams University in Montreal.
1970 - Government declares a state of emergency after violent protests by "Black Power" supporters who demand a solution to unemployment and an end to foreign influence over the economy.
1972 - State of emergency lifted.
1975 - Strikes by workers in the oil, sugar, transport and electricity sectors paralyze the economy.
1976 - Trinidad and Tobago becomes a republic. Former Governor-General Ellis Clarke becomes president and Eric Williams remains prime minister.
That year, Hasley Crawford won the twin island's first gold in the 100 meter dash at Olympics Games in Montreal, Canada.
1977 - Janelle Commissiong is crowned Miss Universe. She is the first winner of African descent to wear the crown.
1978 - McCartha Linda Sandy-Lewis AKA Calypso Rose is the first female to win the Trinidad Road March competition. Born in Bethel, Tobago, she won the Calypso King competition and for the first time in carnival competitions the title is awarded to a female. Now known as the Calypso Monarch, the title was changed in her honor.
1981 - Eric Williams dies. Tobago's ANR Robinson assumes leadership. George Chambers becomes prime minister. 1985 – Pope John Paul visits T&T.
1986 - Tobago-based National Alliance for Reconstruction (NAR) headed by Arthur Robinson wins the general election.
1987 - Noor Hassanali becomes president.
1990 - More than 100 Islamist radicals blow up the police headquarters, seize the parliament building in Port of Spain and hold Robinson and other government officials hostage for five days in an abortive coup attempt. They are known as the Jumaat al Muslimeen and described as Muslim extremists. After a long standoff with the police and military, the Jamaat al Muslimeen leader, Yasin Abu Bakr and his followers surrendered to Trinidadian authorities.
1991 - Patrick Manning is elected Prime Minister and Basdeo Panday continues to lead the opposition.
1994 - Trinidad and Tobago Television Company merged with the state-owned radio company, National Broadcasting Service. The new entity was called the International Communications Network.
-- Basdeo Panday is elected prime minister. He is the first prime minister of Indo-Trinidadian descent.
1998 - Wendy Fitzwilliam wins Miss Universe. This title is the second for T&T.
2002 - Third general election in three years ends months of political deadlock. Prime Minister Patrick Manning's ruling People's National Movement declares victory.
2003 - President Maxwell Richards is sworn in after being elected by MPs in February. State-owned sugar company Caroni shuts down with the loss of more than 8,000 jobs.
2005 - Regional leaders gather to inaugurate the Trinidad-based Caribbean Court of Justice, a final court of appeal intended to replace Britain's Privy Council. The court hears its first case later that November. At least 10,000 people take part in a protest - named the Death March - against an escalating rate of violent crimes.
2006 - Soca Warriors, Trinidad & Tobago's football team qualifies for the FIFA World Cup in Germany. The soccer team maintains the record of being the smallest nation --both in size and population -- to qualify for a World Cup competition.
2009 - President Barrack Obama visits T&T for Summit of the Americas talks.
2010 - Kamla Persad-Bissesar sworn in as the country's first female Prime Minister.
Air Jamaica operates under the banner of Caribbean Airlines, T&T's national airlines.
2011 - Limited state of emergency is declared by President George Maxwell Richards.
2012 - Keshorn Wolcott strikes gold at London Olympics winning the javelin. The nation tallies another three bronze medals during the 30th Olympiad.


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The March Issue of My Newsletter Is Out!
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