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Joseph Cheng, () (born 19 June 1982) is a Taiwanese model, actor and singer. Although he started his career as a model, Cheng is well known for his role as Jiang Zhishu in Taiwanese drama serial version of Japanese manga Itazura Na Kiss, It Started with a Kiss. Cheng has gained much recognition as an actor in most parts of Asia, particularly Taiwan, China, Hong Kong, Singapore, Philippines and Japan. Cheng released his debut EP, Sing a Song, in October 2009. The title of the EP as well as its title track is a play on the third word in his name, Chang (暢) as a homophone of the word "Sing" (唱) in Chinese.

Early life
Joe Cheng, who was previously (prior to 2005) known as Bryan Cheng, grew up in Beitun District, Taichung, Taiwan. Since his parents' divorce when he was in primary school, he has lived with his father. He also has an elder sister, who lives with their mother.

Acting career
Cheng began his career in the entertainment industry with Catwalk Modelling Agency. He reportedly achieved success as a model within one year of signing. Cheng is based in Taiwan and also counts China, Hong Kong and Japan as his main target markets.

As a model, Cheng was featured in several music videos, including one of Heavenly King Jacky Cheung's. In 2003, he took on the role of the second male lead in The Rose, a Taiwanese drama serial which also starred Taiwanese girl band S.H.E and renowned actress Cecilia Yip. It was this role that kick-started his acting career. Following his rising popularity and the success of his first acting role, Cheng was asked to make a guest appearance as Lucifer in Taiwanese boyband Energy's first-ever idol drama, Dance with Michael, in the same year. Cheng starred as the main lead in two dramas, Nine-ball and Magic Ring in 2004. Although these two serials achieved lukewarm success, Cheng took the role of the main lead in It Started with a Kiss in the following year. This serial achieved high ratings in Taiwan and was popular with audiences throughout Asia. Cheng's popularity rose tremendously as a result. It Started with a Kiss was also Cheng's first collaboration with actress Ariel Lin. The two, who are often touted as one of Taiwan's most compatible on-screen couples, paired up again in the 2007 sequel to It Started with a Kiss, They Kiss Again; as well as Love or Bread (2008) which is unrelated to the Kiss series. Cheng has starred in numerous drama serials produced in Taiwan,China and Japan, but remains most well known for his roles in The Rose and the Kiss series.

As a model, Cheng has modelled for several big-name brands including Puma AG (2003–2005) and adidas (2006–present). He has starred in numerous runway shows for brands such as Marc Jacob's (2003), Timberland, Levi's and Christian Dior (2007) He often also appears at flagship store openings including Hugo Boss (2009). Cheng also endorses several food, jewellery and clothing brands; the most recent being Chinese green tea brand Kang Shifu (for which Cheng starred and recorded a song with Mike He and Taiwanese actress Joe Chen) as well as casual wear brand N+a (with Taiwanese singer-actress Cyndi Wang). He also worked as a spokesperson for Shiatzy Chen.

Excluding drama serial memorabilia, Cheng has released three pictorial books in addition to four calendars and one mini pictorial in conjunction with the release of his EP in 2009. He has also authored two books and co-authored another on his hometown Taichung. He was also featured in a 2006 book on Catwalk Modelling Agency. Cheng has won multiple awards as a model and as a performing artiste. The most notable include one at the Asia Model Festival Awards 2009, in which he won the Asia Special Award. Cheng, together with Sylvia Chang and Mike He, was appointed as an ambassador for World Vision in December 2009.

Music career
2009 was a quiet year for the television star, who spent the year busy with his theatre debut, Design for Living, starring opposite stage veterans Sylvia Chang and David Wang, under the directorship of Hong Kong stage director Edward Lam. The troupe made several sell-out shows in Hong Kong, China, Taiwan and Singapore. Cheng said that it has always been one of his goals to star in a stage play and was very honoured to have been able to star in the same production as Sylvia Chang. In the same year he also released his first EP, Sing a Song. Cheng is known by his friends in the industry as one who loves to sing. Album sales were fair and the EP topped certain charts in Taiwan but Cheng failed to convince music critics of the industry. Much to the dismay of his fans, Cheng did not star in any drama series in 2009.

In addition to his entertainment career, Cheng is completing his part-time university studies in tourism management at Hsing Wu College. As all males in Taiwan have to enlist for National Service, Cheng is due to enlist as soon as he completes his education. In 2010 Cheng represented Taiwan and performed at the 7th Asia Song Festival, organised by Korea Foundation for International Culture Exchange, at the Seoul Olympic Stadium.

Personal life
Joe Cheng is now discharged from military service in the second regiment of the Taiwan Coast Guard.

Filmography

Films
 What on Earth Have I Done Wrong?! (2007)
 Ripples of Desire (2012)
 Time Archive (2012)
 The Queens (2015)
 The Beloved (2015)

Television series

Variety Shows

Awards and nominations

Music videos
 2003 – 葉子" (Leaf) – The Rose OST by A-Sun
Bu Chao Bu Nao (不吵不鬧)- Landy 溫嵐
Ji Ta Shou (吉他手)- 陳綺貞
Gift – Jacky Cheung
Ye Zi/Leaf (叶子) – A Sun
E Zuo Ju (恶作剧)(It Started with a Kiss OST) – Wang Lan Yin
Bu Si Xin/Unwilling to Give Up (不死心) – Joe Cheng
Chang Yi Shou Ge/Sing a Song (唱一首歌)- Joe Cheng

Discography

Books
Yuan Wei Chang Kuai《元味暢快》(2005)
Always Smile 《籃球偶像事件簿》(2003)
My Color My Style 《我型我色——鄭元暢配色寶典》(2003)

References

External links

  Joe Cheng's site
  Joe Cheng@Avex Taiwan
  Profile at Catwalk Modeling Agency

1982 births
Living people
Male actors from Taichung
Taiwanese Mandopop singers
Taiwanese male stage actors
Taiwanese male television actors
Taiwanese idols
21st-century Taiwanese male singers
Musicians from Taichung
Participants in Chinese reality television series
Reality show winners
The Amazing Race contestants
Korean-language singers of Taiwan

redpajama_set_name: RedPajamaWikipedia


Paradise Guesthouse is located in Sihanoukville just a 5-minute walk from Phsar Leu Market. The guesthouse offers air-conditioned rooms with cable TV and private bathrooms. Wi-Fi is available for free. The rooms at Paradise Sihanoukville Guesthouse feature views of the city. The en suite bathroom includes hot and cold shower facilities and free toiletries. Guests can enjoy a massage at the guesthouse or rent a bicycle and explore the region. There are many local food options located around the guesthouse. There is also a cinema, a dive shop, several cafes, spas and souvenir shops around the guesthouse. The guesthouse is located just 3 km from Ochheuteal and Sokha Beach. Sihanoukville International Airport is a 30-minute drive away. Free private parking is available on site.


>>  ignored.  I cannot fgure out what "reserve the first line of a CIF2 file"
>>  code-page or UCS2 environment is supposed to do now.
>>  I would suggest actually writing the utility you have in mind.
>>  the PDB workflows, in Dectris detector software, etc.,. etc.
>>  loop and move forward?
>>  accept the failure of this effort, and start over.
>  >>freely available by the IUCr.
>>>>   checksum should be mandatory too.
>>>>   'stand-alone' non-UTF8 CIF2 files.
>>>>   should still carry its non-UTF8 declaration.
>>>>   that the encoding has been checked by a CIF-aware program.
>>>>   you that this would be acceptable.


Join Holy Spirit Church and School for our annual Golf Tournament at Cinnabar Hills Golf Club!
$40 Dinner & Auction only starting at 5:00 p.m.
Your player ticket will include green & cart fees, range balls, tee prizes, lunch, dinner and a live auction.
We welcome all golf skill levels, so you are guaranteed a fun day with friends in support of Holy Spirit School and Parish!
You don't golf? That's OK! Come out that evening to join us for the dinner and live auction. All are welcome! So please plan to join us for a great day of fun and community!
Sponsorships are available – please contact Joe Power at joe.power@zoomcopiers.com for details.
TO REGISTER AS A GOLFER OR TO SPONSOR online click HERE!
For more information, and to volunteer, please contact either Mike Butler at bultersan1@yahoo.com or Merry Reardon at mreardon@dsj.org.


text:
The Dinner Detective Murder Mystery Company is a nationwide theatrical production company based within the United States. The Dinner Detective Murder Mystery Company specializes in interactive murder mystery dinner theater entertainment in both public and private show environments.  Created in 2004 by Scott and Kelly O'Brien in Culver City, CA, The Dinner Detective employs actors from The Second City, Improv Olympic, Upright Citizens Brigade and many other improvisational theater schools across the country. They perform original scripts that involve heavy audience interaction as well as a four-course sit down dinner.

History
In 2004, Scott O'Brien, the company's founder and Executive Producer, along with his wife Kelly, started a company based around the idea of forming an improvisational and updated version of the old and dated murder mystery genre.  Assembling a small group of improv actors and rewriting their own original scripts based on actual cold cases, The Dinner Detective began performing their shows in 2004 at San Gennaro Restaurant in Culver City, CA.  In 2006, with the demand for their performances growing and in an effort to promote shows outside of Culver City, the Dinner Detective Murder Mystery opened its second location in Orange County, CA.  In 2007, The Dinner Detective opened its third location in Long Beach, CA.  In January 2008 the first franchise was opened in Boulder, CO.  Since 2009 over 80 locations have been opened nationwide.

Framework
The Dinner Detective has its corporate offices located in Colorado.  All of the individual locations hire and train local actors to perform in their public/private performances.  Through its original and proprietary franchised system, The Dinner Detective has established offices in over 80 cities throughout the United States.

Public shows
Public shows are mainly held inside hotels, but they can also take place in a variety of other venues including restaurants, banquet/conference facilities, and theatres. Shows last about 3 hours during which the audience experiences a multi-act interactive murder mystery while being served a plated three to four-course meal.

Private shows
The Dinner Detective also offers customized private parties for both large and small groups. Private shows are held at an establishment of the customer's choice or at one of the 80+ locations nationwide.  Typical events are corporate awards banquets, team building, employee recognition, birthdays, engagement parties, and family reunions.

See also
 List of dinner theaters

References

Dinner theatre
Companies based in Colorado
Theatre in the United States


text:
Farrakhan Rants About 'Satanic Jews' After Facebook Ban
In the wake of his ban from Facebook, Louis Farrakhan told a Catholic church Thursday night that he was there "to separate the good Jews from the Satanic Jews."
Speaking alongside radical activist Rev. Michael Pfleger at St. Sabina Church on Chicago's South Side, the Nation of Islam leader denied hating Jews but castigated those he said did not follow "God's word."
"I'm here to separate the good Jews from the Satanic Jews," Farrakhan said. "I do not hate Jewish people. Not one that is with me has ever committed a crime against the Jewish people, black people, white people. As long as you don't attack us, we won't bother you."

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: Set up a NTP server which can be queried globally I want to set up a server (hosted on aws/or a running system in some part of the world) as an NTP server that can be queried globally.
Currently, I have modified the ntp.conf file on the node to be made the server as server <public_ip_of_machine>. But the problem is, on using an NTP client if I try to query time from this server, or rather on using sudo ntpdate <ip_of_that_machine> it says no suitable server found.
However, if I replicate the same on my local network (the server, as well as the querying node, are all on the local network) then this works perfectly fine.
I think the problem might lie in the ntp.conf file. Do I need to put some specific restrict lines for this to work publically as well? And no I cannot list the server on public ntp pages. Is it at all possible?

redpajama_set_name: RedPajamaStackExchange


text:
WWorld
Thousands of Anti-Trump Protesters Take to Streets of U.S. Cities
byNews Week Me
CHICAGO/NEW YORK, Nov 10 – Demonstrators marched in cities across the United States on Wednesday to protest against Republican Donald Trump's surprise presidential election win, blasting his campaign rhetoric about immigrants, Muslims and other groups.
In New York, thousands filled streets in midtown Manhattan as they made their way to Trump Tower, Trump's gilded home on Fifth Avenue. Hundreds of others gathered at a Manhattan park and shouted "Not my president."
A demonstration of about 6,000 people blocked traffic in Oakland, California, police said. Protesters threw objects at police in riot gear, burned trash in the middle of an intersection, set off fireworks and smashed store front windows.
Police responded by throwing chemical irritants at the protesters, according to a Reuters witness.
In downtown Chicago, an estimated 1,800 people gathered outside the Trump International Hotel and Tower, chanting phrases like "No Trump! No KKK! No racist USA."
Chicago police closed roads in the area, impeding the demonstrators' path. There were no immediate reports of arrests or violence there.
"I'm just really terrified about what is happening in this country," said 22-year-old Adriana Rizzo in Chicago, who was holding a sign that read: "Enjoy your rights while you can."
In Los Angeles, protesters sat on the 101 Hollywood Freeway, blocking traffic as police in riot gear watched. A rally and march drew more than 5,000 people, many of whom were high school and college students, earlier in Los Angeles, local media reported.
In Seattle, police responded to a shooting with multiple victims near the scene of anti-Trump protests. Police said it was unrelated to the demonstrations.
Protesters railed against Trump's campaign pledge to build a wall along the border with Mexico to keep immigrants from entering the United States illegally.
Hundreds also gathered in Philadelphia, Boston and Portland, Oregon, on Wednesday evening. In Austin, the Texas capital, about 400 people marched through the streets, police said.
A representative of the Trump campaign did not respond immediately to requests for comment on the protests. Trump said in his victory speech he would be president for all Americans, saying: "It is time for us to come together as one united people."
Earlier this month, his campaign rejected the support of a Ku Klux Klan newspaper and said that "Mr. Trump and his campaign denounces hate in any form."
"DREAMERS" FEAR DEPORTATION
Earlier on Wednesday, some 1,500 students and teachers rallied in the courtyard of Berkeley High School, in a San Francisco Bay Area city known for its liberal politics, before marching toward the campus of the University of California, Berkeley.
Hundreds of high school and college students also walked out in protest in Seattle, Phoenix, Los Angeles and three other Bay Area cities – Oakland, Richmond and El Cerrito.
A predominantly Latino group of about 300 high school students walked out of classes on Wednesday in Los Angeles and marched to the steps of City Hall, where they held a brief but boisterous rally.
Chanting in Spanish "the people united will never be defeated," the group held signs with slogans such as "Not Supporting Racism, Not My President" and "Immigrants Make America Great."
Many of those students were members of the "Dreamers" generation, children whose parents entered the United States with them illegally, school officials said, and who fear deportation under a Trump administration.
"A child should not live in fear that they will be deported," said Stephanie Hipolito, one of the student organizers of the walkout. She said her parents were U.S. citizens.
There were no immediate reports of arrests or violence.
Wednesday's demonstrations followed a night of protests in the San Francisco area and elsewhere in the country in response to Trump's victory against heavily favored Democratic rival Hillary Clinton.
News Week Me
Traces of Daesh 'Mass Grave' Rot in Iraqi Spa Town
Kabul Welcomes Back National Geographic's Green-Eyed "Afghan Girl"
Iraq's Qayyara Oil Fields Won't Return to Production Before Mosul Retaken
BAGHDAD, Aug 30 – Iraq doesn't expect to resume production from the northern Qayyara oil region before the…
Kurdish Women Fighters Battle Daesh With Machineguns and Songs
SAMAQA, Iraq, Nov 4- When Daesh insurgents fired mortar bombs at Iranian Kurdish women fighters holding a desert position…
Copyright 2021© Newsweek Media Exchange. All rights reserved. Investment Finance & Business News


text:
Sometimes, some particular condition attributes cannot be used to
Posted on May 30, 2016 by micr4174
Sometimes, some particular condition attributes cannot be used to distinguish objects; they are redundant. The condition attributes excluding redundant attributes are called reduct in rough sets theory. A reduct is the essential part of an information table which can selleck product discern all objects discernible by the original table. The performance of the specified condition attributes can be described with two indicators:
accuracy of the approximation and quality of approximation. Accuracy of approximation represents the percentage of the associated objects definable with the specified condition attributes. It is defined as follows: αpX=cardA_XcardA¯X, (2) where cardrefers to cardinality. The value of accuracy ranges from 0 to 1. The closer to 1 is the accuracy, the more discernible is the condition attribute, that is, travel mode. It implies that the associated travel mode does exist unambiguously. On the other hand, quality of approximation represents what percentage of the universe is definable. Let X = X1, X2,…, Xn be a classification of U;
that is to say, Xi∩Xj = ∅, ∀i, j ≤ n, i ≠ j and i=1nXi = U. Xi is called class of X. Quality of approximation of classification X by a set of attributes can be defined as follows: γpX=∑i=1rcardA_XicardU. (3) The value of quality ranges from 0 to 1. The closer to 1 is the quality, the more objects of the universe clearly belong to a single class of X. It implies that all travel modes can be clearly identified. To recognize further details of mode choices, rules need to be extracted. Using reduced information table (without redundant attributes), the rules could be found through determining the decision attributes value based on condition attributes values. Therefore, the rules are presented in an "IF condition(s) THEN decision(s)" format. If the condition(s) in the IF part matches with the given fact(s), the decision(s) in the THEN part will be performed. Unlike mathematical functions or statistical models in traditional travel demand forecasting analysis, decision rules induced from a set of raw data can capture and represent both numeric and
nonnumeric variables. In addition, the modular nature of decision rules makes it easy for researchers to insert new decisions rules or to modify/delete existing decision rules without affecting the overall system. Once a set of rules have been derived, it is then that the training stage of the Drug_discovery knowledge discovery finishes and the rules are then tested. 4.2. Theory of Testing The testing stage is relatively straight forward and involves the application of rules to a previously unseen set of data in order to predict mode choice. Fortunately the actual mode choice is known so it is therefore possible to evaluate the predictive ability. This information is usually presented in a confusion matrix [26] which contains the actual mode choices as rows and the predicted mode choices as columns.
21 We aim to establish the most up to date description of the
21 We aim to establish the most up to date description of the order innovativeness of new drugs launched in the UK, and to understand whether the recent increase in drug launches represents increasing numbers of highly innovative new drugs being made available, or whether the apparent recovery in launch volumes is due to increasing numbers of drugs of limited additional therapeutic value. We adopted the criteria proposed by Aronson et al1 to define the degree of innovation based on an assessment of clinical usefulness and the nature of the innovation (table 1). Table 1 Criteria for determining clinical
usefulness and nature of pharmaceutical innovation, adapted from Aronson et al1 and Ferner et al10 Methods Data collection and definition of new drugs We obtained data on the numbers and characteristics of new drugs (NCEs and new biological agents) launched in
the UK each year from relevant editions of the British National Formulary (BNF). The BNF lists all preparations available for prescribing and/or dispensing in the UK, including prescription only and over-the-counter medicines. Information on the active ingredient and BNF chapter heading (organised into broad therapeutic areas) for every item in the 'new preparations' section of each BNF from edition 41 in 2001 to edition 64 in 2012 was obtained and entered onto a spreadsheet. The BNF also includes non-drug products (nutraceutical and medical foods, natural products, devices and diagnostic products), new salts and esters of existing chemical compounds, and generic or biosimilar preparations; these products
were excluded to leave only new drugs (full details given in online supplementary file 1).19 In addition, active and passive immunisations were excluded from the data as these typically follow different development and National Health Service (NHS) market access pathways to other drugs. Commercial pharmaceutical databases (Pharmaprojects, Informa Healthcare; and Adis R&D Insight, Springer International Publishing) were also used to determine whether a substance was a new drug at the date of UK launch. Different dosages of the same product were counted only once; different formulations of the same product, Entinostat for example, oral tablet and intramuscular injection, were counted once if they contained the same active ingredients, and multiple times if they contained different active ingredients. Different indications for the same product were counted once. Determination of innovation level The criteria proposed by Aronson et al1 (table 1) were used to determine the degree of innovation at the time of launch for all new drugs identified as entering the UK market between 2001 and 2012 (inclusive). Clinical usefulness and the process through which the innovation arose (nature of the innovation) were determined by simple searches of online sources, including the NHS Evidence web portal (http://www.evidence.nhs.
67, R2=0 44, y=1 03×year−2062 0 (p=0 051)) and total new drugs (r
67, R2=0.44, y=1.03×year−2062.0 (p=0.051)) and total new drugs (r=0.81, R2=0.65, y=1.20×year−2385.5 (p=0.009)). In contrast, no linear trends were apparent in moderately innovative or highly innovative new drugs for the purchase ABT-869 same time period (r=0.19 and 0.04, respectively). Table 2 Numbers of new drug launches in the UK and degree of innovativeness by BNF chapter heading, 2001–2012 Figure 1 Numbers of new drug launches in the UK and degree of innovativeness by year, 2001–2012. Considering BNF chapter headings, 6 of the 15 broad therapeutic areas represented over three-quarters of all new drugs, namely malignant disease and immunosuppression; infections; cardiovascular system; endocrine system; central nervous
system; and nutrition and blood (table 2). Each of these provided at least 9% of all new drugs during the study time period, with malignant disease and immunosuppression making up
19.7% of the total. A statistically significantly greater proportion of drugs were coded as highly innovative in two broad therapeutic areas (malignant disease and immunosuppression (p=0.0003, one-tailed χ2 test); and skin (p=0.028)) when compared with the total proportion coded as highly innovative (table 2). In addition, almost 40% of drugs in the nutrition and blood chapter were coded as highly innovative, though the difference from the overall proportion was not statistically significant (p=0.062). In contrast, a statistically significantly greater proportion of drugs were coded as slightly innovative in the chapters for eye disease (p=0.013) and immunological products and vaccines (p=0.014). In addition, 80% of new drugs in the obstetrics, gynaecology and urinary-tract disorders chapter, and all new drugs in the ear, nose and oropharynx
chapters, were coded as slightly innovative, though these results were not statistically significantly different from the overall proportion (p=0.59 and 0.10, respectively), and the latter group included only two drugs. Discussion This is the most up to date study that considers the innovativeness of new drug introductions into the UK. The BNF includes all medicinal products available for dispensing in the UK, and the printed editions were updated every 6 months, providing an accurate and reliable account of Drug_discovery new drugs launched in the UK each year. We identified an upward linear trend in the annual numbers of slightly innovative new drugs launched in the UK since 2004, which aligns closely with the recovery in total numbers of new drug launches seen since that time.19 No apparent similar increase in moderately innovative or highly innovative new drugs was observed. Just six broad therapeutic areas accounted for over three-quarters of new drug introductions, and of these, drugs for malignant disease and immunosuppression, and nutrition and blood disorders were also more likely to be categorised as highly innovative.
Patient claims data were matched to the hospitals where each pati
Patient claims data were matched to the hospitals where each patient was admitted.
Hospital-level data included fty720 PP2a characteristics of the hospital, such as hospital type (specialty, tertiary, large, small), number of beds (in 100 bed increments), specialists per 100 beds, nurses per 100 beds, hospital location (metropolitan if located in cities with a population of more than one million), teaching status and bed occupancy rate. According to the Korean Hospital Association, Korean hospitals are categorised into three groupings based on bed size: (1) hospitals with over 1000 beds: tertiary research university hospitals, (2) hospitals with 300–1000 beds: mid-sized general hospitals and (3) hospitals with 100–300 beds: small general hospitals. The specialty hospitals and the small general hospitals in our study both fell within category 3 (small general hospitals).21 The hospital level data were obtained from the Agency for Health Insurance Review and Assessment Services. In order to investigate the post
policy designation effect, we included the interaction term of type of hospital and year, which we named designation effect. We also included data envelopment analysis (DEA) using efficiency as the dummy variable (1=efficient, 0=non-efficient) to determine whether hospitals were operated efficiently using a conventional technical efficiency measuring technique.22 It is derived from microeconomics methodology where input and output combinations are depicted
using a production function to measure the efficiency of multiple decision-making units (in this case hospitals) when the production process presents a structure of multiple inputs and outputs.22 Input variables included number of beds, surgical beds, recovery beds, specialists, residents, nurses, physical therapists and pharmacists; and positron emission tomography, CT and MRI units of each hospital. Output variables included total number of inpatient cases and AV-951 sum of charges in 2011 and 2012 study periods for each hospital. Hospital-level statistics were collected based on their first quarter of 2012 status, which was the only available data set at the time of this study. Analytical approach Mean and SD were analysed for continuous variables; frequency and per cent were analysed for categorical variables. Univariate analysis of inpatient charges, LOS, readmission within 30 days of discharge and mortality within 30 days of admission was performed to investigate the unadjusted effects of hospital types on these measures. Analysis of variance and χ2 tests were performed for identification of group differences.
The six exercise sessions presented within the other two DVDs are
The six exercise sessions presented within the other two DVDs are comprised of an orchestrated sequencing of progressions (ie, beginning with simpler, more basic AZD9291 movements, and then building on exercises learned to ultimately engage in more complex movements). Delivering the exercise programme in such a manner helps to ensure that new challenges are built on a previous foundation and to help minimise the risk of injury. Participants will be instructed to inform research staff of any adverse events that might occur as a result of participation. This information will be documented, reported to the Institutional Review Board, and discussed in future publications regarding study outcomes. Furthermore, each
of the exercises presented within the DVDs will include two additional versions that vary in difficulty to make the exercises more attainable or challenging for individuals of varying functional capabilities and to further reduce the risk of injury. Using the standing military press exercise as an example, the exercise leader will instruct participants to stand straight with their feet in a staggered position while placing the centre of an exercise band directly between the front foot and the floor. She will then instruct them to grab the handles of the bands and position their hands so that the palms face forward/outward (ie,
towards the direction of the TV for those doing the exercise at home). Next, participants will be told to form a 'goal post' type position with their arms (ie, elbows in line with shoulders and forearms perpendicular with the ground). From this starting position, participants will be told to extend their elbows and press/raise their hands straight up over their head in a slow and controlled manner and up to the point where their thumbs almost touch. They will then be instructed to slowly lower the band back to starting position to complete one repetition. To modify the military
press, participants will be encouraged to use light hand weights as opposed to standing on an exercise band, as this will provide less resistance and greater range of motion. To make the exercise more challenging, participants will be instructed to stand with both feet evenly spaced on the band while performing the movement, which will considerably increase the level of resistance. Participants in the FlexToBa group will be instructed to exercise with the DVDs on a regular basis (ie, Carfilzomib every other day or at least three times per week) and to complete and mail in the exercise logs on a monthly basis via previously provided self-addressed stamped envelopes. These logs will be collected and entered by select, unblinded research personnel, who will also be responsible for generating and mailing personalised programme feedback to the corresponding participants for each of the six monthly exercise sessions.
Further high-quality prospective clinical trials are urgently nee
Further high-quality prospective clinical trials are urgently needed in demonstrating the safety, benefits
and optimal modes of deprescribing, especially in relation to multimorbid older people.61 64 The fog of polypharmacy else clouds a prescriber's capacity and confidence to identify PIMs which, to be overcome, requires complete and accurate clinical information and decision support. Professional organisations and colleges have an important role in encouraging the necessary cultural and attitudinal shifts towards 'less can be more' in appropriate patients. The push for guideline adherence and intensification of therapy needs to be counterbalanced by the view that judicious reduction, discontinuation or non-initiation of medication, in the context of shared decision-making and agreed care goals, is an affirmation of highest quality, individualised care.65 This view needs to be embraced in the education and training of all health professionals, not just doctors, who influence the prescribing process. Prescribers are making decisions in the face of immense clinical and health system complexity. Appropriate deprescribing needs to be regarded as equally important and achievable as appropriate initiation of new medications. Understanding how
prescribers perceive and react to prescribing and deprescribing contexts is the first step to designing policy initiatives and health system reforms that will minimise inappropriate overprescribing. Supplementary Material Author's manuscript: Click here to view.(2.4M, pdf) Reviewer comments: Click here to view.(147K, pdf) Acknowledgments The authors thank the University of Queensland librarians Mr Lars Eriksson and Ms Jill McTaggart for their assistance in developing the search strategy
and Ms Debra Rowett for her invaluable insights when scoping the search and developing the manuscript. Footnotes Contributors: IS conceived the paper, the scope of which was refined by all authors. KA searched the literature, led AV-951 the data analysis and drafted the manuscript. IS and DS read articles and assessed the data analysis for comprehensiveness and reliability. IS, DS and CF provided critical comments and contributed to the interpretation of the analysed results and framework development. All authors read, revised and accepted the final draft. Funding: KA and IS are funded through a National Health and Medical Research Council grant under the Centre of Research Excellence Quality & Safety in Integrated Primary/Secondary Care (Grant ID, GNT1001157). Competing interests: KA received a speaker honorarium for an Australian Association of Consultant Pharmacy presentation. DS reports personal fees from the National Prescribing Service, outside the submitted work.
Theoretical framework The study will take a social constructionis
Theoretical framework The study will take a social constructionist approach to understand patients' meaning-making in relation to non-emergency cardiac symptoms.46 This approach starts from the view that individuals and groups construct or create their realities, influenced
by multiple factors including sex, culture, www.selleckchem.com/products/ABT-888.html ethnicity and expected social behaviours. It also considers the consequences of these social constructions, for example, a belief that women do not get heart disease is likely to impact on help-seeking. Semistructured interviews using an interview guide will be used to ensure we uncover the meaning patients attribute to their circumstances, and cover topics considered important to the project. Sampling Maximum variation sampling will be used in order to
capture a wide range of perspectives within the phenomena being studied.47 The sampling dimensions are sex, age and ethnicity to ensure the recruitment of a heterogeneous sample and will include at least: Four male patients >50 years of age and include a mixture of white and ethnic minority participants. Four female patients >60 years of age and include a mixture of ethnic minority and white participants. Four male patients <50 years of age and will include a mixture of ethnic minority and white participants. Four female patients <60 years of age and include a mixture of ethnic minority and white participants. The sample will be drawn from referrals to the rapid access chest pain clinic (RACPC), which specialises in the assessment of non-emergency cardiac symptoms (stable angina), at Queen Mary's Hospital, Roehampton. The RACPC operates on Mondays and Thursdays and sees over 80 patients a month. The service covers a large and highly diverse catchment area, making
it the ideal centre to capture the maximum variation required. Recruitment Recruitment will last approximately 12 months, starting February 2014 and continue until data saturation, that is, no new themes important to the project are being elaborated on. It is envisaged a sample of 20–30 participants will be recruited. Although this sample might be considered Entinostat too small for quantitative research, in qualitative research it is considered that this sample is large enough to reach saturation of concepts. Indeed, Baker and Edwards expert discussion paper suggests saturation can be achieved with as low as 12 participants with the average being 30 participants.48 Similar studies in gender comparison work have shown concept density (saturation) at around 20 participants.19 43 Referrals, medical records and the Patient Administration System (PAS) system will be used to identify candidates who meet the inclusion/exclusion criteria, as detailed in table 1.
48 Supplementary Material Reviewer comments: Click here to view (
48 Supplementary Material Reviewer comments: Click here to view.(6.9K, pdf) Acknowledgments The authors thank Susie Bernier for the translation and Isabelle
Gaumond for the final revision of the manuscript. Footnotes Contributors: concerning CH, M-CC and MC initiated the project and designed the study. AB (implementation analysis), EMC (health literacy), M-FD (statistical analysis), MF (multimorbidity), TF (case management), CL (poverty), JM (healthcare database), PP (participatory research), PR (mental healthcare) and CR (case study) provided specific expertise. All authors contributed to the redaction and approved the final version of the manuscript. Funding: This work is supported by the Canadian Institutes of Health Research (CIHR) grant number 318771. Competing interests: None. Ethics approval: The research protocol was approved by the Ethics Research Boards of the four HSSCs involved (Chicoutimi, Jonquière, Alma and La Baie). Provenance and peer review: Not commissioned; internally peer reviewed.
Attention deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder and affects 3–5% of children and young people.1 The core symptoms of ADHD include poor attention,
hyperactivity and impulsivity. National Institute for Health and Care Excellence (NICE)1 guidelines provide a blueprint for the diagnosis and management of ADHD in England and Wales and indicate the need for young people with ADHD to have access to the best evidence-based care in order to fulfil their potential and prevent poor outcome. However, in practice, delivery and quality of care is ad hoc, with little consistency in assessment,
diagnosis or management.2 ADHD frequently coexists with other neurodevelopmental and psychiatric disorders and is a risk factor for major educational, social and occupational impairment, placing a huge burden on the National Health Service (NHS), social care and criminal justice systems. There has been a rapid growth in diagnosis over the past 30 years with the number of children recognised and treated for ADHD in the UK increasing almost 10-fold from the early 1980s1 and spending Entinostat on medication for ADHD increasing sevenfold between 1998 and 2005.3 The cost of initial specialist assessment for ADHD is estimated at £23 million annually in England and Wales4 and drug costs for ADHD in England during 2012 was expected to exceed £78 million3 while indirect costs to families include parental mental ill health, time off work and loss of earnings are even higher.5 Increasing recognition of ADHD as a lifespan condition is placing a new demand on the NHS to provide diagnostic and treatment services for children, adolescents and adults, exposing serious limitations in existing methods of assessment and management. There is no single test, or biomarker used to diagnose the disorder.
74) The grades were totalled to create a composite score: the lo
74). The grades were totalled to create a composite score: the lower the score, the better the knowledge. The scores were dichotomised by the median score to those who demonstrated reasonable knowledge and those whose knowledge was insufficient. In order to enough measure negative affective status, the ULCA Loneliness Scale21 and the Sexual Sensation Seeking Scale22 were used.
Statistical methods Analyses were performed using χ2 or Fisher's exact tests for associating the categorical variables. Continuous variables were analysed by Student's t test or by the Mann–Whitney non-parametric test for variables distributed abnormally. Logistic analysis identifying variables predicting high-risk sexual behaviour or excessive anaerobic training included variables with p<0.05 after assessment for collinearity and normal distribution
in backwards fashion. The model generated ORs and 95% CIs. Confounding between IAT, sexual risk and sexual orientation, as well as interaction between sexual orientation and IAT, among high-risk participants were assessed using 2-by-2 tables. Analysis was conducted using the SPSS V.17.0 package for Windows software. The study was approved by the E Wolfson Medical Centre Institutional Review Board (WOMC-0058-09). Results Of approximately 600 men who were approached in five gyms in central Tel Aviv, 379 who were older than 18 years of age and reported more than one act of sexual intercourse in the preceding 6 months completed the questionnaire. Of these 379 men, 182 (48%) were MSM (154 reported sex exclusively with men and 28 engaged in sex with both men
and women), while 197 (52%) were heterosexual. The mean±SD age of all the participants was 31.9±6 (range 18–60) years. MSM versus heterosexual men In comparison with heterosexual men, MSM were more likely to be Israeli-born, have lower BMI, have followed a dietary regimen, and used protein supplement powders or anabolic steroids (table 1). They also reported a greater number of casual sex partners and more commonly used drugs before or during sex. MSM demonstrated a Anacetrapib stronger desire to become muscular (OR for preferring to be muscular than rich 3.0, 95% CI 1.9 to 4.9, p=0.01), and a greater percentage reported performing IAT than heterosexual men. Body shaping and improving self-confidence were the main reasons of MSM for training, while losing weight and improving health were more predominant reasons among heterosexual men. The threat of HIV perceived by MSM was lower than that perceived by heterosexual men, yet MSM considered themselves to be at higher risk of acquiring HIV/STI and had higher sexual desire scores than heterosexual men.
There was also a correlation between traffic volume within 100 m
Posted on May 9, 2016 by micr4174
There was also a correlation between traffic volume within 100 m of a residence and a modest increase in the rate of lung cancer (HR 1.09 (CI 0.99 to 1.21)). No similar correlation was found with NOx air pollution. This suggests that long-term exposure to higher levels of particulate matter air pollution may increase the incidence of lung cancer in a
population. Another study published selleck catalog in the USA in 2004 looked at the long-term effect of exposure to particulate matter air pollution and the mortality attributed to different cardiovascular and respiratory diseases in different areas of the USA.4 A good correlation was found between the degree of long-term exposure to Pm air pollution and increases in mortality from cardiovascular diseases, including heart failure.
Interestingly, this was not found to be the case for most respiratory diseases. There was also an element of the study that looked at the effect of a person's smoking status on the mortality statistics. This found, as expected, a strong link between mortality and smoking. However, it also found that air pollution contributed additional cardiovascular mortality risk on top of that attributed to smoking. This was at least an additive, if not a synergistic effect. Methods Study data In order to carry out this project, data were collected on the geographical distribution of air pollution within Warwickshire. These data included information about each of four individual components of air pollution (NOx, sulfur dioxide, particulate matter and benzene), which could then be united into a combined index (all of the contributions added together). A single recorded level from 2010 of each air pollutant for each ward was used in the study. This was then compared to collected data about: The geographical distribution of home addresses of patients who were admitted to hospital because of heart failure or a complication of heart failure. Hospital admission rate in an area due to heart failure was used as a proxy indicator for the level of heart
failure morbidity within that area. The geographical distribution of home addresses of patients who died from heart failure, or whose death was contributed to by heart failure. These data were collected by the Warwickshire Anacetrapib Observatory, which is part of the Warwickshire County Council in charge of collecting and handling statistics relating to the county. Mortality data for the analysis were supplied via the Warwickshire Public Health Intelligence Team and was sourced from the Public Health Mortality Files, Office for National Statistics. Hospital admissions data were accessed via the Ventris Business Intelligence System, Arden Commissioning Support Unit. Ward level population data were obtained from the 2011 census. Warwickshire is divided into 105 wards. Data from all of the 105 current Warwickshire County wards were collected.


Alexander Stefaniak is assistant professor of musicology at Washington University in St. Louis. His research centers on 19th-century music: specifically, instrumental virtuosity, Romantic aesthetics, music criticism, and the Schumann circle. His first book, Schumann's Virtuosity: Composition, Criticism, and Performance in Nineteenth-Century Germany, was published 2016 by Indiana University Press. Stefaniak has presented his work at national meetings of the American Musicological Society, at the International Liszt Congress, and at the North American Conference on Nineteenth-Century Music. He received his PhD in 2012 from the Eastman School of Music and joined the faculty of Washington University in Saint Louis that year.
For readers interested in concert pianists, Van Cliburn and his story enrich our understanding of how classical musicians developed their careers against the backdrop of the Cold War. For those drawn to this book more out of interest in political history, Nigel Cliff shows that musicians' stories can give us perspective on the private and public faces of this conflict.


2 Year Blogiversary And The Best Giveaway Ever!
Two years ago today, I started Never Not Knitting. Little did I know back then what this blog would turn into or what fun it would bring to my life.
In honor of my two year "blogiversary" I would like to extend a thank you. Thank you to all of you who regularly visit me, who comment on my posts, who support my blog sponsors. It's been such a pleasure for me to meet so many fantastic knitters from all over the world.
In order to get to know my readers better, I would like to announce 2 new drawings!
All you have to do in order to enter drawing #1 is to leave a comment under this blog post. Please tell me in your comment how you found the Never Not Knitting blog and how long you've been a reader. That's it!
The prize for drawing #1 is going to be a compilation of NeverNotKnitting patterns, yarn, and other sweet treats!
I know that I have a lot of readers from all around the world. I would love to put some faces with the names. Entering drawing #2 is going to require a little more effort than drawing #1 but, believe me, it's worth it... the prize is going to be huge...huge...HUGE!
The prize for drawing #2 is going to be a box of goodies including designer knitting patterns, skeins of yarn, a gift certificate, buttons, a row counter, a tee-shirt, sweet treats, the entire Never Not Knitting pattern collection, and knitting notions bags.
This prize and contributor list may be added to as time goes on!!
What you need to do to enter drawing #2 is to email me a picture of yourself in your favorite knitting location. You'll need to be holding a sign that says "I am Never Not Knitting at" and then put where your favorite place to knit is (like the name of your local yarn shop, etc). Also put where you are from...State/Province and Country is great!
When the drawing is over, I will be compiling all of the photos into a large collage to be shared in a future blog post on NeverNotKnitting.com. It'll be so fun for me to see pictures of all of you!
You can enter both drawings #1 and #2, but only enter each drawing once.
Drawings both end at 11:59PM PST, December 15, 2009. I will randomly choose a blog comment for drawing #1 and an emailed picture for drawing #2 to determine the winners. I will announce the winners on the blog on December 16, 2009.
Thank you so much for sharing my knitting adventures with me over these past two years!
Please Join The Cedar Leaf Shawlette Knit-a-long!
*Don't forget to enter this episode's yarn drawing!
One Planet Yarn and Fiber is offering free US shipping to all NeverNotKnitting podcast listeners and blog readers until Dec. 15th, 2009.
Be sure to enter the promotional code "NNKship" in the checkout process!
Congratulations to Episode 27's drawing winner, Anita! She won a skein of Malabrigo worsted!
Click here to download the MP3 of Episode 28.
I am so happy to announce that my Cedar Leaf Shawlette pattern is now available for purchase.
This is a tiny crescent shaped shawlette that drapes beautifully around your shoulders and looks absolutely stunning wrapped around your neck as a scarf.
This design marries my two favorite things in the whole world. The color green and knitted leaves. I couldn't love it more!
The curved stockinette st body is created through the use of short rows, and the beautiful leafy border is knit onto the body of the shawlette after its completed.
I found the construction to be very easy. No seaming. No picked up stitches.
As you can see, the shawlette is quite versatile. It can be successfully worn several different ways.
I wore mine out for the first time today. It was wonderfully soft and it added a vibrant accent to my winter outfit. I really want to wear it every day. Would people think I was weird?
Length: 54 inches from end to end.
Width: measures approx 8 inches at widest point of center including leaf border.
20 sts/36 rows = 4" in Stockinette stitch on size 7 needles or size needed to obtain gauge.
This pattern includes instructions for short row shaping. I found a couple of good instructional videos highlighting this method here and here.
You can also find a great video showing how to hide the wraps on the purl side here.
Cedar Leaf Knit Kits are available here through One Planet Yarn and Fiber.
I really hope that you enjoy knitting up a Cedar Leaf Shawlette of your very own. Im going to be starting my second one shortly and invite you all to knit-a-long with me here on Ravelry.
Pattern is now available in French! Click here to purchase the french translation.
Pattern is also now available in Dutch! Click here to purchase the dutch translation.
I have a new design on the needles... and I am loving every stitch.
Check back soon for more progress pictures!
Dancing Ewe Yarns is offering all NeverNotKnitting blog readers and podcast listeners 10% of the entire selection of Malabrigo yarns through December 1, 2009.
Just enter in the special code "NNK1" in the checkout process!
Congratulations to commenter "3 Dogs and a Chinchilla" the winner of last episodes podcast drawing to win a skein of O-wool balance from Dancing Ewe Yarns!
Click here to download the MP3 of Episode 27.


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Good vs Bad Fat - pt 2 - What's good or bad?
Not all fats are bad, that's why it's good to know the difference between "good" and "bad" fats. Bad fats are the ones that are very hard for your body to break down and convert into energy. Good fats are very easy for your body to change into energy.
Fats, under a microscope, come either a long chain or a clumpy-like grouping. The quality of your fat depends on its shape, in the chemistry-type way, from what I can remember my nutrition teacher saying.
Polyunsaturated is the best fat in the converts-to-energy-real-fast type way. Monounsaturated is good-to-okay. Saturated fat is where you get yourself into trouble, as far as zipping up the jeans or avoiding the aspirin regimen, because they're not as easy for your body to convert to energy. And Trans Fats were invented by Satan, pretty much. They stay in you for aeons.
A more in depth definiton of the fats are in the next entry.