Mammaglobin A is a protein that belongs to the secretoglobin superfamily. It has highly specific expression in cells from most breast cancers and may be used to detect circulating or disseminated tumor cells. In addition, mammaglobin A is currently under investigation as a potential therapeutic target for immune therapies that target breast cancer. The present review will highlight our current understanding of mammaglobin A at the genetic and protein level and its potential clinical applications. Characteristics of breast cancer and methods used to isolate and detect circulating tumor cells will also be presented.
Keywords: MAMMAGLOBIN A; BREAST CANCER; TUMOR MARKER; CIRCULATING TUMOR CELLS; Oncología; Medicina Clínica; CIENCIAS MÉDICAS Y DE LA SALUD.
Hepatocellular carcinoma (HCC) is the fifth most frequent cancer worldwide. Sorafenib is the only drug available that improves the overall survival of HCC patients. P-glycoprotein (P-gp), Multidrug resistance-associated proteins 2 and 3 (MRP2 and 3) and Breast cancer resistance protein (BCRP) are efflux pumps that play a key role in cancer chemoresistance. Their modulation by dietary compounds may affect the intracellular accumulation and therapeutic efficacy of drugs that are substrates of these transporters. Genistein (GNT) is a phytoestrogen abundant in soybean that exerts its genomic effects through Estrogen-Receptors and Pregnane-X-Receptor (PXR), which are involved in the regulation of the above mentioned transporters. We evaluated the effect of GNT on the expression and activity of P-gp, MRP2, MRP3 and BCRP in HCC-derived HepG2 cells. GNT (at 1.0 and 10 µM) increased P-gp and MRP2 protein expression and activity, correlating well with an increased resistance to sorafenib cytotoxicity as detected by the methylthiazole tetrazolium (MTT) assay. GNT induced P-gp and MRP2 mRNA expression at 10 but not at 1.0 µM concentration suggesting a different pattern of regulation depending on the concentration. Induction of both transporters by 1.0 µM GNT was prevented by cycloheximide, suggesting translational regulation. Downregulation of expression of the miR-379 by GNT could be associated with translational regulation of MRP2. Silencing of PXR abolished P-gp induction by GNT (at 1.0 and 10 µM) and MRP2 induction by GNT (only at 10 µM), suggesting partial mediation of GNT effects by PXR. Taken together, the data suggest the possibility of nutrient-drug interactions leading to enhanced chemoresistance in HCC when GNT is ingested with soy rich diets or dietary supplements.
Keywords: MRP; GENISTEIN; HCC; SORAFENIB; Bioquímica y Biología Molecular; Ciencias Biológicas; CIENCIAS NATURALES Y EXACTAS.
Radiotherapy and chemotherapy cause genotoxic side effects that are highly variable among patients. In this study, we evaluated DNA integrity using the comet assay in peripheral blood lymphocytes from breast cancer patients before ("pre-treatment patients"; n = 47) and after ("post-treatment patients"; n = 24) radiotherapy and/or chemotherapy treatment and from healthy donors (n = 15). Comet evaluation was made by visual (types 0−4) and digital (percentage of DNA remaining in the comet head = % head DNA) analysis. The association between the level of DNA damage and cancer prognostic factors was assessed. The treatments caused a significant increase in DNA damage registered by both visual (p < 0.001) and digital (p < 0.001) analyses. No significant associations between the level of DNA damage in pre-treatment patients and cancer prognostic factors were found. A significant correlation between the comet results from each patient before and after treatment (r = 0.64, p = 0.001) was observed. The % head DNA in post-treatment samples from patients with a high level of DNA damage before treatment (30.3 ± 3.1%, p < 0.01) was lower than in post-treatment samples from patients with a low-to-medium level of DNA damage before therapy (49.2 ± 4.4%). These results support the usefulness of the comet assay as a sensitive technique to evaluate basal DNA status and DNA damage caused by cancer treatments. The comet assay could contribute to treatment decisions, especially by taking into account the patient's basal DNA damage before therapy.
Keywords: comet assay; genotoxic damage; peripheral blood lymphocytes; prognostic factors; Oncología; Medicina Clínica; CIENCIAS MÉDICAS Y DE LA SALUD.


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ReBrand: East Kilbride FC
Posted on 4 June 2019 22 August 2019 Posted in graphicTagged badge, bird, crest, East Kilbride, East Kilbride FC, East Kilbride Football Club, EK, Europe, football, Kilby, Lanarkshire, Latin, LFL, logo, Lowland Football League, Lowlands, oystercatcher, rebrand, redesign, Scotland, Scottish Lowland Football League, SLFL, South Lanarkshire, sport, texture, The Kilby, UK, United Kingdom1 Comment
The original East Kilbride Football Club was established in 1871, making it one of the earliest association football clubs in Scotland, after Queen's Park (1867), Kilmarnock (1869) and Stranraer (1870). East Kilbride's early years, like many football clubs at that time, were precarious, with the club folding and reforming on several occasions. Ultimately, the club folded for good after about a decade and the town of East Kilbride went unrepresented at the senior level for more than a century.
In 2010, the local junior sides Stewartfield FC and Jackton Boys Club merged to form a new club, taking the defunct East Kilbride FC name. For the 2012/13 season, East Kilbride competed in the South of Scotland Football League before becoming members of the Lowland Football League in its inaugural season the following year. Since joining the league, East Kilbride have proven very formidable, coming second in 2014/15, winning the league in 2016/17, coming second again in 2017/18 before securing their second league championship in 2018/19.
Having won the Lowland League on two occasions, East Kilbride were eligible to compete in a play-off against the Highland Football League champions for a chance at gaining a place in the Scottish Professional Football League. In 2017, East Kilbride beat Buckie Thistle with an aggregate score of 4-3 in order to advance to the League Two play-offs against last-place Cowdenbeath. The first leg, which took place at East Kilbride's home ground of K-Park, ended with no score. The second leg ended 1-1 after extra time, forcing a penalty shootout to decide which would compete in the SPFL the following season. The shootout proved heart-breaking for East Kilbride, who lost 5-3.
The club's second chance at promotion to the SPFL came following their latest league championship (2018/19), though the Kilby lost to the Highland League champions, Cove Rangers with an aggregate score of 5-1 (Cove went on to gain promotion to the SPFL with a 7-0 aggregate victory over Berwick Rangers).
The club's current badge is attempting to do a lot. It draws its colours from the 1871 club's colours of gold and dark blue and employs a number of local symbols. The use of the oystercatcher, the cross and the colour red represent St Brigid of Kildare, after whom 'Kilbride' is named. The current badge also features the date of the original club's founding as well as the Latin motto, a priori, meaning 'from the earlier', which is yet another reference to the original club.
While I appreciate the symbolism of the current badge, I feel it tries to do too much in its current form. In order to comply with an ancient heraldic Scottish law, my redesigned badge takes the form of a roundel. The central image is an oystercatcher atop a football. The outer circle includes the club's name, the Latin motto and the years of the founding of the original and current East Kilbride FC.
For the home kit redesign, I have gone with the traditional East Kilbride harlequin-style shirt of gold and dark blue and for the away kit I have made use of the current away colour scheme of red and white, though instead of opting for harlequin-style featured in the current away kit, I have gone with bold, thick hoops.
ReBrand: Lossiemouth FC
Posted on 29 January 2019 29 July 2019 Posted in graphicTagged badge, Coasters, Covesea Lighthouse, crest, Europe, football, HFL, Highland Football League, Highlands, Latin, lighthouse, logo, Lossie, Lossiemouth, Lossiemouth FC, Lossiemouth Football Club, Moray, Morayshire, rebrand, redesign, Scotland, Scottish Highland Football League, SHFL, sport, texture, The Coasters, UK, United KingdomLeave a comment
Lossiemouth Football Club was established in 1945 and joined the Highland Football League the following year, where it has played ever since.
Despite competing in the Highland League for nearly three-quarters of a century, Lossiemouth has never won the league, one of only seven HFL clubs to have never achieved the honour (with the remaining six having joined the league much later: Fort William, who joined in 1985, Wick Academy, who joined in 1994, Inverurie Loco Works, who joined in 2001 and Formartine United, Strathspey Thistle and Turriff United, who joined in 2009).
The Coasters have a longstanding rivalry with their neighbours to the south, Elgin City, with City dominating most of their meetings until the early 1990s. The club's first honour came in 1962, when they won the Highland League Cup. They would not add to their silverware until winning the 1994/95 North of Scotland Cup. They would repeat this victory the following two season and again in 2001 and 2003. The 1996/97 season proved to be Lossiemouth's most successful, winning both the North of Scotland Cup as well as their second Highland League Cup and finishing the season fourth in the league table, being edged out of the third spot by Peterhead on goal difference alone.
The current Lossiemouth badge features a lighthouse superimposed over a stylised football in red and white, the club's colours. The lighthouse is a representation of Covesea Skerries Lighthouse, completed in 1846 and located very near the town of Lossiemouth. For my redesign, I wanted to keep the lighthouse image, but decided to depict a version of the lighthouse more true to its actual appearance. As lighthouses function primarily at night and in poor visibility, I depicted a night's sky in black and a representation of Ursa Major, suggesting the northerly position of Lossiemouth (which sits at the northern tip of Morayshire). I also included the Latin motto PER NOCTEM LUX (which can be translated into English as something like 'the light through the night'), found on a Lossiemouth and Branderburgh burgh seal from the late nineteenth century. The motto is a play on the town's patron saint, St Gerardine (or St Gervadius), who, according to legend, would set up flaming torches alone the shore in order to ward ships away from wreckage on the rocks. As Lossiemouth continue to plug away in the Highland Football League, perhaps the prospect of future success can be their 'light through the night'.
I designed the home kit as a clear homage to another LFC, drawing inspiration from 1982 Liverpool home kit in particular. This colour scheme is reversed in the away kit.
ReBrand: Queen's Park FC
Posted on 10 June 2018 14 August 2019 Posted in graphicTagged badge, Blackburn Rovers, Blackburn Rovers FC, Blackburn Rovers Football Club, crest, emblem, Europe, FA Cup, football, Football Association Cup, Glasgow, insignia, Ladbrokes League 2, Lanarkshire, Latin, logo, QPFC, Queen's Park, Queen's Park FC, Queen's Park Football Club, rebrand, redesign, Scotland, Scottish Cup, Scottish League 2, Scottish League Two, Scottish Professional Football League, SPFL, SPFL League 2, SPFL League Two, Spiders, sport, The Spiders, UK, United Kingdom1 Comment
Queen's Park Football Club was established in 1867, making it the oldest football club in Scotland. It can be argued that no single club has had such an influence on the game of football in Britain—and in turn, the world—than Queen's Park. They invented the passing game (as opposed to the tactic of a 'rolling-maul' like that used in rugby, the primary tactic employed by all other football clubs of this early era), as well as the crossbar on goals, the half-time interval and free kicks.
Having been established in 1871, the [English] Football Association Cup competition predates the Scottish Cup by two years. In these early years, Queen's Park was invited to participate in the FA Cup and reached the final in 1883/84 and 1884/85, losing to Blackburn Rovers in both. Although other Scottish clubs were invited to participate in early editions of the FA Cup (including Cowlairs, Hearts, Partick Thistle, Rangers, Renton and Third Lanark ), Queen's Park are the only Scottish club to have ever played in the final.
In Scotland, Queen's Park won the first three Scottish Cup finals and had amassed ten Scottish Cup final victories between 1873 and 1893. The club's record would only be surpassed by Celtic in 1922/23 and Rangers in 1935/36. This means that, despite not having won the competition for 125 years, Queen's Park remain in the third position for all-time Scottish Cup victories.
Another distinguishing feature of this historic club is the fact that Queen's Park has always been an amateur side, reflected in the club's Latin motto, Ludere causa ludendi, 'To play for the sake of playing'. So committed has Queen's Park been to retaining their amateur ideals, that they resisted joining the Scottish Football League when it formed in 1890. Eventually, in 1900, Queen's Park applied for membership into the SFL and were admitted directly to the top tier. But that season saw Queen's Park beaten by Celtic in the Scottish Cup final, heralding the end of the amateurs' dominance of Scottish football.
The Queen's Park kit did not feature a regular badge until 1928, which has more-or-less remained the same ever since. This badge is heraldic in nature, featuring a black and white hooped shield (reminiscent of the iconic Queen's Park home shirt, from which their nickname, 'the Spiders', is derived) tilted anti-clockwise. The shield is topped by a helmet, from which emerges mantling, a torse and a crest of a lion rampant in red. The club motto is displayed on a scroll beneath the shield.
Given the club's illustrious history, I found the Spiders' badge one of the most difficult to redesign. Being that they are the oldest club in Scotland, I found it essential to include the year of their formation, as well as the club's initials and the Latin motto. I have included all of these features in a typeface of my own design, inspired by the script in several medieval illuminated manuscripts. As a centrepiece, I have included an illustration of a Victorian era football.
Both of the kit redesigns are based on historic Queen's Park kits. The home kit features the club's traditional tight black and white hoops (in use since 1873). In particular, this kit is inspired by the 1927/28 home kit and variations on said kit used until 1960. The away kit is inspired primarily by the home kit worn from 1872 to 1873, with dark blue and white hooped socks. This similar dark blue and grey colour scheme was also used in the home kit between 2016 and 2018 to commemorate the club's 150th anniversary.
ReBrand: Berwick Rangers FC
Posted on 23 May 2018 16 July 2019 Posted in graphicTagged Berwick, Berwick Rangers FC, Berwick Rangers Football Club, Berwick-upon-Tweed, Black & Gold, Black and Gold, Borderers, brand, branding, BRFC, Dream Team, England, Europe, football, Latin, logo, Lowland Football League, Northumberland, rebrand, redesign, Scottish Lowland Football League, SLFL, sport, The Black & Gold, The Black and Gold, The Borderers, The Dream Team, The Wee Gers, UK, United Kingdom, Wee GersLeave a comment
Berwick Rangers Football Club was formed in 1884 by a group of railway clerks from Newcastle, England who played a match against a team of millworkers from Dunbar, Scotland.
Until 2019, these 'Wee Gers' were the only club in the Scottish Professional Football League that isn't from Scotland (though, as of July 2019, the squad is made up entirely of Scottish players). Based in Berwick-upon-Tweed, Northumberland, England, just two-and-a-half miles (four kilometres) south of the Scottish border, Berwick Rangers played in the Scottish Football League and subsequent Scottish Professional Football League from 1905 until relegation to the Scottish Lowland Football League in 2019. Their departure from the SPFL came after a devastating 0-7 aggregate loss to Highland League champions Cove Rangers.
Due to the club's geographic significance, when first designing this badge in 2014, I found it difficult to pin down a single design that captured what their current badge offers – the heraldic symbol of the historic Scottish county of Berwickshire with a bear and a tree, the Scottish lion rampant and the English lion passant. Instead, I shared two simple designs. For the first design I set the bear upright against a football, within a minimalistic yellow shield including the club's initials above and the year of the club's founding below. The second design omitted any writing and simply featured a football upon which rested the flags of England and Scotland within shields. Below are these initial designs, which I published on 5 November 2014:
Ultimately, while I appreciated the minimalism of these initial redesigns, I found them lacking, especially as two separate ideas. In 2018, I attempted a second redesign, though I also found this unsatisfying. Now that the Wee Gers are rebuilding in the Lowland League, I've decided to give the badge another go. Included are the flags of England and Scotland in a mustard and black colour scheme. I've also included the Latin motto of Berwick-upon-Tweed, VICTORIA, GLORIA, MERCES ('victory, glory, reward').
The home kit features black and gold vertical stripes, used by the club in nearly every home kit since 1908. The away kit is dominated by the emerald green of the current away kit with gold features.
ReBrand: Livingston FC
Posted on 2 May 2018 6 August 2019 Posted in graphicTagged badge, brand, crest, Edinburgh, Europe, Ferranti, Ferranti Thistle, football, Ladbrokes Premiership, Latin, lion, Livingston, Livingston FC, Livingston Football Club, logo, Lothians, Meadowbank, Meadowbank Thistle, rebrand, redesign, Scotland, Scottish Premiership, Scottish Professional Football League, SPFL, SPFL Premiership, Spitfire, sport, Supermarine Spitfire, texture, Thistle, UK, United Kingdom, West LothianLeave a comment
The history of Livingston Football Club is one of the most tumultuous in all of Scottish football.
The club began its life in 1943, as the works team of Ferranti, who had set up a factory at Crewe Toll, Edinburgh for the manufacturing of gyro gunsights for Spitfire aircraft during the Second World War. The original club name was Ferranti Thistle FC. They played under that name until 1974, when the club gained admittance into the Scottish Football League.
Because their home ground, the former City Park, did not meet the SFL's requirements, and because of controversy arising from a team bearing the name of a commercial company, Ferranti Thistle moved to the Commonwealth Stadium (later called Meadowbank) and changed their name to Meadowbank Thistle FC. The team struggled in the lower divisions for many years and in 1995, they relocated to Livingston, changing their name to Livingston FC in the process.
After this move to West Lothian, Livingston FC began to show promise. By 2001, the club had gained promotion into the top tier and in this first campaign, the Livi finished third in the table, which meant that they qualified for the UEFA Cup (now the Europa League). Livingston would meet further success when they defeated Hibernian in the final of the 2003/04 Scottish League Cup on 14 March 2004. But Livingston's victory was bittersweet, as the club had entered administration on 3 February, eventually emerging in May 2005. That same month, Livingston avoided relegation narrowly. Ultimately, their stay in the top tier was ended when they finished the 2005/06 season at the bottom of the table.
In 2009, Livingston entered into administration for a second time and were in danger of outright liquidation. As a result of breaching rules on insolvency, the SFL took the decision to demote Livingston to the Third Division (the bottom tier). In the two subsequent seasons, Livingston won consecutive promotions, reaching the First Division in 2011.
In 2013, the SFL was replaced by the Scottish Professional Football League, and the First Division was renamed the Scottish Championship. At the end of the 2015/16 season, Livingston were relegated to League One (the third tier). But their stay in League One lasted only one season, with the club gaining promotion back to the Championship in 2017. In the 2017/18 season, Livingston secured second place in the Championship table. This gave them the opportunity to gain promotion to the top tier for the first time since 2006 via playoff, which they achieved in a 3-1 victory over Partick Thistle over two legs.
When redesigning Livingston's badge and kit, I kept this challenging history very much in my mind. Because of the abundance of thistles among Scottish football club badges, I opted to omit the thistle image from the new badge (and save it for clubs with 'thistle' in their names, like Partick Thistle and Inverness Caledonian Thistle).
Being that the club has been based in Livingston since 1995, I wanted to capitalise on that local identity. The acorns represent West Lothian (whose coat of arms features an 'oak tree fructed') and the three cinqfoils are taken from the Livingston family coat of arms. The crossed pickaxes represent Livingston's historical shale mining industry.
The Latin in the outer ring, Fortiter Omnia Vincit ('Bravely Conquers All') is the club motto, which was included in the club's badge from 1995 until 1999. I feel this motto is especially appropriate given Livingston's unlikely survival over the years. The lion rampant has featured in the Livingston badge since 1999 and I believe it is fitting for a Scottish club and accompanying the motto above.
For the home kit, I went with a black body and gold details, a colour scheme used numerous times since the club's 1995 move. The away strip is more adventurous, calling back to the Ferranti works team who manufactured gyro gunsights for Spitfire. The scheme is based on the Types A.1 and C.1 roundels used on Spitfires during the Second World War.
ReBrand: Kilmarnock FC
Posted on 24 April 2018 9 August 2019 Posted in graphicTagged Ayrshire, badge, Confidemus, crest, East Ayrshire, Europe, football, Killie, Kilmarnock, Kilmarnock FC, Kilmarnock Football Club, Ladbrokes Premiership, Latin, logo, rebrand, redesign, Scotland, Scottish Premiership, Scottish Professional Football League, SPFL, SPFL Premiership, sport, St Marnon, UK, United Kingdom3 Comments
Kilmarnock Football Club was formed in 1869, making it one of the oldest football clubs in the world. Before this time, Kilmarnock was an established cricket club, playing according to rugby football code in the cricket off-season. This rugby football code history is reflected in the naming of the club's ground, Rugby Park.
Technically speaking, Killie is the 15th oldest association football club in the world (the fifth oldest still playing league football and the oldest competing in top tier league football) and the second oldest Scottish club now playing according to association football code, after Queen's Park. As Queen's Park have always been an avowedly amateur club, Kilmarnock is the oldest active professional football club in Scotland.
Killie's honours include one top tier championship (1964/65)—which came after finishing as runners-up in four of the five preceding seasons—as well as three Scottish Cup victories (1919/20, 1928/29 and 1996/97) in eight appearances and one Scottish League Cup (2011/12) in six appearances.
The original Kilmarnock badge, featured on their strip from 1873 to 1887, consisted of a football topped with a hand of blessing. This hand symbol was borrowed from the Kilmarnock coat of arms, which itself is taken from the badge of Clan Boyd, whose seat is based in Kilmarnock. The hand represents the sixth-century disciple of St Columba, St Marnon (Gaelic: Cill Mhearnáig or Cill Mo-Ernóc), from whom the name Kilmarnock derives. From 1887 to 1977, the club's shirt did not feature a badge.
In 1977, an early version of the current badge was incorporated into the kit. This badge was altered in 1993 and is still used today. The current badge features a football and the hand of blessing, as well as additional heraldic symbols from the Kilmarnock/Boyd coat of arms, including the two supporting red squirrels and the blue and white heraldic wreath. The top of the badge features the Latin motto, Confidemus ('We trust'), derived from the Boyd motto, Confido ('I trust'). Below is my initial Kilmarnock redesign that was published on 10 August 2013: I was never quite satisfied with the redesign above. I have long appreciated the content of the current Kilmarnock badge, but have found the execution to be lacking. Ultimately, with my redesign here, I decided to go for something far more minimalistic, calling back to the original badge used from 1873 to 1887.
As far as the kits go, the home strip utilises the established Kilmarnock vertical stripes, first featured on the 1896 home strip and used throughout most of Killie's history. The away strip borrows its colour and buttoned collar from some of the club's earliest home shirts.
ReBrand: Hibernian FC
Posted on 24 April 2018 5 August 2019 Posted in graphicTagged brand, Cabbage, crest, Edinburgh, Europe, football, Hibees, Hibernian, Hibernian FC, Hibernian Football Club, Hibs, Ireland, Ladbrokes Premiership, Latin, Leith, logo, rebrand, redesign, Scotland, Scottish Premiership, Scottish Professional Football League, SPFL, SPFL Premiership, SPL, The Cabbage, The Hibees, UK, United Kingdom1 Comment
During the challenging years of the Great Famine in the nineteenth century, many Irish emigrated to Scotland, with most settling in and around Glasgow. Smaller groups of Irish immigrants settled in the east, especially in Dundee and Edinburgh. A particularly concentrated Irish population settled in the Cowgate area of Edinburgh and it was there that in 1875, Irish-born priest Canon Edward Joseph Hannon of St Patrick's Church was encouraged by Michael Whelahan to establish a football club in order to promote a life of temperance and religious adherence among the young Irish Catholic male population in Edinburgh. Hibernian Football Club was thus formed, with Whelahan acting as the club's first captain and Canon Hannon acting as the club's first manager.
By the late 1880s, Hibs were experiencing numerous difficulties due to mismanagement. When the Scottish Football League was established in 1890, the Hibees played no part in its formation. In 1891, the club's lease on their home ground expired and many key players left to join the ranks of Celtic, who were already making their mark on the professional game in Scotland. Hibernian seemed all but lost.
The following year, the club was reconstituted and a new home was acquired, this time at Easter Road in Leith. By 1893, Hibs had joined the SFL. Since that time, the club has proven itself as one of the most competitive sides in Scotland by achieving a number of significant domestic honours. The club has been crowned champions of the top tier on four occasions (tied for third most alongside Aberdeen and Hearts), most recently, at the end of the 1951/52 season. Hibernian have also won both the Scottish Cup and the Scottish League Cup on three occasions each (1886/87, 1901/02 and 2015/16, and 1972/73, 1991/92 and 2006/07, respectively).
The first Hibernian badge consisted of a harp within a shield, reflecting their Irish identity. From 1876 to 1879, their shirts featured the letters 'HFC' in blackletter across the chest. The Hibs' kits featured no badge from 1879 to 1980. It was during this period (1920) that Leith was incorporated into the City of Edinburgh. In 1981 the 'crown crest' was introduced, which consisted of a football topped by a crown and flanked by two olive branches. Some version of this badge was used until 1989, when a more modern badge was introduced. Hibs' current badge has been in use since 2000 and reflects much of their history. It features a ship to represent Leith, a harp to represent their Irish heritage and a castle to represent the City of Edinburgh.
While I consider the current Hibs badge to be very strong, I find it a bit busy and disunited. In my redesign, I opted to go for a full-on vintage look, with a typeface that calls back to the time of their foundation and the reintroduction of a harp as the primary icon. I also desired to include both the Leith and Edinburgh heritage by including both names. I used a 'V' instead of the 'U' in Edinburgh in order to reflect the city's current branding and the Latin in the club's name (Hibernia being the Roman name for the island of Ireland).
I find the dominance of the white in the redesign especially striking against the green field of the home strip (which is based on the classic Hibernian home strip of a green body and white sleeves). I've also incorporated a larger, offset harp in a lighter shade of green on the body of the home shirt. For the away strip, I decided to go with a yellow and dark blue colour scheme and a minimalised harp badge, the harp calling back to the first Hibs kit.

redpajama_set_name: RedPajamaCommonCrawl


text:
"I thought 'if I don't go, they will push all of us in the water' so I entered the pool"
Date and time: May 21, 2021 02:00
Location: At a place with three rivers between Basara and Kordunski Ljeskovac
Demographics: 3 person(s), age: 27, rest unknown , from: Afghanistan
Violence used: exposure to air condition and extreme temperature during car ride, insulting, water immersion, threatening with guns, destruction of personal belongings, theft of personal belongings, reckless driving
Police involved: Croatian Border Police and Intervention Police (IJP)
At 02:00 a.m. on May 21st, the 27-year-old respondent from Afghanistan departed from the border area in Šturlić, BiH together with his sister and her husband. They reached the Bosnian-Croatian border within a few hours.
In order to cross the border, they had to cross a river where the water was approximately 1.20m deep, so that the water was reaching their bellies. Afterward, they kept on walking inside Croatian territory. In the afternoon at around 2 pm, they were walking up a dusty mountain path, close to road number 1 near the village of Podmelnica, Croatia (45.101659, 15.571043). The respondent and the two other people of the group saw a police car parked some meters away and decided not to move and wait, hoping the car would drive away.
But they were detected by three police officers in blue shirts and dark trousers (most likely border police). The respondent remembers:
"When the policeman came, they took out their guns and loaded it like putting in a bullet and shouted 'sit down'"
When the group sat down on the ground, one of the police officers shouted at them "in a hard language" as the respondent stated, asking what they were doing there.
"We said that we have to stay out of our country and want asylum."
The respondent described how even though they expressed their intention to seek asylum multiple times, this right was denied by the officers, who according to the memory of the respondent answered:
"Here there is no money. You cannot come here. You have to go".
Then these officers brought the group to the main road. There, according to the respondent, two young officers from the intervention police, wearing sunglasses and dark blue shirts, and a white police van for prisoner transportation were waiting for them.
"They deported us in a big camion, like police use to catching the big mafias."
At the bottom of the van, there was a fixture for shackles. During the ride to the border, the group suffered extreme heat in the vehicle caused by the Air Conditioning, which was turned up really high. The respondent described how the heat and the reckless driving of the vehicle by the police officers led the group to feel as if they were lacking oxygen to breathe.
"We all went to the door to try to get some air, there was no air in the car."
When the van stopped at the place at the border, four more police officers with sunglasses and black shirts (likely of the same unit, IJP) were waiting. The respondent remembers the place of the pushback as a place with three parallel rivers (see map). One of the rivers has been formed in a way to create a sort of "pool" where the water reaches a depth of approximately 1.8m.
The police officers shouted at the three people to step out of the van. The respondent described how the group was forced to stand at the edge of the river bank and the police officers were making jokes about pushing them into the water. The respondent explained it as follows:
"First they tried to push all of us in the river, then my sister cried. Then they pushed me. I thought, 'if I don't go, they will push all of us in the water,' so I entered the pool."
Because of his inability to swim, the respondent had to grab a branch and managed to somehow cross the river by paddling with his hands. When the respondent got out of the water the police officers took their power banks and all three people's smartphones and broke the charging plug using an iron tool which could not be described in detail by the respondent. Finally, they smashed the displays on a stone, breaking them and then handing them over again to the group.
Indicating a direction, the officers reportedly shouted "there is Bosnia, go and don't come back!" After some meters, the respondent decided to take off his wet clothes and leave them in the woods. "They were soaked with water and too heavy to walk, I left them." At the main road, they reached Bosnia (R403b), just before the area of Šturlić, where the group was approached by an IOM car. The IOM workers gave them clothes and indicated the direction towards Velika Kladuša. The three people had to walk back for around 6 hours until they reached Velika Kladuša at night.


Hi Doc, I would like to try one of these, if the offer is still on at £225?
Yes I will PM you.
Thanks, payment and pm sent.
Doc...I assume the £225 offer, if still available is for a UK version only, not a North American version @120v?
Sorry not available at 120v.
I'm still putting my feelers around NVA and spotted this - firstly is your offer well and truly finished? Additionally can you just send the box and I screw in my own extension block? Also the evil smps that come with some hifi, does a bmu isolate each socket so that it doesn't affect other connected equipment?
All sockets are connected to the transformer none are isolated. We are not planning a batch build too many other things to do so no discount, that was an intro offer. I cannot sell them as a kit as we are playing with mains supply so we have to do the work to keep everything legal and CE. Once one is bought we cannot stop people doing things apart from that makes us disown them.
I've been reading elsewhere that the BMU transformer could hum slightly - is this still a possibility?


My wife is an artist. When she draws a portrait of person, she usually puts a photo of the person nearby and starts sketching features. How does she do this? She consciously alters her perception of the object: the face. She forgets she is looking at a face. She suppresses the concepts faces, eyes, and circles. Instead of interpreting what she sees as a thing she understands, she sees shade and potential pencil stokes. She describes this process as looking at something as if you had never seen it before.
In contrast, my drawing technique (if it can be called a technique), is to use some basic shapes like circles, squares, eye shapes, continuous line, or other mental templates for imitation. The underlying difference is that my wife's interpretation is data based and my interpretation is assumption based. I see a head and assume that an oval shape will be sufficient. I won't show you any drawings I made but they all look like a fairly talented 6 year old created them. I don't really see what's there.
The above shows that, at least in some contexts, consciously altering your perceptions by suppressing normal aspects of thought can positively affect your ability to analyze. Can we do this with search experience? I'm going to try.
What's it Like to Google?
I'm presented with a box. My cursor blinks and brings my attention to the left center of the page. Bright letters sit above this bar spelling out G-o-o-g-l-e. What a strange nonsense word. It sounds like a mantra. Was this word generated from an infants ramblings? The word has a two step feeling, "goo – gull". One two, left right, punch hook. Ninety percent of my screen is filled with whitespace. Two buttons, "Google Search", and "I'm Feeling Lucky" sit under my blinking cursor. I suppose I know what search does. What about feeling lucky? Is this a Dirty Harry reference? What does it do? I ignore it for now.
I type in gibberish: sai odsi oisvoij odaisj avds. No results. I try more searches, randomly finding things of interest. I try this over and over. I begin to type in more words until I find no search results.
***The above text describes a common task through the eyes of an individual who has never seen a search engine before.
To google is a two step process. One can estimate knowledge and discover the depth of content available by interacting with the little enlightening white bar.
This entry was posted in interaction and tagged experience, google, search, story by rhema. Bookmark the permalink.


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For more than 10 years Julia Rucklidge has been battling society's norms, highlighting the importance of nutrients on mental health.
Julia Rucklidge doesn't hold back. She has had her fair share of blows and setbacks, yet continues to battle through, because she knows that she is onto something worthy of the fight.
New Zealand is currently in the middle of a mental health crisis, and I don't use the word 'crisis' lightly. If you think this is something that doesn't affect you, think again.
In a media release by the Mental Health Foundation (MHF), chief executive Shaun Robinson said, "Half the New Zealand population is living with mental health and wellbeing issues right now".
Half the population.
This affects you. If not directly then through your family, your friends, your community or your business.
Something needs to change; the Mental Health Commissioner's Monitoring and Advocacy Report 2018 noted that mental health and addiction services are under immense pressure and many needs are not being met.
"When you go into any field you go in with great optimism," Julia says, "you believe the treatments that are available currently are working and that people are getting better. In the area of mental illness, I can't confidently say that is the case." We know nutrients are vital for brain health; 10 years ago that would have been an absurd suggestion and that is what Julia has been fighting, and she is winning – slowly.
Julia has a PhD in clinical psychology and is a professor at the University of Canterbury. She has encountered many a sleepless night and jumped through many a hoop to get the results she has seen with nutrients — but there is still a hard slog ahead.
How the connection was made
While Julia was amid her PhD at the University of Calgary, Bonnie Kaplan, Julia's PhD supervisor, was approached by a group of families in Southern Alberta, Canada, who were treating themselves with nutrients. "Some of them had very serious psychiatric disorders and they were claiming they were getting well," Julia reveals.
These families were not scientists but they knew if they were going to make controversial claims they had to be able to back them up.
"My supervisor was fairly sceptical but then they sent her data, she agreed to do a clinical trial back in the late 90s."
This was enough to catch Julia's attention, but although she was intrigued, she didn't think that moving from experimental research to the effects of nutrition was her place. "I thought psychiatrists should be doing it, but none of them thought it was worthy of investigation."
In the interim, after working in Toronto at The Hospital for Sick Children (aka SickKids) for two years, Julia and her husband moved to Christchurch after Julia nabbed the role of child psychologist at the University of Canterbury in 2000. By around 2005 Julia had become increasingly dissatisfied with, and aware of, the outcomes for people with mental illness.
Bonnie was publishing preliminary trials on nutrition, families were saying they were getting better and Julia caught wind of suggestions that micronutrients may be the way forward.
"As scientists we should be investigating other options no matter how crazy those ideas might be, no matter how controversial or how much they contravene our current way of thinking," Julia says.
And with that in mind she thought "why don't I just study it, it can't be that difficult".
Naivety, as it seems, was bliss.
"Little did I know that this was going to be an unbelievably interesting journey, but one filled with controversy and obstacles. I didn't expect the level of criticism I received from professionals in the field who held the common belief that nutrition is irrelevant to mental health. I can assure you now, it is not."
The hoops
Julia's approach is not like most, not just in her research but how she goes about it.
"I want to determine if it works and that upsets some researchers, because they believe you have to have a hypothesis and know why it might work before you start determining if it works or not, and I think well… you could do it that way," she muses.
"It started with these families that claimed they were getting better; let's first determine if they were right."
This approach has meant nothing has come easily to her.
Julia's first trial looking at mood stability in adolescence didn't even make it past 'go'.
After originally being turned down by the Canterbury Ethics Committee, Julia had to go to the National Board in Wellington to appeal the decision.
"A lot of scientists would have given up. I was constantly asking myself 'Am I doing the right thing,' 'Am I being blinded by something that everyone else is seeing, that this is such a dumb idea'?"
Regardless, persistence was key and it was agreed the study could go ahead, but the beginning was also the end.
"We couldn't recruit anyone into the study because no one would send us patients."
Potential referrers thought there was absolutely no way micronutrients would be effective.
As such, Julia had to essentially abandon that study, but not willing to give up she moved on to the effects of nutrients on people with ADHD.
Julia was turned down for every grant she applied for, but the study on ADHD finally got underway. She did all the leg-work, collecting all the data, meeting with patients and doing so on no more than a few thousand dollars, all while in the face of scrutiny and scepticism.
She was asked, "Julia you're handing out these nutrients, how do you know that they are not harmful?" Julia accepts that as a valid question, but when compared to other medications already on the market such as Ritalin LA, commonly used for ADHD, with side effects such as suicidal thoughts, new or worsening aggressive behaviour, seizures, blurred vision, restlessness — the list goes on – Julia says micronutrients have yet to present any unfavourable outcomes.
"In the short term, based on our data over 10 years, I feel confident that we won't cause any detrimental effects with micronutrients. We take blood samples to ensure there are no adverse effects on people's kidney functions and liver functions etcetera.
"We have never had a serious adverse event in our clinical trials and that will more typically happen when trialling medication."
We consume nutrients every day in our diets and the micronutrient formula is ultimately a mixture of essential vitamins and nutrients needed for our brains to function optimally.
Regardless of the naysayers and the uncertainties, Julia stuck to her guns — and then the earthquakes struck.
"I just remember thinking 'this is so unfair', there had been so many battles and obstacles to get this research underway… it was just one thing after another, you can't help but take it a little personally," she laughs.
But her persistence paid off and perhaps Mother Nature was lending her a helping hand. "Not only did we finish our first randomised clinical trial, we started the earthquake trial and that by far is the trial I am most proud of."
"You never forget patient zero"
Though breaking through mindsets hasn't come easy, Julia has seen her fair share of golden moments, and it all began with patient zero.
"Patient zero is the first time where you're absolutely terrified you're going to kill someone with vitamins and minerals, but you have this faith," Julia explains.
"It was a family with an adolescent with Obsessive Compulsive Disorder (OCD) who I had worked with using cognitive behavior therapy. Over the years I had worked with him, he had shown minimal progress, so we trialed micronutrients and within two weeks his symptoms were gone — you don't forget that.
"Especially when you have invested everything in traditional approaches to no avail and then to have such a substantial change in such a short amount of time, it got my attention."
And the success hasn't stopped there. In Julia's first open-label trial for people with ADHD, again yes she was nervous that she would cause harm, but person after person was coming in saying they felt so calm and focused, she knew then that she was on to something.
After the September earthquake, Julia was feeling pretty hard done by but it presented an opportunistic pilot study. Those who happened to be taking micronutrients at the time of the earthquake, recovered faster in terms of stress and anxiety, compared to those who were not taking micronutrients.
When the February earthquake struck Julia was about ready to give up. Her home was damaged, the psychology department was shut down and she was working off minimal resources in Canterbury University accommodation, intended for important guests. But after seeing so many people becoming well and the effects on those after the September earthquake, she had a will to continue fighting.
Not only did she complete a randomised control trial with stressed and anxious adults, her lab also investigated anxiety and stress in children following the Christchurch earthquakes with remarkable results.
"I shouldn't have been surprised because I saw it after the September quake, but when you realise the extent of benefit that we provided to Cantabrians… at the end of the day it was a pretty cheap way to address the mental health needs of a population after a disaster."
The push continues
"I can get excited by the results but I can also get unbelievably frustrated about how difficult it is to translate research into practice."
Julia is a common face in media, she has presented at TEDXChristchurch which has seen more than 816,000 views on Youtube and she recently grabbed Jacinda Ardern's attention when she saw the opportunity, and yet her voice continues to be somewhat unheard.
"It saddens me that we have a crisis on our hands with children in schools who are suffering from anxiety, when we have done research with children after the quakes showing robust improvements in their anxiety with the use of nutrients."
Clearly there is still a steep mountain to climb, but Julia has a strength and determination like no other.
"It's important for us to be investigating new approaches. There are so many people who have been completely let down by the mental health system and for the most part, their voices are ignored. What the Government continuously wants to do is more of the same.
More of the same only gets us more of the same." Mental Health Commissioner Kevin Allan even said it himself in his key findings from his recent report, "More of the same will not deliver the well-being and recovery-oriented system that is required".
That is why Julia is on this crusade; she knows, no matter the lack of support she receives, that what she is doing is helping hundreds of people.
If we can conquer mental health and well-being issues we could see thriving communities, families and businesses and micronutrients could be an integral part of the solution.
By Natalia Rietveld
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Kemenangan Tani is een bestuurslaag in het regentschap Medan van de provincie Noord-Sumatra, Indonesië. Kemenangan Tani telt 5255 inwoners (volkstelling 2010).

Plaats in Noord-Sumatra

redpajama_set_name: RedPajamaWikipedia


I've been a 49ers fan since I was a kid. My childhood hero Steve Young even came to a production of "8" in NYC. Come on Culliver, man up, don't make me wear PURPLE with my GOLD on Sunday. Pathetic. It looks like Baltimore Ravens linebacker Brendon Ayanbadejo isn't the only player who has voiced his thoughts on gay rights during Super Bowl week. According to Martin Rogers of Yahoo! Sports, San Francisco 49ers cornerback Chris Culliver appeared on Artie Lange's radio show and made disparaging comments about homosexuality.


Enslavement to the machines we have created is, in a nutshell, the theme of these two formidable books. Both are utterly convincing assaults on the ideals, ideologies, delusions and even the engineering of the Silicon Valley elites that aspire to remake the entire world and its inhabitants as machine-readable code. Yet they are two quite different books.


Trick or Treat! Scare up some delicious Halloween recipes from kid-friendly snacks to Fall desserts. We promise none of these recipes are too spooky or scary! PBS Parents has some great Halloween safety tips and PBS character costume ideas, and don't forget to send us photos of your carved pumpkin!
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This instrument of 23 stops (30 ranks of pipes) across two manual and pedal is the fourteenth new organ built by the Buzard Pipe Organ Builders of Champaign, Illinois. The new instrument replaces a Wangerin Organ, built in Milwaukee in 1922, which was reworked and added to in the 1960's and 1970's.
If a new pipe organ was going to be built at Immanuel Lutheran church, it had to satisfy several criteria, not the least of which was that it would have to have an incredibly long life. The Organ Committee wisely didn't want the Congregation to ever be faced with having to releather the entire organ's windchest actions after 20 years. These "musts" were considered cornerstones of a new organ's design.
The ability to easily move the console.
Substantive discussions with members of the Organ Committee and the Consultant identified the musical needs of the Church, both present and future and, reconciling them to the Church's acoustical environment, we arrived at the tonal specification, pipe scaling and placement of the organ in the room. Upon hearing our English inspired instrument at the Episcopal Chapel of St. John the divine in Champaign, the Organ Committee enthusiastically wanted the Immanuel Lutheran organ to should just as warm and round in tone, but with the ability to be just a bit brighter for more appropriate rendering of baroque music.
Some members of the Committee were particularly fond of our Flute Celeste, a curious, delicate stop originally pioneered by the late Walter Holtkamp, Sr., in which two pipes are made in one pipe body. It is installed in this organ on the Great. Others thrilled to the smooth pervading power of the Major Tuba, solo stop voiced on high wind pressure, which we mounted horizontally atop the main case. Everyone wanted this organ's full Principal chorus to be grand scale and exhibit a smooth, silvery tone quality, which it is and does.
Probably the most interesting visual and tonal feature of this organ is the location of the Great Division which is projected over the front edge of the balcony rail. Since the church's acoustics are not as generous or lively as we would have liked, it was important to get the sounds which are used with the congregation as close to them as possible. The Swell and Pedal Divisions are housed in a taller case in the balcony.
The cases feature shapes and forms found elsewhere in the Church, and are made of solid white oak. The main case in the balcony has a three-sided central projection surmounted by a canopy and gold-leafed crown, in imitation of the reredos. We like to incorporate color into our cases in tasteful degrees, so the pipe-shades are of contrasting wood color and highlighted with gold leaf and red enamel, relating to other colors in the room. The front pipes are made of lightly polished English tin presenting an elegant, soft quality to the facade.
The consultant was the Rev. D.J. Dunlap.


We're just encouraging ourselves in this study to say, "Okay, let me step back for just a moment and really be truthful with myself and where I am. Am I justifying many of these methods that I'm using?" And you're saying, "Pastor, we all have to work. We're to work and live by the sweat of our brow." We're not saying don't go to work. We're not saying to isolate yourselves from the world. We're saying don't become proficient in the world. We're saying don't seek the treasures of the world, its wisdom, its methodology. We're talking about cutting back, becoming more simple, getting more quiet time, hearing what the Spirit of God is saying to the church in this hour. And what He's saying is this, "Come out, come out, come out from among them. Don't touch the unclean thing, and I will receive you" (2 Corinthians 6:17). Are we saying, "Oh, it doesn't hurt to camp here. It doesn't hurt to pitch the tent toward Sodom. I'm not actively involved. I'm just gazing upon them. I'm just admiring their wealth. I'm just admiring their proficiency, their dedication, their skills. It's amoral. There is nothing wrong with it."? Seek things above! If you're going to gaze on something, gaze at the things that are above. The world's wisdom is dangerous. It gives us power. It gives us independence. It brings us security. It's what killed Solomon. It's what almost killed Lot. It was the main thing that God had to drive out of Job. Job, in all of his wisdom and his understanding and his ability to argue against God's methods, and finally, he came to the place of putting his hand over his mouth, didn't he?
Father hasn't told me to do this, or I believe, I hope, that I would. I hope that I would! But if Father was to speak to me today and say, "I want you to walk away from everything. I want you to sell everything you have. I want you to walk away from it. I want you to absolutely start, today, living by faith alone, with nothing. Sell it all, give it to the poor, and come and follow me." I wonder how many "wise" reasons I could come up with not to do that. Could you all come up with some? Would you all help me if I needed that? If I ever have to argue against God, could you help me come up with some arguments? Which ones have you used? What works best in your life?
There's a wisdom that's from above. "Who is a wise man and endued with knowledge among you? let him shew out of a good [lifestyle] his works with meekness of wisdom" (James 3:13). Let him live a holy life with a meek and quiet spirit. "Come and learn of Me, for I am meek and lowly" (Matthew 11:29). Whose works are with meekness of wisdom. A wisdom that doesn't have self-confidence accompanying it, a wisdom of humility, a wisdom that doesn't answer to reason. The wisdom of God that is pure and peaceable and gentle and easily intreated and full of mercy and good fruits, without partiality, and without hypocrisy (James 3:17). This wisdom that is, in all ways, pointing to the glory of God. God is the source. God is the recipient.
So, there are two wisdoms, the one that's from above, and the one that is from below that always generates strife and confusion and every evil work (James 3:16). You see, the moment that you bring worldly wisdom into the community, it's starting to bring strife. It's offensive to children of light; it's offensive to the truth. Every schism we've had here, every family that has left here, is because they were offended by light and truth, because they couldn't get us to bow to that one little twist of worldly wisdom that they wanted to apply to these circumstances. Do you think it might only take one, just one thing, to cause us to turn our backs and walk into the world's wisdom? How much of the world's wisdom do you think we have to embrace to remove us from the wisdom of God and the kingdom of God? What do you think the percentage would be? It's not a percentage. It's one! One decision against the Word of God, one elevation of the world's wisdom and methods and making it equal with God, is having another god before Him. And so, here we are. As we're looking at this subject, and we're seeing, then, the vitalness of apprehending the wisdom of God, and knowing what's opposing it. We do not want to be ignorant. What's opposing God's wisdom is another parallel kingdom, another wisdom.


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Culture & Heritage The gutting of Beirut's Roman racetrack
We often worry about extremists groups like ISIS destroying history in the Middle East. But in Beirut, private capital and well-connected developers are also wiping away relics of our ancient past. The following column was first published in Bold Magazine.
Partially excavated Roman hippodrome walls in Beirut. The site has now been cleared for private development
By Habib Battah
With its grand chariot races and some 200,000 spectators, the Circus Maximus was the greatest stadium in the Roman empire and remains one of the largest in human history. Today however, it is little more than a sunken green field in the heart of contemporary Rome. Spanning over half a kilometer in length, this plot of land may have seemed lucrative to real estate developers, but the Circus grounds have been preserved as a public park. Compare this to Beirut, where a major Roman chariot race track was recently uncovered but its grounds are now being destroyed to make way for six luxury villas.
In fact, when it was unearthed only a few years ago, Beirut's Roman racecourse or hippodrome contained far more ruins than can be seen in Rome's Circus Maximus today. But few Lebanese would have a chance to look at them.
Working secretly behind large construction walls, archaeologists discovered what was believed to be a section of the 2,000 year old stadium seats, the paved central median where an obelisk was placed, dozens of columns, corinthians and carved features as well as a 100 meter stretch of the foundation wall, forming a loop that traces the path of the ancient race circuit. But all this meant little to the villa developer, who incidentally was a minister in cabinet when he began construction.
The minister, Marwan Kheireddine, claimed the land was worth $60 million and thus could not be sacrificed. When asked if preserving the site might also have a value, he shrugged. "Ninety percent of the hippodrome is gone," he told me during an interview for the BBC a little over a year ago. His colleague, then Culture Minister Gaby Layoun had green-lighted the project, defying three previous culture ministers who had called for the site to be protected.
The Lebanese public, which is largely kept in the dark about archeological discoveries, only got wind of the story through news leaks. A protest was organized and complaint lodged at the Beirut governor's office, but it was too little too late and construction resumed a few weeks later. Today, a giant crater pierces through the heart of the remaining hippodrome track. Because the site is near the home of former prime minister Saad Hariri, access and photography of the area is strictly prohibited. The destruction can only be seen from Google Earth.
A gaping hole has been punctured in the hippodrome grounds to make way for development. Compare with below image from 2013.
The hippodrome grounds in 2013 before it was destroyed for real estate excavation.
The Beirut race track is believed to have been one of the greatest of five hippodromes in the Levant, a testimony to the importance given to ancient Berytus in the Roman Empire. First century texts reveal that 1,400 gladiators fought there in a single day.
Looking out across the barren Circus Maximus grounds during a recent visit to Rome, I remembered the minister's words: "What we found is not worth preserving," he had told me. But who makes that decision and on what criteria is it based?
Why is barren chariot track protected in modern Rome, a city full of well-preserved ruins, while a track with extensive remains is not worthy of preservation in Beirut, where so little is known about the city's prominent Roman past? Unsurprisingly, neither the developer nor the culture minister have any background in ancient history or archeology. They claim to have relied on experts, but their deliberations were never made public.
It's not only world history that is at stake. Contemporary Rome is a verdant city full of towering pine trees and gorgeous parks yet planners still felt it was prudent to keep the Circus Maximus as an additional open space. It is also used to host community events and concerts. Last year The Rolling Stones performed on the Circus grounds, drawing over 70,000 fans.
The Circus Maximus in Rome is largely a green field, yet it was still preserved as a historic and public space.
Contemporary Beirut, by contrast, is an urban jungle with a pittance of green or public space. Its pines–once similar to those in Rome– have largely been decimated by development and there are no large parks open to the public. With its grassy hillside and scattered columns, the Beirut hippodrome provided an opportunity not only to preserve national heritage and inspire future generations but also to add some breathing room to a labyrinth of concrete sprawl. One can imagine the space attracting tourists and locals alike– a history class field trip or just a place to enjoy lunch in the city while imagining its storied past. "It could have been a destination," veteran Dutch archaeologist Hans Curvers, who led the Beirut hippodrome excavation, told me. But now in the hippodrome's place, there will be more walls and security guards, yet another gated community accessible only to a few millionaires.
Minister Kheireddine, who owns a bank and several other real estate projects, touts the fact that he has offered to host a fraction of the hippodrome wall in his compound's car garage. The public will supposedly be able to glimpse a portion of its stone surface through a ground window. But the neighborhood is so tightly policed to protect its well-heeled residents that pedestrians are not even allowed anywhere near the street that leads to his project.
The hippodrome is not the only ancient site lost to speculative luxury real estate. Activists and archaeologists say dozens of ruins have been discovered and razed during the post-war reconstruction of central Beirut. Many of those sites have been replaced by the type of glass and steel towers one can find in any city. Drive past them at night you'll find barely a light on. Obviously few Lebanese can afford their astronomical price tags, and those who can are often wealthy foreign nationals seeking a rarely used vacation home. Why are such projects given more weight than sites that could benefit the local population, who actually live in Lebanon?
The silver lining is that outside the capital, away from the unregulated construction boom, many priceless sites have survived. Among them is the temple of Bacchus in Baalbeck, which is in far better shape than most of what one encounters in Rome. In fact, a temple that looks like Bacchus can only be seen as a 3D rendering in videos shown at Italian museums that give visitors an idea of what ancient Rome once looked like. Detailed descriptions, artist sketches and audio guides can also be found at nearly all sites, bringing the ruins to life and helping visitors further appreciate where they are standing and what they are looking at. But at ancient sites across Lebanon, one can rarely find a text sign, let alone an interactive exhibit. Should we be surprised then, that locals often ignore these wonders, which frequently fall into disrepair, abandoned or laden with piles of garbage?
Still from a video presentation at a Roman museum. Multi-media visuals help visitors appreciate ancient sites, where little remains today, such as present day Palantine Hill below.
Ruins at Palatine Hill are less preserved than many temples in Lebanon, yet Lebanese authorities barely provide signs to present them to the public.
Over recent years and through the help of social media, activist groups have offered a ray of hope, standing up to well-connected developers by secretly documenting discoveries at construction sites, enduring harassment or physical assault. Those in power should make their lives easier. We know that our political leaders–many of them millionaires– enjoy the attractions of foreign cities, a few even have villas in Italy. Would it be too much to ask them to help celebrate some of those same features at home? Would it be too much to ask our leaders to prioritize national treasures that can be enjoyed for generations over get-rich-quick schemes that will mainly benefit their family and friends?
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1,000 channels and nothing is on
Lebanese Forces seize traffic lights


JUST LIKE ME TOYS IS THE HOME FOR BLACK AND ETHNIC DOLLS.
We specialise in good quality dolls and clothing.
Our dolls are carefully chosen for their quality, beauty and inspirational attraction. They are excellently crafted and beautifully presented.
Just Like Me Toys is home for Black and Ethnic Dolls. At Just Like Me Toys you will find an extensive collection of children's dolls and dolls clothes for you and your child to love. We have the beautiful Llorens crying and talking soft-bodied doll range with an exquisite clothes range. We have the beautifully designed Poala Reina Everyday girl doll sporting her Afro hair that can be styled using ribbons and other hair accessories. If you are looking for a baby doll, rag doll, anatomically correct doll , look no further. You can also choose from our colourful range of African print designs. We hope you have fun browsing through our doll collection which will be updated as and when we have new designs. We are an independent toy shop. If you have any comments or suggestions for the site, or have any questions at all, we would love to hear from you.
Kaya Rag Doll is a lovely soft cuddly doll by Just Like Me Toys. Her body is made with brown polyester fabric and polyester fillings. She has black eyes made from plastic and a tiny stitched-on month. Her hair is woollen, rasta style, long and black, and is secured with two yellow ribbons into ponytails. that matches her shoes. She stitched on yellow shoes.
Kaya's clothes are colourful. The dress is an all-in-one pinafore made from African print and is worn with white blouse. Beneath her dress, Kaya wears a white pair of bloomers.
Kaya's clothes and body are machine washable. She is suitable for children 3 years onwards due to objects that can be removed.
Kieana doll is a crying talking doll with a dummy that helps to calm her down when she cries. Her head and limbs are smooth to touch and is slightly scented. Her body is made from fabric. Her voice box is secured inside her back, which once activated, she cries and calls "Mama, Papa" until she gets her dummy.
Kieana is wearing a beautiful printed dress with matching shorts and green jacket with cuffs that matches her dress. She has matching green booties and wears her hair in two ponytails at the top of her head adorned with green hair ties.


OMOD POE XLR is a module for your RED DSMC2 camera that combines professional in-camera audio with wireless lens control.
Lens control via RTmotion's MK3.1 hand controller and RTmotion Thumbwheels. Connect a single RTmotion lens motor for one axis PL lens control. POE XLR allows control of focus and iris of EF lenses over RF at ranges up to 1500 feet, making ideal for drones. You can also control the single axis PL lens motor over wifi with Foolcontrol.
LEDs for level metering and peak warning indicators.


text:
Q: How to write a python function that receives a list of function name-strings to evaluate, and stacks each function's output into one DataFrame I have 3 Python functions (full-on def functions) that each output a 2d numpy array (row vector) of the same size as one another. These functions are alternative approaches/answers to some same core problem.
def fun1():
    return row_array

An identifier name (a string) corresponds to each of these functions, so that a full list of these function names would be
names = ['fun1','fun2','fun3']

How can I attach these names to the corresponding functions quickly as a pandas.DataFrame?
all = pd.DataFrame([['fun1', fun1], ['fun2', fun2]])

Finally, I would like to write a master function that lets the user send  to it a list of names of desired functions to call, which could be all or a subset of them, and this master function evaluates each called function only, and stacks their respective row_arrays on top of each other into a squarish pandas DataFrame. In other words, aggregate all desired "alternative answers" into one data structure for viewing, so that at any later time I can repeat with a different subset of names.
What's the most efficient way to do all of the above without a series of if name is in list conditions?

redpajama_set_name: RedPajamaStackExchange


OVERVIEW: Webshoz' smart digital containers syndicate content and track engagement, a sorely needed tool in the hot "content marketing" industry used by companies to generate backlinks and to engage users with information relevant to them (non-advertising). In the last 2 years, social sharing has become the rage as well as companies using content creation as a mechanism to entice and engage users (because consumers hate ads). Content creation can't scale without software tools, which Webshoz has. We are the only company in the content marketing space that has developed a sophisticated proprietary solution for moving large infographics across multiple sites with a shareable container, which tracks every movement of it (clicks & shares). Our software is done and being modified as we speak to accommodate the uniqueness of the infographic's requirements - it's large, and it's a jpg. This will be completed by September, 2012.


LANSING, Mich., March 26, 2019 — Neogen Corporation (NASDAQ: NEOG) announced today that its revenues for the third quarter of its 2019 fiscal year, which ended Feb. 28, were $97,700,000, up 3%, from the previous year's third quarter revenues of $94,903,000. Current year-to-date revenues were $304,424,000, up 5% compared to $289,811,000 for the same period a year ago.
Third quarter net income was $13,073,000, compared to the prior year's $16,586,000. Earnings per share in the current quarter were $0.25, compared to $0.32 a year ago. Last year's third quarter included favorable tax adjustments totaling $2.9 million resulting from corporate tax reform enacted in December 2017. Current year-to-date net income was $44,361,000, or $0.85 per share, compared to $45,600,000, or $0.88 per share, for the same period a year ago.
The third quarter was the 108th of the past 113 quarters that Neogen reported revenue increases as compared with the previous year — including all consecutive quarters in the past 13 years.
Neogen's gross margin was 45.7% of sales in the third quarter of the current year, compared to 47.0% in the same quarter of the prior fiscal year. The gross margin percentage decrease was primarily the result of mix shifts within both the Food Safety and Animal Safety segments towards products that have gross margins lower than the segment's historical average, and adverse effects from the strengthening U.S. dollar. Expressed as a percentage of sales, operating income was 15.0% for the current quarter, compared to 16.8% in the third quarter of the 2018 fiscal year.
Revenues for the company's Food Safety segment increased 8% during the third quarter compared to the prior year quarter. Sales of Neogen's rapid diagnostics to detect natural toxins increased 17% in the current quarter, including a 35% increase in sales to detect the mycotoxin deoxynivalenol (DON) in grain. The improvement in sales of DON test kits was boosted by the increasing adoption of Neogen's new Raptor® testing platform, which automatically analyzes up to three samples independently and simultaneously. A 26% increase in sales of the company's rapid tests for histamine also contributed to the increase in sales of natural toxin tests for the quarter. Histamine is a spoilage toxin produced when certain species of fish, especially tuna, are improperly stored following harvest.
Compared to the prior year quarter, sales of Neogen's foodborne pathogen detection tests increased 16% — including a 45% increase in sales of tests to detect Listeria. This growth was largely the result of a nearly five-fold increase in sales of the company's innovative Listeria Right Now™ test system, which detects Listeria in environmental samples in under 60 minutes — without the need to enrich samples.
Sales of the company's general sanitation products, including its AccuPoint® Advanced product line, increased 11% in the third quarter of the 2019 fiscal year, compared to prior year. Sales of its rapid diagnostics to detect food allergens, including gluten, milk, soy and peanuts, increased 7% in the current quarter.
Despite the adverse currency translations in the current quarter, Neogen's European operations revenues rose 11%, aided by growth in genomics services and stronger sales of DON test kits. Revenues from the company's food safety operations in Brazil rose 40%, and its Mexico-based operations grew 19%. Neogen India's sales increased 94%, albeit from a small base, and Neogen China's revenues increased 9%, each on increases across their product offerings. Revenues from Neogen Australasia, which Neogen acquired in September 2017, more than doubled in the current quarter compared to the prior year.
Neogen's Animal Safety segment reported a 2% revenue decrease for the third quarter, largely the result of lower sales of products to distributor partners into the animal protein market, including rodent and insect control products. End markets have been affected by difficult economic conditions in the production animal markets, exacerbated by tariff disputes between the U.S. and China. However, sales of the company's detectable needles rose 17% while cleaners and disinfectants increased 18% and vaccines rose 13%.
Neogen's worldwide animal genomics business recorded an increase of 15% in the third quarter of fiscal 2019 compared to the prior year. This broad-based increase was aided in part by strong revenue increases from its genomics laboratories in Scotland, Australia, and Brazil, and included revenue increases from genomic testing of beef and dairy cattle, swine, poultry, and companion animals around the world.


"...after the drone came out from the clouds the view was spectacular and got me completely astonished and, without breathing, I had the time to take some shots before the sun went down and the cloud got higher hiding everything."
Of the winnining entries from this year's Dronestagram photo contest, one image stood out in particular.
The first place winner for the travel category was taken by Italian photographer Francesco Cattuto in Assisi, Italy. While on a sunset walk with his girlfriend on a foggy day last year, Francesco decided to launch his drone. As it climbed above the weather, The Basilica of St. Francis of Assisi became visible poking through the fog. In the resulting image, the Basilica appears to be floating through the sky.
Francesco took the photo using his DJI Phantom 3 Professional Quadcopter. He says he would like to use his quadcopter to photograph over Rome, Florence, or Venice, but local drone regulations do not yet permit him to do so. Francesco has taken his drone to the Maldives and hopes to travel to Australia, Africa, and South America.
2nd Place—Travel "This image was captured while honeymooning at Cable Beach, Western Australia. We rented a 4WD and drove 8,000 klms around outback Australia. I like the 100% vertical downward point of view that is so well captured by camera equipped quadcopters."
3rd Place—Travel "I was on a road trip in Gran Canaria Island in Spain where I captured some aerial shots of one of the most amazing beaches in the world - Playa de Amadores."
1st Place—Nature "I had been spending hours on Google maps, in satellite mode, trying to locate interesting patterns and places. I all ready had a pretty good idea about what I should expect when I arrived at the location. To my luck it had snowed all day so that the pine wood really stood out."
2nd Place—Nature "We wanted to present the traditional Romania in its full beauty. We were travelling by car and suddenly along the road from the distance I've spotted the sheep herd. 99% of the time I'm travelling with my drone."
3rd Place—Nature "This picture was very difficult to catch because off ascending hot-air and 50Km/h wind. There was also sulfur next to the volcano so I need to have a mask while piloting."
1st Place—Sports "We hiked for miles looking for the perfect line, and then spotting this amazing crack that was about 400 feet off the ground. Using the drone, I was able to capture images that would have never been possible before!"
2nd Place—Sports "I work as a photojournalist in the local newspaper, La Opinión, and I was assigned the task of taking a picture of the swimming competitions , which were held in the city , but instead of taking the same photo as always, it occurred to me to fly my drone to try to achieve something different, the result, an overhead photo of athletes warming up to begin the competitions."
3rd Place—Sports "picture was taken in the Chugach Mountain Range outside of Cordova Alaska. Its subject is my friend and guide Jason Bilek Opening up some turns on a giant mountain face we called Buzzy's. Its about 45-50 degrees and a very fun run. My fingers always get cold while I fly up there but the results are ALWAYS worth it."


text:
24 September 2000 : Volume 2 Issue 34
Adur Quality of Life: Our Shared Vision
The Adur Strategy for Sustained Development
This document is being prepared to go before the Committee for circulation in draft form for contributors comments to be received
circa 10 October 2000.
Contact: Natalie Brahma-Pearl, Adur DC. Tel: 01273 263347
Brighton & Hove Local Plan 2000
The First Deposit Draft has been published.
This is a large document with colour maps.
Future of Shoreham Port
David Vaughan (I am sure of his first name) spoke about Port of Shoreham at the Southwick Royal Legion on 19 September 2000.
The following items arose, which have not been all confirmed before:
1) The plan involves consolidation of the Port (removing the wharfage space by over 50%) which in common English means making the Port smaller with less business, jobs, and less port traffic, (although if homes and small businesses are built the actual total volume of road traffic will increase). Timber vessels can be unloaded much quicker nowadays to a faster turnaround.
2) The plan involves the reclamation of Southwick beach for warehousing space, effectively, and probably actually totally removing this amenity from public use.
3) The harbour has lost trade to other ports who are able to provide better facilities, e.g. Cocoa, and to road hauliers e.g. Wine (now shipped bottled.)
4) The existing inadequate roads not effect the running of the port, and they will only be improved e.g. a tunnel, to lessen the impact on local residents.
5) There will be another Moss pretty pictures presentation next summer.
Comments and further information are on the
(you have to join the group, and think of a password)
Latest:Halcrow Group Ltd are in the process of undertaking the Environmental Assessment of the contaminated land on the south side of Shoreham Harbour canal and they will be presenting an Exhibition in October 2000.
The lizard originally identified as the European Wall Lizard, Podarcis muralis, which poked its head out of flint wall in which a sprig of Bittersweet was growing, on the Old Fort, Shoreham Beach is almost certainly an adult Common (or Viviparous) Lizard, Zootoca vivipara.
22 & 24 September 2000
In light rain on both days I came so close to low flying Sparrowhawks whilst cycling, I thought we going to collide, but this bird of prey's superior eyesight enabled to soar quickly out of the way. The blunt forehead of this bird was particularly noticeable and it looks a much bigger bird close-up.
The rain has finally arrived, with squalls throughout the afternoon, and thunder with torrential rain in the evening. Chris Alcott spotted a waterspout/ tornado off the Shoreham coast. Small tornadoes are commoner than realised off the Sussex coast in the autumn.
A clump of Ivy on the riverside of the old railway track path south of the Toll Bridge on the east side of the River Adur at Shoreham was covered with Red Admiral Butterflies, well we counted 20 in a 2 metre square area. The most I've seen in one place this year. TQ 211 054, is about the spot, We also saw one Comma Butterfly, (it's markings were of generation 1) and 1 Clouded Yellow.
By the late afternoon the Red Admirals had restlessly settled on the large Ivy Bush in the same numbers and they were joined by a handful of Small Tortoiseshell Butterflies. This Ivy Bush was also attractive to honey bees, bubble-bees and wasps.
The unidentified Dragonfly of the last Adur Torpedo has been tentatively identified as the Common Darter (frequent 15+) Sympetrum striolatum
WILDLIFE FEATURE by Andy Horton
Cockles
Cockles from around the British Isles.
Top: the small specimen is the Lagoon Cockle, Cerastoderma glaucum.
This cockle can be found in Widewater Lagoon.
Middle: the Common Cockle, Cerastoderma edule.
Bottom: the Prickly Cockle, Acanthocardia echinata.
Look for the butterfly photographic competition.
gibbous | bs | a. LME. [Late L gibbosus, f. L gibbus hump: see -OUS.] 1 Convex, rounded, protuberant. LME. b Astron. Of the moon or a planet: having the visible disc more than half but less than fully illuminated. L17. c Bot. Very convex or bulging, esp. of solid convexities. M19. 2 Of a person or an animal: hunch-backed; having a hump. Of a part of the body: hump-shaped. LME.
1b A. S. BYATT Hethrough the window saw the irregular lump of a gibbous moon.
gibbously adv. M19. gibbousness n. (rare) L17.
antagonist | anta()nst | n. & a. L16. [Fr. antagoniste or late L antagonista (Jerome) f. Gk antagonistes, f. as next: see -IST.] A n. 1 An opponent, an adversary; an opposing force. L16. 2 Physiol. A muscle whose action counteracts that of another. Cf. AGONIST 3. L17. 3 Biochem. A substance or organism which interferes with or inhibits the action of another. Cf. AGONIST 4. L19.
1 E. GLASGOW Some have said that Nature is the antagonist of happiness. C. V. WEDGWOOD The outbreak of the second war convinced the King's more ruthless antagonists that no peace could be made while he lived.
B attrib. or as adj. = ANTAGONISTIC. Now rare. L17.
MILTON None daring to appear antagonist. COLERIDGE Antagonist forces are necessarily of the same kind.
antagonistic a. actively opposed, of the nature of an antagonist M17. antagonistical a. (rare) = ANTAGONISTIC E17. antagonistically adv. E17.
Cimmerian | smrn | n. & a. L16. [f. L Cimmerius (f. Gk Kimmerios) + -AN.] A n. 1 A member of a people fabled to live in perpetual darkness. L16. 2 A member of a nomadic people of antiquity, the earliest known inhabitants of the Crimea, who overran Asia Minor in the 7th cent. BC. L18. B adj. 1 Of or pertaining to the legendary Cimmerians; (of darkness, night, etc.) thick, gloomy. L16. 2 Of or pertaining to the nomadic Cimmerians. M19.
in Greek mythology, the river that flowed around the Earth (conceived as flat). Beyond it, to the west, were the sunless land of the Cimmerii, the country of dreams, and the entrance to the underworld. In Hesiod's Theogony, Oceanus was the son of Uranus (Heaven) and Gaea (Earth), the husband of the Titan Tethys, and father of 3,000 stream spirits and 3,000 ocean nymphs. In Homer's works he was the origin of the gods. As a common noun the word received almost the modern sense of ocean.
Excerpted from 1996 Encyclopaedia Britannica, Inc.
Under Microsoft Internet Explorer 5,
go to Internet Options/Advanced/Underline Links and click on the Hover option. Then, links will only be underlined when the cursor moves over them. This makes the web pages look tidier. Many link-heavy sites (like mine) are designed with this option in mind.
Poem of the Week DEATH AND BURIAL OF COCK ROBIN
Anonymous (later version of Mother Goose rhyme)
Who killed Cock Robin?
"I," said the Sparrow,
"With my bow and arrow,
I killed Cock Robin."
Who saw him die?
"I," said the Fly,
"With my little eye,
I saw him die."
Who caught his blood?
"I," said the Fish,
"With my little dish,
I caught his blood."
Who'll make his shroud?
"I," said the Beetle,
"With my thread and needle,
I'll make his shroud."
Who'll dig his grave?
"I," said the Owl,
"With my spade and trowel,
I'll dig his grave."
Who'll be the parson?
"I," said the Rook,
"With my little book.
I'll be the parson."
Who'll be the clerk?
"I," said the Lark,
"I'll say Amen in the dark;
I'll be the clerk."
Who'll be chief mourner?
"I," said the Dove,
"I mourn for my love;
I'll be chief mourner."
Who'll bear the torch?
"I," said the Linnet,
"I'll come in a minute,
I'll bear the torch."
Who'll sing his dirge?
"I," said the thrush,
"As I sing in the bush
I'll sing his dirge."
Who'll bear the pall?
"We," said the Wren,
"Both the cock and the hen;
We'll bear the pall."
Who'll carry his coffin?
"I," said the Kite,
"If it be in the night,
I'll carry his coffin."
Who'll toll the bell?
"I," said the Bull,
"Because I can pull,
I'll toll the bell."
All the birds of the air
Fell to sighing and sobbing
When they heard the bell toll
For poor Cock Robin.
To all it concerns,
This notice apprises,
The Sparrow's for trial,
At next bird assizes.
Submitted by Ray Hamblett
4) It is also possible just to receive a daily digest of the subject headings.
These choices can be altered at a later date. They can also be altered by me, (except for 4) if you cannot work out how to do it.
Conjectural Medieval Map of the Adur Estuary
See the web page: ancmap.htm


While the calendar may say it is spring, another winter storm threatened the East Coast on Wednesday, prompting the federal government to close down offices in the Washington, D.C. area, and canceling public events for President Donald Trump at the White House.
While there was little snow on the ground as the sun came up on Wednesday, forecasters were warning of big snow totals from the nation's capital, up the I-95 corridor through Pennsylvania and New Jersey.
But as the morning commute continued, there was little evidence in some spots of that storm.
"Total accumulation so far 1" of Salt," tweeted Rep. Billy Long (R-MO), as he documented empty streets on his commute to the U.S. Capitol, as lawmakers from the heartland subtly mocked the snow scare.
The biggest snowfall totals seemed to be to north of the Washington area, up near the Mason-Dixon line along the Maryland and Pennsylvania border, where as much as two feet of snow could fall.
But federal officials did not take any chances, as they closed government offices on Wednesday.
Despite the weather threat, Congress was in session today, though some committees had scrapped hearings set for Wednesday morning, worried about the snow.
Both the House and Senate were still going to be in session, as lawmakers were trying to finish a giant funding bill, facing a Friday night shutdown deadline.
Even with the winter weather, the Senate Intelligence Committee was forging ahead with a hearing related to Russian interference in the 2016 elections, looking at recommendations for how best to improve security measures for future elections.
At the White House, it was a snow day as well - even without any snow on the ground in the morning - as the President erred on the side of caution, and canceled two events, including a Cabinet meeting.
One thing the winter storm could not shut down was the President's Twitter feed, as Mr. Trump was up early this morning, registering his frustration with the Special Counsel probe into Russian interference in the 2016 elections, and noting his displeasure at the outcome of a case about illegal immigrants in the federal court system.


Verner Elementary's family believes that it is our school's responsibility, in cooperation with the home and community, to provide a secure and safe environment which recognizes the total child. We strive to provide every opportunity for maximum student achievement and to recognize and stimulate special talent in all students by providing a quality instructional program. We develop curriculum and teaching strategies designed to respond to the social, emotional, personal and physical well-being of each student as we assist our students in acquiring the skills necessary for life-long learning.