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Gilbert Van Hool (Antwerpen, 18 januari 1929  - Mechelen, 21 juni 2003) was een Vlaamse aquarellist en etser, die figuren, naakten, landschappen, stadsgezichten en stillevens maakte.

Biografie
Bij zijn geboorte woonden zijn ouders Ivo van Hool en Alida Lamoen in Deurne. Zijn moeder was een nicht van de bekende cabaretier Frans Lamoen en via zijn vader stamde hij af van de beeldhouwer Joannes Van Hool. In 1936 verhuisde de familie naar Bredene waar zijn vader bij de zeemacht in Oostende agent wordt voor de radiotelegrafische verbindingen. De kunstschilder Bert Hildebrandt, een goede vriend van vader Ivo, verblijft er soms gedurende weken en opent 'een andere wereld' voor de dromerige Gilbert. Later leert hij het werk van James Ensor kennen en via diens werk de mogelijkheden van de gravure.

In 1940 bij het uitbreken van de Tweede Wereldoorlog vlucht de familie naar Frankrijk, maar komt in 1941 in Brasschaat terecht. Gilbert gaat studeren aan het Koninklijk Atheneum Antwerpen, waar hij de literatuur ontdekt maar ook figuren uit de beeldende kunst zoals Vincent Van Gogh, Emiel Claus en Constant Permeke.

In 1946 begint hij studies aan de Academie van Antwerpen bij Ernest Albert. De lessen zijn vooral gericht op het werk van Rik Wouters, Henri De Braekeleer en James Ensor. Vanaf 1949 is hij voornamelijk bezig met etsen, en de graveur René De Coninck herkent zijn talent en geeft hem een diepgaande technische scholing. Hij werkt hij vooral expressionistisch, maar met allerlei experimenten tot op het abstracte af.

In 1950 wordt Gilbert Van Hool toegelaten aan het NHISKA (Nationaal Hoger Instituut voor Schone Kunsten in Antwerpen), waar hij in 1952 terecht komt bij Jos Hendrickx.

In 1960 wordt hij als laureaat gekozen uit zeventig deelnemers aan de 'Driejaarlijkse Staatsprijs voor Grafiek'. Hij verwierf ook de 'Prijs van Gouverneur Declerck'. Van 1963 tot 1994 geeft hij les aan de Koninklijke Academie voor Beeldende Kunsten te Mechelen. Hij ontvangt in 1963 ook nog de 'Prijs voor grafiek' van de gemeente Wilrijk en een bekroning op de 'Mostra di Bianco e Nero' te Lugano in Zwitserland. Tussen 1965 en 1970 geeft hij deeltijds les aan de afdeling sierkunsten aan het Rijksinstituut voor Technisch Onderwijs aan de Prins Kavellei te Brasschaat. In 1966 krijgt hij een 'Werkbeurs van het Ministerie van Nationale Opvoeding en Nederlandse Cultuur'. Van 1966 tot 1975 maakt hij 280 etsen.

De 'Accademia delle Arti del Disegno' te Florence benoemt hem tot ere-academicus en op de 'Internationale Biënnale voor Grafiek 1970', in datzelfde Florence krijgt hij de 'Gouden medaille van de Provinciale Dienst voor Toerisme' van de stad Ravenna.

In 1975 verhuisde hij naar Mechelen en schildert hij gedurende een periode van vier jaar voornamelijk aquarellen. Vanaf 1980 krijgt het etsen weer de bovenhand en de jaren 1984 tot 1986 zijn zeer productief.

Na zijn pensionering in 1994 blijft hij actief met het maken van etsen in zijn atelier en schetsen tijden zijn wandelingen. Werk van deze kunstenaar is te vinden in het prentenkabinet in Brussel.

Belgisch graficus


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Directed by: Derrick Borte
Cast: Russell Crowe, Caren Pistorius, Gabriel Bateman, Jimmi Simpson, Austin P. McKenzie
UK release: 31 July 2020
Buy from Amazon.co.uk
Performance times
This film is not currently showing in cinemas.
Russell Crowe blows his top in a ropey road rage thriller from Derrick Borte
'Russell Crowe is Unhinged!' shrieks the marketing for his latest, making it clear that an actor famed for his short temper has entered the self-parody stage of his career. Well, colour us intrigued. Playing nameless rager 'The Man', Crowe turns in a…
Russell Crowe: Unhinged reflects 'rage' in society
Film gossip
Russell Crowe believes his new film reflects the "rage" in Western society. The Oscar-winning actor stars in 'Unhinged' as The Man, who becomes hell-bent on revenge when a woman honks her horn at him while driving, and Russell feels the movie is an…
Russell Crowe found Unhinged role strange
Russell Crowe admits it was a challenge playing an unstable character in 'Unhinged'. The 'Gladiator' star plays the role of a character known as The Man in the thriller movie, who stalks a stranger following a road rage accident, and Russell admits that…
Russell Crowe's new thriller 'Unhinged' will be released in July
Russell Crowe's new thriller 'Unhinged' will be released in July. The 56-year-old actor stars in the new movie – which follows the story of a woman who gets subjected to violent case of road rage after pressing the horn at the wrong guy – produced by…
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Austin P. McKenzie
Derrick Borte
Gabriel Bateman
Jimmi Simpson
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redpajama_set_name: RedPajamaCommonCrawl


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TODAY.AZ / Business
Baku to remove special police posts set up due to lockdown
02 July 2020 [13:22] - TODAY.AZ
By Ayya Lmahamad
Special police posts established in the streets and avenues of Baku in connection with special quarantine regime will be removed as of July 2, the Interior Ministry has reported in its official website.
The reason for this is to ensure traffic intensity on inner-city roads, to attract more personnel to control the strict quarantine regime.
Moreover, this will be followed by strengthening control over city to ensure citizen's compliance with quarantine regulations, in particular the use of medical masks and maintenance social distance.
Thus, the number of patrol will be increased in streets and avenues, as well as in residential areas, and the availability of appropriate vehicle permit will be determined by means of video surveillance cameras.
Azerbaijan first introduced quarantine regime on March 24, and on June 18 decision was taken to extend special quarantine regime until August 1.
On June 18, Cabinet of Ministers announced decision to impose a two-week strict quarantine regime.
Under the new lockdown rule, citizens are allowed to leave their place of residence only after obtaining SMS permissions. Special police posts were established in the streets and avenues of the city to ensure compliance with lockdown rules.
Operation of shopping centers, restaurants, cafes, beauty salons, as well as museums, exhibition halls, sport and beaches was also suspended until July 5. Azerbaijan mandated wearing face masks on May 31.
URL: http://www.today.az/news/business/195057.html
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Discussion in 'City/Street/Architecture' started by SFTphotography, Feb 13, 2019.
I like them all but love the second, the light, the colour, the composition (I love the lines of the road and think you may have a golden spiral going on).
very nice set. all look grand, the 2nd wins out for me though. excellent lighting and exposure.


What makes a city a great place to raise a family? Our list of the top 10 best places to raise a family in US include those that have low unemployment, low crime rates, reasonable costs of living, and home prices that aren't out of the range of most Americans. Other important points, such as the best schools, plenty of parks and recreational spaces, and the potential for growth were also included in compiling this list. Which of these best places to raise a family in US are interesting to you?
Not all towns and cities are created equal. Below are some of the best cities in the United States to raise a family.
Though San Francisco is known for a very high cost of living, it pays to remember that the paychecks in the area are very high, too. The city has an inherent beauty that draws people from all over the world. It also has a great number of recreational areas, serious educational opportunities for all ages, and plenty of entertainment for anyone. If the costs are too high, keep in mind that other towns are very nearby, and you can settle down there and still take advantage of all the great things San Francisco has to offer.
This is the quintessential Southern town, filled with great food on every corner, interestingentertainment for all ages, access to some of the most beautiful natural recreational areas in the country, and a broad exposure to the arts and sciences. Thomas Jefferson called this home, and today the history is rich and clear. Keep in mind that though this is the home of a major university and only a train ride away from places like Washington D.C., Charlottesville retains a small-town feel.
Many people choose to settle here with their families. Nebraska is chosen as one of the best places to raise a family in US because it has hundreds of parks and green space to play in. The sports fields stretch as far as you can see, and the neighborhoods are full of well-tended cul-de-sacs where kids can ride their bikes without worry. Crime rates are very low, the schools are top-notch, and the jobs are readily available for hard-working parents. Costs are well below the national average, unemployment is very low, and many major companies call this area home. There is also a zoo, a huge children's theater and much more.
Though this isn't a cheap place to live, the living is very nice for the price. Stamford is home to many magnet schools that turn out productive winners in society, the crime rate is virtually nonexistent, and the idyllic setting is perfect for weekend recreation. There are big parks, easy commutes to places like NYC, and big wages for those who bring home the bacon in the family. In fact, this exclusive enclave is home to many millionaires.
This town nestled in the Hudson Valley holds the distinction of offering an amazing amount of money for education – in fact, Middletown spends more money on education than most areas in the country. It is also within an hour of Manhattan, which means parents can work in the big city but still bring up their kids in a small town. Zoos, nature centers, amusement parks, and over 34 state parks in the region make this a great place for entertainment, too.
This gorgeous town just outside of Atlanta offers a top-notch education, plenty of green space and a ridiculously low cost of living – a nice boost to those who earn a big paycheck in the metro area before making the short drive home. The schools are highly regarded, and the town makes a point of playtime for kids of all ages, with a huge fountain meant for kids to wade in and a massive public playground. Want more? The Blue Ridge Mountains and all that recreational fun are a short drive away.
Just 80 miles from Lake Michigan, this is one of the top college towns in the nation, and that higher education trickles down to the residents: more degrees, better elementary and high schools, and more educated teachers are a great draw. There is a very lively music scene, plenty of play places for the kids, green space, and festivals and activities sure to delight anyone of any age.
With a very short commute and plenty of jobs available for those who live in the area, Salt Lake City lives up to its reputation for good living. The city is astoundingly beautiful, surrounded by mountains, and the educational system is driven by some of the most prestigious universities in the country. The outdoor sports industry is huge, cultural experiences are thriving, and those who want a more religious upbringing can find it here among the many Mormons who call this city home.
A whopping 44 percent of all families here have small children, so it's no surprise that the public school system is one of the best in the nation. This enclave is home to numerous parks, plenty of green space, and all sorts of museums and other fun. The shore of Lake Michigan is just 30 minutes away, making for an easy day trip on the water. The costs of living are ultra-low, and the average paycheck is ultra-high.
The median household income might be low, but so is the cost of living, and jobs are abundant – especially in the casino industry, which pumps money into the economy. It's a huge outdoor recreation area, offering year-round play in the mountains and green spaces that have become a hallmark of this town. It has a small-town feel, but the casinos and downtown areas give it all the pizzazz of a much larger place.


Last week, the much-hyped Björk retrospective (simply titled Björk) opened at New York's Museum of Modern Art. By now, you have probably read the reviews, most of which are negative. While the show is not without flaws, its mere existence is evidence of changes within the mainstream art world in that it is a major show of a female, non-American artist presented in an untraditional manor. Taste is subjective, and if the opportunity arises to visit the exhibition, you absolutely should, because—at the very least—it is a glorious glimpse into the work of one of the most influential artists of our time. Conversely, Björk represents the difficulties an institution faces when presenting a show with an expectedly large draw.
Museum visitors are greeted in the lobby by several instruments used in Björk's Biophilia project, which is also the first app in the MoMA collection. These instruments—a gameleste, pipe organ, gravity harp, and Tesla coil—plink and plunk quietly on their own. At 9am on a Saturday, they filled the space with eclectic elevator music, but it is difficult to imagine them having a presence in the typically packed lobby.
The museum advises guests to first visit the third floor and grab a timed ticket for "Songlines", the closest thing the retrospective offers to a career timeline. It is recommended to wait for your ticketed time by visiting the "Black Lake" screening and music video theater on the second floor. Chances are that visitors will spend their time before "Songlines" waiting in a line.
At the very least, it is a glorious glimpse into the work of one of the most influential artists of our time.
Which brings us to the already infamous lines. They are a serious flaw, but they are also unavoidable based on the odd placement and labyrinthian design of the exhibition (not to mention Björk's immense popularity). Rather than using the sixth floor special exhibition galleries, the museum built a makeshift space in the atrium. As the New York Times' Roberta Smith aptly said, "The museum has certainly given more space to less." Indeed, MoMA's choice to host a huge retrospective in such small quarters seems shortsighted. Why not use the much larger MoMA PS1? Curator Klaus Biesenbach regularly presents exhibitions by big-name artists in spaces that work with their content, but why was this not the case with Björk? Simply put, Björk deserves more.
The narrative, a loosely autobiographical version of the artist's life written by Icelandic poet Sjón, is full of majestic metaphors and abstract anecdotes. While this audio experience could be quite enjoyable with closed eyes, the combination of attempting to grasp the words playing in your head, the music layered beneath those words, the words on the pages in front of you, the details of the costumes, and fellow visitors, is disorienting. At some point, you must decide what element of the experience you want to absorb the most: the visuals or the story playing in your head. It is commendable if you can do both.
"Songlines" is divided into "chambers," each representing one of Björk's eight albums. While this initially sounds promising, seeing as each period of Björk's career is a carefully curated world, the result is many rooms and very few objects. While each journal and outfit deserves to be closely examined, there is very little time or space to spend with the objects. While the rest of your time group huddles around the red sneakers from the "Hyperballad" video or the Alexander McQueen bell dress, it is easy to become distracted by the audio or feel shuffled along by other visitors. That being said, the objects on display are beautiful, such as the Hussein Calayan designed paper jacket from the Post cover, the "All Is Full of Love" robots, and of course, the swan dress.
By the end of "Songlines" the novice Björk's fan will not walk away with too much new knowledge. The wall panels offer very little context about the objects on display other than date and designer. While there is a vague sense of progression, there are very few hard facts about Björk's career or the significance of the objects being shown. This is an artistic choice, and in many ways, it was a wise choice to not add another sensory element into the already overwhelming exhibition. The MoMA's attempt to make the exhibition an immersive experience is admirable, but the lack of information makes Björk feels incomplete.
"Black Lake" is perhaps the exhibition's highlight, and says more about Björk in ten minutes than in however long it takes to wade through "Songlines". The centerpiece of Vulnicura, "Black Lake" is a reflection on her relationship with artist Matthew Barney. The video, commissioned by MoMA and directed by Andrew Thomas Huang, finds Björk exorcising her pain in a cave until she finally emerges into Iceland's green expanse healed, or at least purged (a quick flashback to a line from "Pluto": "Excuse me but I'll have to explode this body off me"). She beats her chest and drags herself over rocks on a journey to reclaim herself. Visitors watch the video in a cave of their own, a soundproofed space adorned with 6,000 felt cones. In this small room, surrounded by strangers, "Black Lake" offers each viewer a deeply personal, deeply human experience. ("Did I love you too much?") Pain is uniting, pain is personal, and few others can express it as well as Björk.


A block of Prytania Street will be restricted to a single lane of traffic for two weeks for underground repairs and repaving, officials with the city of New Orleans said, just two blocks down from another section slated to be closed for at least six more weeks.
Today, the City of New Orleans issued a traffic advisory for a travel lane closure on Prytania St. between Peniston St. and General Taylor St. to facilitate road repairs as part of the FEMA-funded Recovery Roads Program designed to restore sub-surface and roadway damages related to Hurricane Katrina.
Beginning Monday, June 15, 2015, at 7:00 a.m., the Downtown bound travel lane of the 3800 block of Prytania St., between Peniston St. and General Taylor St. will be closed to vehicular traffic. The closure will last for approximately two weeks. To minimize construction impacts, the Uptown bound travel lane will remain open. The closure will allow workers to excavate a portion of the roadway, replace the base and install pavement.
On-street parking along this travel lane closure will be prohibited at all times during construction. Construction crews will be working from 7:00 a.m. to 5:30 p.m., Monday through Friday. Work on Saturdays may occur when necessary.
Meanwhile, both lanes of the 4100 block of Prytania remain closed as a similar project continues until the end of July.
Any updates on the status of the Freret/Napoleon intersection re-opening? I thought that was supposed to happen this week.


As i already said D is better choice when starting a new code otherwise depend which size is your project.
Using D for my daily work is not an option, but I applaud thier inclusion of a "pure" attribute.
Don't put immutable with pooled.
You might make someone think pooled means the same as immutable.
Yes, immutable is not necessarily pooled, I just meant that a pooled string usually is immutable.
But for old code like has John Carmack they are no way to move that is a little too big.
Your point of useless when strings are not pooled is the best point about the string equality checks debate I ever read.
Overall, I believe the discussion about which programming language is better and specifically spending time on discussing to which extent constants or likewise should be used or not is pointless. Most programming languages are the same and the differences are mostly, in my opinion, a question of personal preference and a lot of ego.
// User inputs two strings, both are "number"
In which cases does it make sense to check if two String objects are the same object? In which of the countless cases where a comparison of two strings of characters is involved would you not be interested in testing for character equality? Why should I be forced to use something so ugly as one.equals(two)? That makes absolutely no sense. Of course, if you treat Strings as non-scalars, and if you define the equal operator to work the same on all objects, you could claim you're only being consistent. But is that intuitive? Would someone who learned that 5 == 5 is true ever think that the above example with the strings should evaluate to false? What is the point in deciding to hide away the arraylike/char pointer nature of a C "string" in introducing a proper String object in java, but then keeping the old garbage by forcing you to use an object method for comparison? How dumb is that?
There are similar examples in PHP for why intuitivity is so important, and why lack thereof makes a language so bad.
Does any language do it like this, and if not, why? Comparing by reference obviously has a speed benefit, but it's useless when the strings (or one of them) aren't pooled. Conversely, comparing by characters is needless overhead when the strings are pooled. This would to me seem to be the obvious solution.
Sometimes I wonder why don't more people use C# or Java especially since most don't write performance critical code. And since for high frequency trading some companies use Java I think that you can even choose it for performance critical code. So what's not to like? Faster development, less bugs, better debugging.... I think people choose C++ just to show off.
There are many bad or/and lazy Java and C# programers, which write slow and buggy code. I think every programer should know some assembly and C.
This is why I like D. Compared to C++/C#/Java, D gets a lot of things right.
Just adding a native unsigned 8-bit int type to java would make me happy.
I don't understand why 'byte' is signed in the first place, but it wouldn't give you much if there was such type. Every integer operation where none of the operands is a long is done in 32bit.
so it's byte + byte is converted to int + int and the result is converted back to byte.
This means you would use a little bit less space but have a more expensive operation, which is probably the reason 'byte' is signed. so byte2int and int2byte is just adding and removing bits from/to one end.
So what does "unsigned byte" do then?


Green Teachers award is organized by Society of Sustainable Development as a means to recognize and celebrate the excellence beyond education. A root of a good student is strengthened by teacher. A good student should not only excel in studies but also in discipline, humanity, social responsibility and eco friendly. The concept of Green Teacher Award is to recognize those teachers who believe in nurturing students that way. SSD takes this opportunity/pleasure to felicitate Green Teachers from your school who will be nominated by Principals. Awarded Teachers will be attending SSD seminars, workshops and events and will be also our Green Ambassadors.
You may also nominate your Green Teacher for phase II.


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Tag: Minnesota Timberwolves
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The SIP investment fund would offer a return of between 13 and 15 percent if the investment is long-term, for example, for 20 years or more. Experts say that Gold SIP also benefit this song. Comparing the SIP of gold with the SIP returns of investment funds, Kartik Jhaveri, director of wealth management at Transcend Consulting, said: "A normal SIP of investment funds would offer a return of between 13 and 15 percent if the investment is long-term, for example, for 20 years or more. Similarly, in the case of Gold SIP for more than 20 years, the same return can be expected with a margin of between 0.25 and 0.5 percent on each side of the investment.
. They are partly right and partly wrong because they are unaware of the volume of investment that their fund manager is making in those similar actions. This negative correlation makes gold an excellent hedging instrument for investors, since asset classes (gold and stocks) are negatively correlated. Agarwal suggests that retail investors should maintain exposure to gold that constitutes at least 5 to 10 percent of their investment portfolio.
Therefore, investors with inadequate exposure to gold can invest in gold, preferably through SIP in gold funds. In the event of a strong correction in gold prices, investors can invest a lump sum in gold funds based on their asset allocation strategy. This will average your investment cost and also adjust your asset mix. Investing through SIP in mutual equity funds allows investors to accumulate wealth for more than 10 years.
With investment in MF, although the risk remains high, compared to gold, the volatility and risk associated with investment are reduced in the long term. Experts say that investors who seek to create wealth and, at the same time, are willing to take a little risk and invest for the long term should invest in MF. In this case, you regularly invest a fixed amount in digital gold. Investing through SIP is a convenient option for people who do not have a demo account, necessary to invest in gold ETFs.
A SIP in gold is also more affordable because the investor can deposit a fixed amount each month according to their convenience and budget. Investing in gold through the SIP will allow you to buy gold and accumulate your wealth on a consistent basis. He adds that investors can look for alternative investment products, such as InVit or REITs, with an investment return of 8 to 9 percent with low risk. Alternatively, to provide capital protection to the investment portfolio, you can invest in mutual debt funds, bonds or bonds launched by NBFCs or in peer-to-peer (P2P) lending platforms, such as Credit Fair Capital.
The SIP, or systematic investment plan, is a service offered to investors through which they can invest fixed amounts in several funds at regular intervals. However, it is now possible to buy or invest in gold digitally through Gold Mutual Funds and a gold exchange-traded fund (ETF). Even for the remainder of fiscal year 22, investment prospects remain challenging, as the conflict between Russia and Ukraine is intensifying and the United States and China are confronted with Taiwan. Tapse believes that, when it comes to gold as an investment product, investors should consider investing between 20 and 25 percent of the investable surplus in long-term SGB bonds and in GOLD ETFs for the short and medium term trading perspective.
Those with a shorter investment horizon should stick to the fixed-income asset class, as stocks can be very volatile in the short term. For example, investors who have financial goals of 5 years or more should invest in stocks or mutual capital funds, since stocks, as an asset class, outperform fixed-income instruments by a large margin over the long term. All a person has to do is instruct the bank to automatically charge a certain amount each month, without having to worry about the hassle of losing the investment. However, investing in gold in India is different from that in other countries, since buying gold is generally more sentimental than an investment activity for Indians.
Portfolio diversification, variety of options, experience in fund management and, most importantly, the benefit of capitalization have made mutual funds a popular investment channel, especially for novice investors. Nowadays, gold funds and gold ETFs are also available in SIP mode and are also gaining ground among investors. An investor who invests in the SIP investment fund can succeed and expect to fulfill some big dream in the long term. .
FDs, SIPs, crypto, or gold? What's best investment option for women | Mint
https://www.news18.com/news/business/savings-and-investments/equities-sips-gold-fds-where-should-you-invest-now-6103255.html
Looking To Invest In Gold Through SIP? Read This
Gold funds are investment vehicles that offer exposure to gold. They come in a variety of forms, but three popular varieties are those that invest in physical gold, gold futures contracts and gold mining companies.
Although the price of gold may be volatile in the short term, it has always maintained its value over the long term. Over the years, it has served as a hedge against inflation and the erosion of major currencies and is therefore an investment worth considering.
If you're concerned about inflation and other calamities, gold can offer you a safe haven for investing. Although in the short term it can be as volatile as stocks, in the very long term, gold has maintained its value remarkably well.


text:
Taco John's:
Taco John's® Brings Bold Tastes of Mexico To Nashville
By: Taco John's | 0 Shares 51 Reads
Popular quick-service restaurant with signature menu set for Sept. 25 grand opening in La Vergne, Tenn.
September 19, 2017 // Franchising.com // NASHVILLE - Mexican food lovers in Nashville are about to discover their new favorite craving.
Popular Mexican quick-service brand Taco John's is bringing its fresh, high-quality ingredients and bold, original flavors to La Vergne, Tenn., on Monday, Sept. 25.
The rapidly growing chain based in Wyoming will open the first of several planned Nashville locations at 5068 Murfreesboro Road in La Vergne, across from the La Vergne Library, on Monday at 10 a.m. Show up early for the chance to be one of the first 100 dine-in guests on grand opening day who will receive a Golden Ticket good for a small order of Potato Olés® FREE every day for a year!
If you can't make it to Monday's grand opening, 50 Golden Tickets will also be available online. Visit Tacojohns.com/LaVergne to review the rules and enter to win.
Never had Potato Olés? Then Monday can't get here fast enough. These little slices of heaven are round bites of crunchy potato, cooked fresh and sprinkled with a signature blend of bold spices. Try dipping 'em in nacho cheese, sour cream, guacamole or salsa. You'll wonder where Taco John's has been all your life!
"If you've never been to a Taco John's, you're in for a real treat," said Larry Lavigne, co-owner of Excellent Taco, LLC, a franchisee of Taco John's. "We've assembled an awesome team and we're all proud to introduce Taco John's convenient, fast and delicious Mexican food to the Nashville area. We're looking forward to opening our doors on Monday and becoming an integral part of this community."
With its fusion of distinctive flavors and south-of-the-border spices, Taco John's menu offers several signature items, including Meat and Potato Burritos, original Street Tacos and yes, those craveable Potato Olés.
La Vergne's new Taco John's will serve breakfast until 11 a.m. The restaurant features epic daily specials like $.89 Taco Tuesday® and Wake Up Wednesday!® with $2.29 breakfast burritos. Take home a Six-Pack And A Pound® for just $11.99 any day of the week. Download the TJ® Rewards App and like Taco John's Facebook page for exclusive deals.
The new restaurant will be open Monday through Saturday from 7 a.m. to 10 p.m., and Sunday from 8 a.m. to 10 p.m. When this location opens, it will be the first Taco John's in the Nashville market and the 393rd system-wide.
About Taco John's®
Taco John's operates and franchises nearly 400 quick-service restaurants in 23 states. Privately owned, the business opened its first restaurant in 1969 in Cheyenne, WY. Taco John's prides itself on serving generous portions, menu items prepared fresh to your order, high quality ingredients and special recipes, seasonings and sauces. For more information or to apply for a position, visit tacojohns.com.
Jami Zimmerman
Champion Management
Vice President Of Public Relations
C: 469.426.7657
jzimmerman@championmgt.com
SOURCE Taco John's®
Taco John's prides itself on serving generous portions, menu items prepared fresh to your order, high quality ingredients and unapologetically original recipes, seasonings and sauces.
ADVERTISE SPONSORED CONTENT


text:
University at Buffalo statement regarding comments made by Carl Paladino
BUFFALO, N.Y. -- In the interest of public discussion on this topic, the University at Buffalo would like to present these facts:
Nearly all (99.2 percent) of UB international students enroll at UB on non-resident student visas; they cannot become residents of New York State while on a student visa, and thus they pay full non-resident tuition for all years while enrolled at UB. Tuition for out-of-state and international students covers the direct cost of their education - they do not receive discounted tuition.
The vast majority of UB's international students are focused on completing their education while in the U.S. Upon graduation they plan to return to their home countries to begin their careers.
About 5,000 international students are enrolled at UB and the university is very pleased they selected UB to pursue their education; they do not displace New York State residents. Nearly 24,000 U.S. students enroll at UB, the majority of who are from New York State.
UB's international students offer immeasurable academic and cultural value to our campuses and local communities, while making a significant economic impact to Western New York.
UB's campus community includes international students from 115 countries – enriching our campus life and creating opportunities for cross-cultural exchange.
UB's international students help make UB a great, globally minded university for all UB students by
Bringing global perspectives to UB classrooms and research labs
Helping increase cultural understanding between American students and those of other nationalities
Supporting U.S. innovation through their science and engineering coursework
Supporting programing and services on campus for all students by paying tuition at out-of-state rates
UB's international students had a total economic impact in WNY of $140,307,100 in 2013, supporting 1,943 jobs here, according to NAFSA: Association of International Educators.


text:
AskPatty Honors International Women's Day
Published Mar 7th 2014, 5:45pm by Jody DeVere in Featured Articles
International Women's Day is a global day celebrating the economic, political and social achievements of women past, present and future. The theme this year is "Inspiring Change."
The theme encourages advocacy for women's advancement everywhere in every way. It calls for challenging the status quo for women's equality and vigilance inspiring positive change.
In modern times, International Women's Day has been honored each year on March 8th. International Women's Day has been observed since in the early 1900's, a time of great expansion and turbulence in the industrialized world that saw booming population growth and the rise of radical ideologies. It is a day set aside to recognize the achievements of women that began in that turbulent period - not the least of which is the struggle for women's suffrage in this country, which began in the late 19th century and culminated in 1920 with the ratification of the nineteenth amendment.
IWD is now an official holiday in Afghanistan, Armenia, Azerbaijan, Belarus, Burkina Faso, Cambodia, China (for women only), Cuba, Georgia, Guinea-Bissau, Eritrea, Kazakhstan, Kyrgyzstan, Laos, Madagascar (for women only), Moldova, Mongolia, Montenegro, Nepal (for women only), Russia, Tajikistan, Turkmenistan, Uganda, Ukraine, Uzbekistan, Vietnam and Zambia. The tradition sees men honoring their mothers, wives, girlfriends, colleagues, with flowers and small gifts. In some countries IWD has the equivalent status of Mother's Day where children give small presents to their mothers and grandmothers.
From the International Women's Day website:
"The new millennium has witnessed a significant change and attitudinal shift in both women's and society's thoughts about women's equality and emancipation. Many from a younger generation feel that 'all the battles have been won for women' while many feminists from the 1970's know only too well the longevity and ingrained complexity of patriarchy. With more women in the boardroom, greater equality in legislative rights, and an increased critical mass of women's visibility as impressive role models in every aspect of life, one could think that women have gained true equality. The unfortunate fact is that women are still not paid equally to that of their male counterparts, women still are not present in equal numbers in business or politics, and globally women's education, health and the violence against them is worse than that of men."
Each year on March 8th, thousands of events are held throughout the world to inspire women and celebrate achievements. Take a moment to peruse the IWD website to learn a little about the history of this holiday, and the good work still being done for women worldwide. And every day, try to do your bit to ensure that the future for girls is bright, equal, safe, and rewarding.
Visit the International Women's Day website here.
For breaking news follow @womensday on Twitter or #IWD2014
Get more information on facebook/internationalwomensday
brandy schaffels, celebrate women, inspiring change, international womens day, iwd, iwd2014, womens history month


Smith-Edwards-Dunlap is the commercial printing company that not only produces high quality products but also offers superior mailing services. From pressroom to mailroom, mailing is often the last piece that completes our clients' puzzles. In addition to mail list management services, we will qualify your direct mail piece for automation postage rates.
By utilizing advanced technology in computerized addressing, presorting, and postage metering, SED complies with all United States Postal Services (USPS®) mailing requirements. Our full-time programmers process your lists to ensure accuracy and the best possible postal discounts. At Smith-Edwards-Dunlap, we take pride in being able to handle your entire list and mailing needs. We do whatever it takes to get your printed product into the right hands in the right amount of time.
Computerized addressing is an effective way to expedite the mailing process. SED's computer addressing services include deduping, file maintenance, mail qualification reports, CASS™ (coding accuracy support system), zip + 4 bar coding, and postage summary report printing. Through CASS™ we can evaluate the accuracy of your list with our address-matching software programs and improve the quality of zip-4, carrier route, and five-digit coding accuracy.


The crossing between Tunis and Salerno with Grimaldi Lines takes around 24 hours. The ferry ticket price starts at 60,00 Euro each way without car. Prices for 2 adults+2 children+car starts at approx. 580,00 Euro for both ways.
Ferry crossing from Tunis to Salerno is a very popular ferry route therefore have to be ordered months in advance!
The same goes for the Terminal in Salerno. Check-in must happen at least 4 hours before departure. The check-in office is in the Terminal, and as foot or vehicle passenger you can get your ticket here.
The vessel F/B Zeus Palace run on the route Tunis-Salerno. The vessels provides 202 air conditioned cabins, equipped with shower and WC, 151 coach seats and 1000 economy/deck seats. The Bar, self-service, "à la carte" restaurants and Videogame room, makes your trip relaxed!
Once in La Goulette follow signposting «Gare Maritime».
Foot passengers can reach La Goulette by the TGM train.


Football is a 'what have you done for me lately' kind of sport and Christopher High coach Tim Pierleoni knows it. One year after winning the Central Coast Section Division IV playoff championship, the Cougars won't only be asked to repeat their postseason performance but to survive a promotion into the new, heavy-hitting Pacific Coast League Gabilan Division.
Thick skin in football goes beyond taking hard hits and playing through pain. Football is a head game, and if the head isn't right, neither will be the body. This year expectations will be high and so will the competition. There isn't much time for reminiscing.
If the Cougars are going to thrive or survive in their new division, they'll need to rely on their seniors to lead the way. Quarterback Ben Sanford, wide receivers Joseph Cupp and Jason Scirigione, and twin-brother speedsters Tyler and Christian Davis are all together for their last high school football season.
Sanford, at 6-foot and 175 pounds, is back after throwing for 2,452 yards and 27 touchdowns in 2017, earning him a second-team Monterey Bay League all-league award and CCS honorable mention player.
Twins Tyler and Christian Davis will provide playmaking ability, with Christian at receiver/defensive back and Tyler at running back/defensive back. The Cougars hope speed does kill, as the Davis twins utilize their speed to produce big plays. They've been racing each other their whole lives, starting from minute one.
"I was born seven minutes before he was, but he's the fastest," said Christian Davis, who was second on the team with three interceptions last season.
Both Davis' play fast on game day and at practice. They don't take plays off. Effort and attitude help to make up for size, as both are 5-6 and around 160 pounds. You can't hit what you can't catch.
At wideout, the Cougars have two first team all-league standouts in Joseph Cupp and Jason Scirigione, who are both big targets at 6-2.
At Christopher High, there is one particular jersey number that stands out above the rest: No. 5, like Jake Moen, now a senior linebacker at Dartmouth College. Now Scirigione wears the honor. It's a tradition of that goes back to the Legend of 44, which was Jim Brown's number at Syracuse University.
Growing up Pierleoni moved a lot. From city to city, including Syracuse where Pierleoni played lacrosse, he eventually found his way to Gilroy, where he starred as a lineman for the Mustangs. The honored digit, the No. 5 at Christopher, goes back to his love of lacrosse, and roots in upstate New York.
The Cougars will depend on youth on both offensive and defensive lines. Pierleoni will also break in three or four new linebackers.
Alisal, Watsonville, Monterey, North Monterey County, and Pajaro Valley High are out and replaced with Aptos, Alvarez, Salinas, Palma, San Benito and Seaside. Gilroy High, owners of its own CCS Championship, remains.
Numbers say a lot, too. Christopher's departing conference foes won 11 games, compared to the 40 wins for its new division mates.
Salinas (11-3, 7-0) won the CIF Central Coast Section Open Division 1 Championship, and later advanced to the Regional Finals in the CIF Division 4AA Playoffs where they lost to Placer High School, 43-42.
Pierleoni, who is in his 34th year in coaching was unloading beer trucks in the fall of 1985 at 3 a.m. when he was asked by a co-worker, who happened to be a coach at Pleasant Valley High, to come out to help with practice. After one day back on the field, football hooked him again.
After high school, Pierleoni played linebacker at Gavilan College and Cal State Hayward, now California State University East Bay.
Old school former high school football veterans may not recognize conditioning drills in new high school ball. Two-a-days are a thing of the past, too. Pierleoni, however, believes that a well-conditioned team wins in the fourth quarter.
Being a football player isn't easy. When your friends are going home, eating Lucky Charms, playing video games, and hanging out with friends, you're out on the field, in the heat, working hard, on and off the field, including the weight room. That includes work in the classroom.
Numbers are a concern for the Cougars. Since Gilroy has two high schools, the pool of available players is split between the two schools, unlike at San Benito High, which is the only game in town. Because of this, freshmen and the junior varsity will see a lot of time together.
8/24 at Monte Vista Christian, 7:30 p.m.
8/31 vs. Live Oak, 7:30 p.m.
9/14 at King City, 7:30 p.m.
9/21 at Seaside, 7:30 p.m.
9/28 vs. Hollister, 7:30 p.m.
10/5 vs. Salinas, 7:30 p.m.
10/12 at Palma, 7:30 p.m.
10/19 vs. Aptos, 7:30 p.m.
10/26 vs. Alvarez, 7:30 p.m.
11/2 at Gilroy, 7:30 p.m.


text:
Mel B says James Corden is one of the 'biggest d***heads' in showbiz
By Jafar Sadhik On Dec 3, 2022
Mel B, 47, has been making headlines with her recent interview mishaps and outspoken personality, with her recent interview on the Big Narstie Show being no different. The Spice Girls star was asked to name the "biggest d***head" in showbiz, with Mel using the opportunity to blast James Corden as "not being very nice".
Mel appears on this evening's The Big Narstie Show, with Mo Gilligan and Big Narstie hosting.
Mo asked the Spice Girl: "Who is the biggest d***head celebrity you've ever met?"
Mel shockingly replied: "So, there's a few. James Corden, Geri Halliwell, Jessie J and me!"
Big Narstie interjected: "You said James Corsden, what did he do?"
READ MORE: Piers Morgan rages at Meghan and Harry's 'unforgivable PR war'
Mel B replied: "I think you always have to be nice to the people that you work with whether it be production, camera guys, sound, lighting – we all work for the same thing.
"So you should always be nice and he hasn't been very nice."
This isn't the first time James has been criticised this year, with restaurant owner Keith McNally calling out the presenter for his comments to his workers at the Balthazar on two occasions.
Keith took to Instagram to claim James was one of the "most abusive customers" he ever had in his restaurant.
James was banned from the restaurant chain, after admitting at first that he believed he did "nothing wrong".
However, after the public scrutiny the presenter received, he admitted that he made a "rude, rude comment" adding that it was "never my intention" to upset the staff at the restaurant.
He said on The Late Late Show: "I didn't shout or scream, I didn't get up out of my seat, I didn't call anyone names or use derogatory language.
"But the truth is I have made a rude, rude comment. And it was wrong. It was an unnecessary comment, it was ungracious to the server."
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The restaurant owner, following James' apology on The Late Late Show, lifted the restaurant ban.
James even said on the show that after the Instagram post he contacted the restaurant host "immediately" and they had a "good talk".
He continued: "He appreciated the call. I was happy that we got to clear the air. And I felt like we dealt with it privately… but by this point, the story was out there and more people were upset."
James spoke about the incident to The Times, with him reiterating that he didn't "shout or scream", but this did not please the restaurateur.
He wrote on Instagram that the Gavin and Stacey star had "flip-flopped" and told a "massive lie" again.
Keith wrote: "On second viewing, I found his TV "confessional" contrived and phony. The actor will say anything to save his bacon.
"In the scheme of things my opinion means nothing, but after Friday's interview and a second look at his fraudulent confessional, I've given up on James Corden. For Good."
Express.co.uk have contacted James Corden for comment previously.
The Big Narstie Show is on Channel 4 tonight at 11:05pm
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Jafar Sadhik 27274 posts
A passionate digital marketer possessing sound knowledge in the fields like SaaS tools, CX, churn statistics, etc. Previously, worked for top ventures like SportsKeeda and Neil Patel Digital India, and currently works at SmartKarrot Inc. He loves to read books during leisure and a great admirer of Agatha Christie's works.
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text:
Q: How to extract these data items from JSON file? I have a JSON file and I would like to get 'id' value and 'key' value for each champion:
Here example with 2 champions of my champion.json file, but if I have 100 champions how can I do that?
{
    "type": "champion",
    "format": "standAloneComplex",
    "version": "9.23.1",
    "data": {
        "Aatrox": {
            "version": "9.23.1",
            "id": "Aatrox",
            "key": "266",
            "name": "Aatrox",
            "title": "the Darkin Blade"
        },
        "Ahri": {
            "version": "9.23.1",
            "id": "Ahri",
            "key": "103",
            "name": "Ahri",
            "title": "the Nine-Tailed Fox"
        }
    }
}

My python file :
import json

all_data = open('champion.json',  encoding="utf8")
data_champ = json.load(all_data)

for element in data_champ['data']:
    print(data_champ[element]["key"])
    print(data_champ[element]['id'])

A: In the structure of the JSON data in your question, the value associated with the data key is a dictionary-of-dictionaries, so you would need to access the value of each one of them like this:
import json

with open('champion.json',  encoding="utf8") as all_data:
    data_champ = json.load(all_data)

for value in data_champ['data'].values():
    print(value["key"])
    print(value['id'])

Output:
266
Aatrox
103
Ahri

I also changed the file handling to ensure it gets closed properly by using a with statement.

redpajama_set_name: RedPajamaStackExchange


If you demand luxury and comfort, our gorgeous Phoenix West II condominium home in Orange Beach Alabama will exceed your expectations. Phoenix West II, overlooking the Gulf of Mexico one of a kind resort has the largest indoor pool in Orange Beach, state of the art fitness facility, tennis court, 6 hot tubs, sauna, outdoor pool, indoor pool and the famous lazy river, all on the white-sand beaches of the Alabama Gulf Coast. The master bedroom in this Orange Beach vacation rental by owner has a king size bed and a jetted 2 person tub in the master bath plus a walk in shower and double-vanity. The second bedroom includes two queen beds, and an adjoining bath. The third bedroom has a queen bed, also with a private bath. There is a 4th bathroom in the hallway, that includes a clothes washer/dryer. This gulf-front Phoenix West condo can accommodate up to 10 people. Plan your escape to Orange Beach, relax in the spacious private balcony overlooking the Gulf of Mexico, with adequate seating for family & friends. Play tennis, spend a care-free afternoon on the lazy river, or sooth you muscles in a Jacuzzi. The gourmet kitchen has stainless steel appliances, granite counter-tops and custom cabinetry. The dining area features a wet bar with ice maker, making entertainment a breeze.
Orange Beach Alabama has a year-round mild climate and is a popular family beach vacation destination on the Gulf Coast, the area offers an array of activities such as dolphin cruises, championship golf courses, charter fishing and nature hikes. Choose from national hotels, camping or a variety of beach accommodations from private vacation rentals property management companies with huge inventories. There are numerous options for nightlife, from family entertainment to rocking roadhouses, enjoy your pick of plays, free concerts, dancing or just listening to a variety of musical genre. Enjoy the freshest seafood available at the numerous Orange Beach restaurants featuring fine-dining to laid-back local favorites.


text:
#ifndef ALIGENPERFORMANCE_H
#define ALIGENPERFORMANCE_H

// Perormance generator for Jet  according generic functions
//
//  TF1 *   fF1Momentum;           // momentum distribution function inGeV
//  TF1 *   fFPhi;                // phi distribution function in rad
//  TF1 *   fFTheta;              // theta distribution function in rad
//  TF3 *   fFPosition;           // position distribution function in cm
//  TF1 *   fFPdg;                // pdg distribution function
//  We assume that the moment, postion and PDG code of particles are independent
//  Only tracks/particle crossing the reference radius at given z range
//
// Origin: marian.ivanov@cern.ch

#include "AliGenerator.h"
class TF3;
class TTreeSRedirector;
class TChain;

class AliGenPerformance : public AliGenerator{
public:
  enum EStreamFlags{ //
    kFastOnly          =0x00001,    // flag: fast MC without stack for tests
    kStream            =0x00002,    // flag: for streaming
    kStreamEvent       =0x00004     // flag: make key after each event - for debugging in case of job failure
  };
  AliGenPerformance();
  AliGenPerformance(const char* generName,Int_t debugLevel);
  AliGenPerformance(const AliGenPerformance& perf);
  AliGenPerformance &operator=(const AliGenPerformance& perf);
  virtual ~AliGenPerformance();
  virtual void Generate();
  virtual void Init();
  void SetNJets(Double_t nJets){fNJets=nJets;}
  Double_t GetNJets()const {return fNJets;}
  void SetFunctions(TF1 * momentum, TF1 *fphi=0, TF1 *ftheta=0, TF3 * position=0, TF1* pdg=0);
  void SetStreamer(TTreeSRedirector *pcstream){fStreamer=pcstream;}
  TTreeSRedirector * GetStreamer(){return fStreamer;}
  static void TestAliGenPerformance(Int_t nEvents, TF1 *f1pt, TF1 *fpdg);
  static TChain *  MakeKineChain();
private:
  Float_t fNJets;                 // mean number of jets
  TF1 *   fF1Momentum;            // momentum distribution function
  TF1 *   fFPhi;                  // phi distribution function
  TF1 *   fFTheta;                // theta distribution function
  TF3 *   fFPosition;             // position distribution function
  TF1 *   fFPdg;                  // pdg distribution function
  TTreeSRedirector *fStreamer;    // ! test stream
  Int_t   fVerboseLevel;          // verbose level
  //
  ClassDef(AliGenPerformance,1) // performance generator
};

#endif

redpajama_set_name: RedPajamaGithub


text:
The human herpesvirus, a potential trigger for Alzheimer's Disease?
The mere thought that you could develop a progressive and irreversible disorder of the brain, like that of Alzheimer's disease, may fill you with some degree of fear.
When you've led a self-sufficient lifestyle throughout your adult years, any progressive deterioration in the ability to think clearly, remember details and function accordingly during older age is unnerving. No one wishes to develop such a condition, nor see a loved one through it…
As yet, there is no cure for Alzheimer's disease on the horizon, and as such, finding one is part of ongoing research. Every so often, updated study findings surface, and medical researchers and professionals are able to learn a little more about this complex medical condition. Clues, ideas and potential influences all filter through a significantly funded research process. The goal is to better understand the highly intricate nature of this disease so as to possibly diagnose it sooner and develop more effective treatment processes.
The condition is characterised by many complex changes in the brain, but scientists do not yet have a clear understanding of the direct causes of the disease. The development of Alzheimer's is largely attributed to the accumulation of amyloid proteins and sticky plaques in the brain which contribute to the deterioration of brain cells that influences the progressive decline of cognitive function. There is still a great deal to learn about the disease, including its causes and associated triggers if any further medical advancements are to be made.
The latest study, published in the journal, Neuron on 21 June 2018, highlights a potential connection between the development of Alzheimer's disease and certain strains of the human herpesvirus – the HHV-6A and HHV-7 strains to be more precise. Through their analysis, researchers noted that the brain tissues of individuals with diagnosed Alzheimer's disease appeared to have levels of these strains that were considerably higher compared to those without the condition. (1)
The team consisted of researchers from the Arizona State University's Banner Neurodegenerative Disease Research Center, as well as the Icahn School of Medicine at Mount Sinai (New York) in the USA. Their findings detail an interesting association which will surely invite further study down the line.
For now, what could this study potentially mean for those with the condition?
As a form of dementia, Alzheimer's is estimated to affect between 60% and 70% of individuals diagnosed with this type of condition around the world. Approximately 50 million people are believed to be living with some form of dementia across the globe. (2) With such a high prevalence, it's not surprising that brain disorders, like dementia / Alzheimer's disease are being so thoroughly researched.
If the human herpesvirus plays a significant role in the development of Alzheimer's, surely then treatment procedures could be adapted to get the better of the disease? After all the use of established antiviral medications can be effective in treating virally triggered immune cascade reactions – a factor which can stimulate the growth of amyloid proteins and plaques.
If this is the case, could Alzheimer's then possibly be prevented? Infection with the human herpesvirus would have to be a proven cause of the degenerative disease, and this is where current research questions are being focussed. Merely identifying a viral presence isn't an answer in itself. A clue in this regard may lie in attaining a better understanding of the associated herpesviruses, and whether or not their presence in the brain is directly linked to the development of Alzheimer's disease.
What are herpesviruses?
There are more than 100 known herpesvirus strains. Of these at least 8 infect human beings, many of which are actually quite common. (3) These include:
Herpes simplex virus – type 1 (oral herpes)
Herpes simplex virus - type 2 (genital herpes)
Varicella-zoster virus (known to cause chickenpox and shingles)
Kaposi's sarcoma-associated virus (also referred to as the human herpesvirus 8)
Human herpesvirus 6 (A and B)
Human herpesvirus 7
Herpesviruses are structured in unique layers which contain double-stranded DNA. The genes of these viruses replicate in a specific order, eventually allowing virus particles (virions) to be transported to cell membranes. As these released virus particles mature, the host's (an infected person's) cells perish.
The virus particles may also exist within the body in a latent state, making the virus inactive for a period of time. Symptomatic manifestations can arise causing illness (due to an active infection) and then become dormant for some time (i.e. months or even years). A latent herpes virus can reactivate at any particular time during a person's lifetime. While this is an expected mechanism of a virus, the precise underlying reasons as to why this occurs are not very well understood. In the case of the herpes simplex viruses, certain stimuli do appear to trigger viral reactivations – these include stress, exposure to ultraviolet light and even menstruation – but such triggers aren't well defined as a possible causal link.
Herpesviruses are classified into one of three sub-family groupings – alpha herpesviruses, beta herpesviruses and gamma herpesviruses. Human herpesviruses 6 and 7 are generally considered gamma herpesviruses, however they also display host range mechanisms (i.e. the ability to infect certain cells within the host) of beta herpesviruses. Gamma herpesviruses characteristically have a more limited host range.
Herpesvirus strain groupings which have a short replicative cycle (or reproductive cycle) include 'A', herpes simplex viruses (1 and 2) and the varicella-zoster virus. Cytomegalovirus, 'B' herpesvirus and human herpesvirus 6 and 7 tend to have a longer replicative cycle. Viruses with short cycles typically have a broad host range (i.e. the ability to infect and reproduce in a wide variety of organisms or cells), while longer cycles have a host range that is more restricted. Other host range herpesviruses that are restricted include the human herpesvirus 8 and Epstein-Barr virus.
Short cycles mean that virus particles are able to destroy host cells within hours. Longer cycles mean that this mechanism of infection takes place over a period of days.
Human herpesvirus 6 is more commonly associated with kidney transplant rejection, acute liver impairment or failure and infections affecting the central nervous system. Herpesvirus 6 is also associated with the development of roseola, a mild infection affecting young children resulting in a high fever and rash (also referred to as sixth disease).
Although the mode of transmission for herpesviruses 6 and 7 is not very well defined, it is agreed that most human beings appear to have a high prevalence of antibodies to these viruses very early on in life. (4) This suggests that the majority of human beings are thus exposed to these viruses at some stage during early life. Aspirated / inhaled viral secretions (also referred to as oropharyngeal secretions) are believed to be experienced in the home which may be one reason why antibodies are so high from a young age. Viral particles are transmitted via a host with a compromised immune system. This is yet to be sufficiently documented, however.
To date there is no official therapy for infections with herpesvirus 6 and 7. Most medical doctors who have detected these viruses in a patient may implement antiviral treatment (where necessary – i.e. where severe signs of infection occur) commonly used for cytomegalovirus since it is considered to be closely related, and thus the most effective agent to help clear an active virus.
In terms of prevention, there is only one licensed vaccine, and this is targeted to protect against the varicella-zoster virus in high-risk population categories.
How were herpesviruses identified in relation to Alzheimer's disease?
The U.S. research team, with permission from the National Institutes of Health (who provided the donor samples and other data), initially set out to analyse post mortem brain tissue samples comparing those with diagnosed Alzheimer's disease to others without the condition. The team analysed more than 600 post mortem brain tissue samples (from diagnosed Alzheimer's disease patients) donated for research and more than 300 from non-dementia individuals (i.e. those with no neurological signs of brain disorder).
The team intended to assess 6 key regions within the brain, merely to see if there were any comparable differences, and if there were, to explore them further. The team assessed brain regions that experience changes resulting in early indications of Alzheimer's disease, comparing these with those that develop more profound neuronal reductions later on. The purpose was to better understand the dramatic changes a patient experiences during progressed stages of the illness so as to help identify any possible ways treatment for the condition could be enhanced for both current and future patients.
"We were looking for genes that changed during the progression of Alzheimer's disease, especially ones that changed most dramatically," says Dr Samuel Gandy who is the associate director of the Mount Sinai Alzheimer's Disease Research Center, as well as a professor of neurology and psychiatry at the Icahn School of Medicine at Mount Sinai.
The team may not necessarily have expected to identify a viral connection, but this was the most significant difference that there was to be found. It's not the first time, however, that herpesviruses have been linked with Alzheimer's. Quite a few past studies have noted at least one of the human infecting varieties, and HHV 6 (A and B) has featured in some capacity or another too. (5) The herpes simplex viruses and cytomegalovirus varieties have featured more prominently in previous studies. Now HHV 6A and 7 have a spotlight cast over them.
The research team conducted a DNA (deoxyribonucleic acid) sequencing process and were able to determine detailed profiles of all inherited genes in the donor samples (whether diseased and not). The team then looked at RNA (ribonucleic acid) in order to identify and detail gene expression for each donor sample. From there, they made use of laser-captured neuronal gene expression data and clinical assessments for each sample of Alzheimer's donors so as to best determine the nature of cognitive dysfunction during life. The team also made use of post mortem neuropathologic assessments in order to identify the severity range of amyloid protein tangles and plaques which are characteristic of the disease.
When looking at the identified genes of each participant, the team noted that human herpesviruses 6A (HHV 6A) and 7 featured fairly prominently. This viral presence may have a role in regulating the expression of DNA genes, including some of those considered high risk for Alzheimer's disease and which are involved in the processing mechanisms of amyloid protein accumulation.
Viral levels appeared to be most prominent within the areas of the brain where Alzheimer's disease is likely to have developed. These levels were not as high in non-disease sample donors. Human herpesviruses 6A and 7 appeared to be most prominent in the superior temporal gyrus (the primary auditory cortex which processes sounds and an area responsible for multisensory integration) and anterior prefrontal cortex (and area where complex planning and problem-solving functions take place) regions of the Alzheimer's disease brain tissue samples.
"When you look at the viral genes in the setting of the network they're connected to, they often regulate the expression of genes we think are related to Alzheimer's disease," Dr Gandy adds.
The levels of the virus detected in the brain tissue samples also appeared to correlate with the last recorded clinical dementia ratings (a score that is performed by a medical doctor quantifying the severity of a person's symptoms) before death. These ratings detail both neurological evidence (obtained through testing) and behavioural symptoms noted during follow-up consultations. Those with higher viral DNA in the brain appeared to have more severe symptoms prior to their demise.
Thus, the research team began to question whether the development of Alzheimer's disease could potentially be the result of the brain's response to the presence of HHV 6A and 7 in the body. That said, they're not jumping to conclusions and are certainly not concluding that herpesviruses are by any means a primary cause of Alzheimer's disease development.
Higher viral DNA in the brain does, however, appear to have some role in the neuro-networks which directly influence the development of the disease. It therefore may be a contributing factor, either with regards to disease development or the progression rate, although this requires further and more detailed research. It's possible that (potentially latent or reactivated) herpesviruses either activate genes that are in close proximity to those that influence Alzheimer's development or suppress them.
Further research is needed to determine whether high levels of herpesviruses cause an immune or inflammatory reaction which could potentially spark Alzheimer's development, or if their presence in the brain is more so as a result of the organ being unable to defend itself from an altogether different dysfunction. Whether herpesviruses are a direct cause or a secondary complication of sorts, theoretically antiviral treatment should be a viable option for treatment. It's worth investigating further.
Clinical trials (small and larger population groups) using antiviral medications may very well be on the cards to determine if such treatment could inhibit the production of herpesvirus strains. Researchers can now assess the blood, spinal fluid and other bodily fluids of living diagnosed patients to determine the potential presence of herpesvirus strains. If these are present, testing and research analysis can be applied so as to ascertain whether a favourable treatment outcome may be possible.
Should further research be able to determine a more precise causative link, antiviral medications which are already fairly effective for treatment could then be very useful for affected Alzheimer's patients. To what extent? Well, more analysis will need to be done in order to define this. If a direct causative link is not relevant however, what role could herpesviruses actually play then? Research will need to determine this too. There is still a human genetic and viral question mark lingering about for which a precise answer is not yet entirely clear.
For a disease with highly complex development and progression mechanisms, being able to determine anything specific is a major feat. If herpesviruses do indeed play a significant role in the development of Alzheimer's, this team of researchers may just have opened a door to a potentially crucial breakthrough in medical science. It's not entirely certain just what drives the long-term progression of brain changes or cognitive dysfunction, but such research has tapped into 'a little something' that surely paves a new path for further exploration with regards to precise causative mechanisms.
Certainly, the presence of viral DNA is significant, and in theory, should give way to potentially crucial advancements. The precise impact of these viruses can now be analysed further in future experimental studies. This will be helpful in determining implications as they apply to effective treatment, and even, possibly, prevention of the condition. This research doesn't significantly shorten the path in this regard, but it does enable more specific details to be included in research conducted in future.
In a sense, herpesviruses may just be another puzzle piece. At this stage, there are more questions than answers and research will investigate the direct relation between herpesviruses and Alzheimer's disease, whether causal or not – it could be that those prone to developing Alzheimer's are actually just more susceptible to acquiring viruses.
With each new piece of information, a clearer picture of what causes Alzheimer's disease is being built up. The ultimate answer could potentially lead to the kind of treatment advancements every specialist in this area of expertise, those affected by the condition and their loved ones would ultimately like to see.
Until then, we look forward to more research findings…
1. Neuron. 21 June 2018. Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus: https://www.cell.com/neuron/fulltext/S0896-6273(18)30421-5 [Accessed 26.06.2018]
2. World Health Organization. December 2017. Dementia Fact Sheet: http://www.who.int/news-room/fact-sheets/detail/dementia [Accessed 26.06.2018]
3. National Center for Biotechnology Information (NCBI). 1996. Medical Microbiology. 4th edition. Chapter 68 - Herpesviruses: https://www.ncbi.nlm.nih.gov/books/NBK8157/ [Accessed 26.06.2018]
4. US National Library of Medicine - National Institutes of Health. March 2002. Neutralizing Antibody Responses to Human Herpesviruses 6 and 7 Do Not Cross-React with Each Other, and Maternal Neutralizing Antibodies Contribute to Sequential Infection with These Viruses in Childhood: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC119946/ [Accessed 27.06.2018]
5. US National Library of Medicine - National Institutes of Health. July 2002.Herpesviruses in brain and Alzheimer's disease: https://www.ncbi.nlm.nih.gov/pubmed/12115887 [Accessed 26.06.2018]


text:
EPSRC Reference: EP/T021063/1
Title: COG-MHEAR: Towards cognitively-inspired 5G-IoT enabled, multi-modal Hearing Aids
Principal Investigator: Hussain, Professor A
Renals, Professor S Hart, Professor E Casson, Dr A
Adeel, Dr A Al-Dubai, Professor AY Bell, Dr PJ
Sellathurai, Professor M Arslan, Professor T Buchanan, Professor WJ
Abbasi, Dr Q Imran, Professor MA Akeroyd, Professor M
Baillie, Professor L Ratnarajah, Professor T
Alpha Data Parallel Systems Ltd (UK) deafscotland Digital Health and Care Institute
NHS Nokia RNID (Royal Natnl Inst for Deaf People)
Sonova AG The Data Lab UCL
University of Manchester, The
Department: School of Computing
Organisation: Edinburgh Napier University
Starts: 01 March 2021 Ends: 28 February 2025 Value (£): 3,259,000
Biomechanics & Rehabilitation Cognitive Science Appl. in ICT
Med.Instrument.Device& Equip.
Currently, only 40% of people who could benefit from Hearing Aids (HAs) have them, and most people who have HA devices don't use them often enough. There is social stigma around using visible HAs ('fear of looking old'), they require a lot of conscious effort to concentrate on different sounds and speakers, and only limited use is made of speech enhancement - making the spoken words (which are often the most important aspect of hearing to people) easier to distinguish. It is not enough just to make everything louder!
To transform hearing care by 2050, we aim to completely re-think the way HAs are designed. Our transformative approach - for the first time - draws on the cognitive principles of normal hearing. Listeners naturally combine information from both their ears and eyes: we use our eyes to help us hear. We will create "multi-modal" aids which not only amplify sounds but contextually use simultaneously collected information from a range of sensors to improve speech intelligibility. For example, a large amount of information about the words said by a person is conveyed in visual information, in the movements of the speaker's lips, hand gestures, and similar. This is ignored by current commercial HAs and could be fed into the speech enhancement process. We can also use wearable sensors (embedded within the HA itself) to estimate listening effort and its impact on the person, and use this to tell whether the speech enhancement process is actually helping or not.
Creating these multi-modal "audio-visual" HAs raises many formidable technical challenges which need to be tackled holistically. Making use of lip movements traditionally requires a video camera filming the speaker, which introduces privacy questions. We can overcome some of these questions by encrypting the data as soon as it is collected, and we will pioneer new approaches for processing and understanding the video data while it stays encrypted. We aim to never access the raw video data, but still to use it as a useful source of information. To complement this, we will also investigate methods for remote lip reading without using a video feed, instead exploring the use of radio signals for remote monitoring.
Adding in these new sensors and the processing that is required to make sense of the data produced will place a significant additional power and miniaturization burden on the HA device. We will need to make our sophisticated visual and sound processing algorithms operate with minimum power and minimum delay, and will achieve this by making dedicated hardware implementations, accelerating the key processing steps. In the long term, we aim for all processing to be done in the HA itself - keeping data local to the person for privacy. In the shorter term, some processing will need to be done in the cloud (as it is too power intensive) and we will create new very low latency (<10ms) interfaces to cloud infrastructure to avoid delays between when a word is "seen" being spoken and when it is heard. We also plan to utilize advances in flexible electronics (e-skin) and antenna design to make the overall unit as small, discreet and usable as possible.
Participatory design and co-production with HA manufacturers, clinicians and end-users will be central to all of the above, guiding all of the decisions made in terms of design, prioritisation and form factor. Our strong User Group, which includes Sonova, Nokia/Bell Labs, Deaf Scotland and Action on Hearing Loss will serve to maximise the impact of our ambitious research programme. The outcomes of our work will be fully integrated, software and hardware prototypes, that will be clinically evaluated using listening and intelligibility tests with hearing-impaired volunteers in a range of modern noisy reverberant environments. The success of our ambitious vision will be measured in terms of how the fundamental advancements posited by our demonstrator programme will reshape the HA landscape over the next decade.
Organisation Website: http://www.napier.ac.uk


The rent at Royal Arms of Bowling Green Apartments ranges from $600 for a one bedroom to a $990 three bedroom. Apartments in this building are about 5% less expensive than the Bowling Green average. This is a pet-friendly apartment.
This apartment is in Bowling Green. The closest park is Pioneer Park.
Royal Arms of Bowling Green Apartments has a Walk Score of 59 out of 100. This location is Somewhat Walkable so some errands can be accomplished on foot.
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View all Bowling Green apartments on a map.
Royal Arms of Bowling Green Apartments is in the city of Bowling Green, KY. Bowling Green has an average Walk Score of 37 and has 58,067 residents.


text:
namespace base {

// TODO(erikkay): does it make sense to support PLATFORM_FILE_EXCLUSIVE_* here?
PlatformFile CreatePlatformFile(const std::wstring& name,
                                int flags,
                                bool* created) {
  int open_flags = 0;
  if (flags & PLATFORM_FILE_CREATE)
    open_flags = O_CREAT | O_EXCL;

  if (flags & PLATFORM_FILE_CREATE_ALWAYS) {
    DCHECK(!open_flags);
    open_flags = O_CREAT | O_TRUNC;
  }

  if (!open_flags && !(flags & PLATFORM_FILE_OPEN) &&
      !(flags & PLATFORM_FILE_OPEN_ALWAYS)) {
    NOTREACHED();
    errno = ENOTSUP;
    return kInvalidPlatformFileValue;
  }

  if (flags & PLATFORM_FILE_WRITE && flags & PLATFORM_FILE_READ) {
    open_flags |= O_RDWR;
  } else if (flags & PLATFORM_FILE_WRITE) {
    open_flags |= O_WRONLY;
  } else if (!(flags & PLATFORM_FILE_READ)) {
    NOTREACHED();
  }

  DCHECK(O_RDONLY == 0);

  int descriptor = open(WideToUTF8(name).c_str(), open_flags,
                        S_IRUSR | S_IWUSR);

  if (flags & PLATFORM_FILE_OPEN_ALWAYS) {
    if (descriptor > 0) {
      if (created)
        *created = false;
    } else {
      open_flags |= O_CREAT;
      descriptor = open(WideToUTF8(name).c_str(), open_flags,
                        S_IRUSR | S_IWUSR);
      if (created && descriptor > 0)
        *created = true;
    }
  }

  return descriptor;
}

}  // namespace base


text:
JAMES HAMILTON "JIM" SHAND (1890-1956)
RACHEL HARRIET THOMAS (1885-1922)
ELEANOR FLORENCE MAYO (1897-1965)
(Last Updated: November 30, 2013)
James Hamilton "Jim" SHAND was born Apr 17, 1890 in Jamaica Plain (near Boston), Massachusetts, USA, the eldest son of Agnes KAYE & Thomas SHAND (1868-1915). Jim's father, a Carpenter, was born and raised in Hebbville, Nova Scotia (south of Bridgewater); had met and married his mother in the Boston area where Jim and his brother Tom were born and where they lived until 1894 when the young family moved to Nova Scotia, the home province of his father.
MORE ABOUT THOMAS SHAND
In 1894 Jim's family returned to Nova Scotia where his father continued to worked itinerantly as a carpenter and where two more brothers were born; Wally and Joe in Lunenburg and Halifax respectively.
Jim was 10 years old in 1900 when the family settled in Glace Bay on Cape Breton Island where they remained for the next 10 years as Jim grew into manhood.
In the Census of 1911 at Glace Bay, Jim was recorded as age 21, a shift-man working in a Coal Mine with his brothers Tom & Walter.
Brothers & Parents Part Ways
Jim & Joe move to Winnipeg
Around 1912 it seems Jim's parents decided to go their separate ways. His mother (Agnes) returned to the Boston area (Keene, New Hampshire) where she probably had relatives, taking brothers Tom & Wally with her. They would remain there the rest of their lives.
Jim and his 16 year old brother Joe chose to remain with their father (Tom Sr.) who decided to move to Winnipeg, Manitoba. The three of them found work there as carpenters, probably a family enterprise.
The Outbreak of World War I
On Aug 14, 1914 Great Britain declared war on Germany and Austria-Hungary to uphold treaties with France and Belgium which were under German attack. We don't know exactly when or where Jim's father (Tom Sr.) enlisted, but when he did, it would be the last time Jim would see his father. What we do know is that he died as a soldier at sea in 1915.
Jim & Rachel (nee THOMAS) SQUIRREL
Around 1914 Jim would have been about 23 years old when he met and began a connubial relationship with 28 year old Rachel (nee THOMAS) SQUIRREL in Winnipeg. Rachel was a Treaty Indian, estranged from her former husband, Percy SQUIRREL aka WILLIAMS, also a Treaty Indian who was living in St Peters Parish, north of Selkirk.
** MORE ABOUT PERCY SQUIRREL
Rachel THOMAS was born around 1885, daughter of Mary Ann STEVENS & William THOMAS (1846-1931) of St Peters Parish. ** MORE ABOUT WILLIAM THOMAS
In 1901, as a 16 year old she had become the wife of Percy SQUIRREL in what was then still the St Peters Indian Reserve. After having two children with SQUIRREL (both died in infancy), she left him and moved to Winnipeg, perhaps around 1905. This of course all occurred while the St Peters Indian Band was still intact; it wasn't until about 1908 that the band was relocated to the Fisher River area. SQUIRREL would later (1923) re-marry to Clara FAVEL.
In 1907-08 many Indian families of the former St Peters Reserve were displaced by greedy white land speculators during the relocation of band to Fisher River in 1907-08. Many of those displaced, but who for various reasons could not, or who simply didn't want to move to Fisher River, chose instead to move to what would become Winnipeg's notorious 'north-end slums'.
Fairford, Manitoba
Location of Jim Shand's farmstead
It is said that in March of 1915, Jim applied for a homestead on SE-6-31-9-W1 at Fairford, MB. I have searched the Western Land Grants, but found no record of such a grant. I can only guess that it was not a homestead grant it may have been simply a purchase. His first child with Rachel was Raymond, born on Aug 15, 1915, and they appear to have been on the land at Fairford by November 15 that year, eager to establish a home for themselves there.
In 1915 news of their soldier father's death at sea reached Jim & Joe, and on Oct 16 that year Joe enlisted in the Canadian Over-seas Expeditionary Force at Winnipeg. He would be gone until the war ended in 1918.
In May of 1916 a fire destroyed Jim's Fairford home, and the family went back to Winnipeg, where Jim worked as a Carpenter so he could raise money, determined that he would start again. Returning in November, he rebuilt his house and attempted to resume clearing and fencing the land. This meant the expenditures of a lot of money that he just didn't have. He would need a job; so in late 1917 he returned to Winnipeg to work again at carpenter jobs. Then came an ankle fractured that would cause some delay in his farming efforts.
In 1918 their 2nd child, Winnie, was born (at Ericksdale, on the way back to Fairford). In 1919-20 Jim served as a School Trustee at Fairford with Alex MOAR and Thomas IRWIB (he was voted off).
In the 1921 Census at Fairford the family was recorded as follows: James SHAND, farmer, age 30 (born 1891 in USA; immigrated 1900); wife Rachel, age 31. Children: Raymond (age 5) and Winnie (age 3). The farm was located on Section 31-30-9-Wpm.
Rachel Dies at Fairford
Rachel died in May of 1922 at the young age of 37 (in childbirth), leaving Jim a widower with two very young children. What to do? Raymond was seven years old now. It was time to get him started in school. Winnie, a four year old motherless toddler, would need care and attention that Jim would certainly be unable to provide. His father had died; his mother (54 year old Widow Agnes) and his brother Walter (age 27) were far away in Keene, NH, USA. I don't know where his other two brothers were at this time (Tom & Joe), but as far as we know they were still single men then (ages 29 and 26). The closest person that Jim could turn to, who could be considered 'family', was deceased Rachel's adoptive sister, Agnes (nee KENNEDY) MAYO who was living in Selkirk at the time.
Agnes KENNEDY was born 1896, daughter of Juliet THOMAS (Rachel's sister) & John George KENNEDY. Something happened to her parents in 1906 that resulted in her being adopted by her grandparents, Mary Ann & William THOMAS (making her an adoptive sister to Rachel) at which time her name changed to Agnes THOMAS (by adoption).
Raymond and Winnie were taken to Selkirk where Rachel's adoptive sister, Agnes (nee KENNEDY-THOMAS) MAYO agreed to care for them.
Jim marries Eleanor MAYO
In Selkirk Jim SHAND soon became attached to Wallace MAYO's 24 yr old sister Eleanor, daughter of Caroline SUTHERLAND & Charles Edwin MAYO (1834-1917). ** MORE ABOUT CHARLES EDWIN MAYO
In July of 1923 they were married. Their first child, Caroline, was born in 1924. It seems that for the next couple of years Jim and his second family were living part of the time in Fairford where he was attempting to develop his farm, and part of the time in Selkirk and Winnipeg where he did carpentry work. Winnie and Raymond remained with the MAYO family in Selkirk so they could begin their schooling. We know that Raymond began his schooling in there in 1925. Son George was born in 1926.
The Selkirk School records indicated that Raymond was in Grade 2 (age 10) during the school year 1926-27. Winnie began school there in 1927 at the age of nine. She is also recorded there during the school term of 1828-29, but not Raymond.
In 1928 a third child (James SHAND Jr.) was added to Jim's second family. It was probably that year that Raymond was placed in the Fort Alexander Residential School in the Fort Alexander Indian Reserve. Jim was unable to complete his homesteading commitments at Fairford, so the homestead was cancelled in November that year.
Jim & Eleanor Move to Point du Bois
It has been said that Jim was living on Boyle Street (near the Louise Bridge) in Winnipeg when he applied for a parcel of land at Point du Bois, MB. In 1930 he moved there, without Winnie who was presumably left in Selkirk with the MAYO family.
In February of 1933 Winnie would have been yet 14 years old when she had an illicit affair in Selkirk with a 17 year old classmate/ neighbour named Howard OIG. On Oct 27, 1933 she gave birth to a baby daughter (Yvonne); about 3 months after her 15th birthday. It is not surprising that Yvonne soon became a ward of the Children's Aid Society in Winnipeg. Obviously no grandparents rushed forward to rescue her. Soon after, she became a foster child of Mary Ann (nee FIDLER) & Frank REID (1879-1936) in Mapleton. Later still, she became a foster child of Florence GRAY & Roderick SPENCE (1886-1960). There are many chapters in the life of this little orphan girl, beginning with the man who fathered her. She wouldn't even know who he was until she was in her late 60's. ** MORE ABOUT RODERICK SPENCE
Jim SHAND died July 11, 1956 at Point du Bois. Eleanor died in 1965.
To join in the discussions about this family, please do so at the following Link:
** DUSCUSSIONS ABOUT THE FAMILY OF JIM SHAND
============================ Family Details ================================
Children of Jim & Rachel THOMAS:
1. Aug 15, 1915 RAYMOND SHAND (m. Private/ Living)
2. July 30, 1918 WINNIFRED GERTRUDE SHAND (m1. Howard OIG, m2. George SOULSBY, m3. Russell TAYLOR)
** MORE ABOUT WINNIE SHAND
Children of Jim and Eleanor MAYO:
Six children - Private