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Home | | Modern Pharmacology with Clinical Applications | Biomedical Ethics and Clinical Research
Chapter: Modern Pharmacology with Clinical Applications: Contemporary Bioethical Issues in Pharmacology and Pharmaceutical Research
Author : Charles R. Craig, Robert E. Stitzel Posted On : 22.12.2017 06:41 pm
Biomedical Ethics and Clinical Research
For more than 50 years, scientists, physicians, bioethi-cists, and the media have focused on a variety of issues in research with human subjects, or clinical research.
For more than 50 years, scientists, physicians, bioethi-cists, and the media have focused on a variety of issues in research with human subjects, or clinical research. In 1948, in response to the atrocities perpetrated by Nazi experimentation, the Nuremberg Code was developed to set forth guidelines for the acceptable conduct of sci-entific research. In 1964 the World Medical Association adopted the Declaration of Helsinki, which specifically guides physicians in biomedical research. These docu-ments specify basic moral guidelines ultimately founded on concerns for autonomy, beneficence, and justice. The guidelines require the following:
· Subjects must give voluntary consent before being enrolled in any study after being fully ad-vised of the study's aims, methods, benefits, risks, and discomforts.
· Proposed studies must have sufficient scientific merit to warrant their risks.
· Studies must be designed to avoid all unneces-sary physical and mental suffering.
· Potential benefits to subjects must outweigh risks to subjects.
· Researchers must ensure subjects' privacy and confidentiality.
· Subjects must have the right to withdraw from the study at any time.
· Researchers are obligated to stop the study if continuation is likely to result in injury to sub-jects.
The guidelines further require that research on hu-man subjects be conducted by qualified individuals and that most clinical research be reviewed by an independ-ent committee, which is generally an institutional re-view board.
In addition to the Nuremberg Code and Declaration of Helsinki, The International Ethical Guidelines for Biomedical Research Involving Human Subjects was issued in 1982 and revised in 1993 by the Council for the International Organization of Medical Sciences (CIOMS). Those guidelines define national policies for biomedical research, apply ethical standards to the cir-cumstances often present in research in economically developing nations, and define mechanisms for ethical review of human subjects research.
In drug studies, specific ethical concerns focus on balancing benefits and burdens to subjects, on the need for investigators to use noninvasive and minimally painful means of determining drug disposition, on min-imizing the frequency of bodily fluid sampling, and on choosing study subjects who are representative of the target population whenever possible rather than expos-ing healthy volunteer subjects. Placebo-controlled stud-ies create special obligations pertaining to the potential deception of subjects and raise difficult questions about subjects' informed consent.
Recently, attention has focused on the issue of in-ternational medical research, especially that done with patients in economically developing nations. For ex-ample, one controversy focused on a highly publicized placebo-controlled study in Africa examining the pre-vention of perinatal transmission of HIV using azi-dothymidine (AZT). Since such a study in an econom-ically developed nation would probably not have a placebo arm, critics argue that this reflects a double standard for research. They assert that one standard for ethical research should prevail, regardless of the social and economic conditions of the subjects. Bioethicists and those directly involved in research are reconsidering whether subjects who are already suf-fering under impoverished conditions might suffer fur-ther exploitation at the hands of medical researchers.
Those who designed the study point out that placebo-controlled studies are the most rigorous avail-able and that AZT would not otherwise be available to this population. Enrollment in the study offered a ben-efit over and above the status quo, they assert, and did not deprive subjects of anything they could otherwise obtain. Yet such "studies in nature" pose complex ethi-cal issues. If the research relies on the continuation of undesirable social conditions, such as the general lack of prenatal care, critics assert that there is a fundamental obligation to improve those background conditions rather than take advantage of access to the perfect "laboratory." While the clinical study has certainly not made the underlying conditions worse, the study has done little to correct the underlying deprivations. Even so, is that the role of pharmaceutical research or a broader social role that goes beyond what researchers should have to provide? While it would be foolhardy to insist that the only ethically acceptable research is done on patients with full access to comprehensive health care, we do not want to make those who are already de-prived and in poverty into "lab rats" who participate in research that ultimately benefits primarily those in the developed world.
Clinical research can target the needs of those in economically developing nations and those who are medically underserved in the United States. Yet we must be cautious in the design and implementation of research studies to ensure that those who are the most vulnerable, whether locally or abroad, are offered the most protections and stand to gain proportionately from the studies in which they participate. Research must satisfy the needs of the population in which it is undertaken, and the products developed during the course of the research must subsequently be made rea-sonably available.
Manifestations of Toxicity
Treatment of Poisonings
Exposure to Nontherapeutic Toxicants
Applications of Toxicological Principles
Biomedical Ethics in Pharmacology: An Introduction and Framework
Conflicts of Interest and the Pharmaceutical Industry
General Organization and Functions of the Nervous System
Anatomic Differences Between the Somatic and Autonomic Nervous Systems
Autonomic Nervous System
Autonomic Neurotransmitters
Innervation of Various Organs by the Sympathetic and Parasympathetic Nervous Systems
The Adrenal Medulla


The Mall of America had been open only 17 minutes Friday morning when the screaming started.
On the first floor, laying face up between an escalator and the Michael Kors store, was a 5-year-old boy. He had been thrown from three stories above - by a stranger, police say. There was blood; the boy was not moving.
"That's a pretty high fall,"
Police: Child pushed from 3rd floor of Mall of America, 24-year-old suspect in custody.
Bloomington Police are giving an update about the Mall of America attack.
Investigators say Emmanuel Aranda, who has violent roots in Chicago, tossed a 5-year-old stranger off a third story balcony at Minnesota\'s Mall of America.


text:
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// flow-typed version: <<STUB>>/json2md_v^1.5.2/flow_v0.33.0

/**
 * This is an autogenerated libdef stub for:
 *
 *   'json2md'
 *
 * Fill this stub out by replacing all the `any` types.
 *
 * Once filled out, we encourage you to share your work with the
 * community by sending a pull request to:
 * https://github.com/flowtype/flow-typed
 */

declare module 'json2md' {
  declare module.exports: any;
}

/**
 * We include stubs for each file inside this npm package in case you need to
 * require those files directly. Feel free to delete any files that aren't
 * needed.
 */
declare module 'json2md/dist/json2md.min' {
  declare module.exports: any;
}

declare module 'json2md/lib/converters' {
  declare module.exports: any;
}

declare module 'json2md/lib/index' {
  declare module.exports: any;
}

// Filename aliases
declare module 'json2md/dist/json2md.min.js' {
  declare module.exports: $Exports<'json2md/dist/json2md.min'>;
}
declare module 'json2md/lib/converters.js' {
  declare module.exports: $Exports<'json2md/lib/converters'>;
}
declare module 'json2md/lib/index.js' {
  declare module.exports: $Exports<'json2md/lib/index'>;
}

redpajama_set_name: RedPajamaGithub


Hestermeyer, H. P., 2016, In : JOURNAL OF INTERNATIONAL ARBITRATION.
Hestermeyer, H. P., 2007, Hardback ed. Oxford University Press. 369 p.
Wolfrum, R. (ed.), Stoll, P-T. (ed.) & Hestermeyer, H. P. (ed.), 2011, Martinus Nijhoff Publishers. 1265 p.


text:
Q: Replace with partial match I have some issues with expressions like the following
A^3B^4/b + A^3B^4C/d

in that I want to substitute A^3B^4 and A^3 B^4C with γ andδ, respectively. However, if I am going to use ReplaceAll, then I need to take care of the order, i.e.,
/.{A^3B^4C -> δ, A^3B^4 -> γ}

gives the right output, whereas
/. {A^3B^4 -> γ, A^3B^4C -> δ}

does not. I have tried to use Replace, but to use it I need to specify the coefficients attached to each term in the expression. Regrettably this is not feasible as the expressions I need to handle are way more complex and lengthy that the one above. Any ideas?

I'll give you a simple example. With
A^2*B^4*C + A^2*B^4 /. {A^2*B^4*C -> gamma, A^2*B^4 -> delta}

I get

gamma + delta

the answer I want. But with
A^2*B^4*C + A^2*B^4 /. {A^2*B^4 -> delta, A^2*B^4*C -> gamma}

I get

 delta + C delta

A: $Version

(* "11.3.0 for Mac OS X x86 (64-bit) (March 7, 2018)" *)

expr = A^3 B^4/b + A^3 B^4 C/d;

rules = {A^3 B^4 -> Γ, A^3 B^4 C -> Δ};

expr /. rules

(* Γ/b + (C Γ)/d *)

As you point out, reversing the rules works in this simple case
expr /. Reverse@rules

(* Γ/b + Δ/d *)

More generally, put the longer rules first
rules2 = SortBy[rules, -LeafCount[#[[1]]] &];

expr /. rules2

(* Γ/b + Δ/d *)

A: Using Simplify with your rules as constraints works for your example inputs:
Simplify[A^3 B^4/b + A^3 B^4 C/d, {A^3B^4C == δ, A^3B^4 == γ}]

γ/b + δ/d

Simplify[A^2 B^4 C + A^2 B^4, {A^2 B^4 C == γ, A^2 B^4 == δ}]

δ + γ

A: There is no general solution to this problem. It is similar to what Mathematica tries when sorting the DownValues of function and like Mathematica's internal algorithm, each automatic way of sorting your rules is bound to fail for sufficiently complex or degenerated cases.
For instance, you could in more complex situations have patterns inside your rules and since they can match nested expressions, the sorting by leaf-count might fail. Consider for instance this
A^2*B^4*C + A^2*B^4 /. {A^2*B^4 -> delta, A^2*_*C -> gamma}

The first part of the second rule is similar (although it matches more than B^4) to your example, but the leaf-count is smaller. I see two solutions
(1) Like in writing a lexer with flex, you need to take care of the correct rule ordering yourself. Btw, this is done in Rubi as well. Although the goal is somewhat different there, when the Rubi package is loaded, the integration rules are being loaded in a very specific order, because otherwise, it would not work. In your case, this means you have to sort your rules so that longer matches, that contain valid matches of other rules are tested first.
(2) You can use a different way of writing rules. Instead of
{A^2*B^4 -> delta, A^2*B^4*C -> gamma}

you use
{A^2*B^4 -> delta, delta*C -> gamma}

and use ReplaceRepeated. This gives your rules a strict one-way layout. No rule is allowed to contain a portion that is a match for another rule.

A: A custom ordering function to sort rules:
order[a_Rule, b_Rule] := (a /. b) =!= a;

expr = A^3 B^4/b + A^3 B^4 C X/d;
rules = {A^3 B^4 -> Γ, X -> ρ, A^3 B^4 C -> Δ}

{A^3 B^4 -> Γ, X -> ρ, A^3 B^4 C -> Δ}

Sort[rules, order]

{A^3 B^4 C -> Δ, X -> ρ, A^3 B^4 -> Γ}

Using ReplaceAll with original or sorted rules does not give the desired result:
expr /. rules

Γ/b + (C X Γ)/d

expr /. Sort[rules, order]

Γ/b + (X Δ)/d

We get the desired result by Folding  ReplaceAll over the sorted rules:
Fold[ReplaceAll, expr, Sort[rules, order]]

Γ/b + (Δ ρ)/d

or using ReplaceRepeated with the sorted rules:
expr //. Sort[rules, order]

Γ/b + (Δ ρ)/d

Carl's approach is the cleanest as it does not require any additional processing:
Simplify[expr, rules /. Rule -> Equal]

Γ/b + (Δ ρ)/d

redpajama_set_name: RedPajamaStackExchange


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The cookies that we use on our website are used to differentiate our valued customers from one another so that we can provide you with a unique and customized experience while shopping on our website.
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American Medical Products may use a third party to help us operate our business in a much more efficient manner – either by sending out our business newsletters or by processing credit card payments that we receive. Our Customers can rest assured that their personal data will only be used for the efficient operation of our business as it pertains to you.
If, at any point, you are interested in viewing the data that American Medical Products has on file for you, whether to correct or modify information or to simply see what we have, please contact one of our outstanding customer care professionals. Our customer care staff will be happy to provide you with the information that you are looking for.
American Medical Products would like our customers to note that we cannot be held responsible for the privacy practices of the websites that offer a link to or a link from our website. American Medical Products may occasionally recommend a business or product from our own website, we cannot be held responsible for their own privacy and business practices. We urge our Customers to be informed consumers and make a note of the rules and privacy policies that other websites maintain.
· American Medical Products pledges never to sell the information provided by our customers to a third party – under any circumstances.
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text:
Q: Blazor/Razor Components do something when bound value changes I have been researching this but finding a dozen answers that don't seem quite right. What I'm trying to do seems like a common use case with a simple answer that I'm not finding.
I have, below, a .razor file with a small form, with a Start DateTime and a Duration. I want to update the EndDate property when either of these change--primarily I was starting with the Duration <select> when I got stuck. (Ignore the Telerik stuff for now, except to understand that it gives me a DateTime value in the bound startDate property).
Using @bind in the <select> precludes using @onchange on the same element... so, okay, I probably want something that responds to the change of the property values anyway... Well, INotifyPropertyChanged is used for that, and I started down that road, but it seems out of place with this pre-existing data binding mechanism. I found documentation on EventCallback, but that seems designed for inter-component communication, not within a component and I would be shoehorning it in. I could define the setters on the properties, but that also seems old fashioned in context...
In Ember, I would have used dependent properties for this.  Am I missing the intended way to do this in Blazor? Is INotifyPropertyChanged the correct way to go here?
@page "/"

@using System.ComponentModel
@using System.Runtime.CompilerServices
@using Envoi.BlazorApp.Annotations
@using Telerik.Blazor.Components

Record Encounter

<TelerikDateTimePicker Min="@Min" Max="@Max" @bind-Value="@startDate"
                       Format="ddMMM yyyy HH:mm:ss" Width="220px"></TelerikDateTimePicker>
Duration:
<select @bind="Duration">
    <option value="5">5 Minutes</option>
    <option value="15">15 Minutes</option>
    <option value="30">30 Minutes</option>
    <option value="60">1 Hour</option>
    <option value="120">2 Hours</option>
</select>

End: @(endDate.ToShortDateString()) @(endDate.ToShortTimeString())
(@(startDate.ToShortDateString()) @(startDate.ToShortTimeString()) + @Duration minutes)

@code
{

    private DateTime startDate = DateTime.Now;
    public DateTime Min = new DateTime(2006, 10, 1, 0, 0, 0);
    public DateTime Max = new DateTime(DateTime.Now.Ticks + TimeSpan.FromDays(365.25*4).Ticks);
    public int Duration { get; set; } = 5;
    public DateTime endDate;

    private void UpdateEndDate() // How to get this method called?
    {
        endDate = new DateTime(startDate.Ticks + TimeSpan.FromMinutes(Duration).Ticks);
    }

}

A: Okay this seems to be an instance of not seeing the forest for the trees. Basically, I just needed to go with this set of property definitions instead:
private DateTime StartDate { get; set; } = DateTime.Now;
public DateTime Min = new DateTime(2006, 10, 1, 0, 0, 0);
public DateTime Max = new DateTime(DateTime.Now.Ticks + TimeSpan.FromDays(365.25 * 4).Ticks);
public int Duration { get; set; } = 5;
public DateTime EndDate => new DateTime(StartDate.Ticks + TimeSpan.FromMinutes(Duration).Ticks);

So, there were I think two problems:

*

*StartDate (nee startDate) was not actually compiling as a property... so I imagine Blazor was probably not catching changes properly.

*I just needed to have a lambda-based property for endDate that computed the value... because of course I did. [Not like I could have that as a settable property and a computed property at the same time, right? If I want another way to override and set the end date as well, I'll have to have a separate EndDate (settable) and ComputedEndDate (lambda) that checks EndDate... which is perfectly reasonable.]*

Edit
* And after writing this I later remembered... Actually yes, that's exactly what I wanted: like the many right-triangle solvers and subnet calculators out there, I was originally imagining an interface where you could set any of the three values (StartDate, Duration or EndDate) and one of the other properties would update to match... and you can't really do that with this approach because each property is either writable and not updating, or updating and read-only.
It does not appear that Blazor has a baked-in way to do this. This article discusses a few ways to do it, mainly variations on the options I already proposed. So while my answer addresses the specific problem I got stuck on with one-way properties, the larger problem does not appear to have a quick and easy solution.


text:
Village Blog
Military Academy
Tag: Military Academy
Africa Nigeria West Africa World
Nigeria: Two dead as gunmen attack military academy
August 25, 2021 Elwin Mandowaafrica, africafeeds, Gunmen, Military Academy, News, Nigeria, west africa
– – At least two people have been killed after gunmen attacked a top military academy in Nigeria. Local media reports say another person has been abducted at the Nigerian Defence Academy which trains elite officers from Nigeria and other African countries. An army spokesman said the assailants broke into the campus in the northern city of Kaduna in the early hours of Tuesday morning. In a statement the academy said "The security architecture of the Nigerian Defence Academy was compromised" on Tuesday "by unknown gunmen, who gained access into the…

redpajama_set_name: RedPajamaCommonCrawl


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text:
TO:CMA Spherical Generator
Angel Francisco Martinez
Laredo , United States
A team of Cornell engineers developed a patented technology, the TO:CMA Spherical Generator, that creates copious amounts of clean electricity out of ocean waves at costs below all major existing renewable energy sources. The design was elaborated to defy the global rise in energy demand, which is projected to grow by 49% over the next 30 years and the depletion of current resources that are used for energy.
This device surpasses in potential and efficiency existing renewable energy technology, and is more economical. The innovative geometrical arrangement of the magnets within the technology generates more power and greater efficiency at less cost.
Conventional point absorbers employ linear generators, which can only harness energy from movement in the vertical motion. The limited one-degree of freedom of motion of the magnets in the linear generators drastically reduces the ability to harness energy from the waves since buoys experience motion in all six degrees of freedom when deployed offshore. Our design can break off this constraint and harness power from movement in all six degrees freedoms through its unique configuration of the novel permanent magnet generator.
Our invention will supplement the electricity produced from wind farms by harvesting the vast energy of the waves in between the wind towers. Since the major costs of building offshore power generating plants will have already been invested in laying the expensive ocean bottom power lines, the buoys will have very low average costs for these offshore wind plants.
As of 2011, there are 50 European off shore wind farms that could support at least 500 buoys each. This particular market is expected to grow to 100 wind parks worldwide by 2016.
The design is based on the geometrical rearrangement of the Linear Inductance Permanent Magnet Generator (LIPMG). Three rings on concentric sizes and perpendicular arrangement are to be housed in a waterproof buoy that will transfer the force of the passing waves into motion of magnets. Electrical current is produced as a result of the motion between the wire loop and the magnets in accordance with Faradays Law. For synergy reasons, arrays of these buoys will be installed in between wind turbines of offshore wind farms.
Manufacturing will be given to a qualified contractor in India, China or Mexico. Installation and maintenance of the devices in the offshore wind farms in Europe will go to European contractors. Both measures reduce the time to market and guarantee quick scalability.
Since the major costs of building offshore power generating plants will have already been invested in laying the expensive ocean bottom cables, our buoys will have very low average costs for these wind farms. In comparison to similar products, the TO:CMA Spherical Generator has the main advantage of being cheaper to produce, and easier to handle (due to its smaller size), while being very close to the competition in its effectiveness.
2011 Sustainable Technology Category Winner
2011 Top 10 Most Popular
Delia Beatriz Martinez
Trupti Bulbule
Angel Francisco's favorite design and analysis tools:
Solid Works and COMSOL
For managing CAD data Angel Francisco's company uses:
Angel Francisco's hobbies and activities:
Ice hockey and meditation
Angel Francisco belongs to these online communities:
TOCMA.net
Angel Francisco is inspired by:
Contributing to the re-structuring of the systems that pertain to sustainable development and all of the technology that has impacted qualitatively the lives of the common and the numerous ecosystems of earth.
I am inspired by the works of visionaries like Nikola Tesla and Howard Hughes.
Solidworks, COMSOL


text:
from rest_framework import serializers

from onadata.apps.logger.models import Note

class NoteSerializer(serializers.ModelSerializer):
    class Meta:
        model = Note


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text:
Published On: Sun, Oct 19th, 2014
Television | By Stephen Nevets
Brandon Routh talks 'Arrow' season 3 role, 'The Flash' tie-in and uniform
While the Arrow is back and The Flash is just beginning, fans may be pleased to learn more about another hero in the mix, The Atom. Superman Returns star Brandon Routh plays Ray Palmer and appears on the Arrow as part of a hostile takeover of Queen Industries.
Talking with MTV, Routh discussed some sort of a flashback episode that Arrow executive producers Marc Guggenheim and Andrew Kreisberg were thinking about when the actor joined the series. The episode could focus entirely on Ray Palmer or "just about the day that something happened in his life at the same time that it happened in other characters' lives."
"Marc said that if the shrinking was going to happen, it's more likely to be on The Flash. But I have no knowledge of a crossover or any of that. Arrow is very grounded in reality, so nobody really has any powers. That is a challenging thing, to have you bring a character like the Atom in, with his trademark thing being that he shrinks…"
The current storyline has Palmer "chasing" after Felicity.
"I continue to pursue Felicity to hire her," Routh told MTV News. "She's the best tech brain in the city, or maybe even further than that. I definitely had my eyes on her from the beginning — coming to Tech Village for the first time, not necessarily knowing anything about what she looks like. [It was] just about her brain and her abilities and skills. I continue to do that, but once I see her and meet her, maybe it becomes a dual purpose. But at the forefront I need her skills for my plans, as I continue to try to make them happen. And Ray Palmer tends to get what he wants."
Fans need to know there is certainly more planned for Palmer in the CW universe."
"They have a plan [for Ray's powers], I just don't know all of it because I am a silly actor and I tend to run my mouth just like other silly actors, so they don't tell us everything," he said. "But just because he's not shrinking doesn't mean that he might not be doing something else, or be involved in some other kind of superhero-y way. I know that there is some type of suit thing happening, though I'm not at liberty to discuss much. But it looks cool, and I would be happy to wear it."
Check out the full details from Routh HERE
Arrow Season 3 airs Wednesdays at 8pm ET on CW.
Stephen Nevets - Stephen is a contributor and writer on The Dispatch. Stephen is the founder and editor for the Steven Spielberg Fan Club website and contributes to pop culture stories on The Dispatch, especially upcoming movie news. Beginning in 2016, Stephen took the role of Managing Editor for the Tampa Dispatch.
ArrowArrow 3 plansArrow season 3Brandon RouthCW networkGreen ArrowGreen Arrow TV seriesMarc Guggenheimsuperhero TV showSuperman ReturnsThe FlashTV seriesTV show
How to See Your Shows During Long Journeys Abroad
Legends of Tomorrow season 5 arrives on Blu-Ray, digital in September
The Flash season 6 Blu-ray, digital release and details emerge
Syfy details the MastersFX transformation of 'The Magicians'
Vinnie Jones joins 'Arrow' season 3 as a villain named Brick - The Global Dispatch says:
[…] CW show has added Brandon Routh as Ray Palmer/Atom and J.R. Ramirez as Ted Grant/Wildcat, so the franchise continues to grow. There is also […]


In this step you create a web server to connect to the Amazon RDS DB instance that you created in Step 1: Create an RDS DB Instance.
First you create an Amazon EC2 instance in the public subnet of your VPC.
Choose EC2 Dashboard, and then choose Launch Instance, as shown following.
Choose the Amazon Linux Amazon Machine Image (AMI), as shown following.
Choose the t2.small instance type, as shown following, and then choose Next: Configure Instance Details.
Network: Choose the VPC with both public and private subnets that you chose for the DB instance, such as the tutorial-vpc (vpc-identifier) created in Create a VPC with Private and Public Subnets.
Subnet: Choose an existing public subnet, such as subnet-identifier | Tutorial public | us-west-2a created in Create a VPC Security Group for a Public Web Server.
Auto-assign Public IP: Choose Enable.
On the Add Storage page, keep the default values and choose Next: Add Tags.
On the Add Tags page, shown following, choose Add Tag, then enter Name for Key and enter tutorial-web-server for Value.
Choose Next: Configure Security Group.
On the Configure Security Group page, shown following, choose Select an existing security group, and then choose an existing security group, such as the tutorial-securitygroup created in Create a VPC Security Group for a Public Web Server. The security group must include inbound rules for SSH and HTTP access.
On the Review Instance Launch page, shown following, verify your settings and then choose Launch.
On the Select an existing key pair or create a new key pair page, shown following, choose Create a new key pair and set Key pair name to tutorial-key-pair. Choose Download Key Pair, and then save the key pair file on your local machine. You use this key pair file to connect to your EC2 instance.
To launch your EC2 instance, choose Launch Instances. On the Launch Status page, shown following, note the identifier for your new EC2 instance, for example: i-0288d65fd4470b6a9.
To find your instance, choose View Instances.
Wait until Instance Status for your instance reads as running before continuing.
Next you connect to your EC2 instance and install the web server.
To connect to the EC2 instance that you created earlier, follow the steps in Connect to Your Instance.
The -y option installs the updates without asking for confirmation. To examine updates before installing, omit this option.
After the updates complete, install the Apache web server with the PHP software package using the yum install command, which installs multiple software packages and related dependencies at the same time.
For more information, see Updating Instance Software.
Start the web server with the command shown following.
You can test that your web server is properly installed and started by entering the public DNS name of your EC2 instance in the address bar of a web browser, for example: http://ec2-42-8-168-21.us-west-1.compute.amazonaws.com. If your web server is running, then you see the Apache test page. If you don't see the Apache test page, then verify that your inbound rules for the VPC security group that you created in Tutorial: Create an Amazon VPC for Use with an Amazon RDS DB Instance include a rule allowing HTTP (port 80) access for the IP address you use to connect to the web server.
The Apache test page appears only when there is no content in the document root directory, /var/www/html. After you add content to the document root directory, your content appears at the public DNS address of your EC2 instance instead of the Apache test page.
Configure the web server to start with each system boot using the chkconfig command.
To allow ec2-user to manage files in the default root directory for your Apache web server, you need to modify the ownership and permissions of the /var/www directory. In this tutorial, you add a group named www to your EC2 instance, and then you give that group ownership of the /var/www directory and add write permissions for the group. Any members of that group can then add, delete, and modify files for the web server.
Add the www group to your EC2 instance with the following command.
Add the ec2-user user to the www group.
To refresh your permissions and include the new www group, log out.
Log back in again and verify that the www group exists with the groups command.
Change the group ownership of the /var/www directory and its contents to the www group.
Change the directory permissions of /var/www and its subdirectories to add group write permissions and set the group ID on subdirectories created in the future.
Recursively change the permissions for files in the /var/www directory and its subdirectories to add group write permissions.
Next, you add content to your Apache web server that connects to your Amazon RDS DB instance.
While still connected to your EC2 instance, change the directory to /var/www and create a new subdirectory named inc.
Create a new file in the inc directory named dbinfo.inc, and then edit the file by calling nano (or the editor of your choice).
Add the following contents to the dbinfo.inc file, where endpoint is the endpoint of your RDS MySQL DB instance, without the port, and master password is the master password for your RDS MySQL DB instance.
Placing the user name and password information in a folder that is not part of the document root for your web server reduces the possibility of your security information being exposed.
Save and close the dbinfo.inc file.
Change the directory to /var/www/html.
Create a new file in the html directory named SamplePage.php, and then edit the file by calling nano (or the editor of your choice).
Save and close the SamplePage.php file.
Verify that your web server successfully connects to your RDS MySQL DB instance by opening a web browser and browsing to http://EC2 instance endpoint/SamplePage.php, for example: http://ec2-55-122-41-31.us-west-2.compute.amazonaws.com/SamplePage.php.
You can use SamplePage.php to add data to your RDS MySQL DB instance. The data that you add is then displayed on the page.


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Feds: Rep. Duncan Hunter used campaign cash for affairs
June 25, 2019 at 5:28 PM EDT - Updated June 25 at 7:51 PM
By MICHAEL R. BLOOD Associated Press
LOS ANGELES (AP) — U.S. Rep. Duncan Hunter of California illegally used campaign money to finance romantic flings with lobbyists and congressional aides, spending thousands of dollars on meals, cocktails and vacations, federal prosecutors say.
A government court filing late Monday detailed allegations about the married Republican congressman's affairs with five women following an indictment last year charging Hunter and his wife with misspending more than $200,000 in campaign funds on trips and other personal expenses.
Margaret Hunter, who served as the congressman's campaign chairwoman, pleaded guilty this month to one count of corruption and agreed to testify against her husband.
In the new motion, prosecutors reconstructed Rep. Hunter's alleged clandestine lifestyle with precision, providing times when he arrived and departed after liaisons and listing a wide range of expenses he represented as campaign-related activity, such as paying for dates with a woman who had become his lover shortly after she started working in his office.
He used his campaign treasury for even seemingly incidental purchases — a $7 beer at a hotel bar while on a ski trip with one of the women, and an Uber ride after a liaison with another lobbyist in October 2015.
Hunter has said he is the target of politically motivated prosecutors. His lawyer, Gregory Vega, didn't immediately respond to a message seeking comment about the new court filing.
It came the same day Hunter's attorney filed a motion to dismiss the indictment, arguing that the search and seizure of his congressional records violated the Constitution.
Vega wrote that the Constitution does not place members of Congress above the law but does "protect them from prosecution for their legislative activities and from having to disclose legislative records, absent their consent."
In an interview with Fox News last year, the six-term congressman said his campaign made mistakes, that he gave his wife power of attorney when he deployed as a Marine to Iraq in 2003 and that she handled his finances during his last five terms in office.
The government's filing suggested that Hunter tapped into campaign funds because he had no other source of money to bankroll his romantic relationships. During a weekend ski trip with a lobbyist, his personal bank account had a negative balance and he had been hit with $33 fees six times for overdrawing the account, prosecutors said.
"Given the pronounced financial difficulties the Hunters were facing, his use of campaign funds to pursue these relationships was necessary for Hunter to satisfy his desire for intimacy," prosecutors wrote.
The filing provided a look into a string of his alleged relationships and an accounting of campaign funds that were spent. Among them:
— Sometime after April 2009, shortly after coming to Congress, Hunter became romantically involved with a lobbyist and began staying at her home while occasionally spending campaign funds for food and beverages, prosecutors said.
— In January 2010, Hunter flew to Reno, Nevada, ostensibly to attend a convention for a nonprofit group. After a brief stop at the convention, Hunter and a lobbyist headed for a ski resort near Lake Tahoe, where they spent the weekend skiing and ordering room service, according to the filing. Prosecutors said Hunter used campaign funds to rent a car, pay the hotel tab and fly back to Washington.
— In August 2012, while attending the Republican National Convention in Tampa, Florida, Hunter began a romantic relationship with a woman who worked for a member of the House leadership. Hunter later began staying at her home "nearly every night," prosecutors said. He used campaign funds for cocktails and Uber rides.
— On Sept. 14, 2016, Hunter and another lobbyist engaged in "intimate personal activities unrelated to Hunter's campaign," prosecutors said. He used campaign funds to pay for an Uber to return to his office the next morning.
Prosecutors said evidence about the congressman's affairs is necessary to "demonstrate Hunter's ... intent to break the law and to establish his motive to embezzle from his campaign."
Alluding to the motion to dismiss the charges, prosecutors wrote that the "sequence of romantic liaisons is so far removed from any legitimate campaign or congressional activity as to rebut any argument that Hunter believed these were proper uses of campaign funds."
The government's filing also referred to "additional potentially sensitive conduct" by the congressman with personal friends that could taint the jury pool if revealed. Both sides are discussing an agreement in which evidence of the get-togethers, financed by campaign dollars, would not be introduced at trial.
Hunter was re-elected by Southern California's most Republican congressional district last year despite the indictment. His trial is set for Sept. 10.
His lawyer also filed a motion to move the court case out of San Diego County, predicting that Hunter would not receive a fair trial because of "enormous negative local media coverage."
He also said Hunter's ties to President Donald Trump could taint the trial with politics, because Trump lost the county in the 2016 election by 18 points. He said Hunter could get an impartial jury in the court's Eastern District of California, which includes several largely rural counties carried by Trump in 2016.


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It means our attention span and consequently our tolerance of unpopular governments is much shorter than it was in the past.
Instead of giving leaders and governments a second chance, or at least enough time to see if their promised reforms are being delivered, we seem to want to punish them at the ballot box while the jury is still out about the efficacy of their plans and strategies. In doing so, we stifle the capacity for long-term reform and planning.
What is the incentive for governments to pursue reforms that will pay off in a decade when all we are concerned about are our individual circumstances and our material and emotional wellbeing in the next minute or hour or two?
The disappointing reality is, if we punish forward-thinking governments, then there is no incentive for politicians to be forward thinking in the first place.
In the not-so-recent past, great reforms took years — and, in some cases, successive governments — to implement.
Consider this. On January 18, 1979, John Howard as treasurer in the Fraser government appointed the Campbell inquiry into our financial system.
The explicit goal of the inquiry, according to Howard, was to kick-start reform so the financial system could "meet the current and future needs of the Australian economy.
It was more than two years later, in 1981, that the committee delivered its 800-plus page report to the government. It took a further two years — including a change of government — for one of the key recommendations of the report, the floating of the dollar, to be implemented in December 1983. By 1986, many of the key reforms of the Campbell inquiry had been adopted by the Hawke Labor government.
All of this makes me question if Australians would have the same appetite and patience for reform if reforms of that scale were proposed today.
We already know the answer to this — and the first-term Abbott government has learned the hard way. Joe Hockey's 2014 budget tried to solve decades' worth of future problems in a single bound and that included reform of the fiscal situation, a rethink of the relationship between the individual and the government, and ambitious policies to "future proof Australia.
But while some citizens might have respected its noble aims, Hockey's first budget was far too ambitious for most electors.
Voters weren't thinking about what the policies would mean in 10 years, they were thinking about how the policies would affect them in a year or maybe less.
If the opinion polls at the time were anything to go by, if the Treasurer and Tony Abbott had stuck to key elements of their plan voters would have been more than prepared to give the federal government a huge kick at the ballot box. In state politics, a similar situation is occurring, with first-term governments thrown out in Queensland and Victoria.
In Queensland, it wasn't just that voters weren't thinking long term about the future, it was that they also had forgotten the past.
The first-term Newman government was thrown out for Labor, which had been slaughtered at the previous state election.
Voters seemed to forget the anger that led them to boot out Campbell Newman and his Liberal National Party team this year was the same anger used dramatically to eject Anna Bligh a few years earlier.
They also forgot that, despite Queensland Labor's strong anti-privatisation campaign this year, it was Bligh who remarked in 2009 with reference to electricity privatisation that "in a household if you want a new car, then you sell your old car.
Admittedly, Newman squandered the public's goodwill and was personally responsible for not being able to see through his own reforms.
Last Saturday in NSW, a neophyte opposition leader — standing against a popular, cleanskin premier — achieved a swing to Labor of 9 per cent which, not so long ago, would have been a game changer.
All of this febrile electoral energy calls for a rethink of our political system. But instead of it being led from the top to the bottom, this fundamental change needs to be initiated by the voters, not by our political leaders.
As citizens, we ought step back and think that the same instant gratification we have come to expect in most parts of our lives simply cannot and should not determine our voting intentions. To allow this short-sightedness to influence our choices at the ballot box simply will lead to a revolving door of state and federal governments with nothing significant actually being achieved before the next mob briefly occupies the ministerial offices. Starting now, we ought to try to stop this absurd electoral merry-go-round.
Maybe, just maybe, the next time we vote, we should think more clearly about Australia's future before we take our short memories and even shorter memory spans back to the ballot box.
Ross Fitzgerald is the author of 36 books, including his memoir, 'My Name is Ross: An Alcoholic's Journey', available as an e-book and as a talking book from Vision Australia.
The Weekend Australian, April 4-5, 2015, Inquirer p 20.
Ross Fitzgerald ("Let's vote with an eye to the future and stop this electoral merry-go-round", 4-5/4) calls for voters to take a long-term view but, as ongoing global financial crisis shows, it is far from clear whether we should hang on to our old Australian-made cars, or replace them with a new imported model, or use public transport more and just hire a car when needed.
The Australian, April 6, 2015, p 11.


Paranormal Games | Paranormal U.S.
Have You Played Any of These?
Things have grown considerably in the world of paranormal related games since I was a kid. I am not referring to the hundred of video games we all have access to. I am talking about the personal games we can play alone, with relatives or friends in person…all hands on. These games are all paranormal related and are those that are not routinely heard of. Many are for teens, young adults or for the kid in you. We've all heard of Candy Man, the Ouija Board and Mary. These are the not so popular ones. If you know about a scary paranormal related game, please leave me the information in the comments section at the end of this article. Thanks.
The detailed instructions can be found here if you are interested in playing any of these games. I've reviewed several of them and for the most part, they appear to be best suited for teens and young adults.
Here is an interesting adult interaction game called Hidden Spirit Game (posted for Halloween) but one that can be played at any time. For more interactive paranormal games you can test your skills here.
Games were crucial social and cultural bonding events and also important teaching tools and indicators of social status in many cultures around the world. Games were given as gifts and were common in the court culture with royalty. Historic games such as the Mesoamerican Ball Game and Senet were full of religious and mythic significance. Games such as The Mansion of Happiness and Gyan Chauper taught ethical and spiritual lessons. Weigi and Shatranje were games that developed mental skills and strategic thinking used by the military and those involved in politics.
There is currently a top listing of the best horror games for PS4, Xbox, One, PS3, Xbox 360 and PC. One that I have checked out is called Sanitarium. Sanitarium is a point and click psychological horror games that was released for Microsoft Windows and published by ASC games.


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Gavin v. Loane [1821] NSWKR 12; [1821] NSWSupC 12
Charter of Justice - Van Diemen's Land - Lieutenant Governor's Court, jurisdiction - Supreme Court, jurisdiction
Field J., 4 September 1821
Source: Sydney Gazette, 8 September 1821[1]
This day Mr. Justice Field pronounced the following judgement touching our Charter of Justice:
"In this action, which was tried at Van Diemen's Land, the defendant pleaded the jurisdiction of the Lieutenant Governor's Court in bar; to which plea the plaintiff, instead of denying that the cause of action was under £50, demurred generally. The Court gave judgement for the defendant upon the demurrer; for it is clear that the Governor's and Lieutenant Governor's Courts being exclusive jurisdictions may be pleaded in bar, and if the plaintiff meant to rely on my printed opinion, that such a plea under our Charter of Justice should lead to the jurisdiction and not in bar, he should have demurred specially, and assigned reason for that opinion for cause. The issue of fact was then suffered to go on to trial, and the plaintiff recovered only £30, although he shewed cause of action for above £50. Mr. Wylde, for the defendant, now moves to set aside the execution upon this verdict and to restore the fruits, upon the ground that his judgement in demurrer went to the whole cause of action; but I am of opinion that, as he should have entered his judgement on the record at Van Diemen's Land, and not have suffered the issue of facts to be tried to the plaintiff had paid his costs and amended his pleadings, this Court ought not to set the plaintiff's execution aside, after our return from the circuit, but ought to permit the plaintiff to amend the record now, upon payment to the defendant of his costs of a judgement on demurrer, of the amendment, and of this application."
By the Court. Rule discharged, upon the above terms.
[1] Judge Field presided over the Supreme Court, while the Judge Advocates at Hobart and Sydney presided over the two civil courts of limited jurisdiction, the Governor's and Lieutenant Governor's Courts. What was the jurisdictional relationship between these courts? See also Supreme Court of Civil Judicature, Judgment Rolls, 1817-1824, State Records N.S.W., 9/2231 (no. 410); Gavin v. Tims , 1821 above; and see Marsden v. Howe , 1818 above.
Site Publisher: Macquarie University, Sydney Australia | Last Updated: Tuesday, 14 June, 2011


Do you wish to speak French smoothly but uncertainty you can't speak it fluently in front of the peoples who know the language? If your answer is yes then don't take any tension try to help yourself by applying some of best tactics to improve your French lingo. Undergrads Learn the French language for some reason such as travel, work, family, carrier, and so on. As an adult aspirant, you definitely wish to learn the language efficiently under the guidance of experts who have varied years of experience in the French language then enroll your name in the best French language institutes in Delhi. In the class's environment, aspirants have to focus on the vocabulary, grammar, sentence structure, etc. If you learn any foreign language through classes you can achieve four key skills such as Listening, speaking, reading, and writing.
Set your goal what you actually want and need to know- As a learner, you need to set a target for yourselves and focused on your target and always try to achieve it with your dedication and hard works towards it. Once you start learning French you surely achieve your target.
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Repetition is key- You need to learn and practice everything's many times before you know them. You can repeat exercises, answer the similar questions, listen to the same sound files until you feel comfortable with them.
Learn together- Most of the people finds that learning with others helps keep them on track. If you are one of them who also learn the language with the help of other then you can be hiring a private tutors for you and learn the French language.
Every day learning- Make a habit of spending at least 15-30 minutes a day learning and/or practicing the French language.
Listen passively- You can get extra practice by listening to French during your regular activity walking, jogging, biking, cooking, and cleaning.
Try these useful tips to learn the French language without any difficulty you can indulge yourselves into the learning process of the French language. If you are French travel guides in Delhi then having knowledge of the French language you make your French travel feel more comfortable within your own country. If you verbally communicate the French language helps you to get to know another country culture, tradition, lifestyle, and customs and culture go hand in hand. If you get proper knowledge of the French language you obtain several carrier opportunities in various functional areas such as in the hospital, banks, school, college, hotel, travel agency, aviation, etc.
If you desire to become French language interpreters in Delhi then learning French lingo through renowned institute is the best option for you to learn the language with the help of highly qualified trainers and mentors.


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Why does Cardi B want a face tattoo? Elvis movie: Tom Hanks' 'thrilling' take on Colonel Tom Parker teased by Baz Luhrmann Horse racing tips: This juicy 49-1 Wednesday double catches the eye at Newbury and Plumpton I saved $500 on a plumber by using three common household products to make the sink drain faster The most popular soap stars on social media include a Peter Beale actor and former Hollyoaks star Candace Cameron Bure Pays Tribute to Bob Saget With New Heartbreaking Post This Multipurpose Oil Would Be Brooke Shields' Top 'Desert Island' Pick Five-year-old girl explains Partygate in hilarious video Chloe Brockett says Celebs Go Dating was like 'therapy' after dating disasters with bad boys and Jack Grealish scandal Was OAP, 86, killed by GANG that has been terrorising neighbourhood for years?
Home / Sport / John Cena reveals origins of 'You can't see me' taunt
John Cena reveals origins of 'You can't see me' taunt
Fox News Flash top headlines for January 13
Fox News Flash top headlines are here. Check out what's clicking on Foxnews.com.
John Cena rose to prominence in WWE during the company's ruthless aggression era, and when he developed his hip-hop gimmick, one of his patented taunts was "You can't see me."
Cena, who is the star of HBO's "Peacemaker," appeared on "The Tonight Show Starring Jimmy Fallon" on Tuesday and revealed the origins of how the move came to be.
John Cena competes with Triple H during the World Wrestling Entertainment Greatest Royal Rumble event in the Saudi coastal city of Jeddah on April 27, 2018.
(STRINGER/AFP via Getty Images)
John Cena at the 2014 International CES at the Encore Theater at Wynn Las Vegas on Jan. 8, 2014, in Las Vegas, Nevada
(Ethan Miller/Getty Images)
"Basically, on a dare, by absolute chance, I figured this wasn't visible enough (head bobbing). So I wanted to do this (hand moves in front of head). And the term 'you can't see me' was like, well you're not even on my level. And then like years later it overcame the meme culture and now it's literally I'm invisible."
While doing the media tour to promote the show, Cena landed on "The Ellen DeGeneres Show" and vowed his WWE career isn't over despite not performing on a show since September.
"WrestleMania is usually in the cusp of late March, early April. I don't know if I'm going to make it this year. And that's a good conundrum to have because there's a lot of good opportunity coming up, which I would love to take and if all those things line up, I don't know if I'll be able to make WrestleMania," he said, via Wrestling Inc.
John Cena enters the ring at the WWE SummerSlam 2015 at Barclays Center of Brooklyn on Aug. 23, 2015, in New York City.
(JP Yim/Getty Images)
"But I will tell you and everybody watching, I'm not done with WWE by a long shot. That's my home, I love it. I was able to go back during the summer for a few months and entertain audiences when they welcomed audiences back to arenas, so I've far from had my last performance."
Why does Cardi B want a face tattoo?


Legendary Pictures and Warner Bros.' new "MonsterVerse" is off to a better start than anyone thought possible. 2014's Godzilla earned over $529 million at the worldwide box office, while Kong: Skull Island has already bested that amount with $535 million after just over a month in theaters.
So it's safe to say that many fans are excited to see where this franchise is headed, and thankfully, it doesn't look like they'll have to wait very long to find out. Legendary Comics is starting a monthly comic book series called Skull Island: The Birth of Kong by writer Arvid Nelson and artist Zid. It serves as an official movie tie-in, meaning that whatever happens on the page is canon with the recent Kong: Skull Island and the sequels it has planned.
The main focus of the first issue is Aaron Brooks, the son of Houston Brooks (played by Corey Hawkins in Skull Island). The story reveals that Aaron joined Monarch (a secret monster-hunting organization) as an adult and led a secret mission to Skull Island in the early '90s, where he disappeared, and the book details that mission. The book also mentions Dr. Ishiro Serizawa, played by Ken Watanabe in Godzilla, which seems to indicate that he'll play a major role in the movies going forward.
There are also some other monsters who get highlighted in the first issue, namely Psycho Vultures, Leaf Wings, and Death Jackals; any one of which could pop up in a future film. And then there's the promise of learning more about Kong's origins, as well as some sick artwork showcasing a bunch of giant apes at war with the Skullcrawlers.
The first issue of Skull Island: Birth of Kong goes on sale in print and digital formats on April 12, 2017.
Jordan Vogt-Roberts Talks About Rejecting the First Pitch for 'Kong: Skull Island"


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2019 ACL Cornhole Mania Recap
I couldn't even wait a day to start writing about the 2019 ACL Cornhole Mania. I'm sitting here in the Atlanta airport waiting for a connecting flight and reminiscing on what was truly an unbelievable success. The word 'unbelievable' is so often used in hyperbole, but in describing this event the word can't be exaggerated. Just twelve months ago we were leaving Las Vegas after the 2018 ACL Cornhole Mania ecstatic with our 180 person event awarding $15,000 in cash prizes. At the time, it was our most successful event to date and it brought so much excitement and hope to the game of cornhole. Fast forwarding one year later, we are leaving the city of The Arch after awarding $60,000+ in cash prizes and organizing a seamless event for close to 800 players, not to mention the 24+ hours of ACL Digital Network coverage and the 5 hours of ESPN broadcasts.
On my first flight home I sat across the aisle from Jay Corley who was proudly carrying his and partner Tyler Poythress' trophies from their Advanced Doubles win. He got a good laugh from the passengers around us after the flight attendant told him he could not buckle-in his trophies in the empty seat beside him and would have to stow them in the overhead compartment. His response was "Oh c'mon, you know how hard I've worked for these?! I need to make sure they're safe". I chuckled along with the crowd but what he said was true. We have worked so hard for this. The ACL family has been training days, nights, and weekends for years for this type of opportunity, the type of opportunity that shows off the best cornhole players in the country in a positive light with national exposure. The type of opportunity to bring people of all different walks of life together under one roof to push aside differences to compete in a game that they love. I mean, where else are you going to see staunch liberal ACL Pro Scott Phillips and proud conservative ACL Pro Lester Price getting along, shaking hands, and having a few beers together? The players have trained, waited, and hoped for the sport that they love to reach these heights while giving them an opportunity to become professional athletes like the ones they adore on TV (well, close enough). The staff have trained, waited, and hoped to build an infrastructure that promotes growth in a sport that brings such happiness to this ACL family. Even I have trained, waited, and hoped for such an event that would leave me exhausted and sleep deprived but knowing with 100% certainty that the best is yet to come.
Well, enough of the sappy stuff. There were so many things that impressed me this weekend. With so much talent under one roof, we were bound to experience some of the best games of our short history. There were so many events all weekend, but I'm just going to stick to the four headliners for now.
My only pick of the weekend that won! My pick here was far from daring but Christine Papcke and Stacia Pugh played incredibly...as anticipated. They had to play the second and third best teams in their bracket and beat them both. Some of their wins were dominating, and some were nail-biters. The one constant in Papcke/Pugh all weekend was winning. It didn't matter if it took slide bag volleys, or timely clutch airmails, the ACL Pros got the job done. I could write plenty about their impressive performance but I really want to highlight the new faces that I saw in Women's Doubles; specifically, those two teams that attempted to stand in the way of Pugh and Papcke raised some eyebrows. First, you had the team of Brittany Koenig and Jessica Dover. These two ladies had never played a single tournament together before and went on an incredible run through the tournament. Candidly, the two of them told me they used to be bitter rivals in their region, but put aside their differences to see if they could compete with the top teams in the country. I think it's safe to say the rivalry has turned into an alliance. These two breezed through the tournament up until they ran into the other team that really impressed me this weekend, Brittany Emge and ACL Pro Kerry Mittermiller.
Stacia Pugh herself was "angry" with how well Mittermiller played, as the two know each other quite well and play often. Although Mittermiller didn't attempt many airmails, her slide, block, and push game were consistent and relentless. It also helped to have the single biggest eye-opening player from the weekend on the other end of the board. Time and time again, Emge blew me away. On the weekend, she had three different ridiculous shots to stay alive. Each time I doubted her (not because of her ability, but simply based on the statistical probabilities of each shot) and each time she came through with a jaw-dropping performance. I've seen plenty of incredible performances over the past nine years in cornhole, but never has an individual surprised me in a positive way as much as Emge did. What I expected to see from Emge and what I saw from Emge were two completely different sights. Honorable mentions to my shoutouts have to go to both Megan Maupin/Courtney Baird and Tammy Williams/Tiffany Fincham, who all made appearances on ESPN networks this weekend. Both teams come from proud areas of Northeast TN and Virginia, respectively, so I know they made many proud.
It looks like Adam Hissner and Cody Henderson finally decided to show up in a big way this season. They had a dominating performance against Lester Price and Greg Geary to the point that I didn't expect them to give up much in the final game. The problem was Adam Hissner gave the kiss of death with his "no one wants to play us" line in the post-match interview. Although I personally loved the quote, I think Hissner and Henderson perhaps forgot that Daymon Dennis and Philip Haydon were still in the tournament. Haydon and Dennis are unbelievable competitors. No matter the tournament, stakes, or conditions, these two just win games. Even after suffering a loss earlier in the day, these two fought through their loser's bracket and eventually won two straight against Trey Burchfield and Brandon Corwin. The two have such great chemistry, it's truly remarkable. At one point in the back-to-back wins against Corwin/Burchfield, Daymon Dennis was conflicted between a tough slide-around shot that could easily end off the board and simply settling for a board shot. Dennis wanted the simple board shot, but Haydon (with a little bit of fire) shouted down to his partner to "just listen to me and put the bag in the hole". There shouldn't be any surprised that Dennis followed up the exchange with a perfectly executed slide-around to earn a crucial two points late in the game. "Told ya" was the only further words exchanged by the Kentucky duo that game.
There were plenty of other impressive performances on the day, too. Eric Weathers and Josh Groce could not be any closer to winning a big tournament without actually winning one. They had two different opportunities to prevent Greg Geary and Lester Price from making yet another ESPN appearance but could not make it happen. They seemed to glide past all other opponents that day but just couldn't figure Geary and Price out (in fairness, not many have). Of course you also had Stacia Pugh and Chuckie Love who also came up one game short to Emory Parker and Matthew Sorrells. Pugh would have been the first female to make an ACL Pro Doubles semifinal, but Sorrells and Parker just continue to be the masters of bag manipulation. Between Sorrells' arsenal of shots and Parker's airmailing ability, the two are going to be tough to beat the rest of the season.
As I said, I sat next to Jay Corley on the plane and he was all smiles the entire flight. When I bumped into Corley during he and Poythress' incredible run, I asked him what he was doing to make such an improvement over the past 12 months. Just over a year ago, Corley was apart of the famous "Big 4" of Jamie Graham, Trevor Brooks, Tyler Poythress, and Jay Corley and I bluntly told him this weekend that back then, he was #4 out of 4. Now? He's a top ten, possibly top five player in the country. Corley plainly told me "that's what happens when you play [ACL Pro] Jordan Camba a lot". Poythress and Corley joined Matt Guy, Ryan Windsor, Matthew Sorrells, and Emory Parker as the most dominant players on the weekend, making the semifinals in at least two different events.
Two other teams that deserved some highlight reel attention were Shawn Anderson/Rob Guthary and ACL Pros Curtis Kearns/Trae Kelly. Anderson and Guthary were outrageous on airmails all weekend. Even in their last game of the day in which they lost, I thought they actually outplayed Matt and Bret Guy. They had some uncharacteristic mistakes late in the game that cost them the match but the fact that Rob Guthary had six four-baggers in that one match should tell you that he was in the zone. In another bracket, Kearns and Kelly were breaking hearts and hurting feelings all day long. I can't tell you how many times I was watching the bracket and said to myself "Kearns/Kelly beat ______ too?!" That's not an insult to them as a team, but more so a testament to the caliber of talent that they sent packing throughout the tournament. In the losers bracket alone, Kearns/Kelly defeated Michael Lucas Jr/Michael Dinges, Stephen Bolen/Noah Wooten, Trey Burchfield/Brandon Corwin, Adam Hissner/Cody Henderson, and Eric Weathers/Josh Groce...are you kidding me?!
The last event of the weekend may not have had a surprising ending, but there were certainly some intriguing performances. The day belonged to Ryan Windsor, there's no doubting that. I often used to say that when Matt Guy was in his zone, he was unbeatable. It wasn't as if Guy was always unbeatable, because sometimes he just wasn't in his zone. But when Guy was feeling good, I genuinely thought he was unbeatable. Well, that theory was debunked this weekend when Windsor defeated an "in-the-zone" Matt Guy in the semifinals. I lost count at how many 15/16 bag streaks we had throughout that one game that ended in a 21-20 victory for Windsor. I give ACL Pro Trey Burchfield an enormous amount of credit in the finals trying to force Windsor into a different style of play. Burchfield had executed such a great block-then-airmail game all weekend long, he came (relatively) close to a similar performance against Windsor, but Windsor was just too tough.
At the top of the list for surprises has to be Dustin Butler. Butler was certainly under the radar and widely unknown nationally coming into the weekend, but plenty of people know him after leaving. Butler only lost two games all day, both to Windsor, but delivered losses to Jay Corley, Chuckie Love, Daniel Resureccion (a great West Coast player that had a successful first ACL National appearance), and Courtney Coy. Another player that (finally) was able to live up to some steep expectations from me was ACL Pro Scott Phillips. Phillips started the day 4-0 and ended 5th in his bracket. Phillips also finished third in the Advanced Blind Draw with Thomas Tuttle so the Northwest Conference gets some recognition by way of its shining star in Phillips.
Can we leave for Arizona now? Well, maybe after a nap.


opinion This week, many prominent figures, political and commercial, gathered in that most august of locations, Australia's Parliament House, to launch what was lauded as a landmark report into the development of the nascent cloud computing industry in this nation.
The proceedings were opened by the Minister for Innovation, Industry, Science and Research, the Honourable Kim Carr, who exhorted Australia to be more than a "branch office" for cloud computing, but to aspire to something more. In this vein, Carr gravely informed onlookers, he had instructed his department to examine the cloud matter further.
Also attending was Greens Senator Scott Ludlam, whose calm and collected demeanour added a note of bipartisan support to the grand proceedings.
The commercial sector was represented by a cluster of eminent chief executives, flocking together in a tight cohort: Fujitsu's cheery Mike Foster; VMware's jovial Duncan Bennet, reserved Macquarie Telecom leader David Tudehope and Matthew Madden, the general manager of little-known cloud player InfoPlex. And I also received a lengthy statement on the matter from the Australian Information Industry Association.
Capping off the event was Nicholas Gruen of Government 2.0 fame, who, along with his colleague Simon Molloy, presented a lengthy report into Australia's cloud computing landscape and its potential for future development for fun and profit.
Now, as a prominent Australian technology journalist myself, I was forwarded many documents and statements from this majestic event attended by many titled dignitaries. I was invited to attend the ceremony, at which I was assured I would find many press opportunities and lofty personalities with whom I would find it fruitful to commune, over nibbles and in congenial surrounds.
And yet, I still have no real idea what the whole purpose of the whole shebang was.
I read through the speech at the event presented by Minister Carr, which I found contained many important adjectives and verbs. However, I do not believe the speech committed the good Senator or the government in general to any particular course of action. Perhaps Carr was filibustering?
I read through the report (PDF) presented by Gruen's organisation, Lateral Economics, which I enjoyed greatly with a cup of tea. However, as the report did not go into any particular detail about the nation's current cloud computing players (not even mentioning Optus or CSC, and barely mentioning Telstra), and sort of only politely seemed to request government assistance in the area, I'm not quite sure what it was about. Perhaps it merits further investigation?
I read through a very impressive media release issued by OzHub (PDF), which appears to be a gathering of Fujitsu, VMware, Macquarie Telecom and InfoPlex, which contained many resplendent statements about improving consumer and business confidence in the cloud. But at the end I wasn't quite sure what OzHub was aiming to achieve. Perhaps it's another industry association?
Speaking of industry associations, I also read through a statement on the launch by the venerable Suzanne Campbell, chief executive of the AIIA. "This is about systemic change: there is no one issue that will create the desired outcomes," argued Campbell. "Australia needs to take action on a number of fronts." I couldn't agree more. But what were the real issues? I didn't know.
I had a similar experience when I was sent another media release this week by another high-ranking Australian IT organisation, Data#3.
The release informed me that in order to serve its customers, the eminent Data#3 had invested in its own Australian cloud infrastructure. I'm not quite sure what sorts of products or services the company will offer using the infrastructure, nor am I sure of any of the details of how it has been built. Nor could I tell you what sorts of customers will be using it.
But I walked away with the impression that Data#3 is a superb company which is definitely doing something in cloud computing. The company's cloud computing strategy, I am sure, is most imposing — a strong, confident, bold march forward into the future. One that will help us all achieve our visions — whatever those might be.
After I had read all of this information, a certain quandary settled into my consciousness. What did it all mean, I wondered. Was there some overriding message which I was supposed to take from these events? Something about cloud computing? Something about Canberra? Something, perhaps, about the nature of the great game which corporations play with governments for favourable outcomes?
Was there something concrete to be learned?
Or could it be the case, that just like Rosencrantz and Guildenstern, all of the players in this week's drama were merely wandering around in a world beyond their control, unsure of their ultimate role but determined to make it clear that they were doing something? Was it just "a PR company gone mad"?
Can Australia lead global cloud market?
Does Australia need a cloud computing visionary?
The event simply exposed the fact that the Australian Government has awoken with a start from slumbering at the wheel of IT industry policy – Good heavens! Cloud Computing … well I never!
Still … better late than never … but we need to get our act together in terms of making more explicit connections between AGIMO's internal policy initiatives and DBCDE's industry policy programs and NBN adventures.
We need to avoid the temptation to 'dumb down' cloud computing by attempting to define it as only 'safe' when it is local. Competitive advantage will come instead from embracing the virtues of learning how to consume, create and manage highly secure borderless enterprise-grade multi-tenant systems environments – a field in which Google and Salesforce.com are world leaders. This is the future of the IT industry, and is a precursor to the ability to export cloud services.
This is where Australia needs to invest … not in persisting with a 'fat dumb and happy' approach based on the false illusion that IT is secure because it is on-shore. Remember Distribute.IT? Remember that the most recent scorecard vy the WA Auditor General failed 15 out of 15 agencies on security? The longer the Government continues to trumpet the 'only onshore is safe' story the slower we are as country to develop the thinking and skills needed to develop exportable cloud services. We need to learn to consume that which we seek to sell.
Great comment Steve! Sorry I am just catching up on this — missed it at the time ;) I agree completely with most of your sentiments here.
That photo is GOLD. Perfect match for the story but it's not credited?
heh cheers! I don't credit pictures unless I have to — in this case I licensed the shot from iStockPhoto, so I don't have to. That's where most of my uncredited pictures come from.


Languages have ways of expressing how, where, or when an event took place. Traditionally the expressions carrying this information are called ADVERBS.
6. Ideophones: these are a unique feature in Bantu languages. They are defined as the representation of an idea in sound, and some, but not all, are onamatopoeic, i.e., imitations of a sound. Most of the ideophones are adverbs; some of these have given rise to verbs. Nouns which are ideophones also exist, as, e.g.: pikipiki, motorcycle; tingatinga, tractor. Note also these ideophonic verbs: kupiga chafya, to sneeze; kupiga miayo, to yawn; kugugumiza, to stutter. One of the most common adverbial ideophones is fofofo (or sometimes foooo), used in two ways: kulala fofofo, to be sound asleep; amekufa fofofo, he is stone dead.
Examples of Swahili adverbs, grouped according to function, viz., Manner, Location, Time. Examples of their use are given. Sometimes there are multiple examples where one term is used for what in Euopean languages would require several different terms.
1.	M Adverbs of Manner.
Ilikuwa baridi mno.	It was extremely cold.
Tulitembea polepole.	We walked slowly.
Alifanya kazi upesi.	He worked fast.
Tuliimba sana.	We sang loudly.
Walifanya kazi sana.	They worked hard.
Niliumwa sana.	I had much pain.
Wageni walikaa sana.	The guests stayed a long time.
Gari lilikimbia sana.	The car was speeding.
Alisoma vizuri.	She read well.
Waliumia vibaya.	They were badly hurt.
Si vigumu kujifunza KiSwahili. It is not difficult to learn Swahili.
Amepumzika vya kutosha.	He has rested enough.
Amekula vya kutosha.	She has eaten adequately.
Amekula chakula cha kutosha. She has eaten enough food.
In any manner, anyhow, any way.
Fanya vyovyote uwezavyo.	Do it in any way you can.
Ameishi ovyo	He has lived an undisciplined life.
Usiache vyombo ovyo ovyo.	Don't leave the tools in a mess.
Alidhani mvua itanyesha, lakini mimi nilidhani vingine. She thought it would rain but I thought otherwise.
Ukisoma vile hawatakusikia. If you read like that, they won't hear you.
Aliweka mzigo wake chini, nami nilifanya vivyo hivyo.
He put his load down, and I did exactly the same.
Baada ya safari alikuwa amechoka; vilevile wenzake walisikia uchovu sana.
After the journey he was tired; his companions were likewise.
Walifanya kazi kwa haraka.	They worked fast.
Walikutana kwa siri.	They met secretly.
Tuliwapokea kwa furaha.	We welcomed them heartily.
Nilisoma barua yaka kwa makini. I read your letter carefully.
Kwa kawaida hufika saa mbili kila asubuhi. She usually comes at eight every morning.
Alinieleza kwa kifupi habari za ajali. He briefly described the accident to me.
Aliendelea kusema kwa kirefu. He kept on talking at length.
Alieleza kwa kirefu.	He explained fully.
Vilivunjika kwa urahisi.	They broke easily.
Sijui kama amepata nyumba au chumba; kwa vyovyote amepata mahali pa kukaa.	I don't know if she got a house or a room; in any case she found a place to stay.
Like/as in a verb construction with relative particle.
Chota maji kadiri uwezavyo (or, unavyoweza). Draw as much water as you can.
Alitupa mkuki mbali alivyoweza.	He threw the spear as far as he could.
Usome vizuri iwezekanavyo (or, inavyowezekana). Read as well as possible.
Niliangalia jinsi alivyoshona nguo.	I watched how she sewed the garment.
Peleka viti nje.	Take the chairs outside.
Wageni walitoka mbali.	The guests came from far away.
Jirani anakaa karibu.	A neighbour lives nearby.
Wameacha mizigo juu.	They have left the loads upstairs.
Nilianika nguo chini.	I spread out the clothes on the ground.
Wazee wako ndani.	The old people are inside.
Amerudi nyuma.	He has gone backwards.
Endelea mbele.	Keep going forward.
Chukua karatasi, uchore picha katikati. Get paper and draw a picture in the centre.
Funga vijiti pamoja.	Tie the sticks together.
Watoto walibaki nyumbani.	The children stayed at home.
A list of these adverbial nouns could be expanded almost endlessly : mjini, nchini, mtoni, etc.
Hayupo hapa, umtafute kwingine.	She is not here; look for her somewhere else.
Wamesafisha pote.	They have cleaned everywhere.
Kokote aendako, hawezi kuacha nafsi yake nyuma. Wherever he goes, he can't leave himself behind.
Karibu kwetu!	Welcome to us (our place)!
Nilisikia pana matatizo penu.	I heard there are problems at your place.
Huku tunakokaa kuna milima mingi.	Around here where we live there are many mountains.
Yupo pale.	She is over there.
Nilisoma katika kitabu.	I read in a book.
Tumepata barua toka Dodoma.	We have received a letter from Dodoma.
Walikwenda mpaka mtoni na kurudi. They went as far to the river and back.
Nimeanika nguo kwenye kamba.	I have hung the clothes on the line.
Tulikaa chini ya mti.	We sat under a tree.
Wamejenga choo karibu na nyumba.	They have built a latrine near the house.
(Place) where, in verb constructions with a relative particle of location.
Pale palipofyekwa panapendeza. There where the grass was cut it looks nice.
Kijijini tulikokwenda kulikuwa na mashamba mazuri. In the village where we went there were nice farms.
Kabatini wanamoweka nguo nilikuta mende wingi. In the cupboard where they put their clothes, I found many cockroaches.
Tupo Morogoro sasa.	We are at Morogoro now.
Zamani kulikuwa na nyumba huku. Formerly, there was a house here.
Tutafyeka majani kwanza, halafu tutayakusanya. We shall cut the grass first; later we will gather it up.
Kwanza tutajifunza, baadaye tutacheza. We shall study first, later we will play.
Kwanza tutajifunza, tutacheza baadaye.We shall study first and play later.
Alifua nguo, kisha alizipiga pasi. She washed the clothes, then she ironed them.
Again; when following a negative verb, it means "any more"
Amerudi tena.	She has come back again.
Hatarudi tena.	She won't come back any more.
Namsikia daima anapiga mluzi.	I always hear him whistling.
Hufurahi sikuzote.	She is always happy.
Yafaa kutibu magonjwa mapema. It is good to treat illnesses in good time.
Haifai kusafiri usiku.	It is no good to travel at night.
Like the noun usiku, night, all other nouns designating times of day, or days, weeks, months, years, can be used as time adverbs e.g. jana, yesterday; leo, today; kesho, tomorrow; alfajiri, dawn; asubuhi, morning; adhuhuri, noon; alasiri, afternoon (early part); jioni, late afternoon, evening; usiku, night-time …. after darkness has fallen.
Mtoto alizaliwa karibuni.	The child was born recently.
Wataondoka karibuni.	They will leave soon.
Alivuka barabara, hapo akakanyagwa. He crossed the road, then he got run over.
Pengine mvua huanza mwezi huu, pengine inachelewa. Sometimes the rain begins in this month; sometimes it is late.
Alisema atakuja leo; pengine amesahau. She said she would come today; maybe she has forgotten.
Tumengoja tangu asubuhi.	We have waited since morning.
Amekuwa na ugonjwa huu tokea utoto wake. She has had this illness since her childhood.
Alifanya kazi mpaka usiku.	She worked until night.
In, within (a span of time), approximately. Can be used only in reference to time.
Alizaliwa mnamo mwaka 1954. She was born in 1954.
Nilipokwenda mjini nilikutana na rafiki yangu. When I went to town, I met my friend.
Waliporudi walioga.	When they returned, they had a bath.
Kila wanapokwenda Mikumi wanaona simba. Every time they go to Mikumi, they see lions.
Mtoto huyu ni mkubwa mno.
This child is extremely large.
Only adverbs of Manner will enter into the sort of combinations cited above.
Adverbs modifying verbs may be of any type: Manner, Location, or Time. They have a relatively fixed order of occurrence in relation to one another; there is some flexibility but within specific limits.
Alisoma vizuri. She read well.
Wanajifunza masomo yao kwa bidii. They learn their studies diligently.
Kwa kawaida huchemsha maziwa. Usually (they) boil the milk.
Kwa vyovyote atazidi kuugua asipomeza dawa yake. In any case, she will get worse (more ill) if she doesn't take her medicine.
Walikaa chini ya mti. They sat beneath the tree.
Alikula chakula chake hapa. She ate her food here.
Tutaondoka kwenda Mwanza asubuhi. We will leave to go to Mwanza in the morning.
Asubuhi tutaondoka kwenda Mwanza. In the morning we will leave to go to Mwanza.
Watoto walicheza vizuri hapa jana. The children played well here yesterday.
Wanafunzi walijifunza hapa kwa bidii jana. The students studied here diligently yesterday.
Walijifunza vizuri chini ya mti jana. They studied well under the tree yesterday.
Jana walijifunza vizuri chini ya mti. Yesterdaythey studied well under the tree.
Asubuhi alisoma kitabu chake kwa makini sana chini ya mti huu. In the morning she read her book carefully under this tree.
5.	Notice that in all cases when there is a noun object in the sentence it comes after the verb and before the adverbs.


George J. Porto, age 69, of Waupaca passed away at home surrounded by family on Sunday, February 10, 2019. George was born September 23, 1949 at Saint Elizabeth Hospital in Appleton.
George spent 32 years in law enforcement including the last ten as Crime Reduction Coordinator for the City of Menasha Police Department. George was an unusually good listener and an ever-ready dispenser of sage advice for family and friends. He loved listening to early jazz and was proud of the vast record collection he built. He had a keen eye for photography. His photos of Wisconsin scenes were painted and sold through the business he and his wife built. One of their favorite paintings was of George's photo of the Red Mill in Waupaca where he and Barby were married almost 30 years ago. He loved fly fishing, especially on the Radley Creek that flowed behind the beautiful home he and his wife designed for their retirement. He gave generously of his time to the Friends of Hartman Creek State Park where he and Barby loved to hike. Papa was adored by his children and grandchildren. Above all else, he loved and cherished his wife whom he called "Princess." Practical, strategic, generous, honest, fair, patient and kind-hearted; he lived well, loved and is loved much.
He will be greatly missed by wife, Barbara (Scherzinger) Porto; mother-in-law, Tommie Scherzinger; stepchildren, Jennifer Sensenbrenner of Los Angeles, CA; James (Jennifer) Sensenbrenner of Appleton; Carrie (Kurt) Schmitz of Elk River, MN; Charles (Leah) Sensenbrenner of Waupaca; and Douglas (Melody) Sensenbrenner of Oahu, HI; daughter, Kathy Cloutier of Hustisford, WI; grandchildren: Alice, Jeremy, Brittany, Khiah, Emma, Dyani, Gracyn, Keller, Priya and Sylvie; great-grandchildren: Eli, Dakota, and Riley; and sisters, Ceal (Jim) Tesch of Neenah and Edie (Ken) Dickrell of Appleton.
Preceded in death by his parents, Anthony J. Porto and Irene (Miller), brother Martin, brother Gregory, sister Toni Lauer, sister Miki Ryder.
A Memorial Service will be held on Friday, February 15, 2019 at Saint Mary Magdalene Catholic Church in Waupaca at 4 PM, with Father Xavier Santiago, officiating. Memorial Visitation will be held at the church from 2 PM until the time of service at the church. In lieu of flowers, a memorial fund has been established in his name.
George's family would like to give special thanks to Dr. Matthias Weiss and his team at ThedaCare Oncology for fighting hard for hope, to the ThedaCare Hospice team as well as Maple Crest Funeral Home for providing comfort when needed most, and to Father Xavier whose guidance helped bring us peace.
George, we will keep your song in our hearts and we will look for your shining star to brighten our way.


With initial support in the form of grime veteran Plastician, "Birmingham's finest" Emalkay gained the attention of South London based label Boka Records with the warped, future bass drones and epic strings of Gut Feeling. Continuing the success, Testing The Waters EP was released in October 2006 followed by Monsters in June 2007.
The revolutionary sound of Mecha, released in the fall of 2007, gained Emalkay support from the likes of Radio 1 DJ Mary Anne Hobbs and breakbeat pioneer FreQ Nasty, as well as many of the leading figures of the current dubstep scene. It seemed Emalkay's own potential as a pivotal dubstep artist was finally being realised. His final release on Boka Records was the reggae influenced My Story in April 2008.
In the fall of 2008, Emalkay produced Explicit - a tune that gradually captured the interest of such prominent dubsteppers as Benga and received major support from acts such as The Scratch Perverts and drum and bass duo Chase and Status. After being approached by Caspa however, the track was finally released on the Dub Police label in February 2009 after much anticipation.