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Video transcript available at https://www.youtube.com/watch?v=HvzxznYOhQM.
Quick Facts: Social Workers
2021 Median Pay
Typical Entry-Level Education
See How to Become One
Work Experience in a Related Occupation
Number of Jobs, 2021
Job Outlook, 2021-31
9% (Faster than average)
Employment Change, 2021-31
What Social Workers Do
Social workers help people prevent and cope with problems in their everyday lives.
Social workers are employed in a variety of settings, including child welfare and human service agencies, healthcare providers, and schools. Most work full time, and some work evenings, weekends, and holidays.
How to Become a Social Worker
Social workers typically need a bachelor's or master's degree in social work from a program accredited by the Council on Social Work Education. They also may need a license; specific requirements vary by state.
Clinical social workers need a master's degree, supervised clinical experience, and a license from the state in which they practice.
The median annual wage for social workers was $50,390 in May 2021.
Overall employment of social workers is projected to grow 9 percent from 2021 to 2031, faster than the average for all occupations.
About 74,700 openings for social workers are projected each year, on average, over the decade. Many of those openings are expected to result from the need to replace workers who transfer to different occupations or exit the labor force, such as to retire.
Explore resources for employment and wages by state and area for social workers.
Compare the job duties, education, job growth, and pay of social workers with similar occupations.
More Information, Including Links to O*NET
Learn more about social workers by visiting additional resources, including O*NET, a source on key characteristics of workers and occupations.
What They Do ->
What Social Workers Do About this section
Child and family social workers protect vulnerable children and support families in need of assistance.
Social workers help individuals, groups, and families prevent and cope with problems in their everyday lives. Clinical social workers diagnose and treat mental, behavioral, and emotional problems.
Social workers typically do the following:
Identify people and communities in need of help
Assess clients' needs, situations, strengths, and support networks to determine their goals
Help clients adjust to changes and challenges in their lives, such as illness, divorce, or unemployment
Research, refer, and advocate for community resources, such as food stamps, childcare, and healthcare, to assist and improve a client's well-being
Respond to crisis situations such as child abuse and mental health emergencies
Monitor clients' situations, and follow up to ensure that they have improved
Maintain case files and records
Provide psychotherapy services
Social workers help people cope with challenges in their lives. They help with a wide range of situations, such as adopting a child, being diagnosed with a terminal illness, or preventing and treating substance abuse.
Some social workers get involved at a broad level to help community organizations and policymakers develop or improve social programs, services, and conditions. This is sometimes referred to as macro social work.
Advocacy is an important aspect of social work. Social workers advocate or raise awareness with and on behalf of their clients and constituents. Additionally, they may advocate for the social work occupation on local, state, and national levels.
Social workers who are licensed to diagnose and treat mental, behavioral, and emotional disorders are called clinical social workers (CSW), licensed clinical social workers (LCSW), or have a similar title; specific titles vary by state. They provide individual, group, family, and couples therapy; work with clients to develop strategies to change behavior or cope with difficult situations; and refer clients to other resources or services, such as support groups or other mental health workers. Clinical social workers may develop treatment plans with the client, doctors, and other healthcare workers and may adjust the treatment plan if necessary based on their client's progress. They may work in a variety of specialties.
The following are examples of types of social workers:
Child and family social workers protect vulnerable children and help families in need of assistance. They help families find housing or services, such as childcare, or apply for benefits, such as food stamps. They intervene when children are in danger of neglect or abuse. Some help arrange adoptions, locate foster families, or work to reunite families.
School social workers work with teachers, parents, and school administrators to develop plans and strategies to improve students' academic performance and social development. They help students with problems such as aggressive behavior or bullying. Additionally, school social workers meet with families to discuss issues such as access to special education resources or frequent student absences.
Healthcare social workers help clients understand their diagnosis and adjust their lifestyle, housing, or healthcare. For example, they may help people transition from the hospital to their homes and communities. In addition, they may provide information about services, such as home healthcare or support groups, to help clients manage their illness or disease. Social workers help doctors and other healthcare workers understand the effects that diseases and illnesses have on clients' mental and emotional health. Some healthcare social workers specialize in geriatric social work, hospice and palliative care, or medical social work.
Mental health and substance abuse social workers help clients with mental illnesses or addictions. They provide information on services, such as support groups and 12-step programs, to help clients cope with their illness. These workers often are licensed clinical social workers.
<- Summary Work Environment ->
Work Environment About this section
Although most social workers work in an office, they may spend a lot of time away from the office visiting clients.
Social workers held about 708,100 jobs in 2021. Employment in the detailed occupations that make up social workers was distributed as follows:
Child, family, and school social workers 349,800
Healthcare social workers 179,500
Mental health and substance abuse social workers 119,800
Social workers, all other 59,000
The largest employers of social workers were as follows:
Individual and family services 18%
Local government, excluding education and hospitals 15
Ambulatory healthcare services 14
State government, excluding education and hospitals 14
Most social workers work in an office setting. They may spend time visiting clients and meeting with colleagues and community specialists or other support workers. School social workers may be assigned to multiple schools and travel around the school district to see students. Understaffing and large caseloads may cause the work to be stressful.
Social workers, all other have one of the highest rates of injuries and illnesses of all occupations. ("Social workers, all other" includes criminal justice social workers, adult protective service social workers, and forensic social workers, among other titles.)
Most social workers are employed full time. They sometimes work evenings, weekends, and holidays to see clients or attend meetings, and they may be on call.
<- What They Do How to Become One ->
How to Become a Social Worker About this section
Clinical social workers need a master's degree, supervised experience, and a license to provide mental health or counseling services.
Most social workers need either a bachelor's or a master's degree from a program accredited by the Council on Social Work Education.
A bachelor's degree in social work (BSW) is the most common requirement for entry-level nonclinical social worker positions. BSW programs teach students about diverse populations, human behavior, social welfare policy, and ethics in social work. All programs require students to complete supervised fieldwork or an internship.
Clinical social workers typically need a master's degree in social work (MSW). These programs prepare students for work in their chosen specialty by developing clinical assessment and diagnostic skills. Some nonclinical social workers also may complete master's-level programs. MSW programs generally take 2 years to complete and include a supervised practicum or internship.
A bachelor's degree in social work is not required in order to enter a master's degree program in social work. Although a bachelor's degree in almost any field is acceptable, common majors include public policy and social services, psychology, or social science. Recommended coursework includes sociology, economics, and political science. Some programs allow graduates with a bachelor's degree in social work to earn their master's degree in under 2 years.
After obtaining an MSW degree, clinical social workers must complete supervised training and experience. The length of clinical training varies by state but may take several years.
All states require clinical social workers to be licensed. Some states also require nonclinical social workers to have a license or credential.
Becoming a licensed clinical social worker requires a master's degree in social work from an accredited program and supervised clinical experience after graduation. After completing their supervised experience, clinical social workers must pass a clinical exam to be licensed.
Because licensing requirements vary by state, those interested should contact their state licensure board. For more information about regulatory licensure boards by state, visit the Association of Social Work Boards.
Important Qualities
Communication skills. Clients talk to social workers about challenges in their lives. To provide effective help, social workers must be able to listen to and understand their clients' needs.
Compassion. Social workers often work with people who are in stressful and difficult situations. To develop strong relationships, they must have patience and empathy for their clients.
Interpersonal skills. Social workers must be able to work with different groups of people. They need to foster healthy and productive relationships with their clients, colleagues, and other support specialists.
Organizational skills. Social workers must help and manage multiple clients, often assisting with their paperwork or documenting their treatment.
Problem-solving skills. Social workers must analyze their clients' complex situations and develop practical solutions.
<- Work Environment Pay ->
Pay About this section
Median annual wages, May 2021
Counselors, social workers, and other community and social service specialists
Total, all occupations
Note: All Occupations includes all occupations in the U.S. Economy.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics
The median annual wage for social workers was $50,390 in May 2021. The median wage is the wage at which half the workers in an occupation earned more than that amount and half earned less. The lowest 10 percent earned less than $36,520, and the highest 10 percent earned more than $82,840.
Median annual wages for social workers in May 2021 were as follows:
Social workers, all other $61,190
Healthcare social workers 60,840
Child, family, and school social workers 49,150
Mental health and substance abuse social workers 49,130
In May 2021, the median annual wages for social workers in the top industries in which they worked were as follows:
Local government, excluding education and hospitals $61,190
Ambulatory healthcare services 58,700
State government, excluding education and hospitals 48,090
Individual and family services 46,640
<- How to Become One Job Outlook ->
Job Outlook About this section
Percent change in employment, projected 2021-31
Source: U.S. Bureau of Labor Statistics, Employment Projections program
Projected employment of social workers varies by occupation (see table). Child and family social workers will be needed to work with families to strengthen parenting skills, prevent child abuse, and identify alternative homes for children who are unable to live with their biological families. However, employment growth of child, family, and school social workers may be limited by federal, state, and local budget constraints.
Healthcare social workers will continue to be needed to help aging populations and their families adjust to new treatments, medications, and lifestyles.
Employment of mental health and substance abuse social workers will grow as more people seek treatment for mental illness and substance abuse. In addition, drug offenders are increasingly being directed to treatment programs, which are staffed by these social workers, rather than being sent to jail.
Employment projections data for social workers, 2021-31
SOC Code
21-1020 708,100 772,100 9 64,000 Get data
Child, family, and school social workers
21-1022 179,500 199,300 11 19,900 Get data
Mental health and substance abuse social workers
Social workers, all other
21-1029 59,000 60,700 3 1,700 Get data
<- Pay State & Area Data ->
State & Area Data About this section
Occupational Employment and Wage Statistics (OEWS)
The Occupational Employment and Wage Statistics (OEWS) program produces employment and wage estimates annually for over 800 occupations. These estimates are available for the nation as a whole, for individual states, and for metropolitan and nonmetropolitan areas. The link(s) below go to OEWS data maps for employment and wages by state and area.
Projections Central
Occupational employment projections are developed for all states by Labor Market Information (LMI) or individual state Employment Projections offices. All state projections data are available at www.projectionscentral.com. Information on this site allows projected employment growth for an occupation to be compared among states or to be compared within one state. In addition, states may produce projections for areas; there are links to each state's websites where these data may be retrieved.
CareerOneStop includes hundreds of occupational profiles with data available by state and metro area. There are links in the left-hand side menu to compare occupational employment by state and occupational wages by local area or metro area. There is also a salary info tool to search for wages by zip code.
<- Job Outlook Similar Occupations ->
Similar Occupations About this section
This table shows a list of occupations with job duties that are similar to those of social workers.
ENTRY-LEVEL EDUCATION
Health Education Specialists and Community Health Workers
Health education specialists develop programs to teach people about conditions affecting well-being. Community health workers promote wellness by helping people adopt healthy behaviors.
See How to Become One $48,860
Marriage and Family Therapists
Marriage and family therapists help people manage and overcome problems with family and other relationships.
Master's degree $49,880
Probation Officers and Correctional Treatment Specialists
Probation officers and correctional treatment specialists assist in rehabilitation of law offenders in custody or on probation or parole.
Bachelor's degree $60,250
Psychologists study cognitive, emotional, and social processes and behavior by observing, interpreting, and recording how individuals relate to one another and to their environments.
Rehabilitation counselors help people with physical, mental, developmental, or emotional disabilities live independently.
School and Career Counselors and Advisors
School counselors help students develop academic and social skills. Career counselors and advisors help people choose a path to employment.
Social and community service managers coordinate and supervise programs and organizations that support public well-being.
Social and Human Service Assistants
Social and human service assistants provide client services in a variety of fields, such as psychology, rehabilitation, and social work.
High school diploma or equivalent $37,610
Substance Abuse, Behavioral Disorder, and Mental Health Counselors
Substance abuse, behavioral disorder, and mental health counselors advise people on a range of issues, such as those relating to alcoholism, addictions, or depression.
<- State & Area Data More Info ->
Contacts for More Information About this section
For more information about social workers and clinical social workers, visit
Association for Community Organization and Social Action
School Social Work Association of America
For more information about accredited social work degree programs, visit
Council on Social Work Education
For more information about licensure requirements, visit
Association of Social Work Boards
Occupational Requirements Survey
For a profile highlighting selected BLS data on occupational requirements, see
Mental health and substance abuse social workers (PDF)
For career videos on social workers, visit
Child, family, and school workers
Medical and public health social workers
O*NET
<- Similar Occupations
Bureau of Labor Statistics, U.S. Department of Labor, Occupational Outlook Handbook , Social Workers,
at https://www.bls.gov/ooh/community-and-social-service/social-workers.htm (visited January 16, 2023).
Last Modified Date: Thursday, September 8, 2022
The What They Do tab describes the typical duties and responsibilities of workers in the occupation, including what tools and equipment they use and how closely they are supervised. This tab also covers different types of occupational specialties.
The Work Environment tab includes the number of jobs held in the occupation and describes the workplace, the level of physical activity expected, and typical hours worked. It may also discuss the major industries that employed the occupation. This tab may also describe opportunities for part-time work, the amount and type of travel required, any safety equipment that is used, and the risk of injury that workers may face.
The How to Become One tab describes how to prepare for a job in the occupation. This tab can include information on education, training, work experience, licensing and certification, and important qualities that are required or helpful for entering or working in the occupation.
The Pay tab describes typical earnings and how workers in the occupation are compensated—annual salaries, hourly wages, commissions, tips, or bonuses. Within every occupation, earnings vary by experience, responsibility, performance, tenure, and geographic area. For most profiles, this tab has a table with wages in the major industries employing the occupation. It does not include pay for self-employed workers, agriculture workers, or workers in private households because these data are not collected by the Occupational Employment and Wage Statistics (OEWS) survey, the source of BLS wage data in the OOH.
The State and Area Data tab provides links to state and area occupational data from the Occupational Employment and Wage Statistics (OEWS) program, state projections data from Projections Central, and occupational information from the Department of Labor's CareerOneStop.
The Job Outlook tab describes the factors that affect employment growth or decline in the occupation, and in some instances, describes the relationship between the number of job seekers and the number of job openings.
The Similar Occupations tab describes occupations that share similar duties, skills, interests, education, or training with the occupation covered in the profile.
Contacts for More Information
The More Information tab provides the Internet addresses of associations, government agencies, unions, and other organizations that can provide additional information on the occupation. This tab also includes links to relevant occupational information from the Occupational Information Network (O*NET).
The wage at which half of the workers in the occupation earned more than that amount and half earned less. Median wage data are from the BLS Occupational Employment and Wage Statistics survey. In May 2021, the median annual wage for all workers was $45,760.
Additional training needed (postemployment) to attain competency in the skills needed in this occupation.
Typical level of education that most workers need to enter this occupation.
Work experience that is commonly considered necessary by employers, or is a commonly accepted substitute for more formal types of training or education.
The employment, or size, of this occupation in 2021, which is the base year of the 2021-31 employment projections.
The projected percent change in employment from 2021 to 2031. The average growth rate for all occupations is 5 percent.
The projected numeric change in employment from 2021 to 2031.
Employment Change, projected 2021-31
Growth Rate (Projected)
The percent change of employment for each occupation from 2021 to 2031.
Projected Number of New Jobs
Projected Growth Rate
The projected percent change in employment from 2021 to 2031.
U.S. Bureau of Labor Statistics Office of Occupational Statistics and Employment Projections PSB Suite 2135 2 Massachusetts Avenue NE Washington, DC 20212-0001
Telephone: 1-202-691-5700 www.bls.gov/ooh Contact OOH
Community and Social Service


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Multi Vitamins is a stereotyped medication Nigerians take to feel better and supposedly increase the vitamins in their system. Well, the question is, how good are multi-vitamins intake?
On YourViewTVC this morning, a nutritionist in person of Babatunde Soteye spoke at length, addressing this issue along side the ladies of #aYourViewTVC.
According to him,multi-vitamins are compounds needed in the body in small quantity.They are thus needed only whenever there is a deficiency in the body.
He further explained that it can be overdosed and abused in cases like that of a pregnant woman taking folic acid, people using multi-vitamins to get fats and parents using it as nutrition for their children.
To correct this,he advised that adequate balanced diet i.e good proportion of the six classes of food and vegetables should be taken daily to supply the body the amount of vitamins needed instead of taking multi-vitamins. He added that over-cooking of vegetables reduce the nutrients in them and this can be avoided by just washing the vegetables mildly with salt before cutting and cooking.
He concluded by advising people to stop self medication and get a health care provider.


text:
import React, { Component, PropTypes } from 'react'
import { connect } from 'react-redux';
import withStyles from 'isomorphic-style-loader/lib/withStyles';
import s from './SparqlList.scss';
import Interpretation from '../Interpretation';
import {pushQueries} from "../../actions/qanary_push";

@connect((store) => {
  return {
    question: store.qa.question,
    SPARQLquery: store.qa.SPARQLquery,
    SPARQLqueryKB: store.qa.SPARQLqueryKB,
    SPARQLqueryConfidence: store.qa.SPARQLqueryConfidence,
    namedGraph: store.qa.namedGraph,
    language: store.lang.language,
    knowledgebase: store.knowledgebase.knowledgebase,
  }
})
class SparqlList extends Component {

  static propTypes = {

  };

  constructor(props) {
    super(props);
    this.state = {
      query: false, //indicates if the answer or the query is displayed
      selectedQuery: false,
    };
    this.handleClick = this.handleClick.bind(this);
    }

  static contextTypes = {
    owner: PropTypes.element,
  }

  handleClick() {
    this.setState({query: !this.state.query}); //on click switch from query to answer
  }

  handleClick2(selectedquery, index, e){
    console.log("This is the sparql queries list:",this.props.SPARQLquery);
    var replacedsparql = [].concat(this.props.SPARQLquery) ;
    replacedsparql[0].query = this.props.sparqlquery[index].query; //replace the first query with the selected query
    replacedsparql[0].score = this.props.sparqlquery[0].score; //increase its score
    replacedsparql[0].confidence = this.props.sparqlquery[index].confidence;
    replacedsparql[0].kb = this.props.sparqlquery[index].kb;
    replacedsparql.splice(index, 1); //remove the selected query from where it was in the list before
    console.log("This is the updated sparql queries list: ",replacedsparql);
    this.props.dispatch(pushQueries(replacedsparql,this.props.language,replacedsparql[0].kb,this.props.namedGraph))
  }

  render() {
    console.log("LIST",this.props.sparqlquery);
    return (

          Q

              {(this.state.query) ?

                  {this.props.sparqlquery.map(function (newitems, index) {
                    return (

                        <input type="radio" className={s.sparqlmenu} name = "selectquery" value = {newitems.query} onClick={this.handleClick2.bind(this, newitems.query,index)}/>

                          <Interpretation id={index} index={index}/>

       {newitems.query}

)
                        }.bind(this))
                  }

 : null
              }

    );
  }

}
export default withStyles(SparqlList, s);

redpajama_set_name: RedPajamaGithub


The automotive industry is the second largest user of biocomposites in the European Union, after the construction sector.
Every year the European car industry uses around 80,000 tonnes of wood and plant fibres in composites.
Instead of synthetic fibres like glass, biocomposites use natural fibres for reinforcement.
Biocomposites help reduce vehicle weight, which improves performance and reduces fuel consumption, cutting CO2 emissions. They can also be less energy insensitive to produce and easier to recycle, than alternatives.
Currently, most biocomposites are used in car interiors, but in the future they could also be used for semi-structural and structural applications.
A study in India, reported similar figures for jute, kenaf, sunn hemp and flax fibres, and concluded that the carbon footprint for the production of natural fibres is 20—50% less than glass fibres. But these figures only get the fibres to the factory doors – they don't cover the impact of producing or using the composites.
A market report on the use of biocomposites in the European Union in 2012.
Information on the Soybean Car from The Henry Ford, a large museum complex in Detroit, founded by Henry Ford.


text:
Q: Spark Scala Delete rows in one RDD based on columns of another RDD I'm very new to scala and spark and not sure how to start.
I have one RDD that looks like this:
1,2,3,11
2,1,4,12
1,4,5,13
3,5,6,12

Another that looks like this:
2,1
1,2

I want to filter the first RDD such that it will delete any rows that are matching the first two columns of the second RDD. The output should look like:
 1,4,5,13
 3,5,6,12

A: // input rdds
val rdd1 = spark.sparkContext.makeRDD(Seq((1,2,3,11), (2,1,3,12), (1,4,5,13), (3,5,6,12)))
val rdd2 = spark.sparkContext.makeRDD(Seq((1,2), (2,1)))

// manipulate the 2 rdds as a key, val pair
// the key of the first rdd is a tuple pair of first two fields, the val contains all the fields
// the key of the second rdd is a tuple of first two fields, the val is just null
// then we could perform joins on their key
val rdd1_key = rdd1.map(record => ((record._1, record._2), record))
val rdd2_key = rdd2.map(record => (record, null))

// 1. perform left outer join, the record become (key, (val1, val2))
// 2. filter, keep those records which do not have a join
// if there is no join, val2 will be None, otherwise val2 will be null, which is the value we hardcoded from previous step
// 3. get val1
rdd1_key.leftOuterJoin(rdd2_key)
  .filter(record => record._2._2 == None)
  .map(record => record._2._1)
  .collect().foreach(println(_))

// result
(1,4,5,13)
(3,5,6,12)

Thanks

A: I personally prefer dataframe/dataset way as they are optimized forms of rdd and with more inbuilt functions and similar to traditional databases.
following is the dataframe way:
First step would be to convert both of the rdds to dataframes
import sqlContext.implicits._
val df1 = rdd1.toDF("col1", "col2", "col3", "col4")
val df2 = rdd2.toDF("col1", "col2")

Second step would be to add a new column in dataframe2 for filtering condition checking
import org.apache.spark.sql.functions._
val tempdf2 = df2.withColumn("check", lit("check"))

And final step would be to join the two dataframes, filter and drop the unnecessary rows and columns.
val finalDF = df1.join(tempdf2, Seq("col1", "col2"), "left")
                          .filter($"check".isNull)
                          .drop($"check")

You should have final dataframe as
+----+----+----+----+
|col1|col2|col3|col4|
+----+----+----+----+
|3   |5   |6   |12  |
|1   |4   |5   |13  |
+----+----+----+----+

Now you can either convert to rdd using finalDF.rdd or you can continue your further processing with dataframe itself.
I hope the answer is helpful

redpajama_set_name: RedPajamaStackExchange


Fireball Mail bluegrass band - Winners of the 2016 Telluride Bluegrass Festival Band Contest - started performing as a band in early 2014. The group embodies a unique combination of instrumental virtuosity and prolific songwriting talent impressing audiences with not only their cutting edge delivery, but also with an impressive catalog of fresh and original material. Collectively, Fireball Mail has an extensive resume of touring, and recording experience including appearances with such notable artists as Buddy Greene, Claire Lynch, Curtis Burch, and Ricky Skaggs.
The Band released their debut recording, "Bending the Rails" in June of 2016. With stacks of new, original material, Fireball Mail plans to share more music on the road and in the studio in 2018.
Brad Bulla was born and raised in Greensboro, North Carolina with an early exposure to bluegrass/acoustic music. All it took was attending one Doc and Merle Watson concert as a young boy and he was hooked! After teaching himself to play on a pawn shop guitar and banjo, Brad began performing at festivals, fairs and concert venues, eventually picking his way to become Western Open Flatpick Guitar Champion, and runner up at the Indiana State Banjo Championship.
Brad formed a band and eventually performed in every state except Maine and Alaska, opening shows for some of Country and Bluegrass Music's biggest names including Merle Haggard, Restless Heart, Jim and Jesse McReynolds, Ray Price, Randy Travis, Charlie Pride, and Ricky Skaggs. Brad came to Nashville in 1999, established a Radio Promotions Company promoting artists such as Ricky Skaggs, The Del McCoury Band, and Blue Highway.
Along with performing with Fireball Mail, Brad operates Bulla Promotions - a promotion and management company based in Nashville, Tennessee.
Multi-instrumentalist Phil Easterbrook began his journey into bluegrass music in Colorado Springs, Colorado. Phil has played banjo, guitar and resonator guitar in bluegrass bands since 1976. As a featured player in both "The Reasonable Band" with David Harvey and the "Heartland Band", based out of Colorado, Phil has performed at many national level events in the western region such as the Telluride Bluegrass Festival, Rocky Mountain Bluegrass Festival, the Kerrville Bluegrass Festival and the Rocky Grass Festival.
Phil relocated to the Huntsville, Alabama area in 1999 and started to get integrated into the local acoustic music scene. From 2002 through 2005, Phil toured, played banjo, guitar, and singing harmony as a member of the Claire Lynch Band.
Phil has also recently released two solo CD projects, Rainy Day Sessions and Acoustic Christmas, which feature Phil on all of the instruments and vocals.
Phil operates a project recording studio, Rocket City Roots in Huntsville, Alabama and specializes in acoustic music production.
Joe Brown hails from Eva, Alabama has been a musician nearly all his life starting out on drums at the age of five, then moving to saxophone, and on to guitar. The bluegrass bug bit him when he played with his Dad's band filling the bass slot and frequently performing in their local church.
Joe drew his bluegrass inspiration from The Del McCoury Band and the influences of Tony Rice. He specifically credits Mike Bub, Todd Phillips, Barry Bales, and Roy Husky, Jr as his personal favorite masters of the upright bass. Joe has performed in numerous band configurations and shared the stage with Claire Lynch, Trey Hensley, and Jason Eskridge. Joe is quick to make the point that he is thrilled to be in the Fireball Mail Band and is enjoying a musical adventure beyond his wildest dreams.
Tyler has been a professional touring fiddle player since 2000. When it comes to creativity, rhythm, chopping, bluegrass and American folk music, Tyler is one of the main go-to fiddle players in Nashville. It's no wonder with three grandmaster traditional fiddle championships under his belt!
Tyler also is one of the hottest upcoming claw hammer banjo players of middle Tennessee. Along with several state championships including Tennessee, Alabama, Kentucky, and Georgia, he is also the current and 3 time national claw hammer banjo champion.


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To work with a bunch of ales or something larger - that is the question which faces several business owners. However some people don't realize that it can be a question that is inquired not just by business owners but homeowners who are accomplishing repair or construction focus on their homes. Even tho it's a medium sized small business or a big home project you might want to look at a garbage 5 Yard Dumpster Rental in Mulga, AL.
You may not set wet colour into the dumpster but you're able to set dry colour cans inside of it.
Men and women require 5 Yard Dumpster Rental in Mulga, AL providers for many factors. For example, a landlord usually needs to thoroughly clean the condo where the last tenants eventually left garbage piled higher. A professional house renovator often takes several visits to the county dump. Or maybe, you just have an enormous cleaning activity to do and you also need a spot to dispose each of the waste materials. Normally, renting of the king-size garbage containers will be the region of huge construction companies, but right now there many 5 Yard Dumpster Rental in Mulga, AL businesses that rent large dumpsters (also referred to as roll offs) to frequent people likewise. Hiring rotate off dumpster can be a great choice for anybody who does not want garbage as the hurdle in the way of receiving the job done.
This 5 Yard Dumpster Rental in Mulga, AL guide sets out each important factor to consider when figuring out to rent a roll-off pot. It offers strategies for customers hunting to rent a quality as well as affordable dumpster because of their construction project, and also shows questions you should be asking yourself when contemplating which company to rent from.
These rotate off dumpsters are one of the most popular sizing used amid home owners. They're great for eliminating excess junk after handling some normal maintenance on the house, particularly when redecorating or cleaning out bedroom in the basement.
If you are professionally working on your own home with regards to design, you want to preserve as much dollars as you can. Most likely your family and friends tend to be helping you together with the remodeling of your dwelling. This is a good way for family as well as friends to get together in this ever so busy earth.
You may preserve pennies right here, but it needs large sum of cash to be used on your health issues in your not to distant future because disposing such a big waste about self requires a lot of effort, physical exertion as well as time expense as well. Besides this you need to focus on travelling complexities as well as environmental warm and friendly recycling connected with disposed squander if you are individual who respects societal concerns of the nation. Construction waste is often in big quantities as well as occupies a lot of space. Daring to apparent construction squander on home not only consumes your time nevertheless occupies your current free room for longer stretch of time.
If you are excitedly planning on remodeling your kitchen compared to you have been active picking out brand new kitchen cabinets, brand new flooring, maybe new kitchen appliances and more. With your large kitchen area remodeling work you will definitely require to rent a dumpster to remove all of the trash.
If you own a restaurant and therefore are remodeling your bath room than you definitely will need a dumpster or a number of dumpsters. You will possibly need the big dumpster(s) that can hold up to some tons. Four tons is concerning ten pickup truck loads. Based on the size of your current restaurant as well as the extent of the remodeling, will depend on the size of leased dumpster that you will need.
When choosing the dumpster company for you to rent from, make certain they offer things to search for. If you need a dumpster morning, the company should be able to honor your current wishes.
Perhaps you are adding your bathrooms onto your home or business. You will also have to rent a dumpster to keep the remodelling running punctually and easily. You will probably only need to rent a tiny dumpster for this challenge as it will hold up to a pair of tons.
You will be updating a bath room in your modern day home. Rent the dumpster to pitch out a cheap flooring, vanities or shower casings. You will be happy that you have a dumpster rented when you or your company can promptly throw the many big debris out rather than tripping into it or organizing it on your lawn and making one major mess. Others do not want to begin to see the mess for a few weeks when you're remodeling your home.
Denver is amongst the most populated areas inside of Colorado and with population happens the issue involving dump throw away and hence it is collection and transportation for you to dump websites becomes pertinent. Companies and the ones need the solutions of dumpster corporations and these corporations can be rental on individual or company basis. Dumpster accommodations that are regionally sponsored are usually dependable, pre-screened and reasonably priced. The services are provided simply by either entrance load 5 Yard Dumpster Rental in Mulga corporations or rotate off jar rentals. The actual rentals are often used for house renovations, downstairs room clean outs and dry wall projects. The area 5 Yard Dumpster Rental in Mulgas are responsible for connecting individuals and companies for you to dump throw away collection and transport carrier's networks.
Every challenge is made less complicated and easier with quick waste removal. Cleaning out the shed and removing unnecessary broken tools such as outdated rakes and scoops can be done swiftly without having to pile the trash out by the road and hope how the local waste pickup takes the entire pile. You can grab the guesswork from cleaning out your current garage, downstairs room, or eliminate by eliminating the necessity to use nearby trash pick up. Construction assignments are also possible as one dumpster are equipped for old home equipment, drywall, lavatory fixtures, sprained metal and broken goblet. Simplify your home projects simply by calling or ordering online a Maryland 5 Yard Dumpster Rental in Mulga.
your investment transforms to be the best when it can get the right product or service. When we talk about the trash discretion, none other than 5 Yard Dumpster Rental in Mulga include the right fit, here are the reasons precisely why? Dumpster rental for waste disposal could keep you out from the unnecessary danger that is taken care of in throwing the trash. You do not leave your current busy daily activities and travel to another area to dump the trash.
Nowadays not just households however lots of company and private corporations make use of these services. It happens to be all about usefulness. So whether it is garbage through your house separation or work place management, simply relax and pay attention to the rubbish going away hotel an eco-friendly way.
The thing is, do-it-yourself projects create trash. Plenty of trash. You have shredded picture, broken drywall and the never ending assortment of lasagna boxes and broken furnishings. If you stacked all that inside a pickup truck would certainly be running for you to dump three or four times every day. That's okay in concept, but when you are working your home improvements around your current work schedule and every moment counts you don't want to lose hours of time pulling your waste around.
Many people may go their entire day-to-day lives without ever needing to get into 5 Yard Dumpster Rental in Mulga, AL. Others might do it each day. But for those who work in between, it might seem like a bit of a labyrinth while deciding precisely how to go about it. Perhaps you have a huge event in the planning and need a means to dispose of every one of the trash. You may be planning a big demolition and need a fast place to store debris if you don't take countless outings to the dump. Whatever the reason, you'll find people that will help you get precisely what you need. Here are a few hints that might help you get began.
Most dumpster debt collectors in this area are generally professional with what they do. The masai have a good history, years of providing these services inside a most immediate and skilled way. It is very rear to receive residents and also users of the services in the area making grievances about the companies they receive. The inhabitants here have complete trust in the effort done by nokia's offering these services.
The style of environmental concern is currently echoed by number of industries and also business agencies across the US. Quite a few construction sectors in the US are creating "green" product options, encouraging a great many others to go green to defend the environment. Where by do they then get the organic material via? They use post-consumer and also post-industrial waste because raw materials for production of these kinds of recyclable goods. They are involved in giving 2nd life to the particular waste got rid of by inhabitants of US.
Summer season is another fun time for universities to be re-designed. Many initiatives can be carried out and improved upon while the college students are off of school. Educators and college students will be stunned when they return back to school whatsoever of the developments made. If you are living in a warm climate and want inside remodeling done on your school compared to winter break is a great time period to get this done. All of the youngsters and professors should be out from the school generally.
Improper weightlifting of the huge waste on to your truck may lead to back soreness, leg and also arm soreness, acute injury, and other really serious chronic effects. The hospital prices paid to treat such accidents will double that the person has stored by removing the trash on own. In the end the person will end up spending huge sum of money in addition to suffering.
Often after huge parties or even home remodeling projects, people are left with the job of removing their own waste materials. If there isn't a trash go away location regional, this can become very inconvenient. Besides, who desires to make various trips hauling trash around, hoping to locate a suitable area to leave it? In actuality all you'll have to complete is obtain the dumpster and also throw ones garbage in it. The remainder is left up to the company.
Rental Time period: Normally 5 Yard Dumpster Rental in Mulga, AL companies will allow you to maintain dumpsters for 5 - 7 days to weeks while there are some companies which give up to 2 1 week times nevertheless these companies are quite less and hard to found. In case you keep your dumpster in excess of permitted time frame than you actually again want to pay additional amount. You will be charged on day to day which can range between $5 to $15 per day. Making it advisable to pay attention to rental period and in order to may well avoid from additional payment.


dendritic cells (DCs) and monocytes. During SLE, the immunogenicity of monocytes and DCs is significantly up-regulated, promoting the activation of self-reactive T cells. Accordingly, it is important to understand the contribution of these cells to the pathogenesis of SLE and the mechanisms responsible for their altered functionality during disease. One of the key enzymes that control monocyte and DC function is haem oxygenase-1 (HO-1), which catalyses the degradation of the haem group into biliverdin, carbon monoxide and free iron. These products possess immunosuppressive and anti-inflammatory capacities. The main goal of this work was to determine HO-1 expression in monocytes and DCs from patients with SLE and healthy controls. Hence, peripheral blood mononuclear cells were obtained from 43 patients with SLE and 30 healthy controls. CD14+ monocytes and CD4+ T cells were sorted by FACS and HO-1 expression was measured by RT-PCR.


1. Preheat oven to 200°C. Place the goat's cheese on a baking tray with a walnut half on each. Drizzle some olive oil and scatter on the thyme leaves and season with black pepper. Bake in the oven until the cheese has melted from the inside.
2. Crush the rest of the walnuts. Shred the salad before adding to a bowl. Add the crushed walnuts.
3.In a separate bowl mix the lemon juice with oil. Grate in the apple and season with salt and pepper. Drizzle a little vinaigrette over the salad and toss together.
4.Use a chef's ring to cut the toast into 4 round croutons.
5.To serve, arrange the dressed walnut salad onto serving plates. Place the crouton on the salad and top with the goat's cheese. Spoon over the remaining vinaigrette and serve.


text:
A Grand Survey of Latin American Art is Coming to Kunstmuseum Bern
Balasz Takac
After World War II, Latin America became the site of rapid economic, social, and political shifts followed by the development of the mass media and mass culture. Namely, between the 1950s and 70s, numerous countries of the area were exposed to local and international conflicts. As some of them were under the rule of military dictatorships, artists naturally reflected these hardships in their works. Regardless of the media, the majority of the works created during the mentioned period share one thing in common - the artists' quest for utopia.
Challenged by the very notion of utopia at the current time, Kunstmuseum Bern decided to organize a group exhibition titled Tools for Utopia that establishes a dialog between the past and present domains of Latin artists and their experimental practices.
Left: Ana Mendieta - Untitled (Glass on Body Imprints)	1972, Iowa (Estate print 1997). Suite of six estate color photographs	50.7 x 40.5 cm each. Photographer: Peter Schälchli, Zürich. Copyright © 2020, ProLitteris, Zurich. Courtesy Daros Latinamerica Collection, Zürich / Right: Liliana Porter - Untitled, 1973 (original b/w negative) / 2003 (digital print). B/w photograph	33 x 33 cm. Photographer: Peter Schälchli, Zürich. Copyright the artist. Courtesy Daros Latinamerica Collection, Zürich
Juxtapozing Past and Present
The exhibition curator Marta Dziewańska focused on examining what the term tools meant in a historical context of art production aiming to transcend representation by exposing the artwork in nonconventional spaces so that it becomes an active agent of social transformation.
Observing closely different artistic strategies of resistance seems more than adequate in the time of a global pandemic, civil rights, and climate crisis. Nina Zimmer, Director of the Kunstmuseum Bern, said:
Not only in Latin America, which is suffering severely from the Coronavirus crisis, but everywhere on the globe, people are asking how our societies must evolve socially and politically going forward. Tools for Utopia is looking for ways in which the accumulated memory storage of Latin American art can inspire and activate us today.
Paz Errázuriz - Evelyn I, 1987. Gelatin silver print on fiber base paper, 30.6 x 43 cm. Photgrapher: Paz Errázuriz, Santiago de Chile. Copyright: © 2020, ProLitteris, Zurich. Courtesy Daros Latinamerica Collection, Zürich
The upcoming exhibition will bring more than two hundred works by artists from Argentina, Brazil, Chile, Colombia, Cuba, Guatemala, Mexico, Venezuela, and other countries.
On display there will be the historic works by Ana Mendieta, Liliana Porter, Mira Schendel, Gego, Hélio Oiticica, Carlos Cruz-Diez, and Jesús Rafael Soto, while the contemporary works will include artists Paz Errázuriz, Doris Salcedo, Belkis Ayón, Teresa Margolles, Juan Manuel Echavarría, Miguel Ángel Rojas, and others who explore the body as a political tool.
Left: Luis Camnitzer - Coca-Cola Bottle / Right: Manifesto ruptura (Lothar Charoux, Waldermar Cordeiro, Geraldo de Barros, Kazmer Féjer, Leopoldo Haar, Luiz Sacilotto, Anatol Władysław), 1952. Offset lithograph, 32.9 × 21.9 cm. The Museum of Fine Arts, Houston, The Adolpho Leirner Collection of Brazilian Constructive Art, museum purchase funded by the Caroline Wiess Law Accessions Endowment Fund, 2007.16 © Família Cordeiro
Tools for Utopia at Kunstmuseum Bern
The mentioned dialog between the historical works and contemporary ones tends to underline the continuity of the urge to critically dissect the social reality and pose questions regarding the role Latin American art movements of the mid-20th century had in the realm of political imagination and what their activity meant for the later generations.
The exhibition is accompanied by a publication that will bring newly commissioned conversations with the artists and a selection of historical manifestos.
Tools for Utopia will be on display at Kunstmuseum Bern from 24 November 2020 until 21 March 2021.
Antonio Dias - To the Police, 1968. Bronze, 3 parts:approx. 7.5 x 12.5 x 12.5 cm, 9 x 14.5 x 14.5 cm, 8 x 11 x 11 cm (Text). Photgrapher Peter Schälchli, Zürich. Copyright © 2020, ProLitteris, Zurich. Courtesy Daros Latinamerica Collection, Zürich.

redpajama_set_name: RedPajamaCommonCrawl


text:
Families of all sizes on the Norwegian Gem – NYC to Canada
Pool deck on Norwegian Gem
ABOARD THE NORWEGIAN GEM (DAY 2) — Linda Montana and her sister surprised their mom with this cruise on the Norwegian Gem up to Canada to celebrate her 75th birthday.
They've left husbands and kids behind, and brought along a cousin of their mom. That they don't have to worry about anyone but themselves on this girl's trip "is the best part," said Montana, sitting at the pool in the sunshine.
Monica Colistra, meanwhile is traveling with four other lifelong friends from Long Island to celebrate their 70th birthdays. "We're as close as sisters," she says from her perch in the hot tub.
Sports area and climbing wall on Norwegian Gem
And Karen Neff is cruising with her husband, one of her four children and their two young children. Other cruises, she says, there have been as many as 20 of them, including all 10 grandchildren ranging from 13 to eight months.
She books the luxurious Haven villas, which she believes is a better bet than bringing the kids on a luxury liner. "We have all the amenities," she explains, " But the kids have a lot more to do."
I meet a lot of grown kids traveling with parents. "A lot of us with a lot of college debt can't otherwise afford vacations," said Aubrey Neff, 35, traveling with her mom from Minneapolis, adding that she's never been to New York (where we sailed from yesterday) or to New England and Canada, where we are sailing to.
We're traveling with my husband's brother and sister in law; others are in larger family groups but as school has just started, there aren't many kids.
"We're talking about doing this every year, " said Myra Feeney, one of the "birthday girls. " "We're having a blast."
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City lights. No cameras. Lots of action.
Peru: Person-To-Person Culinary Experiences In The Inca World
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Dat kun je doen door de titel van een bepaald nummer e It was produced by Brian Hughes and Loreena McKennitt. The Visit is the fourth studio album by Loreena leased in 1991 the album has been certified four times platinum in Canada gold in the United States. It is the song that really made Loreena McKenit famous.
Mummers' plays are folk plays performed by troupes of amateur actors wrenboys, refers particularly to a play in which a number of characters are called on stage, guisers ( also by local names such as rhymers, two of whom engage in a combat, pace- eggers, soulers, known as mummers , tipteerers, traditionally all male the loser being revived by a doctor ze top 50 meditatie- muziek kun je hier beluisteren ( & download- instructies) Je kunt deze meditatie- muziek zelf downloaden. Stream ad- free with Amazon Music Unlimited on mobile desktop tablet. Listen to your favorite songs from Loreena McKennitt.
What people do not realize is that she put. Loreena mckennitt mummers dance download. Many people have heard the radio version of " Mummer' s Dance". Download our mobile app now.
The album was a cowinner with the compilation album Saturday Night Blues, of the 1992 Juno Award for Best Roots Traditional Album of the Year. Listen to your favorite songs from The Journey So Far - The Best Of Loreena McKennitt by Loreena McKennitt Now.
Many people have heard the radio version of " Mummer' s Dance". It is the song that really made Loreena McKenit famous. What people do not realize is that.
The Visit is the fourth studio album by Loreena leased in 1991, the album has been certified four times platinum in Canada and gold in the United States. It was produced by Brian Hughes and Loreena McKennitt.
The album was a cowinner, with the compilation album Saturday Night Blues, of the 1992 Juno Award for Best Roots and Traditional Album of the Year. Listen to your favorite songs from Loreena McKennitt. Stream ad- free with Amazon Music Unlimited on mobile, desktop, and tablet.
Download our mobile app now. Listen to your favorite songs from The Journey So Far - The Best Of Loreena McKennitt by Loreena McKennitt Now.
Many people have heard the radio version of " Mummer' s Dance". It is the song that really made Loreena McKenit famous.
What people do not realize is that she put.


text:
AS Kpéténé Star is een Centraal-Afrikaanse voetbalclub uit de hoofdstad Bangui. Ze spelen in de Première Division, de nationale voetbalcompetitie van het land.

Centraal-Afrikaanse voetbalclub
Bangui

redpajama_set_name: RedPajamaWikipedia


Birthdays or anniversaries; one thing that makes the occasion grand is a cake. So, if you are planning to give a cake to someone on their special day; which type of cake are you picking? Have you ever put much thought in the cakes you choose to give? Apparently, cakes are delicious but they can meaningful too if you do some brainstorming before you gift one.
Whether you Send cake online or give a cake in hand by yourself; the cake has to be perfect. Maybe there is no perfect human being in the world; but there can be a perfect cake for a person. A perfect cake is one that is scrumptious, filling and as per the choice of the eater. Following are a few instances that might help you in making a better choice in picking a perfect cake for someone.
If you are choosing a cake for elderly people then you can stick to fruit flavours or simply fruit oriented cakes. It is so because fruit would be good for their health and there is higher chance that they love fruit. Maybe the fancy cake flavour you pick might not get relished by them. So, why not give something to them that they can relate to and make the most of? Now here you can give them scrumptious pineapple cake, mango cake, mixed fruit cake and cake with fruit slices filled. These cakes taste wonderful and feel really refreshing. They will definitely like the fruit aspect of the cake.
Whether you believe it or not these teenagers are always after looks, style and exotic aspect. If you give them a cake that is absolutely delicious but not really aesthetic in appearance; they might show a thumbs down to it. But if you give them a cake that is really stylish in looks it would be an instant hit for them. There are myriad of options in cakes that you can choose. You can relate the cake to their liking and interests. For example, if the receiver loves to play musical instruments, you can find a cake in the shape of piano; if they like beach, you can pick a cake that looks like a beach or if the person likes to capture pictures then giving a cake in the shape of camera would be an absolute delight.
If you want to give a cake to your parents on their wedding anniversary but don't know what really should be given; you can go for a delicious photo cake. You can pick a cake that is absolutely stylish, exotic and mouth-watering but equally engaging. The engaging element in that cake would be sentiments and you can bring that touch through a picture. You can take one of their best pictures and get it engraved in the cake. The cake would have a photo of them and hence they are going to be on cloud nine on seeing this.
So, whether you are giving a cake by hand or you will send cakes by post; these are a few things that can make your choice amp and apt.


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Immunisation helps protect you and your family/whānau against many vaccine preventable diseases. Children receive a series of free vaccines, usually at their general practice. It is very important that vaccines are given at the correct time to protect people who are most vulnerable to illness, especially children and older people. All children in NZ are eligible for the funded National Schedule vaccines. Your general practice team will send a reminder when you or your child are due for immunisation.
Influenza or flu is a major threat to health, because it can spread rapidly through families and communities. Many won't feel sick at all, but can still pass the flu virus onto others. The influenza vaccine is free for all pregnant women, anyone from six months old with certain medical conditions, and anyone aged 65 years or over. Ask your Practice Nurse or GP if you are eligible.
Contact: Your general practice team or go to Immunisation for Life for more information.
The acute demand service provides short-term assessments, treatment and support to patients who may have been otherwise admitted to or have been recently discharged from hospital. Patients are referred by either their GP or the hospital.
A team of nurses can provide treatment, such as administering IV (intravenous) antibiotics or assessing your medical condition.
Contact: Ask your nurse before you leave hospital or check with your GP team.
GP visits are free for people with a terminal illness in the last 3-6 months of life. This includes home visits and after hours visits.
These services include a free consultation in your home or at a pharmacy with a pharmacist to help you better understand and manage your medications.
Contact: Talk to your GP team.


text:
Зиринг () град је у америчкој савезној држави Ајова. По попису становништва из 2010. у њему је живело 554 становника.

Демографија
Према попису становништва из 2010. у граду је живело 554 становника, што је 63 (10,2%) становника мање него 2000. године.

Извори

Спољашње везе

Градови у Ајови
Википројект географија/Насеља у САД


text:
module ActsAsEventOwner
  module Core
    def self.included(base)
      base.send :extend, ClassMethods
    end

    module ClassMethods
      def acts_as_event_owner options = {}
        include InstanceMethods

        class_eval do
          has_many :event_specifications, :class_name => ActsAsEventOwner::EventSpecification.name, :as => :owner, :dependent => :destroy
          has_many :events, :class_name => ActsAsEventOwner::EventOccurrence.name, :as => :owner, :readonly => true do
            def generate(options={})
              proxy_owner.event_specifications.find(:all, :conditions => "until IS NULL OR until >= '#{Time.zone.now.to_s(:db)}'").each {|spec| spec.generate_events(options)}
              self.reload
            end

            def <<(obj)
              raise ActsAsEventOwner::Exception.new("Do not add events directly- add event specifications, then call events.generate")
            end

            def build(attributes={})
              raise ActsAsEventOwner::Exception.new("Do not build events directly- build event specifications, then call events.generate")
            end

            def create(attributes={})
              raise ActsAsEventOwner::Exception.new("Do not create events directly- build event specifications, then call events.generate")
            end

            def upcoming
              find(:all, :conditions => ["start_at >= ?", Time.zone.now])
            end

            def past
              find(:all, :conditions => ["start_at < ?", Time.zone.now])
            end
          end
        end
      end
    end

    module InstanceMethods
    end
  end
end


text:
Petrizzi est une commune de la province de Catanzaro en Calabre (Italie).

Administration

Hameaux
Campo, La Pietà

Communes limitrophes
Argusto, Centrache, Chiaravalle Centrale, Gagliato, Montepaone, Olivadi, San Vito sullo Ionio, Satriano, Soverato

Évolution démographique

Lien externe
 Galerie de photos sur Petrizzi

Notes et références

Petrizzi


"I'm bored…." Have we ever heard anything like this before?
As the school year is upon us, life is picking up again. We've got carpools, school projects, grocery shopping, holiday-preparing, and there's not much time (or money) for big extravagant entertainment. Everyone's looking for a way to unwind and have some quality family time.
Take a breath and think positively about limits on time or money. You don't need a blow-up fun house to have a great game night with family and friends! I have sixteen fun and easy game night ideas for your family and friends.
Play with words. Bananagrams is a fun easy game you can take anywhere. Think of it as a portable "scrabble" game.
Play with shapes and get creative. Cut out giant circles with the corresponding Twister colors and play Twister in your living room. You can get creative and move the circles. Who needs a traditional Twister board?
Go on a magazine scavenger hunt in your house. This is a great way to sort through old magazines too! Come up with 12-15 items you are looking for. Examples may include an inspirational phrase, a picture of a backpack, the word "glow", a blue dress, an article written by two people – anything goes! Sit around the kitchen table with a stack of magazines, scissors in hand, set a timer and GO! You can make this a learning activity. Ask the kids to search for five bits of interesting trivia. It's a great way to share, learn, and connect.
Charades – Ah, a game that never gets old. It's a wonderful way to get active, thinking, and learn each other's "favorites". You can have themes and ask each person to pick their favorite movie or food. A great getting-to-know-you-better activity!
Don't count out classic game. Monopoly, Battleship, and Sorry are all fun games for all ages. Game makers also make Junior versions for the younger kids if the classic version is too difficult.
Card Games. My kids love card games. When they were little we played Old Maid, War, and Go Fish. Now we play Gin Rummy and Hearts.
Mexican Train. A domino game where you build "tracks" for your train. A great game for kids over 8 and adults.
Dominos. My grandfather played dominos with me every Saturday. He was very competitive and I believe he cheated. But I loved it as a child. Dominos is terrific to teach kids counting and sorting. And fun for adults to outwit each other.
Yahtzee. Another fabulous game to teach counting and sorting. A simple game of dice; the goal is to roll particular sets of numbers with the dice. Whoever finishes with the most points wins.
Jenga. Stack the blocks carefully. Roll the dice. Gently remove your block. Make the tower fall and you are out!
Pictionary. Great fun for the family. Draw a picture and wait for the silly guesses to start. It is a family favorite.
Scattergories. Roll the die for a letter. Set the timer. Try answer the categories with a word starting with the rolled letter.
Taboo. Get your team mates to guess the secret word. The twist? You can't use any of the forbidden (taboo) words. Players get creative and silly.
Wii Just Dance Series – These games are so fun. They get the group up and moving, laughing, and having a great time. Your dancing will embarrass your teens and the little ones will think you are cool. It's a win-win.
You Don't Know Jack – This game is like a comedy show, multiple choice answer game. The game comes in a game pack with console, PS4 game, and for download on mobile devices. Connect your mobile devices with the app, sync to the television, and start to play. They are trivia questions with hilarity.
Are You Smarter Than A 5th Grader? Looking to give your kids an ego boost? Play this game with them. Not only am I not smarter than a 5th grader, I didn't make it past Kindergarten. My kids still tease me about it. It is a lot of fun to play a game where the kids have the upper hand. It comes in a classic board version, Nintendo, and Xbox.
Have a hilarious and fun game night. Get creative, laughing, and hungry planning to your night of fun.
Amy Oestreicher is a 28 year old actress, musician, teacher, composer, dancer, writer, artist, yogi, foodie, and general lover of life. Surviving and thriving through a coma, 27 surgeries and other trauma has inspired Amy to share her story with the world through her passionate desire to create and help others. Piecing her life together after her initial dreams of performing musical theatre took on a beautiful detour into broader horizons. Amy has written, directed and starred in a one woman musical about her life, Gutless & Grateful, has flourished as a mixed media and acrylic artist, with her art in multiple galleries and mounting dozens of solo art shows, and continues to share her story through her art, music, theatre and writings.
More information on her unique story, as well as her creative ventures can be found at amyoes.com, and visit her blog for her newest art, music and inspirational musings. You can also visit her Etsy shop.


text:
Genetics →
Genetic Conditions →
Cleidocranial dysplasia
URL of this page: https://medlineplus.gov/genetics/condition/cleidocranial-dysplasia/
Cleidocranial dysplasia is a condition that primarily affects development of the bones and teeth. Signs and symptoms of cleidocranial dysplasia can vary widely in severity, even within the same family.
Individuals with cleidocranial dysplasia usually have underdeveloped or absent collarbones, also called clavicles ("cleido-" in the condition name refers to these bones). As a result, their shoulders are narrow and sloping, can be brought unusually close together in front of the body, and in some cases can be made to meet in the middle of the body. Delayed maturation of the skull (cranium) is also characteristic of this condition, including delayed closing of the growth lines where the bones of the skull meet (sutures) and larger than normal spaces (fontanelles) between the skull bones that are noticeable as "soft spots" on the heads of infants. The fontanelles normally close in early childhood, but they may remain open throughout life in people with this disorder. Some individuals with cleidocranial dysplasia have extra pieces of bone called Wormian bones within the sutures.
Affected individuals are often shorter than other members of their family at the same age. Many also have short, tapered fingers and broad thumbs ; flat feet ; knock knees ; short shoulder blades (scapulae); and an abnormal curvature of the spine (scoliosis ). Typical facial features include a wide, short skull (brachycephaly ); a prominent forehead ; wide-set eyes (hypertelorism ); a flat nose; and a small upper jaw.
Individuals with cleidocranial dysplasia often have decreased bone density (osteopenia) and may develop osteoporosis , a condition that makes bones progressively more brittle and prone to fracture, at a relatively early age. Women with cleidocranial dysplasia have an increased risk of requiring a cesarean section when delivering a baby, due to a narrow pelvis preventing passage of the infant's head.
Dental abnormalities are very common in cleidocranial dysplasia and can include delayed loss of the primary (baby) teeth; delayed appearance of the secondary (adult) teeth; unusually shaped, peg-like teeth; misalignment of the teeth and jaws (malocclusion); and extra teeth , sometimes accompanied by cysts in the gums.
In addition to skeletal and dental abnormalities, people with cleidocranial dysplasia may have hearing loss and are prone to sinus and ear infections. Some young children with this condition are mildly delayed in the development of motor skills such as crawling and walking, but intelligence is unaffected.
Cleidocranial dysplasia occurs in approximately 1 per million individuals worldwide. It is likely underdiagnosed because many affected individuals have mild signs and symptoms.
Cleidocranial dysplasia is usually caused by mutations in the RUNX2 gene. This gene provides instructions for making a protein that is involved in the development and maintenance of teeth, bones, and cartilage. Cartilage is a tough, flexible tissue that makes up much of the skeleton during early development. Most cartilage is later converted to bone (a process called ossification), except for the cartilage that continues to cover and protect the ends of bones and is present in the nose, airways, and external ears.
The RUNX2 protein is a transcription factor, which means it attaches (binds) to specific regions of DNA and helps control the activity of particular genes. Researchers believe that the RUNX2 protein acts as a "master switch," regulating a number of other genes involved in the development of cells that build bones (osteoblasts) and in the development of teeth.
The RUNX2 gene mutations that cause cleidocranial dysplasia reduce or eliminate the activity of the protein produced from one copy of the RUNX2 gene in each cell, decreasing the total amount of functional RUNX2 protein. This shortage of functional RUNX2 protein interferes with the normal development of bones, cartilage, and teeth, resulting in the signs and symptoms of cleidocranial dysplasia. In rare cases, individuals with a deletion of genetic material that includes RUNX2 and other nearby genes may experience additional features, such as developmental delay, resulting from the loss of these genes.
In about 30 percent of individuals with cleidocranial dysplasia, no mutation in the RUNX2 gene has been found. The cause of the condition in these individuals is unknown.
Learn more about the gene associated with Cleidocranial dysplasia
This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. Some affected individuals inherit the mutation from one affected parent . Often the parent is mildly affected, and in some cases had not previously been recognized as having the disorder. Other cases result from new mutations in the gene . These cases occur in people with no history of the disorder in their family.
Other Names for This Condition
Cleidocranial dysostosis
Dento-osseous dysplasia
Marie-Sainton syndrome
Additional Information & Resources
Genetic Testing Information
Genetic Testing Registry: Cleidocranial dysostosis
Genetic and Rare Diseases Information Center
Patient Support and Advocacy Resources
Disease InfoSearch
Research Studies from ClinicalTrials.gov
Catalog of Genes and Diseases from OMIM
Scientific Articles on PubMed
Bruderer M, Richards RG, Alini M, Stoddart MJ. Role and regulation of RUNX2 in osteogenesis. Eur Cell Mater. 2014 Oct 23;28:269-86. doi: 10.22203/ecm.v028a19. Citation on PubMed
Bufalino A, Paranaiba LM, Gouvea AF, Gueiros LA, Martelli-Junior H, Junior JJ, Lopes MA, Graner E, De Almeida OP, Vargas PA, Coletta RD. Cleidocranial dysplasia: oral features and genetic analysis of 11 patients. Oral Dis. 2012 Mar;18(2):184-90. doi: 10.1111/j.1601-0825.2011.01862.x. Epub 2011 Oct 24. Citation on PubMed
Cohen MM Jr. Biology of RUNX2 and Cleidocranial Dysplasia. J Craniofac Surg. 2013 Jan;24(1):130-3. doi: 10.1097/SCS.0b013e3182636b7e. Citation on PubMed
D'Alessandro G, Tagariello T, Piana G. Cleidocranial dysplasia: etiology and stomatognathic and craniofacial abnormalities. Minerva Stomatol. 2010 Mar;59(3):117-27. English, Italian. Citation on PubMed
Dincsoy Bir F, Dinckan N, Guven Y, Bas F, Altunoglu U, Kuvvetli SS, Poyrazoglu S, Toksoy G, Kayserili H, Uyguner ZO. Cleidocranial dysplasia: Clinical, endocrinologic and molecular findings in 15 patients from 11 families. Eur J Med Genet. 2017 Mar;60(3):163-168. doi: 10.1016/j.ejmg.2016.12.007. Epub 2016 Dec 24. Citation on PubMed
Jaruga A, Hordyjewska E, Kandzierski G, Tylzanowski P. Cleidocranial dysplasia and RUNX2-clinical phenotype-genotype correlation. Clin Genet. 2016 Nov;90(5):393-402. doi: 10.1111/cge.12812. Epub 2016 Jun 30. Citation on PubMed
Machol K, Mendoza-Londono R, Lee B. Cleidocranial Dysplasia Spectrum Disorder. 2006 Jan 3 [updated 2017 Nov 16]. In: Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(R) [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2023. Available from http://www.ncbi.nlm.nih.gov/books/NBK1513/ Citation on PubMed
Roberts T, Stephen L, Beighton P. Cleidocranial dysplasia: a review of the dental, historical, and practical implications with an overview of the South African experience. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Jan;115(1):46-55. doi: 10.1016/j.oooo.2012.07.435. Epub 2012 Oct 24. Citation on PubMed
Ryoo HM, Wang XP. Control of tooth morphogenesis by Runx2. Crit Rev Eukaryot Gene Expr. 2006;16(2):143-54. doi: 10.1615/critreveukargeneexpr.v16.i2.30. Citation on PubMed
Stevenson DA, Carey JC, Byrne JL, Srisukhumbowornchai S, Feldkamp ML. Analysis of skeletal dysplasias in the Utah population. Am J Med Genet A. 2012 May;158A(5):1046-54. doi: 10.1002/ajmg.a.35327. Epub 2012 Mar 27. Citation on PubMed
Vimalraj S, Arumugam B, Miranda PJ, Selvamurugan N. Runx2: Structure, function, and phosphorylation in osteoblast differentiation. Int J Biol Macromol. 2015;78:202-8. doi: 10.1016/j.ijbiomac.2015.04.008. Epub 2015 Apr 13. Citation on PubMed
Wysokinski D, Pawlowska E, Blasiak J. RUNX2: A Master Bone Growth Regulator That May Be Involved in the DNA Damage Response. DNA Cell Biol. 2015 May;34(5):305-15. doi: 10.1089/dna.2014.2688. Epub 2015 Jan 2. Citation on PubMed
Related Health Topics
Understanding Genetics
What is the prognosis of a genetic condition?
How can gene variants affect health and development?
What does it mean if a disorder seems to run in my family?
What are the different ways a genetic condition can be inherited?
How are genetic conditions treated or managed?
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The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.


Achievement Guide for Butterfly Badges!
Butterfly 1 In Timberline, after seeing Dinkleman in the tire, go to Beth's truck.
Butterfly 2 Butterfly badges 2,3,4 are in the trash badge sequence in timberline.
Butterfly 5 Go across the street after meeting Elliot in Puni Mart Picnic, and turn right.
Butterfly 6 After Number 5, backtrack across the alley for badge 6.
Butterfly 7 In the Wake in the Wild, walk to the left of the log at the beginning.
Butterfly 8 You'll get this badge when you throw Elliot on the rock in Wake in the wild.
Butterfly 9 In Meet the Skunks, Meet the skunk, throw Elliot onto a ledge in the meadow.
Butterfly 10 In Hoof it, it's in the last section with the falling rocks.


Transform your living space into a tropical oasis with the pretty bunch of florals. A grand Bird of Paradise is all you need to give your space a bright and positive vibe. Printed on high-quality Oracal vinyl.


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By admin in Kenya April 2, 2020
Are you looking for quick cash for your personal or business use? here are the top 25 loan apps in Kenya offering friendly and low interest and competitive rates as well as flexible registrations online.
The loan apps in Kenya are assisting several Kenyans to get funds for their emergencies, and that is why many people are opting for it rather than making use of the traditional banks. These loan apps require little or no form of security to access them.
The following are the top 25 loan apps in Kenya;
Tala (Mkopo Rahisi)
This app was launched in 2014 as Mkopo Rahisi and later became Tala. It requires a Smartphone and a clean Mpesa Track record to get the loan. The loan is issued through your Mpesa account. Users can obtain between Ksh 500 to Ksh 50,000 loan at 15% interest rate. The loan is repaid weekly for 3 weeks using PayBill number 851900. Defaulters will be blocked from accessing future loans.
Timiza (Barclays)
This app is a product of Barclays Kenya. It is one of the newest apps in the loan market in Kenya. The applicant must own a mobile phone. Applicant should know that you do not require Barclay's account to make use of the app but it is recommended you increase savings in the app through the M-Pesa.
Branch Loan App
To access loan on the branch mobile app, you need to be registered with Mpesa and have an active Facebook account that has the same name as that on your National ID. It offers a minimum loan of Ksh 1000. The interest rate is dependent on the weekly instalment payment which decreases interest rate and increases credit score. So, link the app to a Facebook account and supply the necessary information, and verify your phone number via the link sent to your phone.
KCB M-Pesa
The users of the KCB M-Pesa app can access loans from between Ksh 50 – Ksh 1,000,000 at an interest rate of 1.16% monthly with 2.5% as a negotiation fee (this is one-off). This platform can be accessed through the Safaricom App or Mpesa menu on your Smartphone. Also, you could access it through the KCB App. Note that the applicant must have been active on Safaricom Mpesa for six months before application.
Zenka App
This is also among the new entrants into the loan business in Kenya. It is a reliable loan app in Kenya and has over a million downloads on the Google Play Store. The app offers loans between Ksh 500 – Ksh 30,000 with a repayment period of 61 days. The applicant should note that the initial loan is free, and it takes less than five minutes to get the money.
CBA Loop Loan App
See: CIBC Canada App Lets You Bank Securely on your Mobile
It was introduced in 2018 by the Commercial bank of Africa. The app also allows you to manage your finance from your Smartphone. Interestingly, this app not only offers loans, but also allows you to send money, invest, make payments, and make savings. To qualify, you must have been active on CBA Loop for three months and above.
Shika Loan App
Shika loan app stands out among the rest in Kenya. Also, it offers more than just giving out loans. This app is SMS based and acts as a platform for getting information on sports, entertainment, and politics. The Shika app serves as a platform where lenders find borrowers. The loans are targeted for start-up businesses like agriculture, asset acquisition, etc.
HF Whizz Loan App
This app allows you to borrow up to Ksh 50,000 and its operation is closely related to that of the Timiza App from Barclays. In addition to acquiring loans via the app, you could also send money and pay bills. It would, however, require you to have been active on the app for a while before qualifying for the loan.
Utunzi Credit App
It works through the M-Pesa platform just like similar loan apps. It is available for both business and personal with loans ranging from between Ksh 300 – Ksh 1,000,000 with a repayment period of between 91 days – 36 months. Users are charged 12% interest plus Ksh 400 annual subscription charges and 12% application fee.
Kopakash
This loan app offers credit between Ksh 1,000 – Ksh 50,000 with a repayment time between 91 days – 120 days. Once it is approved, the funds get credited into your bank account or your M-Pesa.
Okash Loan App
The Okash loan app has above a million downloads on the Google Play Store. It is designed to attend to people between the ages of 20 – 55 who earn a fixed income. It offers up to Ksh 500,000 based on the user's credit score. A requires 15 days to repay the loans. This is a product of Opera group (owner of the famous opera mini browser)
Berry Loan App
See: Don't Have a Bank Account in Kenya? Download KCB Mobile App
This is very unique with a low-cost interest rate and easy repayment plan. The first loan is usually not more than Ksh 500 which can be increased to Ksh 50,000. The app is user-friendly, a service fee of between 9 – 16% is charged and its repayment is via the app. The applicant needs to download the app, get verified, and boom, you have the loan.
iPesa Loan App
the iPesa loan is quite new in the loan industry in Kenya. It is an app that directly sends your funds into your M-Pesa. It offers between Ksh 500 – Ksh 50,000 with a repayment plan of between 91 days – 180 days. Interest rate is between 0% – 6% and service charge of between 5% – 10 %
Haraka Loan App
This is owned by a South African company called Getbucks. This app is also in operation in South Africa, Swaziland, Zimbabwe, Uganda, and Tanzania. The offers loan between Ksh 500 – Ksh 5,000. It is easy to qualify for loans and easy to repay.
FlashPesa
A product of Ambush Capital LTD; it is fast becoming popular in Kenya. It is designed to offer a loan of between Ksh 2,000 – Ksh 50,000 with over 100,000 downloads Google Play Store. Download the app and enjoy loans for your emergencies.
Saida App
To qualify for the loan, you must have an active Airtel Money and Mpesa account. The Saida app works by monitoring and reading your transaction and ascertain whether the loan can be repaid or not. It offers between Ksh 600 to Ksh 25,000 at 10% interest. It takes between 3 – 7 days for approval after download and other verifications.
OKOA Stima
This app is a product of Kenya Power in collaboration with Safaricom and was launched in 2015. It gives between Ksh 100 – Ksh 2000 and at 10% interest. Once approved, the money gets paid through the Mpesa within 7 days.
mKey Loan App
This app is designed by Finserve Africa and it is gaining rapid popularity in Kenya. In addition to obtaining loans via the app, users can also send money to mobile wallets like Equitel money, Mpesa, and Airtel money. Besides, you can get airtime for Equitel, Airtel, Telkom, or Safaricom.
See: What You Should Know About OKash Peer-to-Peer Lending App
Also, the app can be used to pay bills, buy goods and also serves as a news platform
Mshwari
This app offers loans through M-Pesa in collaboration with the Commercial Bank of Africa. It offers a minimum loan amount of Ksh 100 and the highest it can offer is yet to be fixed. The loan repayment is within 30 days with an interest rate of 7.5%. The loan application is done through Mpesa and processed within 5 minutes
Zidisha Loan App
It is available on the Google Play Store; it is a platform that connects lenders to borrowers. You must be a business owner, gainfully employed, be active on Facebook, a working Safaricom SIM card, national ID, and a good credit history to qualify for the loan.
Kopa Chapaa App
Kopa Chapaa app was designed by Faulu Kenya. To qualify for the loan, you need to be active on Airtel Money for at least six months. Users can get loans of between Ksh 500 – Ksh 100,000 with a short repayment period of 10 days
The Senti app is also new in the loan app business in Kenya. It is user-friendly and can offer a loan of up to Ksh 70,000. The app can be downloaded from Google Play Store or the Senti website. The app boasts of over 100,000 downloads.
Stawi Loan App
The loan app was launched by the Kenya Government in collaboration with CBA. It is made to target the Jua Kali sector especially the small-medium micro-enterprise. However, it has about 100,000 downloads via the Google Play Store.
Jazika
It gives a loan anywhere and at any time. To qualify for the loan, you need the app downloaded and M-Pesa line. The loan is settled on an instalment basis or one-off via a waybill number 687035.
Stawika Loan App
This app is gradually becoming popular in Kenya. After the download, the app checks through your M-Pesa usage and other factors to ascertain your eligibility. So, download the app, enter your PIN, confirm your loan limit and apply for the loan. The loan goes straight into your M-Pesa once it is approved.
Aside from these top 25 loan apps in Kenya, do you have suggestions on other mobile loan app offering competitive rates, feel free to share your comments?
Tags: Best mobile banking app in kenya, mobile banking app
This review covers everything you need to know about managing your personal and business banking account in New Zealand, credit...


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Wed, December 1, 2021 by ABC News
TriggerPhoto/iStock
HomePoliticsBiden declines comment on report Trump tested positive for COVID days before debate
(WASHINGTON) — President Joe Biden on Wednesday declined to comment on the claim former President Donald Trump's chief of staff Mark Meadows makes in an upcoming book, according to the Guardian, that Trump had a positive COVID-19 test three days before their first presidential debate.
Biden paused, and then responded with a smirk, "I don't think about the former president."
Later, White House press secretary Jen Psaki took a different tone — slamming Republicans and Trump allies she said had appeared to withhold the positive test result.
"What is not lost on us is that no one should be surprised that currently in Congress, as we're looking at the government staying open, you have supporters of the former president, supporters of the former president who withheld information, reportedly, about testing positive and appeared apparently at a debate, also held events at the White House, reportedly, with military veterans and military families," she said.
She said the White House did not know about Meadows' claim prior to the story breaking in The Guardian.
The nation's top infectious disease expert, Dr. Anthony Fauci, who notably was the target of Trump's ire for his messaging surrounding the virus, also said he "certainly was not aware of his test positivity or negativity" when ABC News Correspondent Karen Travers asked him about the revelation at the afternoon White House briefing.
"I'm not going to specifically talk about who put who at risk, but I would say, as I've said, not only from an individual but for everybody, that if you test positive, you should be quarantining yourself," he said.
The Guardian , which says it obtained a copy of Meadows' upcoming book, reported that Trump test positive on Sept. 26, sending shockwaves through the White House, before a second COVID-19 test came back negative, according to the Meadows account.
ABC News has not independently confirmed the book's contents.
According to the debate rules, each candidate was required "to test negative for the virus within seventy-two hours of the start time" of the Sept. 29 debate in Cleveland, Meadows recalls understanding in the book, according to The Guardian.
"Nothing was going to stop [Trump] from going out there," Meadows writes, according to the excerpt in The Guardian.
Trump's reportedly positive, then negative, in tests were taken on the same day of the now-infamous packed Rose Garden ceremony, described as a "superspreader event," in which Trump announced he would nominate now-Justice Amy Coney Barrett to the Supreme Court.
"Some people say you first got — you got an initial positive test even before the debate. Is that true or is that not true?" Karl asked Trump in a March 18 interview at Mar-a-Lago for his new book, "Betrayal: The Final Act of the Trump Show."
"No," Trump responded. "No, that's not true."
In a new statement on Wednesday, the former president called the reporting "fake news" — but did not flat out deny that he had tested positive before the debate.
"The story of me having COVID prior to, or during, the first debate is Fake News. In fact, a test revealed that I did not have COVID prior to the debate," he said.
Biden nominee would be 1st Muslim woman to serve as federal judge
Psaki, Harris argue Biden wasn't saying 2022 election results might not be legitimate
Supreme Court paves way for Trump White House document review by Jan. 6 committee
Biden holds rare solo news conference ahead of 1-year mark in office
Supreme Court Justices Sotomayor, Gorsuch dispute having COVID mask flap
Biden to hold rare solo news conference ahead of one-year mark in office


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Q: Handle exception in powershell I have a config file when you can add a list of performance counters, for example :
\Memory\Page Faults/sec
\Memory\Available Bytes
\ASP.NET Applications(*)\Requests in Application Queue

I have a powershell script, that parses the file and does a Get-Counter parameter where parameter is each counter in my config file. Everything works well, but I would like my script to be able to handle exception when an user add a bad counter, for example :
\Memory\Page Faults/sec
\Memory\Available Bytes
\ASP.NET Applications(*)\Requests in Application Queue
ddftrigjgigjij

With this, I get a red exception in my powershell console which I would like to replace with an appropiate message like "counter not found". I am beginning with powershell and I tried to use try\catch without success.
Thanks in advance for your help.

A: Add -ErrorAction Stop to Get-Counter, this will make try/catch work as you expect:
try{
    Get-Counter "bogus counter" -ErrorAction stop
}
catch {
    echo "counter not found"
}


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Marizyme Announces Approval for DuraGraft® in India
Latest Approval Joins a Growing List of Countries for Commercial Sales in 2021
Marizyme, Inc.
JUPITER, Fla., Jan. 14, 2021 /PRNewswire/ -- Marizyme, Inc. (OTCQB:MRZM), a publicly traded global biotechnology company developing products to reduce the burden of ischemia-reperfusion injury in tissue grafting, organ transplant, and other surgical indications, announced today that its flagship product DuraGraft® is now registered and licensed for import into India through Marizyme's distribution partner Regency Lifesciences.
India represents the latest market approval for DuraGraft, a CE-marked product that protects vascular grafts against ischemic injury and is the only product approved for graft protection and preservation during bypass and other vascular surgeries. Currently, DuraGraft is approved in the EU and seven additional countries with more world-wide approvals pending.
Dr. Neil Campbell, Marizyme, Inc. President and CEO, said, "We are excited to receive this approval in India and to be working with Regency Lifesciences to bring the healthcare professionals and patients of India this first in class product. India joins a growing list of countries that will form the basis of our commercial efforts in 2021 for DuraGraft."
Abel Alexander, Regency Lifesciences CEO, said, "This approval and licensure represents a significant step toward providing this novel treatment to the estimated 60,000 Coronary Artery Bypass Graft Surgeries per year."
When patients with heart disease undergo CABG surgery, free vein or arterial grafts harvested from the leg, arm or chest are frequently used to bypass occluded coronary arteries; about 90% of CABG surgeries use at least one free graft. In most cases, in the time between harvesting and bypass grafting, the free graft is stored in saline or autologous blood which do not protect the graft from ischemic injury thereby increasing the risk of ischemia-reperfusion injury and graft disease leading ultimately to graft failure, leading to post-CABG myocardial infarction and the need for repeat revascularization procedures.
DuraGraft is a CE-marked product that protects vascular grafts against ischemic injury and is the only product approved for graft protection and preservation during bypass and other vascular surgeries. DuraGraft protects graft tissue from the period of harvesting through anastomosis and is used during vascular surgery (including CABG) as a treatment to maintain the structural and functional integrity of isolated vascular grafts. The use of DuraGraft is associated with the reduction of post-CABG complications associated with graft disease and failure: Myocardial Infarction, Repeat Revascularization, and Major Adverse Cardiac Events (MACE).
Clinical studies in more than 3,000 patients support the long-term safety and efficacy of DuraGraft. The use of DuraGraft in CABG surgery is associated with statistically significant lower risks for clinical complications following CABG; 45% reduction in non-fatal myocardial infarction (MI) (p <.0001), 35% reduction in repeat revascularization (p=0.037), and 19% reduction of MACE (a composite of all major adverse cardiac events) (p=0.005) (Haime et al. 2018). DuraGraft is currently not for sale in the United States.
About Regency Lifesciences
Regency Lifesciences is a Leading Distributor of Healthcare Devices in India. Founded in the year 2001, by a group of highly experienced professionals with a strong background and cumulative experience of more than 37 years in the Indian Health care Industry, and are partnered with some of the world's best manufacturers of medical Devices and supply these products to all major hospitals across India. Regency Lifesciences offer the highest standards of service, making it a paramount objective to serve customers to the greatest of their ability.
Marizyme is an integrated life sciences company dedicated to the acquisition, development and commercialization of therapies that minimize mortality and costs in the acute care space. The company's flagship product, DuraGraft®, is an intra-operative vascular graft storage solution that inhibits endothelial damage and leads to improved clinical outcomes by reducing the incidence of complications associated with vein graft failure in bypass surgery. DuraGraft enhances coronary artery bypass grafting (CABG) surgical outcomes by significantly reducing major adverse cardiac events such as repeat revascularization and myocardial infarction. DuraGraft is approved for use in the EU and several Asian countries but is not yet approved for use in the U.S. Marizyme is also focused on the development and marketing of products based on its clinically tested and previously patented protease-based therapeutic Krillase® platform. Krillase is not approved for use in the U.S. For more information about Marizyme, visit www.marizyme.com.
Tiberend Strategic Advisors, Inc.
Maureen McEnroe, CFA/Miriam Miller
Ingrid Mezo
SOURCE Marizyme, Inc.
http://www.marizyme.com