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Healthy Childhood
High Quality and Safe Care
Professor Peter Gardner
I am a psychologist by background with particular interests in human factors and human interaction with organisational systems and technology. I have a long history of working on applied issues particularly with a health focus and more specifically in areas related to patient safety.
I was awarded my first degree, in Psychology, from the University of Sheffield in 1984, and I went on to gain a MSc in Computer Studies from Sheffield City Polytechnic, and a PhD in Cognitive Science from the University of Sheffield. Following this, I was privileged to work with Donald Broadbent and Dianne Berry at the Department of Experimental Psychology, University of Oxford before taking up a post to work with Toby Wall, Chris Clegg and Nik Chmiel at the MRC Social and Applied Psychology Unit in Sheffield (now the Institute of Work Psychology).
In 1995 I joined the University of Leeds as a lecturer, and became a Senior Lecturer in 2003. From August 2014 until January 2020, I was Head of the School of Psychology at the University of Leeds.
I joined the University of Bradford in February 2020. My role is to work collaboratively with colleagues in this University and in the Wolfson Centre for Applied Health Research (CAHR), in the area of Healthcare Quality and Safety. The Wolfson CAHR is a unique collaboration between the Universities of Leeds and Bradford and the Bradford Institute of Health Research.
Duckworth Lane,
Bradford BD9 6RJ
WCAHR.Info@bthft.nhs.uk
© 2023 The Wolfson Centre for Applied Health Research


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Q: How do the different kind of lamp dimmers work Hooked up the scope to a dimmer expecting to see how it altered the waveform, and didn't see it do much of any difference from all the way down to all the way up.
I bought an LED bulb and was told it needs a "special" CL dimmer.  How do the different kind of dimmers work, and how do I manage to see what they do with my scope?

A: Wikipedia has a nice article on phase angle control which is used for most house hold light bulb dimmers. They usually don't work for halogen, LED, TL. This is a typical case where a single image says more than a thousand words:

It works by chopping a (varying) part from the sine wave using a triac. The image shows a rectified wave, but the mechanism works equally well with an unrectified one, the latter being most common in household light bulb dimmers. The dimmer is connected in series with the lamp and therefore needs to see a minimum load (in the order of 10W) to work.
This is the classical dimmer. Not sure how halogen / LED / CFL differs from this, but I know from experience (with CFL) that an unmatched dimmer can make the lamp flash at a really annoying frequency.

redpajama_set_name: RedPajamaStackExchange


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The Writer's Welcome Kit
Home > Course Catalog > Writing as Curation
Writing as Curation
We'll discuss how describing and dramatizing encounters with works of visual art—real or imagined—can open up new possibilities for poetry and prose. In addition to considering student work, we'll look at examples of ekphrastic writing from The Iliad to the fiction of Javier Marías.
Due to COVID-19, all classes will take place online-either through Zoom or through Wet Ink, our asynchronous learning platform-through Winter quarter 2021.
All times are listed in Pacific Time.
Instructor: Ben Lerner
Class Type: 2 Sessions
Featured Writers, Fiction, Multigenre, Nonfiction, Poetry
Days of the Week: Friday, Saturday
Time: 10:00 am – 2:00 pm
Minimum Class Size: 8
Maximum Class Size: 16
$427.50 Member Price:
$475.00 General Price:
Class has begun, registration is closed.
Lerner is the author of the poetry collections Mean Free Path (2010) and Angle of Yaw (2006), which was a finalist for the National Book Award and the Northern California Book Award. His sonnet sequence, The Lichtenberg Figures (2004), won the Hayden Carruth Award, was chosen by Library Journal as one of the year's twelve best poetry books, and was a Lannan Literary Selection.
His poetry has also been included in the anthologies Best American Poetry, New Voices (2008), and 12×12: Conversations in Poetry and Poetics (2009). His novels include Leaving the Atocha Station (2011) and 10:04 (2014). The Hatred of Poetry, his monograph, was published by Farrar, Straus and Giroux.
Lerner has served as a Fulbright scholar in Madrid and as a Guggenheim fellow. In 2015 he was awarded a prestigious MacArthur fellowship. In 2002, Lerner cofounded, with Deb Klowden, No: a journal of the arts, and he has also served as the poetry editor for Critical Quarterly.
Born and raised in Topeka, Kansas, he earned a BA in political science and an MFA in creative writing from Brown University. He has taught at the University of Pittsburgh and California College of the Arts, and he currently teaches at Brooklyn College.
See current classes >

redpajama_set_name: RedPajamaCommonCrawl


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Implementing Steel Tariffs
Washington Insider --Thursday
US-China News Continues to Run Positive, Negative
Statements by President Donald Trump and other officials are continuing a pattern of seemingly getting one step forward and one or even two steps back in the process of reaching an agreement on trade issues between the two.
After Tuesday's news flow which saw reports that China was backing away from certain components sought by Washington in any trade deal and then word that top U.S. negotiators were headed to China next week, the pattern continued Wednesday.
President Donald Trump said as he left Washington that the U.S. would keep tariffs on Chinese goods for a "substantial period of time," potentially even after a deal is reached.
"We have to make sure that if we do the deal with China that China lives by the deal," Trump noted.
But he also sounded some positive notes, including that "top representatives" are headed to China next week for negotiations, a reference confirming the reports Tuesday that U.S. Trade Representative Robert Lighthizer and Treasury Secretary Steve Mnuchin would head to China for talks.
And even despite the warning on tariffs, Trump still labeled the talks as "coming along nicely."
Cruz Says EPA Will Keep Handing Out Small Refiner Waivers
EPA has given "explicit promises" to Sen. Ted Cruz, R-Texas, that the agency will keep granting small refiner waivers under the Renewable Fuel Standard (RFS) and will not retroactively reallocate those waived obligations, according to a report from Bloomberg.
Cruz said he extracted those pledges after working with other Republican senators to slow now-Administrator Andy Wheeler's nomination. Cruz said he and others extracted the pledge from Wheeler after warning that their votes were dependent on the administration continuing to lower the regulatory burden for oil refiners.
EPA said it would not "backtrack" on what Cruz labeled "vital regulatory relief" by not granting the small refiner waivers. "We are going to hold the EPA and the administrator to those commitments," Cruz said at the American Fuel and Petrochemical Manufacturers association meeting in San Antonio, Texas. "Those were public commitments that were necessary for his confirmation, and we fully expect him to follow through."
Washington Insider: Implementing Steel Tariffs
There are a great many questions about the administration's heavy reliance on tariffs as instruments of trade policy, but one that generally receives little notice is the equity of their application. Bloomberg is reporting this week that a number of firms are now raising questions about the role of the four largest US producers who have made a majority of the objections to other companies' requests for tariff relief, "sinking many importers' hopes of escaping the duties."
Nucor Corp., U.S. Steel Corp., AK Steel and TimkenSteel accounted for most of the objections submitted to the Commerce Department concerning steel tariff relief, Bloomberg says, and notes that US Steel and Nucor, respectively, prevailed in getting Commerce to reject tariff relief on 332 out of 333 and 515 out of 544 of decisions recently released, according to Rep. Jackie Walorski, R-Ind.
These data show that Commerce has denied more than 90% of applications where an objection was filed, Can Manufacturers Institute President Robert Budway said.
Walorski said she was concerned that Commerce may be evaluating "each request in a vacuum" without considering whether companies "can actually produce the cumulative total if they prevail in their objections."
Data on exclusion requests and objections are made public on line where they are posted for comment, although the postings are not always up to date, Commerce notes.
For their part, steel producers claimed that they filed only limited objections and did so "in cases where they could produce the steel for which tariff exemptions were sought." This suggests that producers are relying on the tariffs to hold down supplies, Christine McDaniel, senior research fellow at the Mercatus Center at the George Mason University in Virginia, told Bloomberg.
As of Dec. 20, 2018, US producers objected to exclusions on 145.2 million metric tons of steel — well above last year's domestic production of 81.6 million metric tons, she said.
"They would have to literally double or triple their production, which is unheard of," she said.
The American Iron and Steel Institute, the major steelmakers' trade group, said claims by some opponents of the process are "grossly misleading." Instead of focusing on the success of any particular request or objection, the focus should be on the impact that the cumulative requests could have. To date, the amount of steel from which US importers have requested relief far exceeds the volume that the entire US imported in 2017, according to the institute.
At the same time, delays in getting decisions on 23 exclusion requests filed in June are costly for Mid-Continent Nail Corp., which faces objections from Nucor, according to Adam Gordon of Bristol Group PLLC. While Nucor can produce the products in question, it cannot supply the quantities Mid-Continent needs, he said.
Gordon, who represents Mid-Continent, said extraordinary delays in processing exclusions are hurting downstream industries. One of the biggest things that would help speed up the process would be if steelmakers were more candid about their production limitations and choices, he said.
Independent Can Co. in Belchamp, Md., has about 24 requests still pending, President and Chief Executive Officer Rick Huether told Bloomberg. Domestic companies lack the capacity to service Independent Can's needs, he said. Independent Can, which needs an exclusion for tin plate, has spent some $160,000 just on filing the exclusions and paid about $800,000 in tariffs, he said.
"For a small company, this is very costly," he said.
A major problem with the system is lack of information on how Commerce makes a decision, trade attorney Bernd Janzen of Akin Gump said. His firm represents Volkswagen Group of America, which is waiting for decisions on requests where objections have been filed.
"How do they decide when the requester and the objector say different things?" he asked. Frustration with the delays and general opacity of the system will likely result in litigation, he said.
Most manufacturers of industrial products hate the tariffs and the current system and are quick to charge that it raises costs significantly for consumers across the United States. The charges that it adds uncertainty and is widely seen as inequitable are serious shortcomings that will be raised repeatedly as the administration's trade policies are reviewed in the process of considering approval for the new trade deals now being negotiated — a process producers should watch closely as it proceeds, Washington Insider believes.


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Home » Collection » Chapu, Henri-Michel-Antoine
Henri-Michel-Antoine Chapu
Artist Bibliography
Henri-Michel-Antoine Chapu, born in 1833, left his native village of Le Mée as an adolescent, when his parents moved to Paris as the concierges for the marquis de Vogüé. In 1848 he enrolled in the Petite Ecole to learn the tapestry profession. He changed professional course within the year and successfully competed for admission to the Ecole des Beaux-Arts in 1849. Chapu studied sculpture with James Pradier until the latter's death in 1852, then pursued sculpture and painting simultaneously with Francisque-Joseph Duret and Léon Cogniet (1794-1880). In 1855 he won the Prix de Rome in sculpture and moved to the Villa Medici late that year.
In contrast with the tumultuous career of his fellow pensionnaire, Jean-Baptiste Carpeaux, who became a lifelong friend, Chapu's career proceeded steadily towards success. The marble of his final Villa Medici envoi, Mercury Inventing the Caduceus (Musée d'Orsay, Paris), won a third-class prize in the Salon of 1863. Commissions for private and State projects began immediately upon his return to Paris in 1861. It was not until after 1870, however, that Chapu was in demand as a sculptor. His reputation skyrocketed with his greatest Salon successes, Joan of Arc at Domrémy, first shown in 1870 (plaster; Musée Henri Chapu, Le Mée), and La Jeunesse, the central allegory of a cenotaph for painter Henri Regnault (1843-1871) and other academy students killed in the Franco-Prussian War. The marble La Jeunesse won the gold medal for sculpture in the Salon of 1875 as well as subsequent accolades after the monument was inaugurated in 1876 at the Ecole des Beaux-Arts. Major commissions for the decoration of civil, commercial, and church architecture and fountains emerged soon after. Chapu's most acclaimed work in France and abroad, however, was his monumental funerary sculpture. The most famous are his initial projects with single-figure personifications for monumental stela (La Jeunesse, La Pensée, and L'Immortalité) and the gisants of high-ranking clergy and former royalty (notably that of the duchesse de Nemours, originally at Weybridge, Surrey [now Walker Art Gallery, Liverpool], and the duchesse d'Orléans at the Royal Chapel, Dreux). A replica of L'Immortalité, a nude male youth representing Jean Reynaud's belief in metempsychosis (astral migration of the soul after death), was placed on Chapu's tomb in the cemetery of Le Mée.
A member of the Académie des Beaux-Arts since 1880, he was elected its President in 1889. He had been a chevalier of the Légion d'Honneur since 1867, and was promoted to officer in 1872. Chapu's voluminous production was made possible by a large studio, with extensive personnel for the demanding technical work of his medium. Some were students who were more like medieval apprentices than observers. Contrary to the Ecole system, Chapu firmly believed in the artist's responsibility to master and practice sculpture as a craft; he practiced that credo himself. A superb craftsman, he remained directly involved in almost every phase of work.
Little is known about the extensive serial edition of Chapu's oeuvre. Commercial enterprises--notably Thiébaut and Barbedienne--produced bronzes and marbles of individual figures, as reduced variants, well into the twentieth century. Some may date from the last years of the artist's life. He died in 1891.
Chapu's artistic idiom was the iconic human figure; narrative was rare. In the realm of monumental art, his art negotiated an effective course between tradition and modernity for his generation. Whether historical or modern (Steam, 1889, Musée National du Grand Palais, Paris), his subjects beyond portraiture were elevated or sober, handled with a refinement that drew largely upon classical and Renaissance sources. It was an approach that avoided extremes: no violent gesture or expression; fastidious detail was absorbed within broad planes and clear outlines. Instead, Chapu's figures have a living, fluid grace, thanks to a mastery of anatomy, of the formal power of three-dimensional mass, and the nuances of surface handling. [This is the artist's biography published in the NGA Systematic Catalogue]
Fidière, Octave. Chapu. Sa Vie et son oeuvre. Paris, 1894.
Lami, Stanislas. Dictionnaire des sculpteurs de l'école française au dix-neuvième siècle. 4 vols. Paris, 1914-1921: 1(1914):328-342.
Centenaire Henri Chapu. Exh. cat. Musée Henri Chapu and Musée de Melun. Melun, 1991.
Butler, Ruth, and Suzanne Glover Lindsay, with Alison Luchs, Douglas Lewis, Cynthia J. Mills, and Jeffrey Weidman. European Sculpture of the Nineteenth Century. The Collections of the National Gallery of Art Systematic Catalogue. Washington, D.C., 2000: 87.


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Fluminense youngsters join FC Istres through Sambafoot partnership
Matheus Leandro will wear the number 9 shirt at FC Istres this season -
Sambafoot.com
Fluminense youngsters Matheus and Rafael Leandro Assis have joined Ligue 2 side FC Istres as part of the partnership that Sambafoot established between the two clubs last month.
The 20-year-old attackers will spend the 2013/14 season on loan in France as part of the deal and Matheus has already appeared in a friendly against Ligue 1 side Saint-Etienne.
Below is Sambafoot's interview with the young Brazilian…
Can you introduce yourself to the French public?
My name is Matheus. I started off playing Futsal in my city of Minas Gerais, before I joined Fluminense at the age of 12.
How did you arrive at Istres?
Sambafoot were in Brazil to observe me and set up a partnership between Fluminense and the French club. They liked my work and different qualities so I did a three-week trial in April with Istres.
What do you think about France?
This is a good country, very different from Brazil. I'm happy here, very happy. There is a good future for me here.
And what do you think of French football?
It is more physical, technical and tactical. Brazilian football gives more freedom, but tactically it is not as demanding. I think I will fit in well in French football.
How are you adapting?
The language is difficult, but the club has welcomed me very well. The food is very good here too. I am making an effort to adapt to the tactics as it is not as sharp in Brazil.
What is the most difficult for a Brazilian who arrived in France?
It is communication and distance from family in Brazil.
Do you personally know any Brazilians playing in France?
I know Lucas Mendes, who plays for Marseille, and he is a great person, very humble. We have already been able to eat together at a restaurant. Brandão, I have not talked to him but I guess he is a pretty cool person.
What do you think of the Istres team?
This is a close-knit team. It does not have many stars but it is a strong team. I will fight for this team to finish in the top five of Ligue 2.
What are your main characteristics?
I am a centre-forward, like Ronaldo. I'm pretty physical, not slow or fast for a player of my size. I'm a striker and although I have yet to score here, there will be goals this season.
How do you see this partnership between Istres and Fluminense?
Fluminense has many players and tries many partnerships, but some do not work. But with Istres, all went well. Fluminense believe Istres is a serious club and it's good for both parties.
Who is your favorite player?
My favorite former player is Ronaldo, and now I like Cristiano Ronaldo.
You recently played against Saint-Etienne in a friendly? Was it a good experience?
It was a very good experience, it's a dream to be able to play against a first division team. Playing against Brandão was also a great experience. I hope to play a lot this season and next season in Ligue 1.
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Hey guys, I am in a struggle right now and need your help.
What in the world am I doing wrong ?
How do I start growing ?
Are you following related pages? Following the people that like those pages? Interacting with the people that like pages that are similar to yours?
It sounds like you're under the assumption that people will see your profile, follow you and interact with you.
Yes, I am following around 1,600 people and 240 are following me (back).
I follow the followers of related pages.
But once you stop following people, they just stop interacting with you and you can't grow and I feel like the only way you could grow is to follow / unfollow (due to limit) people.
Following isn't the only way to interact with people on Instagram. Like and comment on photos of your followers and the people who follow similar pages.
4. Use Garry vee's 1.80 $ method ( google it ) - it's about interaction, not money.
5. You can post other people's content and give them a credit in the description, or tag them.
6. Like other peoples comments.
7. Ask questions on your pictures ( with subtilities) and try to post a vid form time to time as they are more likely to go viral.
I think, it was helpful - I can recommend you two cheap tools for hashtag research and IG automatization - It's Jarvee and Ashatory.
To go more into depth on Gary Vee's $1.80 strategy, growing on Instagram organically these days can only happen from constant interaction in your niche (or a shoutout from a big page). By leaving your 2 cents on 90 top posts in your niche, you will soon get recognised and people will start following. However the only problem is that it is a bit tedious, however if you stick with for 30 days, the results are pretty worth it.
Related to the Jarvee app, I am planning to use it since I tried the trial period and I like it, but still find it kind of confusing and I do not know how to use it safely.
I would like you to be my referral when I buy the monthly subscription.
Please send me a referral link.
Also, do I have any other costs than the usual monthly subscription if you are my referral or you use the benefits as a referral.
Thank you for the tips and hear from you soon.
How many people are you following daily? A number I could advise is 300 per day per account. Automation and multiple accounts may also improve results. However, it can get expensive.
Are you maximizing views on your posts by adding the most popular hashtags for your niche?
Yes, I do enter hashtags (between 5-9 per post) and with the followers I have (240) I have maybe 25-60 likes per post.
I know that these likes are not gained from my followers but anyway the likes don't convert to followers.
Well done buddy, profile-wise. All checks covered.
You are doing nothing wrong. But you are seeing no growth because you neglect a certain activity that virtually all struggling IGers neglect; going off-site aka off-profile.
Follow those 3 steps generously for the next month. Be authentic. Be genuine.
All growth with your IG account should skyrocket because you'll generate interest, by being interested in others. Easiest way to grow your IG account quickly, by far.
It can be exhausting operating a business account on Instagram. To get the attention you need to stand out from your competitors, you need to receive a lot of engagement. That means spending countless hours interacting with others to convince them to follow you.
Some people just don't have the time to do this, especially while running a company. Fortunately, there are services out there that can do it for you. In fact, they can do it quicker and more efficiently than any one person could.
I really believed that it can be done otherwise, but the time you will spend doing that manually is time wasted, at least in these early stages of growing.
The risk of being blocked is surely there, but I continue to be convinced that it is probably worth it.
Interaction is a big part of gaining and retaining followers. It's not just about following. You have to like and comment back to them, tag them in posts, etc.
A graphic designer I hired long ago suggested that I try out those automated Instagram apps like follow liker. I would use them with caution, however. Instagram doesn't exactly like it when we use bots to gain followers.
On a more personal note, I prefer getting followers organically than through paid software, but to each his own. It's harder, but it makes the follower count mean more than just a number to me.
Interact more with people: follow, love, and give constructive comments.
I suggest you keep up the high resolution content, have a good quality photos, use appropriate hashtags, communicate with your audience and follow some of them.
Have you tried video content? have you come in front of the people? have you added so much value to your readers? Have you replied to every comment?
Have you commented on other people's Instagram in your niche? Have you tried paid post? Have you used other platforms to create awarness? are you meeting with people in your niche?
Although I am sure there are people on this forum that have much more experience with Instagram than I, I want to share some of the things that worked for me pretty reliably.
Keep in mind that Instagram is much more than just a picture that you are posting. Words in descriptions are very important as well because they are used by the Instagram algorithm and ranked accordingly (yes, Instagram is a search engine, shocker). Therefore, you need to use a lot of text. Try writing two to three paragraphs to each picture and optimize the text for the keywords you want to rank for. More text means that you will take more space on somebody's screen, increasing the chances that somebody will notice you and read what you wrote.
Instagram is centering on a storytelling. Include a short story about the image that catches people's attention, inspire them, help them realize their potential. Try to include emotions in your text because emotions appeal to more than just reason of a person.
Make sure every image is very subtly branded with your handle (meaning your profile name, such as @Joe). Do not overdo it though, you only need something small, that will not take away from the actual image. Branding like that will create an association between the topic and brand. A lot of people think that you improve brand awareness when people click and interact with your content, but what they fail to take advantage of is all the people that scroll past your images. When enough people would see your name together with images about food, they will start associating you with it. Eventually, some of those people will start clicking on your images over other people in the food industry because of the familiarity they developed over time.
Best handle to have for such branding is a short and memorable one, so that people would remember it easily. So if you have a chance to change it for better one, I recommend you do it.
Regarding following others, I found that tagging other people to your posts work great. Make sure those accounts have similar following and story. Work on enticing them to like or comment on your images. Once they do that, it shows up on their profile for their followers to see, so you'll get a nice inflow of traffic over to your profile from that.
Regarding hashtags, Even though Instagram allows up to 30 hashtags (I think), I wouldn't recommend going over 10-15 hashtags at most. I would stay around 10 to be safe. Spend time at coming up with a variety of hashtags, in o order to avoid Instagram labeling your post as a scam. Go to Displaypurpose.com and use their hashtags generator if you can't come up with any.
Share other user's content. When you find something interesting that other people in your topic are posting, share their stuff while giving them the credit for work. Moreover, add something valuable to it by commenting. This way you are building valuable relationships that will compound over time.
Last but not least, experiment with Instagram Ads. Even though this is a paid option, there is no harm in trying it out, especially if you have a post or two that are receiving a lot of action from organic traffic. Blasting them to new people in the specific audience can gain you a lot of new followers.
Oh, one more thing before I end thing behemoth of a reply. If you overuse your hashtags, your Instagram post can actually receive what call a silent penalty. Just like with SEO and over-optimization of the website, over-optimizing your post may result in your post losing its ranking or dropping off of the list altogether. The worst thing is that you don't receive any notification when this happens and often only see a drop in activity (fewer likes/comments). With new posts, you may think the post is just not interesting to your audience, when in fact it could've been a killer if not for the penalty. I found that taking off all the hashtags from the post for few days usually removes the penalty.
That is all I have to say. I hope this will help you grow your audience at least a little bit. Have fun and be patient.
1) Get creative with your hashtags. Be funny, ironic, or outrageous - but never boring!
2) Promote your dedicated hashtag on your other social profiles, on your website, and your email blast.
3) Use your bio link to drive traffic to your newest or most popular content.
1. You may consider the follow/unfollow method but please be careful of its restrictions and all.
And if you are using a bot, please be even more careful.
This is one of the fastest way to build a following.
You got that right. You need to be posting videos, especially viral videos. Heck, it doesnt even have to be your own content. Reposting is one of the best ways to get traffic to your Instagram account.
But in the end of the day, what you want is traffic to your bio link where you build your list (I hope), so why not consider other means, such as a solo ads or something instead? Unless you have a large following, it is going to be very difficult to monetize it.
Don't use popular hashtags, use specific ones - related to the content you're posting. Also, you can use tools for boosting your post engagement, such as Fuelgram. This tool brings you numerous likes and comments from real profiles belonging to your niche, puts you on top of the explore feed, and after some time you'll get more likes and followers organically.
If your focusing on "Instagram". You are also publishing your instagram to keep related other social media platform like facebook, twitter, tumblr, reddit and more.
I hope that, you will be get better results for this.
It may be laborious running a business account on Instagram. To get the eye you want to face out out of your competition, you need to acquire a whole lot of engagement. That means spending infinite hours interacting with others to persuade them to follow you.
Some human beings simply don't have the time to do this, particularly while running a corporation. Fortunately, there are offerings obtainable which could do it for you. In fact, they can do it quicker and more effectively than anyone person ought to.
You are also publishing your instagram to keep related other social media platform like facebook, twitter, tumblr, reddit and more.
Well, a lot has been said but from what I've observed your following greatly outweighs your followers and that seems like a characteristic of a bot-operated account.
Besides posting good content regularly, you need to be calculative of your hashtags. Advisedly, as a beginner, you should be targeting hashtag between 25k to 200k.
Also, though another commenter advised against using more hashtags but for me, I always try to use a minimum of 25 hashtags though I mix them always and I have had a steady rate of engagement.
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The best would be if you get the early engagement from big accounts from your niche. The good news is you can easily get that.
You can get the early engagement through engagement groups. Engagement Groups are groups of Instagram accounts. On Telegram, for example, is a group of 600+ people. Most of them are from the motivational quotes/success quotes niche.
You can join this group and big accounts with 100.000+ followers will like and comment on your posts. This is how your posts go viral and get thousands of impressions. It´s that simple.
Let me explain how this engagement group works, how you can get into it and all that.
your username. You then can decide whether you want to join the round or not. The bot says that at 8:30 am, 11:30 am, 2:30 pm... (every 3 hours).
At 9am est, 12 am 3 pm, 6 pm.... (every 3 hours) the bot then say that the round started. Once the bot says round started you go to Instagram and upload your post.
He creates a list of all usernames that have been dropped and messages you the list. You then have to take that list, copy it and message the list to yourself on Instagram. Then you have to click on each username and like and comment on their last post.
Everyone from the list will do that with your last post too. This is how you get early engagement.
Do you engage with the community? Take time to like and comment on others' posts every day. You can also grow with Fuelgram, which is a niche-based powerlike service with a huge base of real account. It helped me a lot with my growing.
INTERACTION is key here.. sure follow and like.. BUT LEAVE A COMMENT. your little acct name that shows up.. THAT is a link to your feed.. follows and likes are specific to ONE person.. COMMENTS are open to anyone that reads them.
REMEMBER It is called SOCIAL media.. its not LIKE media, or FOLLOW media.
And this whole you need a bot thing.. For the love of... something. DONT do it - there simply is no reason to.. and WHY? risk your account? If you cant go out and comment on a few feeds a day, everyday.. then there is something else wwrong.
I could seriously start up an account TODAY.. put up 2 pieces of content and have likes and followers in HOURS.. Add more content and more commenting.. and in DAYS it will be hundreds.. Its simply NOT THAT HARD. Visit a feed and type in a comment, and like the thing.
Are you using #f4f #l4l and other hashtags alike??
maybe some special pr or marketing specialist should help You?
Use tags and hashtags and leave comments on relevant pages and try to interact with them.
Hmm, I think you need more interactions. Remember that Digital marketing is just like traditional marketing, except it happens on a different space. What I am trying to say is that you should try to connect with other influencers. Commenting or liking an influencer who gathered a lot of followers won't hurt you. Sending DM to them or even collaborating will surely give you followers and put legitimacy to your whole account.
what are you doing wrong? your not doing the work... You have a phone right? TAKE YOUR OWN DANG pics and EARN followers... why would I follow a account that is posting pictures I have already seen? COME ON MAN!
And lets REALLY get to the point.. what do followers do for you? why focus on that.. are you trying to convert the traffic to something? or are you just in a vain quest to show your buddies you are someone with 1000 followers?
Seriously think about what you are doing... you are stealing other peoples images to get "respect" from people you probably don't even know... Im going to be super blunt at this point.. you are being FAKE.
Best of luck man.. I truly wish you the best!
Try to find some engagement groups on telegram.
Thats how you can grow fast.
Collaborations worked for me, keep it niche specific. You can also consider influencer marketing. If you have a service or products to offer then you can definitely offer that as a trade for a shoutout from them.
Use comment on website for relative page and build up your relationship.
3. Becoming well known, famous and perceived as an Instagram influencer.
But how can you attain more followers on Instagram?
There are a few ways you can go about doing this, however, the easiest method to attract real followers to your Instagram profile is to simply invest in an Instagram bot management tool.
A bot (AKA web robot) for those who may have not heard of this before is basically just another word for software that runs automated tasks over the internet.
Instato works in three basic steps. First, it works to generate activity. Secondly, it schedules and automates your content, which then leads to more and more followers.
Another way to grow Instagram followers is to use interesting hashtags and to avoid the overuse of hashtags. Also taking good quality photos can have an impact on the number of Instagram users that could be engaged in your posts and content.
First, you have to follow the Instagram followers with your relevant niche, You also have the same type of follower's following you back on your Instagram. You have to post daily content on your Instagram page. You have to follow more people relevant to your niche on a daily basis. This may good for your Instagram traffic and you have to create multi-account or automation for getting more traffic.
Expand your reach to grow.
Post at right time is more important.
You need to use those popular related hashtags to engage with people in the same niche. Comment, like, and add value to their posts. Use all the tools Instagram gives you such as IG TV, and stories to engage your audience. The first 5-10k followers may require some work but after that it will start to pick up.
Here is Some Step You Can Use and You Will Definitely Get Lot of Likes on Instagram.
1. Be Strategic with Your #Hashtags.
3. Explore the Full range of Instagram Video Formats.
4. Post Images that People Relate to.
5. Use Instagram Video Subtitles and Closed Captions.
6. Post them at the Right Time.
7. Reshare on Other Networks.
Thank you for the comments here, this will be a great topic and help others too like me.
recently i open my instagram account travel related. i post always related photos, related hashtags and descriptionbut don't growing my account.
Here are Some Step That's Help to Growing Your Account. You Can Use and You Will Definitely Get Lot of Likes, Followers & Engagement on Instagram.
2. Connect Your Instagram Account to Facebook.
5. Make Your Filter Schemes Part of Your Branding.
6. Explore the Full Range of Instagram Video Formats.
Of course, we need to quickly touch base on what you shouldn't do when trying to grow your account.
First, don't get too hung up on your numbers!
It's a slow game, and if you are checking your follower count every couple hours, you'll drive yourself mad seeing the number go up and down.
Secondly, set goals that are realistic.
Don't plan on reaching 10,000 followers in three months if you are just starting out.
Is it possible to reach that many followers in such a short amount of time?
I guess anything is possible, but to be honest, it's not the norm.
It's ok to grow slow. I personally don't know any bloggers who haven't spent at least a couple years growing their accounts to sizeable followings. So, less focus on the numbers!
A follow train is when you drop a link to your Instagram account somewhere, and everyone else who has left their link has to follow everyone.
These result in a whole bunch of random followers who likely don't care about your content.
In my Facebook group, Creative Girl Bosses and Bloggers I do a variation on this where I only require participants to follow five other accounts of their liking.
This ensures that people are only following accounts they like, so if you'd like to participate in a follow train, try to find ones like that. You don't get as many followers, but the followers you get will actually be engaging with your content.
Giveaways can be a great way to get more followers, but you can also end up with lots of non-targeted followers if the item you are giving away is too broad and appeals to too many people.
You might end up with a spike in new followers, but they probably won't interact with your content which will really hurt your account in the longrun.
If your followers aren't interacting with your content, the algorithm will stop showing your posts to as many people.
You should also read my story on how I ended up losing 3,000 followers after a poorly-planned giveaway.
If you'd like to grow your Instagram account in 2019, remember that creating a community and engaging is going to be a huge factor in your success.
On top of taking the time to genuinely engage with others, you should also make sure your photos are appealing.
Hash Tags is very important facts for instagram followers. Instagram allowed 30 hash tags. Take to each post maximum tags with good content. Follow targeted audience and comment and like their post. And finally staying to active every day.
Here are Some Step You Can Use and You Will Definitely Growing Your Followers & Likes on Instagram.
2. Creating Content Your Audience Will Love And Interact With.
3. Use Popular and Trending Hashtags.
4. Try Videos, Live Videos, and Stories.
8. Comment with a Question.


text:
Mariana Alcoforado () a fost prozatoare portugheză și călugăriță în cadrul mănăstirii Convento de Nossa Senhora da Conceição din Beja.

Opera
I se atribuie Scrisori portugheze traduse în franceză ("Lettres portugaises traduites en français"), publicată în 1669 de către librarul parizian Claude Barbin.
Scrierea este considerată o capodoperă a literaturii de dragoste, iar autoarea ca precursoare a romanului sentimental și epistolar.

Bibliografie
 Danțiș, Gabriela - Scriitori străini, Editura Științifică și Enciclopedică București, 1981

Legături externe
  Biografie la Encyclopedia Britannica
  Biografie la Projecto Vercial
  Biografie la Biografie

Nașteri în 1640
Decese în 1723
Scriitori portughezi
Portughezi din secolul al XVII-lea
Portughezi din secolul al XVIII-lea
Scriitoare din secolul al XVII-lea
Scriitoare din secolul al XVIII-lea
Femei din Portugalia

redpajama_set_name: RedPajamaWikipedia


text:
Elegant. Stunning. Luxurious.
All of the Above + -
The A.S.A Show
Spring 2019 Couture: Balmain
Since taking over the creative direction of Balmain nearly nine years ago, Olivier Rousteing has proven that the world is his oyster. To cover what he has achieved—the global brand growth, design identity, inclusive messaging, and far-reaching popularity—would run the length of this review. Thus, the revival of the maison's haute couture atelier must have been his pearl; a rare and valuable manifestation of beauty, its iridescent nacre akin to layers of workmanship.
And so it's not for nothing that pearls played a central part in his first couture collection. Right from the start, they appeared as giant Balmain-emblazoned orbs encircling wrists and carried in hand; they were the obvious reference for bulbous skirts molded in leather; and they were applied in bounteous quantities to lattices of ornamentation, from suits to jeans. They were the only reasonable explanation for the models' filmy white makeup.
In a preview of the collection, which took place next to the busy in-house atelier, Rousteing explained that he sees his haute couture as bridging the Balmain of the past with today. "Of course, the house is known for being edgy and sexy and glamorous. Here, it's all about bringing back Balmain to the elegance of la France," he said, adding that the maison's archive proved essential. "Everything you see will give the sense that it's taken from the ideas of Mr. Balmain." This much is clear; the tiers upon tiers of frothy tulle, theatrically pleated fan shapes, and figure-swallowing bows looked nothing like Rousteing as we know and love him.
By adding the new Balmain logo as a graffiti treatment to a superhero peplum or encrusting denim in embellishment, Rousteing said he was answering the question: What is couture in 2019? That his answer missed the mark might be owing to a few understandable considerations. The statement pieces in his ready-to-wear, as well as last year's 44 François Premier red carpet collection, already approximated couture, leaving him with little creative oxygen. Haute couture also carries such historic, weighty precedent that growing pains will be inevitable. Finally, Rousteing has been in awe of fashion since a very young age, when he marveled over the creations of Yves Saint Laurent for Catherine Deneuve and those of Karl Lagerfeld at Chanel. Maybe these exaggerated, reimagined '80s volumes and ultra-pretty pastels were the fulfillment of a long-held fantasy. "Let's be dreamy and inspirational," he enthused during the visit.
There was, alas, nothing much dreamy about the venue—the forthcoming flagship on Rue Saint-Honoré, still in a state of incompletion. This can be forgiven and soon even forgotten. The part that lingers is that, for someone who has formed such a solid connection through his #BalmainArmy, who just launched an app meant to democratize the Balmain experience, and who has ensured that you can't go four blocks in Paris without being made aware of Balmain, the collection went backward not forward. On the plus side, the line is so exclusive that it won't change the course of Balmain's history—or fashion's.
So for now, one can only ask, Who is the Balmain couture woman? Cue Rousteing's reply, which can be interpreted as you wish: "It's an interesting question because we don't know."
Book Signing with John Tschirch
Travel Destination: Newport, RI Aardrark Antiques
Angelina's Confirmation
Angelina's 2nd Degree: Graphic Design
Travel Destination:The Miami Beach Edition Hotel
About Angelina
CDA Press
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text:
BioEdge: Transhumanism. Child euthanasia debate in Netherlands
Although it has been called the world's most dangerous idea, transhumanism probably provokes more ridicule than fear. Uploading one's brain onto the internet or talk of thousand-year life spans seems to defy common sense.
Nonetheless, my theory is that transhumanism is the logical outcome of a lot of contemporary bioethical theory. So developments in transhumanism are worth paying attention to.
The biggest story at the moment is the quixotic campaign of the head of the Transhumanist Party, Zoltan Istvan, for president of the United States. He is a philosophy and religious studies graduate of Columbia University and has worked as a journalist for the National Geographic Channel.
Mr Istvan has been running a blog on the Huffington Post for a while about his campaign which aims to make the platform of his party more plausible. In the latest post he defines transhumanism as "the radical field of science that aims to turn humans into, for lack of a better word, gods". So while transhumanism is resolutely atheistic, it has religious aspirations.
And unlike Richard Dawkins and other militant atheists, Istvan argues that our responsibility is to transcend evolution. He writes: "the human body is a mediocre vessel for our actual possibilities in this material universe. Our biology severely limits us. As a species we are far from finished and therefore unacceptable… Biology is for beasts, not future transhumanists."
It's a curious development. While many prominent scientific thinkers want to abolish God and treat man as one beast amongst many, transhumanists want to abolish evolution and recreate God (or gods).
This week in BioEdge
Dutch paediatricians seek child euthanasia
by Michael Cook | May 01, 2016
Government to fund study
Shakespeare and bioethics
by Xavier Symons | Apr 30, 2016
What did Will have to say about medicine and health?
UK judge sceptical of circumcision for boys
by Michael Cook | Apr 30, 2016
Let them choose for themselves
Indigenous Canadians fear impending euthanasia law
Suicide crisis in remote towns highlights need for caution
A pro-life case for altering the genome
There are risks, but it could save lives
Kuwait to establish national DNA record
In a world first, the State of Kuwait will require all citizens and visitors to provide DNA samples to government authorities.
Sale of complementary medicines unethical: Australian doctors
Criticism is mounting in Australia about the sale of low-evidence complementary medicines in pharmacies.
Artificial concerns?
This week Nature published a strident editorial defending 'legitimate concerns' about contemporary AI research.
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Email: michael@bioedge.org
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Hearing Aids May Help Keep Seniors' Minds Sharp: MedlinePlus
Hearing Aids May Help Keep Seniors' Minds Sharp
Ability to stay engaged in conversation could help ward off dementia, study suggests
By Robert Preidt
WEDNESDAY, April 27, 2016 (HealthDay News) -- A hearing aid may do more than help you hear better: New research suggests that the devices might also help prevent mental decline in elderly people with hearing loss.
"We know that hearing aids can keep older adults with hearing loss more socially engaged by providing an important bridge to the outside world," Dr. Anil Lalwani, a professor of otolaryngology/head and neck surgery at Columbia University Medical Center in New York City, said in a center news release.
"In this study, we wanted to determine if they could also slow the effects of aging on cognitive function," he added.
The study included 100 adults, aged 80 to 99, with hearing loss. The 34 who regularly used a hearing aid had much better scores on tests of mental function than those who didn't use a hearing aid.
The researchers also found that mental function was directly linked to hearing ability in those who didn't use a hearing aid.
The study was published online April 25 in the American Journal of Geriatric Psychiatry.
"Our study suggests that using a hearing aid may offer a simple, yet important, way to prevent or slow the development of dementia by keeping adults with hearing loss engaged in conversation and communication," Lalwani said.
More than half of people older than 75 have hearing loss. But, fewer than 15 percent of those with hearing loss use a hearing aid, the researchers said.
Previous research has shown that hearing-impaired elderly people are at increased risk for fall- and accident-related death, social isolation and dementia, compared to those without hearing loss.
Previous studies have also found that hearing aid use can improve hearing loss-related social, functional and emotional problems, the researchers said.
SOURCE: Columbia University Medical Center, news release, April 25, 2016
HealthDay
Copyright (c) 2016 HealthDay. All rights reserved.
News stories are provided by HealthDay and do not reflect the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, the U.S. Department of Health and Human Services, or federal policy.
More Health News on:
Gotta Minute? Get a Good Workout: MedlinePlus
Gotta Minute? Get a Good Workout
Study found 60 seconds of intense exercise as effective as 45 minutes of moderate exertion
WEDNESDAY, April 27, 2016 (HealthDay News) -- Couch potatoes, there are no more excuses.
New research from Canada contends that just one minute of high-intensity exercise can boost your health as much as 45 minutes of a moderate workout. That means you can't claim that you don't have enough time to get in shape.
"Most people cite 'lack of time' as the main reason for not being active," said study author Martin Gibala, a professor of kinesiology at McMaster University in Hamilton, Ontario. "Our study shows that an interval-based [intense] approach can be more efficient -- you can get health and fitness benefits comparable to the traditional approach, in less time."
The study included 27 inactive men who were randomly assigned to do either intense or moderate workouts three times a week for 12 weeks, or to a control group that did not exercise.
The intense exercise was so-called sprint interval training, which involved three 20-second "all out" sprints on exercise bikes. It also included a two-minute warmup, a three-minute cool-down, and two minutes of easy cycling for recovery between the intense sprints. Total time: 10 minutes per workout.
The men in the moderate workout group did 45 minutes of continuous cycling at a moderate pace, plus the same warmup and cool-down as those in the sprint interval group.
After 12 weeks, both exercise groups had similar measures of heart/lung fitness and insulin sensitivity, a measure of how the body regulates blood sugar.
Interval-based training "is a very time-efficient workout strategy. Brief bursts of intense exercise are remarkably effective," Gibala said in a university news release.
"The basic principles apply to many forms of exercise. Climbing a few flights of stairs on your lunch hour can provide a quick and effective workout. The health benefits are significant," he added.
The study findings were published online April 27 in the journal PLoS One
SOURCE: McMaster University, news release, April 27, 2016
Exercise and Physical Fitness
Psoriasis Tied to Obesity, Type 2 Diabetes: MedlinePlus
Psoriasis Tied to Obesity, Type 2 Diabetes
A genetic link is one theory for the possible association, researchers say
WEDNESDAY, April 27, 2016 (HealthDay News) -- The chronic skin disease psoriasis may be linked to excess weight and type 2 diabetes, results of a new study suggest.
Danish researchers found that people with type 2 diabetes had more than 50 percent greater odds of having psoriasis compared to people without diabetes.
The study also found that the rate of psoriasis went up with increasing weight. For example, obese people with a body mass index (BMI) over 35 had almost double the odds of psoriasis than normal weight people did. BMI is a body fat measurement based on height and weight. A BMI of 30 or over is considered obese.
Exactly how these conditions might be connected isn't clear, but the study authors suggested that genetics, smoking, drinking alcohol, or inflammation might play a role.
"Psoriasis is a complex disorder," said lead researcher Dr. Ann Sophie Lonnberg, of the University of Copenhagen. "The genetic background for the disease and its many comorbidities [co-existing conditions] have not yet been fully uncovered," she said.
This study can't prove that psoriasis causes type 2 diabetes or obesity or vice versa, Lonnberg added. However, the study suggests the association between psoriasis and obesity could partly be tied to a common genetic cause, she explained.
"The reason psoriasis and obesity are associated is not only due to a common lifestyle, but they are also associated due to common genes," Lonnberg said. "It is important to treat psoriasis and obesity and diabetes, since they are risk factors for heart disease and could have serious effects on overall health."
For the study, Lonnberg and her colleagues collected data on nearly 34,000 twins, aged 20 to 71. Just over 4 percent had psoriasis, slightly more than 1 percent had type 2 diabetes and over 6 percent were obese, the findings showed.
Among the nearly 460 individuals with type 2 diabetes, about 8 percent also had psoriasis. Among people without type 2 diabetes, just 4 percent had psoriasis, the investigators found.
People with psoriasis tended to weigh more than those without the skin condition, the researchers said. The risk for obesity was also greater among those with psoriasis -- 11 percent of people with psoriasis were obese, but only 8 percent of non-obese study participants had psoriasis, the findings showed.
The researchers also looked at 720 twin pairs in which one twin had psoriasis and the other didn't. The twins with psoriasis weighed more than the twins without psoriasis, and were also more likely to be obese, the study found. The prevalence of type 2 diabetes, however, was the same in twins with and without psoriasis, according to the report.
The study was published in the April 27 online edition of the journal JAMA Dermatology.
"Psoriasis is not just a disease of the skin -- patients and health care professionals need to be aware of systemic health issues associated with psoriasis," said Dr. Joel Gelfand. He's an associate professor of dermatology at the University of Pennsylvania Perelman School of Medicine in Philadelphia, and author of an accompanying journal editorial.
Other studies have suggested that people with psoriasis are more likely to develop type 2 diabetes even if they don't have major risk factors for the blood sugar disease, and that this risk increases with the severity of the psoriasis, Gelfand said.
"Some of this risk may be due to shared genetics between psoriasis and diabetes. It is also thought that chronic inflammation in psoriasis may predispose patients to diabetes," Gelfand explained.
He suggested that people with psoriasis -- particularly those aged 40 to 70 with more extensive skin disease -- should receive medical screenings for diabetes.
"Patients with psoriasis who are overweight or obese may lower their risk of diabetes while making the skin disease less active if they are able to achieve and maintain a more healthy body weight," Gelfand said.
Another doctor thinks genetics may help explain what she has seen in her own practice.
"I have seen that psoriasis is linked with diabetes, which suggests that a genetic link may help explain why it's a lot harder to control diabetes in patients with psoriasis," said Dr. Doris Day. She is a dermatologist at Lenox Hill Hospital in New York City.
"We are understanding more about psoriasis and coming up with better treatments for it," she said. "If you have psoriasis, you need to see a dermatologist, a cardiologist and an endocrinologist to make sure you have other conditions under control," Day advised.
SOURCES: Ann Sophie Lonnberg, M.D., University of Copenhagen, Denmark; Joel Gelfand, M.D., associate professor, dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia; Doris Day, M.D., dermatologist, Lenox Hill Hospital, New York City; April 27, 2016, JAMA Dermatology, online
Sleep Doesn't Come Easy to Those With Brain Injuries: MedlinePlus
Sleep Doesn't Come Easy to Those With Brain Injuries
And that may affect daytime performance at work or school, research suggests
WEDNESDAY, April 27, 2016 (HealthDay News) -- Many people who suffer a traumatic brain injury struggle with sleep problems they may not be aware of, Swiss researchers report.
These patients also can suffer daytime sleepiness for as long as 18 months after their injury, the small study found.
And these sleep problems may adversely affect daytime performance at work or school, the researchers said.
"Sleep-wake disorders are highly prevalent after traumatic brain injury of any severity but are difficult to diagnose because many affected patients are unaware of their disorder," said lead researcher Dr. Lukas Imbach.
It's not known why sleep problems in traumatic brain injury patients are underestimated, he said.
Every year in the United States, 1.7 million people suffer a traumatic brain injury, and evidence suggests that number is rising worldwide, the researchers said.
Sleep problems are known to be related to mood changes and depression, and also to learning and memory difficulties, said Imbach, who's with the department of neurology at University Hospital Zurich.
"A link between these neuropsychiatric problems and sleep disturbances after traumatic brain injury is absolutely possible, although our study did not test this hypothesis," he noted.
This study provides evidence that sleep-wake disturbances after traumatic brain injury persist over a long period of time, Imbach said, but they are neglected by the majority of affected patients.
"Therefore, we believe that our observations are important for any clinicians and neurologists involved in the management of [brain] trauma patients," he said.
The report was published April 27 in the journal Neurology.
For the study, Imbach and his colleagues followed 31 people for 18 months who had experienced a first traumatic brain injury. Their injuries ranged from mild to severe. The researchers compared these patients with 42 healthy people.
Imbach's team found that 67 percent of the brain-injured patients suffered from excessive daytime sleepiness, compared with 19 percent of healthy people. In addition, when asked about sleepiness during the day, people with a brain injury said they didn't feel any sleepier than those without a brain injury.
People with mild traumatic brain injury were as likely to have sleep problems as people with severe brain injury, Imbach said. No other medical conditions accounted for these sleep problems, he said.
The researchers also found that brain-injured patients needed an average of eight hours of sleep a night, compared with healthy people, who needed an average of seven hours of sleep each night.
Dr. Brian Edlow is a member of the neurocritical care staff at Massachusetts General Hospital in Boston. "Doctors who take care of patients with post-traumatic sleep disorders often rely on patients to report their own symptoms when deciding whether to perform a formal diagnostic sleep study," said Edlow, who co-authored an accompanying journal editorial.
"However, if patients are not recognizing their own sleep disorders or their own daytime sleepiness, we as clinicians need to rethink our approach to the assessment and diagnosis of post-traumatic sleep disorders," he said.
Earlier studies have suggested that as many as 50 percent of patients with traumatic brain injury experience sleep disturbances or daytime sleepiness. And, since many of these patients may not recognize their own symptoms, the fundamental question is whether all patients with traumatic brain injury should be tested for sleep problems, Edlow said.
Additional studies are needed to establish the link between sleep-wake disturbances and impaired daytime performance at work or school, which is the most important indicator of how these disturbances are affecting a patient's quality of life, Edlow said.
SOURCES: Lukas Imbach, M.D., department of neurology, University Hospital Zurich, Switzerland; Brian Edlow, M.D., neurocritical care staff, Massachusetts General Hospital, Boston; April 27, 2016,Neurology
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With plenty of great coupes on our lot, you can test drive whatever fits your needs. Discerning drivers will appreciate the 2017 CADILLAC ATS. It offers the latest in technological innovation and style. Familiarize yourself with the 2017 Chevrolet Corvette. Settle in and experience the rush! Lastly, experience driving perfection in the 2017 Chevrolet Camaro. Both practical and stylish! We have the vehicle you've been searching for at a price you can afford. Please don't hesitate to give us a call.


text:
The Delphic League is a high school athletic league that is part of the CIF Southern Section.

Members
 Crossroads School
 Milken High School
 Marshall Fundamental Secondary School
 Vernon Kilpatrick Camp School, aka Kilpatrick High School
 Brentwood School (Los Angeles, California)

References

CIF Southern Section leagues


text:
import {
    Component, Input, Output,
    OnChanges, SimpleChange
} from 'angular2/core';
import {Spy} from './spy.directive';
import {LoggerService} from './logger.service';

@Component({
    selector: 'my-counter',
    templateUrl: 'app/lifecycle-hooks/counter.component.html',
    styles: ['.counter {background: LightYellow; padding: 8px; margin-top: 8px}'],
    directives: [Spy]
})
export class MyCounter implements OnChanges {
    @Input()
    counter: number;

    changeLog: string[] = [];

    ngOnChanges(changes: {[propertyName: string]: SimpleChange}) {
        if (this.counter === 0) {
            this.changeLog.length = 0;
        }

        let prop = changes['counter'];
        let cur = prop.currentValue;
        let prev = JSON.stringify(prop.previousValue);
        this.changeLog.push(`counter: currentValue = ${cur}, previousValue = ${prev}`);
    }
}

@Component({
    selector: 'counter-parent',
    templateUrl: 'app/lifecycle-hooks/counter-parent.component.html',
    styles: ['.parent {background: gold;}'],
    directives: [MyCounter],
    providers: [LoggerService]
})
export class CounterParentComponent {
    value: number;
    spyLog: string[] = [];
    private _logger: LoggerService;

    constructor(logger: LoggerService) {
        this._logger = logger;
        this.spyLog = logger.logs;
        this.reset();
    }

    updateCounter() {
        this.value += 1;
        this._logger.tick();
    }

    reset() {
        this._logger.log('-- rest -- ');
        this.value = 0;
        this._logger.tick();
    }
}

redpajama_set_name: RedPajamaGithub


text:
"Ghost" by @KaceyFifield and #Little Rain gets a deep melodic future bass remix by @JayB1rdmusic
KACEY FIFIELD & LITTLE RAIN, "Ghost" (Jay Bird remix)
It happens now and again, but to be upfront, I had a bit of a "matchmaking" hand in how this remix came to be. Tipsy Records was looking for a remixer who could put an original spin on their summer electronic ballad release "Ghost" by Los Angeles singer/songwriter Kacey Fifield and South Korean electronic dance producer Little Rain (read my original blog post). I've written about Jay Bird's releases several times over the past few years and have seen his style progress as an electronic dance producer to include genres like house and future bass. So I thought that "Ghost" would be a great song to see where he could take it. Jay Bird clicked with the song and got the green light for the remix. Hearing the results, I'm so pleased at what Jay Bird achieved, taking nothing away from the emotional and detailed melodic qualities of the original, and applying some harder future bass bounce and additional synth elements to give "Ghost" an unanticipated lift. This remix will continue to appeal to Kacey's many young fans, who can sway and get lost in the changed-up melody of the chorus, and is a nice segue into the future bass genre for all of the artists, where it would not be out of place played along with music by Illenium, Seven Lions and others at a stadium concert or festival.


I started my thrifting/refinishing journey 3 years ago and I have learned so much about fast fashion and unethical clothing production. I like to think that now that I am so much more informed, I am making conscious efforts to shop wisely and ethically. I certainly feel that my love of all things vintage, retro and antique, along with my efforts in transforming and refinishing once-loved pieces are, in some small way, inspiring others to reuse and restyle instead of dumping things in the trash. I firmly believe in buying a good quality piece, even if it means second-hand, old, or waiting to save up for it if it's not affordable right away.
I almost never shop at Walmart or any of its competitors for the same reasons that I don't buy fast fashion. This got me thinking about places like IKEA. The Swedish furniture and home accessory manufacturer famous for its affordable (aka cheap) products, are very appealing to those on a budget, especially to those just starting out on their own and looking for a way to decorate and outfit a new house or apartment without breaking the bank.
I understand the appeal. The stores are bright, well-organized and staged in a way that any 20-something can picture the popular Klippan sofa as a modern, sleek place to sit and relax. I don't know if you ever noticed, but stuff at IKEA is a lot smaller than any old pieces. This can certainly be a factor in the decision making process because they seem to be building smaller houses and condos these days. Naturally, smaller houses mean smaller principal rooms and I know that vintage and antique pieces can be quite large.
Or how about the MALM bed? Young sophistication, right?
So I decided to do a little research, because, I admit, I have bought a few things from IKEA myself. The odd storage bin and what not, but I've never bought anything as big as a bed, a sofa, a night stand or even the BILLY bookcase.
I wanted to learn more about their carbon footprint, in particular. I'm sure we've all heard the expression: IKEA is Swedish for crap (or was it Mr. Restyle that came up with that line? In any case he's always saying it when someone mentions IKEA). What exactly is their stuff made of? What are their work ethics? What is so appealing about a dresser or a bed that I have to transport home and put together myself following a diagram and using a bunch of little tools that IKEA provides me with? What makes someone choose the MALM over a vintage, retro or antique piece?
IKEA is the 3rd largest consumer of wood, behind The Home Depot and Lowe's.
This actually surprised me a little because I can think of so many manufacturers and businesses where I would expect to see a huge consumption of wood. From my research, I have learned that the wood comes mostly from eastern Europe and the far east of Russia where, according to Ellen Ruppel Shell, author of Cheap: The High Cost of Discount Culture "wages are low, large wooded regions remote, and according to the World Bank, half of all logging is illegal." IKEA president and CEO Anders Dahlvig asserts that the timber his company uses is harvested legally, and the company does employ forestry experts to monitor the company's suppliers. But Shell points out that IKEA has only 11 forestry monitors, not nearly enough to keep a watchful eye on all those suppliers worldwide, and five of those specialists are devoted to China and Russia, a vast spread of territory by itself.
OK, but what kind of wood? You're not going to find walnut or cherry there! Most of IKEA's furniture is made from wood composite, aka pressed wood, fibreboard, particle board. That's right-particle board, so it's fair to say IKEA stuff is modern looking but not long lasting and in a world where people swap things out every few years anyway, who cares right? Yikes! I have huge problems with this. What happened to us? We used to cherish a piece that was in the family, passed down from generation to generation. The sad truth is that the young generation doesn't want any of our stuff! Whatever happened to pride of craftsmanship?
IKEA operates 373 stores in 47 countries. their website contains 12,000 products and in 2010, $23.1 billion worth of goods were sold. IKEA was founded in Sweden so all of their furniture is made in Sweden right?
Wrong. Everything is designed in Sweden but IKEA mostly manufactures in developing countries to keep costs down. China accounts for about 2½ times as much supply as Sweden.
IKEA produces affordable, stylish furniture and accessories. They even name all of their pieces, so they must really care.
People cannot possibly be conditioned to think green or to consider buying second-hand or antique. They must have what everyone else has. Everyone must look the same and companies like IKEA don't have a responsibility to their consumers.
I think a company's values, ethics and message actually make a huge impact, especially on young people. If IKEA's message weren't that we should just throw old things away and go shop in their store, then maybe people would think twice about buying cheap, poorly made stuff that they will toss in a couple of years.
Young people can learn to appreciate good quality, timeless pieces. They can be taught to fix that which is broken and the best of all? They can put together a place of their own that will not be found anywhere else.
Think back a few years before all of these fabulous paint products were readily available. Nobody was painting furniture or distressing it. Now it's all the rage. It's unique. It's sturdy. It's old and will last another hundred years and yes, it can fit into a modern home. All it takes is a bit of creativity and a some work.
I've only touched on a few points in this post but the topic really resonated with me. I am sure there is more to discuss on this topic. Would love to hear your thoughts.


text:
Q: Excel hardcode, subnet value that increments im currently trying to figure and formula that can help me.
I want to receive a subnet from a costumer Ex(100.100.100.0 or 10.200.200.20)
And incremente based on the value given.
So in the first row it will always be the value given +1 (100.100.100.1 or 10.200.200.21).
Second row  the value given +2 (100.100.100.2 or 10.200.200.22)
And so on.
Last one base value +14(100.100.100.14 or 10.200.200.34)
I wanted this hardcoded(no macro) for the excell sheet , and only change the last octet. Im havig ptrouble as the string size can chage.
This is used to devide the ip in a /28 subnet.

A: Assuming your IP number is in cell A1, enter the following array formula in cell A2...
=LEFT(A1,MAX(IF(MID(A1,ROW(1:15),1)=".",ROW(1:15)))-1) & "." & RIGHT(A1,LEN(A1)-MAX(IF(MID(A1,ROW(1:15),1)=".",ROW(1:15),0)))+1

To confirm the formula be sure to use CTRL-SHIFT-ENTER.
Now copy cell A2 downward as far as you need to.

A: This is the formula you are looking for:
=CONCATENATE(REPLACE($B$2;13;100;"");ROW(A1)+RIGHT($B$2;LEN($B$2)-SEARCH(".";$B$2;12)))
And with this input the output should be as shown in the image below:

The solution concatenates all the characters until the last "." with the sum of the number of the row it is and the number after the last ".".


text:
New study shows marine 'networks' can protect fish stocks
MIAMI — University of Miami (UM) Rosenstiel School of Marine & Atmospheric Science faculty were part of an international scientific team to show that strong links between the corals reefs of the South China Sea, West Pacific and Coral Triangle hold the key to preserving fish and marine resources in the Asia-Pacific region.
Rosenstiel School researchers Drs. Claire Paris and Robert Cowen and colleagues from the ARC Centre of Excellence for Coral Reef Studies at James Cook University and University of California – Los Angeles, have established that the richest marine region on Earth — the Coral Triangle between Indonesia, Malaysia and the Philippines — depends vitally for its diversity and resilience on coral and fish larvae swept in from the South China Sea and Solomon Islands.
"By evaluating the directionality of larval transport over multiple generations, we could describe the signature of the extraordinary genetic diversity of the Coral Triangle. Preserving diversity is key to the health of marine systems," said Claire Paris, Rosenstiel School assistant professor of Applied Marine Physics. "This kind of work will help us anticipate and manage changes of connectivity networks in the future."
The authors provide evidence showing the regions' biology is closely inter-connected suggesting that it is in the interests of all Asia-Pacific littoral countries to work together more closely to protect it.
"Maintaining the network of links between reefs allowing larvae to flow between them and re-stock depleted areas, is key to saving coral ecosystems threatened by human pressure and climate change," said the paper's lead author Johnathan T. Kool of James Cook University, who is also an alumnus of UM. "The science shows the region's natural resources are closely interconnected. Nations need to cooperate to look after them — and that begins with recognizing the resources are at risk and that collective action is needed to protect them."
The Coral Triangle is home to more than one third of all the world's coral reefs, including over 600 different species of reef-building coral and 3,000 species of reef fish. These coral ecosystems provide food and income for more than 100 million people working in marine-based industries throughout the region.
Six nations within the Coral Triangle — Indonesia, the Philippines, Malaysia, Papua New Guinea, The Solomon Islands and Timor L'Este — are now working together to strengthen coral reef governance and management, under an arrangement known as the Coral Triangle Initiative.
The paper, titled "Connectivity and the development of population genetic structure in Indo-West Pacific coral reef communities" by Johnathan T. Kool, Claire B. Paris, Paul H. Barber and Robert K. Cowen is available online and will be published in the March issue of the journal Global Ecology and Biogeography.
About the University of Miami's Rosenstiel School
The University of Miami's mission is to educate and nurture students, to create knowledge, and to provide service to our community and beyond. Committed to excellence and proud of the diversity of our University family, we strive to develop future leaders of our nation and the world. Founded in the 1940's, the Rosenstiel School of Marine & Atmospheric Science has grown into one of the world's premier marine and atmospheric research institutions. Offering dynamic interdisciplinary academics, the Rosenstiel School is dedicated to helping communities to better understand the planet, participating in the establishment of environmental policies, and aiding in the improvement of society and quality of life. For more information, please visit www.rsmas.miami.edu.
Categories Blog Entry, Earth, Energy & Environment, Health, Life & Non-humans Post navigation
Listening to music is biological
HIV makes protein that may help virus's resurgence


text:
A Question of Quality
Sean Milmo
Pharmaceutical Technology, Pharmaceutical Technology-07-02-2017, Volume 41, Issue 7
Greater transparency and reliability of information are needed in the quality assessments of biosimilars.
The size of the European biosimilars market is accelerating rapidly as government-funded healthcare services increase their support for these medicines in an effort to reduce costs. Sales of biosimilars in Europe has tripled in the past five years (1). In 2015-2016, they soared by approximately 50%, according to figures from QuintilesIMS, the US-based international healthcare services company that has been carrying out studies on the European biosimilars market for the European Commission, the European Union executive (1).
By March 2017, 26 EU-approved biosimilars were available in the European market, 10 years after the European Medicines Agency (EMA), the EU's centralized licensing body, authorized its first biosimilar. In 2016, Europe accounted for 87% of global sales of biosimilars, underlying its world leadership in the development of the medicines, particularly in the regulatory procedures for establishing comparability between biosimilars and the original products. The biosimilars sector in Europe, which is still in its infancy, has now reached a stage where more information about these regulatory procedures needs to be provided to stakeholders, particularly healthcare professionals, if the strong momentum behind biosimilar sales is to be maintained.
Physicians are not greatly concerned anymore about the safety of biosimilars. In the 10 years since they have been on the European market, the EU's pharmacovigilance monitoring system has not identified any marked differences in the types of adverse effects between biosimilars and their originals. But prescribers are concerned about the challenges of convincing patients about security of treatments by biosimilars for new therapeutic areas such as autoimmune diseases, oncology, and especially chronic conditions.
Quality attributes
This necessity for greater transparency is being centred on the way the quality attributes of the manufactured biosimilars are compared with those of the original or reference product. Manufacturers are required to establish that their biosimilars have sufficient levels of similarity in order to be authorized.
These attributes mainly comprise physicochemical and functional properties such as molecular structure, protein modifications, and biological activity. Because the drugs are biological, there are inevitable differences. But for a drug to be "highly" similar so that it can be licensed as a biosimilar, these differences must not result in inferior levels of safety and efficacy to the reference product.
With biologicals in which the active substance is a protein, the biosimilar and reference product must contain the same protein (i.e., amino acid sequence) and the same three-dimensional structure or folding of the protein. In the finished medicine, certain differences, such as excipients used in formulations and in the administration device, are allowed because they have no effect on safety and efficacy.
Quality assessments
Quality assessments have become such an essential part of the process for approving biosimilars that in most cases once a biosimilar has proved itself to be highly similar on a quality basis to regulators, investigation of clinical studies to establish safety and efficacy has not been required. "By demonstrating biosimilarity [at the quality level], a biosimilar can rely on the safety and efficacy experience gained with the reference medicine," says an EU guide to biosimilars for healthcare professionals published jointly in May 2017 by EMA and the European Commission (2). "This avoids unnecessary repetition of clinical trials already carried out with the reference medicine," it adds.
With quality having such a key position in biosimilars' authorization, healthcare professional organizations have been urging EMA to increase the transparency of the comparability exercise applied to quality data to show high similarity between biosimilars and their reference products. "Given the role of healthcare professionals on the front line of patient care, it is vital that they have access to reliable information on these medicines: what they are and how they are developed, approved, and monitored," says Professor Guido Rasi, EMA's executive director.
Biosimilars switching
When selecting biosimilars for patients, prescribers have tended to rely on the basic details in its summary of product characteristics (SmPC), which focuses on safety and efficacy information. A much more suitable communications vehicle on the quality aspects of biosimilars would be a group of documents known as the European Public Assessment Report (EPAR). In addition to the SmPC information, EPAR documents contain assessment reports on the scientific evaluation of the medicine at the time of approval and on major changes, such as the addition of new indications. Crucially, it integrates the whole comparability exercise covering the quality, safety, and efficacy of the biosimilars. By extending EPAR to give more information on quality aspects, EMA could deal, for example, with concerns about lack of appropriate data when prescribers switch patients from one biosimilar to another.
In a joint position paper (3) on biosimilars switching issued in March 2017, the European Federation of Pharmaceutical Industries & Associations (EFPIA), European Biopharmaceutical Enterprises (EBE), and International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) complained about the lack of comparability data between biosimilars for prescribers. "This type of data may not be available to stakeholders when evaluating a switch between two biosimilars of the same reference product," the three organizations said (3).
Now EMA has revealed it is testing a scheme for giving more technical information on quality comparability data in the EPAR of an unidentified biosimilar that the agency has recently approved. "This initiative is part of the agency's efforts to ensure that healthcare professionals have access to reference information on the science and regulation underpinning the use of biosimilars and thereby increase healthcare professionals' and patients' confidence in the approval process for biosimilars," an EMA spokesperson told Pharmaceutical Technology Europe.
"Once the EPAR for the medicine has been published later this year, EMA will conduct a small survey among relevant healthcare professionals to find out whether this additional information is considered helpful."
Analytical and statistical methods
At the same time, EMA is making moves to raise the efficiency of analytical methods for the collection and assessment of quality data. In February 2017, it launched a scientific advice pilot project to help biosimilar developers assess existing data. The agency will advise developers on the studies they should conduct on the quality, analytical, and functional data that they already have available. EMA's scientific advisors usually do not make suggestions on the assessment of existing data. The agency plans to run the pilot until it has undertaken six scientific advice requests, with a maximum of one scientific advice request being accepted per month.
EMA is also considering ways of gaining greater value from the statistics generated by quality assessments in the development of drugs, particularly biosimilars. Conclusions or inferences could be reached from data rather than using the statistics merely in a descriptive manner to make measurements or to detect patterns.
The agency issued in March 2017 a reflection paper (4) on statistical methodology in comparative quality assessment to investigate to what extent the implementation of inferential statistical methods can facilitate comparative evaluations of quality data. The paper highlighted some current difficulties with quality assessments in biosimilars development with some experts being sceptical about what could be achieved with the help of statistics.
"From related discussions between [biosimilar] developers and regulators, it became evident that there is no common understanding what kind of statistical data analyses approaches would be considered suitable, if any, for comparison tasks involving quality attributes data," EMA said in the paper. Furthermore, the effects of quality differences on safety and efficacy can be difficult to measure. "The impact of differences at the quality level on clinical outcome--efficacy/safety/immunogenicity--is often hard to predict or quantify," the paper said.
Some of the concerns about quality data stem from the limitations of data sources when biosimilars have been produced in small commercial batch quantities over a relatively short period. "At first sight, it might seem straightforward to apply inferential statistical methods for comparing data from quality attributes," the paper continues. "But often severe limitations exist regarding practical applicability, given the specific circumstances relating to sampling and data collection. Hence, the question of whether the desired conclusion of similarity of products could indeed be inferred from often limited information from sample data remains difficult to answer on many occasions."
Biosimilars prescribing
Meanwhile, physicians in some parts of Europe are coming under growing pressure to prescribe more biosimilars as governments step up their efforts to drive down medicine prices by introducing tendering schemes for mass supplies of biologicals, including both originals and biosimilars. They are also offering incentives for doctors to prescribe lower-cost biosimilars through "gain sharing" projects under which at least some of the money saved is channeled into local healthcare budgets.
Nonetheless, the biosimilars market in areas of Europe remains fragmented. Levels of prescribing are high in Scandinavia but relatively low in Western European countries such as France and Spain and, despite recent rises in the availability of certain biosimilars, in Eastern Europe (5).
There are also huge contrasts in individual countries. In Italy, for example, uptake of biosimilars has reached close to 75% in the north but is as low as 10% in the south (6). Caution among healthcare professionals has been a major factor behind these differences. It remains an open question as to how much greater transparency and reliability in information on quality will help to change their attitude to biosimilars.
1. P. Troein, R.Logendra, Stephen Deitch, QuintilesIMS, "Market development in Europe and Globally-A perspective on biologicals and biosimilars," presentation at Medicines for Europe's Biosimilar Medicines Conference ( London, March 2017).
2. EMA and European Commission, Biosimilars in the EU-Information Guide for Healthcare Professionals (London, May 2017).
3. EBE, EFPIA, IFPMA, Considerations for Physicians on Switching Decisions Regarding Biosimilars (Brussels, March 2017).
4. EMA, Reflection Paper on Statistical Methodology for the Comparative Assessment of Quality Attributes in Drug Development, EMA/CHMP/138502/2017 (London, March 2017).
5. IMS Institute for Healthcare Informatics, Delivering on the Potential of Biosimilar Medicines (Parsippany, New Jersey, March 2016).
6. M. Uda, Italian Biosimlars Group, "The New Italian Procurement Law on Off-Patent Biological Medicines," presentation at Medicines for Europe's Biosimilar Medicines Conference (London, March 2017).
When referring to this article, please cite it as S. Milmo, "A Question of Quality," Pharmaceutical Technology Europe 29 (7) 2017.
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The stellar faculty and curriculum of the ASL/interpreting department provided me the means to develop the language and interpreting skills necessary to succeed.
"While a student at St. Kate's, I networked with seasoned interpreters in the field who subsequently became my colleagues," Quincy says. She also volunteered at Deaf community events, spending time at the Charles Thompson Memorial Hall, a social hall and meeting place in St. Paul for the Deaf. The experience helped her understand the cultural complexities of facilitating communication between Deaf and hearing people. She also made good Deaf friends.
Collaborative research with Gajewski Mickelson also helped Quincy's transition into the profession. In October 2012, the duo presented "Developing Ethical Competencies: 'Training' Interpreters to be Ethically Fit" at the national convention of the Conference of Interpreter Trainers in Charlotte, North Carolina.
Diploma in hand, Quincy Craft Faber left St. Catherine ready to start building a successful career as an ASL interpreter. Her first step: Earning her National Interpreter Certification, a hurdle she cleared immediately after graduation. The certification is required for all professional ASL interpreting jobs, and most St. Catherine alumnae eventually earn it.
Quincy credits St. Kate's with her burgeoning career as a full-time interpreter in private practice. "The stellar faculty and curriculum of the ASL/interpreting department provided me the means to develop the language and interpreting skills necessary to succeed," she says.
The program's emphasis on community involvement also helped Quincy make personal connections in the Twin Cities Deaf community. She still turns to that network today for job recommendations and referrals for interpreting jobs.


Left4Beer: Can drinking beer lead to malaria?
Apparently people that drink beer are more appealing to mosquitoes than people that drink water. This is the finding of a study that appeared in PLoS one. Subject either drank 1 litre of water or dolo. Dolo is a fermented sorghum beverage of about 3% ABV. Mosquitoes were more attracted to the body odour of dolo drinkers than water drinkers. This increased attractiveness of beer drinkers is apparently a new risk factor for contracting malaria.
The reason for this was not clear. It was thought that beer drinking increased certain odours that are attractive to mosquitoes. It was not due to increased body temperature or increased CO2 respiration. Apparently an increased body temperature also attracts bugs, that is why pregnant women tend get bit more.
The question for Canadians is whether a better bug catcher is a buddy sauced on Blue or some gadget from Canadian Tire? And will beer drinking increase your risk of becoming infected with the west nile virus? Maybe I will drink beer indoors.