text:
Listen, Liberal – Part I
by Peter Turchin
democrats, neo-liberalism, republicans, Russia
Ironically, it used to be the crazy fringe on the Right that were the breeding grounds for conspiracy theories ("birthers", "Clinton death list"). Now mass hysteria and conspirology are sweeping the crazy … Liberal mainstream?
Earlier this month Glenn Greenwald wrote a very important article, Leading Putin Critic Warns of Xenophobic Conspiracy Theories Drowning U.S. Discourse and Helping Trump. Greenwald's starting point is an article by Masha Gessen, which is also well worth reading. He writes:
The crux of her article is the point that has been driving everything I've been writing and saying about this topic for months: that this obsession with Russia conspiracy tales is poisoning all aspects of U.S. political discourse and weakening any chance for resisting Trump's actual abuses and excesses. Those who wake up every day to hype the latest episode of this Russia/Trump spy drama tell themselves that they're bravely undermining and subverting Trump, but they're doing exactly the opposite.
Greenwald pulls no punches. The Progressive Fake News sites that have been hyping up the Russia/Trump conspiracy are
no better – no different – than what Macedonian teenagers or Clinton Body Count sites are churning out. But it's being mainstreamed by prominent, establishment Democrats who have completely taken leave of their senses in the wake of Trump's victory and show no signs of returning to anything resembling sober, grounded reasoning any time soon.
Why are they doing it? Clearly, the Democrats are still in massive denial about why they really lost the presidential elections of 2016. They are looking everywhere except at themselves. But by buying into the Russia conspiracy theory they are setting themselves up for much worse. When this conspiracy collapses (I personally give less than 10% chance that there is any substance behind it), it would be a colossal reputational hit, from which they might not recover before the next round of presidential elections.
The Democrats should stop obsessing about the mythical "Siberian Candidate" conspiracy. Instead, they should read the remarkable book by Tom Frank, Listen, Liberal: Or, What Ever Happened to the Party of the People?
Listen, Liberal is a devastating critique of the mainstream Democracy, the Clintons-Obama Democrats, from "a person of vivid pink sentiments" as Frank describes himself. The true left in the United States are so microscopic that it's worth reminding my readers that the Democratic Party of 2016, when placed on the Right-Left spectrum of the last century or so, would occupy the right of the center position. In fact, although Frank's book is primarily addressed at the Democrats, it's worth noting that much of his critique aimed at "Liberals" applies to both mainstream Democrats and mainstream Republicans (but certainly not to Trump's supporters or, for that matter, Sanders' supporters).
What unifies mainstream American politicians of both parties is neo-Liberalism, as it is defined, for example, by George Monbiot:
Neoliberalism sees competition as the defining characteristic of human relations. It redefines citizens as consumers, whose democratic choices are best exercised by buying and selling, a process that rewards merit and punishes inefficiency. It maintains that "the market" delivers benefits that could never be achieved by planning.
Attempts to limit competition are treated as inimical to liberty. Tax and regulation should be minimised, public services should be privatised. The organisation of labour and collective bargaining by trade unions are portrayed as market distortions that impede the formation of a natural hierarchy of winners and losers. Inequality is recast as virtuous: a reward for utility and a generator of wealth, which trickles down to enrich everyone. Efforts to create a more equal society are both counterproductive and morally corrosive. The market ensures that everyone gets what they deserve.
According to Frank, one can boil down the difference between Liberals and Socialists (the true left) to two words: competition versus solidarity. By the way, the tension between competition and cooperation is a big topic that I explore at length in my book Ultrasociety).
Part II here
Peter Payne March 25, 2017 at 10:06 pm
Hmmm, interesting posterior, thanks. It's making two separate points; the second, which I agree with–I am a devout Berner (Hey, I'm from Vermont)–but I guess I am naive, I did not think the mainstream Democrats could so easily be characterised as Neoliberal. But, I have been bemused by the huge negativity still being directed at Bernie supporters by mainstream Dems.
The first point took me aback–I confess I was not thinking of the Russian connection in terms of fake news. The kids in Macedonia know what they are promoting is false, I do not know that "Progressive fake news sites" are consciously falsifying? The FBI IS investigating these connections, Flynn DID lie about his Russian contacts, Trump both has and denies having strong connections to Russia; I am not sure where your 90% belief there is nothing to it comes from? I am also not quite sure why you (or Greenwald) feel it would be so devastating for the Democrats to espouse a conspiracy theory? It was no impediment to Trump taking the White House.
I have seen several articles recently from Democrats or portions of the Left lambasting the Democrats quite viciously for various mistakes. I think some of the critiques have validity (like Frank's), but I find the vehemence misplaced. Isn't this what the alert always tends to do–factionalise and attack each other for this or that? Whatever happened to…Cooperation?
Peter Turchin March 26, 2017 at 7:48 pm
Peter, did you read Greenwald's article? The question is not whether Flynn had Russian contacts, but why Trump won the election. Did the "rust belt states" like Wisconsin, Michigan, and Pennsylvania vote for Trump because they were brainwashed by Putin, or because the mainstream Democrats abandoned them? Would they vote for Trump, were Bernie the Democratic nominee?
Peter Payne March 26, 2017 at 9:15 pm
Actually no, I haven't read the Greenwald article, I am enmeshed in several deadlines, sorry. Taking the overall point that Democrats should not use the Russian connection to avoid looking at their abandonment of authentic Liberalism, Socialism, compassion, common sense, whatever we want to call it…Yes, totally on board.
But, that does not mean I consider the Russian connection a non-issue, to be dismissed a priori as fantasy. Seems to me there is good evidence Putin did want Trump to win, did attempt to influence the election, did promote fake (REAL fake) (OMG, has it come to this?) news to Clinton's detriment; there were multiple communications between those close to a Trump and those close to Putin. Likely Putin figured Trump would be soft on Russia and easy to manipulate. Were there explicit quid pro quos? Maybe. Implicit? Yes. Does all this matter? Yes. Could in help bring down Trump? Yes. Is it dangerous to the Democrats to push this investigation? I don't think so. Is all this the cause of Trump's victory? Probably not although it may have swayed the results. Does it define how the Democrats should be re-tooling? Absolutely not.
Daniel W March 28, 2017 at 10:41 pm
Peter T, if you look at both parties, everyone who is mainstream, not just democrats, are losing hold right now. It might be true that Putin's strategy, to fail cheaply and fail early as you have pointed out, might just have taken hold on a democracy that was already weakened. It doesn't matter who started it, all American politicians and their constituents must sharesome responsibilty for the conditions in which Trump could rise. People have told me that democracy functions when there is an election, and I say democracy functions when you vote for the person who wants to advance democracy. America as a country has lost its way, and there is no way blame can be put on Russia for that.
No, I really do agree, whatever Putin has been up to, he is not to blame for the American Zeitgeist–if there even IS an "American" Zeitgeist any more. I am quite happy with the Vermont one so far, but it sure ain't what I meet in other parts of this country.
Sorry that"posterior" should be "post"! My spellcheck has a dirty mind.
InnocentBystander March 25, 2017 at 10:36 pm
The thing that I find uncomfortable here is the need to define group differences as an argument about economics. That strikes me as a thing that is only recent in nature and is now in the process of decline.
steven t johnson March 26, 2017 at 8:43 am
Political parties in a plurality vote single member district system tend to organize themselves into two coalitions, which could be called the "Ins" and the "Outs." Duverger's law is one of the few proposed laws in political science that has held up well as I remember. It is rare that circumstances leaves everybody happy, so there will inevitably be an "Out" party. It is hard to imagine that any discredit from an absurd political campaign will abolish the need for the losers to band together. The "In" party will not remove the bipartisan structure lest an oppositional party emerge from the ruins of the "Out" party, who are merely rivals.
Further, the Russia campaign is simply tit for tat. The seemingly endless Republican campaigning about Benghazi, email server and Clinton Foundation are all exactly the same kind of innuendo about treason. If you do not disagree on political principles, what is left besides this kind of nonsense? The charges against Clinton had no more to do with reality than the Russia baiting of Trump, but the Republican Party hasn't been discredited. Quite the contrary, it has prevailed pretty much everywhere, except nationally.
I believe it is reasonable to think the primary reason for the triumph of the Republican Party in the states across the nation is the much cheaper costs of winning with money instead of popular mobilization. But a national election is way too expensive. Not even Trump could have done it without massive indirect financial support from mass media (and the advertising purchasers who tacitly approved it by not boycotting, the way they would have I think if for some bizarre reason the TV networks for instance had given Bernie Sanders so much attention.)
Or to put it another way, your formal objection that the Democratic Party should actually try to gain popular support by advocating policies that help people suffers from one slight difficulty: There's no reason to believe the current system can provide that many benefits to the majority of people, while at the same time, it is structured to provide benefits to wealthy people who have rigged the political system as much as possible to preserve their own position.
Your implied objection that vilifying Russia is an unprovoked threat to not just one man, Putin, but an entire nation, is of course correct. I suppose you could object that Russians are a part of Christendom as well, but politically the US is McCarthyite (to use a handy tag.) It is premised on anticommunism, and anticommunists hate the masses.
"the primary reason for the triumph of the Republican Party"
No, the 2016 elections were not the triumph of the Republicans. Trump ran against the mainstream Republicans as much, if not more, as he ran against the Democrats.
bob sykes March 26, 2017 at 9:03 am
The deeper problem is that the Democrats have become a racialist, anti-White party, to the extent that even Bernie Sanders, a traditional Marxist who emphasizes economic class over race, was pushed aside (literally, by BLM). Hillary was openly contemptuous of working class Whites, and they defected to Trump. Unless the Democrats can purge themselves of the racialists, working and middle class Whites will move into the Republican Party for the foreseeable future. Our whole politics will decline into racialist parties, and race will be the only criteria voters will use to choose representatives.
Hmm, I wouldn't apply the label "racialist" to the Democrats, nor "a traditional Marxist" to Sanders.
EdwardT March 27, 2017 at 7:53 pm
One of the nominees for the new Democrat leadership said white men should shut up. That was sexist and racist. No solidarity there. It's abuse. No wonder self-respecting white men, like Trump, with leadership abilities and ambitions for power, have long fled the Democrat fold, and will continue to do so.
The Republican Party only picked Trump up because they happened to be the party out of power. The neocon old guard didn't want him for the populism he represented but they couldn't stop the younger generation getting their way. And they will continue to do so because there is no countervailing trend. They could only have been stopped with power, but the people who would have stopped them are now out of power.
Right now the Democrats are only interested in virtue signalling to themselves and completely lack policy substance.
As for the Monbiot quote, the politicians (neoliberal at home, neocon abroad) are in actuality most concerned about protecting the rights of large corporations (they own) to compete against small and medium-sized businesses (that vote Trump). They are not interested in a market. They try to ban or otherwise discourage alternative news, alternative health, gun ownership (alternative sources of authority), alternative energy, alternative wealth (bitcoin, gold, silver) that would affect their power as a class. It's a racket.
steven t johnson March 27, 2017 at 5:00 pm
Let me clarify by amending "I believe it is reasonable to think the primary reason for the triumph of the Republican Party in the states across the nation is the much cheaper costs of winning with money instead of popular mobilization" to "I believe it is reasonable to think the primary reason for the triumph of the Republican Party in the state elections across the nation is the much cheaper costs of winning the smaller states with money instead of popular mobilization." You are of course correct that Trump is not part of the Republican Party politicians. ( I see him as one of the stockholders rousting management in a hostile takeover bid.) Nonetheless he will work with the Republicans, or be impeached. I do not think the Democratic Party will disappear on the state level because there isn't enough gravy to include everybody, thus the Out Party will endure, a lifeboat for wrecked hopes.
By the way, part of the reason for the intensity of the assault on Trump is that he lost the election. Winning the Electoral College makes him the legal president, but doesn't make him legit. The historical anomaly in 2000 was the way Gore rolled over. Nobody since Hamilton tried to lobby the Electoral College to spare us John Adams has anybody accepted the Electoral College vote as the legitimating vote.
InnocentBystander March 29, 2017 at 12:06 am
"By the way, part of the reason for the intensity of the assault on Trump is that he lost the election. Winning the Electoral College makes him the legal president, but doesn't make him legit."
Was Lincoln legit?
In my mind, the lack of legitimacy is partly a matter of the election being a slam-dunk for Clinton. It feels stolen somehow. In any case, I think that the electorate was planning on getting more frisky regardless of the result.
Yes, Lincoln was legitimate. He won the plurality by a sound margin, despite being kept off the ballot in the Deep South.
Clinton couldn't run convincingly against her own party's economic record, but the performance of the Obama administration overall has been thoroughly unsatisfactory for any but the owners. So I agree the electorate would have been fractious regardless of the Electoral College contraption.
Lincoln legitimate with under 40% of the popular vote? After all, it's not a matter of math but one of how the people feel afterwards.
Good thing they didn't have any unrest after the election.
What has been most interesting to me is how the gloves have come off in terms of groups taking sides. Practically all of the MSM has dropped the pretense of impartiality and my strong guess is that outright war is breaking out between factions in the bureaucracy. It's a reasonable side effect of putting an outsider in charge I think. Whether Trump is the immune system of Western Civilization kicking in or merely an aberration (or something else) is still up in the air.
Mike Alexander April 1, 2017 at 9:05 am
Innocent Bystander asks: Was Lincoln legit?
Well no, states started seceding a month after his election.
Chris Kavanagh March 29, 2017 at 12:21 am
I don't rate much of Glenn Greenwald's political analysis because it is almost entirely subservient to his ideological commitments and pre- and post- election that has meant his focus is primarily on criticising moderate left wing politicians, while making passing attacks at Trump and the rest of the right.
That he would be promoting the line that liberals are too focused on Russian conspiracies does not strike me as important or at all surprising because he, along with most of the far left commentariat, consistently downplay the failings of any source that is viewed as offering opposition to US hegemony.
That isn't to say that there isn't a problem with hysterical anti-Russian stories, nor to deny that Hillary could well have lost regardless of Russia's interference. Both of these points are valid. The problem is the leap from there to painting all concern over the Trump administration-Russian connection as a hysteria induced distraction. That doesn't seem to follow logically.
Russia did seek to interfere with the election in favour of Trump, as has been pretty well documented (see for example, http://www.esquire.com/news-politics/a49791/russian-dnc-emails-hacked/) and Trump has been uncharacteristically consistent in his praise of Putin. Senior members of Trump's cabinet have also already had to resign due to Russian related issues and there are clear indications that more damaging findings are forthcoming. Consequently, this doesn't seem so much as a distracting side issue, as a serious consequential thorn in the side of the Trump administration.
That Trump is some Russian Manchurian candidate who personally takes orders from Putin is a fanciful, distracting, conspiracy theory. That the Trump campaign was aided by Russian efforts and key figures in the campaign/administration have historical links and potentially conflicting ties with Russian interests is a pretty view in the face of current evidence.
The lessons of the election of Trump that the Democrats need to learn unfortunately seem voluminous but also tend to fall neatly into the pet issues/ideological views of whoever is commenting. For me, it seems worth recognising that despite selecting the most unpopular Democratic candidate in modern history the Democrats very nearly won that very rare third term. Trump might win a second term but I think he is going to face an uphill battle in 2020 given that he will have had 4 years of being the insider and won't be able to count on an unpopular opponent. The midterm elections should serve as a useful indicator of whether the anticipated political patterns are in effect.
The beautiful thing about using foreign influences as a hammer on your opponents, and there's nothing new here I would guess, is that it's always true. You can always turn up evidence on Saudi, Mexican, Israeli, British, Russian, and (probably) Sumerian money and influence on US elections and policy.
Part 2 is to choose up teams. Apparently Russia, Israel, and a post-EU Great Britain (plus nationalist efforts in other EU ex-nations) are on Team Red, and Mexico plus the various Arab nations (and perhaps third world nations generally) are on Team Blue. It could all change in a minute which shows how vacuous this all is.
In the end, I suspect that everyone knows what side they are on without bothering to think about policy. The interesting part is trying to define the (probably) emotional dividing line. That strikes me as the heart of any study of a predictive nature.
Chris Kavanagh March 29, 2017 at 2:14 pm
There is always foreign influence but its a non-sequitur to suggest that therefore there is no real need for it to be a topic of concern or that all foreign powers are engaged in equally damaging efforts. I didn't notice Mexican state sponsored hackers having much of an impact on the campaigns this time round. I also can't think of any other US election in recent history where one candidate so readily repeated the talking points generated by a foreign state's propaganda. You don't need to see the world in binary black and whites to recognise conflicting goals between nation-states or power blocs.
I don't want to drag into an argument about the actual (rather than an over-exuberant news media view) extent of Russian cyber-efforts in the US general election, there's scads of that about, but I do have to say that there's no comparison in the scale of the effect when comparing countries.
Mexico and Israel, to pick two, exert vastly more steering on the US political scene than the Russians could ever hope to.
So, if foreign influence is a bad thing, how would you go about limiting it? To some extent it's unavoidable since people will often vote in favor of their own native culture (perhaps a generation or three removed) rather than national interests, but perhaps money could be removed as an issue. I'm afraid that funds will always find a way, though.
sglover April 4, 2017 at 6:29 pm
I agree with your comment overall, but I don't think that **Mexico** has an outsize, or even very large, influence on the U.S. government. It's a large state that directly borders the U.S. A significant fraction of U.S. citizens and residents can trace their ancestry to Mexico. And despite all this, when it comes to foreign policy Mexico pulls nothing close to the weight of, say, Israel or Saudi Arabia or Britain in D.C. .
R. N. England March 29, 2017 at 3:43 am
Capital always influences the governance of any country. That's not saying any more than, "You can hire a very effective propagandist if you pay him enough". Americans should wake up to the fact that there is plenty of non-American capital floating around the world, and that it will influence how the US is governed. Some of it is Russian. Big deal. For a long time now, the rest of the world has had to put up with interference from American capital in how their countries are run. Before that It was British.
That strikes me as a reasonable post.
One new difference might be the quality of modern propaganda. It doesn't seem to me that people have built up immune systems to individually targeted web-borne media as quickly as the media itself has improved.
Mix that up with what appears to be a tsunami of Dunning-Kruger style thinking as of late, and you get a perfect storm.
Peter Payne March 30, 2017 at 12:15 am
What's Dunning-Kruger, excuse my ignorance?
InnocentBystander March 30, 2017 at 4:15 pm
It's a bias (named after the study) in which low ability people mistakenly believe themselves as high ability. One notion is that people can't see their own ineptitude if they are poor at something.
My own reference to it is in terms of the political certainty you see scattered about the internet. People with no background in those domains are tremendously sure about the structure of healthcare policy, tax law, immigration law, etc. This is all far beyond idle tavern banter. I've been particularly enjoying the huge number of computer security experts holding forth on Russian cyber efforts as of late.
"…where all the children are above average…"
John Lilburne March 29, 2017 at 11:28 am
Peter you must be careful …having Russian background and calling the democratic party nutty with conspiracy theories … you are obviously a Putin mole and your site a fake news site ……………….
stacking the deck of political violence heavily in favour of the left in Phoenix, leftist Shock Troops out on the prowl.
OK excuse my ignorance or naïveté, but WHAT exactly am I watching here?!? Is this really what it purports to be?
EdwardT March 30, 2017 at 10:16 am
Larping at revolutionaries?
Either that or it's some kind of group insanity effect. These individuals probably couldn't fire these weapons. What are they doing with them and what do they think marching around with them is going to achieve?
It's funny that they object to being covered by the journalist rather than court his attention.
It's possible there is some really impossible-to-guess logical reason like they were filming a scene from a movie they were making.
That's especially true given that the journalist is from the New Times, a famously left-wing weekly.
As a PR stunt it seems at least medium effective, although I expect that most of those people are better at manipulating spoons and forks than they are firearms.
Vladimir Dinets March 29, 2017 at 9:20 pm
Come on, it's been obvious since the RNC that Trump is a Russian spy. I can bet you $100 that the whole story is not fake news.
Of course it's fake news, the whole story is a false-flag job to cover up the Swedish connection. Swedish Leftist Hans Linde–you know, they call him "Small" Hans–is pulling Trump's strings. Don't tell anyone!
Vladimir Dinets March 30, 2017 at 1:57 am
Just wait a few more weeks 🙂
As a side note, looking at the periodicity of this chart:
http://www.zerohedge.com/sites/default/files/images/user5/imageroot/2017/03/27/CBO%20forecast.jpg
and ignoring the chicken vs. egg question (does debt cause political uproar or visa versa…darn those feedback loops), I have to wonder if the real story isn't the increase in amplitude.
Pingback:	Peter Turchin Listen, Liberal – Part II - Peter Turchin
Roger April 3, 2017 at 1:35 pm
The widespread current use of the "neoliberal" label is primarily a dishonest rhetorical trick. It is used to define everything bad, (real or imagined) in economics and politics of the non-Socialists. Since virtually nobody defines themselves as a neoliberal, this allows those using the label to define them at their convenience. Crony capitalism. Bail outs. Excessive regulations. Inadequate regulations. Negative externalities. Any destruction that comes with creative destruction. Everything bad or stupid out of any party.
Everything bad in economics and politics can be folded into neoliberalism. If Monbiot had defined it as people who kill kittens and hate babies, then who will say he is wrong? Few are claiming they are neoliberals, and if they did claim the title and dispute your definition, you and Monbiot would just accuse them of a secret agenda. The proof — just look to all the dead kittens!
Neoliberalism is to a great extent just the latest conspiracy theory. It is the current fad version of the Illuminati. The evil Mont Pelerin Illuminati!
I could try to point out the absurdity of Monbiot's definition, but what is the point? At best I could clarify how this does not describe classical liberal or libertarian beliefs. But again, you could just argue that of course it doesn't represent either of these, it represents the true ideology in the shadows behind these fostered by those kitten killers with secret handshakes and funny hats with tassels.
This tactic of taking liberties to negatively define a group which doesn't really exist is a horrible form of argumentation and adds nothing to the intelligent dialogue. It destroys dialogue and reason, and sows confusion and propaganda.
If someone wants a legitimate argument on the value and benefits of real classical liberal beliefs over the actual horror and failure of real Socialism, then I am all for it. Truth is they already lost that argument, and they know it. Thus they have to change the terms of the debate against an imaginary nemesis.


text:
Oculus introduces stereo shading reprojection for UNITY
By Fri13
August 7, 2017 in Virtual Reality
https://developer.oculus.com/blog/introducing-stereo-shading-reprojection-for-unity
In our Unity sample, this idea has proven to work very well for pixel shader heavy scenarios, saving ~20+% GPU cost per frame for our test scene.
Doesn't this sound more like the Nvidia demoed calculation trick where some shaders/pixels were left out from being processed when they weren't in the view?
The idea was suggested for ED by some community members, but as it was a proprietary for Nvidia, it would have left AMD users out.
But this sounds more like a "neutral" one (yeah, still from Oculus, possibly leaving Vive users out) as it isn't hardware locked.
Or then it is just a optimization for Unity engine.
But it is interesting to see how much improvements for rendering there could be achieved without a new hardware. And I think that is important that we are not in the hardware race where new hardware is required to be bought every 2-3 years, but we could get 4-5 year old hardware to perform at least in above minimum performance levels.
i7-8700k, 32GB 2666Mhz DDR4, 2x 2080S SLI 8GB, Oculus Rift S.
i7-8700k, 16GB 2666Mhz DDR4, 1080Ti 11GB, 27" 4K, 65" HDR 4K.
These solutions sound appealing but the real trick for us, DCS users, is when ED will update its engine to adopt these technologies. Some of them could already vastly improve the performances of the game but are far from being adopted.
Wag' stated a few weeks back during an interview that they don't have a lot of manpower available. I assume then, that they can not handle several major overhauls of their product at the same time. This situation leads us to a whole different topic : ressource management and projects priority. At this very moment, I don't understand how a company with so few people can afford to engage in so many different projects : developing a new module, developing a new map, developing new assets for a new era while new/updated assets for the current era would be more relevant, updating current maps, etc ...
Don't get me wrong, I love what ED has in mind, this is one of the most exciting game out there. But is ED being too ambitious to pretend they can tackle all of this ? Right, in the long term they'll probably pull it off, but in the meantime, we have to bear the consequences of their policy. I really hope that the upcoming 2.5 will be a game changer and that ED will be able after its release to support new technologies.
It's called using specialists in their fields. They have map specialists, 3d modelling specialists, and systems specialists.
This has been stated by them on several occasions, but clearly the message simply falls on deaf ears, or people don't bother to research their subjects properly.
How ED choose to conduct themselves isn't subject to armchair analysts giving sage advice - advice that is generally given in complete ignorance of the realities of their resources and how they use them.
Considering how short a space of time VR has been in the public arena, you can hardly blame ED for not being on the ball. Like EDs own software, VR is currently a moving target, and chasing rainbows probably isn't going to prove productive until the industry settles down to a set of standards that can be confirmed as the way forwards.
Much as we'd all like to have cake today, the reality means we will have to curb our enthusiasm a little, and leave the developers to assess and decide in their own way, and time what to pursue, and what to simply monitor.
ED Beta Testers
This is of no use (right now) until they can uncouple or change the CPU processing thread from the graphics processing which is bottlenecked inside EACH processed frame. The graphics aren't the issue, the engine is. Or to be more precise, the load on the engine is tied to the frames and this hurts rendering immensely. Simply put, experience multiplayer scripted servers or experience single player with no objects. Night and day for frames.
After all the CPU multi threading conversations over the years, and a consistent "the improvements would be minimal" story, ED actually said this is on their radar to do, very recently. But that wasn't quite the same argument.
If that time comes, you could consider optimising graphics, right now they have one old engine not using it much and a new engine that needs optimised and are stuck between a rock and a hard place. And plenty of players wondering how we could ever scale the simulation up to a reasonable amount without destroying performance.
SIMPLE SCENERY SAVING * SIMPLE GROUP SAVING * SIMPLE STATIC SAVING *

redpajama_set_name: RedPajamaCommonCrawl


involved in carrying the session.
entities in order to correctly bill for services.
simple mechanism to exchange this billing identifier.
case" per section 4 of RFC 5727.
segments and needs to pass charging information between them.
indicator that is passed between the parties.
Typical values for the "npi-value" are listed in Appendix A.
Typical values for the "noa-value" are listed in Appendix B.
This document defines a private SIP extension header field.
mechanism could be TLS-encryption of the SIP signaling stream.
also made to narrative text.
Revision -04 is purely a refresh as -03 expired.
Revision -03 is purely a refresh as -02 expired.
this document forward soon to put closure on it.
tweaks to this "Changes" section of the document.
info" and is identical to "draft-york-sipping-p-charge-info-15"
looked like he was also employed by Sonus Networks.
NAME CHANGE - The document is now "draft-york-dispatch-p-charge-info"
to reflect the fact that the SIPPING Working Group no longer exists.
individual with no connection to his employer.
was changed to 7 years, to reflect the first usage around 2005.
address missing references in the text.
o  Numerous other tweaks to the text for readability.
Revision -13 has no changes to content and was issued as -12 expired.
o  Modification of Appendix B to reflect ANSI T1.113 values.
Charge-Info they are represented in decimal notation.


text:
Home > About us > Reflections on the network
Roger Street, PI, University of Oxford
When done well, the work of a knowledge exchange network is virtually invisible, but the added value is evident.
The Adaptation and Resilience in the Context of Change (ARCC) knowledge exchange (KE) network finished at the end of April 2018. Funding from EPSRC (EP/G036586/1, EP/L005700/1) enabled a coordination team with diverse and complementary skills and expertise to facilitate engagement across the boundary between researchers, policy makers and practitioners working on adaptation and resilience in the built environment and infrastructure sectors.
The ARCC network was originally funded (2009–2013) to support a rolling portfolio of EPSRC-funded research projects (20 projects, £50m investment). The coordination team worked directly with researchers and a wide range of policymakers and practitioners to enhance and add value to academic outputs by building on and going beyond the impact activities undertaken by individual research projects. This approach enabled trusted relationships to be established. Further engagement was enhanced through a comprehensive programme of knowledge exchange events to foster greater awareness and understanding across the communities. Specific events focused on single issues of direct relevance to stakeholders and/or researchers, whilst broader community events such as the ARCC Assemblies enabled more cross-cutting discussions. All events provided participants with opportunities to capture and share relevant knowledge and evidence and for the stakeholders to provide input and feedback on the research as it developed. Event design deliberately allowed time and space for the ARCC network community to grow, strengthening collaborative efforts and helping to enhance the overall quality and relevance of research outputs.
For the second phase of work (2014–2018), EPSRC recognised that the ARCC network had developed into a mature network and requested that the remit be expanded to include relevant research from across the EPSRC-funded portfolio (and beyond where appropriate). The core rationale of developing knowledge exchange and impact-focused opportunities and working with researchers to facilitate their engagement with policy and practice remained the same. But the challenge was to expand the approach to be responsive to the evidence needs of a much broader stakeholder community, whilst still being sufficiently engaged with a wide range of individual projects to help realise the provision, integration and uptake of useful information. This broadening also reflected the changing nature of the knowledge needed to address the evolving adaptation and resilience needs of stakeholders. For example, within the infrastructure and built environment sectors, many of the issues and responses are socio-technological in nature and, as such, engagement was broadened to include research on social and behavioural aspects of change, including but not restricted to climate change.
Across both phases of the ARCC network, a flexible approach responding to evolving knowledge and evidence being produced and required was essential. It was important to work across the network to clearly define the network's efforts, including identifying knowledge and evidence needs, working with researchers to consider relevant outputs, and targeting and facilitating knowledge exchange activities to enhance the uptake and use of salient research outputs. All activities were underpinned by an integrated approach to dissemination: a central website providing up-to-date information complemented by a monthly e-newsletter (>1000 recipients) and a popular Twitter feed with over 1000 followers. So what, now what? guides were introduced to facilitate the rapid sharing of the implications of new research findings, and a blog series enabled adaptation experts to share their thoughts.
The challenges associated with delivering the required researcher-stakeholder engagement and facilitating knowledge exchange requires specific expertise, skills and time. These should never be underestimated and having an effective core network team with a sufficient breadth in the required knowledge and skills, along with clarity in their respective objectives, roles and relationships is fundamental to success. We also found it critical to be able to seek independent advice and feedback, but also to be able to clarify and demonstrate the added value of the network. To these ends, the ARCC network made effective use of the ARCC Advisory Group (comprised of members of the relevant stakeholder community), targeted interactions with the research and the broader stakeholder communities, and a bespoke evaluation framework. This combination provided an appropriate and effective balance between the required versatility and rigour.
Innovative approaches to knowledge exchange were developed including the use of science-policy/practice dialogues (e.g. the overheating of buildings; understanding infrastructure interdependencies; exploring how people's senses can be affected by the design of public spaces) and targeting showcasing events at industry trade shows (e.g. UK Construction Week, Ecobuild). Working with relevant professional institutions (e.g. IET, CIBSE, ICE, CIRIA) and organisations (e.g. National Platform for the Built Environment, the EA Infrastructure Operators Adaptation Forum, Royal College of Physicians), was particularly valuable in enhancing the focus and reach of outputs across the membership of these organisations.
The ARCC network also worked extensively with early career researchers to help develop the skills needed to support the next generation of research leaders. A KE skills development training programme was developed, with eight workshops reaching over 150 researchers from 35 universities and covering topics such as proposal writing, effective stakeholder engagement, addressing pathways to impact, and showcasing research. And a series of Joint Working Opportunities funded six short placements for early career researchers to work within policy and practice to better understand the interface between research outputs and their use.
Looking to the future, we anticipate that new opportunities for the use of outputs from the network will continue to emerge, e.g. for topic-specific synthesised outputs on Ageing & mobility in the built environment, on Flooding & business, and on Enhancing the use of decision-support models. These and the other resources from the ARCC network will continue to be available through its website) to help inform policy and practice beyond the lifetime of the network. In addition, lessons learnt from coordinating this successful knowledge exchange network have been captured as a means of informing similar initiatives (pdf, 2.6 MB).
We also believe that there is an on-going need to take up the challenge of supporting and facilitating KE within the built environment and infrastructure sectors, particularly with respect to adaptation and resilience to change. These sectors present major challenges and opportunities for society's prosperity and well-being, both today and in the future. With the recognition that associated risks and responses require complex socio-technological considerations, the opportunity exists for a cross-research council funded network/s. The evidence needs and capacities of the research and stakeholder communities continue to evolve, as do approaches to effective KE. On-going support is valuable for established stakeholder-researcher relationships, and many of the newer relationships (particularly those reaching out to stimulate and inform action within the private and public sectors) would benefit from targeted KE and engagement to enhance the impact of research council investments.
With the support over the nine years from:
Victoria Hayman, Fiona Hewer, Kay Jenkinson, Anastasia Mylona, Phil Sivell, Briony Turner, Pete Walton, Tanya Wilkins and Stephanie Ferguson
ARCC blog
So what, now what guides
Helping researchers to enhance uptake & use of built environment models


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Trachymyrmex papulatus är en myrart som beskrevs av Santschi 1922. Trachymyrmex papulatus ingår i släktet Trachymyrmex och familjen myror. Inga underarter finns listade i Catalogue of Life.

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redpajama_set_name: RedPajamaWikipedia


We all know that business owners want to make their operation as efficient as possible. However, far too many people focus on the wrong areas of their firm. Believe it or not, you could improve your company by making small alterations to your web design. Sometimes streamlining your business doesn't mean you have to make changes to the way in which you operate. Making it easier for your customers and clients to spend their money also works well. The ideas below will help to improve the experience for people who spend money with your company. Even so, they'll also assist you in keeping more cash in the bank.
It's possible to use an automated text message service to make life easier for your customers. You can link your system to such a service and make sure they get reminder messages about their appointments or deliveries. That's handy for businesses that provide a service because clients should never miss their slots. However, it's also handy for companies that sell products. That's because they can let the customer know when the delivery driver will arrive. Ask your web design team to find a decent text messaging service and implement it as soon as possible.
Sometimes your customers are ready to purchase a product, but they have a few questions. Providing them with a customer service email addresses is okay, but you won't provide the answers quickly enough. Live chat software allows the customer to speak with a member of staff in only a few seconds. It means you can put their mind at ease before they leave the site. That should encourage them to continue with the purchase and spend money. Once they've left your site, you might struggle to get them to come back.
By linking your site to ordering and picking software, it's possible to make your life much easier. Whenever a customer places an order, it will go through the system to the right people. You can ensure it goes one the right delivery van for the location, and it could even print the postage labels. Ideally, anyone who wants to streamline their operation will need to remove as much human interaction as possible. Just do some research online to find the best software for companies in your industry. In most instances, it will also link with your stock control. That means you can place automatic orders with suppliers whenever you're running low.
As you can see, it's easy to boost productivity and efficiency when you have the right information at hand. We're living in the digital age, and so it doesn't make sense to avoid technology. You now know how much of a difference it could make to your operation. With a bit of luck, you'll increase turnover and make higher profits as soon as you implement the suggestions on this page. Always strive to stay at the forefront of your industry and beat competitors on all levels. That is how true entrepreneurs succeed.


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Home Featured Story Gov't working to regularize temporary staff of Data Protection Commission – Ursula
Gov't working to regularize temporary staff of Data Protection Commission – Ursula
Communications Minister-designate Ursula Owusu-Ekuful has revealed that the Data Protection Commission has been working with temporary staff due to financial constraints.
She however, said the government is working with the Commission to get the financial problems resolved to enable the Commission regularize the staff.
Mrs Owusu-Ekuful said these during her vetting by the Appointments Committee of Parliament on Monday February 15.
When asked by Haruna Iddrisu, Member of Parliament for Tamale South to explain the inability of the Commission to employ the temporary staff, she said "Many of the staff at the Data Protection Commission are temporary because of the funding challenges that they have currently. But we are working with them to resolve that."
The Ablekuma West lawmaker added "I have told them to also act in accordance with the law because they can't keep temporarily employing people for more than 6 months."
She further stated that "All data controllers who gather personal data of everybody is required to register with the Data Protection Unit. I am not sure even if parliament is registered with the Data protection unit but I will check.
"I will check that they will work with all data controllers to make sure that the data gathered is utilized and held in accordance with the law."
By Laud Nartey|3news.com|Ghana
READ ALSO: Akoma FM's blood donation attracts hundreds
Previous articleForward Ever, Walking Stick Never! The Significance & Symbolism of a National Monument
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Nuevo Living Greta swivel chair is notable for the seamless curvature of its design. Featuring an overstuffed wool form together with an exceptionally wide frame, the Greta offers remarkable comfort. An understated swivel base completes the contemporary silhouette blending refinement and grace.


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8 средно училище "Арсени Костенцев" в Благоевград, България е сред най-големите училища в града.

Обучават се ученици от 1 до 7 клас.

Адрес
 Благоевград, 2700
 ж.к. Еленово
 електронна поща: osmo@abv.bg

История
 1981 г. – откриване като основно училище. Разполага се в сградата на Строителния техникум.
 1990 г. – училището се премества в собствена сграда.
 1994 г. – преобразуване от основно в средно училище.
 2000 г. – започва профилирано обучение на ученици. Открива се паралелка с природоматематически профил след завършен осми клас.
 2002 г. – открива се паралелка с природоматематически профил след завършен седми клас.

Външни препратки
 8 СУ "Арсени Костенцев"

Средни училища в Благоевград
Основани в България през 1981 година


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Social media can be profoundly impactful for business, and many companies combine detailed strategies with a multitude of available platforms to their advantage on a daily basis. Others manage to fail miserably by falling into the trap of bad social media practice. Given the viral nature of the social landscape, it doesn't take long for a situation to escalate from one negative remark to a complete and total meltdown.
Take the case of Air Berlin and their failure to take responsibility for more than 200 bags that were left on the tarmac instead of being loaded onto one of their planes. Rather than helping its frustrated customers, the airline studiously ignored a continuing saga of social media comments that even included a Facebook group dedicated to the debacle. Attempts to contact the company were met with automated responses and contact numbers that yielded no help for days on end.
Ignoring customers online in the hopes that a problem will go away or fix itself is akin to staring at an oncoming train and believing you'll survive getting run over if you just hope hard enough. The longer you wait to respond, the more negative remarks will add up until you have a torrent of bad press that you can't erase.
The way you react to angry customers on Twitter, Facebook and other social platforms can make or break a situation as well. Shooting back angry comments in "retaliation" for negativity only makes you — and your business as a whole — look unprofessional. Insulting disgruntled customers, using swear words or trying to shift blame are all bad social media practices that will haunt your business for years to come.
To avoid digging yourself in deeper, keep in mind that everything you post on social media represents your business. You can't control the customer who decides they hate your product because it's not the right color or it doesn't have every bell and whistle under the sun, but you can control how you respond to their remarks. Be polite, be positive and make customer satisfaction your first priority to avoid the burn of social media fail.


Yiddish musicals never had much of a chance to become part of the Great American Songbook.
Like so many Jewish cultural developments, the medium was a victim of assimilation in the United States and tragedy in Europe. The works of the Gershwins and of Rodgers and Hammerstein supplanted Yiddish songs as English became the vernacular American Jews recognized as their lingua franca. The songs the Yiddish-speaking generation loved? Without an institution preserving the scores, librettos, and instrumentations, these musical treasures became the stuff of memory, never to be restored or restaged.
But in the midst of an unprecedented Yiddish musical revival, evidenced by the National Yiddish Theatre Folksbiene's "Fiddler on the Roof" opening Off-Broadway, the 104-year-old company's Global Yiddish Theatre Restoration Project is busy bringing these forgotten songs, shows and plays to an audience eager to rediscover them.
Folksbiene Artistic Director Zalmen Mlotek launched the project in 2015 with a revival of the 1923 Joseph Rumshinsky operetta "The Golden Bride." The production, which featured restored arrangements by Mlotek and Harvard musicologist Michael Ochs, received two Drama Desk nominations and played to 24,000 audience members. The show's reception got Mlotek and the Folksbiene's Associate Artistic Director Motl Didner wondering what else was out there, leading the pair to more productions, including a concert series of well-known and forgotten Yiddish standards. The process of curating and restoring these pieces is not an easy one.
Even when the conductor's score and a pit musician's specific parts are reunited into a cohesive whole, the work doesn't end there. Much of the material is handwritten and needs to be deciphered. Plus, there's the added wrinkle of whether the Yiddish was transliterated or written in Hebrew letters. In the latter case, there's much confusion as Hebrew reads right-to-left and music is read left-to-right.
The concert comprises over 15 numbers from musicals from the 1920s and '30s; some translations of show tunes written for WEVD radio, a Yiddish-language station owned and operated by the Jewish Daily Forward beginning in 1932; and many more songs originating from the movies of performer and lyricist Molly Picon. Didner and Mlotek watched many of the films, including 1938's "Mamele" and 1936's "Yitl Mitn Fidl," at the Center for Jewish Films at Brandeis and picked their favorites to restore and orchestrate. For the concert performance, the original film clip plays before ceding the stage to a live singer and full orchestra.
One such artist is Rachel Policar, who played the title role of Goldelle in 2015's "The Golden Bride." Like many of the Folksbiene's performers, Policar had never performed in Yiddish before that production and knew only a few stray words courtesy of her grandmother. The German she learned as an opera major helped, too.
Policar will be singing a Yiddish translation of Irving Berlin's 1950 duet "You're Just In Love" with Daniel Greenwood and the lullaby, "Unter Beymer," from the 1940 film "Der Vilna Shtot Khazan" among others at the March matinee at the Museum of Jewish Heritage.
The Museum's Safra Hall is the home base venue for the Folksbiene, having hosted their Yiddish "Fiddler on the Roof" prior to its move uptown. The Restoration Project last performed at the Hall with a workshop of its largest endeavor-to-date: A full remounting of Avrom Goldfaden's 1879 operetta "The Sorceress," a pivotal piece of the Yiddish canon first produced in New York by a 14-year-old Boris Thomashevsky, who would go on to become a star and impresario of the Second Avenue theater. The Folksbiene's full production of "The Sorceress," the first such staging in over 80 years, will premiere this December.
"It's the first one that we fully restored in-house," Didner said of the project, which was pieced together from documents at the YIVO Center for Jewish History in New York.
The orchestration Mlotek and Didner found there was part of the archives of the Vilna Paper Brigade, which preserved a cache of cultural documents from YIVO's precursor in Poland in 1942.
While the Folksbiene continues to commission new Yiddish work, Mlotik believes the sometimes-painstaking efforts of The Restoration Project constitute an essential part of the Folksbiene's mission in the 21st century.
"From the Yiddish Rialto to the Silver Screen," part of Carnegie Halls "Migrations" series plays at Safra Hall at the Museum of Jewish Heritage March 11 at 2 PM. More information and tickets can be found here.


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July-December 2021
Volume 5 | Issue 2
Online since Thursday, August 26, 2021
Dynamic immune status of pregnancy and dermatological diseases: An interplay p. 131
Navya Parthasarathy, Ajit B Janagond, Arun C Inamadar, Anusha Lingaiah, Meghana Gangadhar, Nazneen Zulfikar Arsiwala, Rintu Merin George, Vartika Ratan
DOI:10.4103/CDR.CDR_47_19
Dynamic changes of immune system in the various stages of pregnancy affect the course of various diseases afflicting the mother alongside determining how pregnancy affects these diseases. To understand this, a thorough knowledge on how the immune system differs in pregnancy is essential. The complex interplay between the maternal and fetal immune systems via placenta in order to maintain the pregnancy leads to waxing and waning of immune responses in both mother and fetus. This dynamic nature of immune responses can heavily influence the manifestations and severity of several dermatological diseases, whether infectious or noninfectious. Here, we discuss the effect of altered immunity of gestation on a few important dermatological diseases such as psoriasis, systemic lupus erythematosus, syphilis, varicella, leprosy, and TORCH infections and vice versa.
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COVID-19 vaccination in India: Clinical guidance for patients with dermatological diseases p. 139
Namitha Chathra, Savitha Somaiah
Since the advent of COVID-19 vaccines, dermatologists have frequently come across patients, especially those receiving immunomodulatory drugs, who express concerns about the safety and efficacy of vaccines. In this review, we aim to provide guidelines to dermatologists with regard to the three COVID-19 vaccines licensed for use in India. All dermatology patients, even the ones on immunomodulatory drugs, need to be encouraged to take the vaccine. COVID-19 vaccines are not contraindicated in individuals afflicted with eczema; atopic dermatitis; psoriasis; vitiligo; lichen planus; urticaria; connective tissue disorders; and bacterial, mycobacterial, viral, or fungal infections. However, those who have been seriously ill requiring hospitalization are advised to wait for 4–8 weeks. For patients on immunomodulatory drugs, when the disease is stable, the drug may be withheld or dosage reduced for 1–2 weeks following vaccination. However, the vaccination may be given without any modification in the drug/biological. People with a history of anaphylaxis/urticaria can receive a COVID-19 vaccine with 30 min postvaccination observation period. Absolute contraindications include a history of immediate hypersensitivity to any component of the vaccination and hypersensitivity following first dose of vaccination. Patients who have received vaccination can undergo procedures such as skin biopsy, cautery, cryotherapy, lasers, chemical peels, excisions, biopsy, and hair transplantation; fillers may be scheduled 2 weeks before or after the vaccination.
Importance of dermoscopy in differentiating common urticaria and urticarial vasculitis: A randomized control study p. 144
Mahajabeen Saheb Patel Madarkar
Background: Urticarial vasculitis is a clinicopathological entity that overlaps with common urticaria, and histopathological diagnosis is required for differentiation between them. Objectives: To determine, for the first time, if skin surface microscopy can aid in the clinical differentiation between common urticaria and urticarial vasculitis in daily practice. Materials and Methods: Lesions in 20 patients with a clinical diagnosis of urticaria were studied. All urticarial lesions were subjected to dermoscopy, skin biopsy, and histopathological examination to confirm the diagnosis. Dermoscopy was performed using Derm Lite 3 dermoscope and images captured were anyalysed. Clinical images were taken. A punch biopsy was performed in all patients. Statistical analysis was done. Results: In 11 patients diagnosed clinically as chronic urticaria, on dermoscopy showed red lines in 9(45%), red dots in 2 (10%) and structureless areas in 8(40%) patients. In 9 patients diagnosed as urticarial vasculitis clinically, on dermoscopy revealed purpuric dots in 8(40%) and purpuric globules in 5(25%) patients. Conclusion: We conclude that in our setting dermoscopy significantly facilitates the detection, diagnosis and differentiation of common urticaria and urticarial vasculitis.
Skin behind the bars! p. 149
Komal Ramteke, Sumit Kar, Safa Patrick, Ajinkya Sawant, Pooja Manwar, Pratiksha Sonkusale, Subhor Nandwani
DOI:10.4103/CDR.CDR_108_20
Background: Prisoners fall in the most vulnerable population group, but the health issue of this group is the most understudied. The various dermatological conditions that hamper their overall health and quality of life needs to be identified and serious measures should be undertaken for preventing them. Objectives: This study is one of the rare studies that aim to identify the dermatosis pattern and to relate with its etiological factors and suggest preventive methods to be undertaken for it. Materials and Methods: Total three visits were made to the district jail located in Central India over a period of 8 months, and the prison inmates were clinically examined. The data was recorded and results were drawn. Results: Scabies accounted for 31.51% while dermatophytes accounted for 30.83%. Other dermatoses seen were acne vulgaris (5.17%), allergic contact dermatitis (ACD) in 5.03%, pyoderma (2.71%), urticaria (2.86%), and tinea versicolor (2.62%). These were followed by the other dermatoses such as milia (1.81%), alopecia areata (0.5%), and irritant contact dermatitis (0.5%); viral infections such as herpes labialis (0.45%) and molluscum contagiosum (0.45%); and pigmentary disorders such as vitiligo (0.65%) and melasma (1.16%). Three new cases of Hansen's disease were diagnosed clinically (1.75%). Conclusion: We found that common dermatoses were scabies and fungal infections which are due to the overcrowding and poor hygiene facility in the prison premises. During the subsequent visits, the number of dermatophyte infections declined which may be attributed to patient counseling and awareness regarding hygiene and general cleanliness which was provided by us to the inmates in all previous visits. A detailed look into the matter may improve the overall dermatological health of the inmates.
A study on pattern of dermatoses affecting periorbital region and its clinicodermoscopic correlation p. 153
Namrata Bhavsar, Pragya Ashok Nair
Background: The periorbital area may be affected by a vast number of dermatoses such as infectious or noninfectious diseases, inflammatory dermatoses, systemic diseases, drug reactions, benign and malignant lesions, and traumatic lesions, thus poses both diagnostic and therapeutic challenge. Objectives: To study the pattern of dermatoses involving periorbital region and to correlate its clinical and dermoscopic findings. Materials and Methods: A cross-sectional study was carried out in patients with periorbital dermatoses (PODs) attending the Department of Dermatology during April 2018–March 2019 after approval from the ethical committee. A detailed history was taken and investigations including hemoglobin levels, Vitamin B12, serum cholesterol, and wood's lamp examination were done as and when required. A prestructured pro forma was used to collect the data. Data were entered into Microsoft Excel 2010 and analyzed using EPI INFO. Ver7 software (Developed by united states of America centre for disease control. Results: A total of 275 patients were studied of which majority of patients belonged to the age group of 41–60 years (38.5%) with a female-to-male ratio of 1.16:1. The most common group of PODs was skin tumors (25.1%), followed by disorders of pigmentation (17.4%), infections (13.1%), and periorbital dermatitis (11.6%). Most common dermoscopy findings of PODs were as follows: (a) common seborrhoeic keratosis (CSK): comedone-like opening, fissures and ridges, and sharp demarcation; (b) verruca vulgaris: finger-like papilla, red brown dots in center of papilla; (c) periorbital hyperpigmentation: blotches, globules, exaggerated pigment network, and reticular vessels; (d) allergic dermatitis: patchy red dots, pinkish hue, and patchy scale; (e) senile comedone: comedone-like opening; and (f) xeroderma pigmentosus: orange–yellow homogenous structures. Conclusion: Periorbital region is an area of cosmetic concern. Dermoscopy improves the differential diagnosis of common PODs and its knowledge may aid to reduce unnecessary invasive procedures such as shaving or incisional biopsies which may lead to scarring.
Clinicobacteriological study of pyoderma with trends in antibiotic sensitivity at a tertiary care center in western India p. 161
Kasturi Chavan, Bhavana Ravindra Doshi, Vaishali Dohe
Background: Pyoderma refers to any pus-forming infection of the skin. Antibiotic resistance has significantly downplayed the utility of established antibiotics and possesses a serious threat to public health. Objective: To study the causative organisms, their trends of antibiotic sensitivity pattern thus helping in prescribing appropriate antibiotics and study the response to the treatment in patients of pyoderma. Materials and Methods: A 2-month prospective study on a cohort of 30 pyoderma patients attending the outpatient and inpatient department in our tertiary care hospital under ICMR short-term studentship was undertaken. Statistical analysis was performed using the SPSS software version 24. Results: Those in 5th–6th decade were more predisposed. Higher incidence was seen in anemics. Staphylococcus spp. (26/30 case 86.66%) was the most common organisms to be isolated in 12/15 (80%) outpatients and 14/15 (93.33%) inpatients. Methicillin-resistant Staphylococcus aureus (MRSA) was isolated equally (33.33%) in both outpatient and inpatients, with increasing trend in MRSA in out-patients. Higher incidence of Pseudomonas aeruginosa in outpatients was noted. MRSA in superficial pyoderma group was sensitive to one first-line drug which was gentamycin, whereas in deep pyoderma, the only first-line drug to which the MRSA was 100% sensitive was ciprofloxacin. All MRSA, MSSA, MR CONS, and MS CONS were sensitive to all second-line drugs. Sixty-percent patients who showed no response to empirical primary line of treatment showed good response on changing the antibiotics according to the reports of culture and sensitivity. Conclusion: An increasing trend in MRSA in outpatients was noticed along with higher incidence of Pseudomonas infection. Limitation: Small sample size.
A descriptive case-control study on assessment of iron profile in patients with and without melasma p. 168
Megha Prakash, Namrata C Manjunath, BS Deepali
Background: Melasma or chloasma is a common acquired hyper melanosis, characterized by dark, irregular hyperpigmented macules and patches over the malar areas, lips, nose and forehead. Iron overload manifests with skin hyperpigmentation. Therefore, it is important to understand the role of iron in patients with melasma. Objectives: (1) To assess serum iron profile in non-pregnant women and men with melasma. (2) To assess the same parameters in age and sex matched controls. Materials and Methods: A descriptive case–control study with 35 cases of melasma and 35 age and sex-matched controls was conducted between December 2019 and March 2020, to assess the association between melasma and iron deficiency. Results: Among 35 cases of melasma, 85.7% were females, the most common type was the malar type 68.8%, sunlight was the most-common risk factor and 100% had deranged iron profile. Mean ferritin levels in the melasma group was 15.204 ng/ml while in control group it was 71.717 ng/ml. Mean serum iron levels in melasma group was 28.585 μg/dl while in that of controls were 135.018 μg/dl. Other iron parameters also showed significant iron deficiency in melasma patients. Conclusion: Well-known factors implicated in the etiology of melasma include sunlight, Oral contraceptive pills with oestrogen, pregnancy and smoking. This study indicates that iron deficiency is also an important etiological factor and hence treatment of iron deficiency may be a novel therapeutic approach in patients with refractory melasma.
A study of cutaneous adverse drug reactions in a tertiary care center in south India p. 173
Lakshmi Rajendran, Anoop Thyvalappil, Rajiv Sridharan, S Ajayakumar, EM Sparshadeep, Binoo Divakaran
Background: Cutaneous adverse drug reactions (CADRs) are common among adverse drug reactions (ADRs). Early identification of ADRs can reduce the morbidity and mortality rates. Objectives: To know the pattern of various types of CADRs and to find out the causative drugs involved. Materials and Methods: Retrospective analysis was performed from ADR register, kept in Dermatology department in a tertiary care center. Naranjo's algorithm was used to determine the causality assessment. Details regarding drug intake, morphology of eruption, offending drugs, history regarding hospitalization, drug rechallenge or drug dose modifications, and treatment given to the patients were assessed. The data were subjected to descriptive analysis. Results: A total of 216 patients were recruited into the study, of which 118 were male and 98 were female. Antimicrobials (30.1%) were noted to be the most common offending drugs, followed by antiepileptics (18.1%), analgesics and antipyretics (11.1%), and anticancer drugs (11.1%). The most common presentation of CADR was maculopapular drug eruption (31.5%), followed by fixed drug eruption (13.4%). Conclusion: Among the antimicrobials, penicillins (13.9%) were the most common cause of CADR, followed by cephalosporins (8.8%) and fluoroquinolones (6.9%). A total of 28 patients (13%) were found to have severe cutaneous adverse reactions to drugs. It is important to closely monitor the patient, when a new drug is introduced, which will aid in detecting and preventing of CADRs.
Stressful major life events and chronic urticaria: Its role in induction or exacerbation of the disease p. 178
Preeti Ganesh Choudhari, Ganesh Kamath Hundi, D Sukumar
Background: The skin and central nervous system are derivatives of embryonic ectoderm. There is an etiological factor of stressful life events in various skin diseases such as chronic urticaria through psychosomatic mechanisms. Many observations and case series are reported in favor of this opinion. Objectives: To evaluate the stressful life events within one year, six months and a month preceding onset or exacerbation of lesions in chronic idiopathic urticaria cases enrolled in this study. Material and Methods: It is an Observational descriptive questionnaire-based study, which included minimum of 50 patients of chronic idiopathic urticaria and important stressful events were noted in these subjects using Gurmeet Singh's presumptive stressful life events (PSLE) scale. Results: Out of 50 cases, stressful life events preceded the exacerbation of the chronic urticaria in 16 (32%) patients. Amongst them 12 (24%) showed slight degree and four (8%) showed moderate degree of stress and none of the cases reported great degree of stress. Among 16 cases, eight (50%) cases noticed exacerbation within six months of experiencing stressful life event with higher degree of severity in older age group (p = 0.004). Financial loss or problem was the most common stressful life event seen in four out of 16 cases (25%) (p = 0.000). Few desirable events were also found as stressors in four cases accounting for 25%. Conclusion: These results support association between psychological factors and exacerbation of the disease. The need for stress management programs in high stress scores to cope up with the stressful events, will further help in reducing the morbidity.
Apremilast titration: Real-world indian experience p. 183
Abhishek De, Aarti Sarda, Dhiraj Dhoot, Hanmant Barkate
Background: Apremilast is recommended to titrate in initial period to reduce adverse effects (AE). But inspite of that, in India; many dermatologists experienced a lot of AE resulting in discontinuation of therapy. As a result, many of them have adapted to titrate the dose in different ways. Objectives: To evaluate the AE profile and rate of discontinuation of apremilast during initial titration in different ways. Materials and Methods: A multicentre, retrospective data analysis was done at 121 dermatology clinics across India in the adult patients diagnosed with chronic plaque psoriasis and prescribed at least one dose of apremilast. Patient characteristics and data were obtained from medical records when available. Results: Out of 582 patients, 175 were prescribed apremilast starter pack in licensed dose (Group 1); 202 were prescribed starter pack in OD dosing (Group 2) for 13 days and 205 were prescribed 2 starter packs in OD dosing (Group 3) for 26 days. 45.14% had AE in Group 1 whereas 36.63% and 30.24% had in Group 2 & 3 respectively. Gastrointestinal upset, headache & nausea were most common. In Group 1, 17.71% of patients discontinued apremilast whereas 16.33% and 10.24% discontinued in Group 2 & 3 respectively. On comparison within group, Group 3 had significant difference over Group 1 (p value <0.05). Conclusion: It is concluded that slower titration of apremilast in initial phase leads to lesser AE profile and hence discontinuation of therapy and thus increasing adherence.
Impact of COVID-19 on Dermatology practice: A cross-sectional study p. 187
Ajit B Janagond, Vartika R Ratan, Indira Potthuri, Vishalakshi S Pandit, Arun C Inamadar
Background: The sudden outbreak of novel coronavirus has caused confusion, anxiety, and fear not only among the general public but also the health-care system. Considering widespread effects of the disease spilling into all aspects of life in general population and health-care workers alike, we conducted a study regarding the impact of coronavirus disease 2019 (COVID-19) on the functioning of the department of dermatology at a tertiary care hospital during the period of lockdown. Objective: We aimed to study the impact of COVID-19 infection and lockdown due to pandemic on practice of dermatology and workings in the outpatient department (OPD) at a tertiary care center. Materials and Methods: A cross-sectional, observational study was conducted on patients attending the dermatology OPD at a tertiary care center from April 11, 2020, to May 31, 2020. Patients were interviewed on the basis of a simple questionnaire seeking demographic details, complaints, diagnosis, history, and duration of treatment. Data obtained were recorded as numbers and percentages. Results: A total of 1022 individuals participated in the study with 620 (60.6%) males and 402 (39.33%) females. Among them, 625 (61.15%) were localities and 395 (38.64%) were from surrounding rural areas. The age of patients ranged from 6 months to 94 years, and majority were farmers. Eight hundred and twenty-nine (81.1%) were educated and 146 (14.2%) were illiterates. Six hundred and ninety-seven (68.1%) of the participants were new and 325 (31.8%) follow-up cases. Dermatophytosis 194 (27.8%) and psoriasis 15 (4.6%) were the most common diagnoses among new and old cases, respectively. Conclusion: A significant reduction was observed in the number of patients visiting the department seeking treatment. The pandemic necessitated various modifications in the patient examination and management protocols.
Staphylococcal-Scalded skin syndrome: A case series p. 192
Anirudha Gulanikar, Arpita Arghya
DOI:10.4103/CDR.CDR_4_20
Staphylococcal-scalded skin syndrome (SSSS) is also known as Ritter's disease. The symptoms produced by the strains of staphylococcus occur due to exfoliative toxins. Here, we have presented a case series of four children aged <2 years, who were admitted in MGM Medical College and Hospital, Aurangabad, for fever in association with superficial fluid-filled lesions leaving large denuded areas behind Nikolsky's sign – positive. The mucosal area was spared. Blood culture served as diagnostic test, besides clinical history and examination. All the children were treated with cephalosporin and responded well. Hydration was maintained with topical mupirocin over the eroded areas. A high degree of suspicion has to be there for SSSS. We emphasize the importance of interdisciplinary management, association with dermatologist, pediatrics, and plastic surgeon for better outcome. Although considered rare, we came across four cases of SSSS with classical presentation.
Morphoeic basal cell carcinoma – an unusual tumor variant at an unusual site p. 197
C Chandrakala, GK Tharini
Basal cell carcinomas (BCC) are malignant neoplasm arising from the basal layer of epidermis, seen almost exclusively on hair-bearing areas of skin. There are many clinical and histopathological variants in BCC. The tumor commonly seen at the site of excessive sun exposure. It is a locally invasive tumor with rare metastasis. The most common site for the development of morphoeic BCC is over the face. Clinically, morphoeic BCC presents as morphea such as sclerotic plaque and histopathologically as densely hyalinized stroma with angulated strands of neoplastic basaloid cells. Ulceration of the lesion is uncommon in this type. We report a case of morphoeic BCC, an unusual tumor variant occurring over the back.
Alkaptonuria: A hereditary disease which is usually diagnosed in adulthood p. 200
Mudita Gupta, Rajni Sharma, Ritu Rani
Alkaptonuria (AKU) is a multisystemic autosomal recessive disease due to deficiency of enzyme homogentisate dioxygenase leading to accumulation of homogentisic acid. Urine becoming dark on oxygenation or alkalinization is the first symptom but is often ignored. The patient usually presents with pigment deposition in connective tissue and cartilage after the third decade. This pigment deposition not only alters the aesthetics but also leads to alteration in the activity of different tissues due to inflammation and subsequent fibrosis or calcification. We are presenting an adult male who was asymptomatic till 5 years back when he started having backache for which he was taking analgesics off and was diagnosed to be having AKU at the age of 58 years.
Giant cutaneous epithelioid angiomatous nodule: A rare vascular tumor p. 204
Jayati Shailesh Dave, Atul M Dongre, Sunanda Arun Mahajan, Uday S Khopkar
Cutaneous epithelioid angiomatous nodule (CEAN) is an uncommon benign vascular proliferation that presents as a reddish solitary nodule. Less than 60 cases have been reported in the literature. As it is benign, the prognosis is good, but it is sometimes difficult to differentiate it from other vascular neoplasms. A 16-year-old male presented with a single, large, brownish multinodular swelling over the left pinna. Biopsy showed conglomeration of epithelioid endothelial cells with eosinophilic cytoplasm in the dermis. These cells stained positive for CD31 and CD34. Diagnosis of CEAN was made
A female with mucocutaneous telangiectases and portal hypertension: A case report of osler-weber-rendu syndrome p. 207
Vidhi S Chandibhamar, Bhagirath R Patel, Ani Patel, Jignaben K Padhiyar
Osler-Weber-Rendu syndrome, also known as hereditary hemorrhagic telangiectasia, is a rare autosomal dominant disorder manifested by telangiectases of the skin and mucous membranes and arteriovenous malformations of various organ systems. We report a case of 45-year-old postmenopausal woman who presented to dermatology department for evaluation of compressible vascular lesion involving bilateral palms and oral cavity for the past 3 months' duration. On further evaluation, she was found to have portal hypertension and multiple cavernoma formation on place of portal vein.
Single plaque lepromatous leprosy presenting as granuloma annulare: A rare presentation p. 210
Sudha Rani Chintagunta, Priyanka Jaju
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, primarily affecting the peripheral nerves and skin. The clinical presentation of leprosy is highly variable, depending on the immune status of the individual. Based on the Ridley–Jopling classification, the clinical spectrum ranges from tuberculoid to lepromatous leprosy (LL). In all its stages, it can mimic various other conditions. Early and accurate diagnosis of leprosy is crucial because late recognition may give rise to permanent deformity resulting from the disease. Here, we report a case of LL clinically presenting as granuloma annulare in a 75-year-old man, which was diagnosed and confirmed by histopathology.
A case series of disseminated porokeratosis p. 213
J Logeshwari, Nippa Devi A Patel, Sirisha Varala, Ananthula Venkata Krishna
Porokeratosis is an autosomal dominant disorder of epidermal keratinization resulting from abnormal expansion of latent clones following chronic ultraviolet exposure or immunosuppression. Various clinical and morphological variants of porokeratosis are present, among which disseminated superficial actinic porokeratosis (DSAP) is the most common subtype located predominantly on the sun exposed areas, whereas disseminated superficial porokeratosis (DSP) is present both on the sun exposed and sun protected areas including oral mucosa and genitalia. Porokeratosis is characterized clinically by annular plaques with atrophic center and thready border and histologically by the presence of cornoid lamella. DSAP may be missed because of its inconspicuous nature in dark skinned individuals and may sometimes be mistaken for actinic keratoses in sun-damaged skin. Here, we report a case series of five patients with disseminated porokeratosis with varied presentations.
An interesting case of synchronous basal cell carcinoma of face successfully treated by surgery p. 217
Sucheta Pathania, Navneet Sharma, Tashi Dolma Bodh
Basal cell carcinoma (BCC) is the most common type of nonmelanocytic tumor. Multiple BCCs are generally associated with heredo-familial conditions or syndromes, but in sporadic cases, multiple BCCs are relatively rare. They tend to occur in synchronous or metachronous manner, but in our setup, synchronicity is uncommon and metachronous BCCs are attributed mainly to reoccurrence. We present a case of dual BCC of face with synchronicity and different histopathology, treated with wide local excision using full-thickness grafting and V-Y advancement flap.
Giant subcutaneous granuloma annulare p. 220
MR Harish, BM Shashikumar, Priyanka R Magod, Deepadarshan K Gowda
Subcutaneous granuloma annulare is an uncommon, benign self-limiting cutaneous disease, almost exclusively seen in young children. We report a case of 31-year-old male patient, presented with asymptomatic firm plaques over the left lateral malleoli and dorsum of the feet. Histopathological examination was done to confirm the diagnosis and the lesions responded well to monthly doses of the combination of rifampicin, ofloxacin, minocycline (ROM) therapy and intralesional steroid therapy. This case is reported for its unusual presentation of very large plaque in an adult male and its resolution after combined ROM and intralesional steroid therapy.
Intriguing case of porokeratosis of mibelli on gluteal region p. 223
Snehal Balvant Lunge, Vijayalakshmi M Dhorigol, Anisha P Bindagi
Porokeratosis (PK) is a rare group of heterogeneous disorders of keratinization representing diverse phenotypic expressions of the same genetic defect, which is mainly inherited in an autosomal dominant manner. This report describes the case of a 40-year-old female with PK over the gluteal region. The rarity of this disorder, unusual site of presentation, and involvement of unilateral side of gluteal region, which is unusual in this form of PK, and the occurrence in a female patient motivated to report this case.
Pemphigus and beyond p. 226
Shital Poojary, Kavya Baddireddy
A 23-year-old male diagnosed with pemphigus foliaceous presented with multiple asymptomatic hyperpigmented patches and plaques clinically resembling seborrheic keratoses over multiple sites on the body of 1-year duration. There were no fluid-filled lesions, active erosions, or mucosal involvement. Histopathological examination from the hyperpigmented plaque revealed marked acanthosis with intra-epidermal acantholysis. Enzyme linked immunosorbent assay (ELISA) for antidesmoglein-1 antibodies was positive with a titer of 157 units/ml. Treatment with oral azathioprine, dapsone, and topical halobetasol propionate produced a marked response with complete clearance of the lesions. A thorough workup helped us detect the persistence of disease activity and thus prevent a potential relapse. This case report highlights the unusual presentation of a common immunobullous disorder, Pemphigus acanthomata a rare entity with regard to its morphological, histopathological, and immunological features.
Pleomorphic xanthomas: A clue to rare familial hypercholesterolemia p. 229
Shivangi Singh, Pankaj Kumar Tiwary, Anupama Singh
Xanthomas are the subcutaneous lipid deposits which can be seen in normolipedemic or hyperlipidemic conditions. Xanathomas are usually of single type and presence of polymorphic xanthomas arise suspicion of dyslipidemia. We report a case of young girl presenting with pleomorphic xanthomas (Xanthelasma palpebrarum, intertriginous Xanthomas, tendon Xanthomas, and eruptive xanthomas), hypothyroidism and multiple cardiac valvular involvements with very high serum total cholesterol and low-density lipoprotein along with deranged lipid profile in both parents. Pleomorphic xanthoma arouses a suspicion and helped in making a diagnosis of rare homozygous familial hypercholesterolemia.
Blueberry look-alike masson's hemangioma over the thigh p. 233
Yashaswi Rai, AS Savitha, TS Nagesh, Swathy Prasannan, Sneha Manjunath, Tarun Deepak Reddy
Masson's hemangioma (MH), also known as intravascular papillary endothelial hyperplasia, is a rare benign vascular tumor. Histopathology helps to confirm the diagnosis, wherein a papillary proliferation of thin-walled capillaries is almost always associated with thrombus formation in the lumen of a vessel. We report the case of a 48-year-old female with a purple-colored swelling over the right thigh that was diagnosed as MH with the help of histopathological examination. Dermoscopy was also done, and the findings were reported.
"What lies beneath" – macrophage activation syndrome unveiled systemic lupus erythematosus p. 236
JP Prathibha, Vivek Pai, P Ishwara Bhat
Macrophage activation syndrome (MAS) is a potentially fatal condition characterized by massive systemic inflammatory response in the setting of a myriad of systemic disorders such as autoimmune collagen vascular disease, infections, drug-induced, and malignancies. It falls under a group of disorders known as hemophagocytic lymphohistiocytosis of which familial and acquired types have been described. Here, we report a case of acquired MAS secondary to acute systemic lupus erythematosus (SLE). Early diagnosis and timely intervention resulted in a favorable outcome.
Multiple itchy nodules over the scalp – clinicopathological challenge p. 240
Aditi Dhanta, Gargi Taneja, Neirita Hazarika, Michael Leonald Anthony
Angiolymphoid hyperplasia with eosinophilia is an uncommon benign vascular proliferation with histologically distinct endothelial cells and a mixed inflammatory infiltrate composed of mainly lymphocytes and eosinophils unknown. It commonly affects middle-aged adults and characterized by flesh/plum-colored pruritic nodules and papules. In our case, it has to be differentiated from other appendageal tumors such as cylindroma, spiradenoma because of similar site involvement. The histopathological examination is a fundamental tool to achieve a correct diagnosis.
Giant venous malformation of the tongue with macroglossia: A hidden menace p. 242
Reena Kumari Sharma, Archita Makharia, Mudita Gupta, Suresh Thakur
Venous malformations (VMs) are congenital slow flow vascular malformations that are usually present at birth. They grow proportionate with the age and do not regress with time differentiating them from hemangiomas. VM presents as bluish discoloration of skin/mucosa or as soft subcutaneous masses. It may affect any organ, including viscera-like gastrointestinal tract or brain. VM is generally slowly progressive and asymptomatic as they grow slowly with age. We report the case of asymptomatic giant VM over the tongue for which the patient presented due to herpetic stomatitis.
Cobblestone appearances in dermatology p. 245
Anup Kumar Tiwary, Piyush Kumar
Dermatology is a visual medical discipline which demands watchful eyes, profound knowledge of different morphologic patterns of various dermatoses, and extensive clinical experience. A meticulous cutaneous examination always helps in generating the close differential diagnoses and incorporation of past visual experience leads to a provisional diagnosis, obviating the need of further investigations in many cases. Although there is a wide spectrum of morphologic presentations, some dermatoses may have characteristic appearances such as cobblestoning, Peau d' orange, umbilication, and Christmas-tree pattern. Identification of these lesional characteristics or patterns can efficiently avoid the misdiagnosis and unnecessary diagnostic workup. In this article, skin diseases showing cobblestone appearances on both clinical and dermoscopic examination have been compiled and outlined in brief.
DIAGNOSTIC PEARL
Diagnostic perplexity in hypertrophic lichen planus: Dermoscopy saves the day! p. 251
Samipa S Mukherjee, Balachandra S Ankad, SV Smitha, Balakrishna P Nikam
[HTML Full text] [PDF] [Mobile Full text] [EPub] [Sword Plugin for Repository]Beta
Acral lentiginous melanoma: Dermoscopic perspective in skin of color p. 253
Balachandra S Ankad, SV Smitha, Balakrishna P Nikam
Recurrent Apocrine Hidrocystoma of Scalp: A Rare Case Report p. 255
Hemant Kumar Sharma
Dermoscopy of cutaneous lymphangioma circumscriptum: A report of three cases p. 257
Yasmeen Jabeen Bhat, Atiya Yaseen, Sheema Sheikh
Co-localization of verruca vulgaris with verrucous epidermal nevus: Role of dermoscopy in diagnosis p. 260
Yasmeen Jabeen Bhat, Sumaya Zeerak, Reeta Devi, Iffat Hassan Shah
Retraction: Efficacy and safety of 88% phenol application versus cryotherapy in repigmentation of idiopathic guttate hypomelanosis: A prospective study p. 263
DOI:10.4103/2542-551X.324588


text:
Amazon Primed! Suffolk Downs, Revere push hard…
Amazon Primed! Suffolk Downs, Revere push hard in bid for new headquarters
(042905, Revere MA) Suffolk Downs prepares for tomorrow's opening day. Staff Photo by Faith Ninivaggi}.
(07/09/2017- Boston, MA) Old Glory flies over a sport that's glory days seem to be behind it at a day of racing at Suffolk Downs on Sunday, July 9, 2017. Staff Photo by Matt West
(07/09/2017- Boston, MA) Lagreats, right, cruises to victory in the 8th race at a day of racing at Suffolk Downs on Sunday, July 9, 2017. Staff Photo by Matt West
(07/09/2017- Boston, MA) Spectators watch the 4th race start out of the gates at a day of racing at Suffolk Downs on Sunday, July 9, 2017. Staff Photo by Matt West
By Bob McGovern |
PUBLISHED: September 26, 2017 at 12:00 am | UPDATED: November 17, 2018 at 12:00 am
The heavyweight developer that bought Suffolk Downs is ready to "swing for the fences" to convince Amazon.com Inc. to put its second headquarters on the massive plot of land that spans Revere and Boston.
"We think the site works, and we think it has a lot of what Amazon has said it's looking for," said Thomas O'Brien, managing director of the Boston-based Hym Investment Group. "Suffolk Downs fits all the factors Amazon is looking for."
O'Brien discussed making a pitch to Amazon after a Revere City Council Economic Development Sub-Committee meeting yesterday. He said his team is working quickly to get a proposal to the e-commerce giant, which announced that its requests for proposals are due Oct. 19.
"Where it's situated is a perfect location," O'Brien said of the longtime racetrack, adding that its position between two MBTA stops — Beachmont and Suffolk Downs — and its proximity to Logan International Airport make it a potentially enticing spot for the company.
Amazon's plan calls for as many as 50,000 full-time employees with an average annual compensation of $100,000 at its second headquarters. The Seattle-based company expects to grow into the space during the course of 10 to 15 years, according to its request for proposals.
Mayor Martin J. Walsh came out publicly in support of bringing Amazon to the city earlier this month, but last night he declined to comment on the Suffolk Downs proposal through a spokeswoman.
Revere city councilors reacted positively to O'Brien's proposal for the land but initially avoided mentioning Amazon by name during the introductory meeting, calling it the "big commercial tenant." But then committee Chairman Patrick M. Keefe Jr. called Amazon the "1A plan" for the land.
"It has all the amenities you need. It has the workforce from Boston and Revere, and I can't see why they wouldn't want to jump on this opportunity," he told the Herald. "For a city like Revere, it would be a total game-changer."
O'Brien told councilors that his team was "swinging for the fences" with the big-name proposal.
In an overview of potential plans to councilors, O'Brien indicated that the revamped Suffolk Downs would be a walkable, mixed-use development with neighborhood retail and open space. When likened to Somerville's Assembly Row, O'Brien said: "I think we can do a better job. We're competitive in that respect."
Amazon has said once it picks a location, the first phase of building will require more than 500,000 square feet that will be ready in 2019.
"We can hit that schedule," O'Brien said. "It's already zoned for that, and we can produce a campus for them that would accommodate their needs and it would also have great retail and places for workers to live. It would be a real mixed-use campus."
O'Brien added, "They want something that's integrated in the neighborhood. That's something you see here. Our sense is that's something Amazon wants. They aren't looking for a separate fortress."
Bob McGovern


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text:
Benzododeciniumbromid (systematický název dimethyldodecylbenzylamoniumbromid) je kvartérní amoniová sloučenina používaná jako antiseptikum a dezinficiens (fenolový koeficient 20-30). Benzododeciniumbromid je velmi dobře rozpustný ve vodě, má vlastnosti kationového tenzidu.

Je účinný především proti grampozitivním mikrobům. V nižších koncentracích je účinek proti podmíněně gramnegativním mikroorganismům (Proteus, Preudomona, Clostridium tetani atd.) nejistý. Neúčinkuje proti Mycobacterium tuberculosis a sporám bakterií. Delším působením inaktivuje některé viry.

Benzododeciniumbromid je součástí antiseptických přípravků značky Ajatin, vyráběných v České republice. Místo bromidu lze benzododeciniový kation používat též jako chlorid nebo jinou sůl.

Reference

Kvartérní amoniové sloučeniny
Dezinfekční látky
Antiseptika
ATC D08AJ


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