text:
Home / Persoonia - Molecular Phylogeny and Evolution of Fungi, Volume 40, June 2018
New Ceratocystis species associated with rapid death of Metrosideros polymorpha in Hawai`i
Authors: Barnes, I.; Fourie, A.; Wingfield, M.J.; Harrington, T.C.; McNew, D.L.; Sugiyama, L.S.; Luiz, B.C.; Heller, W.P.; Keith, L.M.
Source: Persoonia - Molecular Phylogeny and Evolution of Fungi, Volume 40, June 2018, pp. 154-181(28)
Publisher: Naturalis Biodiversity Center
DOI: https://doi.org/10.3767/persoonia.2018.40.07
The native `ōhi`a lehua (Metrosideros polymorpha) has cultural, biological and ecological significance to Hawai`i, but it is seriously threatened by a disease commonly referred to as rapid `ōhi`a death (ROD). Preliminary investigations showed that a Ceratocystis species similar to C. fimbriata s.lat. was the cause of the disease. In this study, we used a combination of the phylogenetic, morphological and biological species concepts, as well as pathogenicity tests and microsatellite analyses, to characterise isolates collected from diseased `ōhi`a trees across Hawai`i Island. Two distinct lineages, representing new species of Ceratocystis, were evident based on multigene phylogenetic analyses. These are described here as C. lukuohia and C. huliohia. Ceratocystis lukuohia forms part of the Latin American clade (LAC) and was most closely associated with isolates from Syngonium and Xanthosoma from the Caribbean and elsewhere, including Hawai`i, and C. platani, which is native to eastern USA. Ceratocystis huliohia resides in the Asian-Australian clade (AAC) and is most closely related to C. uchidae, C. changhui and C. cercfabiensis, which are thought to be native to Asia. Morphology and interfertility tests support the delineation of these two new species and pathogenicity tests show that both species are aggressive pathogens on seedlings of M. polymorpha. Characterisation of isolates using microsatellite markers suggest that both species are clonal and likely represent recently-introduced strains. Intensive research is underway to develop rapid screening protocols for early detection of the pathogens and management strategies in an attempt to prevent the spread of the pathogens to the other islands of Hawai`i, which are currently disease free.
52 References.
Keywords: CERATOCYSTIDACEAE; FUNGAL BARCODING GENES; INVASIVE SPECIES; ITS TYPES; NEW TAXA
This article was made available online on March 27, 2018 as a Fast Track article with title: "New Ceratocystis species associated with rapid death of Metrosideros polymorpha in Hawai`i".
Persoonia aims to publish papers dealing with molecular phylogeny and evolution of fungi. A further aim is to promote fungal taxonomy by employing a polythetic approach to clarify the true phylogeny and relationships within the kingdom Fungi. The journal publishes high-quality papers elucidating known and novel fungal taxa at the DNA level, and also strives to present novel insights into evolutionary processes and relationships. Papers to be considered include research articles and reviews.
Papers are published using a Fast Track system. This implies that the papers are immediately published online and freely available through the internet via this website. Volumes appear twice a year (June and December). From Volume 36 onwards (2016) hard copy volumes will only be made available through printing-on-demand. The issues can be ordered separately through the Publication Division of Naturalis Biodiversity Center; e-mail: [email protected]
Persoonia is a journal published jointly by the Naturalis Biodiversity Center and the Westerdijk Fungal Biodiversity Institute.
Back issues for Persoonia
Persoonia Supplement Series


These requirements would be phased in over 2 years after publication of a final rule.
The expected costs of implementing the proposed rule.
Click here to view the original notice published in the Federal Register. Click here to view the notice of the comment period extension. The extended comment period for the NPRM closes October 24.
In August, NADO joined the Association of Metropolitan Planning Organizations (AMPO) and the National Association of Regional Councils (NARC) in submitting comments expressing concerns about the NPRM. Click here to view the comments.


My Space My Thoughts: Merry KissMas!
Tis's the season to be jolly!
Hope everyone had fun and enjoyed yourself totally.
This Christmas I spent it a little differently from the usual ones.
By all means, judge me!
After having your own crib, the idea of staying at home just comes naturally.
Some of the Christmas Lightnings that we snapped!
I have picked the lucky winner of the Dior Inspired Double Pearl Earrings.
Immerse yourself in the Chrismassy Mood!


Power is one of the most critical components of infrastructure and crucial for the development of nations. Electricity demand in the country has increased rapidly and is expected to rise further in the years to come. In order to meet the increasing demand for electricity in the country, massive addition to the installed generating capacity is required.
Keeping in view the future demand of energy, the State run agency Himachal Pradesh Government Energy Development Agency (HIMURJA) is implementing the Renewable Energy Programme in the State. The Renewable Energy Programme is aiming to create awareness and to demonstrate effective and innovative use of Solar Photovoltaic Systems for the individuals, community, institutions and industrial establishments.
The Central financial assistance is available under the Renewable Energy Programme on the Solar Photovoltaic Systems such as Solar Street Lighting Systems, Solar Home Lighting System and Solar Power Plants. The proposals received from the panchayats, institutions and government departments are forwarded to the Centre, for approval of subsidy. Apart from providing support for the installation of Solar Photovoltaic Power Plants, subsidy upto 90 per cent of the bench mark cost for plants is being provided for units being installed in Government buildings. Subsidy upto70 per cent is being provided to residential and social sector.
Till date, the Government has sanctioned 200 kW SPV Power Plant at Baru Sahib, 6.5 Kw Power Plant for H.P. Secretariat , 12 SPV Power Plants of 4 kWp capacity each in the District Collectorates and 20 kW SPV Power Plant at H.P. Vidhan Sabha, Shimla. Similarly, 10 Kw SPV Power Plant for Ranser Island, 10 Kw Power Plant for Kibber, 2 kW each SPV Power Plant in 216 Nos of Police Stations in the State, 450 kW aggregate capacity SPV Power Plants for IPH, District Kangra, 55 Kw aggregate capacity SPV Power Plant at Ridge Maidan, Old Bus Stand and Panchayat Bhawanin Shimla and 25Kw SPV Power Plant at Raj Bhawan Shimla stand installed.
As many as 250 SPV Power Plant of 1 kW capacity each have been sanctioned for individual households in the State, out of which 152 SPV Power Plants have been installed and remaining would be installed soon. 100 KW SPV Power Plant has been installed at HP High Court, 100 KW SPV Power Plant at HP Secretariat, 100 KW SPV Power Plant at HIPA and 50 KW SPV Power Plant have been installed at HP University, Shimla.
HIMURJA has installed 5 kWp at Bachat Bhawan, Reckong-Peo, 5 kWp plants each at ADC Kaza, BSNL Tower Mane Gomga Village, 43 rd BN, ITBP, Sugar Point, Spiti Valley, ITBP Sumdo, Spiti Valley and ITI Solan. 10 kWp has been installed at ITBP Mormi Dogri, Spiti Valley. 2 kWp plants have been installed at ITBP Kaurik, Spiti Valley, ITBP Baryog, Spiti Valley and ITBP Lepcha, Spiti Valley. One 3kWp plant has been installed at IPH Kaza, Spiti Valley.
Apart from these 3 SPV Power Plant of 100 kWp capacity at H.P. Judicial Academy, Gandal, Shimla, 14 SPV Power Plants of 1kWp capacity each of IPH, Kaza, 1 kWp SPV Power Plants in 100 premises of individual households at Pangi and Bharmour, 50 kWp SPV Power Plant at Indian Association of Muscular Dystrophy, Solan, 567 kWp SPV Power Plants in 34 Court Complexes in H.P and 5 Power Plants of 10 kWp SPV each at Village Bara Bhangal in Kangra district are in implementation stage.
The State Government is also providing funds under the Scheduled Caste Component Plan for the installation of SPV Street Lighting Systems in the Scheduled Caste villages which are having 40 per cent or more population of the Scheduled Caste. As many as 7961 SPV lights have been installed under this programme since inception. Apart from this, 55,230 SPV CFL Type Lanterns, 22,586 SPV Home Lights and 674 SPV LED Home Lights have been installed in the State during present tenure of State Government.


text:
Group affected by CIA brainwashing experiments wants public apology, compensation from government
A group of Canadians affected by CIA brainwashing experiments conducted at McGill University's Allan Memorial Institute met for the first time on Sunday to start organizing for a public apology and compensation from the federal government through a possible class-action.
Survivors Allied Against Government Abuse includes victims in brainwashing experiments in Montreal
Lisa Ellenwood · CBC News · Posted: May 21, 2018 7:21 AM ET | Last Updated: May 22, 2018
Alison Steel, who helped victims and their families connect, was overwhelmed on Sunday that everyone had finally come together. (Lisa Ellenwood/CBC)
Around 40 people gathered at a Montreal condo to share their stories, cry and support each other. The pain, many said, was palpable in the room.
"The government should offer an apology and there should be recognition of the injustice that was done," says Gina Blasbalg, who became a patient at the Allan in her teens in 1959, and drove with her husband from Richmond, B.C., to attend the weekend meeting.
Marilyn Rappaport, whose sister was a patient at the Allan Memorial Institute speaks to the SAAGA group on Sunday in Montreal. (Lisa Ellenwood/CBC)
Survivors Allied Against Government Abuse (SAAGA), as the group calls itself, includes both victims and family members of people who were unwitting participants in brainwashing experiments conducted under the supervision of Dr. Ewen Cameron, director of the psychiatric hospital between 1943 and 1964.
Cameron, co-founder of the World Psychiatric Association and president of various other psychiatric associations over his career, ran "depatterning" and "psychic driving" experiments that attempted to erase a patient's memories and reprogram them with new thoughts.
He tested experimental drugs like LSD and PCP, medically induced sleep for extended periods, and oversaw extreme forms of electroshock therapy and sensory deprivation. Many of his patient's brains were then left damaged.
WATCH | The Fifth Estate: Brainwashed: The secret CIA experiments in Canada
The federal government provided Cameron with more than $500,000 between 1950 and 1965 — $4 million in today's dollars — along with a smaller amount of funding from the U.S. Central Intelligence Agency, using a front organization called the Society for the Investigation of Human Ecology.
Today, many people argue that Cameron's experiments are part of the foundation for contemporary psychological torture techniques.
Children of Violet Winnifred Malboeuf: Laurel Malbeouf, left, Janice Shaw, centre left, Judy Henry, centre right, and Lorraine Taylor, right. (Lisa Ellenwood/CBC)
Four daughters of victim Violet Winnifred Malboeuf came from various towns in Quebec and Ontario to attend Sunday's meeting.
Janice Shaw explained that she and her siblings all had extremely difficult childhoods without their mother, but now they are relieved to know that there are other people to talk to who went through similar experiences.
The sisters and their two brothers were placed in foster care because their mother was incapable of raising them after her stay at the Allan Memorial Institute. A few days ago, they received some of their mother's medical records from the Department of Justice. One of the documents was a handwritten letter by their mother outlining her experience at the Allan.
Intrigued by case of compensation
Sunday's gathering would not have happened without CBC News investigative journalist Elizabeth Thompson. She regularly checks the government public account records for story ideas, and noticed a line about compensation for someone who had been depatterned at the Allan Memorial Institute.
Federal government quietly compensates daughter of brainwashing experiments victim
Thompson, who grew up in Montreal and worked for local newspapers, knew the history of the Allan Memorial Institute and was intrigued.
She called Montreal lawyer Alan Stein, who has represented numerous survivors of the Allan, and he confirmed that one of his clients, Alison Steel, was the person who received the compensation last year — long after her father first attempted to get compensation in the 1990s.
Gina and Ralph Blasbalg, both wearing white shirts, drove from Richmond, B.C., to attend the Montreal meeting. (Lisa Ellenwood/CBC)
They had reached an out-of-court settlement with the Canadian justice department in exchange for dropping the lawsuit, and Steel had to sign a non-disclosure agreement.
The recent CBC News articles and The Fifth Estate documentary Brainwashed led to a flood of emails from victims and their families. People wanted to know how to access medical records and compensation, and more than anything they wanted to connect with each other. Steel agreed to talk with them so The Fifth Estate sent along their emails.
Trudeau government gag order in CIA brainwashing case silences victims, lawyer says
"For awhile there I was receiving two or three calls per day," Steel says. "People didn't want to talk about it, but now they are realizing that so many others are in the same boat."
At the meeting, Steel was overwhelmed that everyone had finally come together.
Last February, they organized a private Facebook group and came up with a name. They created SAAGA, with the goal of seeking justice, a public apology and compensation.
Help in launching class-action suit
SAAGA announced at the Sunday meeting that Stein has agreed to assist the group in launching a class-action lawsuit to sue the Canadian government, maybe also the Quebec government and the Allan Memorial Institute. It would first have to be approved by the Quebec Superior Court, which could take four to six months, Stein said.
In an email, the Justice Department told CBC News that a 1986 inquiry by George Cooper into Cameron's depatterning work "concluded that Canada did not hold any legal liability or moral responsibility in respect of these treatments."
"As this matter may be before the courts it would be inappropriate to comment further."
The Fifth Estate began exposing wrongdoing at the Allan Memorial Institute in 1980 and continues to follow this story. We are in the process of building a website where we will gather together the stories of patients who underwent the brainwashing experiments, and their families.
If you would like to share your family's story, please send us an email: AMIstories@cbc.ca. We will try to include as many stories as possible on the website.
With files from CBC's Elizabeth Thompson
'She went away, hoping to get better': Family remembers Winnipeg woman put through CIA-funded brainwashing
Stranger than fiction: The real-life CIA projects that inspired 'Stranger Things'

redpajama_set_name: RedPajamaCommonCrawl


text:
When Rouhani (Almost) Met Trump
Iranwire – In a new book set shortly to be published in Iran, Without Smoke and Fire and Blood, former president Hassan Rouhani provides an oral history of his eight-year presidency of the Islamic Republic. Already released parts of the book include an account of when, in 2019, while Rouhani was in New York to attend the US General Assembly, he came very …
Monthly report August 2022, Iran Human Rights Monitor
August 2022 saw a spree of executions and the brutal suppression of civil liberties. At least 51 people were executed in August including a woman and two child offenders. Iranian authorities increased persecution of the Baha'i religious minority last month through raids, arbitrary arrests, home demolitions, and land grabs. These are a part of the issues covered in this monthly …
Hezbollah at 40 stronger than ever but has more enemies
Al-Arabia – Forty years since Hezbollah was founded at the height of Israel's 1982 invasion of Lebanon, the group has morphed from a ragtag organization to the largest and most heavily armed militant group in the Middle East. The Iranian-armed and funded Hezbollah, which has marked the anniversary with ceremonies in its strongholds in recent weeks, dominates Lebanon's politics and plays an …
Iran says has not received US response on nuclear proposal
Al-Arabia – Iran has not received the United States' official response to its last proposal on the revival of the 2015 nuclear deal, foreign ministry spokesman Nasser Kanani said Monday. "Iran is waiting to receive the response from other parties, notably that of the American government," he said during his weekly news conference in Tehran. His remarks come after the …
Two Iranian Women Sentenced To Death For LGBT Activism
RFL/RE – Two Iranian women have been sentenced to death for their activism in support of the country's LGBT community. The state IRNA news agency reported the sentences of Zahra Hamadani and Elham Chubdar on September 5, a day after the Hengaw human rights network said it had received reports that the two were informed of the punishment a few days earlier. …
Hollywood Actors Condemn Iran's Persecution of Baha'is
Iranwire – Three Hollywood actors and celebrities, Mark Ruffalo, Rainn Wilson and Justin Baldoni, have denounced the Iranian government's ongoing persecution of the Baha'i community in a series of tweets published last week. The interventions came after security agents arrested 13 young Baha'is in the city of Ghaemshahr in Iran's Mazandaran province. No charges against the young Baha'is have been announced. "This is very …
Iranian Authorities Arrest 12 Baha'i Members in Continuing Crackdown on Faith
VOA – Iran has stepped up its actions against Baha'i citizens, arresting 12 believers Tehran accuses of being "heretics" and having links to Israel in a continuing crackdown that has been condemned by Iranian and global rights groups. Iranian state media on Sunday said the arrests took place in different cities in Mazandaran province, the same area where 14 members …
Shabtabnews – In a twitter statement USCRIF commissioner expressed concern in regards to well-being of Kasra Nouri, a Sufi prisoner who has been imprisoned in Iran for being a Sufi for number of years. USCIRF Commissioner @imammagid: "USCIRF is also concerned for Kasra Nouri's well-being in light of his transfer Saturday to the Ministry of Intelligence Office in Shiraz for …
Baluch political prisoners executed at southeastern Iran prison
Iran-HRM – Baluch activists reported that two political prisoners, one of whom was a child at the time of his arrest, were executed today at the Central Zahedan Prison. The two Baluch political prisoners Mohsen Ghanbarzahi and Einollah Ghanbarzahi, were executed on Saturday, September 3, two days after being taken to solitary confinement. The two, who were relatives, were arrested …
Mohammad Khosravi Executed for Drug Offences in Arak
Iran Human Rights (IHRNGO) – Mohammad Khosravi was executed for drug-related offences in Arak Central Prison along with Hamid Ghareh Lar. According to newly obtained information by Iran Human Rights, another man was executed in Arak Central Prison on August 31. His identity has been established as 30-year-old Mohammad Khosravi who was sentenced to death for drug-related charges by the Revolutionary …


PREMIUM STALLION ZOOM (bred by DMJ HORSES) licensed at the Westphalian Main Licensing and awarded **RESERVE CHAMPION** The stallion is sold to "Landgestüt Warendorf" in Germany.
DMJ HORSES - Dressage Horses of Quality!
Please see our video presentation below!
We are pleased to introduce our breeding program of dressage horses, based upon carefully chosen mares of exquisite inter-national bloodlines.
Through the years, our horses have achieved top scores in young horse competitions and qualified for the FEI World Breeding Dressage Champion-ships for Young Horses in Verden/GER and Ermelo/NED (see video below).
Apart from that, we have bred foals and sport horses for the German Elite Auctions, several State Premium mares, the licensed stallions DANNEBROG (based at Celle State Stud/GER) and the Double Premium & Reserve Champion ZOOM (based at Warendorf State Stud /GER).
DMJ DONNA ELENA becomes National 5-year-old & 6-year-old Champion in Australia and qualifies for the FEI World Breeding Dressage Championships for Young Horses in Verden/GER 2015 and in Ermelo/NED 2016.


text:
25 October 2016 by Susannah Birkwood
The finding is based on research by a professor at Texas Tech University in the US
Fundraisers' job titles can affect the likelihood of donors engaging in conversation with them about donations, new research has found.
The paper, Testing the Effectiveness of Fundraiser Job Titles in Charitable Bequest and Complex Gift Planning by Russell James, a professor at Texas Tech University in the US, found that fundraisers with traditional "institution-focused" job titles – such as "director of development" or "director of institutional advancement" were less likely to be contacted by donors to discuss their donations than people with gift-centred or donor-centred alternatives.
The research was based on a survey of 3,188 US adults who were shown 63 job titles and asked who they would be most likely to contact in four giving scenarios: a charitable bequest gift; a gift of corporate shares; a gift of property; and a charitable gift annuity.
The worst-performing titles were those that focused on the charities concerned, in particular those using the terms "advancement", "institutional advancement" or "development", including when respondents who had made large gifts ($500 or more) were taken into account. The worst-performing job title of all was "director of advancement".
The research did not identify a clear best-performing job title, but it did find that gift-focused titles, particularly those referencing "gift planning" or "planned giving" performed well, possibly because they were tested in scenarios involving legacy gifts and charitable gift annuities. Titles specifically referencing the donor, such as "financial adviser for donors", "director of donor advising" and "director of donor guidance" also performed strongly.
"Institution-centred job titles may not be as effective with donors given the modern shift toward donor-centred philanthropy," says the paper. "Non-profit managers might do well to consider the donor's perspective when selecting job titles for fundraisers rather than following traditional industry practices."
The paper says, however, that institution-focused job titles might have positive attributes among workers, colleagues and job applicants at the charities concerned, which might offset the negative impact they have on donor engagement.
It also says that charities might risk creating a false perception by adopting titles that go too far in suggesting the fundraiser is there to provide donor-centred advice.
It notes that fundraisers might also reject job titles that communicate to their managers that they do not fully and exclusively represent their charity.
"This highlights the conflict between the need in modern philanthropy to be donor centred and the reality that, contractually, fundraisers answer only to the institution," the paper says.
It says that one way to avoid this conflict would be to use donor-oriented titles that do not specifically imply donor representation or benefit. Although not performing quite as well as other options, the more neutral donor-centric titles "chief donor relations officer", "chief donor officer" and "director of donor relations" all performed better than average.
Another strategy recommended by the paper, which avoids the "donor versus institution" conflict, is to use "gift centred" job titles, such as "director of trusts, estates and gift planning" or "director of estate gift planning".
The paper says: "The fundraiser focused on 'gift planning' appears as one who has knowledge and experience, especially in the context of complex scenarios, and can thus be a valuable resource for the donor without having to make an express representation of 'donor versus institution' allegiances."
Legacy appeals featuring 'living donors' more likely to be successful, research finds
Using the phrase 'a gift in your will' gets best results for legacy fundraisers, says report
Reminders about tribute legacies increase donors' interest, research finds


text:
/**
 *
 */
package sql.joinStatements;

import hydra.Log;
import hydra.TestConfig;

import java.math.BigDecimal;
import java.sql.Connection;
import java.sql.PreparedStatement;
import java.sql.SQLException;
import java.sql.ResultSet;
import java.util.ArrayList;
import java.util.List;

import com.gemstone.gemfire.cache.query.Struct;

import sql.SQLHelper;
import sql.SQLPrms;
import util.TestException;
import sql.sqlutil.ResultSetHelper;
import sql.dmlStatements.*;

/**
 * @author eshu
 *
 */
public class SecuritiesPortfolioJoinStmt extends AbstractJoinStmt {
  /*
   * trade.securities table fields
   *   private int sec_id;
   *   String symbol;
   *   String exchange;
   *   BigDecimal price;
   *   int tid; //for update or delete unique records to the thread
   *
   * trade.Portfolio table fields
   *   int cid;
   *   int sid;
   *   int qty;
   *   int availQty;
   *   BigDecimal subTotal;
   *   int tid; //for update or delete unique records to the thread
   */

  protected static String[] uniqSelect =
  {"select * from trade.securities s, trade.portfolio f where sec_id = f.sid and f.tid = ?",
   "select cid, sid, symbol, price, qty from trade.securities s, trade.portfolio f where sec_id = f.sid and cid >? and f.tid = ? ",
   "select cid, sid, symbol, exchange, qty, price from trade.securities s, trade.portfolio f where sec_id = f.sid and cid<? and(qty=availQty or price > ?) and f.tid = ?",
   "select cid, sid, symbol, exchange, price, subtotal from trade.securities s, trade.portfolio f where sec_id = f.sid and cid >? and (subtotal >10000 or (price >= ? and price <= ?)) and f.tid = ?",
   /*comment out due to #41567*/
   // "select cid, sid, symbol, exchange, price, subtotal from trade.securities s LEFT OUTER JOIN trade.portfolio f ON sec_id = f.sid where f.tid=? "
    };

  protected static String[] nonUniqSelect = {
    "select * from trade.securities s, trade.portfolio f where sec_id = f.sid ",
    "select cid, sid, symbol, price, qty from trade.securities s, trade.portfolio f where sec_id = f.sid and cid >? ",
    "select cid, sid, symbol, exchange, qty, price from trade.securities s, trade.portfolio f where sec_id = f.sid and cid<? and(qty=availQty or price > ?) ",
    "select cid, sid, symbol, exchange, price, subtotal from trade.securities s, trade.portfolio f where sec_id = f.sid and cid >? and (subtotal >10000 or (price >= ? and price <= ?)) ",
    /*comment out due to #41567*/
 //   "select cid, sid, symbol, exchange, price, subtotal from trade.securities s LEFT OUTER JOIN trade.portfolio f ON sec_id = f.sid  "
    };

  protected static String[] uniqSelectHdfs =
  {"select * from trade.securities s, trade.portfolio f  -- GEMFIREXD-PROPERTIES queryHDFS=true \n where sec_id = f.sid and f.tid = ?",
   "select cid, sid, symbol, price, qty from trade.securities s, trade.portfolio f  -- GEMFIREXD-PROPERTIES queryHDFS=true \n where sec_id = f.sid and cid >? and f.tid = ? ",
   "select cid, sid, symbol, exchange, qty, price from trade.securities s, trade.portfolio f  -- GEMFIREXD-PROPERTIES queryHDFS=true \n where sec_id = f.sid and cid<? and(qty=availQty or price > ?) and f.tid = ?",
   "select cid, sid, symbol, exchange, price, subtotal from trade.securities s, trade.portfolio f -- GEMFIREXD-PROPERTIES queryHDFS=true \n where sec_id = f.sid and cid >? and (subtotal >10000 or (price >= ? and price <= ?)) and f.tid = ?",
   /*comment out due to #41567*/
   // "select cid, sid, symbol, exchange, price, subtotal from trade.securities s LEFT OUTER JOIN trade.portfolio f ON sec_id = f.sid where f.tid=? "
    };

  protected static String[] nonUniqSelectHdfs = {
    "select * from trade.securities s, trade.portfolio f  -- GEMFIREXD-PROPERTIES queryHDFS=true \n where sec_id = f.sid ",
    "select cid, sid, symbol, price, qty from trade.securities s, trade.portfolio f  -- GEMFIREXD-PROPERTIES queryHDFS=true \n  where sec_id = f.sid and cid >? ",
    "select cid, sid, symbol, exchange, qty, price from trade.securities s, trade.portfolio f  -- GEMFIREXD-PROPERTIES queryHDFS=true \n where sec_id = f.sid and cid<? and(qty=availQty or price > ?) ",
    "select cid, sid, symbol, exchange, price, subtotal from trade.securities s, trade.portfolio f  -- GEMFIREXD-PROPERTIES queryHDFS=true \n  where sec_id = f.sid and cid >? and (subtotal >10000 or (price >= ? and price <= ?)) ",
    /*comment out due to #41567*/
 //   "select cid, sid, symbol, exchange, price, subtotal from trade.securities s LEFT OUTER JOIN trade.portfolio f ON sec_id = f.sid  "
    };

  protected static boolean isColocated = checkColocation();
  protected static boolean[] useDisk = {false};

  public SecuritiesPortfolioJoinStmt(){

  }

  //---- implementations of interface declared methods ----//

  public void query(Connection dConn, Connection gConn) {
    int whichQuery;
    ResultSet derbyRS;
    ResultSet gfeRS;
    int cid = (dConn !=null ) ? AbstractDMLStmt.getCid(dConn) : AbstractDMLStmt.getCid(gConn); //cid to this thread if uniq
    int maxPrice = 100; //max price in the test is 100
    BigDecimal price1 = new BigDecimal(Integer.toString(rand.nextInt(maxPrice/2)));
    BigDecimal price2 = price1.add(new BigDecimal(Integer.toString(rand.nextInt(maxPrice/2))));
    int tid = AbstractDMLStmt.getMyTid();

    if (dConn!=null) {
      if (testUniqueKeys) { //test uniqKeys
        whichQuery = rand.nextInt(uniqSelect.length);
        derbyRS = getUniqQuery(dConn, whichQuery, cid, price1, price2, tid);
        if (derbyRS == null) {
          Log.getLogWriter().info("Did not execute this query");
          return;
        }
        List<Struct> derbyList = ResultSetHelper.asList(derbyRS, true);
        if (derbyList == null) {
          Log.getLogWriter().info("Not able to convert derby resultSet to a list");
          return;
        }
        gfeRS = getUniqQuery (gConn, whichQuery, cid, price1, price2, tid);
        if (gfeRS==null && !isColocated) {
          Log.getLogWriter().info("tables are not colocated so not able to verify results");
          return;
        }
        List<Struct> gfeList = ResultSetHelper.asList(gfeRS, false);
        if (gfeList==null && isHATest) {
          Log.getLogWriter().info("could not get gfxd results set due to HA");
          return;
        }
        ResultSetHelper.compareResultSets(derbyList, gfeList);
      } else {
        whichQuery = rand.nextInt(nonUniqSelect.length);
        derbyRS = getNonUniqQuery(dConn, whichQuery, cid, price1, price2, tid);
        if (derbyRS == null) {
          Log.getLogWriter().info("Did not execute this query");
          return;
        }
        List<Struct> derbyList = ResultSetHelper.asList(derbyRS, true);
        if (derbyList == null) {
          Log.getLogWriter().info("Not able to convert derby resultSet to a list");
          return;
        }
        gfeRS = getNonUniqQuery (gConn, whichQuery, cid, price1, price2, tid);
        List<Struct> gfeList = ResultSetHelper.asList(gfeRS, false);
        if (gfeList==null && isHATest) {
          Log.getLogWriter().info("could not get gfxd results set due to HA");
          return;
        }
        ResultSetHelper.compareResultSets(derbyList, gfeList);
      }
    }// we can verify resultSet
    else {
      whichQuery = rand.nextInt(nonUniqSelect.length);
      synchronized (useDisk){
        gfeRS = getNonUniqQuery (gConn, whichQuery, cid, price1, price2, tid);
        //could not verify results.
        if (gfeRS==null & useDisk[0]==true) {
          Log.getLogWriter().info("not able to get the results set due to size is too large");
          useDisk[0] = false;
          return;
        }
      }
      ResultSetHelper.asList(gfeRS, false);
    }

  }

  //---- other methods ----//

  //retries when lock could not obtained
  public static ResultSet getUniqQuery(Connection conn, int whichQuery, int cid,
      BigDecimal price1, BigDecimal price2, int tid) {
    boolean[] success = new boolean[1];
    ResultSet rs = null;
    rs = getUniqQuery(conn, whichQuery, cid, price1, price2, tid, success);
    int count=0;
    while (!success[0]) {
      if (count>=maxNumOfTries) {
        Log.getLogWriter().info("Could not get the lock to finish update in derby, abort this operation");
        return rs;
    }
      count++;
      rs = getUniqQuery(conn, whichQuery, cid, price1, price2, tid, success);
    } //retry
    return rs;
  }

  public static ResultSet getUniqQuery(Connection conn, int whichQuery, int cid, BigDecimal price1, BigDecimal price2, int tid, boolean[] success) {
    PreparedStatement stmt;
    ResultSet rs = null;
    success[0] = true;
    try {

      Boolean hasHdfs = TestConfig.tab().booleanAt(SQLPrms.hasHDFS, false);
      String database = SQLHelper.isDerbyConn(conn)?"Derby - " :"gemfirexd - ";
      String query = (! SQLHelper.isDerbyConn(conn) && hasHdfs ) ? " QUERY: " +  uniqSelectHdfs[whichQuery] : " QUERY: " +  uniqSelect[whichQuery];
      stmt = (! SQLHelper.isDerbyConn(conn) && hasHdfs )  ? conn.prepareStatement(uniqSelectHdfs[whichQuery]) :  conn.prepareStatement(uniqSelect[whichQuery]) ;

      switch (whichQuery){
      case 0:
        //"select * from trade.securities s, trade.portfolio f where sec_id = f.sid and f.tid = ?",
        Log.getLogWriter().info(database + "Querying SecuritiesPortfolio with TID:"+ tid + query);
        stmt.setInt(1, tid);
        break;

      case 1:
        //"select cid, sid, symbol, price, qty from trade.securities s, trade.portfolio f where sec_id = f.sid and cid >? and f.tid = ? ",
        Log.getLogWriter().info(database + "Querying SecuritiesPortfolio with CID:" + cid + ",TID:"+ tid +  query);
        stmt.setInt(1, cid);
        stmt.setInt(2, tid);
        break;

      case 2:
        //"select cid, sid, symbol, exchange, qty, price from trade.securities s, trade.portfolio f where sec_id = f.sid and cid<? and(qty=availQty or price > ?) and f.tid = ?",
        Log.getLogWriter().info(database + "Querying SecuritiesPortfolio with CID:" + cid + ",PRICE:"+ price1 + ",TID:"+ tid + query);
        stmt.setInt(1, cid); //set cid<=?
        stmt.setBigDecimal(2, price1);
        stmt.setInt(3, tid);
        break;

      case 3:
        //"select cid, sid, symbol, exchange, price, subtotal from trade.securities s, trade.portfolio f where sec_id = f.sid and cid >? and (subtotal >10000 or (price >= ? and price <= ?) and f.tid = ?"
        Log.getLogWriter().info(database + "Querying SecuritiesPortfolio with CID:" + cid + ",1_PRICE:"+ price1 + ",2_PRICE:" + price2 + ",TID:"+ tid + query);
        stmt.setInt(1, cid); //set cid>?
        stmt.setBigDecimal(2, price1);
	stmt.setBigDecimal(3, price2);
        stmt.setInt(4, tid);
        break;

      case 4:
        //left out join
        Log.getLogWriter().info(database + "Querying SecuritiesPortfolio with LEFT OUTER JOIN TID:"+ tid + query);
        stmt.setInt(1, tid);
        break;

      default:
        throw new TestException("incorrect select statement, should not happen");
      }
      rs = stmt.executeQuery();
    } catch (SQLException se) {
      if (!SQLHelper.checkDerbyException(conn, se)) success[0] = false; //handle lock could not acquire or deadlock
      else if (se.getSQLState().equals("0A000") && testServerGroup && !isColocated) {
        SQLHelper.printSQLException(se);
        Log.getLogWriter().info("got the expected non colocated exception, continuing tests.");
      } //if it is not colocated, it may throw exception
      else      SQLHelper.handleSQLException(se);
    }
    return rs;
  }

  //retries when lock could not obtained
  public static ResultSet getNonUniqQuery(Connection conn, int whichQuery, int cid,
      BigDecimal price1, BigDecimal price2, int tid) {
    boolean[] success = new boolean[1];
    ResultSet rs = null;
    rs = getNonUniqQuery(conn, whichQuery, cid, price1, price2, tid, success);
    while (!success[0]) {
      rs = getNonUniqQuery(conn, whichQuery, cid, price1, price2, tid, success);
    } //retry
    return rs;
  }

  public static ResultSet getNonUniqQuery(Connection conn, int whichQuery, int cid,
      BigDecimal price1, BigDecimal price2, int tid, boolean[] success) {
    PreparedStatement stmt;
    ResultSet rs = null;
    success[0] = true;
    try {

      Boolean hasHdfs = TestConfig.tab().booleanAt(SQLPrms.hasHDFS, false);
      String database = SQLHelper.isDerbyConn(conn)?"Derby - " :"gemfirexd - ";
      String query = (! SQLHelper.isDerbyConn(conn) && hasHdfs ) ? " QUERY: " +  nonUniqSelectHdfs[whichQuery] : " QUERY: " +  nonUniqSelect[whichQuery];
      stmt = (! SQLHelper.isDerbyConn(conn) && hasHdfs )  ? conn.prepareStatement(nonUniqSelectHdfs[whichQuery]) :  conn.prepareStatement(nonUniqSelect[whichQuery]) ;

      switch (whichQuery){
      case 0:
        //"select * from trade.securities s, trade.portfolio f where sec_id = f.sid and f.tid = ?",
        Log.getLogWriter().info(database +"Querying SecuritiesPortfolio with no data" + query);
        break;

      case 1:
        //"select cid, sid, symbol, price, qty from trade.securities s, trade.portfolio f where sec_id = f.sid and cid >? and f.tid = ? ",
        Log.getLogWriter().info(database +"Querying SecuritiesPortfolio with CID:" + cid + query);
        stmt.setInt(1, cid);
        break;

      case 2:
        //"select cid, sid, symbol, exchange, qty, price from trade.securities s, trade.portfolio f where sec_id = f.sid and cid<? and(qty=availQty or price > ?) and f.tid = ?",
        Log.getLogWriter().info(database +"Querying SecuritiesPortfolio with CID:" + cid + ",PRICE:"+ price1 + query );
        stmt.setInt(1, cid); //set cid<=?
        stmt.setBigDecimal(2, price1);
        break;

      case 3:
        //"select cid, sid, symbol, exchange, price, subtotal from trade.securities s, trade.portfolio f where sec_id = f.sid and cid >? and (subtotal >10000 or (price >= ? and price <= ?) and f.tid = ?"
        Log.getLogWriter().info(database +"Querying SecuritiesPortfolio with CID:" + cid + ",1_PRICE:"+ price1 + ",2_PRICE:" + price2 + query);
        stmt.setInt(1, cid); //set cid>?
        stmt.setBigDecimal(2, price1);
        stmt.setBigDecimal(3, price2);
        break;

      case 4:
        //Left outer join
        Log.getLogWriter().info(database +"Querying SecuritiesPortfolio with LEFT OUTER JOIN " + query);
        break;

      default:
        throw new TestException("incorrect select statement, should not happen");
      }
      rs = stmt.executeQuery();
    } catch (SQLException se) {
      if (!SQLHelper.checkDerbyException(conn, se)) success[0] = false; //handle lock could not acquire or deadlock
      else if (se.getSQLState().equals("0A000") && se.getMessage().matches(".*disk.*")) {
        SQLHelper.printSQLException(se);
        Log.getLogWriter().info("got the unsupported exception, need to remove this once bug#40348 is fixed, continuing test");
        useDisk[0] = true;
        return null;
      }
      else      SQLHelper.handleSQLException(se);
    }
    return rs;
  }

//to check if the tables are colocated
  protected static boolean checkColocation() {
    if (testServerGroup) {
      boolean isSecPortfCol = false;

      String secSG = (String) map.get("securitiesSG");
      String portfSG = (String) map.get("portfolioSG");
      String schemaSG = (String) map.get(tradeSchemaSG);
      String[] secSGArr = secSG.split(",");
      String[] portfSGArr = portfSG.split(",");
      String[] schemaSGArr = schemaSG.split(",");

      ArrayList<String> secSGList = new ArrayList<String>();
      ArrayList<String> portfSGList = new ArrayList<String>();
      ArrayList<String> schemaSGList = new ArrayList<String>();

      for (int i=0; i<schemaSGArr.length; i++)
        schemaSGList.add(schemaSGArr[i]); //get sever groups for schema

      if (portfSG.equals("default")) {
        portfSGList.remove("default");
        portfSGList.addAll(schemaSGList);  //portoSG has the same SG as schema, "default" could be added back indicating in all SG
      } else {
        for (int i=0; i<portfSGArr.length; i++)
          portfSGList.add(portfSGArr[i]); //get sever groups for portfolio
      }

      if (secSG.equals("default")) {
        secSGList.remove("default");
        secSGList.addAll(schemaSGList);  //secSG has the same SG as schema
      } else {
        for (int i=0; i<secSGArr.length; i++)
          secSGList.add(secSGArr[i]); //get sever groups for securities
      }

      ArrayList secParti = (ArrayList) map.get("securitiesPartition");
      ArrayList portfParti = (ArrayList) map.get("portfolioPartition");

      if (secParti.size() > 0 && portfParti.size()>0) {
        if (!portfSG.equals(secSG)) isSecPortfCol = false; //please note xxxSG are set string
        else {
          if (secParti.size()== 1 && secParti.get(0).equals("sec_id")
              && portfParti.size()== 1 && portfParti.get(0).equals("sid")
              && ((String)map.get("portfPartitionOn")).equals("default"))
            //when server groups are same to check if both tables are partitioned on sid
            //if so, check if portfolio use default partition/colocation
            isSecPortfCol = true;
        }
      } //both tables are partitioned, no replicate

      else if (secParti.size() == 0 && portfParti.size()>0 ) {
        if (secSGList.contains("default")) {
          isSecPortfCol = true;
        } //sec is replicated to all servers
        else {
          if (secSGList.contains(portfSGList))
            isSecPortfCol = true; //portf in the server groups that are a subset of sec
        }
      } /*only sec table is replicate */

      else if (portfParti.size()==0 && secParti.size() >0) {
        if (portfSGList.contains("default")) {
            isSecPortfCol = true;
        } //portf is replicated to all servers
        else {
          if (portfSGList.contains(secSGList))
            isSecPortfCol = true; //sec in the server groups that are a subset of portf
        }
      } //portf table is replicated
      else {
        for (int i=0; i<portfSGArr.length; i++) {
          if (secSGList.contains(portfSGArr[i])) {
            isSecPortfCol = true;
            break;
          }
        } //none has "default" case
        if (secSGList.contains("default") || portfSGList.contains("default")) {
          isSecPortfCol = true;
        } //only cust has default server groups
      } //both tables are replicated

      if (isSecPortfCol) {
        Log.getLogWriter().info("portfolio and securities tables are colocated");
        return true; //if both are colocated
      }
      else {
        Log.getLogWriter().info("portfolio and securities tables are not colocated");
        return false;
      }
    }
    return true; //default to true, any test config does not involve server group need to make sure the tables are colocated.
  }

}

redpajama_set_name: RedPajamaGithub


CHERRY HILL - Want to see Dr. Mehmet Oz, live and up close?
Arrive at the Cherry Hill Mall when doors open at 7 a.m. on Saturday, Aug. 25, and prepare to wait.
Dr. Oz will be on stage from noon to 1:30 p.m.
As headliner of the mall's Health and Wellness Expo, the Emmy-winning host of "The Dr. Oz Show" will lead a panel discussion with two Jefferson Health doctors and will share a video presentation, "The Good Life," from noon to 1:30 p.m. on the Grand Court stage near Nordstrom.
About 1,000 chairs will be set up for audience members, and about 300 people can stand behind them or on the mall's upper level overlooking the court, said Lisa Wolstromer, the mall's senior marketing director. Audience members also can watch a giant LED screen of the action.
The mall is expecting "enthusiastic crowds," said Wolstromer.
"I recommend that people who want to get a seat come early and reserve their seat, but it is first-come, first-serve," Wolstromer said.
During the panel discussion, Oz will talk about women's health and breast health with Dr. Greg Taylor, a Haddonfield family physician, and Dr. Kahyun Yoon-Flannery, a breast surgeon in Washington Township.
The expo runs from 11 a.m. to 4 p.m., and includes health and fitness presentations. Jefferson Health, the expo's healthcare sponsor, will offer CPR training, healthy cooking demonstrations, chair yoga, a presentation on breast health, sports injuries and weight loss surgery.
More than 20 local health, lifestyle and safety experts, including doctors, dentists, surgeons and fitness instructors, will be on hand throughout the mall to answer questions.
To register for the event, visit www.eventbrite.com/e/dr-oz-at-cherry-hill-mall-tickets-48694034167. Registration does not guarantee a seat.
Is your child up to date with back-to-school immunizations?


Before we come together with family and friends for Thanksgiving, join us as we cultivate gratitude through movement, breath and meditation bringing that essence with us into the rest of our day.
Cost is $25 ($20 if paid by November 20). Space is limited. Pre-registration and pre-payment is required to reserve your space. Register online or for more information, email Debra@RBYoga.com. Due to the limited size of this special offering, we cannot provide refunds or class transfers. Thank you for your understanding.


text:
« Cuba 2012: Colonial Havana, Lush Countryside, End of Socialist Experiment
2012: Aging Athlete »
2012: Zazzle Bay to Breakers
"Zazzle" it may be called, but the race was razzle-dazzle for most of the way and frazzle at the end for many. In fact, the race, or more accurately race-run-jog-walk, depending on ability, was better organized than in past years. The 40,000 participants were corralled in streams by ability—elite, good, slow, very slow, extremely slow, painfully slow runners and walkers. The starting times were also staggered, although the first four groups started at the same time. Despite these improvements, it took about 10 minutes to get to the starting line because there were so many people. Not that it mattered because most of us were busy listening to rock music, playing Frisbee with tortillas and watching a dizzying variety of costumes and colors on people of all ages, shapes and sizes. There were nude runners, but sadly they were all men, mostly old with sagging flesh or overweight with wobbling fat. Why would they want to be seen like that?More interesting were the teams connected to each other as snakes, dragons, a Bratwurst sausage and a wedding party complete with bunches of empty beer cans dragging along the street. Among the women, popular outfits included superwoman, flowing see-through pantaloons from Arabian nights and skimpy bikinis. I met and chatted with a Confidence Fairy that Paul Krugman says exists in the minds of Republicans in the US, Tories in the UK and Angela Merkel who think that austerity will rejuvenate investment and growth.
I had injured my Achilles tendon three years ago and was advised not to run. Although playing tennis was allowed, I needed to ice that area afterwards to calm the inflammation. Feeling constrained, in early February I challenged my doctor's advice and set the goal of finishing this race and started to train for it. I was ready by the end of April, but pulled a muscle playing tennis early in May. With help from a great physio-masseur, I felt sufficiently recovered to at least give it a try.
I kept pace with my very slow group until we hit the dreaded Hayes hill, about half a mile of steep climbing. After a couple of hundred yards, we hit a logjam because many in front began to walk. I had prepared for the hill and was determined not to join them, so I plodded on bobbing and weaving trough the walkers.
After the hill, the route is flat for a mile and then goes downhill for about four miles through Golden Gate Park to the ocean where the race ends. At the park's entrance, wind stamina was no longer an issue, but leg strength was. To make matters worse, I felt an ache in the muscle I had pulled. I chose to ignore it hoping it would fade and luckily it did.
The sight of the ocean was a relief. I knew I would finish and had enough left in me to accelerate my pace from very slow to slow for the last half mile. This small thrill reminded me of the last half mile of my first marathon in New York in 1979. When I came into Central Park South and felt sure I would finish, I was overcome with emotion. I have not felt that sense of achievement in anything else I have done. Little things please little minds, I suppose.
Another benefit of training for this race has been the ramped up production of endorphins that has improved my mood greatly. Because I saw many other runners who looked well into their 80s, and maybe 90s, I am comforted by the thought of having, at 73, many years left of running and feeling great.
At the finish line, we got a nice pewter medal and coconut juice. But it was a long walk to the bus organized to take us back to the start and an even longer trip on the bus snailing its way through snarled traffic. I was lucky to sit and chat with three Irish Thoracic surgeons who were attending a conference in San Francisco and took the opportunity to run the race.


text:
In der Stadt Nürnberg gibt es drei (Stand Dezember 2018) Naturschutzgebiete.

Siehe auch
 Liste der Landschaftsschutzgebiete in der Stadt Nürnberg
 Liste der geschützten Landschaftsbestandteile in Nürnberg
 Liste der Naturdenkmäler in Nürnberg
 Liste der FFH-Gebiete in der Stadt Nürnberg
 Liste der Geotope in Nürnberg

 Liste der Naturschutzgebiete im Landkreis Nürnberger Land
 Liste der Landschaftsschutzgebiete im Landkreis Nürnberger Land
 Liste der FFH-Gebiete im Landkreis Nürnberger Land
 Liste der geschützten Landschaftsbestandteile im Landkreis Nürnberger Land
 Liste der Naturdenkmäler im Landkreis Nürnberger Land
 Liste der Geotope im Landkreis Nürnberger Land

Einzelnachweise

Weblinks

 Naturschutzgebiete auf umweltatlas.nuernberg.de
 Umweltamt Nürnberg: Naturschutzgebiete

Nurnberg
!

redpajama_set_name: RedPajamaWikipedia


Glenn Loomis, M.D., was named CEO of St. Elizabeth Physicians, a group with 146 physicians and 38 offices in Northern Kentucky and Cincinnati. The group was formed in January with the merging of Summit Medical Group and Patient First Physician Group, which both were already owned by Covington, Ky.-based St. Elizabeth Healthcare but maintained separate leadership.
Loomis, 43 begins the job Sept. 1, taking over for interim CEO Todd Cook, M.D. For the past two years Loomis was president of St. Francis Medical Group, a practice of about 120 physicians in and around Indianapolis affiliated with St. Francis Hospital and Health Centers.


The dandy's choice for summer, the newsboy cap is narrower than our best-selling Tremelo cap and made from 100% navy linen.
The cap comes with a complimentary canvas cap bag.
Steam from a household kettle and a soft bristle hat brush will help remove dust and dirt. Brush the hat using short strokes.
This hat is not designed to be worn in the rain. Should you get this style wet, it should be dried at room temperature, never on top of a radiator.
Cotton and linen hats and caps should not be stored in direct sunlight.


text:
Home » News & Events » Research News » New drug could mean fewer symptoms and less gut damage for celiac disease patients
New drug could mean fewer symptoms and less gut damage for celiac disease patients
Yes, I want to advance research
No, I'd prefer not to
Don't show me this again
Study results presented at DDW offer hope for future protection from accidental gluten exposure
By Amy Ratner, Medical and Science News Analyst
Celiac disease patients who suffer symptoms and gut inflammation despite being on a gluten-free diet could get relief from both at the same time from a new drug being developed by Amgen, a study presented at Digestive Disease Week (DDW) showed.
Markku Maki, M.D., the principal investigator, detailed results of the study of AMG 714, a drug that neutralizes a molecule, called IL-15, that is believed to be a key driver in celiac disease.
Learn more: Watch Markku Maki describe the state of celiac disease research
"We are going from hype to hope," Maki, a celiac disease expert and professor at the University of Tampere in Finland, told the DDW audience of mainly physicians, gastroenterologists, researchers and academics.
He noted that up to half of celiac disease patients on a gluten-free diet have intestinal damage or inflammation and a third have ongoing symptoms.
While the new Amgen results, including a separate study of AMG 714 in the treatment of refractory celiac disease – a rare but severe form which can lead to lymphoma – received the most attention at DDW, the progress of others was also noted.
In the pipeline
Ciarán Kelly, M.D., director of the Celiac Center at Beth Israel Deaconess Medical Center and a member of the Beyond Celiac Board of Directors, outlined emerging therapies in a presentation at DDW, noting that 70 percent of patients in one survey said they are interested in new treatments for celiac disease.
"The gluten-free diet is not a prescription anyone can fill," Kelly said. He described the high burden, potential nutritional deficiencies, incomplete effectiveness, and minimal medical support related to the diet. Still, it continues to be the only treatment for celiac disease and the idea that it is all patients' need has "stifled research, he said. Consequently, celiac disease is "poised for drug development" Kelly added.
Read More: Patients on a gluten-free diet regularly get unsafe amounts of gluten
A number of drugs are currently being investigated, Kelly explained. They work in different ways, from breaking down gluten with enzymes, to interrupting the effect of gluten on the cells lining the intestine, to preventing or interrupting the immune reaction that occurs when people with celiac disease eat gluten. Each works in the body at a different point in the process that begins when someone with celiac disease eats gluten.
Among them are Innovate Biopharmaceutical's Larazotide Acetate, which is expected to go into phase 3 studies this year. A therapeutic vaccine that is a form of immunotherapy, NexVax 2 is also moving forward at a steady clip. Latiglutenase, another drug being developed, hit some bumps in the road in a recent trial that did not have the desired results, but researchers are still hopeful it can help celiac disease patients by degrading gluten with enzymes.
Learn more: Celiac disease drug pipeline
AMG 714 easing the effect of gluten
AMG 714 is an antibody that binds to IL-15, which is believed to play a key role in inflammation of the gut. The drug was originally tested for safety in patients with rheumatoid arthritis and psoriasis. Although it worked well in clinical studies related to inflammation, it was not pursued for those conditions, leading to its development as a treatment for non-responsive celiac disease.
Researchers wanted to measure the effect AMG 714 would have on patients exposed to gluten, something that often occurs in the real world despite best efforts to maintain a strict gluten free diet.
"Contamination, which can happen during food processing or packaging, during cooking and due to inadequate labeling, is known to occur very frequently, despite following a gluten-free diet," said Francisco Leon, M.D., study director and a consultant to Amgen. The hope is that the drug will allow celiac disease patients on the gluten-free diet to experience fewer gluten-triggered consequences.
Sixty participants the clinical trial conducted in Finland were divided into two groups. One group of about 35 received a 2.5 gram gluten challenge in the form of a cookie daily for 10 weeks. Another group of seven patients was not given the challenge because they had enough damage from gluten from cross-contact in their gluten-free diet at the start of the study.
Researchers then compared the effects of AMG 714 at two dose levels, 150 milligrams (mg) and 300 mg, to a third placebo group which did not receive any medication. Patients were given the drug through subcutaneous injection six times over 12 weeks.
Urine and stool samples were collected to objectively assess gluten consumption, something that enabled researchers to more precisely interpret results, the study said.
Subcutaneous injection: An injection in which the needle is injected just under the skin.
Randomized, double-blind placebo-controlled study: a study in which some participants are given the treatment, others are given a placebo, and neither the researchers nor the participants know which is which until the study end. The assignment of participants to treatment or placebo is done randomly. It is considered the gold standard of scientific testing for new medical interventions.
Primary endpoint: The main result that will answer the most important question being asked by a clinical trial.
The randomized, double-blind, placebo-controlled phase 2a study did not meet its primary endpoint of preventing damage to the intestine in the gluten challenge group, but a decrease in intestinal inflammation was seen. Meanwhile, researchers reported a trend toward less intestinal damage in the groups that did not get the challenge. Study participants also reported fewer symptoms, especially in the group that received the larger dose of AMG 714.
Active celiac disease: celiac disease that is not responding to treatment
And none of the patients in the gluten-challenge group who took the 300 mg dose had active celiac disease at the end of the study compared to one-third of the placebo group who had did, Maki found.
"AMG 714 is the first experimental medication which has shown a reduction in the effects of gluten on gut inflammation and symptoms simultaneously," Leon said.
The fact that the primary endpoint was not met means the drug won't allow celiac disease patients to eat a gluten-containing diet, Leon said. "But is still shows it could help with contamination gluten as an adjunct to the gluten-free diet," he explained.
He noted that there was a trend toward improvement in the group that did not receive the challenge but was exposed to their normal, real world exposure to gluten through cross-contact. Future studies with larger groups of patients are needed to determine the significance of this trend.
"A gluten-free diet has been the only treatment option for celiac disease patients, yet it is nearly impossible for them to avoid gluten entirely and indefinitely," Maki said. "That is why we have been investigating medications to help prevent the consequences of hidden gluten."
Amgen will be discussing a potential path forward for AMG 714 with regulators, said Kristen Davis, senior manager of corporate communications. Researchers emphasized that it is still in experimental stages and would not be available to patients until receiving needed approval from the U.S. Food and Drug Administration.
"AMG 714 is being studied as an adjunct to a gluten-free diet to prevent the consequences of contaminating gluten," Davis said. "It's important to note that this drug is being investigated for its potential to protect against modest contamination, not deliberately eating large amounts of gluten, like bread or pasta."
AMG 714 as a treatment for refractory celiac disease showed positive results by multiple measures in a separate study also presented at DDW and is expected to move into a phase three clinical trial.
Sign up to receive regular celiac disease research news updates.


A-Frame Mounted Sign, 24" x 36"
Increasing the visibility of your brand and business is a simple way to help drive traffic to both your physical locations as well as to your website. This A-frame poster can be placed in high-traffic areas to alert passersby to your latest events and promotions.
Simple way to let passersby know about your newest sales and events.
Sturdy, heavyweight paper construction can endure rough handling.


text:
Home » Sports News » Big Hype Prospects: Alvarez, Baty, Crow-Armstrong, Langeliers, Bello
Big Hype Prospects: Alvarez, Baty, Crow-Armstrong, Langeliers, Bello
Julio Rodriguez is on the verge of a massive contract extension. Who will be the next prospect to ink a mega-deal? Today's Big Hype Prospects won't answer that question, but it's possible we'll discuss them all the same.
Five Big Hype Prospects
Francisco Alvarez, 20, C, NYM (AAA)
141 PA, 6 HR, .180/.340/.378
Despite the triumphant return of Jacob deGrom, the Mets divisional aspirations are endangered. Their once dominant lead over the Braves has dwindled to just two games. The club has received exactly 0.0 WAR from their catchers. Alvarez, whose combination of discipline and rare raw power can lead to some irresponsible comps (like former Met Mike Piazza), has held his own at Triple-A. The low batting average is the result of an unfortunate .209 BABIP. Low BABIPs in the minors can be symptomatic of a flaw. Sometimes, they're just bad luck over a small sample. Alvarez had similar issues in High-A last season (.260 BABIP) so it's possible his plodding speed and pull-heavy approach might yield an all-or-nothing slugger, especially early in his career. Defensive reviews are mixed and can sometimes leave a Gary Sanchez-like taste on the tongue. He has the capacity and work ethic to stick at the position, but maybe his bat is too potent to subject to the rigors of battery work?
Alvarez would certainly upgrade the Mets lineup over the likes of James McCann and Tomas Nido. However, they're both talented defenders who have experience with the Mets pitching staff. If New York wants to experiment with Alvarez ahead of the postseason, now is the time to do it.
Brett Baty, 22, 3B, NYM (MLB)
35 PA, 1 HR, .161/.235/.258
Baty's first exposure to Major League pitching hasn't exactly gone according to plan. He had only 26 successful plate appearances at Triple-A before he was called upon. Much of his season was spent in Double-A where he hit .312/.406/.544 in 394 plate appearances. Baty is a disciplined hitter who makes hard, low-angle contact. With 91-mph average and 113-mph max exit velocities, he's already demonstrated his power in just 24 batted ball events. His tendency to keep the ball on the ground could yield a contact profile something like a less-extreme Yandy Diaz. Whereas Diaz is nigh immune to strikeouts, Baty has a bit of swing-and-miss in his game.
Eduardo Escobar is nearing a return which could spell the end of the Baty experiment – at least for 2022. It's also worth noting that his struggles have occurred over just nine games. He wouldn't be the first player to need a couple beats before catching his stride.
Pete Crow-Armstrong, 20, OF, CHC (A+)
235 PA, 9 HR, 16 SB, .286/.332/.521
Known to many prospect-watchers by his initials "PCA," Crow-Armstrong was acquired from the Mets as part of the Javier Baez trade in 2021. The Cubs instigated a mechanical change to his swing which has led to above average pull-side power this season. Including a thorough stomping of Low-A pitchers, PCA has 16 home runs and 29 stolen bases across 418 total plate appearances. He's a gifted center fielder who was originally expected to fit in the Majors as a defensive savant. The addition of power to his profile could unlock a star-level ceiling. There remain issues with his bat including elevated strikeout and swinging strike rates. He's young for his level and showed better plate discipline in the past. Consider him a volatile work-in-progress who now appears likely to have a role as a future regular.
Shea Langeliers, 24, C, OAK (MLB)
A key component of the Matt Olson trade, Langeliers has made an impactful debut. He's already popped two home runs, four doubles, and a triple in just nine games. That's par for the course with Langeliers. He has middling plate discipline, plus power, and a below average feel for contact. When he does connect, it tends to be loud. His best trait is defense where he's expected to be a comfortably positive contributor. The presence of Sean Murphy is only a temporary impediment – it's widely assumed the veteran Athletic will be traded over the winter.
Brayan Bello, 23, SP, BOS (MLB)
22 IP, 9.00 K/9, 4.91 BB/9, 7.36 ERA
Recently returned from the injured list, Bello had his best big league outing against the division rival Blue Jays. He tossed five innings of two-run ball while compiling seven strikeouts. Bello has a four-pitch repertoire led by a bowling ball 96.5-mph sinker. He also has a slightly harder fastball he can locate up in the zone. A slider and frequently-used changeup round out his pitch mix. In 18 minor league appearances he posted 12.10 K/9, 3.40 BB/9, and a 2.34 ERA. His carrying trait is an over-60 percent ground ball rate which, if maintained, would rank second among qualified starters between southpaw Framber Valdez (67.5%) and right-hander Logan Webb (58.4%). Like many sinker specialists making their debuts, Bello has struggled with free passes. He got away with iffy command in the minors because his stuff played even when thrown down the pike. He's liable to need an adjustment period in the Majors.
Five More
Mark Vientos, NYM (22): A possible alternative to Baty and Escobar, Vientos is red hot for the month of August. He's batting .403/.448/.661 with four home runs in 67 plate appearances. He draws negative reviews for his third base defense and is in the process of switching over to first base. The bat appears as if it should play in the Majors at either position, though he might be a tad ordinary at the cold corner. He's just shy of a 30 percent strikeout rate for a second consecutive season in the upper-minors.
Grayson Rodriguez, BAL (22): Rodriguez has been sidelined for nearly three months with a lat strain. He is due to face hitters in a simulated game later this week. It's possible he could make his debut in late-September.
Gunnar Henderson, BAL (21): Rumors abound of an impending callup for Henderson. Club officials are supposedly pondering the implications on his development. Henderson hasn't exactly knocked down doors in August, batting .259/.364/.435 with 12.1 percent walk and 31.3 percent strikeout rates.
Robert Hassell III, WSH (21): One of the prizes acquired for Juan Soto, the Nationals aggressively promoted Hassell to Double-A where he's hit .147/.237/.206 through his first eight games. Like Baty above, it's not uncommon for young players to scuffle when first presented with a new challenge. And even Mike Trout has eight-game slumps. Strikeouts have been an issue for Hassell since joining the Nats org.
Curtis Mead, TB, (21): Recently recovered from a month-long injury to his elbow, Mead has five hits and two walks over 14 plate appearances. The right-handed slugger could make a useful platoonmate with David Peralta, especially once rosters expand in a few days. He's Rule 5 eligible this winter so getting a jump on his service clock should be seen as acceptable – assuming the Rays can find a 40-man spot. He's hitting .299/.391/.536 on the year, mostly at Double-A.
Rays To Extend Tyler Glasnow
Rangers To Select Dallas Keuchel
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text:
Rahm Emanuel joins The Atlantic as contributing editor
By Joe Concha - 05/21/19 12:08 PM EDT
Rahm Emanuel has joined The Atlantic as a contributing editor, according to a Tuesday announcement from the former Chicago mayor.
Emanuel, who also served as chief of staff to then-President Obama from January 2009 to October 2010, will contribute "frequent essays to The Atlantic's Ideas section" per a statement from the 162 year-old publication.
Emanuel has written 13 articles for The Atlantic dating back to June 2017, including his latest piece, "It's Time to Hold American Elites Accountable for Their Abuses," which was published Tuesday.
The announcement comes after Lori Lightfoot was sworn in as Chicago's 56th mayor on Monday. Lightfoot, 56, is the first black woman and the first gay Chicagoan to lead the city.
Emanuel decided not run for re-election in last year's mayoral election as his approval ratings languished in the 30s.
The Daily Beast reported in November that Emanuel has also sat down with "top executives" at CNN and MSNBC about possibly joining as a pundit.
Tags The Atlantic Rahm Emanuel


text:
Mategnin est un hameau de la commune genevoise de Meyrin (Suisse). Le hameau se trouve à la frontière entre la France et la Suisse, près de Ferney-Voltaire.

Étymologie
En 1269, le hameau se nommait Matigniaco ou Matignins.

Ce nom d'origine burgonde pourrait dériver d'un primitif Matteningos (chez les Matteningi) dérivé du nom propre germanique Matto, la forme Matigniaco étant une latinisation abusive.

Notes et références

Liens externes

Localité dans le canton de Genève
Meyrin


Aren't these gorgeous? So simple to make too.
Just purchase some styrofoam balls and a spool of white sparkly pipe cleaners.
Simply start with making a hole and placing the end of the pipe cleaners in it.
Then holding the pipe cleaner in place, begin wrapping it around the styrofoam ball.
Before you know it, you'll have gorgeous Winter White Balls to sprinkle throughout your home.


text:
On Walls, Refugees and White Walkers
HOW WALLS MAKE US LESS SAFE
It's been a long couple of weeks, so I may have missed my opportunity to take advantage of the obligatory Game of Thrones reference on my blog. To what I think is my credit, the Mad Sociologist Blog hasn't really been on the GOT bandwagon. Four years ago I wrote a rather critical piece on the cultural response to Sansa Stark's rape. Aside from that and maybe a meme or two, the MSB has been GOT free.
This shouldn't be considered a rejection of the show as a cultural phenomenon. As it is with most things, I try to reserve commentary on this space for moments when I feel I have something to add that is not already being elaborated. When it came to the fictional Game of Thrones world, the real world did not lack for coverage. Even the Washington Post kept a graphic tally of deaths in Westeros.
The bottom line is that cultural phenomena like Game of Thrones become what they are because they resonate with the larger culture. Game of Thrones was a complex story-line with rich character development, but it also addressed themes that have resonance in our overall society, the distribution of power, the association of power and corruption, what it means to govern well, the influence of religion. Larger hidden themes have been identified as the threat of climate change and racism. Of course, the most explicit overlap between a central component of Westeros and the United States…
…the Wall.
In Westeros, the Wall served a very important function, it turned out. It was, in essence, the barrier between the living and a growing army of undead intent on destroying the living. In the context of the story, however, nobody really knew what The Wall was for. There were some myths and legends, but all the people of Westeros really knew is that they needed to guard it. It had been around for thousands of years and served the function of being the place where inconvenient people (bastards, criminals, traitors) were sent to get them out of the way.
Instead of a barrier between the living and the dead, it became a dividing line between the people of Westeros and the "Free Folk". The people of Westeros saw the Free Folk as barbarians, as Wildlings. The Free Folk saw the Westerosi as servile, slave minded people conditioned to "bend the knee" to the dominant king. The Wall made it possible to perpetuate this ignorance. After all, in metaphor, walls are recognized as barriers that keep people from getting to know each other.
In the United States, the debate is not about the value of a wall that existed for centuries, but rather building a wall where none ever before existed. The purpose is clear–brown people. Okay, that's not fair. The expressed purpose is to keep poor people from pouring into the nation, getting on our welfare rolls, selling us drugs, raping our women, spreading disease and taking all of our jobs.
Yeah. Like I said–it's about brown people.
The closing scene of season seven left us with an undead dragon (actually a Wyvern, but whatever) blasting a giant hole in The Wall, making it useless and allowing a vast horde of walking corpses to pour into Westeros.
By the end of the final season, one of the main characters turned his back on the "civilized" world and walked into the wilderness with his dog and his free-folk friend.¹ The Night's Watch was now an anachronism. The Wall was nothing more than half a barrier. So what does the future hold for such a world?
There are two options.
First, the hole in The Wall remains. If that's the case, the Westerosi and the Free Folk will interact. There will be conflict. There will be trade. There will be migration. There will be negotiation. New norms for interaction will have to develop. There will be rules about the miscegenation, rules about migrants joining one culture or another. Negotiations about established boundaries will have to take place. Let's face it, the Westerosi have a martial culture and will likely see opportunities for conquest north of what I guess we could call The Hole, or The Breach.² This may be especially true as the final scene of the series indicated a fertile future for the Free Folk–a green sprout growing from the once frozen ground. Winter is over.
The other option is to rebuild the wall, or to build some kind of barrier across The Breach. In my mind, the Free Folk have the greater incentive to do just that. However, we can't rule out the possibility of a new Night King rising north of The Breach and threatening humanity again. After all, the army of the dead had been defeated once before only to rise as a new threat.
So should we expect a "Sparrow" like movement in Westeros of red-hatted sycophants chanting "Rebuild the Wall!" "Rebuild the Wall!" as a rubber-faced demagogue pulls the strings of fear and resentment until they become reins of power?
It shouldn't surprise us if this becomes a subplot in some spin-off in the future.
The question then becomes, should the Westerosi rebuild the wall? After all, an army of the undead dedicated to the destruction of all living humanity is a pretty significant threat. It's an even greater threat than, say, desperate families fleeing drug cartels and oppressive poverty–though some might argue otherwise.
The answer in Westeros, as it is in the United States, is an emphatic "NO!" Even if there is an army of the dead, building a wall is not the strategy. To demonstrate this a simple mental experiment using the Game of Thrones world will suffice. The thesis is that the existence of The Wall only acted to make a bad situation worse.
Think about it. Let's say The Wall had never been built. There is no wall separating The Free Folk from the Westerosi. These two cultures would have interacted more, for better or worse. Perhaps one would have conquered the other. Maybe some kind of agreement would have been satisfied between the two, with some cultural overlap between the Free Folk and the people of The North. The Free Folk would likely have adopted some of the feudalism of the Westerosi. The people of the North would likely have adopted some of the democratic spirit of the Free Folk. Trade would have been established. Norms for group membership and interaction would have developed. Years of warfare may have even resulted in some clear boundaries, maybe some contested territory.
Regardless, there would have been regular contact between the Free Folk and the Westerosi.
Which means that the threat of the White Walkers would have been identified much much sooner than it was behind a wall. It would not have taken long for people to recognize the threat and to develop strategies for dealing with it well before it got out of hand. It's unlikely that the Night King could have raised such a vast army unnoticed if not for the existence of a seven hundred foot wall giving the Westerosi a false sense of security.
See, walls come with certain inherent weaknesses.
First, they set up barriers between people communicating and interacting with each other. This is the underlying problem of cultural ignorance. And ignorance can be dangerous when facing challenges that are global in scale. In the Game of Thrones world, the global threat was the White Walkers raising a growing army of the dead. In the real world, it's global climate change, global economic hegemony, nuclear proliferation and a growing refugee crisis. These problems cannot be solved by building walls. Indeed, they can only become worse when national cultures are shut off from each other.
Walls can be breached!
Secondly, walls can be breached. Those truly dedicated to breaching barriers will, over time, find a way. That means, walls can only give those who build them a false or, at best, temporary, security. Indeed, in concert with the ignorance instigated in the first flaw above, the existence of walls and the desire to overcome those walls, can create a power dynamic that becomes even more of a threat than the initial problem. We should remember this as the number of refugees on our border continues to grow, continues to become more desperate. Walls get breached.
Walls are never the answer to the problems faced by any given society. They may provide some temporary satisfaction for those so enclosed, but in allowing ignorance to spread and problems to fester, the ramparts of security can quickly become a prison, and a strategy of defense can become the very weakness causing collapse.
If we are to face the very real challenges of our day, we must do so cooperatively with all of the world. We must find ways of bridging our differences, defining the problems, framing our interests and securing solutions. This cannot be done with walls.
I am not among those disappointed with the ending of Game of Thrones. I'm perfectly satisfied with Dani turning evil–power corrupts. I'm satisfied with Sansa being the queen of the North. She's the most competent leader, but didn't belong in King's Landing. I'm fine with Bran being the King of the Six Kingdoms–hey, who's more qualified than the guy who knows everything. I am most satisfied with Jon's ending. I've always been on Team: Jon Tells Everyone to Suck it and Runs off with his Dog and the Free Folk.
An open letter to George R. R. Martin: Feel free to use any of the ideas above. I don't mind…oh…wait…you actually have to finish the series first. Never mind. An open letter to whoever is contracted to capitalize on the Game of Thrones Franchise: Feel free to use any of the ideas above. I don't mind. Just be sure to include a bearded Maester with an acute sociological imagination. I'm aware that he will almost certainly have to be beheaded, but that's the nature of the discipline.
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Great blog, Andy. Thanks so much for the exposure you give our organization. It greatly enhances our ability to carry out our mission of honoring our Veteran Heroes.
I thank you and all of Honor Flight for all that you do.


text:
Books are lighthouses erected in the great sea of time. ~E.P. Whipple
Buzzing About Books
Daily Buzz
Tag Archives: Melissa Tagg
#BookReview: All This Time by Melissa Tagg
All This Time is a story I've anticipated since the moment Raegan and Bear appeared on the page. Beautifully rendered, their emotional journey is tender and touching and not soon to be forgotten! Tagg's characterization is exceptional, as she has crafted a fictional family that very much comes to life in the mind of the reader. I love the charm of Maple Valley and revel in the Walker's camaraderie! While I lament the end of this wonderful series, it is certain to remain one of my very favorites.
I received a complimentary copy of this book. No review was required, and all thoughts expressed are my own.
Bear McKinley's past refuses to let go.
Ten years ago, Bear gave up everything-his freedom and his reputation-for his mess of a family. But after years of distance and too many attempts at starting over, he finally has a new life doing noble work in Brazil . . . until his past catches up to him once again. Suddenly he finds himself back in Maple Valley, charged with the care of his missing brother's children, convinced he's out of second chances to make his life count. And yet, with every day that passes, these kids, this quirky town and the woman he never stopped missing help patch the holes in his heart. Maybe this is the fresh start he's been longing for all along. But as his newfound hope grows, so does the mystery surrounding his brother's activities-and when the threat reaches into the lives of those he loves, it's clear he can't run away this time.
Fear holds Raegan's future captive.
Raegan Walker is fine. She's happy working a slew of part-time jobs, still living in her childhood bedroom and rarely venturing from her hometown. At least, that's what she tells everyone . . . and herself. But she can't help wondering what might've happened if she hadn't abandoned her art so many years ago-and if Bear McKinley had never left. When Bear returns and she's commissioned for a painting that just might revive her artistic ambition all in one week, it's time to finally reach for more than fine. But doing so means facing the fears that have held her back all this time, including admitting the secret she's kept from Bear and her family. With her dream and her heart on the line, how much will Raegan have to risk to finally chase her happy ending?
Learn more about the book and the author.
Tags: #BookReview: All This Time by Melissa Tagg, All This Time, Buzzing About Books, Contemporary fiction, Contemporary romance, Inspirational fiction, Melissa Tagg, Romance, Walker Family series
Categories Books, Reviews
Friday Freebie: One Enchanted Christmas by Melissa Tagg
One Enchanted Christmas by Melissa Tagg
Download your FREE copy here: http://amzn.to/2gsNSow
Last December, mystery author Maren Grant had the most perfect night of her life. On a glimmering winter evening, she got to watch the photo shoot for her very first book and ended up on a magical date with the cover model himself—Colin Renwycke.
Fast forward one year. This December, with a looming deadline, restless spirit and her creative spark long since gone, Maren is desperate to get unstuck. And she can't get Colin out of her head…or his year-old open invitation to spend a couple weeks writing at his family's farm.
Drew Renwycke never planned to come home and take over the Renwycke family farm. But he's spent too many years watching his siblings unravel, including his brother, Colin, after one terrible family mistake. If moving to Maple Valley, Iowa, renovating an old farmhouse and switching careers is what it takes to put the Renwycke family back together, he'll do it.
But his simple plan upends when a scrappy author lands on his doorstep. And she just might be the key to coaxing his brother home. But what if he wants her all to himself? Drew will have to choose between his Christmas wish and the enchantment of a holiday romance that just might be the happy ending they all long for.
Tags: Buzzing About Books, Christmas, Christmas romance, Christmas story, Contemporary fiction, Contemporary romance, Free book, Free download, Free e-book, Friday Freebie, Friday Freebie: One Enchanted Christmas by Melissa Tagg, Inspirational fiction, Melissa Tagg, Novella, One Enchanted Christmas, Romance, Romantic comedy
Categories Books
$0.99 Sale- One Enchanted Eve
All the ingredients for an enchanting happily ever after!
Melissa Tagg's One Enchanted Eve is out today, and it's only 99¢ for a limited time! Purchase a copy: http://amzn.to/2eUjNfW
After years of mistakes and regret, Colin Renwycke finally has a plan: Hone his baking talent at the Denver Culinary Institute and embark on a new career as a pastry chef. If he's lucky, he might even manage to earn back his family's respect. But despite his skills in the kitchen, Colin's a mess in the classroom and his ongoing disasters are proving too much for his prickly instructor. If he loses his spot at the school, he's out of backup plans.
Culinary school instructor Rylan Jefferson has the chance to reclaim her dream of running her own bakery. But she only has until Christmas Eve to come up with the perfect recipe to impress an eccentric investor. She has no time for holiday parties or family plans . . . and especially not for the unruly student baker who couldn't follow a recipe if his life depended on it.
But Colin has the one ingredient Rylan needs most—talent. Lots of it. And when he makes a proposal that just might solve both their problems, Rylan can't say no—even if it does mean traveling all the way to Iowa. It just might be that the snow-covered plains and a charming small town full of postcard Christmas cheer are exactly what her hungry heart needs . . . along with a man who is much more than he seems.
Tags: $0.99 sale, $0.99 Sale- One Enchanted Eve, Buzzing About Books, Christmas, Christmas story, Contemporary fiction, Contemporary romance, E-book sale, Holiday story, Love story, Melissa Tagg, Novella, One Enchanted Eve, Romance, Sale
#BookReview: Keep Holding On by Melissa Tagg
Keep Holding On by Melissa Tagg
Purchase a copy: http://bit.ly/2emqasL
Beckett Walker hasn't stepped foot in Maple Valley in years. There's no getting past the painful memories, and there's every chance he'll be arrested as soon as he shows his face. Which is exactly what happens when he finally returns. Suddenly his dream of adventure as a military lawyer comes skidding to a halt.
Horticulturist Kit Danby has spent too much time missing home and her childhood best friend–Beckett Walker. Now she might have a shot at reclaiming both. After years of living abroad, she returns to run her family's apple orchard. She has one season to turn a profit and impress the father she barely knows. But she can't do it alone.
It should be simple: Beckett needs community service hours. Kit needs a helping hand. But there's more at stake than either of them planned. With a tangled past and futures that look nothing alike, they'll have to find a way to weather the storms of the present . . . or risk losing everything.
The Walker family is one of my very favorite fictional families, and I love spending time with them in Maple Valley! Full of charm, Keep Holding On delighted me from the first word until the last. I adored the wit and humor of Kit and Beckett's story, as well as the wonderful wisdom that is woven through its pages. The orchard, Willa, and a baby goat were also among my favorites, but you'll have to read the book to find out more. Dramatic and romantic, Keep Holding On is a must-read romance!
Melissa Tagg is a former reporter and total Iowa girl. In addition to her homeless ministry day job, she's also the marketing/events coordinator for My Book Therapy, a craft and coaching community for writers. When she's not writing, she can be found hanging out with the coolest family ever (not that she's biased), watching old movies, and daydreaming about her next story. She's passionate about humor, grace, and happy endings.
Melissa blogs regularly and loves connecting with readers at http://www.melissatagg.com.
Tags: #BookReview: Keep Holding On by Melissa Tagg, Buzzing About Books, Contemporary romance, Inspirational fiction, Keep Holding On, Maple Valley, Melissa Tagg, Romance, Walker Family series
#BookReview: Like Never Before by Melissa Tagg
Like Never Before by Melissa Tagg
Amazon | Barnes and Noble | Christianbook | DeeperShopping
Maple Valley became Amelia Bentley's haven after her heart and her dreams of a family were shattered. But her new life as a newspaper editor is shaken when the small-town paper is in danger of closing. Her one hope: A lead on an intriguing story that just might impress the new publisher…if only she new who he was.
After his biggest campaign success yet, widowed speechwriter Logan Walker now has the chance of a lifetime–a spot on a presidential campaign. But his plans are interrupted when he finds out he's inherited his hometown newspaper. He travels home intent on selling the paper and spending some much-needed time with his young daughter before making the leap into national politics.
But instead of a quick sale and peaceful break from his hectic career, Logan finds himself helping Amelia chase her story. She's scrappy, but wounded. He's dependable, but lost. They may butt heads more than expected, but a series of leads on Maple Valley's quirky unsolved mystery is just the start of the sparks that fly in the office and in their hearts.
Like Never Before is a must-read romance! Melissa Tagg's trademark humor and wit shine as she brings Logan and Amelia's story to life.
From the email banter that begins the novel to the sigh worthy ending, each and every word is pure delight. Speaking of words, here's one for you – LOGAN. Be still my heart! I love this guy who sees Amelia for who she really is. "I just think one person seeing you for who you really are is better than 150,000 people who've got it wrong."
Humorous and heartfelt, Like Never Before is a novel that is equal parts entertaining and encouraging! The charm of Maple Valley and its residents swept me into the story and Amelia and Logan engaged me with every turn of the page. I reveled in the unexpected historical mystery that threads its way through the novel and savored the inspirational insights that were shared.
From the moment I met them, the members of the Walker family leapt straight from the pages and into my heart. "They are one of Maple Valley's staple families- the kind everyone loved and not-so-secretly wanted to be a part of." I adored Like Never Before and can't wait to continue this fantastic series!
I received a complimentary copy of this book in exchange for an unbiased review. All thoughts expressed are my own.
Tags: Buzzing About Books, Contemporary fiction, Contemporary romance, Inspirational fiction, Like Never Before, Maple Valley, Melissa Tagg, Romance, Romantic comedy, Walker Family series
Release Day #Giveaway from Melissa Tagg!
Hi, friends! Melissa Tagg is celebrating the release of her fourth novel with a giveaway you don't want to miss! If you follow Melissa on social media, you know she's been gushing about Logan Walker for a long time now! 😉 Head over to her blog and read more about why she really loves this character and enter to win a copy of Like Never Before, plus a $25 Visa card!
Tags: Buzzing About Books, Contemporary romance, Giveaway, Inspirational fiction, Like Never Before, Melissa Tagg, Release Day Giveaway, Walker Family series
Categories Books, Giveaways
#BookReview: One Enchanted Christmas by Melissa Tagg
Amazon | Barnes and Noble
Adorable! Bubbly! Charming! Delightful!
I'm pretty sure I could continue through the alphabet listing adjectives to describe this holiday novella. I loved it! All of the story elements, from the narration to the cover model crush to the trip Maple Valley, were such fun, and the romance was enchanting!
One Enchanted Christmas is the perfect read for the holiday season; it's guaranteed to bring a smile to your face and joy to your heart!
Tags: #BookReview: One Enchanted Christmas, Buzzing About Books, Christmas, Contemporary fiction, Contemporary romance, Holiday romance, Love story, Melissa Tagg, Novella, One Enchanted Christmas, Romance
#BookReview: Courting Mr. Emerson by Melody Carlson
#BookReview: Almost Home by Valerie Fraser Luesse
#BookReview: Tomorrow's First Light by Naomi Rawlings
#BookReview: The Sky Above Us by Sarah Sundin
#BookReview: Never Let Go by Elizabeth Goddard


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