This is the first Protei which has an Android phone on board - extending its computational power and bringing it a step closer towards autonomous navigation. A laptop sends commands to the Phone via a server and the phone is connected to an Arduino Uno, which controls the motors, via Bluetooth.
The Protei App facilitates communication between the server and Arduino. The App connects to the Arduino via Bluetooth and recieves/sends commands to the server via MQTT. In addition to this, it also computes the position of the Sail and the Rudder, displays the latest message exchange and the orientation of the boat (Gyroscope).


"A Taste of Noi Thai"
A 4-piece box set of signature boutique chocolates will be gifted to each couple, with mention of Hy's participation in Restaurant Week Hawaii. Includes our Cherries Jubilee, Bananas Foster, and Hy's labeled truffles.
Offer valid during Restaurant Week Hawaii only.
Hy's Steak House, well known local steak house in Hawaii, has been a tradition in Waikiki for more than forty years and continues to be a fovorite with visitors and locals alike.
Aloha & welcome. We are an artisanal noodle, nabe and small plate concept from Japan. "Nojo" means farmer in Japanese and we proudly source as many ingredients as we can locally. We pride ourselves on the freshness of our foods and curating them from the bounty the Hawaiian Islands have to offer.
Ed Kenney's Mahina & Sun's is a purveyor of elevated home cooking inspired by Hawaii's people and place. Our menus offer unique local dishes and cocktails that utilize only the very best ingredients from Oahu's farmlands - for brekkie, lunch, dinner and drinks. We're also the state's leader in ocean-friendly sourcing practices.
With nightly live music, occasional poolside concerts, and movie screenings under the stars, Mahina & Sun's is much more than a meal. It's a place where adventurers gather, where new connections are made, and where ideas are inspired, all over food and drink you can feel good about. Hidden within a swell little spot called the Surfjack Hotel & Swim Club, Mahina & Sun's participates in a creative space that connects local and visitors to exciting Honolulu artists, designers, musicians and epicureans.
A concept of esteemed Chef Ed Kenney, Mahina & Sun's is Kenney's fourth establishment - following Town Restaurant, Mud Hen Water, and Kaimuki Superette - and his only eatery in Waikiki.


Sizing tips - How to choose the right size. This bracelet comes in one size (approx 7.75 inches), which should fit most teens and ladies. It is meant to be worn loose, like a bangle, and can be gently shaped into an oval if you prefer by squeezing to fit your wrist.
Taking care - To keep your bracelet looking its best, just wash it gently with water, and dry with a soft cloth.


text:
Lophocampa caryae ist ein Schmetterling (Nachtfalter) aus der Unterfamilie der Bärenspinner (Arctiinae). Das Artepitheton bezieht sich auf Hickorygewächse (Carya), die Hauptfutterpflanzen der Raupen. Die Art wird im englischen Sprachgebrauch als Hickory tussock moth bezeichnet.

Merkmale

Falter
Die Falter besitzen eine Flügelspannweite von 37 bis 55 Millimetern. Ihre Vorderflügeloberseite hat eine gelbbraune Grundfärbung, die mit einer weißlichen Fleckenzeichnung überzogen ist. Die Hinterflügeloberseite ist zeichnungslos weiß. Am Kopf hebt sich ein brauner Haarschopf in Form eines Dreiecks ab. Der dünn behaarte Thorax ist kräftig gelb gefärbt.

Raupe
Die Raupen sind dicht weißlich behaart. Auf jedem Rückensegment befinden sich kurze schwarze Haarbüschel, an den Seiten schwarze Punktwarzen. Hinter dem Kopf sowie am Körperende heben sich zu jeder Seite schwarze oder weiße aus wenigen sehr langen Haaren bestehende Haarbüschel ab. Die Raupenhaare können beim Menschen zu stark juckenden Hautreizungen und Allergien führen, die zuweilen eine medizinische Behandlung notwendig machen.

Verbreitung und Vorkommen
Die Art ist im Osten und Südosten Nordamerikas von Nova Scotia in südlicher Richtung bis in den Norden Floridas weit verbreitet, in Texas kommt sie vereinzelt vor. Sie lebt bevorzugt in Nussbaumhainen und lichten Laubwäldern.

Lebensweise
Die tagaktiven Falter fliegen in einer Generation im Mai und Juni. Nach der Befruchtung legen die Weibchen die Eier in großen Spiegeln ab. Junge Raupen leben zunächst gesellig, später einzeln. Sie ernähren sich von den Blättern unterschiedlicher Bäume, dazu zählen in erster Linie Hickoryarten (Carya) sowie weitere Walnussgewächse (Juglandaceae). Zuweilen wurden sie auch an Eschen- (Fraxinus), Ulmen- (Ulmus),  Ahorn- (Acer) und Eichen-Arten (Quercus) gefunden. Sie nehmen während der Entwicklung Giftstoffe aus den Blättern auf, sodass sie für potentielle Fressfeinde ungenießbar werden. Die Art überwintert als Puppe in einem Kokon zwischen Blättern.

Weblinks

 eol.org – Encyclopedia of Life

Einzelnachweise

Bärenspinner
Arctiinae
Wikipedia:Artikel mit Video

redpajama_set_name: RedPajamaWikipedia


How would your other half react? Would she laugh it off with a "boys will be boys" attitude? Or would she, as one bride-to-be did after watching a tape, lunge for her man, chase him out of the house, wrestle him to the ground with cries of "you said you loved me", then head straight to the garage for a baseball bat as her aunties turn up with wooden spoons to help?
Camera crew at a stag do? Baaaad idea. Though surfing You Tube for some of the show's clips would be recommended.


This enchanting property is nestled on a gorgeous, fully fenced 4601m2 block in a premier position with dual street access (front and rear of the property) and is an outstanding example of acreage living in Park Ridge South.
In summary, 10 Batavia Court, Park Ridge South is a 3 bedroom house in Park Ridge South with 1 bathrooms, 6 car spots and is for sale by All Properties Group - BROWNS PLAINS. Please use the contact form or call an agent to arrange an inspection.
Can I afford 10 Batavia Court?
Measure up how the 'pocket' around 10 Batavia Court, Park Ridge South measures up to the rest of Park Ridge South before buying it. Get a feel for your new neighbours and get an idea of how well you'll fit in here. If you are looking to invest here and rent it out, you can get a detailed idea of other rentals in the area and an idea of how much others are renting theirs out for. Perhaps you could get a similar price.


The Vatican announced on Friday four new staff additions to the Holy See Press Office, appointments which add further pieces to the puzzle of Greg Burke's and Paloma Garcia Ovejero's sudden and largely unexpected departures on New Year's Eve.
That began with the appointment Dec. 31 of a replacement for Burke in the person of ad interim director Alessandro Gisotti, and has now been followed by the naming yesterday of a senior advisor to the director, French journalist Romilda Ferrauto, and two assistants: American Sister Bernadette M. Reis, FSP, and Peruvian journalist Raúl Cabrera Pérez. South Bend native and former official at the Pontifical Council for Social Communications, Thaddeus Jones, will also join the press office team as office manager.
All have worked at one time or another for Vatican Radio, and having known most of them for many years, they are very able, fair-minded and personable professionals with a love for the Church.
This alluded to the fact that the Pope was already putting together a new communications office, but Burke and Garcia increasingly didn't feel a part of it. The two former Rome correspondents had been suffering under a very heavy workload, and for months had been pleading with the Vatican for more staff but to no avail.
The Register has learned that for at least six months, Burke had specifically asked nearly a dozen times for Jones to be hired, but each time his requests were turned down. Even when one of them inquired earlier this week whether Jones would be joining the press office, they received a negative response.
The Register has asked the Press Office if they could explain the reasons for the timing of the new appointments, and why they were not made during the tenures of Burke and Garcia, but so far have not received a reply.
Yet the new appointments add further weight to the fact that Burke and Garcia were increasingly not being given the support they needed. Sources say they had little or no access to the Pope, and that the running of the Vatican was increasingly "chaotic" with everyone wanting to have a say in strategy.
The internal problems were visible to us in the press corps in the form of a lamentable Vatican silence at a time of crisis.
It wasn't always so dysfunctional. Burke, a former Rome correspondent for Fox News and the Register, had been part of the Secretariat of State since 2012 as a special communications adviser before Pope Francis hired him on the recommendation of Ruffini's predecessor, Msgr. Dario Edoardo Viganò.
Within the Secretariat of State, Burke had worked closely with Archbishop Peter Wells, an Oklahoma native and then-assessor of general affairs in the Secretariat of State, and Cardinal Angelo Becciù, the sostituto (deputy) to the Secretary of State.
But in recent years, the Secretariat of State has gradually lost its grip on Vatican communications with power steadily transferred to the Dicastery for Communication and, more importantly, the Pope's inner circle of advisers.
Since taking up his post, Burke had become increasingly isolated: Archbishop Wells left shortly before Burke's appointment as press office director, Cardinal Becciù was appointed prefect of the Congregation for the Causes of Saints last summer, and Msgr. Viganò left following the "Lettergate" affair last March, although continues to wield influence as assessor in the Dicastery for Communication.
At the same time, "unofficial" spokesmen close to Francis, such as Vaticanistas Andrea Tornielli, Gianni Valente and Jesuit Father Antonio Spadaro, were seen as undercutting Burke's work, as has been widely reported. Ruffini's appointment and his subsequent prominence during the media briefings at the October Youth Synod further undermined Burke's position, while the coup de grâce was Tornielli's appointment last month as Vatican Media's editorial director.
Added to the difficulties was Pope Francis' working relationship with his spokesman. He and Burke appeared to have a good rapport, but informed sources say it was only so deep, and was hindered by the Pope's well-known disregard for the United States and his lack of trust in general. The decision to give Ruffini prominence at the synod briefings was the Pope's, sources say, despite Francis telling Burke he would be given all the authority he needed as press office director.
From all the above, it appears the Vatican's problem has been not one of poor communications so much as poor management — as has often been the case throughout its history. Perhaps with this new structure finally in place, that will now begin to change, and the direction the Pope is leading the Church become more transparent.


text:
Nordhaugen Hill är en kulle i Antarktis. Den ligger i Östantarktis. Norge gör anspråk på området. Toppen på Nordhaugen Hill är  meter över havet.

Terrängen runt Nordhaugen Hill är platt åt nordost, men åt sydväst är den kuperad. Den högsta punkten i närheten är Austkampane Hills,  meter över havet,  km sydväst om Nordhaugen Hill. Trakten är obefolkad. Det finns inga samhällen i närheten.

Kommentarer

Källor

Kullar i Östantarktis
Norges anspråk i Antarktis
Berg i Antarktis 500 meter över havet eller högre


Damon Salvatore - Tragic Hero. Lyrics from the song Tragic Hero দ্বারা Funker Vogt.. Wallpaper and background images in the ডামন্ স্যালভ্যাতরে club tagged: damon salvatore the vampire diaries funker vogt.
i like it, but is it suposed to be a poem?


text:
VOTD: T.Shirt's Music Video "24 Frames"
By Peter Sciretta/March 4, 2011 5:00 am EST
Over 120 film titles are included in the music video for rap artist T.Shirt's song "24 Frames", which plays out in one-shot, features a cast of 30 friends, and travels through 2 floors of a movie theater in SoHo. Watch it now embedded after the jump.
via: HighDef

redpajama_set_name: RedPajamaCommonCrawl


Total Mintage Of Only 830!
For almost all of human existence, humans have enslaved other humans physically. When that ended, a new form of human slavery became even more pernicious, debt slavery.
Power shifted from warlords, generals and politicians to the hidden bankster. These banksters move quietly behind the scenes backing all sides of their rigged game, all the while counting their profits.
Silver remains the most pure way of cleansing this system, by using their debt based, ponzi fiat to stack real, tangible wealth outside of their system of debt and death.
Will the Death of the Dollar be the conscious crisis to end all debt slavery or will it be the start of an even more evil Mark of the Beast?


Ashley contacted me to capture a Chicago lifestyle session, her getting ready for her thirtieth birthday with her husband. They got ready at the Woldorf Astoria, Chicago and later headed out to Alinea. I captured some quick images of Ashley applying her makeup in the hotel, then some images of her and her husband in the room. It was so cute, her parents got her the room as a gift!
Later we went down to the outside sidewalk of the hotel and I captured some full-length photos of her dress front and back and some headshots. How beautiful was her dress from self portrait?! We then walked into the lobby and I captured some quick photos of her and her husband. Altogether our session was only 30 minutes, but we sure got a lot captured of her beautiful night! Thank you Ashley for a fantastic shoot & enjoy your thirties.


« Help the CofCC cope with the postage increase.
Any objective observer of last night's GOP debate can't deny that Fox News is Unfair and Unbalanced after last night. Whatever presence to fairness was shattered by their treatment of Ron Paul after the debate. Carl Cameron and other reporters seemed genuinely shocked that Ron Paul could be doing so well in the post-debate polling. Fox News is clearly rooting for the Establishment 3 of Rudy Guiliani, John McCain, and Mitt Romney. Now however, the ones who really matter, the voters, are signaling their wish for true change. Rudy Guilianni is like George Bush, a liberal sleeper. John McCain's sponsorship of amnesty and his political pandering on the Confederate flag show that he is no politician of principle. Mitt Romney is a repackaged Republican version of John Kerry.
The Republican Party is now committing the same ideological purge the Democrats attempted to engage in last fall with the primary challenge to Joe Lieberman in Connecticut. The incomparable Ron Paul said something that ranks as heresy in the Republican Party and especially among neo-conservatives. It is that America's foreign policy provoked the September 11, 2001 attacks on our country. Rudy Guilianni was apoplectic. How could one dare suggest such a thing? He had never heard of such an explanation. Apparently he had not read Usama Bin Laden's 1998 fatwa in which Al Qaeda declared war on the United States. Guilianni must also have never read Pat Buchanan's commentary and books. Whether you agree with Dr. Paul or not, we can all agree on his right to articulate this position. Yet now the same Michigan GOP that ran away from the Michigan Civil Rights Initiative last fall (and got royally trounced as a result) has it's chairman, Saul Anuzis, clamoring to get Ron Paul barred from all future GOP debates!
This is perhaps the biggest attack on free thinking in a GOP primary that we have witnessed. Dr. Paul is one of only a choice few Republicans whom is right on the immigration issue. He also is a very unique candidate in his approach to issues. If the GOP bars him from future debates then the GOP is no different from the Democrats. Everyone must tow the party line and cowtow to the conventional wisdom. Well this conservative doesn't think so. Whether it's Dr. Paul, Tom Tancredo, or Duncan Hunter, we need someone who will shake up Washington and not tell us what we want to hear and then betray us (ahem George W. Bush/John McCain).
Perhaps the best illustration of why Dr. Paul is shaking things us was his confrontation with Sean Hannity after the debate. The fact that the GOP's favorite cheerleader couldn't explain why even after Paul's comments on foreign policy, that Paul was winning the post debate polling is telling. Since they can't explain it, now they want to shut Ron Paul up. If Ron Paul is silenced, how much longer till we are silenced. With hate crimes legislation weeding it's way through Congress this is a fair question. We are Americans, not Soviets or Nazis. Someone needs to make sure the GOP gets the memo.
This entry was posted on Friday, May 18th, 2007 at 8:43 am and is filed under Uncategorized. You can follow any responses to this entry through the RSS 2.0 feed. Responses are currently closed, but you can trackback from your own site.


text:
How the South Tyneside Council leader kept his community centres open
South Tyneside Council leader Iain Malcolm spoke with Emily Rodgers for the new PSE podcast about how he found a solution for his residents in the face of budget cuts.
Iain Malcolm has been a member of South Tyneside council since 1988 and leader for the past ten years. Over that time, he has seen the budgets cut "systematically year on year" whilst also noticing an increase in demand to council services.
Speaking on the PSE podcast back in October, Malcolm said that in some cases his staff are doing "30% more with 30% less".
South Tyneside Council is the third worst hit authority in England in terms of budget cuts from central government but has still been able to deliver award winning services for its residents and become co-operative council of the year.
Iain credits his residents as the driving force behind his successes and describes them as "close knit community" who were ready to step up to the plate.
Instead of closing the 19 community centres and libraries in the area, they asked the management committee to take ownership in running the community centre and transfer the asset to them for day to day running.
By giving the control of children's centres, community centres and libraries to the residents, they were able to enjoy a better tailored service that works specifically for them.
They get support from the corporate centre, but they are able to decide how best to run them within the community.
Another added bonus is as they fall outside of the council remit, they can apply for funding from elsewhere, for example one local community centre got over half a million pounds from the Lottery for a centre expansion.
Volunteers, supported by corporate centres are running the libraries and managing to run activities and coffee shops along side it, something the council would not have been able to do.
Council leader, Iain Malcolm said:
"I think sometimes councils can be reluctant at looking at the Asset Transfer Programme and what I would say is no one size fits all, it works for us because we've got a close-knit community who value local community centres and want them to work.
"That may not be the case in every area but it was in ours, and I will say that no council should be concerned about community engagement, we represent the residents and it's about empowering them to take ownership of some aspects of community life more so than running their local community."
Date of interview: Oct 22 2019
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text:
import json

from dojo.models import Finding

class ESLintParser(object):

    def get_scan_types(self):
        return ["ESLint Scan"]

    def get_label_for_scan_types(self, scan_type):
        return scan_type  # no custom label for now

    def get_description_for_scan_types(self, scan_type):
        return "JSON report format"

    def _convert_eslint_severity_to_dojo_severity(self, eslint_severity):
        if eslint_severity == 2:
            return "High"
        elif eslint_severity == 1:
            return "Medium"
        else:
            return "Info"

    def get_findings(self, filename, test):
        tree = filename.read()
        try:
            data = json.loads(str(tree, 'utf-8'))
        except:
            data = json.loads(tree)

        items = list()
        for item in data:
            findingdetail = ''

            if (len(item["messages"]) == 0):
                continue

            for message in item["messages"]:

                if message["message"] is None:
                    title = str("Finding Not defined")
                else:
                    title = str(message["message"])

                if message["ruleId"] is not None:
                    title = title + ' Test ID: ' + str(message["ruleId"])

                findingdetail += "Filename: " + item["filePath"] + "\n"
                findingdetail += "Line number: " + str(message["line"]) + "\n"

                sev = self._convert_eslint_severity_to_dojo_severity(message["severity"])

                find = Finding(title=title,
                            test=test,
                            description=findingdetail,
                            severity=sev.title(),
                            file_path=item["filePath"],
                            line=message["line"],
                            url='N/A',
                            static_finding=True,
                            mitigation='N/A',
                            impact='N/A')

                items.append(find)
        return items

redpajama_set_name: RedPajamaGithub


text:
Offenses Handled
Courts Served
Jonathan F. Marshall
Brett Rosen
Colin E. Bonus
Jason Seidman
William Wachowski
Thomas Huth
Matthew Dorry
Paul Koutouzakis
James Fagen
Abraham N. Basch
Brian McCauley
Over 200 Years Combined Experience Handling Criminal Charges
Former County Prosecutors & Municipal Prosecutors On Staff
Certified Criminal Trial Attorney, 10 Attorneys Practicing Exclusively Criminal Defense & DWI
Convenient Bergen County Office Locations in Fort Lee, Hackensack & Paramus
Bergen County Criminal Defense Attorneys
Over 200 Years Combined Experience Handling Criminal Charges in Bergen County | Former Bergen County Prosecutors & Municipal Prosecutors in Major Towns On Staff | Certified Criminal Trial Attorneys, 10 Attorneys Practicing Exclusively Criminal Defense & DWI | Convenient Bergen County Office Locations in Fort Lee, Hackensack & Paramus
CALL NOW FOR A
Marijuana Possession Lawyer in Bergen County NJ
Marijuana Possession Lawyer in Bergen County NJjmarshall2021-02-17T15:33:06+00:00
Fort Lee NJ Marijuana Possession Lawyers
Possession of Marijuana is one of the most common drug related charges issued by police officers in Bergen County. As you will see below, the applicable penalties for anyone convicted of possession of marijuana will depend on the actual quantity of marijuana possessed and your proximity to certain areas. A conviction for even a small amount of marijuana can have devastating consequences on you or your loved one's future. The Law Offices of Jonathan F. Marshall has been representing individuals charged with possession of marijuana, possession of cocaine, possession of heroin and possession of prescription drugs in towns throughout Bergen County, including but not limited to Fort Lee, Hackensack, Paramus, Fair Lawn, Saddle Brook, Ridgefield Park, Englewood, Elmwood Park, Rochelle Park, East Rutherford and Central Bergen Municipal for over fifteen (15) years. Our firm will defend you or your loved one's marijuana charges since we have:
Over two-hundred (200) years of combined experience
A team of ten (10) criminal defense attorneys that devote their entire practice to criminal law
Our firm has seven (7) former prosecutors
Three (3) of our attorneys were former county prosecutors and held directorial positions of the Drug, Gang, and Gun Task Force, Major Crimes Division, Trial Division, Juvenile Division
Three (3) of our attorneys were former municipal prosecutor in over twenty-five (25) towns
One (1) of our attorneys is Certified by the Supreme Court of New Jersey as a Criminal Trial Attorney, a distinction held by less than 1% of attorneys in this State
One (1) of our lawyers was recently selected to Super Lawyers Rising Stars 2020 list for New Jersey which is a highly credentialed, peer-influenced, third-party validated, and a patented process that only 2.5% of the attorneys in this New Jersey are selected to this list
Selected to the National Trial Lawyers Top 100 and Top 40 Under 40
Selected to the 10 Best Law Firms in New Jersey for Client Satisfaction by the American Institute of Criminal Law Attorneys
If you or someone you know has been charged with unlawful possession of marijuana in Bergen County, please contact any one of our three (3) Bergen County offices in Hackensack, Paramus, and Fort Lee immediately for a free initial consultation about you or your loved one's pending charge(s) at 201-429-9783.
Marijuana Charges in NJ:
Simple Possession: Under 50 grams of Marijuana
Possession of Marijuana over 50 grams
Possession with Intent to Distribute Marijuana
Possession with Intent within 500 ft of a Park / Public Housing
Possession with Intent within 1000 ft of a School zone
Possession of a Controlled Dangerous Substance in Motor Vehicle
As you can see, there is a wide range of potential charges related to this charge. What you are charged with will typically depend on the amount of marijuana possessed, your proximity to a school, public park or housing project and whether or not you were arrested with some form of drug paraphernalia which suggests that you possessed the said drugs with intent to distribute. In addition, with the sudden rise in synthetic marijuana, the legislatures have drastically increased the penalties for anyone convicted of either possessing synthetic marijuana or possessing synthetic marijuana with the intent to distribute.
Paramus NJ Marijuana Possession Attorneys
Elements of the Offense: Possession of Marijuana: N.J.S.A. 2C:35-10A(4)
The criminal charge for possession of marijuana in New Jersey is set forth in N.J.S.A. 2C:35-10, which provides in pertinent part that:
It is unlawful for any person, knowingly or purposely, to obtain, or to possess, actually or constructively, a controlled dangerous substance or controlled substance analog, unless the substance was obtained directly, or pursuant to a valid prescription or order form from a practitioner, while acting in the course of his professional practice, or except as otherwise authorized. Any person who violates this section with respect to: Possession of 50 grams or less of marijuana, including any adulterants or dilutants, or five grams or less of hashish will be charged with a disorderly person offense.
Grading of the Offense & Applicable Penalties:
Possession of marijuana less than 50 grams is a disorderly person offense and if convicted the defendant can face up to six months in jail, a $1000.00 fine and a potential two year loss of license.
Possession of marijuana more than 50 grams but less than one ounce is a crime of a crime of the fourth degree (felony) and if convicted the defendant can face up to eighteen months in jail and a potential two year loss of license.
Possession of marijuana more than one ounce or more but less than five pounds is a crime of the third degree (felony) and if convicted a defendant can face up to five years in state prison, a fine up to $25,000.00 and a potential two year loss of license.
Possession of marijuana more than five pounds but less than 25 pounds or more than 10 but fewer than 50 marijuana plants, regardless of weight, is a crime of the second degree (felony) and if convicted the defendant can face up to ten years in a state prison and a potential two year loss of license.
Possession of marijuana more than 25 pounds or more than 50 marijuana plants is a crime of the first degree (felony) and if convicted the defendant can face up to twenty years in a state prison, a fine up to $300,000.00 and a potential two year loss of license.
Criminal Defense Lawyer in Hackensack NJ
As you can tell the applicable penalties for anyone convicted of this charge can range drastically depending on the circumstances surrounding the charges. The Law Offices of Jonathan F. Marshall is available 24/7 to answer any questions or concerns you may have regarding your pending charges. Please feel free to contact any one of our Bergen County offices for a consultation at 201-429-9783.
Our Fort Lee Office
Our Hackensack Office
Our Paramus Office
Bergen County Arrests & Criminal News
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Fort Lee Office
1 Bridge Plaza, Suite #275
Fort Lee, NJ 07024
Hackensack Office
411 Hackensack Avenue, Suite 200
Paramus Office
140 East Ridgewood Avenue
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text:
11th Swedish Bioinformatics Workshop
for PhD students and Postdocs
29–30 September 2011.
Dept. of Astronomy and Theoretical Physics and Dept. of Biology, Lund University
[Registration closed]
Submitted abstracts:
Accepted abstracts for oral presentations
Richard Bonneau
Learning hematopoetic differentiation networks in human and mouse integrated data-sets with focus on Th17 differentiation and function
The talk will focus specifically on an integrated analysis of ChIP-seq of key epigenetic marks and immune-relevant transcription factors, RNA-seq time series following T-cell differentiation, and microarray data spanning several white blood cell lineages. Much of this data has been collected as part of a large consortia investigating diverse aspects of the human and mouse immune systems (NYU, Penn, the Broad/ImmGen, Hudson Alpha, and others). We discuss practical considerations for matching experimental designs to our inference pipeline. Our methods allows us to integrate human and mouse data-sets to both improve the accuracy of our estimation of conserved regulatory modules and highlight species specific regulatory modules. New developments include: 1) a multiple-species (or comparative) version of the cMonkey biclustering algorithms (used to find conserved and species specific modules in an integrated mouse-human data-set) and 2) a new inference pipeline that explicitly integrates epigenetic marks, chip-seq, genetic perturbations, microarray and RNA-seq data.
Erica Manesso
Department of Astronomy and Theoretical Physics
Lund University
Dynamics inside the hematopoietic hierarchy in adult mice
Bone marrow hematopoietic stem cells are responsible for both daily preservation of all blood cell types and for repair after hematopoietic injuries. Substantial efforts have been made to identify the hierarchy of progenitors for all blood cell lineages, yet little is known about the dynamics inside the entire hematopoietic tree. To this end, we developed a dynamic model for the hematopoietic hierarchy for the most important and specific lineages of the tree. In normal conditions, compartment sizes, commitment and net division rates were identified in order to meet the daily production of blood cells, that is circa 3X10^8 cells/day. Furthermore, the implementation of ad hoc feed-backs from differentiated cells to progenitors and from progenitors to hematopoietic stem cells allowed the simulation of common injuries, like hemorrhage and irradiation followed by bone marrow transplantation. In detail, the dynamic model was able to reproduce the expected 2 week-recovery time from a 10% blood loss as well as the need of transplanting myeloid progenitors together with hematopoietic stem cells to protect from anemia and thrombocytopenia following irradiation.
This work was supported by the Swedish Foundation for Strategic Research (SSF).
Dirk Repsilber
Genetics and Biometry
Leibniz Institute for Farm Animal Biology
Biosignatures from blood: disentangling patterns and cell types in heterogeneous tissue
Screening for predictive biosignatures using statistical learning in heterogeneous tissues -- with blood as prominent example -- is hampered by confounding of molecular profiles with cell type proportions. Non-negative matrix hybridization approaches have been proposed for in-silico deconfounding. However, sample variation in molecular profiles is not retained in these approaches. Therefore, statistical learning methods are not eligible to apply.
Two different possible ways out of this dilemma are presented, and applied to experimental validation data in blood PBMCs together with FACS count data and profiles from sorted cells.
Christof Winter
Improving outcome prediction for cancer patients by network-based ranking of marker genes
Predicting the clinical outcome of cancer patients based on the expression of marker genes in their tumors has received increasing interest in the past decade. Accurate predictors of outcome and response to therapy could be used to personalize and thereby improve therapy. State of the art methods used so far, however, often found marker genes with limited prediction accuracy, limited reproducibility, and unclear biological relevance. To address this problem, we developed a novel computational approach to identify genes prognostic for outcome that couples gene expression measurements from primary tumor samples with a network of known relationships between the genes. Our approach ranks genes according to their prognostic relevance using both expression and network information in a manner similar to Google's PageRank. We applied this method to gene expression profiles which we obtained from 30 patients with pancreatic cancer, and identified seven candidate marker genes prognostic for outcome. Compared to genes found with state of the art methods such as Pearson correlation of gene expression with survival time, we improve the prediction accuracy by up to 7%. Accuracies were assessed using support vector machine classifiers and Monte Carlo cross-validation. We then validated the prognostic value of our seven candidate markers using immunohistochemistry on an independent set of 412 pancreatic cancer samples. Notably, signatures derived from our candidate markers were independently predictive of outcome and superior to established clinical prognostic factors such as grade, tumor size, and nodal status. The amount of genomic data of individual tumors will grow rapidly in the future. Our algorithm meets the need for powerful computational approaches that will be key to exploit these data for personalized cancer therapies in clinical practice.
Fredrik Boulund
Mathematical Sciences, Division of Mathematical Statistics
A computational pipeline employing hidden markov models for the identification of novel antibiotic resistance genes
Fluoroquinolones are an important family of broad spectrum antibiotics. Bacterial resistance to fluoroquinolones has recently been discovered through a class of mobile resistance genes called qnr. Currently, there are five known classes of plasmid mediated qnr-genes, though this is believed to be only a fraction of the true number of gene variants. The Qnr proteins are pentapeptide repeat proteins that contain a specific repeating pattern of five amino acid residues in their sequence. Using this unique structural feature we created a hidden Markov model (HMM) based on the sequences of all currently known plasmid mediated variants. To enable identification of novel qnr-like genes or classes, we developed a computational pipeline to search large data sets using the model. Performance evaluation of the pipeline accuracy showed that the power for detecting a novel class of genes is more than 99% for input sequences as short as 100 nucleotides. We applied the pipeline to several data sets, both annotated (e.g. NCBI GenBank) and metagenomic sequences produced with high-throughput sequencing technologies (e.g. CAMERA, Meta-Hit). In this project, we searched over 470 million sequences, totaling more than 700 gigabytes of amino acid sequences. The method identified all previously known qnr-genes, both plasmid mediated and chromosomal, as well as several novel candidates from both categories. In addition, we discovered several sequences in the current databases that were misannotated. We also present a refined model incorporating the diversity of the novel qnr-genes for further use in related research.
Anna Johnning
Institute of Neuroscience and Physiology
The genome of an extensively drug-resistant bacterium
Antibiotics save millions of lives every year and are crucial for fighting disease worldwide. However, their extensive usage also promotes antibiotic resistance – one of the most important challenges for the health care sector. As bacteria can move between environments and resistance genes can be transferred horizontally between bacterial species, it is important to protect the environmental bacteria from excessive antibiotic exposure. We have sequenced the genome of the extensively drug- resistant Ochrobactrum intermedium strain CCUG 57381, an environmental bacterium and opportunistic pathogen. The strain was isolated from a sample taken inside a treatment plant in India receiving wastewater from approximately 90 drug manufacturers. The treated effluent contains pharmaceuticals at up to ten times human therapeutic plasma levels, including several broad spectrum fluoroquinolone antibiotics. The bacterium was found to be resistant to 36 of 39 tested antibiotics belonging to several different clinically relevant classes of antibiotics. Massively parallel pyrosequencing (454 sequencing) of its genome resulted in an average sixteen-fold coverage. Comparative genomics were used to analyze the genome of the resistant isolate in relation to the already sequenced reference strain O. intermedium LMG 3301T. The analysis revealed structural differences between the strains, including insertions and large deletions. Several non-synonymous point mutations were detected in protein coding sequences, as well as alterations in the ribosomal RNA genes. The quinolone target enzymes, DNA gyrase and topoisomerase IV, showed 9 amino acid changes in the isolate, three of which are known to cause quinolone resistance in Escherichia coli. There was also a considerable amount of sequence reads that did not map onto the reference genome, suggesting that the isolate has acquired large regions (total of 1 Mb) of novel genetic material, e.g. plasmids. With these reads, we assembled a number of regions associated with multiresistance containing arrays of resistance genes. The results presented here demonstrate the power of second generation sequencing technology as well as the need for sustainable management of antibiotic waste.
Daniel Larsson
Cell and Molecular Biology
Initial Stages of Viral Capsid Dissolution Studied by Molecular Simulations
The low calcium concentration of plant cells is exploited by viruses which use it as the trigger to open up and release the genetic material following viral entry. The nucleic acid can subsequently recruit the replication machinery of the host in order to multiply. In microsecond trajectories of the protein capsid of the Satellite Tobacco Necrosis Virus without the 92 structural calcium ions we observed a significantly increased radial expansion compared to simulations of the capsid with Ca2+. There was a substantial increase in the net flow of water into the capsid upon removal of the ions, passing pre- dominantly between the proteins at the 3-fold symmetry axis. The simulations provide insights into how a virus can dissolve its capsid structure in full atomic detail.
Peter Swain
Modelling and measuring stochastic gene expression
Iskra Staneva
Astronomy and Theoretical Physics
It works in theory: the binding of peptides to PDZ domains
PDZ domains are found in proteins that are involved in signaling processes. They enable interactions by binding to linear sequence motifs at the C-termini of other proteins. The PDZ domains can be divided into different groups, depending on what kind of motifs they recognize. A question that naturally follows is whether there are any differences in the peptide binding process itself. We address this by performing all-atom Monte Carlo simulations of representatives from the two major groups. The atoms are subject to an effective force field, mainly modeling hydrogen bonds together with hydrophobic and electrostatic interactions. This enables an extensive sampling of the PDZ domain-peptide conformational space and renders minimum-energy structures very similar to the experimentally determined complexes. Analysis of free-energy landscapes and the temperature dependence of various observables suggests that the binding dynamics, which overall can be described by a two-state model, indeed might be different for the two groups.
Sebastian Rämisch
Biochemistry & Structural Biology
Computational Design of Self-assembling Leucine-rich Repeat Proteins
Leucine-rich repeat containing proteins (LRRs) are ubiquitous protein binders and include many receptor proteins of the innate immune system. Individual repeating units of the human ribonuclease inhibitor were analysed for their ability to form closed ring structures of multiple symmetries by employing the ROSETTA symmetrical docking protocol. One repeating unit was chosen for design of a novel highly symmetrical LRR-protein by iterative cycles of symmetrical docking with C10-symmetry and symmetrical design. Two designed protein, comprising half a ring, were successfully expressed, purified, and analysed for self-assembling, surprisingly revealing stable monomeric proteins. Smaller units will be tested, to reveal the smallest possible assembling module, and hence gain insight into the possible evolutionary origin of repeat proteins in general.
Yasser Gaber
Molecular Modeling as a Rational Design Tool of an Esterase
Rational design of enzymes is an approach to modify enzyme properties based on mechanistic and structural knowledge of the enzyme. It has been greatly enhanced by the availability of molecular simulation software. We have used YASARA molecular modelling software to design mutants of an esterase (PLE) in order to enhance its enzyme activity and enantioselectivity toward a racemic compound (clopidogrel). Molecular modelling of the R and S enantiomers inside the active site of PLE model was performed to understand the possible geometric hindrances for formation of the enzyme-substrate tetrahedral intermediate. Glu203 in the vicinity of the active site was found to form hydrogen bonds with the catalytic His449 and GGG(X) motif residues. The hydrogen bonding of these residues should be available for the stabilization of the tetrahedral intermediate (Fig.1). Hence, Glu203 would be a potential site for a site directed mutation in the PLE gene expressed in Escherichia coli.
Olena Ishchuk Biology
Parallel evoultion in yeast
Saccharomyces yeasts degrade sugars to two-carbon components, in particular ethanol, even in the presence of excess oxygen. This characteristic is called the Crabtree effect and is the background for the 'make-accumulate-consume' life strategy, which in natural habitats helps Saccharomyces yeasts to out-compete other microorganisms. A global promoter rewiring in the Saccharomyces cerevisiae lineage, which occurred around 100 mya, was one of the main molecular events providing the background for evolution of this strategy. Here we show that the Dekkera bruxellensis lineage, which separated from the Saccharomyces yeasts more than 200 mya, also efficiently makes, accumulates and consumes ethanol and acetic acid. Analysis of promoter sequences indicates that both lineages independently underwent a massive loss of a specific cis-regulatory element from dozens of genes associated with respiration, and we show that also in D. bruxellensis this promoter rewiring contributes to the observed Crabtree effect.
Rozpedowska et al. (2011) Nat Commun.2:302.
Henk-Jan Joosten
Bio-Prodict
3DM protein engineering superfamily databases
A powerful method to gain biological insights in the functioning of a protein is to use data available for the protein (super)-family. The large amounts of different data types can be used to detect correlations that reveal the function of amino acids, but collecting and analyzing the data is difficult and time consuming. Therefore, protein super-family specific databases are needed.
3DM was developed to automatically build such protein super-family databases. 3DM systems are based on a automatically generated structure based super-family alignment and many different data types, such as mutational information (extracted from literature, mutation databases, Swiss-Prot, OMIM, PDB files, etc), ligand- and substrate contacts, protein-protein interactions, SNP data, and data derived form the alignment (e.g. correlated mutations, amino acid conservation, and amino acid distribution) are all connected to each other, to the alignment, and to the protein structures. This connectivity enables detection of hidden correlations, transfer of different data types between family members, and easy visualization of data in the alignment and in all super-family structures.
3DM was used to change/improve many different enzyme characteristics such as activity, specificity, enantio-selectivity, thermostability, etc. It was shown that 3DM can be used to predict deleterious mutations and this knowledge was used to design "smart libraries" that contain a small number of mutations with a high number of successful constructs. 3DM was used to predict specific double mutants that increased enzyme activity of which both single mutations decreased the activity of the enzyme. 3DM was used to design a strong inhibitor for an enzyme and 3DM was used to understand the difference between inhibiting and activating compounds.


Although dystonia* has no cure, there are a number of treatments available for finding relief. DBS may be an option for you if you have chronic, intractable (drug refractory) primary dystonia, including generalized and/or segmental dystonia, hemidystonia, and cervical dystonia (torticollis), have not had success managing your symptoms with medication and are 7 years of age or above.
DBS may be an option for you if you have chronic, intractable (drug refractory) primary dystonia, including generalized and/or segmental dystonia, hemidystonia, and cervical dystonia (torticollis), have not had success managing your symptoms with medication and are 7 years of age or above.
DBS Therapy may help control some symptoms of dystonia, including involuntary movements, but, it is not a cure. Your symptoms will return when the system is turned off. The treatment of dystonia is approved under a Humanitarian Device Exemption. The effectiveness of this device for this use has not been demonstrated.
dystonia-foundation.org. Accessed February 28, 2017.


I got to Tulsa way after dark last night… Hey Tulsa, turn on the damn street light. It was dark and rainy, and the hotel was hidden two blocks off the street.
This morning I woke up to a sunny day and looked around Tulsa.
Your donation will be processed by Terlingua Cares, which operates under the Umbrella of the Big Bend Citizen's Alliance which is a 501.c.3 non profit organization.
Terlingua Cares will then turn the money over to Marcos Paredes, who will work with Catfish to acquire transportation.
International blues-rock singer, Elizabeth Lee, visited Terlingua for a couple of special acoustic shows. She's a festival/concert performer with her band in Europe, and currently has a song on the Euro-pop charts.
Sunday night, she was joined by Trevor Hickle and myself at the High Sierra Bar and Grill. Monday, she and I played at the Starlight Theatre.
Hormones were carbonated, and Terlinguists were treated to some world-class blues rock.
We're taking Terlingua Music to the world!
If you're in the Big Bend, you can get your copy of Terlingua Music– the photo-book at the Trading Post near the Starlight Theatre or the General Store in Lajitas.
If you're in some strange and exotic location, for example, North of Alpine, Texas, you can grab your copy now at Amazon.com.
Austin's (and soon to be Terlingua's) own Bruce Salmon brought his Brewski Salmineo show to the Starlight Theatre last night. He was joined by Chase Peeler on Saxophone.


text:
In the writers studio
On Writing: Cynthia Bond
Ahead of tomorrow's 2016 winner announcement, we caught up with shortlisted author Cynthia Bond to discuss the inspiration behind her debut novel Ruby.
I've often said that writing Ruby was like making a pot of New Orleans Gumbo, a spicy thick stew chock full of shrimp, Andoiuille Sausage, chicken, catfish, crab, peppers—really, whatever can be imagined, all you have known can be stirred into the pot. It takes easily 6-8 hours to get it right. My ex-husband, who is from Yorkshire, often compared it to a lamb hot pot. The ten years of writing the Ruby trilogy was like that. The following are the more distinct ingredients:
My mother's scars. She would roll up her left sleeve and my sister and I would lean close to inspect the smooth island of blanched white where a teacup had been hurled and broken into her elbow. The tiny dot on the sole of her foot when at seven she had stepped on a rusty nail and had worn a slab of salt pork wrapped around it all summer, leaving oiled stains on the floorboards. Growing up in her all-black Liberty Community in East Texas my mother had never been to a doctor, nor had anyone she knew. Instead they went to a Natural Healer, a women who dispensed herbs, roots, powders to mend ailments. If this did not work, then, my mother said, people just died.
This was the way of life in the 1940's. Although my sister and I had been born in Texas, where our father taught speech and literature at Prairieview University, we had moved and quickly become city girls growing up on the Kansas University campus. It was the late sixties and the campus was filled with picket signs and protests and buildings being burned, yet we marveled at the illustration of our mother's body. We knew nothing of farms and growing cotton, and a father (our granddaddy) who found water with a divining rod. While my mother became a Community College President, and is still the most beautiful woman any of us had ever seen—her scars were our favorite chapter book, which we begged to hear again and again. These stories were the inspiration for Liberty Township in my novel.
My grandmother's voice and the tight, rhythmic shaking of her head when she told what had happened to our Aunt Carrie. My professorial father had a tape recorder and leaned over her like a journalist. My sister and I had heard whispers of the story before, but never like this. We learned it was a mournful song threaded through a needle that stitched our family quilt. She told how my Aunt was involved with a married white man in the late 1930's. How the town had risen up when he built her a house in the woods, and crashed down when the Sheriff and his Deputies stole away with her and her two sisters one night. They placed her sisters in the jail and dragged my Aunt to a hill and shot her so many times no one could recognize her, then stuffed her body into a burlap sack and threw it on her daddy's porch. Aunt Carrie, and the justice never afforded her, my mother, nor any subsequent generation—My ability to break this silence was also an inspiration for Ruby
The New York section of Ruby was inspired by the Black Literati we met in Lawrence, Kansas when we were children. As one of the few black instructors at K.U. my father, and our home a dock for the great, grand literary ships of our time, Gwendolyn Brooks, Sonya Sanchez, Maya Angelou, our cousin Julian Bond and many others who sat in our living room, laughed like music, conspired and unfolded tales like candy wrappers. The stories dark and sweet. When I was an adult, studying writing with the brilliant John Rechy, author of the seminal novel City of Night I learned and read about Gay life and prostitution in New York in the 1950's. Both fed and created Ruby's story in New York.
The secrets of my own life seasoned this story. Bitter herbs, and taro root and blood falling onto concrete. The stories of the homeless youth I taught in Los Angeles. The recovery houses, the shelters, the community buildings and sitting on the sidewalks. Stories that resonated with my own, stories that did not, but that I knew because, like so many women, I had walked through my own fire, then once safe, ignited flames within myself, trying to burn, to immolate, so that I knew the young heroin addict who had almost died in the Denny's bathroom, I knew the young women lost in a cult, I knew the anger of the transgendered young woman who had been beaten by police. I had not walked it, but I knew it, and they could see that I did.
These stories mingled and lead me to the millions of children locked in small rooms, waiting for grown men to enter. The girls naked, terrified, who are raped by 10, 15, 20 men a day until all that they are–their likes, dislikes, favorite sweets and games and how they loved the wind fluffing their hair, or the scent of honeysuckle, or jasmine and mud cakes and scary closets–all of that gathers into a cloud, leaves their bodies and hides in the corner for safety, in order to preserve, protect and one day retrieve. But after days after months after years, if these children manage to stay alive, they watch helplessly as the cloud rises from the corner and slips out of the window. So that they become only what the men tell them they are. I wrote Ruby for all of those girls who have forgotten. I wrote Ruby, as impossible as it may sound, to try to hold the souls of all of those children, until they can come back to reclaim them
Finally I was inspired by how story can weave together into a tight rope that binds and heals. I learned that through telling the best story, crafting the best form of structure I could remember, the heavy full laughter and gossipy jokes, and playing the dozens the memory of which, can carry us through the deepest pain. How the scent of night blooming jasmine or a gardenia, or blackberry cobbler or fried catfish, the deepest kiss, the sweat and magnet of passion—love, sweet like powered sugar at the back of your throat, all remembered, all carried like a knapsack. How these were the greatest inspirations of all, for they allowed me to survive my story, and ultimately grow and change myself.
To find out more about Ruby and see the 2016 shortlist in full click here. Don't forget to tell us what you think of the books on Twitter, Facebook and Instagram.
Shortlist readings round up
Inspiring reads at the Grazia Book Club


These layouts are inspired by the designs at Elegant Themes – we are making them available to the community for a choose your price as it took a good deal of work to get them together. So, if you do not want to pay – no problem just add a Zero to the price box and enjoy.
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text:
Home/Sociology/Society and Culture in India: A Reader
Categories: Culture Studies, Education, Public Policy, Sociology
Society and Culture in India: A Reader
by:	Subas Mohapatra
Society and Culture in India is a collection of eighteen carefully chosen essays written by internationally famous sociologists whose work is on India. It has been designed to take the reader through the discipline of Sociology to get an understanding of the complex nature of Indian society. The editor of the volume, Subas Mohapatra has […]
Books of Subas Mohapatra
Society and Culture in India: A Reader 2017
Society and Culture in India is a collection of eighteen carefully chosen essays written by internationally famous sociologists whose work is on India. It has been designed to take the reader through the discipline of Sociology to get an understanding of the complex nature of Indian society.
The editor of the volume, Subas Mohapatra has very perceptively grouped the various readings in the book under five main heads, they are: 'An Introduction to Sociology and Pioneering Sociologists', 'Sociology of Caste Past and Present', 'Rural and Agrarian Society', 'Poverty and Development' and 'Contemporary Social Issues'.
The essays in this book dwell on several separate subject areas of sociology. This enables the Reader to provide a comprehensive view of the discipline of sociology itself as well as the society it tries to understand.
Some of the main concerns of this book are: growth and development of sociology in India; changing nature of caste, village and rural society; sociological analysis of poverty and contemporary issues associated with civil society; gender inequality and secularism and communalism.
The Reader does not try to be thematically exhaustive but it nevertheless enables one to see order beneath the everyday confusions of life in India.
Subas Mohapatra
Subas Mohapatra is an Associate Professor of Sociology at Sri Venkateswara College, University of Delhi. He has been engaged in teaching and research since 1984. His areas of specialization include Social Stratification, Sociology of Kinship, Indian Society and Sociology of Education. He has delivered lectures and participated in discussions and seminars in different institutions of repute. He regularly participates in television talks and delivers lectures in Doordarshan Vyas-television programmes of UGC.
"Society and Culture in India: A Reader" Cancel reply
Religion and Personal Law in Secular India: A Call to Judgement by: Gerald James Larson
This book provides a comprehensive look into the issues and challenges that India faces as it tries to put a uniform civil code into practice. Scholars representing a wide range of disciplines, from both North America and India, provide perspective on complex issues of multiculturalism that characterizes Indian society and identities. Readers seeking a deeper understanding of Indian history and culture will find a sensitive handling of the tensions between religious law and the claims of a modern, secular state in this timely volume.
The Sundarbans: Folk Deities, Monsters and Mortals by: Sutapa Chatterjee Sarkar
The lower deltaic Bengal, the Sundarbans has always had a life of its own, unique in its distinctive natural aspect and social development. Geographical and ecological evidence indicates that most of the area used to be once covered with dense, impenetrable jungle even as patches of cultivation sprang intermittently into life and then disappeared. A continuous struggle ensued between man and nature, as portrayed in the punthi literature that thrived in lower deltaic Bengal between the seventeenth and nineteenth centuries.
The construction of a permanent railroad connecting Calcutta to Canning further facilitated the influx of new ideas and these, subsequently, found expression in the spreading of co-operative movements, formation of peasant organizations, and finally culminated in open rebellion by the peasants (Tebhaga Movement). The struggle between men and the dangerous forests was therefore overshadowed by the conflict among men.
This book will be of great interest to students of history, sociology, anthropology and economic geography.
Sikkim Human Development Report by:
Very little is known about Sikkim. This book outlines its development since it became a part of the Indian Union in 1975. It covers subjects such as population, poverty and planning; health, education and the status of women; land and agriculture; forest and environment; infrastructure for development such as industry, power and state finance; and governance for sustainable human development.
Tamil Brahmans: The Making of a Middle-Class Caste by:
A cruise along the streets of Chennai – or Silicon Valley – filled with professional young Indian men and women, reveals the new face of India. In the twenty-first century, Indians have acquired a new kind of global visibility, one of rapid economic advancement and, in the information technology industry, spectacular prowess.
In this book C.J.Fuller and Haripriya Narasimhan examine one particularly striking group who have taken part in this development: Tamil Brahmans – a formerly traditional, rural, high-caste elite who have transformed themselves into a new middle-class caste in India, the United States, and elsewhere.
Viramma: Life of a Dalit by: Viramma, Jean-Luc Racine, Josiane Racine,
This is the first Indian edition of this remarkable book which created a great impact in France and was subsequently translated into English and Italian. This edition carries a fresh Afterword by Jean-Luc and Josiane Racine.
Viramma, an untouchable woman by birth, and listed as one of the authors, narrated the story of her life over a period of ten years to Josiane Racine, a Tamil-born ethnomusicologist educated in France. This book is the result of that conversation.
Copyright © Social Science Press, All rights reserved. Social Science Press logo designed by Arpan Mukhopadhyay.


text:
Q: undefined method `valid_xml?' I am new to ruby. I keep getting undefined method 'valid_xml'? What am I doing wrong?
require 'rexml/document'
include REXML
begin
    good_xml = %{
     <groceries>

      <bread>Wheat</bread>
      <bread>Quadrotriticale</bread>
     </groceries>}
puts(good_xml)
valid_xml?(good_xml)
puts("good read")
rescue Exception => e
puts(e.message)
end

and here is the output
-bash-4.1$ ruby test.rb

     <groceries>

      <bread>Wheat</bread>
      <bread>Quadrotriticale</bread>
     </groceries>
undefined method `valid_xml?' for main:Object

Here is the ruby version I have
ruby 1.8.7 (2009-12-24 patchlevel 248) [x86_64-linux]

A: valid_xml? is not defined in REXML (and neither did you define it). You could define it like this:
def valid_xml?(xml)
   REXML::Document.new(xml)
   true
rescue REXML::ParseException
   false
end

redpajama_set_name: RedPajamaStackExchange


text:
Blood Orange soars in a variety of modes
Musician Dev Hynes explains how 'Negro Swan' became his most pointed record yet.
Zack Ruskin September 7, 2018Updated: September 20, 2018, 11:11 pm
Dev Hynes, a.k.a. Blood Orange. Photo: Nick Hardwood
To draw an accurate portrait of Devonté Hynes, you'll need every color in the box. His talents as a singer, producer, director, guitarist, songwriter and dancer tell some of the story, but Hynes has never subscribed to the idea that art must come with answers.
Hailing from London, Hynes started with a United Kingdom dance-pop band cheekily named Test Icicles. After moving to New York in 2007, he teamed with acclaimed producer Mike Mogis in Omaha, Neb., to create the first of two albums under the moniker Lightspeed Champion. On Thursday, Sept. 20, he's scheduled to perform at Oakland's Fox Theater as Blood Orange, the project he's been recording and performing as since 2011.
While the 32-year-old is quick to credit luck as the force that has guided his career, there's a reason artists ranging from Philip Glass to Carly Rae Jepsen continue to seek him out as a collaborator. For one, he's an immensely gifted musician, capable of playing classical piano at Carnegie Hall one night and covering Blink-182 songs alongside Florence Welch the next. He's also the rare artist who has no interest in letting his ego be his guide.
"If you were to look back at my last three albums," Hynes says, "I've slowly been shrinking my literal voice."
On his latest record, "Negro Swan," Hynes pushes this experiment even further, utilizing transgender activist and writer Janet Mock as a narrator of sorts on an album that traverses soundscapes of funk, chillwave and R&B in an effort to explore the complex — and often harrowing — experience of what it means to be marginalized in the world today.
In "Dagenham Dream," Hynes recalls the brutality of schoolyard bullies who would beat him for being a young black boy who wore makeup and painted his nails. "Orlando," a lush chaos of piano and guitar underscored with the sounds of a city street, is another repudiation of machismo made all the more striking when conveyed in Hynes' gleaming falsetto. "Charcoal Baby" harks back to racial slurs of yore as Hynes relays his weariness over ancient struggles that are still all too contemporary.
Hynes is hesitant to label "Negro Swan" his most autobiographical album, but he will concede that there is something noticeably more naked about his latest collection of songs.
"It's probably the one that's the most stripped of metaphor," he says. "It's as autobiographical as everything else, but I think the writing and production and musicality is a little bit more direct now. I don't want to use the word 'sharper,' but it's a little bit more pointed."
Technically, Blood Orange is a one-man enterprise, but part of what has made the project unique is the sheer variety of guest contributors who always seem to organically manifest on his songs at just the right time. On "Negro Swan," Hynes features hip-hop heavyweights like A$AP Rocky and Puff Daddy as well as gospel singing from Ian Isiah and vocals from the Internet's Steve Lacy.
There's even one artist who doesn't appear on "Negro Swan" yet still managed to influence the record: Solange. The two have a history that goes back to the 2012 EP "True" — an album largely credited as the younger Knowles' breakthrough — and it was Solange who convinced Hynes not to cut the track "Minetta Creek" from his latest album.
Hynes is a big believer in happenstance. To that end, the music of "Negro Swan" was in part the result of his booking time at studios and using only whatever was available on site when he got there. At a space in Los Angeles, Hynes saw that there was an acoustic guitar, which led to the creation of two of the album's tracks.
"For some time, I've wanted to try to implement acoustic guitar into whatever Blood Orange is," he says. "Literally the three days I booked at that studio is how 'Runnin' ' and 'Smoke' came to be, essentially. I feel like I finally worked it out."
Thus, in a sense, the music of Blood Orange is never truly finished until it reaches listeners' ears. At any moment in the process, the opinion of a respected peer might lead to a drastic change — uncertain possibilities that fuel Hynes and drive his creativity.
"It ties into my whole thing where I don't necessarily believe I'm the best person for the job," Hynes explains. "I can start things, but I'm maybe not the best at them. I think that's why I collaborate. I like that band mentality, but I can't be in one."
Blood Orange: 8 p.m. Thursday, Sept. 20. $35-$45. The Fox Theater, 1807 Telegraph Ave., Oakland. thefoxoakland.com
Zack Ruskin
Zack Ruskin Zack Ruskin is a Bay Area freelance writer


This Valentine's Day we're focusing on the tradition of making homemade cards. It seems like such a small activity but there's something extra special about using this time together to teach your child how to express their love and gratitude for the people in their lives.
Colored pencils, crayons, markers, or whatever your kiddo likes to draw with!
Start by cutting out different hearts in different colors and sizes. These can be used to either decorate the front of the card or be strung together to create a pop-up on the inside of the card. Ask your little one where they want the hearts to go and let the creativity flow!
Once you have your cards decorated, it's time help your little one personalize their Valentines! A simple and easy way to do this is by adding your Valentine's initials on the front of the card. Next, help your little one write a sweet note on the inside. This is a great opportunity to encourage them to think of something nice to say about each recipient. That's what Valentine's Day is really all about!
Show us how you'll be spreading the love and tag your Valentine's Day cards using #lovemypbk. Happy Valentine's Day!