The Matteson Historical Society was founded in 1975 to collect items of significance to Matteson's storied past. The Society now houses it's vast collection in the Matteson Historical Museum for all to enjoy. The mission of the museum is to curate, conserve and provide access to the Society's historical documents and artifacts. From educational programs to a fascinating tourist destination, the museum offers an impressive look at Matteson's past.
Newspaper clippings: From 1943 to the present.
Photographs: People, places and things from the 19th, 20th and 21st centuries; aerial views.
Documents: Documents are listed in a 100 page catalog and include - Village government archives; Matteson Volunteer Fire Department minutes books and photo album; Matteson Civic Association; School District 162; histories of Matteson; property data; church archives; township and village publications; railroad history pertaining to the area; Lincoln Highway history; rare books used by early settlers, with particular emphasis on religious materials printed in German; early German encyclopedias and periodicals. Copy of Archives Catalogue is available at the Matteson Public Library.
Matteson Volunteer Fire Department: 1894 pumper and hose cart, helmets and uniforms.
Clothing: Early twentieth century women's clothing; military uniforms; firefighter uniforms.
Education: Classroom teachers and homeschoolers are invited to see how museum exhibits can be used as teaching aids. The museum also provides customized educational programs for school groups.
Genealogist: Consult obituary files, family histories and oral histories, and be linked to south suburban genealogical sources.
Researchers: (students, historians, writers, real estate developers, environmental engineers and others) Find information on railroads, farms, local businesses, properties, food history, Butterfield Creek, Lincoln Highway, Midwest architecture, German settlements in the Midwest region.
Speakers/Programs: Presentations on Matteson history and the Matteson Historical Museum.
Summer Passport Program: Fun for children ages 4 through 12 throughout the suburbs from June through August. Call the MHM for more details.
Farm Implements: A scythe, and egg crate, a corrnshucker and a milk can...early Matteson was a farming community like thousands of others across the U.S. around 1900.
Dettmering's Tavern: One of the earliest businesses in Matteson, Dettmering's served as a farmers' hotel and a lunchroom for the locals. See the original mirror and bar from Dettmering's Tavern at MHM.
Illinois Central Railroad: Remember those wicker seats that snagged nylons during commutes to Chicago? MHM has two of them.
Household Appliances and Clothing: Outdoor washing tubs and a 1930's wringer washer are on display, and ladies dresses with waists so tiny you won't believe they're real.
Matteson Businesses: Typewriters and a calculator that stands on it's own legs and wheels are just two of the many pieces of business equipment and promotional items on exhibit at MHM.


text:
#include "archive_platform.h"
__FBSDID("$FreeBSD: head/lib/libarchive/archive_write_set_format_cpio.c 201170 2009-12-29 06:34:23Z kientzle $");

#ifdef HAVE_ERRNO_H
#include <errno.h>
#endif
#include <stdio.h>
#ifdef HAVE_STDLIB_H
#include <stdlib.h>
#endif
#ifdef HAVE_STRING_H
#include <string.h>
#endif

#include "archive.h"
#include "archive_entry.h"
#include "archive_private.h"
#include "archive_write_private.h"

static ssize_t	archive_write_cpio_data(struct archive_write *,
		    const void *buff, size_t s);
static int	archive_write_cpio_finish(struct archive_write *);
static int	archive_write_cpio_destroy(struct archive_write *);
static int	archive_write_cpio_finish_entry(struct archive_write *);
static int	archive_write_cpio_header(struct archive_write *,
		    struct archive_entry *);
static int	format_octal(int64_t, void *, int);
static int64_t	format_octal_recursive(int64_t, char *, int);

struct cpio {
	uint64_t	  entry_bytes_remaining;

	int64_t		  ino_next;

	struct		 { int64_t old; int new;} *ino_list;
	size_t		  ino_list_size;
	size_t		  ino_list_next;
};

struct cpio_header {
	char	c_magic[6];
	char	c_dev[6];
	char	c_ino[6];
	char	c_mode[6];
	char	c_uid[6];
	char	c_gid[6];
	char	c_nlink[6];
	char	c_rdev[6];
	char	c_mtime[11];
	char	c_namesize[6];
	char	c_filesize[11];
};

/*
 * Set output format to 'cpio' format.
 */
int
archive_write_set_format_cpio(struct archive *_a)
{
	struct archive_write *a = (struct archive_write *)_a;
	struct cpio *cpio;

	/* If someone else was already registered, unregister them. */
	if (a->format_destroy != NULL)
		(a->format_destroy)(a);

	cpio = (struct cpio *)malloc(sizeof(*cpio));
	if (cpio == NULL) {
		archive_set_error(&a->archive, ENOMEM, "Can't allocate cpio data");
		return (ARCHIVE_FATAL);
	}
	memset(cpio, 0, sizeof(*cpio));
	a->format_data = cpio;

	a->pad_uncompressed = 1;
	a->format_name = "cpio";
	a->format_write_header = archive_write_cpio_header;
	a->format_write_data = archive_write_cpio_data;
	a->format_finish_entry = archive_write_cpio_finish_entry;
	a->format_finish = archive_write_cpio_finish;
	a->format_destroy = archive_write_cpio_destroy;
	a->archive.archive_format = ARCHIVE_FORMAT_CPIO_POSIX;
	a->archive.archive_format_name = "POSIX cpio";
	return (ARCHIVE_OK);
}

/*
 * Ino values are as long as 64 bits on some systems; cpio format
 * only allows 18 bits and relies on the ino values to identify hardlinked
 * files.  So, we can't merely "hash" the ino numbers since collisions
 * would corrupt the archive.  Instead, we generate synthetic ino values
 * to store in the archive and maintain a map of original ino values to
 * synthetic ones so we can preserve hardlink information.
 *
 * TODO: Make this more efficient.  It's not as bad as it looks (most
 * files don't have any hardlinks and we don't do any work here for those),
 * but it wouldn't be hard to do better.
 *
 * TODO: Work with dev/ino pairs here instead of just ino values.
 */
static int
synthesize_ino_value(struct cpio *cpio, struct archive_entry *entry)
{
	int64_t ino = archive_entry_ino64(entry);
	int ino_new;
	size_t i;

	/*
	 * If no index number was given, don't assign one.  In
	 * particular, this handles the end-of-archive marker
	 * correctly by giving it a zero index value.  (This is also
	 * why we start our synthetic index numbers with one below.)
	 */
	if (ino == 0)
		return (0);

	/* Don't store a mapping if we don't need to. */
	if (archive_entry_nlink(entry) < 2) {
		return ++cpio->ino_next;
	}

	/* Look up old ino; if we have it, this is a hardlink
	 * and we reuse the same value. */
	for (i = 0; i < cpio->ino_list_next; ++i) {
		if (cpio->ino_list[i].old == ino)
			return (cpio->ino_list[i].new);
	}

	/* Assign a new index number. */
	ino_new = ++cpio->ino_next;

	/* Ensure space for the new mapping. */
	if (cpio->ino_list_size <= cpio->ino_list_next) {
		size_t newsize = cpio->ino_list_size < 512
		    ? 512 : cpio->ino_list_size * 2;
		void *newlist = realloc(cpio->ino_list,
		    sizeof(cpio->ino_list[0]) * newsize);
		if (newlist == NULL)
			return (-1);

		cpio->ino_list_size = newsize;
		cpio->ino_list = newlist;
	}

	/* Record and return the new value. */
	cpio->ino_list[cpio->ino_list_next].old = ino;
	cpio->ino_list[cpio->ino_list_next].new = ino_new;
	++cpio->ino_list_next;
	return (ino_new);
}

static int
archive_write_cpio_header(struct archive_write *a, struct archive_entry *entry)
{
	struct cpio *cpio;
	const char *p, *path;
	int pathlength, ret, ret2;
	int64_t	ino;
	struct cpio_header	 h;

	cpio = (struct cpio *)a->format_data;
	ret2 = ARCHIVE_OK;

	path = archive_entry_pathname(entry);
	pathlength = (int)strlen(path) + 1; /* Include trailing null. */

	memset(&h, 0, sizeof(h));
	format_octal(070707, &h.c_magic, sizeof(h.c_magic));
	format_octal(archive_entry_dev(entry), &h.c_dev, sizeof(h.c_dev));

	ino = synthesize_ino_value(cpio, entry);
	if (ino < 0) {
		archive_set_error(&a->archive, ENOMEM,
		    "No memory for ino translation table");
		return (ARCHIVE_FATAL);
	} else if (ino > 0777777) {
		archive_set_error(&a->archive, ERANGE,
		    "Too many files for this cpio format");
		return (ARCHIVE_FATAL);
	}
	format_octal(ino & 0777777, &h.c_ino, sizeof(h.c_ino));

	format_octal(archive_entry_mode(entry), &h.c_mode, sizeof(h.c_mode));
	format_octal(archive_entry_uid(entry), &h.c_uid, sizeof(h.c_uid));
	format_octal(archive_entry_gid(entry), &h.c_gid, sizeof(h.c_gid));
	format_octal(archive_entry_nlink(entry), &h.c_nlink, sizeof(h.c_nlink));
	if (archive_entry_filetype(entry) == AE_IFBLK
	    || archive_entry_filetype(entry) == AE_IFCHR)
	    format_octal(archive_entry_dev(entry), &h.c_rdev, sizeof(h.c_rdev));
	else
	    format_octal(0, &h.c_rdev, sizeof(h.c_rdev));
	format_octal(archive_entry_mtime(entry), &h.c_mtime, sizeof(h.c_mtime));
	format_octal(pathlength, &h.c_namesize, sizeof(h.c_namesize));

	/* Non-regular files don't store bodies. */
	if (archive_entry_filetype(entry) != AE_IFREG)
		archive_entry_set_size(entry, 0);

	/* Symlinks get the link written as the body of the entry. */
	p = archive_entry_symlink(entry);
	if (p != NULL  &&  *p != '\0')
		format_octal(strlen(p), &h.c_filesize, sizeof(h.c_filesize));
	else
		format_octal(archive_entry_size(entry),
		    &h.c_filesize, sizeof(h.c_filesize));

	ret = (a->compressor.write)(a, &h, sizeof(h));
	if (ret != ARCHIVE_OK)
		return (ARCHIVE_FATAL);

	ret = (a->compressor.write)(a, path, pathlength);
	if (ret != ARCHIVE_OK)
		return (ARCHIVE_FATAL);

	cpio->entry_bytes_remaining = archive_entry_size(entry);

	/* Write the symlink now. */
	if (p != NULL  &&  *p != '\0')
		ret = (a->compressor.write)(a, p, strlen(p));

	if (ret == ARCHIVE_OK)
		ret = ret2;
	return (ret);
}

static ssize_t
archive_write_cpio_data(struct archive_write *a, const void *buff, size_t s)
{
	struct cpio *cpio;
	int ret;

	cpio = (struct cpio *)a->format_data;
	if (s > cpio->entry_bytes_remaining)
		s = cpio->entry_bytes_remaining;

	ret = (a->compressor.write)(a, buff, s);
	cpio->entry_bytes_remaining -= s;
	if (ret >= 0)
		return (s);
	else
		return (ret);
}

/*
 * Format a number into the specified field.
 */
static int
format_octal(int64_t v, void *p, int digits)
{
	int64_t	max;
	int	ret;

	max = (((int64_t)1) << (digits * 3)) - 1;
	if (v >= 0  &&  v <= max) {
	    format_octal_recursive(v, (char *)p, digits);
	    ret = 0;
	} else {
	    format_octal_recursive(max, (char *)p, digits);
	    ret = -1;
	}
	return (ret);
}

static int64_t
format_octal_recursive(int64_t v, char *p, int s)
{
	if (s == 0)
		return (v);
	v = format_octal_recursive(v, p+1, s-1);
	*p = '0' + (v & 7);
	return (v >> 3);
}

static int
archive_write_cpio_finish(struct archive_write *a)
{
	int er;
	struct archive_entry *trailer;

	trailer = archive_entry_new();
	/* nlink = 1 here for GNU cpio compat. */
	archive_entry_set_nlink(trailer, 1);
	archive_entry_set_pathname(trailer, "TRAILER!!!");
	er = archive_write_cpio_header(a, trailer);
	archive_entry_free(trailer);
	return (er);
}

static int
archive_write_cpio_destroy(struct archive_write *a)
{
	struct cpio *cpio;

	cpio = (struct cpio *)a->format_data;
	free(cpio->ino_list);
	free(cpio);
	a->format_data = NULL;
	return (ARCHIVE_OK);
}

static int
archive_write_cpio_finish_entry(struct archive_write *a)
{
	struct cpio *cpio;
	size_t to_write;
	int ret;

	cpio = (struct cpio *)a->format_data;
	ret = ARCHIVE_OK;
	while (cpio->entry_bytes_remaining > 0) {
		to_write = cpio->entry_bytes_remaining < a->null_length ?
		    cpio->entry_bytes_remaining : a->null_length;
		ret = (a->compressor.write)(a, a->nulls, to_write);
		if (ret != ARCHIVE_OK)
			return (ret);
		cpio->entry_bytes_remaining -= to_write;
	}
	return (ret);
}

redpajama_set_name: RedPajamaGithub


Maybe you have a plan that I'm not aware of, but why not just use a flash drive? If you're funneling a SSD over USB anyways, there's no speed benefit. In fact, it's probably slower.
I've had the same SD card corruption issues that you've had and did this same (similar) method of booting from SD and running from a USB stick and it works wonders.
Actually, I don't have much of a plan, but I tried the USB dongle idea and it failed horribly. I was able to install it and get it to work and was really happy until the USB dongle crapped out and marked itself READ-ONLY. Turns out that this particular thing isn't all that uncommon, so I won't try that again. I really wanted a small SSD, but the price point for this was reasonable, and I've found other possibilities since.


text:
Read Time: 12 mins
Parkinson's Disease Psychosis – Prevalence Patterns Across the EU-5
Published Online: December 5th 2017 European Neurological Review, 2017;12(2):87–91 DOI: https://doi.org/10.17925/ENR.2017.12.02.87
Authors: Keziah Cook, Rathi Suresh, Kai-Jye Lou, J Patrick Kesslak, Doral Fredericks
Parkinson's disease psychosis (PDP) is a clinical condition that affects patients diagnosed with Parkinson's disease (PD) and has a spectrum of neuropsychiatric symptoms distinct from the hallmark motor symptoms. Although prior studies have reported on the prevalence of PDP in select European nations, variations in study design complicate study-to-study comparisons. In this study, we surveyed 1,667 medical practitioners across France, Germany, Italy, Spain, and the UK (collectively, the EU-5) to estimate the prevalence of PDP or symptoms of psychosis among patients with PD. Analysis of the survey data suggest approximately 29% of the general PD population in the EU-5 exhibit signs of PDP. Among the PD population, country-specific rates of PDP are estimated at 30% in France, 27% in Germany, 34% in Italy, 30% in Spain and 21% in the UK. These rates appear in line with those reported in prior country-specific studies. Results from the subset of 437 neurologists who proceeded to take the full survey suggest the symptoms of PDP are disruptive to patients or their respective caregivers in approximately 53% of cases. These results provide a resource that enables cross-country comparison of PDP rates across these major European nations.
Parkinson's disease, psychosis,
prevalence, epidemiology, Europe
Parkinson's disease (PD) is a chronic, progressive, neurological disorder; diagnosis is based on its hallmark motor symptoms which include resting tremor, bradykinesia, rigidity and postural instability.1–3 It is the second most common neurodegenerative disease after Alzheimer's disease, affecting over 1 million individuals across Europe and more than 10 million worldwide.3,4
Parkinson's disease psychosis (PDP) is a distinct non-motor clinical condition that commonly manifests in patients following a primary diagnosis of PD. The condition is characterised by a spectrum of symptoms associated with psychosis such as illusions, false sense of presence, hallucinations and delusions.5 Hallucinations in PD are typically visual, unlike in schizophrenia where hallucinations are often auditory.6 PDP diagnostic criteria developed by the US-based National Institute of Neurological Disorders and Stroke (NINDS)/National Institute of Mental Health (NIMH) work group include having a prior diagnosis of PD and one or more of the aforementioned psychotic symptoms that persist for one month or longer and are not explained by other causes or diagnoses.5 Treatment guidelines from European healthcare authorities generally recommend use of clozapine or quetiapine if withdrawal of add-on medications and dose adjustment for PD medications are insufficient to control the symptoms of psychosis; however, there are safety and efficacy concerns with the use of these drugs.7–9
Understanding the epidemiology of PDP is important, in part, because the chronic, progressive and debilitating condition can magnify the clinical, humanistic and economic burden of PD on patients, communities and healthcare systems. Risk factors for PDP include new medications and changes to existing PD medications, older age, advanced or late-stage PD, dementia, as well as vision and sleep disorders.10 Symptoms of PDP vary in severity and can be disruptive to the patient. Studies in patients with PD have associated symptoms of psychosis with increased odds of reporting suicidal or death ideation11,12 and increased mortality risk.13,14 Multiple studies have also reported positive associations between PDP and dementia, as well as with neuropsychiatric symptoms such as depression and anxiety, suggesting patients with PDP are likely to have high comorbidity burdens.15–17 The symptoms of PDP can also be disruptive to caregivers. Family members are often the party to take on caregiver responsibilities for patients with PDP.18 Multiple studies have found that caregivers of patients with PDP report higher burdens, increased depression and lower quality of life compared with caregivers of PD patients without psychosis.16,19,20 Finally, studies in patients with PD have identified psychosis as one of the most common reasons for hospitalization21,22 and hallucinations as the strongest predictor of placement into nursing homes23,24 suggesting patients with PDP are likely to incur higher healthcare resource utilisation than patients without psychosis.
Though prevalence data on PDP in European nations already exist, estimates vary widely by country and study. Variations in study design, such as data-gathering methods, study inclusion/exclusion criteria, definitions of PDP and symptoms of psychosis complicate study-to-study comparisons, which can make aggregate epidemiological data from a meta-analysis difficult to interpret. A key prospective longitudinal study in Norway has reported the cumulative prevalence of PDP at 60% among 230 patients with PD followed over the 12-year study, with point prevalence rates ranging from 18–49%.25
We surveyed medical practitioners in France, Germany, Italy, Spain and the UK (collectively, the EU-5) to gain a clearer picture of PDP epidemiology and treatment patterns across this region. The current study presents estimates on the prevalence and severity of PDP among patients with PD in the EU-5 based on the survey data. Trends identified within this region could potentially predict trends across the broader EU.
An online survey was developed and targeted to medical practitioner specialists in the EU-5 nations between 21 May 2015 and 24 June 2015 as part of a broader study to address evidence gaps related to PDP epidemiology and treatment patterns among those in the neurologist specialty. The evidence gaps were previously identified from a targeted literature review covering the epidemiology and current treatment paradigm for PDP (unpublished findings).
Measures taken to encourage survey participation included honoraria for respondents who were deemed qualified to take the full survey, and recruitment via email, telephone and fax using large physician databases. All surveys were translated and administered in the local language.
Preliminary qualitative research identified medical practitioners in the neurology specialty who practiced in office and hospital settings as the key providers of treatment to patients with PD. Findings were used to optimise survey targeting and recruitment. The survey was designed with 18 screener questions to help limit the full survey (made up of 65 questions around patient records) to medical practitioners who were most likely to diagnose and provide care for patients with PDP in a manner that is representative of their country of practice. Eligibility to take the full survey was based on participant responses to the screener questions. The screening criteria are presented in Table 1.
The full survey included questions about the percentage of the neurologists' patients with PDP who had disruptive versus non-disruptive symptoms of psychosis, the percentage of patients with disruptive PDP who had severe versus mild-to-moderate PD motor symptomology, and the rates of dementia and cardiovascular disease (CVD) among the patients with disruptive PDP.
Results from both the screener questions and full patient records survey were provided to investigators at Analysis Group in an anonymised aggregated dataset, and were analysed using Microsoft Excel 2010.
BluePrint Research Group, an independent market research firm commissioned by ACADIA Pharmaceuticals Inc., conducted the survey in compliance with data protection legislation and privacy laws, and the codes of conduct of the Market Research Society (MRS) and British Healthcare Business Intelligence Association (BHBIA).
The diagnosis of PDP and symptoms of psychosis were based on the assessment of the medical practitioner. An analysis of responses to two of the screener questions (Q10 and Q11) was used to estimate the prevalence of PDP among the broader PD population. These questions were as follows.
Q10. Of the total patients you have seen/treated in the last 12 months, how many have PD?
Q11. Of the patients you have seen/treated for PD in the last 12 months, how many have PDP, or symptoms of psychosis associated with their PD (which may manifest as a result of PD progression or treatment)?
Q10 and Q11 both included instructions to not multi-count patients who the surveyed medical practitioner has seen multiple times in the last 12 months. To minimise confounding from neuropsychiatric conditions with overlapping symptomology, Q11 also instructed the respondent to exclude patients with PD who have symptoms of psychosis due to other conditions such as schizophrenia, schizo-affective disorder or bipolar disorder.
Respondents who did not answer both screener questions were excluded from the analysis for estimating PDP prevalence. Rates of PDP by country and across the EU-5 were calculated based on the sum of self-reported patient numbers from Q11 divided by the sum of self-reported patient numbers from Q10.
An analysis of neurologist-provided responses to four questions from the full survey (Q1, Q3, Q5 and Q6) was used to estimate the frequency at which PDP symptoms are disruptive to patients and their respective caregivers, as well as the rates of severe and mild-to-moderate PD motor symptomology, dementia and CVD among these patients. Q1 and Q3 also were complemented with a question asking the neurologist to rank the top five features they considered when assessing the disruptiveness of psychosis symptoms and severity of PD motor symptomology (Q2).
Questions 1, 2, 3, 5, and 6 were as follows:
Q1. Of all your patients with PDP, what percentage belong to each of the following categories regarding the disruptiveness of their symptoms of psychosis? (Categories were 'non-disruptive' and 'disruptive').
Q2. Please rank the top 5 features that you consider when determining the severity of PD psychosis symptoms.
Choices for Q2 were as follows:
The degree to which the patient's psychosis interferes with his/her ability to sleep at night.
The degree to which the patient's psychosis interferes with the caregiver's ability to sleep at night.
The degree to which the patient is bothered by his/her symptoms of psychosis (unrelated to sleep).
The degree to which the patient's caregiver is bothered by the patient's symptoms of psychosis (unrelated to sleep).
The frequency of symptoms of psychosis.
The type of symptoms of psychosis the patient is experiencing (i.e., illusions versus visual hallucinations versus delusions).
Whether the patient has insight on his/her psychosis.
The degree to which the patient's psychosis interferes with his/her daily activities.
The degree to which the patient's psychosis negatively impacts his/her quality of life.
The degree to which the patient's psychosis interferes with the caregiver's quality of life.
Other (specify).
Q3. Of all your PDP patients with disruptive symptoms of psychosis, what percentage belong to each of the following categories regarding PD motor symptomatology? (Categories were 'severe' and 'mild-to-moderate').
Q5: Of all your PDP patients with disruptive symptoms of psychosis AND mild-to-moderate PD motor symptomatology, what percentage have the following comorbidities? (Categories were 'dementia', 'CVD' and 'none of these').
Q6: Of all your PDP patients with disruptive symptoms of psychosis AND severe PD motor symptomatology, what percentage have the following comorbidities? (Categories were 'dementia', 'CVD' and 'none of these').
Estimated frequency of symptoms and comorbidities were based on the weighted mean of neurologist-provided estimates to Q1, Q3, Q5 and Q6. Neurologist-provided responses to these questions were weighted according to the estimated prevalence of PDP in each country.
Reported percentages for Q2 are unweighted and based on the frequency at which neurologists ranked each parameter as among the top five they considered when determining the disruptiveness of symptoms of psychosis. The frequency was calculated by dividing the total number of instances where a parameter was ranked as among the top five considered divided by the number of surveyed neurologists.
Survey metrics
A total of 1,667 medical practitioners across the EU-5 participated in the survey. Of these, 1,518 responded to both screener questions related to PDP prevalence (Q10 and Q11) and were included in the analysis to estimate prevalence. In this subset, 1,197 (79%) described their primary specialty as neurology and 74 (5%) described their primary specialty as psychiatry. The remaining 247 participants (16%) described their primary specialty as general practice, family practice, internal medicine, geriatrics or 'other'. Of the participants included in the prevalence analysis, 758 (50%) primarily practised in the academic/teaching hospital setting, 415 (27%) primarily practised in an office or clinic setting, and 319 (21%) primarily practised at a community hospital. The remaining 26 participants (2%) primarily practised in other settings. Country-specific breakdowns of survey participants by primary specialty areas are reported in Table 2.
Only 437 participants (26%) were eligible to take the full patient records survey based on their responses to the screener questions. The number of respondents surveyed by country is reported in Table 3.
Parkinson's disease psychosis prevalence
The 1,518 survey respondents reported seeing and/or treating approximately 285,000 patients with PD over the past 12 months. Participants reported approximately 82,000 of their patients as having a diagnosis of PDP or symptoms of psychosis associated with PD, suggesting a prevalence rate of 29% within the sampled EU-5 cohort. Estimated prevalence rates of PDP or symptoms of psychosis among the PD patient population in each of the five surveyed countries were 30% in France, 27% in Germany, 34% in Italy, 30% in Spain and 21% in the UK. Prevalence and patient numbers by country are presented in Figure 1.
Disruptiveness and comorbidity rates
Based on responses from the 437 neurologists surveyed, an estimated 53% of patients with PDP in the EU-5 cohort exhibit symptoms of psychosis that are disruptive to the patient or their respective caregivers. In the subset of patients with disruptive PDP, an estimated 48% have severe underlying PD motor symptomology while the other 52% have mild-to-moderate symptomology. Comorbidity rates are estimated at 10% for dementia and 7% for CVD among patients with disruptive PDP (not mutually exclusive) and were comparable between those with severe or mild-to-moderate PD motor symptomology.
Surveyed neurologists most often cited interference with patient daily activities (72%), negative impact on patient quality of life (QoL) measures (70%), and negative impact on caregiver QoL measures (59%) as among the top five parameters considered when assessing the disruptiveness of PDP symptoms, although country-to-country variations were identified. Detailed results are presented in Figure 2. Neurologists in Italy and the UK ranked interference with patient daily activities as the top factor considered when assessing disruptiveness of the symptoms of psychosis, while those in Germany and Spain ranked negative impact on patient QoL measures as the top factor. In France, neurologists ranked negative impact on caregiver QoL as the top factor when assessing the disruptiveness of the symptoms of psychosis.
For assessing severity of PD motor symptomology, neurologists surveyed cited interference with patient daily activities (69%), negative impact on patient QoL measures (65%) and impact on walking ability (62%) as the top three factors considered.
PDP is an under-recognised and under-treated condition that commonly manifests in patients with PD that can magnify the overall burden of PD. Treatment options for PDP are distinct from those used to address the hallmark motor symptomology in PD. Current antipsychotic options recommended by European healthcare authorities have non-ideal therapeutic profiles or mixed evidence of efficacy, suggesting a need for therapies without such shortcomings.26–31 Clozapine, for example, requires intensive monitoring due to the risk of serious side effects including agranulocytosis and myocarditis.32 Despite the need, epidemiological data on the prevalence of PDP in Europe are limited, making it difficult for national governments and regulatory authorities to assess the burden of PDP independently from PD, as well as the cost-effectiveness and budget impact of emerging therapies specifically developed to treat PDP. Data on PDP treatment patterns among neurologists in the EU-5 are also limited and are presented in a separate report.33
In the current study, the estimated prevalence rates for PDP among patients with PD in the EU-5 nations are in line with those reported in previous studies.
In prior studies covering the EU-5 nations, reported rates of hallucinations and delusions among patients with PD ranged from 10–45% in France,34–36 13–29% in Germany,37,38 11–32% in Italy,39–41 15–42% in Spain42,43 and 13–55% in the UK.17,44–46 These broad reported ranges highlight the difficulty of carrying out cross-study comparisons. Common variations in study design identified from a targeted literature review (unpublished findings) include the criteria for patient selection, the definition of PDP, the symptoms of psychosis that were of interest to study investigators, differences in the methodology used to assess symptoms, and the timeframe over which symptoms were observed. For example, several studies have reported that inclusion of minor phenomena increases the observed prevalence rate of psychosis symptoms among patients with PD47–49 and that standard assessment tools for PD symptomology, such as the thought disturbance item on the Unified Parkinson Disease Rating Scale (UPDRS) Part I have low sensitivity for capturing such phenomena.50,51 The prevalence rates in the current study were estimated based on survey data reported retrospectively by medical practitioners. Most respondents are likely to have used standard diagnostic criteria, clinical judgment and assessment tools to diagnose PDP and symptoms of psychosis. The need to modify existing diagnostic criteria and assessment tools for PDP to capture minor phenomena is discussed elsewhere in the literature.5,47,50
The 29% estimated prevalence rate for PDP in the EU-5 overall also aligns with the 12-year longitudinal population study in Norway reporting the 18–49% range for point prevalence of PDP,25 suggesting the current study results could be useful for approximating PDP prevalence in other European nations.
Survey participants were asked to stratify the composition of their respective patient pools by disruptiveness of symptoms, severity of underlying PD motor symptomology and the presence of select comorbidities; such data could facilitate future studies to elucidate differences in treatment patterns based on the presence or absence of these clinical factors. In the current study, the estimated 53% rate for disruptive psychosis among patients with PDP was based on responses from the subset of neurologists who participated in the survey. Multiple studies in patients with PD have documented the negative impact of psychosis on QoL measures in individual European nations,19,52–55 but to the best of our knowledge, the rates of disruptive versus non-disruptive psychosis among patients with PDP have not been previously reported for the EU-5. Additional areas for future research include stratification by stage of PD and by suspected drivers of PDP symptoms (e.g., drug-induced versus not drug-induced).
Data from the current study suggests the 1,518 respondents to the screener questions extended care to approximately 285,000 patients with PD across the EU-5 nations in the 12 months since they participated in the survey. A 2015 market research study reported an estimated 1.3 million patients with PD in the EU-5 nations,4 which suggests the current study captured over 20% of the total PD patient population across this region. Together with the current findings, we estimate approximately 370,000 patients with PDP in the EU-5.
It is important to note that estimated prevalence rates from the current study are based on estimates provided by respondents to an online survey, and are retrospective by nature. Moreover, the identification of PDP, its associated symptoms and various comorbidities are based on the assessment of the survey participant and are subject to local and regional variations in clinical practice. The survey did not control for country-specific variations in guideline recommendations, diagnostic criteria and assessment tools that medical practitioners use to diagnose PDP or symptoms of psychosis in their PD patients. In addition, the survey did not control for the possibility of multi-counting patients. It is possible a patient will visit a neurologist for PD motor symptomology and a psychiatrist for psychosis-related symptomology, and it remains possible for survey respondents to multi-count patients who came in for care multiple times over a 12 month timeframe when providing estimates. Although instructions to not multi-count patients from multiple consultations were provided, the level of compliance could not be determined. With respect to survey questions, Q10 from the screener questions asked survey respondents to include patients with symptoms of psychosis associated with PD when providing their estimates, which could be a broader definition of PDP than what is described in current guidelines from European healthcare authorities. Moreover, responses from Q1 and Q3 from the full survey are based on neurologists' assessments of what they consider to be disruptive versus non-disruptive psychosis and severe versus mild-to-moderate PD motor symptomology, which includes a degree of subjectivity. Reasonable efforts were made during the survey design, targeting and analysis steps to preserve the integrity of the collected data. The estimated prevalence from the current study align with those reported in prior studies suggesting survey respondents answered questions in good faith and that data integrity was not significantly compromised.
No other study to date has assessed the prevalence of PDP in the EU-5 using a consistent methodology that would enable straightforward comparison of prevalence rates between countries. Results of the current study provide a resource that enables cross-country comparison of PDP rates across these major European nations and could potentially be used in studies to estimate the prevalence of PDP across the broader EU. The results also could facilitate studies to assess the burden of PDP and cost effectiveness of emerging new therapies independently of PD. A report of survey data related to treatment patterns for patients with PDP in the EU-5 is presented in a separate report.
Keziah Cook and Kai-Jye Lou are employees
of Analysis Group Inc., which has received research
grants from ACADIA Pharmaceuticals Inc. Rathi Suresh is
an employee at BluePrint Research Group LLC, which has
received research grants from ACADIA Pharmaceuticals
Inc. J Patrick Kesslak and Doral Fredericks are
employees of ACADIA Pharmaceuticals Inc.
Compliance With Ethics
All procedures were followed in accordance with the responsible committee on human experimentation and with the Helsinki Declaration of 1975 and subsequent revisions.
Double-blind peer review.
All named authors meet the International
Committee of Medical Journal Editors (ICMJE) criteria
for authorship of this manuscript, take responsibility
for the integrity of the work as a whole, and have
given final approval to the version to be published.
Doral Fredericks,
ACADIA Pharmaceuticals Inc., 3611 Valley
Centre Drive, Suite 300, San Diego, CA 92130,
USA. E: dfredericks@acadia-pharm.com
The publication of this article was
supported by ACADIA Pharmaceuticals Inc.
This article is published under the
Creative Commons Attribution Noncommercial License,
which permits any non-commercial use, distribution,
adaptation and reproduction provided the original
author(s) and source are given appropriate credit.
Survey assistance was provided by Sonia Gulati, formerly at BluePrint Research Group.
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Martinez-Martin P, Rodriguez-Blazquez C, Forjaz MJ, et al., Neuropsychiatric symptoms and caregiver's burden in Parkinson's disease, Parkinsonism Relat Disord, 2015;21:629–34.
Gibson G, Mottram PG, Burn DJ, et al., Frequency, prevalence, incidence and risk factors associated with visual hallucinations in a sample of patients with Parkinson's disease: a longitudinal 4-year study, Int J Geriatr Psychiatry, 2013;28:626–31.
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Schrag A, Hovris A, Morley D, et al., Caregiver-burden in parkinson's disease is closely associated with psychiatric symptoms, falls, and disability, Parkinsonism Relat Disord, 2006;12:35–41.
Marsh L, Williams JR, Rocco M, et al., Psychiatric comorbidities in patients with Parkinson disease and psychosis, Neurology, 2004;63:293–300.
Klein C, Prokhorov T, Miniovitz A, et al., Admission of Parkinsonian patients to a neurological ward in a community hospital, J Neural Transm (Vienna), 2009;116:1509–12.
McLaughlin NCR, Piryatinsky I, Epstein-Lubow G, et al., Neuropsychiatric symptoms in an inpatient Parkinson's disease sample, Parkinson's Dis, 2014:420240.
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Aarsland D, Larsen JP, Tandberg E, Laake K, Predictors of nursing home placement in Parkinson's disease: A population‐based, prospective study, J Am Geriatr Soc, 2000;48:938–42.
Forsaa E, Larsen JP, Wentzel-Larsen T, et al., A 12-year population-based study of psychosis in Parkinson disease, Arch Neurol, 2010;67:996–1001.
Ondo WG, Tintner R, Voung KD, et al., Double-blind, placebo-controlled, unforced titration parallel trial of quetiapine for dopaminergic-induced hallucinations in Parkinson's disease, Mov Disord, 2005;20:958–63.
Rabey JM, Prokhorov T, Miniovitz A, et al., Effect of quetiapine in psychotic Parkinson's disease patients: a double-blind labeled study of 3 months' duration, Mov Disord, 2007;22:313–8.
Kurlan R, Cummings J, Raman R, et al., Quetiapine for agitation or psychosis in patients with dementia and parkinsonism, Neurology, 2007;68:1356–63.
Shotbolt P, Samuel M, Fox C, David AS, A randomized controlled trial of quetiapine for psychosis in Parkinson's disease, Neuropsychiatr Dis Treat, 2009;5:327–332.
Fernandez HH, Okun MS, Rodriguez RL, et al., Quetiapine improves visual hallucinations in Parkinson disease but not through normalization of sleep architecture: results from a double-blind clinical-polysomnography study, Int J Neurosci, 2009;119:2196–205.
Raja M, Raja S, Clozapine safety, 40 years later, Current Drug Safety, 2014;9:163–95.
Novartis Pharmaceuticals, Prescribing Information for Clozaril® (clozapine), East Hanover, NJ: Novartis Pharmaceuticals Corporation, 2015.
Cook K, Suresh R, Lou K-J, et al., Parkinson's disease psychosis – patterns of care and treatment in the EU-5 from the neurologists' perspective, Eur Neurol Rev, 2017;12:92–9.
Bannier S, Berdagué JL, Rieu I, et al., Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease, J Neurol Neurosurg Psychiatry, 2012;83:1019–21.
Debs R, Cochen De Cock V, Nègre-Pagès L, et al., Thought disorders among non-demented outpatients with Parkinson's disease: prevalence and associated factors, J Neural Transm (Vienna), 2010;117:1183–88.
Fénelon G, Alves G, Epidemiology of psychosis in Parkinson's disease, J Neurol Sci, 2010;289:12–7.
Riedel O, Klotsche J, Spottke A, et al., Frequency of dementia, depression, and other neuropsychiatric symptoms in 1,449 outpatients with Parkinson's disease, J Neurol, 2010;257:1073–82.
Kasten M, Kertelge L, Brüggemann N, et al., Nonmotor symptoms in genetic Parkinson disease, Arch Neurol, 2010;67:670–6.
Morgante L, Colosimo C, Antonini A, et al., Psychosis associated to Parkinson's disease in the early stages: relevance of cognitive decline and depression, J Neurol Neurosurg Psychiatry, 2012;83:76–82.
Poletti M, Perugi G, Logi C, et al., Dopamine agonists and delusional jealousy in Parkinson's disease: a cross-sectional prevalence study, Mov Disord, 2012;27:1679–82.
Pacchetti C, Manni R, Zangaglia R, et al., Relationship between hallucinations, delusions, and rapid eye movement sleep behavior disorder in Parkinson's disease, Mov Disord, 2005;20:1439–48.
Pagonabarraga J, Martinez-Horta S, Fernández de Bobadilla R, et al., Minor hallucinations occur in drug-naive Parkinson's disease patients, even from the premotor phase, Mov Disord, 2016;31:45–52.
García-Escrig M, Bermejo Pareja F, Fernández Ponsatí JT, Psicosis por levodopa en pacientes con enfermedad de Parkinson idiopática, Medicina Clínica, 1999;112:245–50.
Urwyler P, Nef T, Killen A, et al., Visual complaints and visual hallucinations in Parkinson's disease, Parkinsonism Relat Disord, 2014;20:318–22.
Leroi I, Pantula H, McDonald K, Harbishettar V, Neuropsychiatric symptoms in Parkinson's disease with mild cognitive impairment and dementia, Parkinsons Dis, 2012;2012:308097.
McAuley JH, Gregory S, Prevalence and clinical course of olfactory hallucinations in idiopathic Parkinson's disease, J Parkinsons Dis, 2012;2:199–205.
Fénelon G, Soulas T, Zenasni F, De Langavant LC, The changing face of Parkinson's disease‐associated psychosis: A cross‐sectional study based on the new NINDS‐NIMH criteria, Mov Disord, 2010;25:763–6.
Mack J, Rabins P, Anderson K, et al., Prevalence of psychotic symptoms in a community-based Parkinson disease sample, Am J Geriatr Psychiatry, 2012;20:123–32.
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redpajama_set_name: RedPajamaCommonCrawl


Amatitán shopping centers online – database of shopping areas in Amatitán (Jalisco, Mexico). Information about shopping centers, malls, factory outlet locations in Amatitán (Jalisco).
Select Amatitán shopping areas from the list. All Amatitán (Jalisco) shopping centers, malls are displayed on the map.


Claudio Agostini, 2006. "Estimating Market Power in the US Copper Industry," Review of Industrial Organization, Springer;The Industrial Organization Society, vol. 28(1), pages 17-39, February.
Juan-Pablo Montero & Juan Ignacio Guzman, 2010. "OUTPUT-EXPANDING COLLUSION IN THE PRESENCE OF A COMPETITIVE FRINGE -super-," Journal of Industrial Economics, Wiley Blackwell, vol. 58(1), pages 106-126, March.
Pothen, Frank, 2013. "The metal resources (METRO) model: A dynamic partial equilibrium model for metal markets applied to rare earth elements," ZEW Discussion Papers 13-112, ZEW - Leibniz Centre for European Economic Research.
Pieroni, Luca & Ricciarelli, Matteo, 2008. "Modelling dynamic storage function in commodity markets: Theory and evidence," Economic Modelling, Elsevier, vol. 25(5), pages 1080-1092, September.
Luca Pieroni & Matteo Ricciarelli, 2005. "Modelling Dynamic Storage Function in Commodity Markets:Theory and Evidence," Quaderni del Dipartimento di Economia, Finanza e Statistica 11/2005, Università di Perugia, Dipartimento Economia.
Li, Haizheng & Luo, Jifeng, 2008. "Industry consolidation and price in the US linerboard industry," Journal of Forest Economics, Elsevier, vol. 14(2), pages 93-115, April.
Cynthia Lin, C.-Y. & Wagner, Gernot, 2007. "Steady-state growth in a Hotelling model of resource extraction," Journal of Environmental Economics and Management, Elsevier, vol. 54(1), pages 68-83, July.
Luca Pieroni & Matteo Ricciarelli, 2005. "Testing rational expectations in primary commodity markets," Applied Economics, Taylor & Francis Journals, vol. 37(15), pages 1705-1718.
Christopher Snyder, 2006. "Introduction to the 2005 International Industrial Organization Conference Special Issue," Review of Industrial Organization, Springer;The Industrial Organization Society, vol. 28(1), pages 1-2, February.
Pothen, Frank, 2014. "Dynamic market power in an exhaustible resource industry: The case of rare earth elements," ZEW Discussion Papers 14-005, ZEW - Leibniz Centre for European Economic Research.
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:kap:revind:v:28:y:2006:i:1:p:17-39. See general information about how to correct material in RePEc.


The Google Search Appliance was effectively schemaless and required no mapping of content source fields and metadata to an internal schema. The schema-less design is in complete contrast to every other search index. Through the many migrations that we've performed in the past year, we've noticed an emergent pattern where our customers have difficulty relating to this.
Isn't our new system is schemaless?
Not true, even Google's Big Table is not "schemaless." If you look at Google's product documentation for Big Table, they describe their product as being "schemaless." Modern indexes allow for the definition of field types and templates for fields. This definition capability means that a document does not have to contain all of the fields that are defined in the index for the document to be indexed. Adding of additional fields can be done dynamically and not require purging of the index and reindexing. This feature is de facto among modern insight engines. Just know, to be most successful you should take on the work of defining your schema.
What do we have to define?
We typically start with the user interface and work backward to the data. With this approach, you start with the search wireframe and examine the data elements that are or are expected to drive the interface. Data points that are typical include facet fields search result attributes and autocomplete. Once you have these defined, we then map these to the type of fields required in the index. Facets are typically "stored" or have some similar attribute for example.
How do we assemble the various sources?
Ideally, you don't. As every data scientist knows, as part of the extract-transform-load (ETL) process is normalizing your data into standard fields. Normalization, in this case, means that you move the "owa_Author" field that you get from Sharepoint and the "createdby" field that you get from Confluence into a defined schema field like "author." We have created a field mapping spreadsheet which you can use on your project. With this spreadsheet, we run a script to create the necessary field definitions.
Once the data is in the correct field, we then work on a standard form. The standard form is vital because "insight engine" and "Insight Engine" are two entirely different facets.
Can I get a copy of your template?
You can request to download the spreadsheet by filling out the form on this page. You'll be sent a link to a Google Spreadsheet which you can copy or export. Keep that link handy as it will update it over time based on the feedback we receive.
I'm interested in receiving additional marketing materials related to products and services from MC+A. I may withdraw my consent at any time by contacting MC+A at no cost to me.


text:
package org.apache.nutch.webui;

import org.apache.commons.cli.CommandLine;
import org.apache.commons.cli.CommandLineParser;
import org.apache.commons.cli.GnuParser;
import org.apache.commons.cli.HelpFormatter;
import org.apache.commons.cli.Option;
import org.apache.commons.cli.OptionBuilder;
import org.apache.commons.cli.Options;
import org.apache.hadoop.util.StringUtils;
import org.apache.wicket.protocol.http.WicketFilter;
import org.apache.wicket.spring.SpringWebApplicationFactory;
import org.mortbay.jetty.Handler;
import org.mortbay.jetty.Server;
import org.mortbay.jetty.servlet.Context;
import org.mortbay.jetty.servlet.DefaultServlet;
import org.mortbay.jetty.servlet.FilterHolder;
import org.springframework.web.context.ContextLoaderListener;
import org.springframework.web.context.WebApplicationContext;
import org.springframework.web.context.request.RequestContextListener;
import org.springframework.web.context.support.AnnotationConfigWebApplicationContext;

public class NutchUiServer {
  private static final String APP_FACTORY_NAME = SpringWebApplicationFactory.class
      .getName();
  private static final String CONFIG_LOCATION = "org.apache.nutch.webui";
  private static final String CMD_PORT = "port";
  private static Integer port = 8080;

  public static void main(String[] args) throws Exception {
    CommandLineParser parser = new GnuParser();
    Options options = createWebAppOptions();
    CommandLine commandLine = null;
    HelpFormatter formatter = new HelpFormatter();
    try {
      commandLine = parser.parse(options, args);
    } catch (Exception e) {
      formatter.printHelp("NutchUiServer", options, true);
      StringUtils.stringifyException(e);
    }

    if (commandLine.hasOption("help")) {
      formatter.printHelp("NutchUiServer", options, true);
      return;
    }
    if (commandLine.hasOption(CMD_PORT)) {
      port = Integer.parseInt(commandLine.getOptionValue(CMD_PORT));
    }
    startServer();
  }

  private static void startServer() throws Exception, InterruptedException {
    Server server = new Server(port);
    Context context = new Context(server, "/", Context.SESSIONS);
    context.addServlet(DefaultServlet.class, "/*");

    context.addEventListener(new ContextLoaderListener(getContext()));
    context.addEventListener(new RequestContextListener());

    WicketFilter filter = new WicketFilter();
    filter.setFilterPath("/");
    FilterHolder holder = new FilterHolder(filter);
    holder.setInitParameter("applicationFactoryClassName", APP_FACTORY_NAME);
    context.addFilter(holder, "/*", Handler.DEFAULT);

    server.setHandler(context);
    server.start();
    server.join();
  }

  private static WebApplicationContext getContext() {
    AnnotationConfigWebApplicationContext context = new AnnotationConfigWebApplicationContext();
    context.setConfigLocation(CONFIG_LOCATION);
    return context;
  }

  private static Options createWebAppOptions() {
    Options options = new Options();
    Option helpOpt = new Option("h", "help", false, "show this help message");
    OptionBuilder.withDescription("Port to run the WebApplication on.");
    OptionBuilder.hasOptionalArg();
    OptionBuilder.withArgName("port number");
    options.addOption(OptionBuilder.create(CMD_PORT));
    options.addOption(helpOpt);
    return options;
  }

}


Nnenna Okoye is a beauty enthusiast and CEO of online beauty retail store, Youtopia Beauty, which specialises in selling hard-to-find beauty products mainly for the African skin. She has bagged herself a beauty certification from a renowned beauty school, the beauty academy in London, where she specialized in skincare.
Nigeria's beauty sector is expanding and thriving. Amidst economic challenges, the sector has maintained its growth among other industries. The demand for skin care, oral care, hair and makeup products has soared. This has thus made the business of beauty a very lucrative business in Nigeria. Similarly, online transactions have become a dominant trend in Nigeria. There is no doubt that shopping online is very convenient for people. Individuals can shop from any and every location, provided there is internet connection and access to a computer, tablet device or Smartphone. Moreover, online shopping allows people to easily compare products, prices and items across shops online to validate if a product seen on a particular shops website is more affordable or better than the other and vice versa.
Online retail in Nigeria has evolved. It is the latest way of buying items on the internet by shoppers all over Nigeria. "I noticed that there were not a lot of options in Nigeria and many people, including me, relied on products sold abroad. Skincare products were not largely sold online, compared to makeup and hair products. So, I decided to make it easier for people looking for very specific brands by starting an online retail business that focuses more on skin care, although not neglecting hair and makeup products." The online beauty store also offers free online Virtual Consultation. A skincare consultation set up to help as many people as possible suffering with skin problems like acne. These severe skin problems lead to low self-esteem and lack of confidence. Thus, the aim of the online consultation is to reach a broader audience; people from different parts of Nigeria and Africa, as a whole.
In regards to technology, Nnenna explained that it has made online shopping convenient, fast, accessible and stress-free experience for customers. It provides businesses with the platform to understand the needs of their customers and better satisfy those needs. No doubt, a happy, satisfied, and returning customer leads to more profit for a business. Through interactive and personalized product displays, online retail has been able to thrive. The evolution of technology within the retail and e-commerce sector is shaping how consumers behave and interact with different brands. For instance, when customers make an online transaction, the retailer gets data about the customer. This data includes the type and number of products a particular customer purchased. An accumulation of this information enables the retailer to have an understanding of the pattern of inventory flow of products and this helps in getting the required items and prevents preferred products to be out of stock.


Because tomorrow is a holiday, your sales order will be processed the following business day.
Urgent payout is available up until € 10,000. Contact us to discuss the possibilities for larger amounts.
The bitcoins you wish to sell have been acquired in a legal manner.


text:
S&W M&P 5" .40 Pro Series Holsters
Smith & Wesson M&P 5" .40 Pro Series Holsters
The Smith & Wesson M&P 5" .40 Pro Series is a striker fire pistol with a Picatinny style rail. It features interchangeable grip sizes and an ambidextrous slide stop. This model does not have a thumb safety.
This Smith & Wesson model weighs only 28.5 ounces unloaded and has a barrel length of 127 mm or 5 inches.
Each holster listed above is able to be handmade for the Smith & Wesson M&P M&P 5" .40 Pro Series. With our many color options, clip sizes, and hand orientation options, you can customize a holster to you and your gun. Our most popular Smith & Wesson M&P 5" .40 Pro Series holster, the Vedder LightTuck™ IWB Holster, is a great option for concealed carrying this Smith & Wesson model.
If you have additional questions about specs or holsters contact us at 352.729.6749.
Smith & Wesson M&P 5" .40 Pro Series Specifications
The Smith & Wesson M&P 5" .40 Pro Series has a length of 216 mm or 8.5 inches.
This Smith & Wesson M&P 5" Pro Series model has a caliber of 40 S&W.


Our standard case, in a hard-wearing plastic material. Supplied with all spectacles that don't have their own case. We may alternatively supply our small case or our premium case if we feel they fit your glasses better. Get an extra one for just £2.95.


I am having second thoughts. Recently I set in motion a plan to move from a 6700k to an 8700k on my ASUS Z170-A board. I need some more power and I thought this would be the cheapest and maybe "fun" way to get more power. However now I am not so sure. There is a real risk I brick my z170 board flashing a modded bios to it. I have been thinking I should have a Z390-a board on hand in case worse comes to worse and the z170-a dies. After all I NEED my rig running. That of course means potentially spending 250 on a new board and maybe killing a working board?? I am not sure my level of enthusiasm is where it used to be with puter parts and tinkering. What to do what to do. Wait for Zen2 (16C32T on x470)? Hold fast with little ol 6700k? Throw caution and money to the wind and try the 8700k and see where that takes me?
So ya. I have asked a question that only I will be able to answer in the end. Just thought I would bounce it off of some other people as it is snowing, cold and I am bored.
My use case is such that my 6700k is always running at ~20-30% usage. I need more cores. The 8700k I have coming will do 5.1-5.2 according to its seller... I have no idea what I am doing anymore.
Simple sell the 6700k/Z170 and get a used if possible z370 board. Ride that for a while at a minimum loss. Then if so inclined switch over to Ryzen2 in April/ May when available. I believe it's possible to lose both the z170 and 8700k if unsuccessful and as I posted in your other thread I haven't seen in my reading any success with that particular board.
What are you running that is constant 20-30% cpu?
Sorry for the slow reply. I am running Security Monitor Pro. It monitors my IP cams.
I have modded and flashed a bios to my z170-a but I am having issues with the LGA pin mod on my coffee lake cpu. I hope to report soon that I have an 8700k working on my Z170-A. If not I will want to buy a z370/390 board.
@Mightyunit nice good job on the bios mod and good luck with the pin mod as I know those tiny pins are not great to work with.
I thought it was something done to the base of the CPU?
It looks to be an issue remaining within the bios that I hope to soon get straightened out. I was reassured that it is not the mod to the CPU that is currently at fault.


text:
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Author: J Simard x
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17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes
H Peltoketo, V Luu-The, J Simard, and J Adamski
A number of enzymes possessing 17beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase (17HSD/KSR) activities have been described and cloned, but their nomenclature needs specification. To clarify the present situation, descriptions of the eight cloned 17HSD/KSRs are given and guidelines for the classification of novel 17HSD/KSR enzymes are presented.
Effects of sex steroids on regulation of the levels of Cl peptide of rat prostatic steroid-binding protein mRNA evaluated by in-situ hybridization
G. Pelletier, C. Labrie, J. Simard, M. Duval, M. G. Martinoli, H. Zhao, and F. Labrie
Prostatic steroid-binding protein (PBP) is the most abundant protein synthesized in the rat ventral prostate. The protein is under strict androgenic control and is made of two subunits containing the polypeptides Cl, C2 and C3. Using an 35S-labelled cDNA probe, we have used quantitative in-situ hybridization to assess the regulation of polypeptide Cl mRNA levels by sex steroids in the adult male rat. Densitometric quantification of autoradiographic hybridization signals revealed that a significant decrease in Cl mRNA levels could be detected 5 h after castration. Levels of Cl mRNA decreased by 50% 2·5 days after castration, while undetectable levels were reached within 7 days. Administration of the potent androgen 5α-dihydrotestosterone to castrated rats caused a progressive increase in Cl mRNA levels which became significant 5 h after the first injection, while prolonged treatment, for 3 and 7 days, caused 50 and 100% reversals respectively of the effect of castration on Cl mRNA levels. Similar results were obtained by dot-blot hybridization using the same 32P-labelled cDNA probe, thus confirming the specificity and quantification achieved by in-situ hybridization. Administration of oestradiol-17β to orchiectomized adult rats for 14 days had no effect on steady-state Cl mRNA levels. Progesterone, on the other hand, at the dose used (2 mg twice daily) caused a marked increase in Cl mRNA levels, measured by in-situ hybridization, which was completely reversed by concomitant administration of the pure antiandrogen flutamide.
The present data clearly demonstrate that the expression of PBP Cl peptide mRNA is under strict androgenic control and is a very sensitive and specific parameter of androgenic activity. They also indicate that quantitative in-situ hybridization is a powerful, sensitive and most efficient tool to study the regulation of gene expression while, in addition, providing precise information about the site of mRNA localization as well as information about the histology of the tissue, particularly the heterogeneous nature of the acinar response to androgenic stimulation and deprivation.
Intracrinology: role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease
F Labrie, V Luu-The, SX Lin, J Simard, C Labrie, M El-Alfy, G Pelletier, and A Belanger
In women and men, an important proportion of estrogens and androgens are synthesized locally at their site of action in peripheral target tissues. This new field of endocrinology has been called intracrinology. In postmenopausal women, 100% of active sex steroids are synthesized in peripheral target tissues from inactive steroid precursors while, in adult men, approximately 50% of androgens are made locally in intracrine target tissues. The last and key step in the formation of all estrogens and androgens is catalyzed by members of the family of 17beta-hydroxysteroid dehydrogenases (17 beta-HSDs) while different 17 beta-HSDs inactivate these steroids in the same cell where synthesis takes place. To date, seven human 17 beta-HSDs have been cloned, sequenced and characterized. The 17 beta-HSDs provide each cell with the means of precisely controlling the intracellular concentration of each sex steroid according to local needs.
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Jharkhand District List
Gumla District
Gumla Population
Gumla Town Population Census 2011 - 2023
Gumla is a Nagar Panchayat city in district of Gumla, Jharkhand. The Gumla city is divided into 20 wards for which elections are held every 5 years. The Gumla Nagar Panchayat has population of 51,264 of which 26,252 are males while 25,012 are females as per report released by Census India 2011.
Population of Children with age of 0-6 is 6373 which is 12.43 % of total population of Gumla (NP). In Gumla Nagar Panchayat, Female Sex Ratio is of 953 against state average of 948. Moreover Child Sex Ratio in Gumla is around 925 compared to Jharkhand state average of 948. Literacy rate of Gumla city is 89.33 % higher than state average of 66.41 %. In Gumla, Male literacy is around 93.02 % while female literacy rate is 85.48 %.
Gumla Nagar Panchayat has total administration over 9,724 houses to which it supplies basic amenities like water and sewerage. It is also authorize to build roads within Nagar Panchayat limits and impose taxes on properties coming under its jurisdiction.
Gumla 2022 - 2023 Population
Current estimated population of Gumla Nagar Panchayat in 2023 is approximately 69,000. The schedule census of 2021 for Gumla city is postponed due to covid. We believe new population census for Gumla city will be conducted in 2023 and same will be updated once its done. The current data for Gumla town are estimated only but all 2011 figures are accurate.
Gumla Caste Factor
Gumla (NP) of Gumla has substantial population of Schedule Tribe (ST). Schedule Tribe (ST) constitutes 34.94 % while Schedule Caste (SC) were 4.89 % of total population in Gumla (NP).
Gumla Work Profile
Out of total population, 14,090 were engaged in work or business activity. Of this 11,044 were males while 3,046 were females. In census survey, worker is defined as person who does business, job, service, and cultivator and labour activity. Of total 14090 working population, 84.49 % were engaged in Main Work while 15.51 % of total workers were engaged in Marginal Work.
Gumla Population Religion Data
Hindu 45.93%
Muslim 20.35%
Christian 18.27%
Sikh 0.31%
Buddhist 0.07%
Jain 0.01%
Others 14.95%
No Religion 0.10%
Gumla City Ward List
1 Gumla Ward No - 1 2548
10 Gumla Ward No - 10 1890
12 Gumla Ward No - 12 816
Gumla City/Town Future Population 2021-2031
Gumla City


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Volume 2 Issue 9 - May 01, 2004
Protest outside EC office; several activists detained
DNIS News Network -- Several activists from Disabled Rights Group (DRG) were detained while protesting outside the Election Commission office on April 15. The activists were demanding Braille script for EVMs and ramps to provide entry into the polling booths.
About 400 disabled rights activists protested in front of Jantar Mantar and then moved on to the Election Commission Office. The Delhi Police officials tried to prevent them from meeting the Chief Election Commissioner TS Krishnamurthy at his office in Nirvachan Sadan and resorted to force to disperse the gathering. Several protestors were detained when they blocked the road and stopped traffic movement for about 45 minutes.
Election Commission officials were unmoved by the demonstration and refused to meet the protestors to hear their plea. However, after much persuasion, a delegation of activists finally managed to hand over the memorandum to an official, who promised to pass it to Mr. Krishnamurthy. The demonstrations continued late into the afternoon even as the police tried forcefully to pack the disabled in their vehicles.
Meanwhile DRG convener, Javed Abidi, continued his fast unto death for the second consecutive day against the EC's " apathetic attitude" to polling station access for disabled voters.
On the election trail
Rites of passage in India
PIL requests Chief Justice to intervene in the access order
Javed Abidi files nomination to stand as an independent candidate
CJI takes up access issue
SC orders ramps for polling booths in cities
Disabled celebrate verdict on ramps
Incidence of disability declining says NSSO survey
Sponsored worldwide bikers raise funds for ORBIS in Delhi
Shortage of teachers for disabled people
Disabled teenager conquers North Pole


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Metinvest B.V. (the Netherlands), the parent company of the international vertically integrated mining and metallurgical group Metinvest, has become a member of the Dutch Association of Metallurgical Industry (VNMI). According to a press release from the company, the trade association of Dutch producers of raw materials, semi-finished goods and finished steel products VNMI was established in 2000, uniting more than 80% of the players in the steel industry in the Netherlands.
The association represents Dutch steelworkers in European business associations in The Hague and Brussels. VNMI focuses on four areas: health and safety, energy and climate, sustainability and corporate social responsibility, trade and innovation.
It is noted that Metinvest Group has been developing these areas since its creation. The company supports global initiatives and participates in international environmental projects. In 2010, Metinvest joined the UN Global Compact.
DUTCH ASSOCIATION, METALLURGICAL INDUSTRY, METINVEST
The State Customs Service on July 16 was registered in the unified state register of legal entities, individual entrepreneurs and public organizations of the Ministry of Justice. "When you enter the register and you are happy. Today Maksym Nefyodov [the head of the State Customs Service appointed as a result of a tender] has registered the State Customs Service," Finance Minister Oksana Markarova said on Facebook.
As reported, on July 13 Nefyodov completed his work as deputy minister of economic development and trade and from July 15 began to serve as head of the customs service.
The government of Ukraine in December 2018 decided to divide the State Fiscal Service into the State Customs Service and the State Tax Service. The State Tax Service was registered earlier, and the creation of the State Customs Service was delayed because of contesting the tender for the head of the department in court.
CUSTOMS SERVICE, JUSTICE MINISTRY, REGISTERS
President of Ukraine Volodymyr Zelensky has ordered that a strategic plan be developed for qualifying to host the Olympic Games in Ukraine. "We need a plan, let's say, that we are ready to build in 3-4 years and then we can get in line to host the Olympics. We must be ambitious," Zelensky put the corresponding task during a conversation with Minister of Youth and Sports Ihor Zhdanov and President of the National Olympic Committee of Ukraine Serhiy Bubka on the territory of the State Enterprise Olympic Educational and Sports Center Koncha Zaspa on Tuesday.
According to the head of state, now we need to develop a sports infrastructure which can then be used for the Olympic Games.
"We should give a task to our guys, who are looking for investments, give a task to our budget, to allocate money annually to the objects we need, and then will be used for the Olympics. At least, we must try to achieve this," Zelensky said.
For his part, Bubka noted that the upcoming Olympic Games for which Ukraine can apply is the 2030 Winter Olympics or the 2032 Summer Olympics.
At the same time, President of the National Olympic Committee of Ukraine noted that it would be more real if we host some of the following Winter or Summer Youth Olympic Games in our country.
OLYMPIC GAMES, ZELENSKY
Aerohandling LLC, engaged in ground service at Boryspil airport (Kyiv), plans to expand the scope of its work towards serving flights at major regional airports in Ukraine and Europe, director general of Aerohandling Oleh Holokhvastov has said in an interview with Interfax-Ukraine.
"We plan enter foreign and Ukrainian regional airports. We are now preparing the company's development strategy and conducting preliminary calculations. It's too early to talk about specifics, as we are in the process of making a decision. We consider major airports in Ukraine and Europe. We plan to start talks this year," he said.
In addition, the company plans to continue developing its facilities in Boryspil: to master the maintenance and transportation of cargo from the aircraft to the warehouse, to work with express mail and express deliveries.
The plans of Aerohandling also include building our own technical base in the restricted area of the airport.
Aerohandling LLC provides ground handling services at Boryspil International Airport.
AEROHANDLING, EUROPEAN AIRPORTS, WORK
Freight transportation on the Dnipro river in January-June 2019 increased by 42% compared to the same period in 2018, to 4.2 million tonnes.
As the Rivers of Ukraine Association reported on Facebook with reference to the Sea Ports Authority of Ukraine, the number of ship passages along the Dnipro decreased by 23%, to almost 4,500 voyages.
Transportation of metals in January-June increased by 45%, to 647,000 tonnes, grain shipments rose by 115.2%, to 1.722 million tonnes, those of building materials and other goods by 7.5% to nearly 1.819 million tonnes. At the same time, fuel transportation decreased by 51%, to 13,000 tonnes.
As reported, 16.5 million tonnes of freight was transported by river in Ukraine in 2018. Freight traffic on the Dnipro last year increased by 22.4% from 2017, to about 9.9 million tonnes.
In 2016-2018, transportation of grain freight across the Dnipro grew by 180% and that of construction freight by 130%, according to the Ministry of Infrastructure of Ukraine.
The volume of traffic by inland waterways in 2016-2018 increased by 112% compared with 2013-2015, to 9.9 million tonnes in 2018.
DNIPRO, FREIGHT TRANSPORTATION, RIVER
UKRAINE RECOGNIZED SAFER THAN USA AND RUSSIA FOR WOMEN TRAVELING ALONE – STUDY
A study of the world's most dangerous countries for women traveling alone reveals the good, the bad and the ugly
There's hearsay. There are personal anecdotes from other travelers. There are specific worries. Then, there are the hard facts. We've gathered data from a variety of trusted international sources to create a "Women's Danger Index" that will help you find the worst (and safest) countries for solo female travel.
At the end of the article we also have 42 tips on how women can stay safe while traveling alone.
Ranking the top 50 countries with the most international tourists by a grand total of eight different factors, our "Women's Danger Index" was compiled using the following data sources:
Gallup World Poll (2018): Percentage of women who feel safe walking alone at night = 2 points
Equal Measures 2030 (2018): Female victims of intentional homicide index = 2 points
UN Women (2016): Lifetime Non-Partner Sexual Violence = 1 point
Georgetown Institute (2017/2018): Lifetime Intimate Partner Violence = 1 point
Georgetown Institute (2017/2018): Legal Discrimination = 1 point
World Economic Forum (2017): Global Gender Gap = 1 point
UN Development Program (2017): Gender Inequity = 1 point
OECD (2018): Attitudes Toward Violence Against Women Survey = 1 point
To measure safety abroad, one cannot look at only data on street safety, rape or violence. It also depends on the general attitude of the culture, minutiae of the legal system, and systematic oppression of local women. These issues can affect everything, from easily getting a taxi alone to having your voice be heard in a conversation to even needing a male escort for your personal safety. A lot on our list, such as attitudes toward partner violence, may not affect solo female travelers directly, but these factors are a good indication of overall attitudes within the culture.
Sadly, not one country received an "A" which indicates we have a long way to go before there is true equality between men and women on Earth. Thankfully, there are many signs that things are improving and there is light at the end of the tunnel.
Please note: We gave both the "percentage of women who feel safe walking alone at night" and the "female victims of intentional homicide index" a double weighting score because they are very good indicators of safety for foreign female travelers and are more likely to be highly accurate since it isn't "shameful" to admit. Whereas, non-partner and intimate partner sexual violence are obviously strong indicators for rape but the seriously widespread underreporting (to differing degrees per country) makes it hard to justify double weight because it could skew the results more than is fair.
RUSSIA, SAFER, TRAVELING ALONE, UKRAINE, USA, WOMEN


text:
const { responseError, responseSuccess, getOrderTable, constructShopifyBody, postToShopify, putToShopify, getCardName } = require('../helpers/utils');
module.exports = [{
  path: '/api/savetodb',
  method: 'post',
  handler: (req, res) => {
    console.log("Received post request from Cybersource and save to DB endpoint...")
    const params = req.body
    let company = ""
    let billing_company = ""
    let ship_to_address_line2 = ""
    let bill_to_address_line2 = ""
    const shopifyURL = 'https://city-cosmetics.myshopify.com/admin/orders.json'
    let shopifyBody = {}
    if (params.reason_code == '100') {
      const checkout_id = params.req_merchant_defined_data5
      const amount = params.req_amount
      const click_id = params.req_merchant_defined_data6
      const phone = params.req_ship_to_phone
      const card_number = params.req_card_number
      const card_name = getCardName(params.req_card_type)

      let order_type = ""
      let tags = ""
      let note = ""
      let line_items = []
      let tax_lines = []
      let variant_arr = []
      let note_attributes = []
      let shopify_order_id = ""
      let shopify_order_name = ""

      const customer = {
        "first_name": params.req_ship_to_forename,
        "last_name": params.req_ship_to_surname,
        "email": params.req_bill_to_email
      }

      const product = {
        "variant_id": params.req_merchant_defined_data7,
        "quantity": params.req_merchant_defined_data12,
        "discount_amount": params.req_merchant_defined_data13
      }

      //check if those optional fields are blank
      if (params.req_ship_to_company_name) {
        company = params.req_ship_to_company_name
      }

      if (params.req_bill_to_company_name) {
        billing_company = params.req_bill_to_company_name
      }

      if (params.req_ship_to_address_line2) {
        ship_to_address_line2 = params.req_ship_to_address_line2
      }

      if (params.req_bill_to_address_line2) {
        bill_to_address_line2 = params.req_bill_to_address_line2
      }

      const shipping_address = {
        "first_name": params.req_ship_to_forename,
        "last_name": params.req_ship_to_surname,
        "company": company,
        "address1": params.req_ship_to_address_line1,
        "address2": ship_to_address_line2,
        "province": params.req_ship_to_address_state,
        "city": params.req_ship_to_address_city,
        "phone": phone,
        "zip": params.req_ship_to_address_postal_code,
        "country": params.req_ship_to_address_country
      }
      const billing_address = {
        "first_name": params.req_bill_to_forename,
        "last_name": params.req_bill_to_surname,
        "company": billing_company,
        "address1": params.req_bill_to_address_line1,
        "address2": bill_to_address_line2,
        "province": params.req_bill_to_address_state,
        "city": params.req_bill_to_address_city,
        "phone": phone,
        "zip": params.req_bill_to_address_postal_code,
        "country": params.req_bill_to_address_country
      }

      const shipping_amount = params.req_merchant_defined_data8
      const tax_amount = params.req_tax_amount
      const tax_rate = params.req_merchant_defined_data11
      let pmt_token = ""

      if (params.payment_token) {
        pmt_token = params.payment_token
        order_type = "parent order"
        note = "parent order"
        tags = pmt_token

      }
      else {

        pmt_token = params.req_payment_token
        order_type = "upsell order"
        note = "upsell order"
        tags = pmt_token
      }

      variant_arr = params.req_merchant_defined_data7.split(",") // for color combo orders
      if (variant_arr.length > 1) {
        variant_arr.map(variant => {
          line_items.push({"variant_id": variant, "quantity": params.req_merchant_defined_data12})
        })
      }
      else {
        line_items.push({"variant_id": params.req_merchant_defined_data7, "quantity": params.req_merchant_defined_data12})
      }
      tax_lines.push({"price": tax_amount, "rate": tax_rate, "title": "State tax"})
      note_attributes.push({"name": "gateway","value": "CyberSource"},{"name": "card number","value": params.req_card_number},{"name": "card type","value": card_name})
      shopifyBody = constructShopifyBody(line_items,amount,customer,shipping_address,billing_address,tags,note,note_attributes,tax_lines,customer.email,shipping_amount,product.discount_amount)

      console.log("save to DB")
      getOrderTable().put(checkout_id, amount, click_id, customer, shipping_address, billing_address, product, tax_rate, tax_amount, shipping_amount, pmt_token, "CyberSource", order_type, shopify_order_id, shopify_order_name)
      .then(data => {
        console.log("Create order to Shopify")
        return postToShopify(shopifyURL,shopifyBody)
      })
      .then (data => {
        shopify_order_id = data.order.id
        shopify_order_name = data.order.name
        let order_body = {
          "order": {
            "id": data.order.id,
            "metafields": [
              {
                "key": "transaction_id",
                "value": data.order.tags,
                "value_type": "string",
                "namespace": "global"
              }
            ]
          }
        }
        const order_url = `https://city-cosmetics.myshopify.com/admin/orders/${data.order.id}.json`;
        return putToShopify(order_url, order_body)
      })
      .then(data => responseSuccess(res, data))
      .catch((err) => {
        const body = { error_message: `Problem in creating transactions. ${err.display_message}` }
        responseError(res, body)
      })
    }
    else {
      console.log(params.decision)
      console.log(params.message)
      responseError(res, {"transaction": "not successful"})
    }
  }
}];


This was of course the main reason for my visit… to help man the Design Event stand, which showcased new products by 10 designers from the north, including me!
A big thank you to everyone who stopped by our stand for a chat and to browse the work on display. I think you'll agree the stand look fantastic, all thanks to the hard work of Design Event and Xsite Architecture. There will be another chance to see more of our work at the Baltic Centre of Contemporary Art from 26th September until 22nd October.
Whilst exploring DesignJunction, it was great to see so many demonstrations taking place. Waterford were cutting their cut-glass and Bert & May were creating tiles, using the winning design from their 'Design-a-tile' competition with RIBA. A few stands away from us Philippe Malouin were demonstrating their random pattern generator. Visitors could roll dices of geometric shapes and colours to determine which part of the pattern should be printed next.
Starry Light by Anagraphic. This handcrafted lamp illuminates the walls with different starry constellations, and can be customised to a specific date or location. What a perfect birthday or anniversary present this could make!!
Foldability's stand wasn't too far way and her handmade lighting using traditional folding techniques kept catching my eye!
The extravagant brass and fine crystal lighting by Martin Huxford also blew me away.
The Anglepoise & Paul Smith collaboration was another favourite of mine; I think it would sit very nicely on my desk!


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King's College School La Moraleja, recognised as a High-Performance Learning (HPL) World Class School
The school is the first in Spain to achieve this recognition, granted by the High Performance Learning (HPL) organisation in the UK.
King's College School, La Moraleja has become the first High-Performance Learning (HPL) World Class School in Spain. The accreditation, granted by the prestigious High Performance Learning (HPL) organisation in the UK, recognises "schools at the forefront of educational thinking with exceptional outcomes for students" and acknowledges King's College School's "exceptional level of education".
Read full press release here > >
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This is the "N7" edition of the Air Jordan 7 Retro. They come in a white, dark turquoise, black and ice cube blue colorway. Featuring a white-based leather upper with a unique graphic design, finished off by black and turquoise accents, "N7" branding and an icy blue translucent outsole.
In mid-June, Jordan Brand will continue its tradition of global outreach with the Quai 54 streetball tournament, where the continent's best baller squads will compete for the title of supremacy and bragging rights in this heralded hoops extravaganza. As usual, Jordan Brand has some footwear in the works to help celebrate this momentous occasion, and sneakerheads will be pleased to find that the shoes will actually hit retail. The Air Jordan 7 Retro N7 White Dark Turquoise-Black-Ice Cube Blue Men Women with graphic prints inspired by blueprints of the Eiffel Tower, the 2018 Best Sellers in a gum sole an fragmented elephant print, and the all-new Nike LeBron Soldier 9 are the highlights of these Europe-only releases that will hit select retailers on May 30th . Get an official look here and stay tuned to Sneaker News for the latest in 2015 Jordans.


text:
Vehicle Performance Engineering
Powertrain Performance Engineering
Vehicle Electrification Engineering
Autonomous Vehicle Development
Siemens App
Follow #SiemensChip2City on LinkedIn and Twitter to find our latest content daily.
Automotive Performance Engineering
Electric vehicles are a crying need: Steffen Knapp
{data-social}
Electric vehicles are the need of the hour and any mention of alternate fuel vehicles triggers a discussion about the adoption of electric vehicles over traditional internal combustion engine vehicles. The automotive industry is increasingly focussing on reducing greenhouse emissions and this explains the high focus on battery electric vehicles globally.
Steffen Knapp, Director, Volkswagen Passenger Cars India, said the global environmental concerns are far too serious to be ignored and added that time has come to initiate serious action towards creating environmentally-friendly mobility solutions. "Our planet is in danger and the automotive industry is part of the problem – the transportation section accounts for 14 % of the global greenhouse emissions, and we collectively need to address this emission reduction issue," he said.
Read: Moving Beyond Lithium-Ion Batteries for Electric Vehicles
Knaap stated that the acceptance of e-mobility among consumers is increasing continuously. "There are quite a few alternate fuel technologies to explore, but battery electric vehicles appear to be the first choice and the most cost-effective solution to reduce Co2 emissions. OEMs are gradually adopting new energy solutions and e-mobility is rapidly moving from being niche towards a mainstream product," he noted.
He shared his perspective about how electric vehicles have made deeper inroads Europe, especially in Norway. "Norway has been leading by example – 60 % of new cars bought in Norway are EVs and substantial tax incentives offered in the country has enabled a lower purchase price. The German Federal government has set a goal of 1 million EVs by 2020 and 1 million charge points by 2030 and has earmarked € 300 million towards expanding charging infrastructure."
China is another market where EVs are a big draw. "The year 2018 saw most number of EVs sold in China than in the rest of the world combined. The Chinese government has been extremely proactive towards reducing emissions and has spent around $ 60 billion over the last decade to build the EV sector," Knapp noted.
Read: Cost Structure of EVs Has to be Closer to ICE Vehicles: CV Raman
The company has created an independent EV platform - Modular Electric Matrix (MEB) platform – it has infused an investment of around $ 40 billion to develop this platform. "The Modular Electric Matrix (MEB) platform addresses all the key challenges facing EVs such as range anxiety, charging infrastructure and total cost of ownership," he pointed out.
Knapp stressed the need for a stable policy framework. "The government must come up a stable policy framework with precise solutions and gestation periods. There is also a requirement to focus on recycle and reuse of batteries."
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We catch up with some of the most prominent thought leaders in the automotive engineering simulation and testing fraternity to learn more about the latest technology and innovation being offered in the industry. The conversation stories under this section will cover aspects such as automotive simulation technology, advanced driver assistance systems simulation and testing, simulation of driving dynamics and testing parameters, engine systems and controls with system simulation, engine cooling system simulation, hybrid powertrain simulation systems, vehicle PLC and a lot more. To stay informed on the most recent and future developments in the automotive industry, stay tuned to our conversations page. This Knowledge hub is supported by Siemens.
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text:
About Privacy
Camera Surveillance
Regulatory Enforcement
About CBP BES
Personal Data Protection Act BES
The Commission is charged with monitoring whether organizations comply with statutory rules and regulations on personal data use. There are many laws, decrees, and regulations governing personal data processing. The three laws supervised by the Commission are:
•	Personal Data Protection Act BES (PDPA BES);
•	Police Records Act;
•	Act on BES Personal Records in the Caribbean Netherlands.
Personal Data Protection Act BES(PDPA BES)
The Personal Data Protection Act BES (PDPA BES) provides the main rules for dealing with personal data in the Caribbean Netherlands.
Police Records Act
The police uses all sorts of personal data required to properly fulfill its duties, e.g. to investigate perpetrators of criminal offenses. Personal data protection by the police is regulated in the Police Records Act (PRA).
Act on BES Personal Records in the Caribbean Netherlands
A well-functioning population registry in the Caribbean Netherlands is regulated in the BES Personal Records Act. The population register includes personal data of the inhabitants of the Caribbean Netherlands. The BES Personal Records Act regulates the proper use of these data, including the procedure for recording, altering, and disclosing them.
Very many organizations use and exchange personal data….
The police uses all sorts of personal data…
Act on BES Personal Records
The population register includes personal data of the…
Regulation on the protection of natural persons with…
Contact with CBP BES
Data Protection Authority BES
Kaya Pedro Luis Brion 12
Kralendijk, Bonaire
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