#EatForThePlanet This Earth Day With These 10 Recipes That Are Sustainable and Delicious!
How are you celebrating Earth Day? Planting trees? Recycling party? Picking up trash on the side of the street? How about with food that's delicious and sustainable? Many people don't realize it, but of all the choices they make on a daily basis, the one that perhaps has the largest impact on the planet starts on their plates.
Animal agriculture is at the core of our current environmental crisis. Over 50 percent of the world's arable land resources are dedicated to grazing livestock or growing their feed. In addition, this destructive industry uses a majority of our freshwater supplies, all while driving deforestation and emitting an enormous amount of air and water pollution. The UN estimates that animal agriculture is responsible for around 14.5 percent of global greenhouse gas emissions, while the Worldwatch Institute estimates it could be as high as 51 percent. And in spite of all this, 850 million people still suffer from food scarcity. The fact is, our food system is broken.
This all might seem incredibly daunting, but the good news is all it takes to reduce this massive impact is some delicious plant-based food. Yes, delicious food can save the world.
Since One Green Planet is the site with the largest vegan recipe database, eating for the planet has never been easier or more delicious. We have recipes for every food you could ever want, from macaroni and cheese to meaty burgers, and pizzas that you thought existed only in your dreams.
We have only one planet, so this Earth Day, try one of these 10 recipes that are both sustainable and delicious.
Jackfruit is a giant tropical fruit that's a relative of mulberries. It's still relatively new to us, but in East Asia, it's been around for several years as a substitute for meat in dishes due to its meaty, pull-apart texture. The jackfruit in this Barbecue Jackfruit Bowl is served on a bed of rice, with tender, cooked broccoli and a crunchy peanut cabbage slaw. The coleslaw sauce is packed with an infusion of peanuts, lime juice, soy sauce, sesame oil, and five-spice for a beautiful balance of flavors that are complementary to the jackfruit. The meaty jackfruit has a slightly chewy, yet tender texture, like pulled pork.
Forget beef and get ready for warmer weather with these hearty Beet and Black Bean Burgers! Beets give them their gorgeous pink color and earthy flavor while freshly cooked black beans add a meaty texture. Serve these topped with sprouts, fried onion, and mushrooms with sweet potato fries on the side.
Typically, fajitas refers to any kind of grilled meat in Tex-Mex cuisine. But, you know what they say — it's all about the seasoning and we can recreate the flavors we've come to love with plant-based foods. In these Easy Smoked Tofu Fajitas, tofu is covered in the marinated in a savory sauce and baked until crisp on the outside. Once the onions and peppers are chopped and ready, the whole dish comes together in one fell swoop. This colorful dish is crunchy, fresh, and smokey tasting. Plus, if the weather is nice, all the components can be grilled outside!
You better believe that cheese isn't off the table when you cut dairy out of your life. We can make cheese from nuts and seeds, or we can make cheese sauces from beans and vegetables. If you're looking for something decadent to snack on, then this recipe for Baked Herb-Crusted Cashew-Almond Cheese is top notch. Lemon juice combined with nutritional yeast give it a tangy, "authentic" flavor that's just begging to be served with sweet, fruity flavors. You can even alternate what flavors you serve this cashew-almond cheese with, so experiment to your heart's delight! The base of this cheese would also pair beautifully with dried cranberries, figs, and sun-dried tomatoes.
If you're looking for an effortless meal that doesn't disappoint, then you have to make this Lentil Veggie Loaf. What makes this meaty dish so wonderful is not only its heartiness but also its versatility. You can pack it with whatever vegetables you want and still achieve something delicious. It's topped with a spicy homemade barbecue sauce for extra flavor.
You won't even miss seafood when you make these Fish-Style Parsnip Fillets! Parsnip and fish may not have much in common, but it's what you do with seasoning that counts. Lemon pepper, bread crumbs, oil, remoulade, lemon juice, and dill is what takes this humble vegetable to the next level.
Garlicky cauliflower is smothered in tangy Romesco tomato sauce and topped with a dollop of creamy cole slaw in these Cauliflower Steak Sandwiches. To say that they're hearty and flavorful would be an understatement. We guarantee you'll have one of those moments where you're so satisfied and full, but are dying to go back in time just so you can relive eating this sandwich. Try it and you'll see this is not a dramatization.
These silky, Creamy Chocolate Turtle Squares are the perfect balance of refreshing matcha and sweet, creamy chocolate. Chickpeas give these treats their soft texture, while the dates provide their rich flavor. Enjoy these with a cold glass of almond milk.
If there's one device that people hardly regret buying it's an ice cream maker. Once you've entered an era of being able to know exactly what's in your ice cream, down to the last ingredient, it's hard to go back to store-bought pints. This Roasted Strawberry Ice Cream has a coconut milk base and is creamy, sweet, and studded with flavorful strawberries. Enjoy it on your favorite pie with a dollop of coconut whipped cream.
Inspired by the famous dessert from the Ottoman Empire, this smooth, creamy Raw Baklava Cheesecake sits on a crunchy, cinnamon-spiced crust. The best part about this cake is that, even though it's one of the most impressive things you'll ever taste or see, it's incredibly easy to make. You need only use your food processor twice — once for the crust and again for the base.
How are you celebrating Earth Day? Tell us in the comments!


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Q: Sync SharePoint 2010 UPS to a csv file I get a nightly update of all users' profile properties via csv.  I would like to setup the User Profile Service App to sync to that CSV.  I assume this shouldn't be terribly difficult and has likely been done before.  However my Google-Fu is not up to snuff and I cannot find any good examples.  I have found some examples using PowerShell but I thought that using BCS and sync might be a better idea.  Could someone please help me find an example of doing this in C#?

A: Personally, I would use PowerShell. But, if you really must use BCS, look at the samples for creating a custom BSC Connector to XML, XLS, or CSV. There are several out there. Scot Hillier wrote the book and there are samples in there: http://www.amazon.com/Professional-Business-Connectivity-Services-SharePoint/dp/047061790X
Once you have the BCS connection working you then create a secondary sync connection in the UPA for your BCS import and identify the key, like email or username.
Note, you will still need an LDAP source for initially creating users.

redpajama_set_name: RedPajamaStackExchange


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A meteoroid struck the surface of the moon recently, causing an explosion that was visible on Earth without the aid of a telescope, NASA reported Friday. But don't be alarmed if you didn't see it; it only lasted about a second. "It exploded in a flash nearly 10 times as bright as anything we've ever seen before," said Bill Cooke, of NASA's Meteoroid Environment Office."It jumped right out at me, it was so bright," said Ron Suggs of the Marshall Space Flight Center. It glowed like a 4th magnitude star, NASA says, thanks to an explosion equivalent to 5 tons of TNT.
Cooke reports don't be alarmed by explosion because you can't blow up the moon..
This entry was posted on May 20, 2013 at 7:49 am and is filed under Uncategorized.	You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.


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Bunn Gets Royle Backing
Former Oldham Athletic manager Joe Royle believes Frankie Bunn will be the perfect fit for the club.
Royle who oversaw Oldham between 1982-1994 has full confidence that Bunn is the right man for the job.
"I know he's a top-class coach and I've seen him work. He's got great recommendations from both Manchester City and Coventry City," he says.
"He's tried for the job before, he's always loved the club so all in all, it seemed a logical choice to me."
Royle also believes that his former players Bunn and assistant Andy Rhodes, from the famous 1989/90 season, will be a perfect match on the touchline.
"I think it's a good pairing with Andy Rhodes," he commented.
"You know, with Frankie as manager and Andy as his assistant, I think they'll really work well together."
Royle puts this down to the close relationship the pair both had on and off the pitch in their playing days.
"They were always very close, and their wives are very close too," he explained.
"It was a very close team to be honest with you.
"They had a fantastic comradery and Frankie and Andy both had a major part in that."
He also says that Bunn deserves the backing of the players and the fans ahead of the upcoming season.
"When I got the job at 33, people were saying we needed somebody with more experience. But positive results will alter people's minds; give him a chance."
The Latics legend believes the current crop of players Bunn has at his disposal could be enough to see the club go back into League One.
"I think they've got a great chance, they've still got the base of the squad," he said.
"They've got one or two players that have done well in a higher division, and that's always a good sign.
"So that, with a mix of youth, new and fresh players coming in, I expect them to do well."
However, he is wise enough to know that bouncing back from a relegation may take time to adjust to.
"It's always hard that first month after relegation, but once they get going, I expect them to get their whereabouts."
Don't miss Frankie Bunn's first league game as manager at Boundary Park when Oldham host MK Dons.
Tickets are avalable from the ticket office or online, for full details click here.
Joe Royle

redpajama_set_name: RedPajamaCommonCrawl


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"The U.S. government has stood idly by for far too long," Babin said in an interview with The Epoch Times. "This is one of the worst practices. It harkens back to the Nazi era in the 30s and 40s."
The first legislation to combat China's state-sanctioned practice of forced organ harvesting that targets religious and ethnic minorities was introduced in early March by a bipartisan group of U.S. lawmakers in the House and the Senate.
If approved, the Stop Forced Organ Harvesting Act would hold the CCP accountable for "these inhumane atrocities," according to Babin, who has co-sponsored the House bill (H.R.1592). Similar legislation was introduced in the previous session of Congress in December last year.
While there have been a number of congressional hearings and resolutions condemning forced organ harvesting, there's no U.S. law that addresses China's forced organ harvesting.
According to Babin, the international community has remained silent on this issue despite the vast amount of evidence of this practice. This is mainly because the CCP is the "bully on the block," pressuring other governments both economically and militarily.
"I think also here in the United States, we've seen people that may have either inadvertently or on purpose—because of profits, because of political pressure—looked the other way. And it's time to stop doing that," he said. It's reminiscent of how people looked the other way in the 1930s, he noted.
If enacted, the bill would authorize the U.S. government to identify, expose, and sanction individuals and government officials responsible for human trafficking or organ harvesting across the world.
The bill also mandates an annual report by the U.S. State Department on human organ trafficking in foreign countries. The report would introduce a tiered ranking system for determining which countries have the lowest (tier one), intermediate (tier two), and the highest (tier three) levels of organ harvesting and trafficking. This reporting system would shed light on governments that are directly or indirectly involved in the crime.
Following the final judgment issued in June last year by the China Tribunal, an independent people's tribunal based in London, the issue of organ harvesting in China has gained prominence.
The tribunal found that the killing of detainees in China for their organs has continued since allegations of forced organ harvesting for transplant surgery first surfaced in 2006. The tribunal concluded that the practice has been taking place "on a significant scale," with adherents of Falun Gong, a spiritual discipline that's also known as Falun Dafa, being the "principal source" of human organs.
Even after the tribunal's judgment, more evidence of organ transplant crimes continues to emerge in China with investigative reports indicating that the number of organs harvested continues to rise and that organs are available on demand, with short waiting times.
If passed, the U.S. bill would end the silence on this issue, according to human rights experts. The U.S. government would be able to deny or revoke passports for people who engage in the illegal purchase of organs.
The bill would also mandate an annual report on collaboration between the U.S. medical institutions and foreign entities involved in forced organ harvesting. In addition, it would prohibit the export of transplant surgery devices to entities involved in this crime.
"The time to act is now. People are being murdered. And these atrocities will continue as long as we look the other way," Babin said.
Falun Gong is a peaceful practice based on the tenets of truthfulness, compassion, and forbearance. The CCP launched a brutal persecution campaign against this practice in 1999 due to its growing popularity and the large numbers of Chinese citizens practicing Falun Gong. Untold numbers of practitioners have been detained, imprisoned and even killed for their organs. Forced organ harvesting is probably the worst genocide in human history.
← Fearless Hong Kong reporter says that she will not give in to the Chinese Communist Party
From assault to assassination, China is the world's leader in transnational repression →
04.10.2021 Sandeep Comments Off on CCP Plans to Export Immoral Organ Trafficking Abroad, NGO Leader Warns
06.07.2021 Sandeep Comments Off on Illegally detained and tortured for her faith, a woman breaks silence from prison
31.05.2021 Sandeep Comments Off on US State Department reveals that religious persecution is worsening in China


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Pray to God for healing.
Please take time to pray for those who have come here in need..
For security reasons we save the IP address 52.200.130.163.
Linda has stage 3 cancer. Winning the battle with God's help after 3.5 years. Please pray He will remove the pain from her back that she is currently suffering. Thank you for your prayers.
Prayer for my husband John's procedure tomorrow. Prayer that everyone in the room will be focused on his well being, health and healing. Thank you God. And so it is. Amen!!
Plz pray DILIGENTLY (until the Holy Spirit releases you from the responsibility) that God grant these requests (QUICK)......... 1. He raise up 23 million intercessors to pray these into completion, 2. That Carolyn enjoys total love harmony & union w/ God & her husband & 3. That her husband close & FUND 6 mortgage loans by 3/29/19 & 30 more by the end of 2019. Thanks very much!
I desperately need your help from Prayer Chain in persistent prayer in healing and to reconnect we need to reconnect. Were torn apart in our teens by my Mom she would be devastated today knowing that she caused my misery and regret her action to the point she would be crying she would apologize but it would be too late she's my Mom I still love her regardless. My former boyfriend and I go way back we met in high school in the same class when I left we saw each other again we started going steady then later on down the road my Mom tore us apart there is so much more to this story. We still love each other to this day hoping Jesus understands that my former boyfriend is and always be THE LOVE OF MY LIFE PLEASE JESUS BRING US BACK WE BELONG TOGETHER he desperately needs prayers (persistent) for his healing from Multiple Sclerosis and Leukemia and us to reconnect. P.S. He always respected ME he deserved to have ALL OF ME but didn't happen that way I'm deeply hurt by this (the way it turned out) and always will. Thank you so very much to >>>"PRAYER CHAIN"<<<for taking this SPECIAL request and for understanding to JESUS! PLEASE, WOULD PRAYER CHAIN LIFT US UP TO JESUS FOR HIS HEALING FROM MULTIPLE SCLEROSIS and LEUKEMIA and for us to reconnect. WE NEED THAT MIRACLE!
Please pray for the rapid healing of my brother in law Ed's lungs and for the new medicine to work, so that he is eligible for a lung transplant or well enough that he does not need one. Please pray for a miracle. Physicians are only giving him a little over a week life expectancy if the medicine does not work.
My cousin's husband has a mass in his lung. Please pray that it is benign or that it is treatable. ln Jesus' name l pray! Amen.
SUPERNATURAL BREAKTHROUGH Prayer Request/Prayer Request Please pray for my mom and I we have been gang stalked and harassed for the past few years. We need a SUPERNATURAL BREAKTHROUGH. The evil that has been done to us is indescribable. We need God to step in to reveal and expose the evil things that have been done to my mom and I. We need God ordained authorities to help us. We need for this to stop immediately. This is very crucial. Things are just out of hand. We need immediate help. We have done NOTHING wrong. We've always minded our own business. The devil has been busy with his demonic activities against us and our family. We've been patiently waiting on God to stop this. Please pray that this is stopped and that God pays us back double for our trouble and that the devil pays us back 7 fold for what he brought against us. Thank You!
Thank you lord for your mercy,goodness upon us &our kids. Praying for Gods encouragement, health, strength, protection, and Favor for our son ai. Praying he will live in alignment with Gods Will and Gods Way for his life moving forward in a positive manner. Praying for a healthy mind, body, spirit and soul. Praying he is surrounded and encouraged by Godly mentors and friends. Praying for new opened doors of opportunity (job, home, transportation needs, finances, relationships) for his success in 2019 in All areas of his life. Claiming Victory in Jesus name .Amen.
Prayer for Melva - prayer for absolute heath and healing. Prayer that she will invite God's healing power to touch her body and mind. Prayer for job prosperity for both Be and John. Thank you God for your blessings to come. And so it is. Amen!
My wife has been having several physical symptoms but not sure why or what is causing them. Please pray for answers and the right consultants. Also, please pray for total healing, emotional resilience, peace and encouragement as my wife feels helpless. She also has an eating disorder and all of her health issues are making this worse and she needs God's help to get her eating on track and do her exercises. She needs wisdom, strength and encouragement for all of this. Thank you.
Please pray for my sister to stop verbally disrespecting and verbally bullying our mother. She does not seem to realize the harm she is doing. Please pray for us to have some relief from this toxic home environment.
My friend is struggling with addiction. Pray for Christ to win. May he and his friends as well as every other soul in darkness discover their inner light of divinity and turn to live in the light. My prayers are for the healing of every person and animal on the planet. May God's love be felt from within and radiate out, guiding each to divine choices that lead to healing and wholeness. Blessings to you!
please pray for my husbands stress level and chest pains to decrease and for him to seek the Lord when he is feeling anxious or worried and not listen to the lies of the enemy. Also, healing for Kristi's body too and comfort for those who have lost loved ones.
Please pray for relationship with mother and adult daughter healing of pain and deeper relationship with Lord.
Hi, I would like you to ask for Jesus to heal me of spinal fluid leak and to heal my brain of the problems, please ask him to help me leave satanism. I have been involved for a long time because I was born into a family of it. Please ask him to defend my life at all times. Please ask him to enter me to help me change and repent and to guide me away from deception. Thank you. One last thing to ask, please ask Jesus to enter me to open my mind up to new possibilities and to help me dedicate my life to God. God bless you.
Have a problem starting back in 2017 I was attacked by a witch. It put me in the ICU and I was angel of the lord that gave me that revelation. I recovered and came home 2 nights later my 4 pound dog broke a lead for a 40 pound dog and I dislocated and broke my leg stopping him from getting hurt. Unfortunately I had extensive surgery on my leg, my ankle healed but the bone beneath my knee did not and now 6 type 23 titanium alloy screw that can hold over a 450 pounds each shattered and my knee looks like an antipersonnel mine t went off inside my knee. I have surgery coming up soon and was just informed that the same demon is claiming credit for my leg not healing and the screw (all 6 shattering) So my surgery dig the screw bits out, recut my leg, pack with bioadhesive and stem cells. and finally put in an external fixator Ilizharov cage for 6-8 weeks. Well I was just informed they will attack me while under anesthesia. So I am looking for prayers I do not know my exact date except my doc has a hard schedule and sahe is rearranging everything to make time for me in the next 2 weeks. Worried I will die on the table so I am asking for help.
I have a group of friends who do not know Jesus, I really want them to be able to go to heaven. Please pray that God would grant them his salvation and have mercy on their souls, and save them from Hell.
Please pray for my mom and I. We have been gang stalked & harassed. The evil that has been done to us is indescribable. We need God and God ordained authorities to help us! SUPERNATURAL BREAKTHROUGH!
Please pray for young Christian boy who is being accused of something he did not do however he could be in serious legal trouble and could have devastating effect on the rest of his life please pray for deliverance clearing of all accusations for this young man.
Please pray for my husband and I to get back together and live as man and wife. Please remove all obstacles to rejoin us.
Please pray for my son, Alex, who is an alcoholic and relapsed and also for my daughter, Autumn, who is likely on drugs. This breaks my heart. Thank you.


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Akim Djaha (né le  à Bordeaux) est un footballeur international comorien évoluant au poste de défenseur latéral polyvalent pour le FC Martigues ainsi qu'avec la sélection des Comores. Il a aussi la nationalité française.

Biographie

Préformation
En 2011, il intègre le pôle espoirs de Talence, pour deux ans de préformation.

Carrière en club
Akim Djaha joue en équipe de jeunes au Angers SCO lorsqu'il intègre en 2016 le Trélissac FC en National 2. Il rejoint ensuite le Vannes OC en 2020, toujours en National 2. Le , il signe un contrat au FC Martigues.

Carrière internationale
Akim Djaha est appelé pour la première fois en sélection nationale comorienne pour le tour de qualification de la Coupe arabe de la FIFA 2021 contre la Palestine à Doha le . Il est titulaire lors de ce match où les Comoriens s'inclinent largement sur le score de 5 à 1, échouant donc à se qualifier pour la phase finale prévue à la fin de l'année.

Références

Liens externes

Footballeur international comorien
Footballeur français
Naissance en septembre 1998
Naissance à Bordeaux
Joueur du Trélissac FC
Joueur du Vannes Olympique Club

redpajama_set_name: RedPajamaWikipedia


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18 USC 48: Animal crushing Text contains those laws in effect on January 25, 2021
From Title 18-CRIMES AND CRIMINAL PROCEDUREPART I-CRIMESCHAPTER 3-ANIMALS, BIRDS, FISH, AND PLANTS
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§48. Animal crushing
(a) Offenses.-
(1) Crushing.-It shall be unlawful for any person to purposely engage in animal crushing in or affecting interstate or foreign commerce or within the special maritime and territorial jurisdiction of the United States.
(2) Creation of animal crush videos.-It shall be unlawful for any person to knowingly create an animal crush video, if-
(A) the person intends or has reason to know that the animal crush video will be distributed in, or using a means or facility of, interstate or foreign commerce; or
(B) the animal crush video is distributed in, or using a means or facility of, interstate or foreign commerce.
(3) Distribution of animal crush videos.-It shall be unlawful for any person to knowingly sell, market, advertise, exchange, or distribute an animal crush video in, or using a means or facility of, interstate or foreign commerce.
(b) Extraterritorial Application.-This section applies to the knowing sale, marketing, advertising, exchange, distribution, or creation of an animal crush video outside of the United States, if-
(1) the person engaging in such conduct intends or has reason to know that the animal crush video will be transported into the United States or its territories or possessions; or
(2) the animal crush video is transported into the United States or its territories or possessions.
(c) Penalties.-Whoever violates this section shall be fined under this title, imprisoned for not more than 7 years, or both.
(d) Exceptions.-
(1) In general.-This section does not apply with regard to any conduct, or a visual depiction of that conduct, that is-
(A) a customary and normal veterinary, agricultural husbandry, or other animal management practice;
(B) the slaughter of animals for food;
(C) hunting, trapping, fishing, a sporting activity not otherwise prohibited by Federal law, predator control, or pest control;
(D) medical or scientific research;
(E) necessary to protect the life or property of a person; or
(F) performed as part of euthanizing an animal.
(2) Good-faith distribution.-This section does not apply to the good-faith distribution of an animal crush video to-
(A) a law enforcement agency; or
(B) a third party for the sole purpose of analysis to determine if referral to a law enforcement agency is appropriate.
(3) Unintentional conduct.-This section does not apply to unintentional conduct that injures or kills an animal.
(4) Consistency with rfra.-This section shall be enforced in a manner that is consistent with section 3 of the Religious Freedom Restoration Act of 1993 (42 U.S.C. 2000bb–1).
(e) No Preemption.-Nothing in this section shall be construed to preempt the law of any State or local subdivision thereof to protect animals.
(f) Definitions.-In this section-
(1) the term "animal crushing" means actual conduct in which one or more living non-human mammals, birds, reptiles, or amphibians is purposely crushed, burned, drowned, suffocated, impaled, or otherwise subjected to serious bodily injury (as defined in section 1365 and including conduct that, if committed against a person and in the special maritime and territorial jurisdiction of the United States, would violate section 2241 or 2242);
(2) the term "animal crush video" means any photograph, motion-picture film, video or digital recording, or electronic image that-
(A) depicts animal crushing; and
(B) is obscene; and
(3) the term "euthanizing an animal" means the humane destruction of an animal accomplished by a method that-
(A) produces rapid unconsciousness and subsequent death without evidence of pain or distress; or
(B) uses anesthesia produced by an agent that causes painless loss of consciousness and subsequent death.
(Added Pub. L. 106–152, §1(a), Dec. 9, 1999, 113 Stat. 1732 ; amended Pub. L. 111–294, §3(a), Dec. 9, 2010, 124 Stat. 3178 ; Pub. L. 116–72, §2(a), Nov. 25, 2019, 133 Stat. 1151 .)
2019-Pub. L. 116–72 amended section generally. Prior to amendment, section related to animal crush videos.
2010-Pub. L. 111–294 amended section generally. Prior to amendment, section related to depiction of animal cruelty.
Statutory Notes and Related Subsidiaries
Pub. L. 111–294, §3(c), Dec. 9, 2010, 124 Stat. 3179 , provided that: "If any provision of section 48 of title 18, United States Code (as amended by this section), or the application of the provision to any person or circumstance, is held to be unconstitutional, the provision and the application of the provision to other persons or circumstances shall not be affected thereby."
Pub. L. 111–294, §2, Dec. 9, 2010, 124 Stat. 3177 , provided that: "The Congress finds the following:
"(1) The United States has a long history of prohibiting the interstate sale, marketing, advertising, exchange, and distribution of obscene material and speech that is integral to criminal conduct.
"(2) The Federal Government and the States have a compelling interest in preventing intentional acts of extreme animal cruelty.
"(3) Each of the several States and the District of Columbia criminalize intentional acts of extreme animal cruelty, such as the intentional crushing, burning, drowning, suffocating, or impaling of animals for no socially redeeming purpose.
"(4) There are certain extreme acts of animal cruelty that appeal to a specific sexual fetish. These acts of extreme animal cruelty are videotaped, and the resulting video tapes are commonly referred to as 'animal crush videos'.
"(5) The Supreme Court of the United States has long held that obscenity is an exception to speech protected under the First Amendment to the Constitution of the United States.
"(6) In the judgment of Congress, many animal crush videos are obscene in the sense that the depictions, taken as a whole-
"(A) appeal to the prurient interest in sex;
"(B) are patently offensive; and
"(C) lack serious literary, artistic, political, or scientific value.
"(7) Serious criminal acts of extreme animal cruelty are integral to the creation, sale, distribution, advertising, marketing, and exchange of animal crush videos.
"(8) The creation, sale, distribution, advertising, marketing, and exchange of animal crush videos is intrinsically related and integral to creating an incentive for, directly causing, and perpetuating demand for the serious acts of extreme animal cruelty the videos depict. The primary reason for those criminal acts is the creation, sale, distribution, advertising, marketing, and exchange of the animal crush video image.
"(9) The serious acts of extreme animal cruelty necessary to make animal crush videos are committed in a clandestine manner that-
"(A) allows the perpetrators of such crimes to remain anonymous;
"(B) makes it extraordinarily difficult to establish the jurisdiction within which the underlying criminal acts of extreme animal cruelty occurred; and
"(C) often precludes proof that the criminal acts occurred within the statute of limitations.
"(10) Each of the difficulties described in paragraph (9) seriously frustrates and impedes the ability of State authorities to enforce the criminal statutes prohibiting such behavior."


text:
Miss Internacional 2016 fue la 56.ª edición del certamen Miss Internacional correspondiente al año 2016 cuya final se llevó a cabo el 27 de octubre de 2016 en la Sala municipal del Domo de Tokio en la ciudad homónima, capital de Japón. Candidatas de 69 naciones y territorios autónomos compiten por el título. Al final del evento, Edymar Martínez, Miss Internacional 2015 de Venezuela coronó a Kylie Verzosa de Filipinas como su sucesora.

Resultados

Reinas continentales

Premios especiales

Historia

Sede

La Organización Miss Internacional junto con el Kokusai Bunka Kyokai (Asociación Cultural Internacional, ACI) confirmaron en el mes de febrero de 2016 que la realización del Miss Internacional 2016 se llevaría a cabo el 27 de octubre del presente año, y que por cuarto año consecutivo, Tokio sería la ciudad sede de dicho certamen. También se aclaró que la noche final del certamen se llevará a cabo en la Sala municipal del Domo de Tokio ubicado en Bunkyō, Tokio.

Relevancia histórica de Miss Internacional 2016

Resultados
 Filipinas gana Miss Internacional por sexta vez, convirtiéndose en el segundo país que más ha ganado, después de Venezuela.
 Australia obtiene el puesto de Primera Finalista por tercera vez, la última vez fue en 1983.
 Indonesia obtiene el puesto de Segunda Finalista por segunda vez, la última vez fue en 1977.
 Nicaragua obtiene el puesto de Tercera Finalista por primera vez.
 Estados Unidos obtiene el puesto de Cuarta Finalista por sexta vez y por segundo año consecutivo en relación con el año anterior.
 Estados Unidos, Filipinas, México y Tailandia repiten clasificación a los cuartos de final.
 Filipinas clasifica por octavo año consecutivo a semifinales.
 Tailandia clasifica por cuarto año consecutivo.
 México clasifica por tercer año consecutivo.
 Estados Unidos clasifica por segundo año consecutivo.
 Argentina, Finlandia e Indonesia clasificaron por última vez en 2014.
 Japón y República Dominicana clasificaron por última vez en 2012.
 Rusia clasificó por última vez en 2011.
 Canadá clasificó por última vez en 2009.
 Polonia clasificó por última vez en 2008
 Nicaragua clasificó por última vez en 2002 e ingresa por primera vez, desde 1969, al cuadro de cinco finalistas.
 Australia clasificó por última vez en 1996.
 El Salvador clasificó por primera vez al cuadro de semifinalistas, apuntando a su vez su clasificación más alta hasta la fecha.
 Brasil rompe una racha de clasificaciones que mantenía desde 2011.
 De América entraron siete representantes a la ronda de cuartos de final, transformándose este en el continente con más semifinalistas; no obstante, solo Estados Unidos y Nicaragua llegaron a la final.
 Ninguna nación africana pasó a semifinales.

Otros datos significativos
 Regresa el formato de quince semifinalistas que fue usado por última vez en el año 2013.
 A partir de esta edición, la representante de Eslovaquia portó la banda bajo el nombre de República Eslovaca, lo mismo sucedió con la representante de China Taipéi, cuya banda figuró bajo el nombre de Taiwán.

Candidatas
69 candidatas compitieron en el certamen:

(En la tabla se utiliza su nombre completo, los sobrenombres van entrecomillados y los apellidos utilizados como nombre artístico, entre paréntesis; fuera de ella se utilizan sus nombres «artísticos» o simplificados)

 - Yoana del Carmen Don Marozzi
 - Tania Maria Nunes
 - Alexandra Britton
 - Caroline Sophie Julie Van Hoye
 - Polina Tsegalko
 - Katherine Añazgo Orozco
 - Manoella Alves Dos Santos
 - Amber Bernachi
 - Zhou Xinna
 - Yudy Daniela Herrera Avendaño
 - Min Jeong Kim
 - Raquel María Guevara Ávila
 - Dania Quesada Rivero
 - Sara Skals Danielsen
 - Ivanna Fiorella Abad Vásquez
 - Margarita Elizabeth Cader Medina
 - Anabel Delgado Torres
 - Kaitryana Leinbach
 - Kylie Fausto Verzosa
 - Emilia Seppänen
 - Khaoula Najine
 - Cindy Kofie
 - Joseanne Bear
 - Laura María Vadillo Urrutia
 Guadalupe - Presile Adolphe
 - Annalyn Soto Buan
 - Cassandre Joseph
 Hawái - Guinevere Davenport
 - Andrea Nicolle Salinas Godoy
 - Kelly Yeuk Lam Chan
 - Csillag Szabó
 - Rewati Chetri
 - Felicia Hwang
 - Katherine Gannon
 - Jyunna Yamagata

 - Stephanie Karam Tovar
 - Yesu Lin (Sulin Ip)
 - Olivia Constance Nicholas
 - Peachy Quitugua
 - Shavina Hulkua
 - María Geraldine Ponce Méndez
 - Alina Chirciu
 - Inngyin Htoo
 - Barsha Lekhi
 - Brianny Marcela Chamorro
 - Ivie Mary Young Akpude
 - Camilla Ellinor De Souza Devik
 - Jessica «Jess» Tyson
 - Melissa María Gesina Scherpen
 - Daniela Ochoa Barragán
 - Danea Juanita Panta Vargas
 - Magdalena Bieńkowska
 - Carina Marques Frazão
 - Gabriela Berríos Pagán
 - Romy Odile Simpkins
 - Cynthia María Núñez
 - Michaela Meňkyová
 - Alisa Manenok
 - Maseray Zelda «Trina» Swarray
 - Wang Huiqi
 - Ayesha Fernando
 - Tharina Botes
 - Maria Taipaleenmäki
 - Pattiya Pongthai
 Taiwán - Ai-Ning Tan
 - Hiba Telmoudi
 - Viktoria Kiose
 - Jessica María Duarte Volweider
 - Phạm Ngọc Phương Linh

Designaciones
 Yoana Don (Argentina) fue designada por la directora de la organización de Miss Mundo Argentina, Nadia Cerri, para representar a su país en este concurso tras haber sido la ganadora del certamen nacional de 2014.
 Raquel Guevara (Costa Rica) fue designada por los directores de la franquicia Reinas de Costa Rica, tras una larga trayectoria en concursos de belleza.
 Khaoula Najine (Francia) fue invitada por la organización Miss Internacional para ser partícipe en este certamen; tras la no renovación de la licencia a la organización Miss Francia encabezado por Sylvie Tellier, lo que le impidió seguir enviando delegadas francesas a dicho certamen.
 Laura Vadillo (Guatemala) fue designada por la organización Eventos S.A. encargada de producir el evento en ese país.
 Sulin Ip (Macao) fue designada por la directiva del la franquicia local para representar a su nación.
 Alina Chirciu (Moldavia) fue designada por la organización Miss Moldova, tras terminar como primera finalista en el certamen nacional.
 Geraldine Ponce (México) fue designada por la directora de la organización Nuestra Belleza México, Lupita Jones, para representar a su país en este concurso, tras haber quedado en tercer lugar en Nuestra Belleza México 2015.
 Gabriela Berríos (Puerto Rico) fue designada por Diana Montero y Desireé del Río, quienes son las directoras de la nueva franquicia tenedora de dicho país, tras una larga trayectoria en concursos de belleza.

Suplencias
 Bianka Fuentes (Ecuador) renunció al título nacional tras llegar a un acuerdo con la directiva de la organización Miss Ecuador tras no poder cumplir con sus deberes como reina titular, por lo que su suplente fue Ivanna Abad, quien se posicionó como segunda finalista en el certamen nacional en Miss Ecuador 2016.
 Alexandra Guzmán (El Salvador) no participó en el certamen pese a ser la reina titular de su país por razones desconocidas, por lo que Elizabeth Cader tomó su lugar en el concurso.
 Federica Ferro (España) fue destituida del título nacional por razones desconocidas, perdiendo así el derecho de concursar en este certamen; su suplente fue Anabel Delgado quien terminó como primera finalista en el certamen nacional.
 Anawate Georgette Adeyiga (Ghana) no participó a pesar de ser electa como reina titular en su país por razones no reveladas, Cindy Kofie tomó su lugar para que su país debute en este certamen.
 Manjusha Faugoo (Mauricio) fue despojada del título nacional, por incumplimiento de contrato como reina titular, argumentando diferencias con los directores de la organización nacional, dicha organización designó a Shavina Hulkua como su suplente para este certamen.
 Perla Núñez (República Dominicana) renunció al título tras encontrarse en estado de gestación, la organización designó a Cynthia Núñez como su suplente.
 Clara Långsjö (Suecia) fue despojada de su título por razones desconocidas, por lo que la organización de dicho país designó a Maria Taipaleenmäki como su suplente.

Abandonos
 Katia Dos Santos (Luxemburgo) fue retirada de la nómina oficial de las participantes, pese a haber estado en algún momento confirmada por razones no reveladas.
 A pesar de ser seleccionada para este certamen, Tatiana Rolín (Paraguay) no fue partícipe en esta edición debido al poco tiempo de preparación para dicha delegada.
 Çağla Çukurova (Turquía) renunció al título voluntariamente por decisión personal pese a haber ganado el derecho de representar a su país al día siguiente de ser coronada, por lo tanto no participó en este certamen, Çukurova no tuvo suplente por lo que su nación se ausentó en el concurso.
 Pese a haber estado confirmadas en algún momento Devontae Pinder (Bahamas) y Sandra Saeed (Egipto) no participaron en el certamen por razones desconocidas.

Datos acerca de las delegadas
Algunas de las delegadas del Miss Internacional 2016 han participado, o participarán, en otros certámenes internacionales de importancia:
 Cynthia Núñez (República Dominicana) fue finalista en Elite Model Look 2007 y participó sin éxito en Miss Mundo 2015.
 Jess Tyson (Nueva Zelanda) ganó el Miss Teen South Pacific 2008 y Miss Teen World Supermodel 2008.
 Gabriela Berríos (Puerto Rico) ganó Miss Turismo Intercontinental 2010, fue semifinalista en Miss Supranacional 2012 y participó sin éxito en Miss Universo 2014.
 Stephanie Karam (Líbano) fue candidata a Nuestra Belleza México 2016 y a Miss Líbano Universo 2018. Participará en Miss Grand Internacional 2019 representando al Líbano.
 Ivanna Abad (Ecuador) concursó sin éxito en Miss Panamerican Internacional 2012 y en Miss Yacht International Model 2012.
 Jessica Duarte (Venezuela) fue finalista en Look CyZone 2012.
 Hiba Telmoudi (Túnez) concursó sin éxito en Miss Mundo 2013.
 Tania Nunes (Aruba) compitió sin éxito en Miss Teen Continental 2014, y participará en Miss Tierra 2017.
 Yoana Don (Argentina) participó sin éxito en Miss Mundo 2014, fue segunda finalista en Reina Hispanoamericana 2015 y participará en Miss Grand Internacional 2017.
 Raquel Guevara (Costa Rica) compitió en Miss Intercontinental 2014, Miss Costa Maya Internacional 2014 y Miss Piel Dorada Internacional 2014, en ambas sin figurar; y fue semifinalista en Miss Panamerican 2015.
 Caroline Van Hoye (Bélgica) concursó sin éxito en Miss Europe World 2015 y en Miss Tourism Queen Internacional 2015.
 Andrea Salinas (Honduras) compitió sin éxito en Reina Mundial del Banano 2015 y en Miss Teen Universo 2015.
 Melissa Scherpen (Países Bajos) compitió sin éxito en Miss Tourism World 2015 y Miss Tourism Queen Of The Year Internacional 2015.
 Alisa Manenok (Rusia) concursó sin éxito en Top Model of the World 2015 y fue primera finalista en Supermodel International 2016.
 Maria Taipaleenmäki (Suecia) compitió sin éxito en Miss Tierra 2015.
 Elizabeth Cader (El Salvador) fue semifinalista en Top Model of the World 2016.
 Rewati Chetri (India) compitió sin éxito en World Miss University 2016.
 Amber Bernachi (Canadá) ganó el certamen Miss Eco Internacional 2017.
 Magdalena Bienkowska (Polonia) participará en Miss Mundo 2017, y en Miss Supranacional 2017.
Algunas de las delegadas nacieron o viven en otro país al que representarán, o bien, tienen un origen étnico distinto:
 Yoana Don (Argentina) tiene ascendencia italiana.
 Min Jeong Kim (Corea del Sur), Dania Quesada (Cuba) y Gabriela Berríos (Puerto Rico) radican en Estados Unidos.
 Ivanna Abad (Ecuador) radica en Australia.
 Laura Vadillo (Guatemala) radica en España.
 Stephanie Karam (Líbano) nació y radica en México, y tiene ascendencia mexicana por el lado materno.
 Camilla De Souza (Noruega) tiene ascendencia portuguesa.
 Daniela Ochoa (Panamá) tiene ascendencia colombiana por el lado paterno.
 Carina Frazão (Portugal) nació y radica en Sudáfrica.
 Maseray Swarray (Sierra Leona) nació en Estados Unidos.
 Tharina Botes (Sudáfrica) tiene ascendencia tailandesa.
 Maria Taipaleenmäki (Suecia) tiene ascendencia finlandesa de parte de ambos padres.
 Jessica Duarte (Venezuela) tiene ascendencia portuguesa-árabe y alemana.
Otros datos significativos de algunas delegadas:
 La candidata más alta fue Alisa Manenok (Rusia) con , mientras que la candidata más baja fue Cindy Kofie (Ghana) con  de estatura.
 Caroline Van Hoye (Bélgica) es modelo, actriz y una reconocida figura de televisión en su país, participó en un reality show llamado Vacances des Anges.
 Laura Vadillo (Guatemala) es hija de Julieta Urrutia, quien se posicionó como primera princesa en Reinado Internacional del Café 1982, ganó el certamen Miss Guatemala 1984, fue semifinalista en Miss Universo 1984 y meses después ganó el Miss Internacional 1984.
 Brianny Chamorro (Nicaragua) es practicante de taekwondo.
 Danea Panta (Perú) es modelo y presentadora de televisión en su país. Además, fue ganadora de la primera temporada del programa televisivo Peru's Next Top Model.
 Alisa Manenok (Rusia) es voleibolista profesional.

Sobre los países en Miss Internacional 2016

Naciones que debutaron en la competencia
 Ghana y Sierra Leona compitieron por primera vez en el certamen.

Naciones ausentes
(Esta lista es en relación a la edición anterior)
 Italia, Kenia, Luxemburgo, Mongolia, Paraguay, Rumania, Turquía y Zambia no participaron en esta edición.

Naciones que regresaron en la competencia
 Irlanda que compitió por última vez en 1994.
 Nigeria que compitió por última vez en 2011.
 Sudáfrica que compitió por última vez en 2013.
 Guatemala y Suecia que compitieron por última vez en 2014.

Referencias

Enlaces externos
Página oficial (en inglés)
 (en inglés)
 (en inglés)
 (en inglés)

2016
Concursos de belleza en 2016
Japón en 2016


text:
Q: How to init asking admin's pattern in my code? I'm developing app for Zebra device model MC33.
I like how internal apps ask to enter admin pattern (password) when I open Settings or others. In my app I have settings activity and I would like to ask user for authorization.
What I want to have is:
https://imgur.com/gallery/BwpAAPI
I used class DevicePolicyManager and then call for lock screen. (code is below)
But it turn off the sceen completely (it become black) like the device is switch off. Then I can enter pattern to turn it on.
This is screenshot what I get after using DevicePolicyManager:
https://imgur.com/gallery/TnHgDgs
DevicePolicyManager policy = (DevicePolicyManager)
 getSystemService(Context.DEVICE_POLICY_SERVICE);
policy.lockNow();

Such behaviour may be misleading. Do you have idea how to call for proper screen in my app?


Designing QC for a single test can be a challenge. Imagine the task of selecting the appropriate QC for more than 70 tests on multiple instruments across multiple laboratories. In this essay, Nuthar Jassam and colleagues describe how this was actually done at a network of laboratories in the UK.
In most clinical laboratories, quality control is used to monitor the level of quality that is being achieved, rather than controlling a planned and defined level of quality. In several publications Westgard has presented the concept of a scientific based quality control design that optimises the error detection and minimises false rejection for an analytical process[1,2]. In order to plan appropriate control rules for an analytical process, a clear definition of the quality goal is a fundamental necessity. This should be followed by the determination of the performance characteristics (imprecision and bias) for those tests for which quality control procedures are being developed and the number of control materials to run for each test (N).
The process of IQC rule derivation starts with calculating the process capability of detecting critical random error (ΔREc) and systematic random error (ΔSEc) and makes use of operating specification charts (OPSpecs), power function graphs and method evaluation decision charts (MEDx) to define the rules that provide the highest probability of error detection (Ped) and the lowest probability of false rejection (Pfr). The process capability is also given in terms of sigma metric and defines the number of control measurements (N) for each rule or set of rules. The process capability is a term that describes the tolerance of specification to imprecision and bias within the analytical process. High capability means that the process will likely produce a result within the tolerance specification. Low capability means that the process will likely produce a result outside the tolerance specification. Westgard defines that the right quality control procedure is one that has at least 90% probability of detecting a medically important error and less than 5% probability of false rejection. Simple control rules are preferred over multirule combinations, along with the lowest number of control measurements (N) that will provide the optimal error detection .
The IQC design approach should ideally be derived for each individual test in a multi-test system . In the USA, Westgard QC rules have been widely implemented due to the introduction of the Clinical Laboratory Improvement Amendments (CLIA) regulations which base their limits on the concept of total error (TE). However, in the UK Westgard control rules are not normally used appropriately. This is probably due to the apparent complexity of the rules deriving process, the lack of understanding of the potential benefits of this type of system or the lack of a CLIA counterpart regulatory body in the UK .
The perception of laboratory personnel has been that the biological variation model would be impractical in the setting of the quality specifications for clinical laboratories so this has limited the implementation of these types of quality specifications. We recently reviewed the quality system for our network and derived quality specifications based on the biological variation model . We compared our system performance characteristics in term of imprecision and bias against allowable imprecision and bias derived from the biological variation. This provided us with the first evidence of the practicality of this approach in a network of laboratories. We demonstrated that in a network of laboratories analytical variability between instruments of the same type does exist. Controlling variability requires a system that detects analytical error at the analytical stage. In this study we apply a well described scientific approach to control analytical variability within our network of laboratories. The concept was based on the application of analyte/analyser specific quality control rules (Westgard rules). The design of these rules takes into account the performance of a method and its quality analytical goal. The objective is to maximise the ability of our quality control process to detect the clinically relevant analytical error and control the across site analytical variability.
Analytical system: The analytical platforms consist of nine general chemistry analysers (Advia 1200, 1800, 1650 and 2400) and seven immunoassay analysers, all Centaur XP. These analysers were located on four geographically distant laboratories. All analysers were from a single manufacturer (Siemens Healthcare Solutions, Camberley, UK). All reagents (except 4 methods) were also from Siemens. The Internal Quality Control materials (IQC) were from Bio-Rad Laboratories, UK. The quality control procedure initially in use across all the network laboratories was 12s (Mean ± 2SD). Two control materials were measured per run (N=2). The frequencies for the IQC measurement for Advia were hourly and for the immunoassay were three times a day through the daily operation.
Quality specifications: The clinical requirements for quality were defined for all 71 tests measured in the core biochemistry laboratories. These tests include general blood and urine chemistries, endocrinology, therapeutic drug monitoring, tumour markers and cardiac troponin. The clinical requirements were defined at concentrations close to the clinical decision limit for each test and were given in terms of total allowable error (TEallowable), allowable imprecision (CVallowable) and allowable bias (Ballowable). The mechanism of the process for biological variation derived specification has been described .
Performance characteristics of current assays: Estimates of stable analytical imprecision (CVanalytical) were calculated for each of the 71 analytes from the average CV over a 6 month period and estimates of bias were calculated from EQA return data over the previous year. The mean bias over this time was calculated as a percentage difference of the method group mean. (BM = (result – method group mean)/method group mean * 100).
where TEallowable is the allowable total error requirement for the test in question, analytical imprecision and analytical bias are the estimates of stable observed CVA and BM for the test in question. The biological TEallowable, biological CVallowable and biological Ballowable were entered in the EZ Rules® 3 software package under biological total error mode. The TE value was entered under the analytical total error mode for all the analytes with other forms of quality specifications. The observed CVA and BM for each test and the clinical decision limit data for each test were also fed into the EZ Rules® 3 software. The optimal QC rules procedure that provides the best error detection and lowest false detection was selected automatically by the software. The probability of Ped and Pfr for the 12s rules for all studied tests was selected manually.
Quality specifications for our network were derived from three models; (1) the biological variation based model; the three levels model (TLM) (46 analytes), (2) the pharmacokinetic model as described by Fraser (9 therapeutic drugs) , (3) a mixed quality specification model based on expert opinion and external quality control specifications, which included 16 analytes. Three analytes did not fit with any form of specification due to poor performance. Figure 1 shows the distribution of the 71 studied analytes across the three types of quality specifications and it also shows the allocation of the 46 analytes with biological variation derived TE allowable to each level of the TLM model.
Figure 1: The source of quality specifications for the 71 analytes measured within the core biochemistry laboratories.
The pie chart shows the quality specification allocation for the analytes with TE derived from the TLM. The mixed category for analytes has the bias and CV limits selected from different levels in the TLM.
Fourteen analytes had TEallowable allocated to the minimal level. Seven out of fourteen were allocated to this level of performance due to unsatisfactory current analytical performance. The other seven were allocated to the minimal level because allocation to the desirable level wouldn't result in an improvement in quality. The 95% dispersion around the clinically relevant decision point showed that there was no significant difference between the desirable and the minimal CV levels (Table 1).
Table 1: Detailed performance of the 14 analytes that were allocated to the Minimal level of TE specification.
Analyte specific control rules were derived for 68/71 tests performed in the core biochemistry laboratories in the network. A total of 35/71 (50%) analytes were controlled by a single rule only. Thirty of these were for analytes with TE based on biological variation. The new rules were more relaxed than those originally used (12S) in the laboratories (32 analytes with 12.5S or 13S or 13.5S at N= 2 and 3 analytes with a 12.5S and N=4). These analytes were alkaline phosphatase (ALP), alanine transferase (ALT), amylase, gamma glutamyl transferase (GGT), creatine kinase (CK), C-reactive protein (CRP), cholesterol, HDL-cholesterol, creatinine, triglycerides, conjugated bilirbin, total bilirubin, lactate dehydrogenase (LDH), iron, lactate, uric acid, urea, Ca-19-9 and Ca-125, troponin (TnI), prostate specific antigen (PSA), salicylate and all tests for urine chemistry except urine albumin.
Eight out of 71 analytes had multi-rules 13S/22S/ R4S/ 41S at N=4, these were albumin, calcium, chloride, potassium, lithium, prolactin, thyroid anti-peroxidase (TPO) and thyroid stimulating hormone (TSH).
Maximum control rules 13S/22S/ R4S/ 41S / 8X at N=4 were required to control the performance of 11/71 analytes. These analytes were glucose, bicarbonate, magnesium, sodium, total protein, progesterone, testosterone, total triiodothyronine (TT3), total thyroxine (TT4), carbamazipne, and urine albumin.
14/71 analytes required different controls rules on different sites. These analytes were conjugated bilirubin, cholesterol, HDL-cholesterol, uric acid, α- feto protein (AFP), carcino-embryonic antigen (CEA), cortisol, luteinising hormone (LH), follicle stimulating hormone (FSH), human chorionic gonadotrophin (hCG), parathyroid hormone (PTH), paracetamol, theophylline, urine protein and urine uric acid. The requirement for different control rules was due to the difference in observed bias and imprecision across sites e.g. cholesterol; this analyte required 12.5S, N=2 on three sites and 13.5S, N=2 on one site. Serum uric acid required a single rule to control its performance on three sites and maximum rules 13S/22S/ R4S/ 41S /8X at N=4 on one site.
Three analytes had unacceptable performance and were impossible to control by any control rule; these were free thyroxine (fT4), digoxin and oestradiol.
Using the biological variation derived TE specifications, we found that 50% (23) analytes perform at a level of 5 sigma or higher, 20% (9) analytes performed at sigma varying between 4 and 5, 20% (9) analytes performed at 3-4 sigma and 10% (5 analytes) performed at sigma less than 3. Figure 2 gives the analytical performance of the biological variation based quality specification analytes in terms of sigma (σ).
Figure 2: The system capabilities given in sigma for the 46 analytes that have a quality specification based on biological variation.
The probability of false rejection was set to be maximally at 5% for the new rules selection. The 12s rule usually has a false rejection of 9%. Table 2 shows ped and pfr with the new rules and with the 12s rule for the general chemistry only.
Until recently we had used a simple Westgard rule system 12s (mean ± 2 SD) for controlling analysers on each site across our multi-site laboratory network. As described previously this was not satisfactory for the control of analysers across the network. Furthermore, this rule has Pfr of 9% at 2 control measurements . This high false rejection rate would render this rule a major waste of laboratory resources due to repeat analysis of controls, and patients' samples resulting in an increase in the cost of the analytical process and a waste of time and effort. If we considered the number of analytes measured and the volume of testing performed on a daily basis in our network of laboratories, which exceeds 20,000 tests per day, one would assume this could be a significant waste of the laboratory budget.
This type of waste can be avoided by designing a quality control procedure that is based on the quality goal required clinically and the performance characteristics of each test/analyser. Therefore, the laboratory's efforts would be focused on the analytes that require the maximum control. The ideal IQC design should be derived for each individual test in a multi-test system, selecting where possible the combination of the highest Ped and the lowest Pfr . In this study, the quality control rules were selected at the Pfr has been set at a maximum of 5%. This has resulted in a cumulative reduction in the Pfr by more than 50% (Table 2).
Table 2: The probability of error of detection (PED) and the probability of false rejection (PFR) of the new quality control rules in comparison to the OLD QC RULES (12s rule).
The ALP and total protein examples are highlighted. ALP: the QC rules selected for this analyte will give the probability of systematic error detection of 89% and random error detection of 61%. The false rejection for these rules is zero. The current rule 12s has higher error detection but almost one run in ten has a false error. For total protein, both the new rules and the current rule have poor error detection. However, the false rejection in the current rule is over 40% ( 9/21). This means that over 40 times out of 100 runs the analyser would have been stopped for a false error flag.
It was also found that 19 analytes required multi-rules or maximum rules to control the analytical process required to satisfy the quality goal. This shows that the initial 12s rule alone has not been efficient enough to control the performance of these analytes, hence the variability in analytical performance between sites. Furthermore, 14 analytes required different quality control rules on different sites, or on different instruments within the same site. As the same analyte has the same TE across all sites, the difference in the quality control rules required stems from a difference in the performance indicators of these analytes, which as described previously can be ascribed to varying levels of hardware deterioration of the instruments on different sites. This can be due to different workloads or an inherent difference in the design of those instruments.
The new quality control rules rely on a scientific approach, taking into account the quality goal and the observed performance of an analytical method. For example, if the analytical process is more precise than medically required (e.g. iron, TE= optimal, σ= 7.5) the quality control process can be relaxed and would only need one rule such as 13s to achieve the required quality goal. Controlling these analytes with 12s or multi-rules would have resulted in a waste of resources. However, assays with unsatisfactory performance (low system capability or low sigma) may require the maximum control rules to achieve the desired goal. Our data showed that for 50% of total analytes measured in the core biochemistry a more relaxed rule than the initial rule in use could be used. This shows that this control rule design provides a cost effective model because the decrease in the cost of controlling the analytes with more relaxed control rules is transferred to those tests that require a higher degree of control.
World class quality is generally recognised as a 6 sigma process (3.4 defects per million on the sigma short-term scale). The 3 sigma performance (66,807 defect per million on the short-term scale) represents the minimum standard and defines the region of unacceptable performance . In the clinical laboratories improving processes to achieve a performance above 5 sigma (233 defects per million on the sigma short-term scale) is of little advantage and can be costly. Performance at 4 sigma (6,210 defect per million on the sigma short-term scale) is considered satisfactory for the clinical laboratory if the process is adequately controlled . Using the biological variation based TE resulted in achieving performance of 4-6 sigma for 70% of the analytes. However, it is important to recognise that the size of critical error (systematic/random) or sigma index depends on the allowable TE and the performance of the measurement system. A smaller total error or poor CV and bias would result in a small sigma or critical error. Biological variation based quality specifications represent a narrow form of quality specifications, which means that we have to detect a smaller but clinically relevant change in the analytical process. In this case, achieving a smaller sigma but a narrower quality requirement is better . Our data showed that 30% of the studied analytes had a performance consistent with a poor sigma (σ ≤ 4), however, most of these analytes had a CV within the biological variation for all the sites. For example, glucose had an average analytical CV ≤ the allowable CV (2.9% (desirable level)) on all sites. Given that the TEallowable is 6.9%, a CV of 2.9% would result in performance of 2.4σ, whereas improving the analytical performance to achieve a CV of 1.4% (optimal CV), which meet 5σ performance remains a goal for this analyte.
On the other hand, for some analytes that were allocated to the minimal level due to current unsatisfactory performance, achieving 5 sigma would be challenging without an improvement in the method technology and formulation.
In our study, we presented a central quality system that enables the identification of poor performance in the analytical process in a retrospective manner . The system was based on quality specifications derived from biological variation data and software that enabled the application of common specifications and across laboratory analytical performance comparison. In this paper, we have added the last dimension to this system. This was based on deriving analyte specific quality control rules that maximise the detection of analytical error during the analytical stage, and helps to maintain a stable analytical performance.
The 'current' data field represents the worst imprecision over a 6 month period across all the analysers in the network.
The CVI values for glucose, 5.7% [12 ].
The effect of imprecision at the three performance levels around a glucose concentration of 7.0 mmol/L.
Glucose is reported to one digit after the decimal point through the whole range. Our current performance lies within the desirable level. However, the optimal level gave the least dispersion interval. A cut off of around 7.0 mmol/L glucose is used diagnostically, hence we believe that the optimal performance level is the ideal target to achieve clinical decision making.
Biological variation data for prolactin (PRL) is not available. TE was estimated on the basis of the tolerance around a clinically relevant cut off value and current performance. The cut off for PRL was selected as the upper limit for monomeric PRL reference range (438 mu/L) .
Allowable CV= 10% (based on an average of 6 months performance).
Allowable bias: 10% (The 75 quartile of the method group in NEQAS scheme).
Some quantities that are measured in clinical biochemistry do not exhibit biological variability such as drugs. For these analytes, Fraser et al. derived a formula to calculate the desirable analytical goal for precision based on the fundamental pharmacokinetics theory . Phenytoin is an anti-convulsant drug with a half life in chronic administration of between 6 and 24 hours. .
In premature babies, phenytoin has a long half life due to the immaturity of the liver. The longest half life was used to derive a quality specification for this analyte, because it can deliver the most stringent analytical goal. Therefore the desirable CV is 8.3%.
Method bias= 10% (estimated from the External Quality Assurance Scheme).
Westgard JO. A method evaluation decision chart (MEDx chart) for judging method performance. Clin Lab Sci 1995; 8: 277-283.
Westgard JO. Internal quality control: planning and implementation strategies. Ann Clin Biochem 2003; 40: 93-611.
Westgard QC, Inc,. EZ Rules ® 3 automatic selection of statistical control rules for laboratory tests. Madison, WI: Westgard QC. Inc,. 2005.
Housley D, Kearney E, English E, et al. Audit of internal quality control practice and processes in the south-east of England and suggested regional standards. Ann Clin Biochem 2008; 45: 135-139.
Fraser CG, Hyltoft Petersen P, Libeer JC, Ricos C. Proposal for setting generally applicable quality goals solely based on biology. Ann Clin Biochem 1997; 34: 8-12.
Fraser CG. Desirable standards of performance for therapeutic drug monitoring. Clin Chem 1987; 33: 387-389.
Westgard lesson. Six sigma quality management and Desirable laboratory precision. www.westgard.com/essay35.htm (accessed 2/12/2009).
Westgard JO. Six sigma quality design and control: desirable precision and requisite QC for laboratory measurement process. Madison, WI: Westgard QC, inc., 2001.
Westgard lesson. www.westgard.com/a-six-sigma-design-tool.htm (accessed 2/12/2009).
Campbell BG. Evaluation of two types of medically significant error limits and quality control procedures on a multichannel analyser. Arch Pathol Lab Med 1989; 113:834-7.
Ricós C, Alvarez V, Cava F, et al. Desirable quality specifications for total error, imprecision, and bias, derived from biological variation. www.westgard.com/biodatabase1.htm (accessed on 6/09/2009).
Jassam NF, Paterson A, Lippiatt C, Barth J. Macroprolactin on the adiva centaur: experience with 409 patients over a three-year period. Ann Clin Biochem 2009; 46:501-504.
Mike Hallworth and Ian Watson. Ed. Therapeutic drug monitoring and laboratory medicine. ACB Venture Publications 2008.


Amy sees patients at our Chaska and Minnetonka offices.
Married. One son and one daughter. Loves horseback riding, hunting, fishing, spending time at the lake, traveling and spending time with family and friends.


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Home/Sports/Corinthians official confirms that Vítor Pereira wants to stay at the club in 2023; check out
Corinthians official confirms that Vítor Pereira wants to stay at the club in 2023; check out
Admin September 17, 2022 Sports Leave a comment 12 Views
Roberto de Andrade, director of football at Corinthiansconfirmed this Friday that coach Vítor Pereira wants to stay at the club in 2023. The news was given first hand for the Sports Gazette.
Just like the Gazette found, the manager said that the choice to remain does not depend only on the coach. The only obstacle for VP to continue at Corinthians is his family.
"For his person, what he found here at Corinthians, that said by him, the affection received, the way we conduct the work with him, he is completely happy. He says he has never worked in a club where he was so well received. We realize that he wants it, but it's not in his hand either.. You have to talk to your wife, children, everything, to solve it. He also thinks he wants to, but he can't say either. It's a delicate issue, and we have to respect it," Roberto said in an interview with the podcast. Today Yes.
"He had a conversation with us and promised that he will resolve this as soon as possible, even to put the club at ease. We cannot wait for a decision at the end of the championship to chase after it, this is an atypical year. The championship ends in November, and we're going back in mid-December, starting pre-season for early January, so we've got to have everything set up," added the director.
After a reality check regarding the Brazilian calendar, short squad and lack of options on the bench, the coach got used to the club environment and even likes the pressure that Corinthians brings in his daily life.
In addition, the full support he receives from the top management, in addition to being heard in relation to some reinforcements, made him think about the continuity of the work. The clearest examples are those coming from Fausto Vera and Yuri Alberto.
The first was a nominal request from Vítor Pereira, and Alvinegro paid a large amount to be able to count on the former Argentinos Juniors midfielder. VP bankrolled the purchase and said it would bear future fruit for the club.
The center forward has the characteristics requested by the commander, especially age. He, by the way, is already corresponding: there are five goals and an assist in 14 games.
Vítor Pereira has a link with Corinthians only until the end of this season. The coach and his coaching staff have played 49 games, with 19 wins, 16 draws and 14 losses since his arrival at Timão, in February this year.
In a press conference, VP spoke on the subject, confirming that he intends to give the club an answer before the end of the season.
"Because of the respect I have for the fans and the club, I have to anticipate, I have to define my life and that will happen, for sure (before the end of the year). You have to have a conversation with the president, with the family, understand… Today (Thursday), if we lost… Football is not… There would be criticism. Football is like that, I'll try to find the timing right, but I will anticipate, out of respect for the club", assured the coach in press conference after the victory over Fluminenselast Thursday night.
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Of the many protest albums to surface in 2017, the recording debut of Irreversible Entanglements is what rises up and above the crowd. A quintet of vocalist Camae Ayewa (aka Moor Mother), alto saxophonist Keir Neuringer, trumpeter Aquiles Navarro, double bassist Luke Stewart and drummer Tcheser Holmes, they stand up to what's wrong, voice and instruments in unity and channeling a rage that won't be contained. In a year when it seemed so much went to hell and the flaws emerged all around us, Irreversible Entanglements is what it sounds like to fight back. And in a context outside of politics and society, this album isn't so easily carried through. Spoken word and free improvisation rarely see such a remarkable confluence as on this recording, where each word seems perfectly married to an instrumental phrase, where the changes of intensity of the former rise and fall with those of the latter, and where inflections and patterns and running narratives have a complementary relationship like they were fated to be together from the very start. Irreversible Entanglements has a specific perspective, a blunt point of view, and it resonates with a power that transcends its personal meaning and touches upon the protest against everything that's corrupt. This is the gold standard for protest albums.
Music from Philadelphia, NYC and Washington DC.
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Love this pick and really enjoying your list. Was there any label more compelling in terms of high impact for a small number of releases than International Anthem? Jaimie Branch, Irreversible Entanglements, Makaya McCraven and Hear In Now all had truly unique, "get under your skin", beyond-categorization releases this year and they were all great.
Int'l Anthem had an amazing 2017. And high impact is exactly the phrase I would use to describe it. The only other label that's been nearly as strong over the course of the last year is Jaeger Community Music… but taken as a whole, Int'l Anthem kicked out an electricity that is unparalleled in 2017.


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