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Hajdu–Cheney syndrome, also called acroosteolysis with osteoporosis and changes in skull and mandible, arthrodentoosteodysplasia and Cheney syndrome, is an extremely rare autosomal dominant congenital disorder of the connective tissue characterized by severe and excessive bone resorption leading to osteoporosis and a wide range of other possible symptoms. Mutations in the NOTCH2 gene, identified in 2011, cause HCS. HCS is so rare that only about 50 cases have been reported worldwide since the discovery of the syndrome in 1948

Signs and symptoms
Hajdu–Cheney syndrome causes many issues with an individual's connective tissues. Some general characteristics of an individual with Hajdu–Cheney syndrome include bone flexibility and deformities, short stature, delayed acquisition of speech and motor skills, dolichocephalic skull, Wormian bone, small maxilla, hypoplastic frontal sinuses, basilar impression, joint laxity, bulbous finger tips and severe osteoporosis. Wormian bone occurs when extra bones appear between cranial sutures. Fetuses with Hajdu–Cheney syndrome often will not be seen to unclench their hands on obstetrical ultrasound. They may also have low-set ears and their eyes may be farther apart than on a usual child, called hypertelorism. Children's heads can have some deformities in their shape and size (plagiocephaly). Early tooth loss and bone deformities, such as serpentine tibiae and fibulae, are also common in those affected.

Genetics

Hajdu–Cheney syndrome is a monogenic disorder. The disorder is inherited and controlled by a single pair of genes. A single copy of the mutant gene on an autosome causes HCS. HCS is an autosomal dominant disorder, only one parent with the defective gene is needed to pass the disorder to the offspring.

Mutations within the last coding exon of NOTCH2 that remove the PEST domain and escape the nonsense-mediated mRNA decay have been shown to be the main cause of Hajdu–Cheney syndrome. The NOTCH2 gene plays a very important role in skeletogenesis. Mutations of NOTCH2 that seem to cause HCS occur in the last coding exon of the gene (exon 34). These mutations remove PEST domains, which mediate proteosomal destruction of the protein. These PEST domains are removed due to the premature stop codon in the amino acid sequence. All HCS alleles are observed to have premature protein destruction before the PEST sequence is fully translated. The result is a mature NOTCH2 gene with a partially completed PEST sequence. In some cases, no PEST sequence at all is seen. This leads to the no proteosomal destruction of the protein.

The NOTCH2 gene is ubiquitously expressed in all embryonic tissue. When researching HCS in mice, the homozygous deletion of NOTCH2 leads to death. This observation is important because it explains how the HCS phenotype is not isolated to only one system of the body. NOTCH2 is also shown to regulate RANK-L osteoclastogenesis, which is the production of functional osteoclasts. Osteoclasts are the component that breaks bone down. This is why bone loss is observed in HCS patients, due to the overactivation of RANK-L.

Pathogenesis
The mechanism thought to cause HCS is an abnormality in osteoblast and osteoid function. These are major components of bone development, and the low function of each leads to the weak bones that characterize HCS.

Diagnosis
One of the main methods of pinpointing a NOTCH2 mutation that leads to HCS is through whole genome sequencing. This is then followed by exome capture by means of in-solution hybridization. The exome part of the genome consists of exons. Parallel sequencing follows the hybridization, which results in about 3.5 Gb of sequence data. These sequence data are then analyzed. Through sequence analysis and symptom presentation in HCS patients, this proves to be the most definitive method of diagnosis.

Types
Laboratory testing reveals multiple mutations of HCS. Two genetic variants result in sporadic HCS symptoms, which are HCS-02 and HCS-03. These mutations produce symptoms that come and go, but have been present de novo. HCS-03 was identified as the variant that is passed through affected family members and presents symptoms throughout the lifetime of the individual. All variants of HCS lead to the same premature termination of PEST sequences which compromise normal function of NOTCH2. NOTCH has four different receptors, which have an affinity for similar ligands. They are classified as single-pass transmembrane receptors.

Treatment
Since about 2002, some patients with this disorder have been offered drug therapy with bisphosphonates (a class of osteoporosis drugs) to treat problems with bone resorption associated with the bone breakdown and skeletal malformations that characterize this disorder. Brand names include Actonel (risedronate/alendronate), made by Merck Pharmaceuticals. Other drugs include Pamidronate, made by Novartis and Strontium Ranelate, made by Eli Lilly. However, for more progressive cases, surgery and bone grafting are necessary.

Eponym
It is named after Nicholas Hajdu (1908–1987), a Hungarian-English radiologist working in the UK and William D. Cheney, MD (1899–1985), a US radiologist.

References

Further reading

External links
  OMIM entry on Hajdu–Cheney syndrome
 Acroosteolysis dominant type at Orphanet

Autosomal dominant disorders
Congenital disorders
Rare syndromes


**UPDATE** Use the code BETTERPHOTOS for 50% off Kelly's photo course for yourself. Code expires October 31, 2017.
While I stay home with my kids full time, I do not normally find that there is much extra free time in my day. There is certainly more time to accomplish housekeeping tasks and grocery shopping (things I do with kids in tow), but the things I do that interest me the most always happen after bedtime.
I also believe that it's critically important to hang onto your hobbies and interests, especially when you have small kids. Everyone knows the benefits of self-care, and cultivating your interests is a great way of taking care of yourself.
I personally have a few key interests, and those who know me well will immediately think of knitting. I do knit, a lot. Especially this time of year, with Christmas approaching. But, like most people, I do not have singular tastes. I have always owned a DSLR camera because I've always loved to take photos, and I've been fortunate enough to be close with several people who are exceptional photographers, so have been able to learn through osmosis. Until recently, I didn't put much effort into really improving the quality of my photos, but on our recent family trip to Italy, I found myself dismayed that I wasn't able to capture the beauty of what I saw around me. I couldn't take a good photo of literally amazing and incredible views.
Around the same time, Kelly Lawson was running a promo on her online photo course, and from our AirBnb in the middle of Tuscany with weak wifi, I bought it on my cell phone. When I got home, I devoured the course and immediately started to practice my skills. I literally cannot believe the difference in my pictures. It's shocking. My equipment has never changed, but the quality of my photos has significantly.
This has had an interesting side effect, in that I now want to take pictures all the time. The camera comes with me everywhere. I can barely keep it charged, or my SD cards cleared out. I'm always looking for new subjects, so lucky for me when we had some good news in the family. My sister-in-law got engaged over the weekend, and I convinced her and her fiancee to let me take some shots of them. It's not hard to make happy people look happy, but it is a thrill and privilege to shoot subjects other than my kids.
Yesterday at 9:30am I could already tell that both boys needed a nap. Sam always naps, but it's not often that Charlie does anymore, so I was excited at the possibility of them napping together later in the day. Of course though, tired kids are often cranky kids, and right before lunch we had an epic meltdown situation, which doesn't happen too often, but does happen. While both boys were acting out and crying, I was calmly cutting up an apple in the kitchen, not quite ignoring them, but certainly not reacting to their bad behavior. And I was laughing to myself, because a year ago this would have sent me into a panic and I would have been freaking out right alongside them.
When we brought Sam home from the hospital, not a lot changed right away. Except for the overnight wakings/feedings, I think most people would agree that having a newborn is easier than a toddler. Since a newborn doesn't need much, our days still revolved around Charlie. We would spend the mornings out, the baby would sleep in his stroller or car seat, and then we would come home for lunch and Charlie would nap. I quickly learned though, how difficult it is to bring two kids out of the house on my own, and gradually, as Sam required more routine (especially for sleeping) learning to manage two kids became really really difficult.
I vividly remember this one time that shook me so much, I avoided leaving the house for weeks afterward. I took both kids to the playground at Rockwood when Sam was maybe 2 months old. There were several daycare groups at the playground at the time, so there were dozens of adults and kids running around everywhere. Charlie, being only two, climbed to the top of a slide structure only to get too scared to come down, while a lineup formed behind him. He couldn't maneuver to turn himself around and climb down, and he started to panic and cried for me. I watched helplessly as I tried to figure out if I was comfortable leaving my infant alone on the ground in the stroller with this many people at the playground in order to scale the structure to get him. I had a moment of intense anxiety and panic, and then I was rescued by the 5 year old daughter of a friend. She came out of nowhere and held Charlie's hand, helped him back down and then played with him until we left. My relief was so intense, I cried. If a playground could render me desperate and helpless, how would I ever be able to leave the house again comfortably with both of them? How could I keep them both safe? How could I give one of them what they needed without ignoring the needs of the other?
This was a really difficult adjustment, and I didn't handle it very well for awhile. If you are like me, when you are still trying to get the hang of something and you are low on sleep and adult interaction, you feel like a failure. I cried a lot. I drank a lot of coffee. But life goes on, and after awhile we did get back out there.
I guess maybe the moral of the story is that sometimes things are just hard. Even things you think you are prepared for. I'd already had a baby, so I thought I knew what I was in for, but I was surprised at how much there was to learn this time around. Just keep going, and feel comfort in the knowledge that it's not just you. I adjusted, tried some new things and ultimately figured it out, and now (I think) we are flourishing. Our days look different now, but it's been a process of figuring out what makes us comfortable and allows me control over them when needed to keep us all safe and happy.
Yesterday morning we got off to a rough start, but in the afternoon my kids napped together and I was super productive in a quiet house. I even drank a hot coffee. When they woke up refreshed and happy, the tantrums from the morning were a distant memory.


Our Stewarton surgery is an RCVS accredited Core Standards Practice, welcoming dogs, cats, birds, exotics, and small mammals.
All consultations during these times are pre-booked by appointment only. Outside of these times are for emergencies only. If you require either a routine or emergency appointment please call the surgery on 01560 485193.


Tarun Gupta July 20th, 2017 Social Media Marketing no comments.
Videos are awesome. They tend to engage more audience than any other digital medium we know. YouTube, the #1 video search engine is now marketers paradise.
On every alternate day, Google uncloaks new YouTube features to make the platform marketer's goldmine. Despite all that YouTube can offer, many marketers either haven't yet tested its worth, or failed to yield expected results for some reasons.
I am listing here 9 important YouTube video elements that you should rightly place while launching the video.
Your brand matters you the most. That is why you should never miss any opportunity to include it in your marketing. Since branding helps in building loyalty, adding info footage in YouTube videos helps viewers to immediately identify your brand. Moreover, branded footage helps audience remember the video and associated brand for longer.
At a point of time viewers forget your video and actual content, but they can recall your brand and refer it to others if they remember the name.
Adding an intro means telling your viewers why they should watch your video. Audience are impatient people. They leave the video midway if it's stale and dumb.
You can escape this embarrassment. Just add an attention-grabbing video intro to tell them what this video is all about.
Add an intense introduction of the video to explain why audience should watch the video, and how that will benefit them. A superb YouTube video introduction gives your audience a sense that you have solution for some of their raised problems. It builds trusts and inflicts loyalty.
An attention grabbing background music boosts the interest quotient. It grabs audience attention, sets their mood for the viewing session and create a better emotional connect.
The background music should not be distracting, else it could play spoilsport. A great soundtrack gives audience more reasons to stick to the video and share it with others.
A beautifully crafted video with stunning intro and nice background can go unnoticed if you're voice in the video is not audible. A video with cracking voice and pauses eventually fails to deliver the message.
If you have just used graphics to illustrate your points, then loud background is enough. On the other hand, if your video requires human voice for better presentation, make sure it can be heard without being affected by the background score.
Let's call it brevity. We don't undermine the might of short videos, neither we underplay longer one.
Content of the video mainly decides the length of the video. A phone review could last for 10-15 minutes, whereas, a issue-based short film may take time to finish off the message. Audience primarily bother about the intent of the video, message it carries and connect it creates.
A 2 minute YouTube video may grab million eyeballs, whereas, a 15 minute short film could fail to resonate. All that matter is the content and its engagement quotient.
Adding Call to Action means telling viewers what to do the next.
Every video has a message to deliver and to invite audience to take some action.
Most of the time viewers are asked to subscribe respective channels, like videos and write comments. Now, marketers are inviting audience to their social media pages and their service websites as well right from their YouTube videos.
You need to be creative about your selection of call-to-action. Most often they are used at the end of the videos, but in case of videos that are longer in duration, they shouldn't be placed at the end.
If videos are longer, consider using clickable annotations that may appear in the first 5-6 seconds of the video.
Want to add more YouTube Video Elements in the list, please comment and tell us about that.


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Iceland takes on M&S with new posh pizza range
Made in Italy, they're 70 per cent cheaper than Marks & Spencer's equivalent
Nisha Mal
Iceland is launching a new wood-fire posh pizza range to rival M&S's.
The frozen food specialist says its new offerings are 70 per cent cheaper than Marks' equivalent, which come in at £6.
Shoppers can choose from five toppings, including Margherita, Chicken, Mozzarella, Parmesan and Ricotta Cheese, Spicy Salami, Italian Sausage and Spicy Tomato Arrabbiata Sauce and Ham, Portobello Mushroom and Mascarpone Sauce.
Costing £1.75 each, Iceland's new pizzas are made in Italy, and have been lovingly hand-crafted in an area on the outskirts of Venice.
Iceland's Head Chef, Neil Nugent, said: "We wanted to bring high quality, authentic Italian-style pizzas to the UK, which have been adapted to suit British tastes, and we have sourced our ingredients from only the best suppliers just outside of Venice to ensure a genuine experience for our shoppers.
"All of the Ultra-Thin Wood Fired range is stone baked to perfection in wood fired ovens in Italy before making its way to Iceland stores."
Each base is made with dough that has been left to rest for 24 hours, to ensure it is full of flavour and will be light and crisp when baked.
It's then topped with rich tomato sauce, mozzarella shavings and a selection of delicious toppings.
According to Iceland, mozzarella shaving ensures a better distribution, resulting in more cheese per bit.
To finish, the pizzas are stone baked in wood fired ovens.
The new range will be available to buy in stores from February 18.
In keeping with the pizza theme, Iceland is reducing the price of Chicago Town offerings especially for National Pizza Day, which takes place tomorrow.
Shoppers can save £1 on classic cheese and pepperoni pizzas, down from £2.50 to £1.50.
Summer HolidaysThese three Lincoln parks have just been recognised as the most well-managed, clean and safeThey have received a Green Flag Award
Eating OutPub in Lincoln starts selling BOOZY freak shakes - and they look amazingPeople are going crazy for them already
What's On NewsThousands set to attend Vegan Camp-Out festival where 'the vibe is chilled'A 'time for partying, music, and celebrating, mixed with plenty of serious topics'
EventsJoin the hunt for hundreds of years of graffiti etched into Lincoln Cathedral todayHunt for some of the cathedral's most interesting graffiti
Summer Holidays93 ideas for events and activities during the summer school holiday 2019Let us help you plan your summer

redpajama_set_name: RedPajamaCommonCrawl


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Vikramaditya S. Khanna
William W. Cook Professor of Law
Erica Markham
Professor Vikramaditya S. Khanna is faculty co-director of the Joint Centre for Global Corporate and Financial Law and Policy, a collaboration between Michigan Law and India's Jindal Global Law School.
Khanna was the Bruce W. Nichols Visiting Professor of Law in fall 2013 at Harvard Law School. He also was a senior research fellow at Columbia Law School and Yale Law School, and a visiting scholar at Stanford Law School. His interest areas include corporate and securities laws, law and legal issues in India, corporate and white collar crime, legal profession and professional responsibility, corporate governance in emerging markets, and law and economics.
He is the founding and current editor of White Collar Crime eJournal and India Law eJournal at the Social Science Research Network and has served as special master in a dispute involving an Indian and American company. He has testified before the U.S. Congress and his papers have been published in the Harvard Law Review, Journal of Finance, Journal of Econometrics, Michigan Law Review, Supreme Court Economic Review, Journal of Law, Economics and Organization, American Journal of Comparative Law, and Georgetown Law Journal, among others. News publications in the United States, India, Germany, Switzerland, Brazil, and the United Kingdom have quoted him.
He has given talks at Harvard, Columbia, Stanford, Yale, and New York universities; the University of California, Berkeley; the Wharton School of the University of Pennsylvania; the National Bureau of Economic Research; and other venues in the United States, India, China, Turkey, and Greece, among others, including keynotes in the United States, Brazil, and India.
Corporate and Securities Law
Law and Social Sciences
Harvard Law School, SJD
Corporate Lawyer: Law and Ethics
Corporate and White Collar Crime
Law and Economic Development: India
Startup Formation, Funding, and Exits
Startups: Law & Business
U.S. Corp Law / Global Context
"What Rises from the Ashes?"
Iowa J. Corp. L.
"Compliance as Costs and Benefits"
Cambridge Handbook of Compliance
"Corporate Law and Economic Development"
Research Handbook on Comparative Corporate Governance
"Judges in the Lab: No Precedent Effects, No Common/Civil Law Differences"
Journal of Legal Analysis


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The course focus is in teaching with the use of practical training techniques the skills of Car Control.
We do not provide training for any matters under the control of the NSW RMS including licencing or road rules for public roads.
The course is designed for junior drivers from the age of 12 to 18 years old. The course consists of tutorial on car control, safety and car preparation.
Driving instruction is on a one-to-one basis. All instructors have considerable competition driving experience. All instructors are registered and approved for Working with Children Checks, (WWCC).
It is preferred but not essential that participants have some driving experience in sprint karts, motorkhanas, or an RMS learners Permit.
Pupils under the age of 18 years will require a parent or guardian to counter sign the entry form prior to the commencement of each days training activity.
The course contains 6 full days which are conducted per year, both in a practical hands-on and classroom lecture environment.
Please make sure your vehicle is in a road worthy and safe condition. Your car can be road registered or unregistered. Single seat competition vehicles are allowed only with the specific approval of the senior instructor.
Safety apparel required is neck to ankle cotton-based clothing with long sleeves. Shoes should be fully enclosed, of a narrow designed with thin flat soles are preferred.
The car must have two seat belts in good working order.
The car must have a Safety Check each training day, cars not considered save will not be allowed to used until such time it is repaired and made safe.
Before entering a Training Day event the student must first purchase a CAMS L2NSJ or L2SJ licence, please consult with the club for advice. Currently the cost is $ 35.00. The licence is valid for 12 months and is purchased direct from CAMS.
For students who are current financial members of the MG Car Club Ncle the entry fee for CLUB COMPETITION level events are FREE.
For students who are current financial members of the MG Car Club Ncle, all "Young Driver Development Course" (YDDC) days, have an entry fee of $20, commencing from 1st Jan 2019.
ALL YDDC days are conducted at Ringwood Park Motor Sport Complex North of Raymond Terrace.
Dates for YDDC activities are advertised in Club Torque Magazine, Coming Events or on the club website mgcarclub.com.au go to Motorsport, then Calendar, Upcoming Events-Motorsport or you can go to Club Info, Calendar then Upcoming Events then right side box Full Calendar YEAR.


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Lawmakers Pushing Incentives For Cleaner (And Fewer) Cars To Improve Air Quality
By Nicole Nixon • Feb 25, 2019
Sen. Todd Weiler is co-chair of the bipartisan Utah Clean Air Caucus.
Cory Dinter for KUER
Utah lawmakers often claim they have done more in recent years to address the state's poor air quality than ever before. But with a mandate from Gov. Gary Herbert to spend $100 million on air quality this year, legislators say they may fall short, especially with new state revenue numbers showing lower returns than expected.
Rep. Brad Last updated the House on new consensus revenue numbers. Utah lawmakers have $525 million one-time and $570 million in ongoing to spend. Last says it's the best year they've had since the Great Recession. "We do have good revenue, let's use it wisely." #utpol
— Julia Ritchey (@juliaritchey) February 22, 2019
"I don't know if that means air quality gets scaled back to zero or 50 percent or 75 percent" of Herbert's request, said Sen. Todd Weiler, who co-chairs the bipartisan Utah Clean Air Caucus. "Hopefully we'll get some meaningful projects."
Weiler, R-Woods Cross, said he's a fan of what he calls a "cash for clunkers" bill by Rep. Jeff Stenquist, R-Draper, that would provide $3,000-$5,000 grants to help low-income people replace their older cars with newer, cleaner models.
"We're talking about the dirtiest of the dirty cars," Stenquist said of the proposed program. "I think this could be a significant improvement."
The bill is one of a handful aimed at incentivizing cleaner — and fewer — cars on Utah roads.
For example, a bill by Rep. Joel Briscoe, D-Salt Lake City, would create a pilot program for free public transit on certain poor air quality days. Briscoe said research shows that people drive less on "red" days designating poor air quality — yet drive more on "orange" and "yellow" air days than on "green" days.
"So we're trying to get them to extend their concern for air quality beyond just red days to orange days," Briscoe said. His bill comes with a price tag of $1.2 million.
Another bill by Rep. Patrice Arent would pay $6 million for state employees to work from home on poor air quality days.
A hefty $26.5 million funding request by Rep. Stephen Handy, R-Layton, would replace nearly 250 older state vehicles with newer, cleaner models.
"If we didn't do this, it would take ten years of attrition to do it, so this is an opportunity to accelerate. Really, I think it's terrific to have the state lead by example," Handy said.
Other incentives would target emissions from appliances and home tools.
A bill by Rep. Tim Hawkes, R-Centerville, would provide $14 million to assist homeowners in replacing wood-burning stoves and fireplaces with natural gas appliances. Another proposal by Rep. Suzanne Harrison, D-Sandy, would appropriate $3.7 million for people to replace yard equipment such as lawn mowers and snow blowers with electric models.
Utah Clean Air Caucus
2019 utah legislature
#utpol
Why Doesn't Utah's Ozone Pollution Just Blow Away?
By Dan Bammes • Jul 1, 2013
Utah Division of Air Quality
In the winter, air pollution can stay trapped in the valleys of the Wasatch Front until the wind picks up and blows it away. In the summer, ozone pollution can be a problem day after day even when the wind is blowing.
Unlike particulates, which can build up for weeks in a winter inversion, new ozone is created every day by a reaction between tailpipe emissions and sunlight. Erik Crosman, a researcher in the University of Utah's Atmosopheric Sciences program, says the wind doesn't make much difference to pollution levels on a hot summer day.
As Winter Smog Season Begins, Utah Is Acknowledged For Clean-Air Progress
By Judy Fahys • Nov 16, 2018
Judy Fahys / KUER
In one small sign that the state's air-quality cleanup plan is working, the Cache Valley has attained national clean-air standards for winter smog for three years in a row.
© 2020 KUER 90.1
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This the total ultimate package for the entire team. Ordered as a group the best discounts are given and the most products are available.
This package represents the best that you can get and brings each player to $25 for 3 banners and a water bottle. The reason we offer such a discount is because the administration of single orders is huge and building every player is much quicker. So we can pass this along as a team package.
You will be sent a special form for every player to fill out and we will have all the information. As a team you can share equal or split up the package as you desire. You appoint one POC for us and take care of it as a group.
Don't miss out on this great package.


Avengers In Words is a unique partial coverage cross stitch chart measuring 150 stitches wide by 174 stitches high and is available in either a colour chart as per the model stitch, or a black version which the stitcher can choose their own colour choices. This chart is perfect for hand dyed fabric and/or variegated threads.
This chart uses full crosses, French Knots and back stitch makes up the lettering.
The first image shown was stitched by Kim.
The third image is the software generated mock up of the black chart.
If you have stitched this pattern and would like your work used as the product image, please email Kim at KLTcharting@gmail.com with a picture.


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Villa PatriziaDetached villa with pool to Rent and for Sale in Vittoria Apuana Forte dei Marmi
Vittoria Apuana Forte dei Marmi
Located in the area of extreme tranquility and privacy, in the Apuana Victory of Forte dei Marmi, wonderful Detached Villa with pool disposed on three levels, two above ground, just 500 meters from the sea.
Location:Vittoria Apuana Forte dei Marmi
The ground floor consists of a living room with a dining room with access to the veranda with outdoor furniture, a kitchen with a dining area, a bedroom with a double bed, a bathroom with shower and a laundry.
On the upper floor there are four double bedrooms, of which tree with en-suite bathrooms with showers, the master bedroom and a bathroom with shower.
The basement comprises a hot tub, gym, sauna, shower, guest bathroom, bedroom for staff with two single beds and a bathroom with shower, a small kitchen. The basement has a drainage corridor.
The villa is equipped with alarm system, air conditioning, Wi-Fi, floor heating system, wet absorption system, solar panels and video surveillance.
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Villa delle RoseAn elegant, detached villa with a well-kept garden and a pool located in Vittoria Apuana, a quiet area of Forte dei Marmi, about a kilometer from the sea View details Forte dei MarmiVittoria Apuana
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Villa FashionSplendid Detached Villa with swimming pool in the central area of Forte dei Marmi, about 800 meters from the sea. The Villa is spread over 4 levels, and includes 10/12 beds. View details Forte dei MarmiCentro
Villa Cipresso A new, compact villa with garden and a small pool, located in a quiet area of Forte dei Marmi (Vittoria Apuana), about 1 km from the sea. Parking, terrace, sauna View details Forte dei Marmicentro
Villa ViscontiMajestic Villa with swimming pool in the Cinquale area surrounded by 6000sqm of park, with outbuilding and ample parking View details Forte dei Marmi
Villa Benigni A detached villa with a swimming pool located in a quiet and green area of Forte dei Marmi, about 2000 meters away from the sea View details Forte dei MarmiVaiana
Villa Aeternitas View details Forte dei MarmiVittoria Apuana
Villa AliasSplendid Detached Villa with swimming pool, located in the central area of Forte dei Marmi, a few hundred meters from the sea. The Villa is spread over three levels, two of which above ground, and is arranged as follows: View details Forte dei MarmiCentro


The USDA's Food Safety and Inspection Service approved Mexican meat plants.
According to the USDA's Food Safety and Inspection Service, the agency has approved nine Mexican meat and poultry plants for export to the US.
FSIS finished a follow-up audit of Mexico's food safety system late last month and "noted significant progress in establishments and the system after implementing corrective action measures," said a spokesperson.
According to reports, the Mexican government has officially notified FSIS that 9 establishments in the states of Nuevo Leon and Sonora are certified as fully compliant with food safety requirements and can therefore export meat products to the US.
There are 45 other Mexican plants which must still pass re-inspection by FSIS.


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Covid-19 is Exposing Inequalities in Health and Wealth, Deaton Testifies
The ongoing Covid-19 pandemic is exposing and exacerbating health disparities in America, with Black and brown communities hit especially hard. This…
WWS Reacts: How Developing Countries Might Grapple with Covid-19
Covid-19 is present in rich and poorer countries alike, but the looming crisis in developing countries — where dense, vulnerable populations make…
Inequality Gap Grew Before the Great Recession and After, Study Finds
The Great Recession hit Americans across the socioeconomic spectrum, with some still working to recover economically. Yet, the drivers behind these…
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Apple is rumored to launch three new iPhones this year. If the rumors are to be believed, one will continue to feature the iPhone X's 5.8-inch OLED display, while there will be a higher-end model with a larger 6.5-inch OLED display. There are also rumors of a 6.1-inch LCD model which will apparently be the lost-cost version.
Now according to KGI Securities analyst Ming-Chi Kuo, more details about the rumored low-cost iPhone has emerged. According to Kuo, he claims that Apple is expected to launch at least two versions of the 6.1-inch model and will be introducing dual-SIM support for iPhones for the first time ever.
The first variant will be the regular 6.1-inch LCD iPhone with one SIM card slot. The other is rumored to offer dual-SIM support but other than that, its specs are said to be identical. On top of that, the LCD models are also said to be considerably cheaper and could be priced starting at $550.
Considering that as it stands the iPhone X costs $1,000 for the base model and with 2018's models being priced upwards of that, $550 does seem like an outright steal at almost half the price. Of course this should be taken with a grain of salt for now, but we'll probably have to wait until the later part of the year for more details.


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Santa Catalina es una localidad del norte argentino, y cabecera del departamento homónimo, provincia de Jujuy. Es la 2.ª localidad permanentemente habitada más norteña de la Argentina, luego de El Angosto. Se encuentra a 67 km al oeste de La Quiaca.

Es un lugar minero, con ex yacimientos auríferos, teniendo en su río la tentación de hallar, mediante un cedazo, pepitas de oro. Hay cría de llamas, ovejas y cabras.

Turismo
 Antigua Iglesia del siglo XVII, con arte de la imaginería colonial. Está frente a la Plaza principal, al lado del viejo edificio de la familia Saravia, formando un conjunto arquitectónico. La torre, de 10 m, tiene tres pisos telescópicos, con el mismo ancho de la nave (10 m), construida por encima del dintel. El atrio, contenido en la torre, sigue a una nave de 32 m, cuyos antiguos altares se reemplazaron por otros del siglo XX.

Santa Catalina también es conocida por la elaboración de quesillos artesanales.

Fiestas Patronales
En la Localidad de Cusi Cusi la Fiesta Patronal se realizan el 3 de Mayo.

Sismicidad

La sismicidad del área de Jujuy es frecuente y de intensidad baja, y un silencio sísmico de terremotos medios a graves cada 40 años.

 Sismo de 1863: aunque dicha actividad geológica catastrófica, ocurre desde épocas prehistóricas, el terremoto del , señaló un hito importante dentro de la historia de eventos sísmicos jujeños, con 6,4 Richter. Pero nada cambió extremando cuidados y/o restringiendo códigos de construcción.
 Sismo de 1948: el  con 7,0 Richter, el cual destruyó edificaciones y abrió numerosas grietas en inmensas zonas
 Sismo de 2009: el  con 5,6 Richter

Fiestas Patronales

Comunidad de Ciénega de Paicone

Parroquias de la Iglesia católica en Santa Catalina

Referencias

Enlaces externos
 Santa Catalina

Localidades rurales de Jujuy
Comisiones municipales de Jujuy
Minas de la provincia de Jujuy
Departamento de Santa Catalina
Cabeceras de departamento de la provincia de Jujuy

redpajama_set_name: RedPajamaWikipedia


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Little 'butterfly whisperer' spreading her wings as TV star with Chris Packham
She has 2,000 followers on Twitter inspired by her passion for nature
Claire Harrison
Nuneaton's little 'butterfly whisperer' is spreading her wings into the world of TV.
It has been one year since Rebecca Bailey first emerged as a big name in the world of conservation because of her love of butterflies, after opening her very own butterfly farm.
The seven-year-old has now has almost 2,000 followers on Twitter and is praised regularly for her inspirational videos and tweets from conservationists to TV presenters alike.
Her videos have caught the eye of some of TV's biggest nature presenters, so much so that she was asked to join Springwatch Presenter Chris Packham on his BioBlitz as a young presenter.
Proud mum Nicola said explained that Chris Packham's step daughter, Megan, who is also a presenter, contacted Rebecca via Twitter and asked her to join in the Kings Dyke Nature Reserve in Cambridgshire.
"I couldn't believe how confident she was in front of the camera, she had memorised an A4 sheet of information, she did us all really proud," she said.
"We were told that Rebecca was the youngest young presenter they had on the Bioblitz and that she did an excellent job."
Rebecca and TV presenter Chris Packham when she was invited to take part in a special day of filming.
That is not all though, the youngster will also be joining Chris Packham with his Peoples Walk for Wildlife on September 22.
She also met Nick Baker, another big name in the world of wildlife and she was asked to do a Podcast interview with Entonation, an American entomologist company, whereby she spoke about her love of butterflies and her YouTube videos.
She has even ventured into book reviews in her Vlog has been told that she has inspired children across the world to learn more about butterflies.
Away from the camera, she is still nurturing her special purple butterfly farm, used to be her wooden playhouse in the garden of the family home. So far this year she has nurtured and released about 90 butterflies.
Rebecca Bailey, the seven-year-old, who has been dubbed the 'butterfly whisperer'.
She has also has a section of the garden which is called 'The Wildflower Patch' where she scattered some meadowmix seeds to help butterflies and bees and other wildlife too.
But her new found fame has not gone to her head: "She is not boastful at all, she just really enjoys talking about her passion," she said.
This weekend the family have been invited to the Countryfile Live event at Blenheim Palace courtesy of Little Folk Gifts, a firm inspired by her work.
"It is so nice that people are so kind to her and so inspired by her," the mum-of-two added.
To follow Rebecca on Twitter, look for @BeccasButterfli.
Nettles and hayfever
Sugar and bees
Trees mysteriously die
Cannabis oil and cancer


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Alphabet Launched A Moonshot Cybersecurity Company That Sounds Like Every Other Cybersecurity Company
By Kate Conger on at
X, the moonshot wing of Google's parent company Alphabet, announced today that a new cybersecurity project called Chronicle is "graduating" to become a fully-fledged company. X functions as an incubator for Alphabet's more experimental endeavours, like self-driving cars or giant balloons that deliver internet connectivity, and Chronicle is the first cybersecurity company it has launched.
According to a blog post from Chronicle's CEO Stephen Gillett, Chronicle is an enterprise platform that will use artificial intelligence and machine learning to "help enterprises better manage and understand their own security-related data." The company will also include VirusTotal, the malware analytics company that Google acquired in 2012.
For a moonshot, none of this sounds very moonshot-y. In fact, it sounds a lot like the pitch for a number of other enterprise cybersecurity companies that have been offering AI-assisted threat detection for years. The concept boils down to the idea that there are more hackers and online threats than there are cybersecurity professionals to respond to them, so the industry needs a boost of artificial intelligence to keep up.
So what's different about Chronicle? "We'll share more on the technology and what differentiates it at a later date," Gillett told reporters this afternoon.
For now, it seems that Chronicle is relying on its association to Google in order to stand out from the AI-assisted cybersecurity cloud. "We have access to—proximity to—some of the best machine learning and artificial intelligence teams in the world," he said.
It sounds like Chronicle will also lean on Google Cloud's storage capabilities, allowing companies to store more threat intelligence data than they could on their own. "We're building and running Chronicle on the same fast, reliable infrastructure that runs a range of Alphabet initiatives," Gillett said.
Just because other companies are making the same product doesn't mean it can't count as a moonshot, X's "captain of moonshots" Astro Teller wrote in a blog post. "I think of it as the 'yeah, yeah' problem. As in, 'yeah, yeah, I know, Internet access is still a problem for billions of people, but existing technologies like cell towers and wifi are going to get us there eventually, right?'" he wrote. "Cybercrime is the latest problem that's slipping into the 'yeah, yeah' zone."
"Providing better capabilities for finding the patterns in that data might not sound like much, but shrinking the time between when an attack starts and when it's discovered (from a few months to a few hours or days) could reduce a lot of damage — and teach us what other technologies and capabilities might help us turn the tide against a widening array of vulnerabilities and attackers," he added.
So, even if Chronicle sounds like exactly what you've seen at a million vendor booths during RSA, X doesn't want you to count it out quite yet. The brand-new company says it already has a handful of Fortune 500 companies as beta testers for its product.
More Security Posts:
By Alex Cranz on 23 Jan 2018 at 6:30PM
Intel is Trying to Fix the Biggest Problem With Its Spectre and Meltdown Patch
By Tom McKay on 21 Jan 2018 at 2:00PM
Twitter Alerts Nearly 680,000 Users They May Have Been Duped by Russian Accounts
By David Nield on 20 Jan 2018 at 1:00PM
How to Keep Your Home Wi-Fi Safe From Hackers
By Sam Rutherford on 19 Jan 2018 at 9:30PM
OnePlus Says Hack Exposed Credit Cards of Up to 40,000 Customers
Kate Conger


Tomislav Piasevoli created a very cool PowerPivot demo where he using a csv file supplied by Vidas Matelis' Analysis Services Blog to analyze the bloggers. Great sample of using PowerPivot!
Next PostPowerPivot DAX, i love it!


A very special personalised children's activity pack suitable for any wedding, prevents children from getting bored and gives them an important mission to complete.
Allow your little flowerigirl to capture the special day from their unique perspective with this personalised This is my day as a flowergirl activity pack that turns in to a completely one of a kind keepsake.
If you haven't seen a wedding captured from the point of view of a eight year old, then you are in for a real treat!
A real gift that keeps on giving, this personalised activity pack makes them feel very special, on what is a big day for them too, and not only does it keep little hands busy, it also allows them to go home with their very own memory book from the day their as a flowergirl.


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List of MoUs/Agreements signed during the State Visit of Prime Minister of Nepal to India
The Prime Minister, Shri Narendra Modi with the Prime Minister of Nepal, Mr. Sher Bahadur Deuba, at Hyderabad House, in New Delhi on August 24, 2017.
S.No. Title of Agreement Nepalese side Indian side
1. MoU on Modalities for Utilization of India's Housing Grant Component to support Reconstruction of 50,000 Houses Mr. Shanta Raj Subedi, Secretary, Ministry of Finance Shri S. Jaishankar, Foreign Secretary, Ministry of External Affairs
2. MoU on Implementation of the Grant Component of India's Post-Earthquake Reconstruction Package in the Education Sector in Nepal Mr. Shanta Raj Subedi, Secretary, Ministry of Finance Shri S. Jaishankar, Foreign Secretary, Ministry of External Affairs
3. MoU on Implementation of the Grant Component of India's Post-Earthquake Reconstruction Package in the Cultural Heritage Sector in Nepal Mr. Shanta Raj Subedi, Secretary, Ministry of Finance Shri S. Jaishankar, Foreign Secretary, Ministry of External Affairs
4. MoU on Implementation of the Grant Component of India's Post-Earthquake Reconstruction Package in the Health Sector in Nepal Mr. Shanta Raj Subedi, Secretary, Ministry of Finance Shri S. Jaishankar, Foreign Secretary, Ministry of External Affairs
5. MoU for Implementation Arrangement on Cost Sharing, Schedules and Safeguard Issues for Construction of Mechi Bridge under ADB's SASEC Road Connectivity Programme (Tranche 2), Funded by GoI Mr. Devendra Karki, Secretary, Ministry of Physical Infrastructure and Transport Shri Yudhvir Singh Malik, Secretary, Ministry of Road Transport and Highways
6. MoU on Drug Demand Reduction and Prevention of Illicit Trafficking in Narcotic Drugs, Psychotropic Substances and Precursor Chemical and Related Matters Mr. Lok Darshan Regmi, Secretary, Ministry of Home Affairs Shri Hasmukh Adhia, Revenue Secretary, Ministry of Finance
7. Agreement on Cooperation in the Field of Standardization and Conformity Assessment Mr. Bishwo Babu Pudasaini, DG, Nepal Bureau of Standards & Metrology Shri Sanjay Singh, Director General, Bureau of Indian Standards
8. MoU between the Institute of Chartered Accountants of India and the Institute of Chartered Accountants of Nepal Mr. Prakash J. Thapa, President, Institute of Chartered Accountants of Nepal Shri Nilesh S. Vikamsey, President, Institute of Chartered Accountants of India
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text:
define(function (require) {
  'use strict';

  var modules = require('modules');
  var authUtils = require('scripts/users/utils/authUtils.js');
  require('scripts/users/controllers/subjects_authorization_modal_ctrl');

  modules.get('a4c-security').directive('alienAuthorizeUsers', ['$uibModal', '$parse', function ($uibModal, $parse) {
    return authUtils.buildAuthorizeModalDirective('views/users/users_authorization_popup.html', 'rest/latest/users/search', 'username', $parse, $uibModal);
  }]);
});

redpajama_set_name: RedPajamaGithub


A catering business with a twist!
This is a brilliant opportunity for an enthusiastic buyer to take over a successful and growing catering business.
This business is currently in high demand and turning over a great profit.
With a solid reputation in the community in Perth, its own website, and a heavy presence on social media pages, this business is a sure-fire winner.
-	Simple business model providing specialise cooked meats, food and salads and customer service to suit any event or function.
-	Catering in homes or venues of customers choice, either indoor or outdoor.
Contact Sam Fazio regarding this amazing opportunity on 0412 440 139.


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About renting a rubbish bin for your trash convenience needs, it is possible to set on your own away from the rubbish disposal problems. Dumpster will reach your job site at your specific regular periods and take away the particular dump with out demanding your current intervention in the act. you can have the facility of inserting the dumpster some time in the cellar which is outside of customer's see. You will practical experience no waiting in the services provided, the particular dumpster will be picked up by the 8 Yard Dumpster in Vance, AL firm Guam at the time laid out in you. The help of garbage container hire company Guam can break your current misconception concerning trash container rental.
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Cleaning out your current garage can seem like an frustrating task, yet chances are that once you get started, you will end up on a rotate and get on your own organized quickly. It might help to break down the position into a couple of easy steps to assist guide the procedure.
Have you viewed your storage area or cellar lately? The majority of us use these spots as everlasting home storage for factors we think natural meats eventually employ. But there's always more factors we could probably need sometime soon, and these areas fill up quickly, often until we would not find some of the things we need one of the clutter.
There are various companies that supply rolloff 8 Yard Dumpster in Vance, AL. A rolloff dumpster is certainly one that gets sent to your property, driveway or even alley, and then gets picked up again if you are done. You will work out a particular rental period together with the company (commonly a week or two). Anyone fill the particular dumpster, they understand it. Your project keeps rolling with schedule and you don't have to be worried about trash mounting up. It's a win-win situation.
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Guam is unincorporated territory of US; it really is one of the a few US territories. Their state builds it's economy primarily on tourism Sector, Department of Defense installments, and regionally owned companies. Guam is the most southern and biggest island inside the Mariana island archipelago and is also the greatest island with Micronesia.
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If you are a roofing company you know you have to keep your roofing jobs shifting. The time to help roof jigs by with the time you might have due to the climatic conditions. You may live in states which get steamy sizzling into the 1990s and 100's or you may possibly live in a suggest that has ferocious winter weather. Together with the seasons this is the reason time constraints, customers are calling a person left and right to get their roof carried out. Some of the patron's roofs are emergencies because they're leaking as well as causing mould to form around the ceilings. You and the crew have to quickly provide your customer a quotation. Once you increase the risk for time to look at the damage and how much you will be charged the customer to repair his or her roof, you can sign the contract to get it done.
Kansas is a US state branded after Kansas river. Their state is surrounded by Nebraska on the northern; Missouri around the east; Okla on the to the south; and Denver on the western. It is split up into 105 areas with 628 towns. The economic system of the state is sustained by both professional and agriculture products.
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The general audience had been relocated from the audience hall to St. Peters's square, because of the expected huge crowd. In sunny weather, the crowd cheered the Pontiff who drove by the faithful in his "Popemobile".
The "Popemobile" stopped occasionally to allow the Pope to put his arm around some kids. There was also a huge number of pilgrims from the Bavarian homeland of the Pope on St. Peter's square.
The pontificate of Benedict XVI will end on Thursday 8:00 p.m.. In the late afternoon, the hustle and bustle of the last days as Pope is over. Then the 85-year-old will fly to the papal summer residence in Castel Gandolfo outside Rome by helicopter.
His last public act will be a farewell to the faithful of the Diocese of Albano from the Loggia of the residence in Castel Gandolfo at 5:30 pm. With the official end of the pontificate at 8:00 pm, also the Swiss Guard will cease their "public service" for the Pope. But the safety of Benedict XVI is guaranteed, the police will take on the guard duty.
Actually, a pope is elected for life, but according to canon law, a resignation is possible. For this, the head of the Church must give no reasons, and also nobody must accept his resignation. However, the withdrawal must be made voluntarily.
The by John Paul II reformed Canon Law (Can. 332 § 2) states: "Should it happen that the Roman Pontiff resigns from his office, it is required for validity that the resignation be freely made and properly manifested, but it is not necessary that it be accepted by anyone." However, in 2,000 years of church history is known only one voluntary resignation. Pope Celestine V resigned voluntarily in 1294, after just five months in office. Church historians speak of an overwhelmed nerd, who could hardly speak Latin.
The Cardinals had only elected him Pope, because they could not agree on another candidate in nearly two years of struggle. Celestine adjourned in a monastery after his resignation. Other historians claim that his successor, Boniface VIII had urged Celestine to resign, and later sent him into monastic imprisonment.
Benedict XVI. announced his retirement on February 11 during a speach to the Cardinals in Latin language. It was actually only due to the clairaudience and the knowledge of Latin of an Italian woman journalist, that the news of the end of the pontificate went around the globe. "When Pope announced he was resigning, I felt weak at the knees", Chirri later tweeted.
This entry was posted in Pope Benedict XVI and tagged 1294, bavarian, canon law, castell gandolfo, Celestine V, cheer, church, crowd, decision, faith, faithful, february 28 thursday, final decision, general audience, gift, intense reflection, John Paul II., last general audience, latin, moved, new pope, pilgrims, Pope Benedict XVI, prayer, reflection, resign, Resignation, safety, speech, St. Peter's square, strenth, successor, thursday, voluntarily, voluntary by Osservatore. Bookmark the permalink.
THE ALMIGHTY GOD BLESS YOU RETIRED HOLY FATHER.WE ARE ALL TOGETHER.THANKS!!!


Sand making machine is also calledcobble sand maker and the core equipment in artificial mechanism sand production. It has high crushing performance and output, which is able to meet the requirements of sand and stone aggregates.
But through years of exposure to sun and rain, or the self operation problem, the machine working efficiency will become low and the main spare parts like bearing, impact block (called hammer board), impact liner plate, and rotor cover, etc. will be worn. How to make these parts playing the best role, and prolonging the service life?
Firstly, let's know about bearings of sand making machine. Bearings are used to fix hammer head and impacting plate or hammer board to make it fit well with motor. Moreover, the machine's rotating device and driving device are connecting through bearings, so the bearings are the necessary parts of the crusher. The lubrication oil and lubricant are used to lubricate the bearings, which can effectively reduce the wear and tear, and extend the service life.
Secondly, let's talk about the solution of sand making machine abrasion. Impacting block (hammer board) is the most serious worn part in the process of sand making, so what are the affecting factors? Excluding the normal abrasion, the processing capacity also has influence on the hammer board. When the processing capacity is increased, the products granularity becomes coarse; the crushing ratio is decrease, so the unit abrasion of hammer board is lower. At the same time, changing the discharge gap is able to change the particle size, so as to influence the abrasion situation.
In addition to the above situation, the daily inspection is necessary. After each shift, the workers should take fully inspection, especially on the bearing, impacting plate, and liner plate. The gap between rotor and impacting plate can be adjusted if necessary to relieve the parts abrasion.
Next Article: How to improve the Working Efficiency of Ball Mill?


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Nick Page
Nick was previously a daytime TV presenter, before being sacked from the BBC for an incident involving an antique rocking horse and a four-poster bed. He also had a Radio 4 show about farming which somehow led to him sailing a bathtub downriver to Brighton. In short, he is more than just your run of the mill comic. All of his stories are very personal and revel in the kind of wrongness most people would want locked in the darkest cupboard.
"The best story teller on the circuit" - Rhod Gilbert
Have a look Who's in the Gallery
Take me there >
The Funny Side was great!
Thanks once again for last night. My whole team are absolutely raving about it, which is slightly annoying as it was my best kept secret! You're an absolute legend.
A great show at the Funny Side last night. Well done! Laughed a lot! Great acts and funny compere. Merry Xmas.
Nice venue. Great comedians and a good compere. Really helpful staff.


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Khan Murad Basha
Ma'arrat al-Nu'man, Syria
Murad Basha Khan is a large caravanserai located near the center of Ma'arrat al-Nu'man. An inscription above the entrance portal attributes the building to the patronage of Murad Çelebi, the chief financial officer (daftardar) of the Ottoman Empire (d. 1573-1574/981 AH). With an area of 7 dunam (an Ottoman measurement equivalent to ca. 7,000 square meters), it is the largest caravanserai in Syria. The site was restored in 1985 and converted to a museum.
The building is large square with a central courtyard and an appendage on its western side. Its main entrance is on the south side through a large portal in the form of an iwan. Entering the portal, one emerges onto the southern portico of the courtyard, which is surrounded on all sides by arcaded porticoes one aisle deep. A rectangular building that houses a mosque occupies the center of the courtyard. Off the porticoes along the perimeter of the square building are rooms for guests.
Murad Basha Khan was damaged in the Syrian conflict of 2015, and some 30 artifacts were stolen from the museum.1
Syrian Directorate-General of Antiquities and Museums. Interactive Map of Conflicted Sites. http://www.dgam.gov.sy [Accessed 14 February 2018].
Burns, Ross. Monuments of Syria, 147. London: I. B. Tauris, 1992.
Elisséeff, Nikita. "Ma'arrat al-Nu'man," Encyclopedia of Islam, Second Edition, 2012.
http://dx.doi.org/10.1163/1573-3912_islam_COM_0598
[Accessed 13 February 2018].
Maʻarrat al-Nuʻman
Site Contains
Murad Pasha Caravanserai Restoration
1566-1567/974 AH
restored in 1985
destroyed in 2015
7 dunams (ca. 7,000 square meters) (area)
خان مراد باشا
Transliterated
Khan Murad Pasha
Murad Pasha Khan
Murad Pasha Caravanserai
ICR2122
Ma'arrat al-Nu'man. Murad Pasha Caravanserai. Exterior View.
35 mm color slide
Ma'arrat al-Nu'man. Murad Pasha Caravanserai. Portal.
Ma'arrat al-Nu'man. Murad Pasha Caravanserai. Courtyard Mosque.


text:
Harvests of Joy: How the Good Life Became Great Business
by Robert Mondavi, Paul Chutkow (With)Robert Mondavi
Paperback(First Edition)
HMH Books
Harvest Book Series
Edition description:
Robert Mondavi (1913–2008) founded the Robert Mondavi Winery, one of the most respected wineries in the world. He was the recipient of numerous honors and awards, including Winemaker of the Year and the Harvard Business School Association Business Leader of the Year.
At the age of fifty-two, I should have been a happy man.
On the surface, life was good. The year was 1965, and America was prospering. I had a lovely, devoted wife, three delightful children — Michael, Marcia, and Tim — and we lived in what I knew was one of the most idyllic spots on the planet, the Napa Valley. For twenty-three years my brother, Peter, and I had been running a small family business, the Charles Krug Winery, and we were doing pretty well. While my wife Marge and I had to be very careful about what we spent, we were secure enough to live comfortably and provide for our children.
I also adored my work. For some people in the Napa Valley, wine was just a business, an agreeable way to earn a living. Not for me. Wine for me had always been something much larger and it still is. Wine to me is passion. It's family and friends. It's warmth of heart and generosity of spirit. Wine is art. It's culture. It's the essence of civilization and the Art of Living. Wine has been with us for seven thousand years, almost since the dawn of civilization, and for centuries poets, painters, musicians, and philosophers have sung its praises. Even the Bible applauds its virtues. And wine to me is even more. When I pour a glass of truly fine wine, when I hold it up to the light and admire its color, when I raise it to my nose and savor its bouquet and essence, I know that wine is, above all else, a blessing, a gift of nature, a joy as pure and elemental as the soil and vines and sunshine from which it springs. "Wine is Life," Petronius said two thousand years ago, and I know exactly what he meant.
For most men and women, what I had would have been the makings of a wonderful, contented life. But not for me. In truth, I was feeling stifled at Krug. Like so many people who reach a critical juncture in their lives and careers, I felt I was not making the most of my business savvy and creativity. I was working hard, as always, but my enthusiasm was on the wane. Throughout the 1950s and early 1960s, we had been making good table wines at Krug. We were considered to be among the "Big Five" of the Napa Valley, along with Beaulieu Vineyard, Inglenook, Louis Martini, and Beringer Brothers. We had built our reputation on the strength of our white wines, and our cabernet sauvignon was considered among the best in the valley. Still, I felt our ambitions were just too tame. We in California had enormous potential; I knew we could become one of the great wineproducing regions of the world. But the American wine industry was still in its infancy, and no one seemed to have the knowledge, the vision, or the guts to reach for the gold, to make wines that could stand proudly next to the very best from France, Italy, Germany, and Spain.
I wanted to move Krug in a bold new direction. In 1962 I had traveled around Europe for the first time, visiting many of the great wine-producing regions of the world to see how they made their wines. In Bordeaux, Burgundy, Tuscany, and the Moselle region of Germany, I explored some of the most prestigious wineries in the world. I toured their vineyards and cellars, examined their equipment, talked with their wine makers, and, of course, tasted their wines. Above all, in these vineyards and cellars and tasting rooms, I imbibed the spirit, the passion, and the commitment that inspired the creation of truly great wines.
Much of what I saw was a revelation. At the great chateaus, the way of growing grapes and making wine was far different from what we had been doing for generations in California. While we had one basic approach for our red wines and another for our whites, their approach was far more subtle and sophisticated. They treated each variety of grape differently, and they had a distinct method and style for each type of wine they made. We made wines in bulk, using huge tanks; they kept their output small to maximize quality, and they aged their wines in small oak barrels to create gentleness, subtlety, and complex layers of flavor. The differences ran much deeper than method and equipment. We were a big, young country, oriented toward mass production and scientific research, and in our wine making we emphasized crop yields, sugar levels, and profit margins. The great European wineries, with centuries of tradition and craft behind them, put their emphasis on less tangible qualities such as style, character, and bouquet. To my mind, the contrast was stark: we were treating wine as a business; the great European chateaus were treating wine as high art.
This realization stirred something deep inside me, but I did not understand what until one day when Marge and I had lunch at La Pyramide, one of the great restaurants of France and the world. I still remember that day vividly. I had a meeting that morning in Lyons with a potential business associate, and Marge and I had a huge breakfast with him. Talking, discussing business, we lingered at the table until about eleven o'clock. "My god," I thought, "here we're going to have lunch in one of the best restaurants in the world, one with three stars in the Michelin Guide, and I'm already stuffed! What am I going to do?"
An hour and a half later, we drove into Vienne, a little village outside Lyons, and found our way to La Pyramide. The setting and atmosphere of the restaurant were tasteful and elegant, without being pretentious, and we sat down to a meal that was absolutely unbelievable. Each and every dish we tried was heavenly and distinctive, with flavors I had never tasted before. Nothing was heavy or too filling, and there were none of those rich cream or butter sauces you found in many French restaurants in those days. Every forkful was light and pure in the mouth; in every bite we could taste the passion and the artistry of the chef.
What really dazzled me was how each dish complemented and enhanced the other, the way the sounds of different instruments meld into a symphony. The wines we tasted during the meal were not big and bold like ours in California; they were gentle and complex, and they artfully accentuated the many sensations and feelings that the cuisine inspired. I'd go so far as to say that the food and the wine transported us into a world of gentleness and balance, of grace and harmony. La Pyramide to me epitomized the artistry and aesthetics we had been discovering all across Europe, and it inspired in me both a vision and a vow:
"This is the kind of wine I want to create," I told Marge. "Wines that have grace and style, harmony and balance."
During my travels in Europe, I was impressed with something else: an opportunity. I saw great extremes in wine making in Europe. The First Growth Bordeaux châteaus — Château Mouton-Rothschild, Château Lafite, Château Mar-gaux, Château Haut-Brion, and Château Pétrus — made marvelous wine, subtle and complex, with flavors that were always crisp and clean. And I discovered the reason: these top châteaus were all using only new French oak barrels. Almost everyone else was producing wine the exact same way their forefathers had, and the results were not, to my taste, exceptional. I found many supposedly fine wines that proved to have off characters and bacterial defects. And I saw why: they were making their wine in oak barrels that were used, not new. This was one reason for those sorts of defects and "spent" flavors. To my critical eye, many of the European producers seemed to be asleep, content with the status quo; and so, frankly, I saw an opening. I felt certain that we in the Napa Valley could do just as well or better! It would take time, patience, money, and a full-blown education in how to make wine the way the great Bordeaux cháteaus did, but I felt sure we could succeed. And what an exciting challenge it would be!
I left Europe elated. Some of the wines I had tasted there were exceptional, but I believed that we in California could do just as well and, in time, even better. Our soil, climate, and rootstocks were just as good as what I saw in Europe and in many ways better. We also had the right varieties of grapes to make great wine: cabernet, pinot noir, chardonnay, and sauvignon blanc. True, we did not have the Europeans' know-how or their craft and tradition. But I felt absolutely certain that we could learn quickly and make significant leaps in the quality of our wines. Over the following days, a great business and creative venture took shape before my eyes: I wanted to take American technology, management techniques, and marketing savvy and fuse them together with Old World tradition and elegance in the art of making fine wine. We would need passion, conviction, and courage, along with a willingness to invest in the necessary research, development, and new equipment. But with this combination, I felt confident that Napa Valley and California could ultimately create wines that would stand shoulder to shoulder with the great wines in the world.
I returned to the Napa Valley energized and ready to go. I wanted Krug to take up the challenge, jump in with both feet. I wanted us to shed our inhibitions, our complacency, our contentment with the status quo. I wanted my family and our company to commit ourselves to a true quest for excellence in our vineyards, in our wine making, and in our marketing and sales. The Napa Valley, in my view, was ready for just this sort of challenge. We were, in fact, a sleepy little farm community, with no sophistication, little economic vitality, and no fine restaurants. Our wine industry was by no means vibrant, either. At the time, we had only about twenty wineries in the whole valley, and only a half dozen were making quality wine. The situation around the state was not much better. The bulk of production in California at that time was jug wine, and the largest producers were Italian Swiss Colony in Asti, Roma Wine Company in Lodi and Fresno, and Ernest and Julio Gallo, located farther south in the Central Valley. But to me the potential was clear. We had magnificent climate and vineyards, a beautiful landscape, and proximity to cosmopolitan San Francisco. I was sure that we had what it took to become one of the great wine-producing regions of the world — provided someone would take the lead. I wanted that someone to be Krug.
I pushed my ideas hard inside Krug and with my family, and I did so in my usual ebullient, single-minded way. But the harder I pushed, the more resistance I encountered, especially after my father passed away. My father had always been open to my suggestions. To most of my family, what I was pushing sounded risky and pointless. We already had a respected business, and our extended family lived comfortably on the beautiful, historic grounds of the Krug Winery. So why rock the boat? Why tamper with our modest but stable success?
So I was stymied. We were a family business; I could not make decisions on my own. In our corporation, established in 1946, my parents controlled 40 percent of the stock. My brother, Peter, and I each had 20 percent, and my sisters, Helen and Mary, had the remaining 20 percent. When my father died in 1959, he left control of the corporation in the hands of my mother, who had no experience in business. We were a comfortable family business, but I felt we needed a great dream, a defining mission, a higher calling. I made my case again and again, but no one in the family, apart from Marge and my children, shared my larger vision. So in the months and years that followed, my frustrations only deepened.
I gave my younger brother, Peter, the most heat. Ever since childhood, our temperaments and ambitions had been to very different, but we had followed parallel paths. In high school I played football, then he played football. I went to Stanford, then he went to Stanford. After graduation, I spent part of my summer vacation being tutored in wine making by Professor Vic Enriques of U.C. Berkeley. Peter later studied wine making at U.C. Berkeley. Then I did an apprenticeship in wine making in the Napa Valley; Peter did an apprenticeship at a winery down in California's Central Valley. In 1943, when I talked my father into buying the Charles Krug Winery, Dad had only one condition: that Peter and I run the business together. We agreed. Peter was serving in the U.S. Army, at the height of World War II, and so I set up all the wine-making operations at Krug. After the war, I took charge of marketing and sales and turned over the wine making to Peter. In the years that followed, we often clashed about wine making and other business matters, but whenever we failed to sort things through, my father would always step in and settle the dispute. After he died in 1959, we held an even keel for a while. But when I returned from Europe in 1962 and urged Peter to make dramatic changes to upgrade the quality of our wines, he really got his back up. I guess Peter felt I was encroaching on his turf. For my part, I felt Peter just did not share my ambition to commit Krug to the challenge and demands of making world-class wines. Peter, of course, might dispute that, but then again we always seemed to disagree and see things from very different perspectives. We still do!
At heart, I think it was a question of temperament. Peter was quiet, gentle, and self-effacing, a family man who loved to fish and adored spending time with his wife and children. When he was a small boy, the family affectionately nicknamed him Babe, and more than forty years later everyone in the family still called him that. By contrast, I was always hard driving and ambitious, and no one ever accused me of being quiet or self-effacing. I never had enough time to fish; I was always too busy thinking of ways to improve our wines and grow our company. My business goals were clear and far-reaching: I wanted Krug to pioneer a whole new approach to wine making in America. Through our work and that of like-minded wineries, I dreamed of putting the whole Napa Valley onto the map of world-class wines, right beside Bordeaux, Burgundy, and Tuscany. Peter, I imagine, thought I was an ego out of control.
My vision for the Napa Valley did turn out to be prophetic, of course, but Destiny did not play out quite as I had anticipated.
Looking back now, I guess the turning point came the year after I returned from Europe, on a fall afternoon when we were busy harvesting at Krug. In the mail that day, in an envelope with fancy lettering and a golden seal, I received a startling invitation. President John F. Kennedy was inviting me and Marge to attend a state dinner at the White House. The dinner was to honor the prime minister of Italy, and I was asked to attend as part of a group of prominent Italian Americans. I took the invitation as a tremendous honor and a golden opportunity for the Charles Krug Winery. President Kennedy and Jackie apparently wanted to show the Italian leader that our young country was starting to make some pretty good wines.
Flattered though we were, Marge and I were very nervous. After all, we came from what was then a small, struggling farm community. We had no wealth and next to no big-city sophistication. We were just small-town people running a small family business. So Marge and I were worried: How in the world would we fare at the Kennedy White House, with the charismatic president and his famous wife, surrounded by all the glamour of Camelot? Marge also had a more specific worry: What in the dickens should she wear to a White House dinner? What dress? What shoes? What bag? What jewelry? What coat?
Marge was particularly worried about a winter coat. She had a coat that was fine for the mild, damp winters in St. Helena, but it was not stylish, nothing suitable to meet a first lady who was always elegantly outfitted by the finest designers in Paris. In search of a solution, Marge went to the modest shops in St. Helena and the town of Napa, but she found nothing to her liking. So one day I took off from work and we drove into San Francisco to shop in the big department stores and fashionable boutiques around Union Square.
We both knew, though, that we had to be careful. The Charles Krug Winery was by no means booming and we had three children to feed, clothe, and put through school. As I recall, at that time I was earning only about $24,000 a year; hardly a princely sum. So after a thorough review of what we could afford, I had budgeted up to $1,500 for a coat for Marge. Even that was a stretch, but how many times in your life do you get invited to the White House? We went to I. Magnin and Marge tried on several different coats. None really caught her fancy and none seemed suitable for a dinner at the White House. Then the saleslady brought out something special: a mink coat. Mink! And it was gorgeous. Right away we both knew it would look perfect on Marge and it was just the thing to wear to the Kennedy White House. Alas, we also knew it would be way too expensive for our modest means. Prudence told us to stop right there and run out of the store. On a lark, though, Marge decided to try on the coat, just to see how she'd feel wrapped in mink. Well, the coat fit perfectly and Marge looked smashing. She loved the way it made her look and feel. Still, the price tag was a staggering $5,000, way beyond our means, and that was that. We left I. Magnin thinking, "Oh well, maybe one day, maybe one day ..."
(Continues…)
Excerpted from "Harvests of Joy"
by .
Copyright © 1998 Robert Mondavi.
Excerpted by permission of Houghton Mifflin Harcourt Publishing Company.
All rights reserved. No part of this excerpt may be reproduced or reprinted without permission in writing from the publisher.
Title Page,
Table of Contents,
Epigraph,
THE ROOTS,
A Passion for Perfection,
To Kalon,
The Innovators,
The Extended Family,
Good as Gold,
The Touch,
The Breakthrough,
THE FLOWERING,
Marrying Wine and the Arts,
Bring on the Baron,
The Revolution,
Prices to Pay,
The Gamble,
THE HARVEST,
To Be a Pioneer,
The Future of Wine Making,
Globalization,
The Feast,
Acknowledgments,
No one has been more closely associated with the California wine revolution than Robert Mondavi. Probably because he started it."-the New York Times
"The hottest wine book for holiday gift-giving is Robert Mondavi's new autobiography Harvests of Joy."-The Ottawa Sun
"For businessmen and dreamers, here's business advice mixed with inspirational enthusiasm from a man who . . . built himself into a world-recognized symbol of quality California wine."-Wine & Spirits
book by amy rusch
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by Ian Kershaw
From the preeminent Hitler biographer, a fascinating and original exploration of how the Third Reich was willing and able to fight to the bitter end of World War II.
Countless books have been written about why Nazi Germany lost World War II, yet remarkably little attention has been paid to the equally vital question of how and why it was able to hold out as long as it did. The Third Reich did not surrender until Germany had been left in ruins and almost completely occupied. Even in the near-apocalyptic final months, when the war was plainly lost, the Nazis refused to sue for peace. Historically, this is extremely rare.
Drawing on original testimony from ordinary Germans and arch-Nazis alike, award-winning historian Ian Kershaw explores this fascinating question in a gripping and focused narrative that begins with the failed bomb plot in July 1944 and ends with the German capitulation in May 1945. Hitler, desperate to avoid a repeat of the "disgraceful" German surrender in 1918, was of course critical to the Third Reich's fanatical determination, but his power was sustained only because those below him were unable, or unwilling, to challenge it. Even as the military situation grew increasingly hopeless, Wehrmacht generals fought on, their orders largely obeyed, and the regime continued its ruthless persecution of Jews, prisoners, and foreign workers. Beneath the hail of allied bombing, German society maintained some semblance of normalcy in the very last months of the war. The Berlin Philharmonic even performed on April 12, 1945, less than three weeks before Hitler's suicide.
As Kershaw shows, the structure of Hitler's "charismatic rule" created a powerful negative bond between him and the Nazi leadership- they had no future without him, and so their fates were inextricably tied. Terror also helped the Third Reich maintain its grip on power as the regime began to wage war not only on its ideologically defined enemies but also on the German people themselves. Yet even as each month brought fresh horrors for civilians, popular support for the regime remained linked to a patriotic support of Germany and a terrible fear of the enemy closing in.
Based on prodigious new research, Kershaw's The End is a harrowing yet enthralling portrait of the Third Reich in its last desperate gasps.
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Ian Kershaw - Author


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