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New restaurant pops up in Des Moines
All-star team offers taste of Southern comfort for limited time
Updated: 10:32 PM CST Jan 11, 2013
A brand new restaurant has popped up for a limited time in Des Moines."It's January, there's not much else to do, (so) let's put on our eating clothes and go eat some down-home Southern food," said Chris Diebel, co-creator of Bubba Southern Comfort. "A concept like a pop-up restaurant really helps break up the monotony of winter."Offering a taste of Southern comfort, Bubba Southern Comfort is inside Hoyt Sherman Place only until Sunday."We've had to literally, from scratch, create a front-of-house staff, a back-of-house staff. We've had to do decor, we've had to do branding work. It's been a long road," Diebel said."I think it's a great opportunity to have a very specialized meal, (where) anything can happen. It's like a live show, so it's very exciting to see how he's presenting everything," said guest Angela Bohnenkamp.An all-star team, made up of chefs from different restaurants, is working behind the scenes."Back here, (we have) Jonathan from Hilton Garden Inn, Tony from Zombie Burger, Derek from Centro, Fabio from Django. We have people from everywhere," said chef Scott Stroud.The chefs said they're used to memorizing menus, but it's a little different when the restaurant exists only for three days."We're worried, like, is this going to work? In reality, this is the A-squad here. We brought the people who can say, 'Hey, give me a new menu. I'll have it figured out in 20 minutes and just go,'" said Stroud.Reservations are booked solid, but Diebel said it won't be long until another pops up."We're letting all the chefs come up with their own things. I wouldn't be surprised if we saw some outdoors, if we saw some traditional restaurant spaces. It could be any number of things," Diebel said.
DES MOINES, Iowa —
A brand new restaurant has popped up for a limited time in Des Moines.
"It's January, there's not much else to do, (so) let's put on our eating clothes and go eat some down-home Southern food," said Chris Diebel, co-creator of Bubba Southern Comfort. "A concept like a pop-up restaurant really helps break up the monotony of winter."
Offering a taste of Southern comfort, Bubba Southern Comfort is inside Hoyt Sherman Place only until Sunday.
"We've had to literally, from scratch, create a front-of-house staff, a back-of-house staff. We've had to do decor, we've had to do branding work. It's been a long road," Diebel said.
"I think it's a great opportunity to have a very specialized meal, (where) anything can happen. It's like a live show, so it's very exciting to see how he's presenting everything," said guest Angela Bohnenkamp.
An all-star team, made up of chefs from different restaurants, is working behind the scenes.
"Back here, (we have) Jonathan from Hilton Garden Inn, Tony from Zombie Burger, Derek from Centro, Fabio from Django. We have people from everywhere," said chef Scott Stroud.
The chefs said they're used to memorizing menus, but it's a little different when the restaurant exists only for three days.
"We're worried, like, is this going to work? In reality, this is the A-squad here. We brought the people who can say, 'Hey, give me a new menu. I'll have it figured out in 20 minutes and just go,'" said Stroud.
Reservations are booked solid, but Diebel said it won't be long until another pops up.
"We're letting all the chefs come up with their own things. I wouldn't be surprised if we saw some outdoors, if we saw some traditional restaurant spaces. It could be any number of things," Diebel said.


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The Best Residential Architects and Designers in Boston
The Best Residential General Contractors in Boston
The Best Commercial Architects in Boston
Best Design-Build Firms & Custom Home Builders in Boston
The Best Restaurant Architects and Designers in Boston
As a food destination, Boston never disappoints. From award-winning chefs and avant-garde restaurateurs to college diners and neighborhood go-to's serving beloved comfort food, Beantown has much to offer. Eateries spanning a world of cuisine are opening — from Roxbury to Cambridge — without any regard for what is #trending. With this new generation of culinary innovators come restaurant spaces that are as fresh as the next menu. Here are the top architects designing forward-thinking restaurants to complement Boston's progressive palate.
Top Architects and Designers
Analogue Studio
Principals:
Vinc Pan
Brian Amaral
Brendan Bergantino
Stephanie Collins
Boston Magazine Boston's Best Businesses
129 South Street, 5th Floor, Boston, MA 02111
WordPress Portfolio
About Analogue Studio
With a team of seven designers and architects — including Brian Amaral, AIA, Brendan Bergantino, and Stephanie Collins IIDA, LEED AP — Analogue Studio has amassed a list of commercial, corporate, and hospitality clients that include Legendary Entertainment, Duck & Chicken Restaurant Group, Workbar, and the Boston Society of Architects. The firm's founder and Principal Vince Pan AIA, BSA, LEED AP, graduated from Princeton University with a Master of Architecture. In 2011 he established Analogue Studio, a design company Architect Magazine has counted among their top 50 architecture firms in the United States. Contract Magazine, Boston Globe, Women's Wear Daily, and Design Bureau have taken notice of Analogue Studio designs throughout Boston.
Analogue Studio designed Night Market, which brings Asian street food to Cambridge. Duck & Chicken Restaurant Group tapped the firm to draw on all of their design services, to take the Harvard Square restaurant from an idea to an experiential eatery. With Analogue Studio architecture and branding, the basement space transformed into a bustling, outdoor alleyway, with columns wrapped in graffiti, exposed brick and stone walls, and brick floors. Wood cladding made of mismatched planks suggest a makeshift food stall. Another Harvard Square restaurant, Parsnip, is a totally different yet also successful Analogue Studio space. The two-story space features a refined dining room on the main floor, under a second-story, Mid-century lounge. The design team collaborated with the executive chef to lay out a kitchen that would serve both levels. Analogue Studio outfitted Parsnip with custom furniture pieces and two boomerang-shaped bars that recall 1950s curvatures. The dining room features a herringbone, wood floor, and intimate alcoves. Upstairs, a black, slatted ceiling absorbs light that passes through the landmarked building's large, round windows.
Bentel & Bentel
Frederick R. Bentel
Maria A. Bentel
Paul Bentel
Peter Bentel
Carol R. Bentel
Jamaes Beard Awards,
Hospitality Design Hall of Fame,
Archi Awards,
SARA National Design Award
22 Buckram Road, Locust Valley, NY 11560
About Bentel & Bentel
Sixty-year-old architecture firm Bentel & Bentel is based in Locust Valley, New York, but the firm's leadership team has deep New England roots. The late founders and couple, Dr. Frederick R. Bentel, FAIA, and Maria A. Bentel, FAIA, graduated with architecture degrees from the Massachusetts Institute of Technology. Still a family-run practice, Bentel & Bentel is now led by partners Dr. Paul Bentel, FAIA, Peter Bentel, AIA, and Dr. Carol R. Bentel, FAIA, ASID, IIDA. The firm's Boston hospitality projects have earned 3 James Beard Awards, Archi Awards and a SARA National Design Award. The three partners also made it into the Hospitality Design Hall of Fame, and Carol and Paul are Fellows of AIA. They have also landed in the pages of Boston Magazine, Boston Globe, Interior Design, and Hospitality Design.
The Bentel & Bentel design for Houston's played off nearby architecture and Boston's colonial history. The external structure for the 9,000-square-foot restaurant was designed to be a stylistic fulcrum between the surrounding classical buildings and the contemporary monoliths that have begun to permeate the landscape. Tucked under a plaza, the bronze and glass facade recalls Quincy Market's cupolas and domes, but the contemporary lines belie an aesthetic seachange and nod at the simplicity of nearby storefronts. Inside, the finishes are similarly layered in intent. Oiled stone, leather, and wood glow under warm, modern lighting. The design was recognized with an AIA Long Island Chapter Design Award and a National Honor Award from SARA. In another successful comingling of contemporary and classic vernaculars, Bentel & Bentel designed B&G Oysters, a South End locale helmed by Chef Barbara Lynch. Marble counters and glass tiles lend unpretentious luxury to the classic New England seafood fare. The ceiling and the wall opposite the kitchen are dressed in a rhythmic pattern of flat and recessed bleached wood panels, adding depth to the restaurant without overwhelming the small space.
Other notable and more recent work include Garrett Harker's Les Sablon, Benedetto for chef Michael Pagliarini, Row 34 and Island Creek Oyster Bar for Garrett, Island Creek Oyster Bar in Burlington, and Row 34 in Portsmouth New Hampshire
Bergmeyer Associates
51 Sleeper St., 6th Floor, Boston, MA 02210
About Bergmeyer Associates
Bergmeyer is a group of architects, strategists, brand specialists, and interior and graphic designers who work together as a Design Collaborative. Its design approach forges proactive connections with clients and project teams to foster a shared sense of ownership throughout the whole creative process. Bergmeyer's services encompass architecture, interior design, branding and graphic design, visual merchandising, program management, sustainability consulting, placemaking, and event design. These services cater to retail, restaurant, workplace, commercial, residential, academic, cultural, hospitality, and healthcare markets.
Bergmeyer has worked on award-winning restaurants with COJE Management Group multiple times. Lolita, one of their collaborations, has earned a Design of the Year award from Eater Boston. COJE Management led the design for Lolita. As Project Architect, Bergmeyer worked closely with their team to bring their dramatic vision of an Old Spanish setting to life. A provocative journey of the senses, Lolita's sprawling space is nestled along the water in Boston's Fort Point neighborhood. The design is anchored on bold colors and playful interpretations of The Day of the Dead. The overall aesthetic is reminiscent of a reclaimed church and befits the location—a basement space of a building that dates back to 1902. Bergmeyer successfully converted the former storage area into an alluring restaurant complete with leather seating, an altar-like bar, hand-painted "stained glass" artwork, full wall murals, and a skull-covered ceiling. Lolita was also honored by the Retail Design Institute in 2017.
BKA Architects
Barry Koretz
David Seibert
Keith Bettencourt
Kevin Paton
Mindy Kaplan
344 Boylston Street, Boston, MA 02116
About BKA Architects
An international, full-service architecture and interior design firm, BKA Architects has designed residential and commercial environments since 1974. Founded by Principal Emeritus Barry Koretz, who is a member of American Institute of Architects (AIA), and the team of 40+ designers and administrative staff is now led by President David Seibert, AIA, and Principals Keith Bettencourt, AIA, and Kevin Paton, AIA. With Interior Design Director Mindy Kaplan, member of the International Interior Design Association IIDA, a Leadership in Energy and Environmental Design Accredited Professional (LEED AP), certified by the Council for Interior Design Qualification (NCIDQ), the leadership team has steered the firm to complete projects featured in Business Insider, The Boston Globe, and Boston Magazine.
Sweetgreen tapped BKA Architects for their expansion to Summer Street in the Financial District. The firm combined the existing architecture with the salad chain's prototypal design features. The corner location is wrapped in broad windows, bathing the interior in natural light. Grooved columns frame the service counter, a clean, white volume set under a bright white overhang. Wood accents, like the stepped entryway, warm the slate-colored floors. At the Sweetgreen School Street outpost, BKA Architects also integrated different original architecture, in deference to the history of Downtown Crossing. Here, sealed concrete floors and exposed brick show patina, while white cladding bridge older elements with the company's clean aesthetic. For a new frozen yogurt spot, BKA Architects designed a location and a brand that would set the business apart from its crowded category. The result is Discoyo in North Easton, where customers dispense frozen treats from machines built into a multicolor, fluted alcove, then enjoy their dessert concoctions in white, tufted booths or a lounge furnished with LED seating.
Hacin + Associates
David Hacin
IIDA New England Hospitality Design Award
500 Harrison Avenue, Studio 4F, Boston MA, 02118
About Hacin + Associates
A New England Design Hall of Fame inductee, David Hacin, FAIA, established Hacin + Associates, a South End team of more than 20 designers. Twelve years after its founding, the architecture firm expanded to provide interior design services, and they eventually would also offer graphic, exhibit, and furniture design. Through their partnership with Sasaki Associates, Hacin + Associates works toward sustainable and boundary-pushing advancements in architecture. Hacin is a member of the Boston Civic Design Commission and a co-founder of the Design Industry Groups of Massachusetts. Under his direction as principal and creative director of Hacin + Associates, the firm's restaurant projects have drawn attention from Interior Design magazine and earned a Hospitality Design award from the International Interior Design Association New England chapter.
Dubbed as a 'subterranean oasis', South End restaurant Shore Leave is a tiki bar and food destination located 20 feet below street level. Inspired by America's tiki culture, Hacin + Associates' design went beyond stone and wooden figures to include a highly considered selection of tropical and mid-century modern elements. The space includes communal booths, private tables, and three bars, seating about 100 guests. The project has been highlighted by Boston Magazine, Eater Boston, and Improper Bostonian. The firm is also up for a James Beard Foundation Outstanding Restaurant Design award. In District Hall, Hacin + Associates designed the restaurant + cafe duo, Gather & Brew. Gather is meticulously lit to complement — and not distract from — floor-to-ceiling windows and views of the harbor and Institute of Contemporary Art beyond. The articulated, wood-panel ceiling — milled by computer numerical control — holds dozens of dangling bare bulbs, reflecting their glittering light. Brew is situated along District Hall's central corridor, drawing guests into a comfortable seating area that invites collaboration. This space is lit by punchier LED lights, the luminous equivalent of a shot of espresso. Gather & Brew have grabbed the attention of Improper Bostonian, Boston Globe, Phantom Gourmet, and Metro.
Maryann Thompson Architect
Maryann Thompson
Martha Foss
AIA Awards,
Massachusetts Historical Commission Preservation Award
741 Mt. Auburn Street, Watertown, MA 02472
About Maryann Thompson Architect
Maryann Thompson Architect, a Cambridge-based design firm, is making a mark on the Boston foodie scene with restaurants in the pages of Boston Magazine, Bon Appetit, Improper Bostonian, Esquire, and The Boston Globe. Founder and Principal Thompson studied at Princeton University before obtaining Master of Architecture and Landscape Architecture from the Graduate School of Design at Harvard University. Martha Foss, AIA, also a principal, is an 11-year veteran of Maryann Thompson Architect, educated at the University of Virginia and Yale University School of Architecture. The team has earned three national American Institute of Architects awards, multiple honors from AIA chapters throughout the Northeast, and a Preservation Award from the Massachusetts Historical Commission.
Trade, named Best New Restaurant by Boston Magazine and Improper Bostonian, was designed by Maryann Thompson Architect in collaboration with Chef Jody Adams. The Downtown Boston restaurant takes advantage of some of the original architecture in the Russia Wharf high-rise, ground floor space. Steel, riveted columns got a coat of white paint, while the brick ceiling was sealed and whitewashed. Sculptural, white ceiling panels partially obscure the mechanical infrastructure and serve as a reflective counterpoint to the polished, amber, concrete floors. Oversized, hammered metal light fixtures and a custom, articulated mirror installation suffuse the restaurant with a deceptively simple and intimate glow. Bon Appetit Magazine named Trade one of their Top 50 Best New Restaurants. On the other side of the Charles River is Maryann Thompson Architect-designed Rialto. The Cambridge restaurant opens on a mosaic foyer. As diners make their way to the lounge, then through to the dining room, the way is occasionally interrupted by sheer panels, creating moments for appreciation of the rich mahogany floors, intimate banquettes, and backlit stone finishes. Mohair, suede, and glittering quartz invite touch, leading Esquire magazine to name Rialto one of the most romantic eateries in the U.S.
McMahon Architects
David McMahon
535 Albany Street, Suite 3F, Boston, MA 02118
About McMahon Architects
David McMahon, AIA and member of the National Council of Architectural Registration Boards (NCARB), earned as Master of Architecture from Yale University before working with prestigious design firms I.M. Pei and Partners and CBT Architects. In 1997, McMahon established his eponymous firm and has served as president and CEO for the last 20 years. Also at the helm of the firm's restaurant designs is Niemitz Design Group-veteran and McMahon Architects Director of Hospitality Neli Ialamov, who trained at the Massachusetts College of Art & Design. The team has had multiple dining projects land on the Boston Globe list of Boston's 50 Best New Restaurants — even holding down five locations ranked in the same year. Boston Business Journal, Eater Boston, Esquire have published writeups on some of McMahon Architects' top restaurants.
Architectural Digest profiled Townsman, a McMahon Architects-designed restaurant owned by James Beard Award nominee Matt Jennings. The Kingston street brasserie spans 4,500 square feet, from its spirited dining room to the granite-topped bar and outdoor patio. Deep, leather armchairs and a matte black ceiling are juxtaposed with floor-to-ceiling glazing and polished concrete floors. Up to 180 guests can enjoy a bite at a natural wood table, in the lounge, or seated at the crudo bar topped with butcher block. Most seats come with a view of the open kitchen. Tasting Counter — deemed Boston's Most Important Restaurant Opening by Zagat — is a more experimental foray into the open kitchen concept. All 20 seats in the untraditional dining room are arranged around a U-shaped countertop. In the center, Chef Peter Ungar and Chef Marcos Sanchez, prepare a multi-course meal. The restaurant is tucked into a corridor in Aeronaut Brewing Company, but it can't hide from the press. Boston Globe rated Tasting Counter three out of four stars and it was No. 1 on the Boston Magazine list of the Top 25 Best New Restaurants.
RODE Architects
Kevin Deabler, Eric Robinson
535 Albany Street #405, Boston, MA 02118
About RODE Architects
Kevin Deabler, AIA, LEED AP, and Eric Robinson, AIA, LEED AP, founded RODE Architects in 2005. The South End firm benefits from the pair's extensive experience in their fields. Deabler obtained degrees in architecture and environmental design from North Carolina State University's College of Design. Both worked with prominent, Boston-area architecture firms — CBT Architects and Charles Rose Architects, respectively — before partnering. Today they lead a team of close to 20 designers and staffers to produce architectural solutions for education, residential, and hospitality clients. Look for RODE Architects restaurant projects in articles published by Boston Business Journal, Dorchester Reporter, Boston Herald, Boston Magazine, and more local and national outlets.
RODE Architects brought to life the first solo restaurant of Boston legend, Top Chef contestant, and James Beard Foundation award winner, Chef Karen Akunowicz. The Fox & the Knife opened in 2018 at a narrow, deep space near the busy intersection of West Broadway and Dorchester Avenue, near the Broadway T stop. It aims to be a slice of summer in cold Boston with its deep blue walls, dark velvet upholstering, dark wood tabletops, high ceilings, and warm lights. Floor-to-ceiling Broadway-facing windows flood the space with natural light while a 6-seat bar looks into the kitchen, showcasing the meticulous preparation of artful dishes. The restaurant has been named one of the best new restaurants in America by Eater National, Food & Wine, and USA Today. In East Cambridge, just a block from the Longfellow Bridge, is RODE Architects-designed Commonwealth Restaurant & Market. The project comprises two main spaces: the 1,300-square-foot market and a 5,200-square-foot restaurant and bar that spill out to a patio. In both the dining room and shop you'll find the seasonal, farm-to-table fare that inspired the restaurant's finishes and architecture. Simple, wood pallets are elevated by careful arrangement as partitions around the private dining room, glowing in the warmth of backlighting and exposed brick. The copper-topped bar reflects light from industrial-style pendants and offsets the more rustic finishes.
Sousa Design Architects
Stephen A. Sousa
Boston Architectural College Alumni in Practice Award,
Boston Magazine Shooting Start Award
81 Boylston Street, 2nd Floor, Brookline, MA 02445
About Sousa Design Architects
Sousa Design Architects offers architectural, interior, and graphic design to clients across residential, hospitality, and commercial sectors. Founder and Principal Stephen A. Sousa, AIA, NCARB, graduated with an architecture degree from Boston Architectural College. In 1998, Sousa established his eponymous firm, and 20 years after he obtained his degree, his alma mater and his peers recognized him with an Alumni in Practice Award. Sousa and his team have sourced materials from all over the world to create a distinctive portfolio of nearly 200 restaurant projects. Many of those restaurants have captured the attention of Boston Magazine, Boston Globe Magazine, Wallpaper, and Hospitality Design.
Joe's American Bar & Grill has a number of locations in the Boston area, but the Newbury Street spot in Back Bay has a feature that sets it apart from the others — and every other eatery in Boston. Sousa Design Architects converted the existing greenhouse of the 30-year-old Joe's into an all-weather patio topped with a retractable roof. The restaurant used to open to the sidewalk via folding, glass doors, but the new design allows diners to enjoy an al fresco experience without the restaurant sacrificing room for more diners. Hailed by Boston Magazine as 2018's Best Southeast Asian Restaurant, Tiger Mama is a culinary adventure headed by James Beard Foundation Award winner Tiffany Faison. Sousa Design Architects headed the architecture and interior design of this one-of-a-kind restaurant. The firm took the challenge of turning a previously difficult space for a restaurant into a bustling hub of Southeast Asian cuisine and design. Ash-wood chandeliers installed in the dining room were inspired by baskets of rice and fish while an ever-changing living wall of herbs, succulents, and palm fronds make for a perfect backdrop for bright orange accents and a disco elephant. For this eclectic yet comfortable mix, Tiger Mama took home a Restaurant Design of the Year from Eater Boston.
studioTYAK
Stephen Martyak
Zagat Boston Hottest Up and Comers
236 Huntington Avenue, Suite 216, Boston, MA 02115
About studioTYAK
studioTYAK is an entertainment-focused architecture firm designing eye-catching Boston restaurants and venues. Founder and Principal Stephen Martyak — the first designer to land on the Zagat 30 Under 30 list of Boston's Hottest Up-and-Comers — studied design at Boston Architectural College before going on to receive his Master of Architecture from Savannah College of Art & Design. As director of design for Tribeca Builders in Boston, Martyak rounded his knowledge base. He established studioTYAK in 2012, and in just five years, the firm's portfolio has drawn notice from Design New England, Boston Magazine and Eater. Martyak is also a founding member of Design Museum Boston and an associate member of the Boston Society of Architects.
Boston Chops subverts the typical steakhouse aesthetic with a design that draws on its South End surroundings. Thrillist named the eatery "one of the Best Designed Restaurants in America," for its sensual and urbanized decor. Throughout the richly appointed bistro, shining chrome and blackened steel accents balance the natural textures of slate tile walls and reclaimed oak panels. The 40-foot bar is wrapped in deep green tiles and topped with butcher block. For Southern food spot Loretta's Last Call, studioTYAK designed an environment that would transport diners from the Fenway to Nashville. A native of the South himself, Martyak drew on his own experiences to design Boston's first country music bar. Live performances take place in front of a patterned, wood backdrop, emblazoned with the restaurant's namesake and surrounded by marquee lights. Guests can take in the show at a table under the red-painted, coffered ceiling, or sit at a bar constructed from reclaimed wood with more than 150 years of history.
Studio Luz Architects
Hansy L. Better Barraza
Anthony J. Piermarini
Architectural League of New York Young Architect's Award,
Architectural Record Design Vanguard Award,
Hospitality Design Magazine Wave of the Future Award
67 Poplar Street, Boston, MA 02131
About Studio Luz Architects
Principals and founders Hansy L. Better Barraza, AIA, LEED AP, and Anthony J. Piermarini, AIA, founded Studio Luz in 2002. Barraza and Piermarini both earned Master of Architecture degrees from Harvard Design School before partnering to form an Architectural Record Design Vanguard Award-winning firm. Over the last 15 years, the company has earned the Wave of the Future Award from Hospitality Design magazine, an Architectural League of New York Young Architect's Award, and numerous other industry awards and nominations.
For Diva Lounge in Somerville, Studio Luz created a space that not only set the mood, but also responded to it. In this setting, the earthy bar top, carved from a full log, reads as otherworldly. Banquettes carved from the salvaged material from a disease-ravaged, Vermont butternut serve as textural counterpoints to walls wrapped in convex, plastic panels and low-voltage LEDs. The design earned an Interior Architecture Award from Boston Society of Architects, Best Designed Hospitality from DDI Magazine, and the Illumination Design Award from The Illuminating Engineering Society of North America. The Improper Bostonian reported on the Studio Luz-designed Harpoon Brewery visitor's center — a new South Boston beer hall and retail outlet for brewery visitors. The space can be divided into a public hall and private event room by lowering a large, bi-fold door. The finishes speak to Harpoon's New England pedigree. Bars and tables are topped with live-edge Vermont butternut, while the floors are made from reclaimed oak planks. The environment also lets visitors in on the many processes that go into crafting beer. Exposed pipework, storage vats, and bottling lines galvanize the insider experience for those taking a tour and for guests just enjoying a drink at the main bar, or filling a growler at an array of taps.
Whitlock Design Group
681 Main Street, Suite 3-31, Waltham, MA 02451
About Whitlock Design Group
Bill Whitlock started Whitlock Design Group in 2000 after working for a couple of firms straight out of Cornell University. He previously sat as both AIA representative for New England for the Small Firms Roundtable and BSA Chairperson for the Small Firms Network. His firm is now a leader in restaurant and hospitality design with an extensive portfolio of dynamic and innovative retail, restaurant, and entertainment venues. He serves as the New England representative to the American Institute of Architects Small Firm Round Table and chair of the Small Practices Network of the Boston Society of Architects. The firm's work has been covered by Boston Magazine, Eater Boston, The New York Times, and GQ.
Whitlock Design Group is behind the massive new multi-level restaurant and brewery of Trillium Brewing Company in Fort Point. Located at a Boston Wharf warehouse, its design tells the story of Boston's early rise as a prominent industrial city through its timber structure and brick walls. The space uses a palette of wood, concrete, and blackened steel. The first floor features a beer hall, a brewery, and a retail space that is designed with a large glazed wall behind its prominent bar that showcases stainless tanks and wooden Foeder tanks. The second floor is a warm restaurant space that plays with brick and wood. The project has been featured by Eater Boston and Boston Magazine. Whitlock Design Group worked on famed Irish pub MJ O'Connor's Boston Park Plaza location. Centered between beautiful groin vaulted ceilings, the space is anchored by a large island bar topped with Carrera marble and a mahogany base with floating glass shelves and beer taps. Whimsical artwork and chandeliers enhance the arched ceilings and pay homage to the restaurant's Irish heritage.
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Advances Are Being Made in Diagnostic Testing for Early Lyme Disease
Experts from academia, industry, and public health agencies—including the Centers for Disease Control and Prevention and the US Food and Drug Administration—discuss the new generation of antibody tests.
One of the biggest challenges individuals with Lyme disease face is getting a correct, timely diagnosis of their illness. The problem is the diagnostic tests that are currently available, along with the current standard testing protocol, are a little outdated.
To discuss the pros and cons of the current diagnostic tests available for Lyme disease, members from academia, industry, and public health agencies—including some from the Centers for Disease Control and Prevention (CDC) and the US Food and Drug Administration (FDA)—convened at a Cold Spring Harbor Laboratory Banbury conference. The meeting was so fruitful that they decided to develop an article on the discussions, which was published today in the journal Clinical Infectious Diseases.
"Currently the standard for laboratory diagnosis of Lyme disease is primarily based on the demonstration of antibodies against Borrelia burgdorferi (B. burgdorferi), the causative bacteria," senior author Steven Schutzer, MD, a physician-scientist at Rutgers New Jersey Medical School told Contagion® in an interview. "The testing paradigm, a 2-tiered protocol, consists of a sensitive first test, usually an enzyme immunoassay (EIA) that, if positive or borderline, is followed by a second assay, a Western immunoblot to increase specificity."
Although this approach has become standard when it comes to Lyme disease diagnosis, it is not without its drawbacks; this is not surprising, as the paradigm was established in 1994. "Over ensuing years various shortcomings became apparent as new information was discovered," Dr. Schutzer explained. "It was already known that it is insensitive in early weeks of the infection, and the interpretation of the Western blot has proven to be confusing to many doctors (blots are most often visually read by a person, rather than by a machine)."
This confusion is because when the Western blot criteria were formulated, "it was not known that some key proteins of the Lyme agent were only produced during an actual infection and these proteins were left out of the criteria," Dr. Schutzer noted. The other problem is that there are some proteins that had been included in the criteria that are similar to proteins found in other bacteria. "These 'cross-reactive' proteins can bind antibodies produced against infections other than Lyme disease," Dr. Schutzer explained. These issues with sensitivity and specificity have made interpretation of results challenging.
Luckily, a new generation of antibody tests has emerged, according to the authors of the article. One is a single multiplex assay with synthetic targets and another is a combination of EIAs. The next-generation EIAs, when compared with the commonly used EIAs that are prepared from whole-cell sonicates (WCS) of cultured B. burgdorferi bacteria (WCS EIA), are more specific, and, as such, it has been suggested that they be used without a supplemental second-tier assay. Two large studies have been conducted to compare the specificity of next-generation EIA tests with the current 2-tiered testing paradigm (using WCS EIA followed by Western blot).
An approach to serologic testing suggested performing 2 EIAs sequentially in a 2-step process or simultaneously without a Western blot. The paper authors write that many investigators have examined the use of a "2-EIA" testing protocol—using the WCS EIA and the C6 EIA in a 2-tiered testing paradigm. "When these 2 tests are applied in 2-tiered testing, specificity is greater than that of either test alone and is equal to the specificity of standard 2-tiered testing with EIA and immunoblotting," the authors write. Furthermore, research has shown that this approach can be more sensitive than the standard 2-tiered testing commonly used today.
The 2-EIA protocol shows several benefits over the standard testing protocol, according to the article:
Results are straightforward (the patient is seropositive or seronegative) and objectively obtained via an instrument system.
It may be more cost-effective than protocols that call for immunoblotting.
The methodology is more easily accessible to most clinical laboratories, which can decrease turnaround time to yield results.
The other testing platform consists of a single multiplex test "designed to provide information about antibody responses to multiple Borrelia antigens, including bead-based assays or microchip configurations," the authors write. "This approach offers the prospect of a single-tier assay in the near future and lends itself to adaptations as new data are discovered."
The authors reference a study that supports the single multiplex concept which used epitope mapping of key B. burgdorferi antigen targets from both in vivo and in vitro expressed antigens. They noted that "peptides containing specific epitopes, with or without recombinant antigens, are uniquely suited as antigen targets in multiplex platforms." As an example, one bead-based assay included 10 separate antigens, some of which comprised epitopes that were more specific than those found in the Western blots using the 1994 Dearborn criteria. In that evaluation, the antigen panel was more sensitive in early Lyme disease than the standard 2-tiered algorithm while maintaining high specificity.
Although advances made in testing approaches are helpful, Dr. Schutzer stressed that laboratory tests are adjunctive tools that should be used in tandem with patient evaluation by health care providers.
"The earlier you can make a diagnosis, the earlier you can give rational treatment, and that's your best chance for curing and simultaneously preventing long-term neurological, cardiac, or joint problems," Dr. Schutzer stressed.
The article, "Advances in serodiagnostic testing for Lyme disease are at hand," was published online early on December 7, 2017, in Clinical Infectious Diseases. DOI: 10.1093/cid/cix943.


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When you see a Stork on Yoshi's Island….
A Tribute to Super Mario World 2: Yoshi's Island by Keith Byrne
The Super Mario Bros. game series is over 30 years old now and full of excellent games that represent the evolution of platformer games through all the years.
Super Mario World 2: Yoshi's Island was no exception but it was also one of the relative few Super Mario games that fully utilized the power of the current hardware. In Yoshi's Island case it even needed a special chip to make something like the fluid animations, 3D effects and giant enemies possible. It is no wonder that it is one of the most remembered games of the 16 bit era.
Beside being one of the most beautiful games on Nintendo 16bit system it is also one of the cutest Mario game and introduced baby versions of known characters like Mario, Luigi and even a very young Bowser. It is not sure where Bowser is from, but at least the Italian plumbers were brought to us by a Stork..who was just flying over Yoshi's Island when something bad happened which would change the fate of the Mushroom Kingdom many years later!
Kudos go to Keith Byrne from Ireland who draws his favourite video games since many years and is actually one of the many artists that participated in our Pokemon Generation II Tribute that is getting unleashed on the 16th September here.
I recommend to have a look at the many works by Keith here!


Mobile computing for the ski industry.
As a long time NSAA member and industry supplier, over 75 ski and resort customers rely on our experienced team and innovative solutions to solve a wide range of resort and ski area business challenges.
This year at NSAA National Convention & Tradeshow, ExtenData will focus on our Top 3 RFID Solutions for the Ski Resort Industry. Learn more about each solution.
If you are looking for a qualify pass scanning solution without the high cost and limitations of RIFD gates, we've got a solution for you.
Using UHF RFID readers from Zebra Technologies, ExtenData can help you avoid the challenges that RFID gates present.
Media/pass supplies are more cost effective, reusable, and are not proprietary based on the RIFD device like gate technology.
Without gates, mobile devices allow scanning distances is increased to 5-10ft.
Without gates, there is no seasonal setup and tear down of gates. Simply store your UHF RFID devices in a safe place.
The cost of media can become overwhelming for ski operations, especially if a resort is using HR RFID proprietary printers and cards.
Why not have a card printing solution that allows your resort to tie multiple revenue generating centers into one easy to use card for your guests?
Looking to print Non RFID Passes? We'd recommend the Zebra Series 3 Card Printers. Send us a quick message and we'll be happy to send you a quote today.


It's not uncommon to find superstitions in cultures around the world. In the United States, some people believe that you should carry a good luck charm and you should avoid black cats. In China, the number 8 (eight) is lucky, and the number 4 (four) is unlucky. In Russia, you should never hand money directly to another person, and you should only use your right hand.
It's hard to know how or why any superstitions were created, but millions of people are dependent on them and believe they are powerful. It can be comforting to feel that there's a reason that a bad event has happened in your life, and also comforting to feel that you can stop more bad events from happening if you pay attention to superstitions.
Are Lily and Marni superstitious? Find out in today's English lesson.
Lily: Marni, is that a rabbit's foot?
Lily: So, I take it you're superstitious.
Marni: I am so superstitious. I have to have good luck charms on me at all times or I believe bad things will happen to me!
Lily: That must be kind of scary to be dependent on inanimate objects like that.
Lily: Definitely don't break a mirror!
Marni: Exactly. I really think that if you heed certain things, that good things will happen.
Lily: So, how did these superstitions come about? Did you just decide to become superstitious one day?
Marni: Oh, no. It's been passed down in my family, so I've always been very aware of it.
Marni and her family are superstitious. She carries good luck charms, for example, and she's careful to avoid doing things that will bring her bad luck.
It doesn't seem like Lily believes in the same superstitions, but she doesn't make fun of Marni. It's quite common for people to share the same beliefs, and it's not like Lily hasn't learned them, too.
Are you superstitious? What do you believe will give you good or bad luck?
I'm least superstitious. But I feel that if I don't treat weak and poor gently it will bring curse on me. I believe kindness and civility bring good luck.
However, I think if someone believe on superstitions, it do work on them; not because of lucky charms or unlucky objects but because they subconsciously react to it accordingly. For instance, if black cat is unlucky object for some people, it will make them scared and this will lead them to clumsy situations.
To be honest i amn't very much into superstitious things. but sometimes it becomes very hard not to believe or to follow as people around you following that. you might not be following right now but whenever you have a hard time you try to do each and everything to get you good luck back.
here in india i have always been told not to cut off nails on thursday, not to wash clothes on thursday, not to eat non veg on tuesday etc etc.
i believe everything is in your mind now its upto you. i am neither in favor of this nor against it.
In my country it is were common to belive and heed in such an inamate object,you cant imagine even worst it is a thought that you should not cat you nailns on Tuesday evening,next dont pass the same round when cats walk,or turn back three steps after cats pasing road.The old generation feel very comfort attending their opinion and advise young people to heed and arm onself the think they could prevnt beliving on superstitions and in this way by telling different stories to make them dependent.
Superstitions connect us with ancient time and even now they are still powerfull, and impact on our behaviour.I remember coming to visit my friend and suddenly a bird flew in. After we turned it out,my friend became sad, as she thought that it was a bad sign to her. I think, all this beliefs are so much deep in our conscience, that it is difficult to get rid from them at the moment. Logically I know, that it is an absurdity to search for any connection among a black cat, crossing a road in front of you in the morning, and your failures in the evening, but in fact I feel myself a bit uneasy when see it on my way.By the way, I used to think that to see a black cat was a bad sign only in Europe, but from the lesson it is clear now, that this kind of superstition is spreaded more widely.
There is a great numer of different superstitions in my country for getting luck, money, happyness, grief, leaving and so on. All our wishes and fears are reflected there.
However, I dont consider superstitions to be absolutely negative, as they add some mystery in our life and make it not so much rational.
Well. Certainly, there are some superstitious thoughts in my local culture however i've never believed them at all. It's hard to accept things without making sense tome. Generallyspekaing , I should say i'm not superstitious boy .
One of incredible believes is to see a cat in the morning. People with this attitude thing that sth will go wrong with them and they will be inbig trouble if it happen to them. I saw some cats at twilight and even black ones though, but it was a normal day to me like other days. It's weird, han.
It's not usual in here to use good luck charms although rarely a few guys use some kinds of necklace to protect them. That's odd. The truth is that most of the possible events are based on probabilistic theories like probability laws in the statistic science.
just try to read " Law of Attraction"and "The Secret" then u come to believe in superstitions; thinking and (believing) in good things bring u good luck.
I don't believe in any superstitious influnces, it is over good and bad deeds that comes in different faces some time good and some time in wicked shape.
I don't trust superstitius things, I am not superstitius at all.
i think, its up to God if some event happens or dont..if you are lucky or not..and etc.
Superstition is just people's imagination, in my opinion!
I am sometimes superstitious. When my right eye winks good things happen to me.
I have never think of superstitions. I only believe in Allah. and think of real things, and work hard to achieve my goals.
I believe if one need a great success, he/she must need lucks or a big luck. Being heavily spurestitious seems to be uneccessary.I am a litte suprestitous about how a couple go through an obsatckle . I belive it is a good luck they go through it in the same dirction whether it is right or left, as long as they don't go seperate ways which is a symbolism of seperation or the end of a relationship .
I think luck is sth which is true for every one but being superstitious is sth different!
I'm not superstitius and i don't believe in things like black cat or other things!
I don't Believe in Luck . I only believe in God .


text:
Real Madrid Legends Praise Anfield Atmosphere
Luis Figo, Clarence Seedorf among former Madrid stars to talk up the home of their opposition
By Bridget Gordon@thaumatropia Mar 26, 2017, 3:00am BST
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Liverpool Legends hosted Real Madrid Legends at Anfield earlier today as a fundraiser for the LFC Foundation. The match ended in a 4-3 win for the home side and some good-natured revenge for their loss two years earlier. But more to the point, the game raised money for a good cause and also served as a platform for more touching tributes for the late Ronnie Moran.
After the match, a few members of the Madrid side spoke to the press, and one theme kept coming up— the special atmosphere at Anfield.
Some choice quotes from the presser:
Luis Figo: "It's always amazing to play in stadiums like Anfield with this atmosphere, even when it's for a charity game and a fantastic cause."
Clarence Seedorf: "I absolutely enjoyed it from the first to the last minute."
Leo Beenhakker: "Everywhere plays football, but there are some places in Europe that are very special and magic. Every time I see matches in this stadium it's great to see the crowd and fantastic."
Figo: "We tried to enjoy it as much as possible. It's not easy for me to come back and play a game after six months without playing or training properly."
Seedorf: "The most important thing is to entertain people as much as we can. Seven goals and in the last minutes a bit of tension, it was all good."
Beenhakker: "[Anfield]'s very famous in Holland, and every time the whole stadium starts singing You'll Never Walk Alone, it's fantastic to see."
Figo: "What I do now is exercise that is nothing compared to what you need for football!"
Seedorf: "It's a great cause and participating in these kind of games is fantastic. I'm not the first and I won't be the last to say that Anfield is absolutely amazing."
Beenhakker: "On one side, it's still important because we are all really still professionals and even if you are 40 or 50 or in my situation some years more, you always want to win. You hate to lose. That's the spirit of the game. It's amazing to see these guys playing at this age to do everything to win the game. It makes me a little bit emotional when I do these matches."
This was fun! Can we do this every year?


Home » Portfolios » 2018 Commercial Vehicle Show – Royal Mail LDV wrap live!
It was great to attend the Commercial Vehicle Show this year and great to see our live wrapping demonstration appearing in the show highlights video. And what better than Fleet Director for Royal Mail, Paul Gatti, unveiling the newly wrapped LDV van at the CV Show in front of an audience!
Completing this vehicle wrap at the Commercial Vehicle Show really demonstrates the team effort which GK Signs puts into every project we do. It was great to meet everyone there and we really enjoyed the live demonstrations.


Housed in a historical building, this hotel is ideally located in the heart of Mont Saint-Michel. The classic-style rooms overlook the bay, the abbey or the medieval city. All rooms at the La Mère Poulard are equipped with a flat-screen TV and free Wi-Fi access. The private bathrooms are fitted with a bathtub. Guests are invited to sample La Mère Poulard's recipes, including the worldwide-famous omelette, in the prestigious restaurant. A drink can be enjoyed in the piano bar, overlooking the Bay of the Mont Saint Michel. The hotel has a shop selling regional gourmet products. The front desk is open 24 hours a day. Activities include cycling and hiking and visiting the Mont Saint-Michel. Avranches is a 23-minute drive away. Saint-Malo is 45 minutes from La Mère Poulard.
Please note that beverages are not included in the Special Offer.
Please note that due to the island nature of Mont Saint-Michel, the WiFi network quality may be variable.
This hotel does not have a lift.
Breakfast in served between 08:00 and 10:00.
Please note that in the twin rooms it is possible to put the 2 beds together.
Please note that the nearest parking is 2 km far from the property. Guests can take a shuttle then will have a 500-metre walk to reach the Hotel on Mont Saint-Michel.
Please note that the access to the area by car is subject to a surcharge. Access to the property's car park costs EUR 12 for a one-time entrance. Payment will be made on an electronic payment terminal, upon departure.
Groups : When booking for more than 14 persons, different policies and additional supplements may apply.
Parking : Public parking is possible at a location nearby (reservation is needed) and costs EUR 14 per day.


I can sense the growing interest of people from Malaysia to travel to my home country, the Philippines. Perhaps it's because of the increasingly growing economy (thanks to the new President, which I hope will deliver more than the previous ones). Or perhaps the increasing coverage of its islands like Boracay and Palawan. Maybe because of its campaign called "More Fun In the Philippines"?
Anyway, whatever the reasons are, the cheapest way to get to Manila is via Cebu Pacific. I am aware that there is the Air Asia option, however, unless Air Asia starts flying directly into NAIA (the airport at the heart of Manila), I will never take that route. Air Asia currently lands directly into Clark, which is a pain, if you want to get to Manila. Did I mention the hell traffic in Manila, you wouldn't want to get caught up in that!
Meanwhile, I wanted to share a little piece of information. If you plan your trip well, you could get cheap tickets to Manila via Cebu Pacific airline. In my experience for the past 6 years living in KL, this has been an "okay" airline delivering decent service at a good price.
I received a notification on their seat sale, which can get very, very interesting.
Another option is to take Malaysian Airlines or Philippine Airlines. Though most of the time it can be pricey. I heard from a friend that occasionally they do seat sales, but not as often as Cebu Pacific.


text:
Behind the Prizes: Hers to Lose
Brent McDonald was the lead videographer for the New York Times' 'Hers to Lose,' the second-prize long feature winner in the 2014 World Press Photo Multimedia awards. McDonald explains the challenges of filming a campaign that took a turn for the worse, and how he and his team got access in the first place.
by Joanna Plucinska on February 2, 2015
Categories: In the field • Tags: brent mcdonald, documentary, Hers to Lose, new york times, new york times video, world press, World Press Photo Multimedia Award
Covering Protest in Ferguson: "These are people, not sound bites."
Brent McDonald is a senior video journalist with the New York Times. He produced "Standoff in Ferguson," a three-minute video for the Times that was published on August 14th, in the midst of protests over the police shooting of 18-year-old Michael Brown.
McDonald has been producing video for over ten years, and has been with the Times since 2005. Columbia Visuals spoke with him by phone from Ferguson, Missouri, on August 15th. He told us about the mood there and gave us some details on his production methods. (more…)
by Abbey Adkison on August 16, 2014
Categories: In the field • Tags: 5d mark III, brent mcdonald, canon 5d, documentary video, ferguson, ferguson missouri, ferguson protests, new york times, new york times video, police, protest, protests, sennheiser, video


text:
Research Capital Region of Denmark Amager Hospital Bispebjerg Hospital Bornholms Hospital Frederiksberg Hospital Frederikssund Hospital Gentofte Hospital Glostrup Hospital Helsingør Hospital Herlev Hospital Hillerød Hospital Hvidovre Hospital Region Hovedstadens Psykiatri Rigshospitalet
Hospitals/Units Find departments and units at Region H
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The Capital Region of Denmark
Distance to invasive heart cen...
Citationformats
The Capital Region of Denmark - a part of Copenhagen University Hospital
Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study
Tranberg, T, Lippert, FK, Christensen, EF, Stengaard, C, Hjort, J, Lassen, JF, Petersen, F, Jensen, JS, Bäck, C, Jensen, LO, Ravkilde, J, Bøtker, HE & Terkelsen, CJ 2017, 'Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study', European Heart Journal (Online), vol. 38, no. 21, pp. 1645. https://doi.org/10.1093/eurheartj/ehx104
Tranberg, T., Lippert, F. K., Christensen, E. F., Stengaard, C., Hjort, J., Lassen, J. F., Petersen, F., Jensen, J. S., Bäck, C., Jensen, L. O., Ravkilde, J., Bøtker, H. E., & Terkelsen, C. J. (2017). Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study. European Heart Journal (Online), 38(21), 1645. https://doi.org/10.1093/eurheartj/ehx104
Tranberg T, Lippert FK, Christensen EF, Stengaard C, Hjort J, Lassen JF, Petersen F, Jensen JS, Bäck C, Jensen LO, Ravkilde J, Bøtker HE, Terkelsen CJ. 2017. Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study. European Heart Journal (Online). 38(21):1645. https://doi.org/10.1093/eurheartj/ehx104
Tranberg, Tinne et al. "Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study". European Heart Journal (Online). 2017, 38(21). 1645. https://doi.org/10.1093/eurheartj/ehx104
Tranberg T, Lippert FK, Christensen EF, Stengaard C, Hjort J, Lassen JF et al. Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study. European Heart Journal (Online). 2017 Mar 29;38(21):1645. https://doi.org/10.1093/eurheartj/ehx104
Tranberg, Tinne ; Lippert, Freddy K ; Christensen, Erika Frischknecht ; Stengaard, Carsten ; Hjort, Jakob ; Lassen, Jens Flensted ; Petersen, Frants ; Jensen, Jan Skov ; Bäck, Caroline ; Jensen, Lisette Okkels ; Ravkilde, Jan ; Bøtker, Hans Erik ; Terkelsen, Christian Juhl. / Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest : a nationwide study. In: European Heart Journal (Online). 2017 ; Vol. 38, No. 21. pp. 1645.
@article{b96ddda8f0114f9d8c9a27f45947bddd,
title = "Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest: a nationwide study",
abstract = "Aims: To evaluate whether the distance from the site of event to an invasive heart centre, acute coronary angiography (CAG)/percutaneous coronary intervention (PCI) and hospital-level of care (invasive heart centre vs. local hospital) is associated with survival in out-of-hospital cardiac arrest (OHCA) patients.Methods and results: Nationwide historical follow-up study of 41 186 unselected OHCA patients, in whom resuscitation was attempted between 2001 and 2013, identified through the Danish Cardiac Arrest Registry. We observed an increase in the proportion of patients receiving bystander CPR (18% in 2001, 60% in 2013, P < 0.001), achieving return of spontaneous circulation (ROSC) (10% in 2001, 29% in 2013, P < 0.001) and being admitted directly to an invasive centre (26% in 2001, 45% in 2013, P < 0.001). Simultaneously, 30-day survival rose from 5% in 2001 to 12% in 2013, P < 0.001. Among patients achieving ROSC, a larger proportion underwent acute CAG/PCI (5% in 2001, 27% in 2013, P < 0.001). The proportion of patients undergoing acute CAG/PCI annually in each region was defined as the CAG/PCI index. The following variables were associated with lower mortality in multivariable analyses: direct admission to invasive heart centre (HR 0.91, 95% CI: 0.89-0.93), CAG/PCI index (HR 0.33, 95% CI: 0.25-0.45), population density above 2000 per square kilometre (HR 0.94, 95% CI: 0.89-0.98), bystander CPR (HR 0.97, 95% CI: 0.95-0.99) and witnessed OHCA (HR 0.87, 95% CI: 0.85-0.89), whereas distance to the nearest invasive centre was not associated with survival.Conclusion: Admission to an invasive heart centre and regional performance of acute CAG/PCI were associated with improved survival in OHCA patients, whereas distance to the invasive centre was not. These results support a centralized strategy for immediate post-resuscitation care in OHCA patients.",
author = "Tinne Tranberg and Lippert, {Freddy K} and Christensen, {Erika Frischknecht} and Carsten Stengaard and Jakob Hjort and Lassen, {Jens Flensted} and Frants Petersen and Jensen, {Jan Skov} and Caroline B{\"a}ck and Jensen, {Lisette Okkels} and Jan Ravkilde and B{\o}tker, {Hans Erik} and Terkelsen, {Christian Juhl}",
doi = "10.1093/eurheartj/ehx104",
pages = "1645",
journal = "European Heart Journal (Online)",
T1 - Distance to invasive heart centre, performance of acute coronary angiography, and angioplasty and associated outcome in out-of-hospital cardiac arrest
T2 - a nationwide study
AU - Tranberg, Tinne
AU - Lippert, Freddy K
AU - Christensen, Erika Frischknecht
AU - Stengaard, Carsten
AU - Hjort, Jakob
AU - Lassen, Jens Flensted
AU - Petersen, Frants
AU - Jensen, Jan Skov
AU - Bäck, Caroline
AU - Jensen, Lisette Okkels
AU - Ravkilde, Jan
AU - Bøtker, Hans Erik
AU - Terkelsen, Christian Juhl
N2 - Aims: To evaluate whether the distance from the site of event to an invasive heart centre, acute coronary angiography (CAG)/percutaneous coronary intervention (PCI) and hospital-level of care (invasive heart centre vs. local hospital) is associated with survival in out-of-hospital cardiac arrest (OHCA) patients.Methods and results: Nationwide historical follow-up study of 41 186 unselected OHCA patients, in whom resuscitation was attempted between 2001 and 2013, identified through the Danish Cardiac Arrest Registry. We observed an increase in the proportion of patients receiving bystander CPR (18% in 2001, 60% in 2013, P < 0.001), achieving return of spontaneous circulation (ROSC) (10% in 2001, 29% in 2013, P < 0.001) and being admitted directly to an invasive centre (26% in 2001, 45% in 2013, P < 0.001). Simultaneously, 30-day survival rose from 5% in 2001 to 12% in 2013, P < 0.001. Among patients achieving ROSC, a larger proportion underwent acute CAG/PCI (5% in 2001, 27% in 2013, P < 0.001). The proportion of patients undergoing acute CAG/PCI annually in each region was defined as the CAG/PCI index. The following variables were associated with lower mortality in multivariable analyses: direct admission to invasive heart centre (HR 0.91, 95% CI: 0.89-0.93), CAG/PCI index (HR 0.33, 95% CI: 0.25-0.45), population density above 2000 per square kilometre (HR 0.94, 95% CI: 0.89-0.98), bystander CPR (HR 0.97, 95% CI: 0.95-0.99) and witnessed OHCA (HR 0.87, 95% CI: 0.85-0.89), whereas distance to the nearest invasive centre was not associated with survival.Conclusion: Admission to an invasive heart centre and regional performance of acute CAG/PCI were associated with improved survival in OHCA patients, whereas distance to the invasive centre was not. These results support a centralized strategy for immediate post-resuscitation care in OHCA patients.
AB - Aims: To evaluate whether the distance from the site of event to an invasive heart centre, acute coronary angiography (CAG)/percutaneous coronary intervention (PCI) and hospital-level of care (invasive heart centre vs. local hospital) is associated with survival in out-of-hospital cardiac arrest (OHCA) patients.Methods and results: Nationwide historical follow-up study of 41 186 unselected OHCA patients, in whom resuscitation was attempted between 2001 and 2013, identified through the Danish Cardiac Arrest Registry. We observed an increase in the proportion of patients receiving bystander CPR (18% in 2001, 60% in 2013, P < 0.001), achieving return of spontaneous circulation (ROSC) (10% in 2001, 29% in 2013, P < 0.001) and being admitted directly to an invasive centre (26% in 2001, 45% in 2013, P < 0.001). Simultaneously, 30-day survival rose from 5% in 2001 to 12% in 2013, P < 0.001. Among patients achieving ROSC, a larger proportion underwent acute CAG/PCI (5% in 2001, 27% in 2013, P < 0.001). The proportion of patients undergoing acute CAG/PCI annually in each region was defined as the CAG/PCI index. The following variables were associated with lower mortality in multivariable analyses: direct admission to invasive heart centre (HR 0.91, 95% CI: 0.89-0.93), CAG/PCI index (HR 0.33, 95% CI: 0.25-0.45), population density above 2000 per square kilometre (HR 0.94, 95% CI: 0.89-0.98), bystander CPR (HR 0.97, 95% CI: 0.95-0.99) and witnessed OHCA (HR 0.87, 95% CI: 0.85-0.89), whereas distance to the nearest invasive centre was not associated with survival.Conclusion: Admission to an invasive heart centre and regional performance of acute CAG/PCI were associated with improved survival in OHCA patients, whereas distance to the invasive centre was not. These results support a centralized strategy for immediate post-resuscitation care in OHCA patients.
U2 - 10.1093/eurheartj/ehx104
DO - 10.1093/eurheartj/ehx104
JO - European Heart Journal (Online)
JF - European Heart Journal (Online)
Kongens Vænge 2
pure@regionh.dk
About Pure


text:
Mathieu Riebel (Sarcelles, 2 januari 1997 – Païta, 20 oktober 2017) was een Frans baanwielrenner.

Carrière
Als junior werd Riebel in 2014 tweede in zowel de puntenkoers als, samen met Guillaume Millasseau, in de ploegkoers tijdens de nationale kampioenschappen. Een jaar later won hij, wederom samen met Millasseau, de ploegkoers wel. Daarnaast won hij in 2015 de puntenkoers in Saint-Denis.

In 2016 werd Riebel, samen met Jordan Levasseur, Benjamin Thomas en Flavien Dassonville, derde in de ploegenachtervolging tijdens de nationale kampioenschappen voor eliterenners.

In 2017 nam Riebel op de weg deel aan de Ronde van Nieuw-Caledonië. In de negende etappe, tijdens de afdaling van de Col de la Pirogue, botste hij tegen de voorruit van een ambulance, waarna hij overleed.

Palmares

Frans baanwielrenner

redpajama_set_name: RedPajamaWikipedia


text:
Baker City soldier Spc. Mabry Anders remembered as 'bubbly, fun kid'
By Richard Cockle, The Oregonian
View full sizeDepartment of DefenseSpc. Mabry J. Anders was killed Monday in Afghanistan.
BAKER CITY -- Mabry James Anders, who died Monday of injuries from enemy small arms fire in Kalagush, Afghanistan, was a "bubbly, fun kid," a Baker High School administrator recalled Tuesday.
Spc. Anders, 21, the son of Troy and Genevieve Woydziak of Baker City, joined the Army on Jan. 5, 2010, and was deployed to Afghanistan this past March 10. He worked as a wheeled vehicle mechanic.
Farewell to the Fallen
a tribute to U.S. service members with Oregon and Southwest Washington ties
who died in Iraq and Afghanistan conflicts.
"He was a very likeable, social kid. He had an upbeat personality," said Baker High Assistant Principal Gundula O'Neal.
Anders' parents said they were proud of their son and his service to the nation. "Mabry always gave his all, and in the end he gave all he had," they said in a prepared statement. "We will miss his fearless spirit and love of life."
Anders was the 155th member of the military from Oregon and Southwest Washington to die in the wars in Afghanistan and Iraq.
Born in Yuma, Ariz., on July 22, 1991, Anders will be posthumously awarded the Bronze Star, Purple Heart, Combat Action Badge and NATO Medal, in addition to the National Defense Service Medal, Afghanistan Campaign Medal, Global War on Terrorism Service Medal and other awards, the army reported.
He left Baker High School before his senior year ended and transferred to the identically named Baker High School in the San Bernadino County town of Baker, Calif.
Also killed in the action that took Anders' life was Sgt. Christopher J. Birdwell, 25, of Windsor, Colo. They were assigned to the 4th Special Troops Battalion, 4th Brigade Combat Team, 4th Infantry Division at Fort Carson, Colo.
Richard Cockle


An extensive list of architects and architectural firms were involved in this long-term and complex addition at Westover Church in Greensboro. Architect Barry Parks played a lead role in two parts of this work. While at one firm, he authored the initial master plan for this work. The initial plan scope included a 2,300-seat sanctuary, numerous classrooms, and associated support spaces, placed in relationship to the existing campus facilities. After Parks left that firm to begin Trinity Architecture & Planning, the master plan was modified as the scope grew to 2,800 seats and design development work continued with a new designer. Five years later, Parks was called on to assist with the project again.
Focusing only on the worship space within the building shell, he was responsible for coordination with work of technical consultants, including theatrical lighting, curtains, video, sound, acoustically-treated air handling equipment, etc. Parks was responsible for creating the construction drawings for the sanctuary, with special emphasis on redesign of the stage and stage-support areas, balconies and balcony access, and ceiling/catwalk systems. The project cost was $28M.
Role: Master planning at ARCHITECTURAL DESIGN ASSOCIATES, followed with technical assistance and construction documentation under contract with BRADLEY & BALL ARCHITECTS.


text:
Garuda Indonesia's first ATR 72-600 enters commercial service
Garuda Indonesia has officially celebrated the first day of commercial service of its first ATR 72-600, with the aircraft taking to the sky from Denpasar (Bali), continuing through its inaugural day by landing at the airports of Labuan Bajo (East Nusa Tenggara province) and Bima (West Nusa Tenggara province).
The aircraft is the first of 25 firm ATR 72-600 orders, plus 10 options, put into the airline's fleet in a joint agreement between Garuda, ATR and leasing firm Nordic Aviation Capital. The airline's regular scheduled operations with these new ATRs will start on 3 December, with flights scheduled from Bali to Labuan Bajo and Ende, and from Bali to Bima and Mataram.
To optimise the operation of this new fleet of ATR 72-600s, Garuda Indonesia and ATR have recently signed a Global Maintenance Agreement (GMA) extending over 10 years and covering the 25 aircraft fleet. Based on this agreement, ATR will handle – from its Customer Support Center in Singapore – the management of the maintenance activities of Garuda Indonesia's ATR fleet, while ensuring the availability of key spare parts, such as propellers and fuel nozzles.
Commenting on the first take-off of this ATR aircraft, Emirsyah Satar, president and CEO of Garuda Indonesia, declared, "Today's flight is a major milestone in our policy of expanding regional connectivity across our country. The introduction of our new modern regional ATR turboprop aircraft represents a big step for our 'Quantum Leap 2011-2015' transformation and expansion programme, which aims to specially strengthen our domestic service".
Satar added, "This ATR 72-600 with our "Explore" brand will increase the connectivity between new tourism and new economic growth destinations in remote areas as well as to explore the richness and diversity of Indonesia."
BOC Aviation delivers new A320neo to Qingdao Airlines
IBA Group predicts Paris air show orders could be down
MAX getting a makeover…


text:
Travel bans due to new COVID-19 strain force WTO to postpone key ministerial meet
Latest on coronavirus outbreak
12th Ministerial Conference was scheduled to discuss licensing issues, vaccine property rights, supplies to fight pandemic
Peter Kenny | 27.11.2021
WTO Director-General Ngozi Okonjo-Iweala
The World Trade Organization Saturday postponed its in-person ministerial conference next week after the "outbreak of a particularly transmissible strain of the COVID-19 virus" forced several countries to impose travel restrictions.
"The WTO's General Council agreed to postpone the imminent Ministerial Conference after an outbreak of a particularly transmissible strain of the COVID-19 virus led several governments to impose travel restrictions that would have prevented many ministers from reaching Geneva," the WTO said after an emergency meeting.
The meeting was scheduled to discuss issues such as licensing and intellectual property rights around vaccines and other critical supplies used to fight the pandemic that has wreaked havoc over almost two years on international business and trade.
Around 4,000 ministers and other trade officials were expected to travel to Geneva for the WTO's 12th Ministerial Conference that was due to run from Nov. 30 to Dec. 3.
However, the announcement of travel restrictions and quarantine requirements in Switzerland and other European countries led it to call an emergency meeting of all the WTO members to inform them of the situation.
"This has not been an easy recommendation to make," said WTO Director-General Ngozi Okonjo-Iweala after the body governing international commerce postponed its planned ministerial meeting for the second time in two years.
Err on side of caution
"But as Director-General, my priority is the health and safety of all MC12 participants – ministers, delegates, and civil society. It is better to err on the side of caution," she said.
The pandemic forced a second postponement of the 12th Ministerial Conference as it was initially scheduled in June 2020 in Nur-Sultan, Kazakhstan.
On Friday, the World Health Organization declared the new COVID-19 variant announced in South Africa with many mutations a "variant of concern," naming it Omicron.
Switzerland announced it would ban all direct flights from southern Africa after the WHO said that Omicron is a potentially riskier strain.
Other European countries and the United States halted air travel from southern Africa due to concerns about the Omicron variant.
EU members agreed to impose restrictions on seven African countries – Botswana, Eswatini, Lesotho, Mozambique, Namibia, South Africa, and Zimbabwe.
Okonjo-Iweala noted that postponement of the meeting would keep the WTO in line with Swiss health regulations, and the organization did not name a new date for the meeting.
The WTO pointed out that many delegations had long maintained that meeting virtually does not offer the interaction necessary for holding complex negotiations on politically sensitive issues.
The Geneva-based WTO's 164 members set rules for international commerce, and it is supposed to resolve trade disputes between its members legally.
COVID-19 omicron variant travel bans WTO
Hong Kong shuts secondary schools due to virus outbreaks
Daily virus cases hit 6-month peak in Uzbekistan


This week Apparent Failure to Vote Notices will be sent to electors in the Darling Range electoral district who appear not to have voted in the recent by-election. If they don't have a valid and sufficient reason for not voting they will be fined $20 for a first offence or $50 if they've been penalised for not voting before.
If this might be you, or someone you know, visit Failure-vote for more information. Payment of fines is due by 26 October 2018.
With regards the Cottesloe by-election, non-voters who haven't responded to the three notices they've been sent, now face having the matter referred to the Fines Enforcement Registry and the possibility of their driver's licence being suspended.


text:
Васи́ль Наза́рович Ру́дик (, с. Жубровичі, Олевський район, Житомирська область, УРСР) — український політик, народний депутат України І скликання, кандидат економічних наук, також працював заступником керівника Управління забезпечення міжпарламентських зв'язків — завідувачем відділу забезпечення зв'язків з національними парламентами Апарату Верховної Ради України.

Життєпис

Василь Назарович Рудик народився 9 травня 1941 року в селі Жубровичі, Олевський район, Житомирська область). Українець.

Освіта:Українська сільськогосподарська академія, вчений-агроном; Вища партійна школа при ЦК КПУ; кандидатська дисертація «Підприємництво: економічна сутність, механізм функціонування та розвитку» (Київський університет імені Тараса Шевченка, 1993).

Народний депутат України 12(1) скликання з 03.1990 (2-й тур) до 04.1994, Олевський виборчій округ № 165, Житомирська область. Голова підкомісії з питань переселення Комісії з питань Чорнобильської катастрофи.

 1958 — водій, колгосп імені Шевченка Олевського району.
 З 1958 — водій Олевського кар'єроупрвління Житомирської області.
 З 1960 — служба в армії.
 З 1963 — технік, начальник відділення, механік БАМ 164 в/ч 36846, Олевський район.
 З 1967 — технік, науковий працівник обласної дослідної сільськогосподарської станції, село Грозине Коростенського району Житомирської області.
 З 1971 — головний агроном, голова колгоспу, директор радгоспу імені Шевченка Олевського району.
 З 1979 — начальник Олевського районного сільськогосподарського управління.
 1980-04.1991 — другий, перший секретар Олевського райкому КПУ.
 1991-04.1992 — голова Олевської райради та райвиконкому.
 З 04.1992 — голова Олевської райради народних депутатів.
 З 1994 — перший секретар, з 1996 — радник Посольства України в Російській Федерації.

Нагороди
 Орден Трудового Червоного Прапора.

Примітки

Джерела

Політики України
Кавалери ордена Трудового Червоного Прапора
Народні депутати України 1-го скликання
Кандидати економічних наук України
Випускники Вищої партійної школи при ЦК КПУ
Випускники Української сільськогосподарської академії
Народились 1941
Народились 9 травня
Уродженці Олевського району


Job ID: 811481 | Amazon.com Services, Inc.
Amazon Business (AB) is a marketplace on Amazon.com that combines the selection, convenience and value customers have come to know and love from Amazon, with new business features and unique benefits that address the needs of businesses. As we scale, we need to build experiences for business customers to move their planned spend on a recurring basis to Amazon Business. Enterprise customers want to leverage AB to access millions of products, business-only selection, free two-day shipping, business pricing, multi-user business accounts, approval workflow, business payment solutions, tax exemptions, dedicated business customer support and much more. Business customers require a seamless experience that cuts across planning, negotiating, order placement, responsive adjustments to schedules and reconciliation.
The next step in scaling Amazon Business is driving growth through customer acquisition. Our customer Registration and Verification solutions are critical to bring more accounts to Amazon Business in a way that will delight our new customers.
You will build new services and experiences and be working with new technologies that improve usability and increase performance and scalability. You will also work with a wide range of teams across Amazon.
We prefer engineers who can thrive in a fast paced, high energy and fun work environment where we deliver value incrementally and frequently. We value highly technical people who know their subject matter deeply and are willing to learn new areas. We look for individuals who know how to deliver results and show a desire to develop themselves, their colleagues, and their career.
This is a rare opportunity to make a real impact at Amazon.
· Proficiency in developing software in at least one modern programming language such as Java, C#, C++, or Scala. Experience with Java Spring is a plus.


Yahoo started itself from America but now it is popular worldwide. The free email services offered by Yahoo is appreciated by millions of users on an international scale. Nowadays Yahoo is not limited to emails services but offers other services namely: Yahoo Mail, Yahoo news, Yahoo Sports, Yahoo Finance, Yahoo celebrity, Yahoo style, Yahoo weather, flicker and more. After America, the second major region where Yahoo is used the most is Canada. Therefore, the brand offers special support to its Canadian users, so that they can enjoy their Yahoo product without any hindrance.
Yahoo understands the need for direct support services for users and hence it provides country-specific support to its users. The support provided to the users is for making their experience pleasant and free from ever hurdle. Here are the numerous ways to reach the Yahoo technical support which are listed below. The Canada residents are privileged to have their special support service team. Also, the same number can be used by America-based Yahoo users and vice versa.
Either you can make a call on support number, send mail letters of the office address or browse the official website meant for Canadian Yahoo users.
Here you can access different services offered by Yahoo, create a new account, and access all other products and services offered by Yahoo.
156 Front St W, Toronto, ON M5J 2L6, Canada.
This page lets you connect with the Yahoo officials, check the updates in Tweets and send a message to the Yahoo support team.
5250 NE Elam Young Pkwy suite 900 Hillsboro, OR, United States.


Go.NIU is a URL shortening service for Northern Illinois University. Use this service when you would like a shorter URL while retaining the niu.edu domain.
Authentication with an NIU Account ID is required to create short URLs. This service is available only to NIU faculty, staff and students. Redirection via short URLs is available to all users and does not require a login.


Margiela, the "invisible" designer, who was fashion's founding father of recycling and deconstruction, is the exhibition's hero, with a section devoted – behind a "all" of silver ribbons – to his recycled clothes, including a jacket with three arms and shoes shaped with toes. Margiela was perhaps the first designer to be an activist against fashion waste – the antithesis of today's fast fashion. Missing was a series of videos or digitalised pictures that could have emphasised that role.
Yet this exhibition seems more like a wistful memory of things past than Belgian designers in today's dynamic.
The most effective area displays small "cabins", where designers have been invited to express their visual personalities: a striking A.F. Vandevorst space has a bed with the designers' signature red cross; Jean-Paul Lespagnard expresses his look via scarves and funky bottles; Raf Simons shows a single portrait; and Dries Van Noten has a wall with pictures inset with films of his shows.


text:
[Curiosities about the Life of Albert Szent-Györgyi]
VÉRTES László
[Melatonin, sleep and the circadian rhythm: theoretical considerations and their chronopharmacological applications ]
BÓDIZS Róbert
[The predictive homeostasis of living organisms is an anticipatory adaptation to rhythmical environmental changes. A good example for this is the circadian rhythm preparing the organism for the alternation of day and night. The circadian rhythm of melatonin production anticipates the timing and duration of nocturnal sleep of human subjects. It also induces a sleep-like stimulusprocessing mode of the brain and - in case of adequate environmental circumstances - a soporific and in part, a sleep-inducing effect. Specificities of melatonin effects on sleep are the reduction of slow-wave EEG activity, as well as the increase in seep EEG spindling and REM sleep time. Like other substances with hypnotic properties, melatonin decreases core body temperature, but has also a strong chronobiotic effect that is expressed as rapid and strong phase shifts of the circadian rhythm, depending on the time of day of melatonin administration. Because light acutely suppresses melatonin production, adequately timed light exposition, containing also low wavelength components, together with exogenous melatonin, could be useful in treating jet-lag syndrome and other circadian rhythm disorders.]
[Original and generic drugs: Research, efficacy, utilization, and financing ]
NOSZÁL Béla
[Starting from the definition of medicinal drugs, this paper covers the terms of original, active principles, original and generic drugs, and their distinctive and identical properties. It also surveys the fundamentals of drug-marketing authorization, criteria of therapeutic and bioequivalence, pharmaceutical and pharmacokinetic equivalence, and development possibilities of generic drugs.]
[Use of proton pump inhibitors in practice]
DEMETER Pál
[Off-label drug prescription in crossfire]
BÖLCS Ágnes
[What to do with tinnitus? - Differential diagnostical and therapeutical guideline]
GERLINGER Imre
Life threatening rare lymphomas presenting as longitudinally extensive transverse myelitis: a diagnostic challenge
TOLVAJ Balázs, HAHN Katalin, NAGY Zsuzsanna, VADVÁRI Árpád, CSOMOR Judit, GELPI Ellen, ILLÉS Zsolt, GARZULY Ferenc
Background and aims – Description of two cases of rare intravascular large B-cell lymphoma and secondary T-cell lymphoma diagnosed postmortem, that manifested clinically as longitudinally extensive transverse myelitis (LETM). We discuss causes of diagnostic difficulties, deceptive radiological and histological investigations, and outline diagnostic procedures based on our and previously reported cases. Case reports – Our first case, a 48-year-old female was admitted to the neurological department due to paraparesis. MRI suggested LETM, but the treatments were ineffective. She died after four weeks because of pneumonia and untreatable polyserositis. Pathological examination revealed intravascular large B-cell lymphoma (IVL). Our second case, a 61-year-old man presented with headache and paraparesis. MRI showed small bitemporal lesions and lesions suggesting LETM. Diagnostic investigations were unsuccessful, including tests for possible lymphoma (CSF flow cytometry and muscle biopsy for suspected IVL). Chest CT showed focal inflammation in a small area of the lung, and adrenal adenoma. Brain biopsy sample from the affected temporal area suggested T-cell mediated lymphocytic (paraneoplastic or viral) meningoencephalitis and excluded diffuse large B-cell lymphoma. The symptoms worsened, and the patient died in the sixth week of disease. The pathological examination of the presumed adenoma in the adrenal gland, the pancreatic tail and the lung lesions revealed peripheral T-cell lymphoma, as did the brain and spinal cord lesions. Even at histological examination, the T-cell lymphoma had the misleading appearance of inflammatory condition as did the MRI. Conclusion – Lymphoma can manifest as LETM. In cases of etiologically unclear atypical LETM in patients older than 40 years, a random skin biopsy (with subcutaneous adipose tissue) from the thigh and from the abdomen is strongly recommended as soon as possible. This may detect IVL and provide the possibility of prompt chemotherapy. In case of suspicion of lymphoma, parallel examination of the CSF by flow cytometry is also recommended. If skin biopsy is negative but lymphoma suspicion remains high, biopsy from other sites (bone marrow, lymph nodes or adrenal gland lesion) or from a simultaneously existing cerebral lesion is suggested, to exclude or prove diffuse large B-cell lymphoma, IVL, or a rare T-cell lymphoma.
Simultaneous subdural, subarachnoideal and intracerebral haemorrhage after rupture of a peripheral middle cerebral artery aneurysm
BÉRES-MOLNÁR Anna Katalin, FOLYOVICH András, SZLOBODA Péter, SZENDREY-KISS Zsolt, BERECZKI Dániel, BAKOS Mária, VÁRALLYAY György, SZABÓ Huba, NYÁRI István
The cause of intracerebral, subarachnoid and subdural haemorrhage is different, and the simultaneous appearance in the same case is extremely rare. We describe the case of a patient with a ruptured aneurysm on the distal segment of the middle cerebral artery, with a concomitant subdural and intracerebral haemorrhage, and a subsequent secondary brainstem (Duret) haemorrhage. The 59-year-old woman had hypertension and diabetes in her medical history. She experienced anomic aphasia and left-sided headache starting one day before admission. She had no trauma. A few minutes after admission she suddenly became comatose, her breathing became superficial. Non-contrast CT revealed left sided fronto-parietal subdural and subarachnoid and intracerebral haemorrhage, and bleeding was also observed in the right pontine region. The patient had leucocytosis and hyperglycemia but normal hemostasis. After the subdural haemorrhage had been evacuated, the patient was transferred to intensive care unit. Sepsis developed. Echocardiography did not detect endocarditis. Neurological status, vigilance gradually improved. The rehabilitation process was interrupted by epileptic status. Control CT and CT angiography proved an aneurysm in the peripheral part of the left middle cerebral artery, which was later clipped. Histological examination excluded mycotic etiology of the aneurysm and "normal aneurysm wall" was described. The brain stem haemorrhage – Duret bleeding – was presumably caused by a sudden increase in intracranial pressure due to the supratentorial space occupying process and consequential trans-tentorial herniation. This case is a rarity, as the patient not only survived, but lives an active life with some residual symptoms.
[Health status and costs of ambulatory patients with multiple sclerosis in Hungary]
PÉNTEK Márta, GULÁCSI László, RÓZSA Csilla, SIMÓ Magdolna, ILJICSOV Anna, KOMOLY Sámuel, BRODSZKY Valentin
[Background and purpose - Data on disease burden of multiple sclerosis from Eastern-Central Europe are very limited. Our aim was to explore the quality of life, resource utilisation and costs of ambulating patients with multiple sclerosis in Hungary. Methods - Cross-sectional questionnaire survey was performed in two outpatient neurology centres in 2009. Clinical history, health care utilisation in the past 12 months were surveyed, the Expanded Disability Status Scale and the EQ-5D questionnaires were applied. Cost calculation was conducted from the societal perspective. Results - Sixty-eight patients (female 70.6%) aged 38.0 (SD 9.1) with disease duration of 7.8 (SD 6.7) years were involved. Fifty-five (80.9%) had relapsing-remitting form and 52 (76.5%) were taking immunomodulatory drug. The average scores were: Expanded Disability Status Scale 1.9 (SD 1.7), EQ-5D 0.67 (SD 0.28). Mean total cost amounted to 10 902 Euros/patient/year (direct medical 67%, direct nonmedical 13%, indirect costs 20%). Drugs, disability pension and informal care were the highest cost items. Costs of mild (Expanded Disability Status Scale 0-3.5) and moderate (Expanded Disability Status Scale 4.0-6.5) disease were 9 218 and 17 634 Euros/patient/year respectively (p<0.01), that is lower than results from Western European countries. Conclusion - Our study provides current inputs for policy making and contributes to understanding variation of costof- illness of multiple sclerosis in Europe.]


text:
Andrea La Torre (Viterbo, ) é um basquetebolista profissional italiano que atualmente joga na Lega Basket e Euroliga pelo EA7 Olimpia Milão. O atleta possui 2,04m e atua na posição Ala.

Naturais de Viterbo
Basquetebolistas do Olimpia Milão
Basquetebolistas da Itália
Basquetebolistas do Pallacanestro Biella


text:
'The Office' star set for Ro-Na on Saturday
Published 1:37 am Thursday, June 2, 2022
By Heath Harrison
Comedian David Koechner, whose credits include Saturday Night Live and The Office, will be appearing at the Ro-Na Theater on Saturday night. (Submitted photo | Mandee Johnson)
"They're definitely up there with Star Wars and Star Trek," comedian David Koechner said of the level of devotion fans of The Office still maintain for the show nearly a decade after its conclusion.
Koechner, who had a recurring role on the show as Todd Packer, is set to make two appearances in the region for fans, appearing at this weekend's Huntington Comic and Toy Convention, as well as hosting a trivia event for the sitcom at the Ro-Na Theater in Ironton at 7:30 p.m. on Saturday.
Beginning in improv, Koechner has amassed a large resume of more than 600 projects in film and television, spanning comedy, drama and animation.
In addition to The Office, he's best known for his supporting role as sportscaster Champ Kind in Judd Apatow's two "Anchorman" films, which starred his fellow Saturday Night Live cast member Will Ferrell.
Koechner appeared on Saturday Night Live from 1995-1996 and his year on the show contained characters which have had enduring popularity, such as one of the drunken businessmen who would regale others of their seemingly superhuman co-worker Bill Brasky's feats, and as Fagan, one of two preening British men in powdered wigs and period clothing (along with Mark McKinney) who would appear on Weekend Update as obsessive fans of anchor Norm MacDonald.
The show also featured one of his characters which has been a staple of his live shows, as well as a Comedy Central series, Gerald "T-Bones" Tibbons, an off-color southern oddball who Koechner said was based on a man encountered growing up in Missouri named "Four-way George."
"He would hang out on the chopped off telephone post at the intersection," Koechner said of the drifter who worked as a roofer. "He had bushy hair and was a bit sullen. He would play pull and tell adventure stories. He never did anything wrong, but they always wanted to run him out of town."
Many of Koechner's characters have garnered a cult following, but he said his part on The Office is easily the one that brings out the most fans, but adds that he meets fans from all of his work, from his comedy work to cult films like "Cheap Thrills" and "Krampus."
Koechner's recurring role as Packer, the crude, alcoholic traveling salesman with basically no redeeming values, was a reinterpretation of a part from the British version of the sitcom.
Koechner said he enjoyed playing such a type.
"Because I never act anything like that," he said. "You can't act like that and get away with it."
Koechner said he likens Packer's persona to a "guy who goes to someone's house and they draw him a nice warm bath, then he splashes all the water out of the tub onto the floor and, when he get out, he steals the best robe."
Koechner said he has been doing the touring trivia show since March, in which he appears in character for part of the event, as well as tells backstage stories of the making of the show.
While he said there is no prize for the trivia game, other than "the joy of doing it," it gives fans to a chance to meet up, "match wits" and share their love of the show.
Koechner said he has been amazed at the level of knowledge fans have of the show.
"It's really incredible," he said. "It is unmatched what they know – more than any other project I've worked on."
As for upcoming work, Koechner said he is currently working on a new sitcom, as well as a game show, which are in the early stages and has several films lined up.
Tickets for the 90-minute event at the Ro-Na are $25 and can be purchased at https://www.eventbrite.com/e/the-office-trivia-with-the-real-todd-packer-tickets-339237858567. The theater is located at 310 S. Third St. in Ironton.
Koechner will be appearing both Saturday and Sunday at the Huntington Comic and Toy Convention, which will take place at Mountain Health Arena. Tickets are available for that event at www.huntingtoncomiccon.com.