What is Schools to Watch? Schools to Watch is a partnership between the South Carolina association for Middle Level Education and the SC Middle Grades Initiate. As an affiliate of the National Forum to Accelerate Middle-Grades Reform's National Schools to Watch program, SC seeks to help schools on a trajectory toward excellence through providing strong criteria for being a high performing school.
What is the National Forum to Accelerate Middle-Grades Reform?
The "National Forum" is an alliance of over 60 educators, national associations, and officers of professional associations and foundations committed to promoting the academic performance and healthy development of young adolescents. The National Forum, which developed the original Schools to Watch criteria, serves Pennsylvania as a source of inspiration and expertise. The National Forum convenes the annual national Schools to Watch conference (June, Washington D.C.). This conference is open to both Schools to Watch and those that aspire to become Schools to Watch. In addition, the National Forum is a recipient of a 2010 Federal i3 grant of $6,000,000.00 for middle grades school improvement.
What does it mean to be a School to Watch School? Schools to Watch seeks to recognize a diverse, high-performing, growth-oriented middle grades schools to demonstrate what all middle grades schools are capable of achieving.
Academic Excellence. High-performing schools with middle grades are academically excellent. They challenge all students to use their minds well.
Developmental Responsiveness. High-performing schools with middle grades are sensitive to the unique developmental challenges of early adolescence.
Social Equity. High-performance schools with middle grades are socially equitable, democratic and fair. They provide every student with high-quality teachers, resources, learning opportunities, and supports. They keep positive options open for all students.
Organizational Structures and Processes. High-performing schools with middle grades are learning organizations that establish norms, structures, and organizational arrangements to support and sustain their trajectory toward excellence.
A School to Watch School is a school that is conscientiously moving to meet fully the nationally endorsed criteria for high-performing middle schools, one that has made marked progress in meeting all of the criteria, including measurable gains in the academic achievement of all students over time.
How is Schools to Watch different than other recognition programs? Designations are earned based on achievement across the domains of academic excellence, developmental responsiveness, social equity and school organization. Schools are recognized and celebrated for their growth and development.
When are Applications due?Applications are usually due in September.
Why should our school apply to be a School to Watch?The foundation of the Schools to Watch Program (and application process) is the self-study tool containing the National Forum Schools to Watch criteria. The National Forum believe that youth in the middle grades are capable of learning and achieving at high levels. We share a sense of urgency that high-performing middle grades schools become the norm, not the exception. To that end, the National Forum identified a set of selection criteria to describe high-performing schools that serve students in the middle grades. South Carolina adopted these criteria in the form of the self-rating rubric. To begin the application process, a school must convene a school learning community to investigate their achievement in the areas of academic excellence, developmental responsiveness, social equity and school organization. The insights revealed through the use of this rubric are powerful and rewarding.
What if we begin the application process and realize we are not ready to be a School to Watch? Should we submit our application?
Yes! From the moment you begin working with the self-rating rubric, you are increasing your school's capacity for self-improvement. Even if you are not ready to be designated a School to Watch you can receive valuable feedback on your school's application and join the Schools to Watch Network. In the event your application is of great interest to the readers, you may receive a site visit from middle grades experts that will provide you with additional feedback. Even schools that receive the designation begin a process of continual school improvement with the support of the South Carolina Schools to Watch team.
What process is used to determine if a school is designated a School to Watch school??The National Forum to Accelerate Middle-Grades Reform crafted a vision that describes the characteristics of high-performing middle grades schools. With this vision as a basis, National Forum members then developed a set of rigorous criteria that could be used to identify such high-performing schools. These became known as the Schools to Watch criteria.
The STW criteria themselves are important, since they represent a set of rigorous, research-based indicators against which schools can measure their own performance and set improvement benchmarks. In addition, they serve as the basis for identifying exemplars at the state level.
Using a rubric fashioned upon the national STW criteria, Schools to Watch State Team members evaluate applications for "potential" schools to serve as designees. It is important to note that schools do not compete with each other for designations, but rather they compete with the rigorous criteria used to identify high-performing schools. If your application is of great interest to the readers, you will be selected for site visitation. A group from the larger Schools to Watch State Team will spend at least one day in your school further evaluating your application and your potential to serve as a high-performing, growth-oriented middle grades school that will demonstrate what all middle grades schools are capable of achieving.
State Team members currently include diverse, talented, experienced professionals working in the area of middle school improvement. Members work in various capacities, i.e. middle school teachers and counselors, middle school administrators, district administrators, college and university professors and administrators, etc.
What if we apply and are not designated as a School to Watch?
Receiving feedback and support from the Schools to Watch Team.
IF NOT SELECTED, SCHOOLS TO WATCH STRONGLY ENCOURAGES YOU TO REAPPLY THE FOLLOWING YEAR. Nation-wide, it is not unusual for a School to Watch to have applied to the program more than once before receiving the designation. Several schools have applied more than one time before being recognized. Currently, there are more than 450 Schools to Watch in the nation. Schools to Watch is both a recognition and capacity building program. Our hope is that you continue to find the self-study/application process and overall programming instructional and inspiring.
If we are designated as a School to Watch, what is our role in middle grades reform? What are our responsibilities?If you are designated as a School to Watch, you agree to participate in all aspects of the program including, but not limited to, recognition celebrations, induction and orientation, professional development and school improvement consultations, visits from others who seek to improve their schools, STW Network/SCAMLE member, and documentation of Schools to Watch practices. A designee recognizes that being a School to Watch demands increased attention to high, dynamic and sustained performance. A designee welcomes the opportunity to share knowledge and experience with others and works as a mentor to accelerate middle grades reform in South Carolina.
What benefits are associated with being designated a School to Watch?While being selected as a School to Watch provides others with a representative model of how effective middle grades schools work, it also provides the receiving school an opportunity for new reflection, professional development and consultation, and Schools to Watch community involvement via the state and national network of Schools to Watch. As there are currently more than 450 Schools to Watch in the nation, a South Carolina School to Watch is recognized as a forward thinking, achievement and equity-driven organization committed to the development of both young adolescents and adult learners.
Can a School to Watch reaffirm their designation in consecutive years?A school receives a designation for three consecutive years. To reaffirm status, the school must annually review its programs and keep the state School to Watch Leadership Team apprised of their continuous improvement. The redesignation process is completed every three years. It includes an extensive application, site visit, and interviews.
Please direct all questions to a member of the Schools to Watch State Leadership Team.


LEBANON, Tenn. – Five Cumberland track and field athletes – Sydney Clere, Dylon Dishman, Parker Kuchek, Bumnene Ndebele and Charles Shimukowa – were named Academic All-Mid-South Conference, as announced Wednesday by the league office in advance of this week's conference championships in Williamsburg, Ky.
LEBANON, Tenn. – Cumberland men's basketball coach Jeremy Lewis announced the signing of Carbon Hill, Ala., native Isaac Woodard to scholarship papers this week for the 2019-20 academic year.
LEBANON, Tenn. – Cumberland women's basketball coach Scott Blum announced the signing of Old Hickory, Tenn., native Autumn Groves to scholarship papers this week for the 2019-20 academic year.
LEBANON, Tenn. – Hector Torres belted two homers and drove in seven runs while Malique Foreman added four hits and Sawyer Stevens tossed five shutout innings for the win in Reinhardt University's 11-1 victory over Cumberland in baseball action here Wednesday at Ernest L. Stockton Field-Woody Hunt Stadium.
LEBANON, Tenn. – Cumberland women's tennis moved up one spot to No. 20 in the latest NAIA Coaches' Top 25 Poll released Tuesday by the national office.
LEBANON, Tenn. – Cumberland men's tennis remained 16th in the latest NAIA Coaches' Top 25 Poll released Tuesday by the national office.


text:
At Work With . . . Paula Wrightson
by admin | posted in: At Work With . . ., Behind the Scenes, Ghosts, Paula Wrightson, Preston Manor, Stanford Family, Weird and Wonderful | 2
…Paula Wrightson, Museum Learning Officer (Adult event programme)
I have been working with the ghosts at Preston Manor for five years although I've yet to actually meet one.
In this time I've become fascinated not only by our famous Preston Manor ghost story but by the history of belief in ghosts, especially in the Victorian period. The Victorians went ghost crazy and the Stanford family of Preston Manor appear to have been drawn into the fad.
I have been lucky enough to read the letters written in the 1930s between John Benett-Stanford and Henry Roberts, the first curator of the Manor when it became a museum in 1933. It is through these letters that we can piece together some of the story. What is known is that Lady Ellen Stanford certainly did not believe her house was haunted "personally I do not believe anyone has ever seen one here" she wrote of ghosts in 1930.
[slideshow]
However, her mother was so convinced she took part in a séance, which was held at the house on 11th November 1896. At this time holding a séance was fashionable in high society. Even Queen Victoria is said to have dabbled. Spiritualist mediums could make a good living on the grand house circuit and many, interestingly, were women, as the job was considered a respectable profession (especially for genteel ladies in need of an income).
The medium present at the Preston Manor séance was Ada Goodrich Freer, going under the pseudonym 'Miss X'. She became a leading member of the Society for Psychical Research which was set up in 1882 and continues today. Without doubt Miss X provided a dazzling show that November night. A transcript of the proceedings still exists from which we can deduce a 'talking board' was used (marketed as the Ouija Board from 1901). Miss X's fantastical communications with 'the other side' (too lengthy to go into here) together with the archive of letters, provide us with the basis of the ghost tours and events that we run at Preston Manor today.
John Benett-Stanford, who was not present at the séance, intended writing a history of his family ghost story but in his own words he was "too lazy" to do so. He hoped Henry Roberts would take up the mantle and wrote numerous lines of enquiry to Roberts including the hope that the household ghost of the White Lady might call by one night and "share your whisky and soda with you".
No one has yet written the definitive history of the Preston Manor ghosts, not least because the story continues. I keep an on-going file of up-to-date reports of sightings and experiences.
Share on FacebookShare on TwitterShare on LinkedinShare on Pinterest
Ada Goodrich Freer, April 2011, Ellen Stanford, Ghost, Henry Roberts, John Benett-Stanford, Miss X, Ouija Board, Preston Manor, Queen Victoria, Séance, Society for Psychical Research
alison wadey
May 5, 2011 | Reply
love this story and i really wished you guys would let our group do an investigation at your museum , we have insurance and our own security team if required check our website out you can see we are legitimate and serious about the work we do, who knows we may even be able to fill in the gap in the history if i get a good link with any / if any spirits there 🙂
thanks for the story love history of our home town
Royal Pavilion & Brighton Museums
Thanks for your comment Alison. Preston Manor is available for hire by paranormal investigative groups. You can call our bookings team on 03000 290902 for details. You can also find more informaton on our ghost tours here: http://ow.ly/4NJ1Q.

redpajama_set_name: RedPajamaCommonCrawl


text:
Timing of puberty controlled by genes
By Dr Rosie Morley
Researchers have identified genetic factors that are involved in determining the age at which a child reaches puberty, in a genome-wide study looking at over 182,000 women.
A large collaboration of researchers across 166 research centres studied the genomes of 182,416 women and the age at which they reached their first period. The scientists discovered associations with multiple genomic regions, indicating that genetic factors play an important role in the age of puberty, in addition to known environmental factors.
'There is a remarkably wide diversity in puberty timing - some girls start at age eight and others at 13', said Dr Ken Ong from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge and senior author of the study. 'While lifestyle factors such as nutrition and physical activity do play a role, our findings reveal a wide and complex network of genetic factors', he said.
Understanding the timing of puberty is important because it can influence the risk of developing certain disorders later in life. Dr Ong said, 'We are studying these factors to understand how early puberty in girls is linked to higher risks of developing diabetes, heart disease and breast cancer in later life – and to hopefully one day break this link'.
Many of the regions of DNA that were identified in this study were found to be located in imprinted regions of the genome. Usually, both copies of a gene (one from the mother and one from the father) are equally active; however, in imprinted regions of DNA, genes from only one parent are expressed, while genes from the other are silenced.
Lead author of the study, Dr John Perry from the MRC Epidemiology Unit at the University of Cambridge, said: 'Our findings imply that in a family, one parent may more profoundly affect puberty timing in their daughters than the other parent'.
This is the first study to show an effect of imprinted genes on development after birth. Dr Perry said, 'We knew that some imprinted genes control antenatal growth and development – but there is increasing interest in the possibility that imprinted genes may also control childhood maturation and later life outcomes, including disease risks'.
Many of the genes identified have known links to puberty, and the study also identified genes involved in regulating body weight, and implicated in rare pubertal disorders as being important for the timing of puberty.
A co-author of the study Dr Anna Murray, from the University of Exeter Medical School, commented, 'We found that there are hundreds of genes involved in puberty timing, including 29 involved in the production and functioning of hormones, which has increased our knowledge of the biological processes that are involved, in both girls and boys'.
Age of puberty in girls influenced by which parent their genes are inherited from
University of Cambridge (press release) | 23 July 2014
Genetic clues to age of first period
BBC News | 24 July 2014
One Parent May Have Bigger Role in a Girl's Puberty Age
Yahoo! News | 25 July 2014
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
Nature | 23 July 2014
The Genetics of Menarche
The Scientist | 24 July 2014
Early puberty linked to paternal gene mutation
10 June 2013 - by Dr Amina Aitsi-Selmi
A type of premature puberty known as central precocious puberty is caused by mutations in a gene inherited from fathers, according to a study from Brigham and Women's Hospital, USA...
Study finds genetic link between obesity and early puberty
29 November 2010 - by Chris Chatterton
An international study has uncovered new genes linked to the early onset of puberty and increased likelihood of obesity. The researchers performed a meta-analysis of 32 genome-wide association studies (GWAS) involving over 100,000 women from Europe, the US and Australia....
Gene variants influence onset of menstruation
1 May 2009 - by Heidi Colleran
The first evidence for a genetic influence on the timing of female sexual maturation has been found by an international team of scientists, led by the Institute of Biomedical and Clinical Science in the Peninsula Medical School at Exeter (PMSE). The study, reported in the journal Nature...
Puberty hormone may help infertile women
13 March 2007 - by Heidi Nicholl
Scientists at Imperial College, London have trialled a potential new treatment for infertility in healthy female volunteers. Kisspeptin is a reproductive hormone discovered in the town of Hershey, Pennsylvania and named after the town's most famous export ('Hershey's Kisses' chocolates). Mutations in the receptor for Kisspeptin result...


The nigrostriatal pathway is shown here in solid blue, connecting the substantia nigra with the dorsal striatum.
The nigrostriatal pathway or the nigrostriatal bundle (NSB), is a dopaminergic pathway that connects the substantia nigra with the dorsal striatum (i.e., the caudate nucleus and putamen). It is one of the four major dopamine pathways in the brain, and is particularly involved in the production of movement, as part of a system called the basal ganglia motor loop. Dopaminergic neurons of this pathway synapse onto GABAergic neurons.
Loss of dopamine neurons in the substantia nigra is one of the main pathological features of Parkinson's disease, leading to a marked reduction in dopamine function in this pathway. Depletion of neurons in this pathway lead to the symptomatic motor deficits of Parkinson's disease including tremors, rigidity, and postural imbalance.
The following are considered part of the nigrostriatal pathway.
The substantia nigra is located in the midbrain. It has two distinct parts, the pars compacta and the pars reticulata. The pars compacta is part of the nigrostriatal pathway and relays information to the basal ganglia by supplying dopamine to the striatum. The pars reticulata in conjunction with the Globus pallidus in the basal ganglia allows for inhibition of the thalamus.
The dorsal striatum is located in the subcortical region of the forebrain. It is divided by a white matter tract called the internal capsule into two parts: the putamen and the caudate nucleus. The putamen and caudate both input information from the cerebral cortex, thalamus, and substantia nigra.
The nigrostriatal pathway connects the substantia nigra with the dorsal striatum. It is one of the four major dopamine pathways in the brain, and is particularly involved in modulation of the extrapyramidal system. Dopaminergic neurons in the nigrostriatal pathway synapse onto GABAergic neurons in the basal ganglia. and in part make up the basal ganglia motor loop. Along with the other dopaminergic pathways, it is also partially involved in reward and in the reinforcement of memory consolidation.
The nigrostriatal pathway influences two other pathways, the direct pathway of movement and the indirect pathway of movement.
The direct pathway is involved in facilitation of wanted movements. The projections of the caudate, putamen, internal segment of the globus pallidus, and the substantia nigra pars compacta create an excitatory effect on the thalamus by decreasing the GABA released by the striatum. This inhibitory effect decreases inhibitory projections from the thalamus, creating an overall net excitatory effect.
The indirect pathway is involved in preventing unwanted movement. The projections of the caudate, putamen, external segment of the globus pallidus, and substantia nigra pars reticula create an inhibitory effect on the thalamus through the release of GABA. This inhibitory effect decreases the excitatory projections from the thalamus, creating an overall net inhibitory effect on movement.
Parkinson's disease is characterized by severe motor problems, mainly hypokinsia, rigidity, tremors, and postural imbalance. Loss of dopamine neurons in the nigrostriatal pathway is one of the main pathological features of Parkinson's disease. Degeneration of dopamine producing neurons in the substantia nigra pars compacta and the putamen-caudate complex leads to diminished concentrations of dopamine in the nigrostriatal pathway, leading to reduced function and the characteristic symptoms. The symptoms of the disease typically do not show themselves until 80-90% of dopamine function has been lost.
Levodopa-induced dyskinesias (LID) is a complication associated with long-term use of the Parkinson's treatment L-DOPA characterized by involuntary movement and muscle contractions. This disorder occurs in up to 90% of patients after 9 years of treatment. The use of L-DOPA in patients can lead to interruption of nigrostriatal dopamine projections as well as changes in the post-synaptic neurons in the basal ganglia.
1 2 Tritsch, NX; Ding, JB; Sabatini, BL (Oct 2012). "Dopaminergic neurons inhibit striatal output through non-canonical release of GABA". Nature. 490 (7419): 262–6. doi:10.1038/nature11466. PMC 3944587 . PMID 23034651.
↑ Wise, RA (October 2009). "Roles for nigrostriatal--not just mesocorticolimbic--dopamine in reward and addiction.". Trends Neuroscience. 32 (10): 517–524. doi:10.1016/j.tins.2009.06.004. PMC 2755633 . PMID 19758714.
↑ Cenci, Angela M (2006). "Post- versus presynaptic plastic ity in L-DOPA-induced dyskinesia". Journal of Neurochemistry. 99 (2): 381–92. doi:10.1111/j.1471-4159.2006.04124.x. PMID 16942598.
↑ Deumens, Ronald (21 June 2002). "Modeling Parkinson's Disease in Rats: An Evaluation of 6-OHDA Lesions of the Nigrostriatal Pathway". Experimental Neurology. 175 (2): 303–17. doi:10.1006/exnr.2002.7891. PMID 12061862.
↑ Groger, Adraine (8 January 2014). "Dopamine Reduction in the Substantia Nigra of Parkinson's Disease Patients Confirmed by In Vivo Magnetic Resonance Spectroscopic Imaging". PLoS ONE. 9: e84081. doi:10.1371/journal.pone.0084081.
↑ Niethammer, Martin (May 2012). "Functional Neuroimaging in Parkinson's Disease". Cold Spring Harbors Perspect in Medicin. 2 (5): a009274. doi:10.1101/cshperspect.a009274. PMC 3331691 . PMID 22553499.


text:
Johannes Junge (* wohl in Schweidnitz, wirkte um 1577, weitere Lebensdaten unbekannt) war ein deutscher Rechenmeister des 16. Jahrhunderts, der in der Hansestadt Lübeck tätig war.

Leben
Johannes Junge entwickelte eine Methode zur Ermittlung von Wurzelwerten, die besonders im 17. Jahrhundert angewandt wurde, und die er 1577 als Rechenmeister in Lübeck veröffentlichte.

Werke
 Rechenbuch auff || den Ziffern vnd Linien/ darinne aller=||ley Kauffmans handlung/ nach art der Re=||gel de Tri vnd Welschen Practica/ sampt der Regel || Falsi/ dardurch die Exempla der acht Regeln Coß || auffgeloeset werden/ Neben ausziehung der wurtzeln || Arithmetischer Progression/ So wol den Regeln Al=||gebre|| vnd andern auffloesungen Cubiccossischer || vergleichungen/ so vor niemals am || Tage gewesen/ alles ordent=||lich gestelt durch || Johann Jungen Rechenmei=||ster zu Luebeck. Lübeck: Johann Balhorn d. J. 1578 (VD16 J 1077)

Literatur

Weblinks

Rechenmeister
Person (Lübecker Geschichte)
Deutscher
Geboren im 16. Jahrhundert
Gestorben im 16. oder 17. Jahrhundert
Mann

redpajama_set_name: RedPajamaWikipedia


FC Porto will host Liverpool in the quarter-finals of the Champions League on Wednesday, April 17, 2019, at Estádio do Dragão.
Liverpool beat Porto 2-0 at Anfield in the quarter-finals of the Champions League.
Nabi Keita and Roberto Fermino scored in the fifth and 26th minutes to put England in the semi-final, while Portugal's task became more difficult.
Porto suffered from a great rebound in the counter-attacks, and could not keep up with speed and accuracy, only a 0-2 defeat, hoping to return home in the second leg.
FC Porto won 1 direct matches. Liverpool won 4 matches. 3 matches ended in a draw. On average in direct matches both teams scored a 2.13 goals per Match.
FC Porto in actual season average scored 2.11 goals per match. In 22 (81.48%) matches played at home was total goals (team and opponent) Over 1.5 goals. In 16 (59.26%) matches in season 2019 played at home was total goals (team and opponent) Over 2.5 goals.
Liverpool average scored 2.22 goals per match in season 2019. In 22 (78.57%) matches played away was total goals (team and opponent) Over 1.5 goals. In 15 (53.57%) matches played away team was total goals (team and opponent) Over 2.5 goals.


No need to worry about the hot water running out or others using it all – it's literally an endless supply of thermal spring water pumping up from underground in the middle of our red-dirt country. Douglas (or Tjuwaliyn) Hot Springs Nature Park is a must-do stop-off, even if it's only for a quick dip, if you're wondering around between Darwin and Katherine in our Northern Territory. Everyone visits Kakadu and Litchfield NP's while up in the Territory, most visit the overcrowded Mataranka Springs (more hot springs), but many miss out on or don't know about Douglas Hot Springs, which lacks the big crowds of the more popular spots. Sure Douglas lacks the deep crystal clear swimming holes of Mataranka, but at least it's all natural in its setting.
There are camp grounds here, but don't expect much in the way of lush green grass to pitch a tent on. Rather it is a large flat and level (potentially dusty depending on time of year) area perfect for camper trailers and caravans. Road conditions (while varying depending on weather and time of year) are generally good via the last stretch of graded gravel road and you'd reasonably expect an easy trip even with camper trailers or caravans in tow. We managed to be the only people there during our visit; perfect for relaxing in the warm water and teaching our little fella the fine art of swimming without the shivers.
As you're heading south from Darwin, point you bull bar onto road '23' the Old Stuart Highway (or Dorat Road), the scenic route from Adelaide River which winds it's way back onto the main track – Stuart Highway – just south of Hayes Creek. Be sure to take the turn heading (roughly) South / South / West towards Douglas Daly Park onto Oolloo Road. You'll then hook a left (back East-ish) into Hot Springs Road just before you get into Douglas Daly and find the Douglas Hot Springs Camping Area on your right a few kays down the gravel track. Missing this last turn into the camp area will see you potentially travel another 17 kays into Butterfly Gorge Nature Park, but there is a locked gate on route during the wet season.
Once you're into the camping area, set up your gear or park in the day use area, then slip into something more comfortable for a dip, but beware the water can get dangerously hot in some parts of this river. Do keep an eye on kids that they don't go headlong into the near-boiling water or become stuck in the quicksand. Sounds dangerous dunnit'; well it can be and there are plenty of signs erected to warn of the dangers so do take your time to read them. Also, do keep out of the sacred sites, of which they are an important place for Wagiman women's business ceremonies. Keep in mind that on the odd occasion the whole area may be closed due to ceremonies taking place or even if water quality drops to unhealthy levels. The Park is owned by the Wagiman people who jointly manage it with the Parks and Wildlife Commission of the Northern Territory.
For those intent on a little hiking, lace your boots up and wonder along the creek line around the hot springs or perhaps along the Douglas River. You'll potentially spot plenty of bird life during the day as well as furry creatures such as bandicoots, quolls and flying foxes at night. Crocs are reputedly non-existent down here.
With the river and hot springs creating a small oasis in what is an extremely harsh environment; take the time to relax in the warm waters amongst the dry woodlands. Savor the remoteness of it all and remember if the waters too hot, shuffle downstream a little until you get just the right temperature flowing past your weary body. Don't be in a rush, there's plenty to go 'round.
About 200km south of Darwin and 130km north of Katherine, just south of Hayes Creek. Once on road '23' the Old Stuart Highway (or Dorat Road), head towards Douglas Daly Park on Oolloo Road, then into Hot Springs Road to get to the camping area.
There is a large camping area with pit toilets, barbecues, firewood, picnic tables and water. Power is not available. Camping fees can be deposited in the honesty box provided or paid to the Campground Manager.
Best time to visit is in the dry season (May - September) as heavy rains during the wet season (October - April) may cause road closures.
Best shopping is either in Darwin or Katherine, although fuel is available much closer at Adelaide River to the north and Pine Creek to the south.
Be aware that some parts of the river are very hot, observe park safety signs.
Carry and drink plenty of water and wear a shady hat, sunscreen and insect repellent.
Wear suitable clothing and footwear both in the water and out.
Avoid strenuous activity during the heat of the day.
You're in a remote area, so ensure your vehicle is well maintained and equipped.
Men are not permitted near the sacred site.
Glass is not permitted in or near the river; people's feet are at risk.
Keep to designated roads and tracks.
All cultural items and wildlife are protected.
Nets, traps and firearms are not permitted.
Light fires only in fireplaces provided.
Soaps and detergent are not permitted in the river bed.
Check that your vehicle is not transporting pests like weeds and Cane Toads.


Baltimore County Police have charged two men in connection with a Friday morning shooting in Randallstown.
Both men are charged with attempted first degree murder and related charges and are being held without bail at the Baltimore County Detention Center.
The suspects shot the victim during an interaction in the victim's apartment.
At 10:06 a.m., Baltimore County Police responded to an apartment in the 9900 block of Cervine Lane 21133 for a shooting. Upon arriving at the scene, officers found an adult male victim suffering from at least one gunshot wound.
Two persons have been taken into custody in reference to this incident. Investigators believe that this was a targeted crime.
If you or a loved one has been charged with murder or attempted murder in Maryland, contact attorney Randolph Rice (410) 694-7291 for immediate legal help.


Dynamic timeline™ is a visual tool that gives you a real-time, birds-eye view of the project. Powerful, yet extremely easy to use.
An ideal plan is a quickly adjustable one, right?
This way, Wrike's online scheduling software helps your team always stay on course and get more things done together!
Wrike is powerful, yet easy-to-use scheduling software.
It's extensive set of features will be a great asset to anyone looking for a smart and more efficient way to get all things done.
The timeline (Gantt chart) is a perfect tool for visualizing your schedules and getting a bird's-eye view of the projects. In Wrike, the Gantt chart provides you with all the details of your projects' schedules, such as milestones, date constraints and task dependencies.
Our web-based scheduling software allows you to easily update your schedules with a quick drag-and-drop and track the progress in the real-time Activity Stream. Whenever the schedule is changed by anyone on your team, others are instantly notified about this online and via e-mail.
One glance at Wrike's workload view is enough to clearly see how assignments are distributed among your team members. Detected a schedule conflict? With Wrike's scheduling software it's not a problem! Simply drag-and-drop tasks between the team members to optimize the workload.
In Wrike, you may choose to share a project's schedules with your team, partners or even clients. It's up to you whether to share a single task's schedule or the whole workspace. This selective data sharing helps you manage multiple schedules in your Wrike account and provide your team with all the important information while avoiding cluttering their workspaces.
Our online scheduling software makes the routine of tracking sent e-mails with tasks easy and efficient. Just CC e-mails to Wrike, and they will be automatically integrated with the project's schedules! For all Outlook users, Wrike has created a special productivity booster: an add-in that provides a two-way sync for your schedules in Wrike and Outlook.
With Wrike, you'll feel comfortable managing even complex schedules. This web-based scheduling software enables you to duplicate projects, add multiple subprojects, move a task between projects, place one task in several projects and overall organize your tasks the way that suits you best.
Wrike has a fantastic visual timeline element, which makes life so much easier!
When I reschedule a task on the timeline, all the team members see it in real time. With Wrike, plan changes are no longer a headache.
Wrike's neat timeline is perfect for a quick and well-arranged overview of all the projects.


Axis Capital Holdings Limited operates as a holding company. The Company, through its subsidiaries, offers insurance covers for property, workers compensation, professional liability, casualty, and marine and aviation. Axis Capital serves customers in the United States and Canada.


Duchenne muscular dystrophy (DMD) is a progressive form of muscular dystrophy. DMD causes progressive weakness and loss (atrophy) of skeletal and heart muscles. DMD may also affect learning and memory, as well as communication and certain social emotional skills.
Dr. Poysky is internationally recognized as an expert on Muscular Dystrophy, and is chair of a muscular dystrophy expert panel coordinated by the Centers for Disease Control and Prevention (the CDC).
He is a contributing author to "A Guide to Duchenne Muscular Dystrophy"
Dr. Poysky provides assessments for DMD patients with particular focus on domains that have a greater risk for problems in DMD.
The testing covers cognitive functioning, which usually includes: IQ(verbal and nonverbal reasoning), attention, short-term/working memory, executive functioning, academic skills, motor planning, verbal fluency, etc.
Emotional adjustment is also evaluated, including things like coping, anxiety/OCD, depression, behavioral regulation/ADHD, rigid thinking, temper outbursts, social adjustment, independence.
The specific tests to be administered will be decided after the clinical interview.


text:
Pulitzer Center Update
Pulitzer Center Announces 2012 Student Reporting Fellows
April 24, 2012 | General news, Education news
Jennifer McDonald
The Pulitzer Center and members of its Campus Consortium network have selected 10 students to receive international reporting fellowships. The fellowship recipients will report on a range of global issues from around the world, and be mentored by Pulitzer Center-supported journalists and staff over the course of their projects. The student reporting fellowships are awarded as a part of the Campus Consortium program, a growing network of 15 colleges and universities that have partnered with the Pulitzer Center.
Keyla Beebe, a junior studying English and communications at Guilford College, is the first student fellow to publish her project this year. Beebe had previously traveled throughout Latin America and Europe, and this reporting project brought her to Cambodia, where she examined the effectiveness of policies dealing with the causes of deforestation and the consequences for rural households. Read her reporting on the disappearing rainforests of Cambodia.
Guilford College is a part of geographic consortium in North Carolina's Piedmont Triad region of which High Point University and Wake Forest University are members.
Graduating senior Andrew Faust was selected as the student fellow from High Point University. His project will focus on the growing fast food industry in the United Arab Emirates and its impact on the health of the population. Faust served as the online editor of the Campus Chronicle, the university's student newspaper, and served as an online editorial intern at Scripps Networks Interactive in Tennessee. In the fall, he will begin graduate studies in health communication in the Department of Communication Studies at The University of Georgia.
The student fellow from Wake Forest University, junior Yasmin Bendaas, will travel to her family's home in the Aures Mountains of northeastern Algeria to investigate the meaning and history behind the facial tattoos of elder members of the Chaouia, an indigenous group. Bendaas is majoring in anthropology with a double minor in Middle East and South Asia studies, and journalism. She also studied Arabic at The Arabic Language Institute in Fez. Read more about her project.
Adam Janofsky, a junior at the University of Chicago, will report on energy policy in Thailand by studying the impact of energy sustainability laws on farmers, tuk tuk drivers and children. Janofsky is a double major in law, letters and society, and political science. He recently interned in the Office of the Mayor of Chicago, where he worked with the city's environmental programs. During his time in Thailand, Janofsky will also be interning at The Bangkok Post, the country's largest English language newspaper.
Graduating senior Melissa Turley is the student fellow from The George Washington University. A journalism and mass communications major, she will report on the important role of women in keeping peace in post-apartheid South Africa. Turley is the features editor of The GW Hatchet, the university's student newspaper, and an intern in the Office of Strategic Communications at the US Department of State.
Two Boston University students were selected as international health reporting fellows. Working through the Boston University Program on Crisis Response and Reporting, Meghan Dhaliwal, an undergraduate senior at the College of Communication, and Jason Hayes, a graduate student at the School of Public Health, will spend several weeks at the Pulitzer Center's Washington, D.C. headquarters and several weeks reporting, most likely from Africa on such issues as water and sanitation, and reproductive health. Dhaliwal is a photojournalism student who has traveled extensively throughout the developing world and helped start an NGO in Uganda when she was a sophomore in college. A second year graduate student in public health, Hayes graduated magna cum laude from Colby College and has spent time working in Haiti and Alaska.
Edith Ismene Nicolaou-Griffin is the student fellow from Davidson College. She is a psychology major with a film and media studies concentration. Her reporting project will take her to Athens, Greece, where she will document untold stories from the youth of Greece as they struggle to deal with a major economic crisis and changing society. Nicolaou-Griffin is the webmaster at The Davidsonian, the university's student newspaper.
Samantha Thornton, a graduate student in multimedia journalism at the University of Miami, will travel to the Democratic Republic of Congo to tell the stories of Congolese women making a positive impact in the fields of public health, education and human rights through multilingual multimedia projects. Prior to pursuing graduate work at the University of Miami, Thornton worked as an assistant photo editor at Food Network Magazine. She earned her undergraduate degree from the University of Tennessee.
Hashim Yonis will earn a masters in educational leadership from Saint Mary's University of Minnesota this year and has been selected to receive a fellowship to support his reporting project. Originally from Somalia, Yonis will return to the country to teach social studies for three months and report on his experience. Yonis previously taught in Ethiopia in 2008 and currently works as an administrative manager in two international high schools in Minneapolis.
Saint Mary's University houses the Under-Told Stories Project, which is directed by our media partner Fred de Sam Lazaro. Under-Told Stories segments are featured regularly on PBS NewsHour nationwide.
Editor's Note: This page was updated on 4.27.12 to include Hashim Yonis.
Editor's Note: This page was updated on 4.30.12 to correct Yonis' country of birth.
This Pulitzer Center Update is a part of:
As Cambodia's Economy Grows, Its Rainforest Disappears
Pulitzer Center alumni
Jennifer is the Pulitzer Center's education coordinator. After graduating from the University of California, Berkeley, she lived in Mexico City. Prior to joining the Pulitzer Center, Jennifer worked...
Africa, Asia, Middle East, North America
Algeria, Cambodia, Congo (DRC), Ethiopia, Greece, South Africa, Thailand, United Arab Emirates
Culture, Education, Environment, Public Health, Youth
Pulitzer Center Update:
General news, Education news
Wake Forest University, High Point University, Guilford College, University of Chicago, Boston University, The George Washington University, Davidson College, University of Miami


Roy's Adaptation Model (RAM) was developed by Sr.Callista Roy.
RAM is one of the widely applied nursing models in nursing practice, education and research.
This is done by assessing behavior and factors that influence adaptive abilities and by intervening to expand those abilities and to enhance environmental interactions.
Mr.NR who was suffering with diabetes mellitus for past 10 years. He developed a diabetic foot ulcer and had to undergo amputation. He was admitted in __ Hospital. Mr. NR was selected for application of RAM in providing nursing care.
According to RAM, nursing process is a problem solving approach for gathering data, identifying the capacities and needs of the human adaptive system, selecting and implementing approaches for nursing care, and evaluation the outcome of care provided.
the first step of the nursing process which involves gathering data about the behavior of the person as an adaptive system in each of the adaptive modes.
the second step of the nursing process which involves the identification of internal and external stimuli that are influencing the person's adaptive behaviors.
Residual- those stimuli whose effect on the situation are unclear.
the forth step of the nursing process which involves the establishment of clear statements of the behavioral outcomes for nursing care.
the sixth and final step of the nursing process which involves judging the effectiveness of the nursing intervention in relation to the behavior after the nursing intervention in comparison with the goal established.
Stable process of ventilation and stable process of gas exchange. RR= 18Bpm.
Chest normal in shape. Chest expansion normal on either side.
Apex beat felt on left 5th inter-costal space mid-clavicular line.
Air entry equal bilaterally. No ronchi or crepitus. NVBS. S1& S2 heard.
Apex beat felt- normal rhythm, depth and rate.
Dorsalis pedis pulsation of affected limp is not palpable.
All other pulsations are normal in rate, depth, tension with regular rhythm.
Cardiac dull ness heard over 3rd ICS near to sternum to left 5ht ICS mid clavicular line.
No abnormal heart sounds. BP- Normotensive. .
Peripheral pulses felt-Normal rate and rhythm, no clubbing or cyanosis.
He is on diabetic diet (1500kcal). Non vegetarian.
Recently his Weight reduced markedly (10 kg/ 6 month).
He has stable digestive process.
He has complaints of anorexia and not taking adequate food.
No abdominal distension. Soft on palpation. No tenderness.
Percussion revealed dullness over hepatic area.
No signs of infections, no pain during micturation or defecation.
Normal bladder pattern. Using urinal for micturation.
Stool is hard and he complaints of constipation.
Sleep pattern disturbed at night due unfamiliar surrounding.
Not following any peculiar relaxation measure.
Like movies and reading. No regular pattern of exercise.
Walking from home to office during morning and evening.
Now, activity reduced due to amputated wound. Mobility impaired.
Pain from joints present. No paralysis.
ROM is limited in the left leg due to wound.
No contractures present. No swelling over the joints.
Patient need assistance for doing the activities.
Left lower fore foot is amputated.
Black discoloration present over the area.
No redness, discharge or other signs of infection.
Walking with the use of left leg is not possible.
Pain form knee and hip joint present while walking.
Dorsalis pedis pulsation, not present over the left leg. Right leg is normal in length and size.
Several papules present over the foot.
All peripheral pulses are present with normal rate, rhythm and depth over right leg.
No pain sensation from the wound site. Relatively, reduced touch and pain sensation in the lower periphery; because of neuropathy. Using spectacle for reading. Gustatory, olfaction, and auditory senses are normal.
Drinks approximately 2000ml of water. Stable intake out put ratio. Serum electrolyte values are with in normal limit. No signs of acidosis or alkalosis. Blood glucose elevated.
He is conscious and oriented.
He is anxious about the disease condition.
Like to go home as early as possible.
Touch and pain sensation decreased in lower extremity. Thinking and memory is intact.
He is on insulin. No signs and symptoms of endocrine disorders, except elevated blood sugar value. No enlarged glands.
He is anxious about changes in body image, but accepting treatment and coping with the situation. He deprived of sexual activity after amputation.
Self esteem disturbed because of financial burden and hospitalization. He believes in god and worshiping Hindu culture.
He was the earning member in the family. His role shift is not compensated. His son doesn't't have any work. His role clarity is not achieved.
Non-healing wound after amputation of great and second toe of left leg- 4 week. A wound first found on the junction between first and second toe-4 month back. The wound was non-healing and gradually increased in size with pus collected over the area.
He first consulted in a local (---) hospital. From there, they referred to ---- medical college; where he was admitted for 1 month and 4 days. During hospital stay great and second toe amputated. But surgical wound turned to non- healing with pus and black colour. So the physician suggested for below knee amputation. That made them to come to ---Hospital, ---. He underwent a plastic surgery 3 week before.
Known case DM for past 10 years. Was on oral hypoglycemic agent for initial 2 years, but switched to insulin and using it for 8 years now. Not wearing foot wear in house and premises.
He had TB attack 10 year back, and took complete course of treatment. Previously, he admitted in ---Hospital for leg pain about 4 year back. . Mother's brother had DM. Mother had history of PTB. He is a graduate in humanities, no special knowledge on health matters.
Mr.NR who was suffering with diabetes mellitus for past 10 years. Diabetic foot ulcer and recent amputation made his life more stressful. Nursing care of this patient based on Roy's adaptation model provided had a dramatic change in his condition. Wound started healing and he planned to discharge on 25th april. He studied how to use crutches and mobilized at least twice in a day. Patient's anxiety reduced to a great extends by proper explanation and reassurance. He gained good knowledge on various aspect of diabetic foot ulcer for the future self care activities.
intact with no ongoing ulcerations.
i. Size of wound decreases to 1x1 cm within 24/4/08.
- Maintain the wound area clean as contamination affects the healing process.
- Follow sterile technique while providing cares to prevent infection and delay in healing.
- Perform wound dressing with Betadine which promote healing and growth of new tissue.
- Do not move the affected area frequently as it affects the granulation tissue formation.
- Monitor for signs and symptoms of infection or delay in healing.
- Administer the antibiotics and vitamin C supplementation which will promote the healing process.
Met: size of wound decreased to less than 1x1 cms.
Partially Met: skin partially intact with no ulcerations.
During hospital stay great and second toe amputated. But surgical wound turned to non- healing with pus and black colour.
Patient will attain maximum possible physical mobility with in 6 months.
iii. He will be self motivated in activities- 20/4/08.
- Provide active and passive exercises to all the extremities to improve the muscle tone and strength.
- Make the patient to perform the ROM exercises to lower extremities which will strengthen the muscle.
- Massage the upper and lower extremities which help to improve the circulation.
- Provide articles near to the patient and encourage performing activities within limits which promote a feeling of well being.
- Provide positive reinforcement for even a small improvement to increase the frequency of the desired activity.
- Measures for pain relief should be taken before the activities are initiated as pain can hinder with the activity.
Met: used crutches correctly on 22/4/08.
Partially Met: walking with minimum support.
Known case DM for past 10 years and on treatment with insulin for 8 years.
3. Anxiety related to hospital admission and unknown Outcome of the disease and financial constrains.
- Allow and encourage the client and family to ask questions. Bring up common concerns.
- Allow the client and family to verbalize anxiety.
- Stress that frequent assessment are routine and do not necessarily imply a deteriorating condition.
He is able to rest quietly.
4. deficient knowledge regarding the foot care, wound care, diabetic diet, and need of follow up care.
Patient will acquire adequate knowledge regarding the t foot care, wound care, diabetic diet, and need of follow up care and practice in their day to day life.
i. Verbalization and demonstration of foot care.
iii. Demonstration of wound care.
- Explain the treatment measures to the patient and their benefits in a simple understandable language.
- Explain about the home care. Include the points like care of wounds, nutrition, activity etc.
Clear the doubts of the patient as the patient may present with some matters of importance.
- Repeat the information whenever necessary to reinforce learning.
Met: Verbalization and demonstration of foot care.
Unmet: Demonstration of wound care.
Black JM, Hawks JH, Keene AM. Medical surgical nursing. 6th ed. Philadelphia: Elsevier Mosby; 2006.
Boon NA, Colledge NR, Walker BR, Hunter JAA. Davidson's principle and practices of medicine. 20th ed. London: Churchill Livingstone Elsevier; 2006.


text:
The 7 Best Multifamily Architects in El Paso, Texas
In 2017, El Paso, Texas, was considered one of the best places to live in the United States because of its low cost of living, high quality of life, top-notch education, and a strong job market. It is also a perfect place to live in, especially for people who love the outdoors.
The list below contains seven of the best multi-family architects in El Paso, Texas. They were selected based on their experience, awards, and portfolio.
root architects
311 Montana Ave. Ste. A2-100, El Paso, Texas 79902
Root architects is an El Paso-based architectural design firm specializing in mixed-use, commercial, and residential projects. It was founded by Rida Asfahani, AIA, LEED APBD+C, in 2010 out of frustration for what was lacking in the development and architecture in El Paso. The firm's members have a collective of forty years of extensive experience, and it is frequently recognized by various organizations and for various awards.
The firm has constructed a wide range of architecture and construction projects, including commercial buildings, K-12, and adaptive reuse. The team is also dedicated to restoring and enhancing the historical fabric of El Paso to help the city evolve and thrive. Root architects is accredited and certified by the American Institute of Architects and the LEED APBD+C. It has also garnered several recognitions and awards from various organizations, including Best Local Architects – El Paso Inc. Magazine (2019), and Merit Award – R.B. Stevens Building (2017).
PSRBB Architects
1810 Wyoming, El Paso, Texas 79903
Headquartered in El Paso, PSRBB Architects is a commercial architecture and planning firm specializing in a wide range of services, including educational, industrial, commercial, residential, and mixed-use communities. It was established in 2005 and is committed to improving the quality of life in the communities it serves. With over sixteen years in the business, it produces top-notch projects and is honored to have served the well-being of the El Paso community.
The firm operates under the leadership of Tomy Razloznik, who holds the role of president. He has been interested in architecture since he was young, so he decided to pursue a career in the industry. Tomy obtained his bachelor's degree in architecture from Texas Tech University in 1976 and joined PSRBB in 1990.
Exigo Architecture
211 N. Florence Suite 204, El Paso, TX 79901
Founded in 2006, Exigo Architecture is a general contracting firm that specializes in multi-family projects, such as apartments, townhouses, and condominiums. It also offers architectural design, planning, and interior services in El Paso and surrounding areas.
With fifteen years of comprehensive experience in the industry, the firm consistently tries to improve and grow as an industry leader that provides high-level consulting services, innovative architectural design, and planning to meet the changing requirements of businesses, institutions, and government entities.
The firm is led by Eugenio Mesta, AIA, CNU-A, who holds a master's degree in architecture from the University of Pennsylvania. The firm is accredited and certified by the American Institute of Architects, Leadership in Energy and Environmental Design Accredited Professional (Building Design and Construction), and the CNU-A.
Liev Architecture
310 N Mesa Street, Ste. 830, Cortez Building, El Paso, Texas 79901
Operating out of its office in El Paso, Texas, Liev Architecture is a general contracting firm that has been in business since 2009. The firm was founded by Carlos Lievanos, and it specializes in architecture and planning services.
The team consists of skilled and experienced architects, engineers, and design professionals passionate about delivering superior architectural design services. The firm has been recognized for its reliable technical expertise and excellence.
Liev Architecture successfully manages projects regardless of their size. Moreover, the firm adopts a highly personalized approach. It takes time to listen and understand its clients' needs to execute their project requirements efficiently. Though it is headquartered in El Paso and San Antonio, it extends its services throughout Texas and New Mexico.
Wright & Dalbin Architects
2112 Murchison Drive, El Paso,TX 79930
With over thirty-five years of comprehensive experience in the industry, WDA is an award-winning full-service architectural firm that provides planning, design, and construction services for commercial, residential, institutional, and educational projects in Texas and New Mexico. WDA has played an integral part in the development and revitalization of many multi-family, and affordable housing complexes.
An American Institute of Architects Award-winning firm, they advocate sustainable and green architecture and incorporate it into designs and solutions. This allows the firm to produce high-performance buildings that add extra value to clients and the environment.
Additionally, WDA has completed over $250 million of building renovations, rehabilitation, and adaptive reuse both for historic and non-historic facilities in the last ten years.
WDA provides complete designs to meet the needs of the existing and new users, creating practical and sustainable architecture indicative of time and place. The firm sets high standards, consistently exceeding expectations for timeliness, cost control, and ingenuity.
Carl Daniel Architects
305 Leon St., El Paso, TX 79901
Carl Daniel Architects is a contracting firm that has provided engineering and architectural services to clients throughout El Paso, Texas. It was founded by Carl V. Daniel Jr. in 1989 and has completed over $400 million in construction projects. Its reputable branding has allowed it to grow and service various markets, including civic, commercial, education, financial, and health care.
Carl V. Daniel Jr. runs the firm up to this day. He has fifty-two years of background in architecture and serves as the lead designer of the firm. He is a registered architect in Texas, Arizona, and New Mexico.
The firm's staff are dedicated and motivated professionals who consistently provide unique and innovative solutions. Carl Daniel Architects is accredited and certified by the American Institute of Architects and National Council of Architectural Registration Boards, LEED AP.
ASA Architects
519 E. Río Grande, El Paso, TX 79902
Established in 1968, ASA Architects is an award-winning and one of the largest architectural firms in Southern New Mexico and West Texas. It offers comprehensive architectural services and specializes in school design, health care, industrial, religious facilities, housing and residential, and public projects.
It has built relationships and trust for over fifty-three years, and since then, it has produced three office locations, Roswell, Las Cruces, and El Paso. The company consists of seasoned professionals and registered architects supported by technical staff experts and intern architects. Its team members are equipped with substantial knowledge, background, and hands-on experience. The firm aspires to provide a positive contribution to the communities it serves by delivering innovative and practical design solutions that exceed the expectations of its clients.


Basic Hierarchical Finite State machine combined with flocking to create a siege tank bio timing push.
Monthy win rate of Tommy Fang over last 3 years compared to 4 bots with best ELO.
Win rate of Tommy Fang against all the opponents with at least 50 mutual games.


text:
Explore the Nexus
Species & Spaces
Markets & Materials
People & Professions
Engagement & Involvement
Collaboration & Communication
Programme Advisory Committee
Project communications
The @justsaysinmice problem goes far deeper than bad science reporting
Guest Blog by Nicole C Nelson
We are delighted to feature this guest blog on mice models in animal research from Nicole C. Nelson. Nicole is a professor in the School of Medicine and Public Health at the University of Wisconsin — Madison, and the author of the 2018 book Model Behavior published by The University of Chicago Press
The account is the science nerd equivalent of adding "in bed" to the end of any sentence for a laugh: "Low-protein, high carb diet could help stave off dementia … in mice." "Ketamine may relive depression by repairing damaged brain circuits … in mice."
In the past month, the Twitter account @justsaysinmice has gained over fifty thousand followers by doing exactly what its name promises — tweeting "IN MICE" in response to current science news headlines. The account is the science nerd equivalent of adding "in bed" to the end of any sentence for a laugh: "Low-protein, high carb diet could help stave off dementia … in mice." "Ketamine may relive depression by repairing damaged brain circuits … in mice." You get the idea. The tweets are amusing and point to a real issue in science: Over-hyped statements that make scientific findings look closer to clinical application than they actually are. But the account attributes that problem to the wrong source. It's not just that science journalists don't know how to talk about science; scientists themselves don't know either.
In a recent article on Medium, scientist James Heathers blames the sensationalized news headlines that he critiques with his @justsayinmice account on sloppy science news reporting. What really "grinds his gears," Heathers writes, is when journalists report on animal research in a way that makes it seem as though the findings are directly relevant to humans. Eliding that difference, he writes, "is like pointing at a pile of two-by-fours and a bag of tenpenny nails and calling it a cottage."
Heathers is right to call out some particularly egregious reporting tactics that seem designed to mislead, such as headlines that talk about people when the article actually describes animal research. But the problem goes far deeper than bad science reporting. As an ethnographer who spent years in mouse behavior genetics laboratories, I have watched scientists themselves struggle to find ways of talking about the relationship between mice and humans in their own experiments.
Take for example the elevated plus maze (above), a behavioral test for mice widely used in developing new drugs to treat anxiety. The test uses a simple maze in the shape of a plus sign. Two arms of the plus sign are enclosed by high walls to create narrow corridors, and the other two are open ledges. Scientists place a mouse at the center of the maze and then measure how much time it spends in the "open" versus the "closed" arms. The more time a mouse spends in the open areas of the maze, the less anxious it is said to be.
The scientists I studied were painfully aware that a mouse who refused to venture out into the open arms of a plastic maze was not directly comparable to a person suffering from an anxiety disorder. They were quick to point out that we have no way of knowing what a mouse in that situation was feeling, and that there was plenty of experimental evidence to suggest that the test captured some facets of human anxiety but missed others.
The verbal shorthand that they used to convey the gap between mouse and human was to refer to the maze as a "test of anxiety-like behavior." The "anxiety-like" was critical for these scientists — it reminded them that what they were studying was not anxiety, but something like it. Exactly how their animal models were unlike human anxiety was not yet fully known, and so the phrase remained vague. These scientists had similarly cumbersome ways of speaking about "tests of depression-related phenotypes" or "behaviors relevant to schizophrenia." They used these phrases almost ritualistically, even in casual conversations and in the private spaces of the laboratory. Newcomers to the laboratory, such as myself, were speedily corrected when they slipped into the simplification of referring to the elevated plus maze as a "test of anxiety."
A human version of the elevated plus maze is available to view on YouTube. Note the description of the maze as a tool for studying "human anxiety-related behavior."
This vocabulary for communicating uncertainty worked well in groups of like-minded behavioral scientists, but fell apart quickly outside of it. Even fellow scientists from other disciplines were confused about why their seemingly pedantic colleagues insisted on calling mouse behavior "anxiety-like." The situation was even worse when I watched scientists talking about their research to journalists, who saw the scientists' cautionary phrases as mere jargon.
My research in animal behavior genetics laboratories led me to conclude that scientists need new, more sophisticated vocabularies for expressing degrees of certainty and uncertainty in their research. Vague terms such as "anxiety-like" are very much like the "weasel words" that science journalists get critiqued for using — Ketamine may relieve depression, low-protein diets could help stave off dementia. Both types of phrases give little information about how much distance there is between mouse and human, or how much confidence readers should place in these results.
The problem of how to talk about uncertainty in science is one that's getting worse, not better. In recent years, the vocabulary that many scientists use to express how confident they are in their findings — significance testing and p-values — have come under attack. Critics point to important problems with how p-values are used in science today, but the fact remains that p-values are one of the few shared vocabularies that scientists have for expressing degrees of confidence in their findings.
It is easy to blame bad reporting for making scientific findings seem more certain and relevant than they actually are, but this ignores the imprecision in how scientists themselves talk about translational research. Heathers claims that adding "in mice" to science news headlines is an easy "fix" to the problem of animal research being taken out of context. This move fixes one problem, but leaves a deeper one unresolved. Even when a headline clearly states that the original study was done in mice, one person's impression of how close that study is to clinical application is likely to be very different another person's. We need better scientific vocabularies that will help readers calibrate their sense of certainty. Solving that problem must begin with scientists, not science journalists.
Guest Blogger Nicole C Nelson considers how an amusing Twitter account is highlighting a real issue in the communication of science.
Openness & Transparency
Collaborating institutions
AnNex, c/o Fiona French,
University of Exeter Amory Building,
Rennes Drive, Exeter EX4 4RJ, UK
Environmental Ethics Statement


text:
Q: Why my react native app crashes on Android after 5-10 minutes in background state? On android my react native app crashes when it remains 5-10 minutes in background and after that i open it again.
Can anyone please tell me why it's crashing?

redpajama_set_name: RedPajamaStackExchange


Thanks to Lead Nurse Africa for the initiative, It was a conference that leaves me with it's enriching impact daily not only in nursing but in all facets of life.I am glad to be a part of it because it was worth more than the price.
I must admit that I am impressed with this conference and sincerely hope it waxes stronger.
I'd like to appeal that invitation for such conferences be open to a larger number of Nurses.


text:
Protest updates: Madison wraps up week of events; protester says it's 'the beginning of a revolution'
Across America, protesters are demonstrating against the death of George Floyd, a black man who died with his neck pinned under the knee of since-fired Minneapolis police officer Derek Chauvin for 8 minutes and 46 seconds. Floyd called out for his mother. He gasped the words: "I can't breathe." He was accused of trying to buy a pack of cigarettes with a counterfeit $20 bill.
The Milwaukee Journal Sentinel is covering local demonstrations and fallout and will update this story throughout the day.
See Friday's full coverage here. Some highlights: A new mural honored Floyd. Milwaukee's mayor spoke against using rubber bullets and tear gas on protesters. There are new concerns about Boogaloo boys.
Some background:
Milwaukee has a long and proud history of civil rights activism against police brutality and racial inequity. In 1967, demonstrators took to the streets for 200 consecutive days, marching until Milwaukee passed one of the strongest fair housing laws in the U.S. Yet, it remains one of the country's most segregated metro areas.
How far has Milwaukee come since the 1967 fair housing marches?
Are the protests peaceful? What about unrest?
What legacy will the marchers leave?
What do community leaders have to say about the roots of racism against black people?
10:23 p.m.: Madison wraps up week of events; protester says it's 'the beginning of a revolution'
Madison organizations are wrapping up their week of action, "In Defense of Black Life," demanding justice against police brutality after the death of George Floyd in Minneapolis on May 25.
From last Saturday to this Saturday, Madison has not let up on the protests, which have taken place every night and lasted until the early hours of the morning.
And there's been plenty of contrast in the downtown area in what each night looked like. In just five days, State Street went from a scene of total destruction to the picture of community — covered in bright murals, and no altercations with law enforcement.
While protesters still gather at the Capitol on Saturday night, organizers took to Facebook to discuss political education and action.
"We should not use policing, prisons and punishment to solve social issues… We should be investing in reformative, life-building and life-affirming solutions," said Morathi Adams of Freedom, Inc. "We live in a society where black life is not valued because of policing structures, jail structures. We have to disrupt those systems."
Over the course of the week, organizers have compared Floyd's death to that of Tony Robinson's in 2015, when a police officer shot and killed the unarmed black teenager after an altercation. Robinson's death rocked the capital city and spurred a number of large protests.
Bianca Gomez compared Saturday's protest to those that occurred after Robinson's death.
"They said it was peaceful because it wasn't threatening to whiteness," Gomez said. "Five years ago we were not seen as peaceful."
CJ, a local activist who's been fighting for black rights in Madison for a decade, led chants on the steps of the Capitol building Saturday evening.
He said this can't be the last day of protests, even though the the week of action is coming to a close.
"This is not the end of a weeklong movement — this is the beginning of a revolution. I'm not going anywhere," he said. "The movement never ended.
"We thought things were equal when they weren't and here we are again. I'm going to make sure my children don't have to fight this again."
—Allison Garfield
10:07 p.m.: Hundreds march against officer who's killed 3
Several hundred people marched through Wauwatosa on Saturday demanding the police department there fire an officer who's killed three people in the line of duty.
During the march, protesters repeatedly chanted the names of those who have been fatally shot by officer Joseph Mensah: Antonio Gonzalez, Jay Anderson Jr. and Alvin Cole.
Mensah was cleared of wrongdoing in the first two shootings, which happened in 2015 and 2016, but remains under investigation for the February shooting of Cole, who was 17.
Cole's older sister, Taleavia Cole, led protesters on a three-mile march from the intersection of 76th and Burleigh streets to a parking lot outside Mayfair Mall, where her brother was shot. There, organizers recited a phone number for the Wauwatosa Police Department and marchers flooded the phone lines to demand Mensah be fired.
Taleavia Cole and her mother, Tracy, addressed the crowd before the march. They said Alvin Cole came from a good, stable family and planned to join his sister at Jackson State University this fall.
"Alvin wasn't brought up in a broken home," Tracy Cole said. "The system is broken."
— Elliot Hughes
8 p.m.: Bucks will hold public protest march on Sunday
The Milwaukee Bucks will hold a public protest march in support of social justice on Sunday at 1 p.m. on the plaza in front of Fiserv Forum.
The march will include players, coaches, ownership, management and staff. Several Bucks players, including reigning NBA MVP Giannis Antetokounmpo, took part in a protest march Saturday evening.
There will be public remarks at the intersection of Juneau Ave. and Vel R. Phillips Ave., and then the march will follow.
- Ben Steele
6:12 p.m.: Giannis Antetokounmpo, Sterling Brown and other Bucks players join Milwaukee protest
Several Milwaukee Bucks players, including reigning NBA most valuable player Giannis Antetokounmpo, joined local activist Frank Nitty as protesters marched down 27th Street.
Antetokounmpo was joined by Bucks teammates Sterling Brown, Donte DiVincenzo, Brook Lopez, two-way player Frank Mason II and Thanasis Antetokounmpo, Giannis' brother.
The group wore identical gray T-shirts with the slogan "I can't breathe" printed on the front. All the players wore masks and gloves due to the ongoing coronavirus pandemic.
"I want my kid to grow up here in Milwaukee, and not to be scared to walk in the streets," Antetokounmpo said. "I don't want my kid to have hate in his heart."
Read the full story.
— Ben Steele
5 p.m.: Man arrested during protest in Milwaukee speaks out
The 28-year-old man who was taken to the ground by Milwaukee police and arrested during a protest earlier last week is speaking out.
"I've not generally been an activist but I saw what happened to George Floyd and I wanted to get out and support my community and stand with them in solidarity. Black lives matter," said Cameron Murdoch in a video released Saturday.
"I never expected that I would be assaulted by the police with a knee on my neck," he said. "I'm saddened that participating in a safe protest during the day made me the victim of police brutality."
Murdoch was arrested Tuesday during a demonstration at 6th Street and McKinley Avenue in downtown Milwaukee. The Milwaukee Police Department has said it is reviewing officers' use of force during the arrest.
In the video, Murdoch said he wants to hold police accountable for how they treated him and push for new policies and standards. He is being represented by attorneys E. Edgar Lin and Drew DeVinney.
"Mr. Murdoch's constitutional rights were violated and he will be pursuing any available claims to the full extent of the law," the attorneys said in a news release.
The nationwide protests against police brutality were prompted by the death of George Floyd, who died after a Minneapolis police officer pressed a knee into his neck for more than eight minutes as Floyd and bystanders pleaded with the officer to stop.
—Ashley Luthern
4:30 p.m.: Thousands gather in Shorewood and Whitefish Bay
Roughly 1,500 people came to Atwater Park in Shorewood Saturday afternoon to protest police brutality and racial injustice.
Just two miles north, in Whitefish Bay, more than 1,000 protesters gathered for a separate demonstration outside Whitefish Bay Village Hall. Protesters laid in the street for nine minutes, which is nearly the amount of time Minneapolis police officer Derek Chauvin left his knee on 46-year-old George Floyd's neck, killing him and sparking more than a week of protests across the country.
The Shorewood protest was organized by students from Shorewood High School. One of those students, 14-year-old Bella Busby, recounted the 2014 killing of 12-year-old Tamir Rice, who was shot and killed by a Cleveland police officer who thought the boy's toy gun was real.
"There are countless stories that have ended the same way, with black people being murdered for something that could have ended with a ticket," she said.
The Shorewood School District has grappled with many race-related controversies of its own, prompting the district to hire its first equity director, Sam Coleman, who spoke at the rally.
Coleman said the protest was organized to "resist against the state-sanctioned and systemically-reinforced violence against black bodies."
"We have to declare that black lives matter today and every day," he said.
State Rep. David Bowen told the crowd that the state Legislature, Congress and city officials are blocking policies that he said would reduce police violence toward black communities.
While he said some people might feel "antsy" from some of the protesters' actions, like driving on the grass and sidewalk in Shorewood last weekend, he said civil disobedience is needed to create change in policing policy.
"If it's not making you uncomfortable, it's not working," he said.
- Jeff Rumage
2:37 p.m. Cedarburg event back on; this time it's Black Lives Matter
Remember that Peace in the Park event canceled Saturday in Cedarburg over the lack of insurance liability? A new event now appears to be taking its place.
A Black Lives Matter protest is now scheduled for 3 p.m. in Cedar Creek Park. The announcement being circulated on Facebook says the event was "re-created" after the organizer of the original event was "intimidated" by Cedarburg government into canceling.
Kayla Stoflet-Santillanes said she canceled her anti-racism event because she couldn't afford the liability insurance required by the city's permit if the crowd grew beyond 250 people. The estimate she obtained as of Friday would have cost $15,000. (See below.)
— Annysa Johnson
2:20 p.m. City blocks traffic in area of frequent protests
In an effort to limit vehicle traffic in one of the areas of frequent protests over the last week, the city of Milwaukee is blocking access near North Martin Luther King Drive and West Center Street through Sunday, according to the Department of Public Works.
DPW issued a statement Saturday saying Center Street would be blocked in both directions about a block from North Martin Luther King Drive as of 9:30 a.m. Saturday.
Beginning at 3 p.m., all north-south traffic of North Martin Luther King Drive would be blocked between West Center Street and West North Avenue. And vehicles would not be able to turn from North MLK Drive onto West Center Street.
1:30 p.m.: Dontre Hamilton documentary free on YouTube
"The Blood Is at the Doorstep," a documentary about the death of Dontre Hamilton at the hands of a Milwaukee police officer and the movement that tragedy spawned, is now showing for free on YouTube.
Producer-director Erik Ljung said via email Friday that the 2017 movie has been uploaded to YouTube for free for a limited time "to make it as accessible as possible."
Hamilton was shot 14 times by a police officer in Red Arrow Park in downtown Milwaukee in 2014. "The Blood Is at the Doorstep" tells his story, what happened that day, and the aftermath for Hamilton's family and for the city.
The movie's being made available to a wider audience, Ljung wrote, to help with the continuing conversation about police violence and community engagement in making change happen.
"The Blood Is at the Doorstep" is one of several movies about the black experience in America that have made available for free viewing online since protests proliferated in Milwaukee and around the world following the death of George Floyd, a black man who died with his neck pinned under the knee of a Minneapolis police officer.
— Chris Foran
1:05 p.m.: MPS' Posley offers resources for talking to your children about race
Milwaukee Public Schools Superintendent Keith Posley on Saturday called on the city, state and nation to hear the voices of young people and "finally face the difficult history that we have avoided for so long."
And he offered a number of resources families can use to talk to their children about race.
"I am always humbled and inspired by our students' resilience, intelligence, and fortitude," said Posley, whose district serves almost 75,000 students, most of them low-income children of color.
"My hope rests with all of our children, and their capacity to move past the divisions, racism, and bigotry that have marked our country since long before its founding. I share their vision and belief in a just world where every person, of every race, belongs and is honored and celebrated."
11:01 a.m.: Cedarburg peace event canceled over insurance costs
An anti-racism event scheduled at a Cedarburg park Saturday was canceled after the organizer could not obtain the liability insurance required by the city's permit if the crowd grew beyond 250 people.
Kayla Stoflet-Santillanes of Cedarburg said there was no way to accurately gauge the size of the crowd that might turn out for the event she'd dubbed Peace in the Park, and the only insurance estimate she could obtain as of Friday would have cost $15,000.
"I'm disappointed, but ultimately I think it's going to take place at a later date," said Stoflet-Santillanes, who is continuing to search for insurance. "That's my hope."
Stoflet-Santillanes said about 170 people were expected to attend at last count, and that she'd had an overwhelmingly positive response from local businesses. She said the Cedarburg Police Department had been helpful, waiving the permit fee and agreeing not to charge her for the cost of city employees who might be deployed as a result of the event. But the insurance, she said, was an insurmountable hurdle, at least as of Friday.
She's still hoping to sell the 50 T-shirts that were printed for the event by a black-owned West Allis company. They feature a black peace sign with the words: Peace in the Park … Anti-racism, Pro-Justice … Cedarburg 6.6.20. More information will be available soon at the Cream City Print Lounge.
8:07 a.m.: MPS board calls on police to denounce use of tear gas, rubber bullets; vows dialogue in district
The Milwaukee Public Schools board of directors called on the Milwaukee Police Department to "publicly renounce the use of tear gas, rubber bullets, and other aggressive measures against peaceful protesters exercising their first amendment rights."
The board said directors would be working with Superintendent Keith Posley and his administration to engage the district in talks with MPS students around the issues of race and racism.
"We are committed to the emotional and physical safety of Black students and other youth of color," the board said in a statement issued late Friday, on the eighth day of protests across the region following the death of George Floyd.
"It means that our schools and classrooms must be safe spaces for dialogue, listening to students, and support on the issues raised by the Black Lives Matter movement. We have a responsibility to end the school-to-prison pipeline and ensure that the curriculum is anti-racist and culturally relevant."
The board said it stands with black youth and their communities in opposing "all racist systems of oppression including laws, policies, and government actions."
"The disproportionate rates of suspensions and expulsions, mass incarceration, the war on drugs, unjust policing, voter suppression, and the underfunding of public schools, as well as, structural policies like redlining, gentrification, employment discrimination, and more— all have disastrous consequences on Black communities," it said.
MPS, which serves about 75,000 students, mostly low-income children of color, has budgeted funds this year to expand its ethnic studies and Black Lives Matter programming.
1 a.m.: Tense moments aside, eighth day of Milwaukee protests is peaceful
It was mostly peace and calm on the eighth day of protests against police brutality in Milwaukee.
But that doesn't mean there weren't tense moments.
One group of local activists protesting the death of George Floyd by Minneapolis police began their march in Humboldt Park on Friday and completed their loop just before 10:30 p.m., according to a livestream of the event.
The protesters cheered for the event organizers, who thanked everyone for walking a reported 16 miles, and everyone took a moment to howl at the full moon in celebration.
Another march of some 200 protesters, led by local activist Frank Nitty, traveled down West Wisconsin Avenue before heading to the city's south side.
The group came face to face with dozens of Milwaukee police officers when the marchers stopped shortly after 11 p.m. in front of the Milwaukee Police Department's District 2 station at 245 W. Lincoln Ave.
The protesters chanted, "Kneel with us," while one or two in the crowd stepped forward to direct comments at the police officers lined in front of the station.
None of the officers appeared to respond.
Khalil Coleman, one of the leaders of the march, helped defuse the tension from the standoff by handing his bullhorn to a 4-year-old girl, who belted out, "Black lives matter," prompting cheers from the crowd of protesters.
Later, two protesters told Nitty that marching was "the best way" to spend their 21st wedding anniversary. Nitty brought them to the front of the crowd so other protesters could congratulate them and they could share their story.
— Dan Bice