MIT to develop a robotic Swiss Army knife.
A recent MIT squad is working on a robotic device. The device provides the opportunity in becoming the most convenient model ever. Identified with they since the "this equal of a Swiss Army knife. This consists of a succession associated with tiny module chain equally created using different types of viewpoint this is proven to from the concatenation within many shapes. Their unique shape-changing capacity could result in coming of robots this dynamically alters for doing their task properly.
Still, the Milli-motion robots can do their task just by converting alone into the instrument they need. The application also increases the milli-motein the chance of at one point transforming into an approximately complete engine.
The team checking out researcher postdoctoral internet affiliate Kenneth Cheung labels this notion 'programmable matter'. Preferably, this term would love to reach is actually a tool in which can modify to be regardless of what is inside the time.
This gadget might be composed of fewer chains involving modules. That may seem similar to the additional wormlike robotic invention. Some people think of it as the electropermanent engine and also its particular rationale is just like scrap yard electromagnets employed to raise vehicles.


Evolution Dance Academy was previously known as Edenbridge School Of Dance and Scamps dance and has been merged in 2014 to join as one dance school. We are continuing to grow and with it grows a reputation of running fun dance classes where children can learn to improve their dance skills in a relaxed environment. Not only do we hope our children can learn dance skills, but they can improve in confidence and make strong friendships with their classmates. We run classes in Edenbridge, Lingfield, and Sevenoaks.
All our teachers are trained, experienced and have current CRB/DBS checks. We are a member of the IDTA and follow that syllabus in class. Our staff do have experience in other dance syllabi giving them good knowledge and a way to include other dance exercises into the lessons to improve on their students' knowledge.
During the school holidays we like to keep all our children entertained and be able to continue to enjoy dance. Therefore, we offer a variety of different workshops to our students that give them opportunity to try different things. Please click on our latest news page for more information.
We run various different types of dance classes throughout the week that can be found on our 'Dance Styles' pages. We encourage children to take up whatever form of dance inspires them. However, for any aspiring dancers we encourage them to take at least one ballet class a week because this is the core foundation of dance. Private classes are also offered to those students who are keen to improve their skills. We keep up to date with what is currently popular and run a variety of classes. With the increasing popularity of singing, dancing and acting combined, and one our members of staff having a background in Musical Theatre we have a popular and ever increasing musical theatre class running. Our pre-school Tiny Tots class is designed to encourage our younger members to learn how to use their bodies and gain a basic knowledge of dance along to music that they know and love. All our music is either syllabus related or in keeping with what is popular at the time.
Our dance classes include ballet, tap, street dance, Irish, modern, contemporary and musical theatre. click on the picture below for a timetable of all our lessons!


text:
Last 3 years (5)
Over 3 years (5)
Infection Control & Hospital Epidemiology (9)
British Journal of Nutrition (1)
Society for Healthcare Epidemiology of America (SHEA) (9)
Nestle Foundation - enLINK (1)
Routine saliva testing for the identification of silent COVID-19 infections in healthcare workers
Kevin Zhang, Affan Shoukat, William Crystal, Joanne M. Langley, Alison P. Galvani, Seyed M. Moghadas
Journal: Infection Control & Hospital Epidemiology / Accepted manuscript
Published online by Cambridge University Press: 11 January 2021, pp. 1-17
Current COVID-19 guidelines recommend symptom-based screening and regular nasopharyngeal (NP) testing for healthcare personnel in high-risk settings. We sought to estimate case detection percentages with various routine NP and saliva testing frequencies.
Simulation modelling study.
We constructed a sensitivity function based on the average infectiousness profile of symptomatic COVID-19 cases to determine the probability of being identified at the time of testing. This function was fitted to reported data on the percent positivity of symptomatic COVID-19 patients using NP testing. We then simulated a routine testing program with different NP and saliva testing frequencies to determine case detection percentages during the infectious period, as well as the pre-symptomatic stage.
Routine bi-weekly NP testing, once every two weeks, identified an average of 90.7% (SD: 0.18) of cases during the infectious period and 19.7% (SD: 0.98) during the pre-symptomatic stage. With a weekly NP testing frequency, the corresponding case detection percentages were 95.9% (SD: 0.18) and 32.9% (SD: 1.23), respectively. A 5-day saliva testing schedule had a similar case detection percentage as weekly NP testing during the infectious period, but identified about 10% more cases (mean: 42.5%; SD: 1.10) during the pre-symptomatic stage.
Our findings highlight the utility of routine non-invasive saliva testing for frontline healthcare workers to protect vulnerable patient populations. A 5-day saliva testing schedule should be considered to help identify silent infections and prevent outbreaks in nursing homes and healthcare facilities.
National Surveillance of Methicillin-Resistant Staphylococcus aureus Bloodstream Infections in Canadian Acute-Care Hospitals
Linda Pelude, Jennifer Campbell, Suzanne Bakai-Anderson, Pat Bedard, Jeannette Comeau, Joan Durand, John Embil, Joanne Embree, Gerald Evans, Charles Frenette, Allana Ivany, Kevin Katz, Pamela Kibsey, Joanne Langley, Bonita Lee, Jerome Leis, Allison McGeer, Jennifer Parsonage, Donna Penney, Anada Silva, Jocelyn Srigley, Paula Stagg, Jen Tomlinson, Joseph Vayalumkal, Connie Gittens-Webber, Stephanie Smith, CNISP PHAC
Journal: Infection Control & Hospital Epidemiology / Volume 41 / Issue S1 / October 2020
Published online by Cambridge University Press: 02 November 2020, pp. s72-s73
Background: Bloodstream infections (BSIs) due to methicillin-resistant Staphylococcus aureus (MRSA) are important causes of morbidity and mortality in hospitalized patients. Long-term national MRSA BSI surveillance establishes rates for internal and external comparison and provide insight into epidemiologic, molecular, and resistance trends. Here, we present and discuss National MRSA BSI incidence rates and trends over time in Canadian acute-care hospitals from 2008 to 2018. Methods: The Canadian Nosocomial Infection Surveillance Programme (CNISP) is a collaborative effort of the Association of Medical Microbiology and Infectious Disease Canada and the Public Health Agency of Canada. Since 1995, the CNISP has conducted hospital-based sentinel surveillance of MRSA BSIs. Data were collected using standardized definitions and forms from hospitals that participate in the CNISP (48 hospitals in 2008 to 62 hospitals in 2018). For each MRSA BSI identified, the medical record was reviewed for clinical and demographic information and when possible, 1 blood-culture isolate per patient was submitted to a central laboratory for further molecular characterization and susceptibility testing. Results: From 2008 to 2013, MRSA BSI rates per 10,000 patient days were relatively stable (0.60–0.56). Since 2014, MRSA BSI rates have gradually increased from 0.66 to 1.05 in 2018. Although healthcare-associated (HA) MRSA BSI has shown a minimal increase (0.40 in 2014 to 0.51 in 2018), community-acquired (CA) MRSA BSI has increased by 150%, from 0.20 in 2014 to 0.50 in 2018 (Fig. 1). Laboratory characterization revealed that the proportion of isolates identified as CMRSA 2 (USA 100) decreased each year, from 39% in 2015 to 28% in 2018, while CMRSA 10 (USA 300) has increased from 41% to 47%. Susceptibility testing shows a decrease in clindamycin resistance from 82% in 2013 to 41% in 2018. Conclusions: Over the last decade, ongoing prospective MRSA BSI surveillance has shown relatively stable HA-MRSA rates, while CA-MRSA BSI rates have risen substantially. The proportion of isolates most commonly associated with HA-MRSA BSI (CMRSA2/USA 100) are decreasing and, given that resistance trends are tied to the prevalence of specific epidemic types, a large decrease in clindamycin resistance has been observed. MRSA BSI surveillance has shown a changing pattern in the epidemiology and laboratory characterization of MRSA BSI. The addition of hospitals in later years that may have had higher rates of CA-MRSA BSI could be a confounding factor. Continued comprehensive national surveillance will provide valuable information to address the challenges of infection prevention and control of MRSA BSI in hospitals.
Funding: None
Disclosures: None
Variability in Antimicrobial Use Among Hospitals Participating in the Canadian Nosocomial Infection Surveillance Program
Wallis Rudnick, Linda Pelude, Michelle Science, Daniel J.G. Thirion, Jeannette Comeau, Bruce Dalton, Johan Delport, Rita Dhami, Joanne Embree, Yannick Émond, Gerald Evans, Charles Frenette, Susan Fryters, Greg German, Jennifer Grant, Jennifer Happe, Kevin Katz, Pamela Kibsey, Justin Kosar, Joanne Langley, Bonita E. Lee, Marie-Astrid Lefebvre, Jerome Leis, Susan McKenna, Allison McGeer, Heather Neville, Anada Silva, Andrew Simor, Kathryn Slayter, Kathryn Suh, Alena Tse-Chang, Karl Weiss, John Conly, CNISP PHAC
Published online by Cambridge University Press: 02 November 2020, p. s509
Background: The association between antimicrobial use (AMU) and emergence of antimicrobial resistance is well documented. The Canadian Nosocomial Infection Surveillance Program (CNISP) has conducted sentinel surveillance of AMU at participating Canadian hospitals since 2009 resulting in the largest pan-Canadian hospital database of dispensed antimicrobials. Objectives: Describe interhospital variability of AMU across Canada. Methods: Hospitals submit annual AMU data based on patient days (PD). Antimicrobials were measured in defined daily doses (DDD) for adults using the WHO Anatomical Therapeutic Chemical (ATC) system. The AMU data among pediatric patients have been available since 2017 using days of therapy (DOT). Surveillance includes systemic antibacterial agents (J01 ATC codes), oral metronidazole, and oral vancomycin. AMU was assessed using quintiles, interquartile ranges (IQR), and relative IQRs (upper- and lower-quartile values divided by the median). Results: Between 2009 and 2018, 20–26 hospitals participated in adult surveillance each year (35 teaching hospitals and 3 nonteaching hospitals participated in ≥1 year). Over this period, overall AMU decreased by 13% at participating adult hospitals from 645 to 560 DDD per 1,000 PD. AMU varied substantially between hospitals, but this variability decreased over time (Fig. 1). In 2009, the IQRs for overall AMU spanned 309 DDD per 1,000 PD, and in 2018 it spanned only 103 DDD per 1,000 PD. This decrease in variability was due to large decreases in use among hospitals with high use in 2009–2010. Among hospitals in the highest use quintile in 2009–2010, AMU decreased, on average, 44 DDD per 1,000 PD each year. Among hospitals in the lowest use quintile in 2009–2010, AMU increased, on average, 6 DDD per 1,000 PD each year. In 2018, antibiotics with the largest absolute IQR variability were cefazolin (61–113 DDD per 1,000 PD), piperacillin-tazobactam (32–64 DDD per 1,000 PD), and vancomycin (24–49 DDD per 1,000 PD). Among antibiotics with ≥1 DDD per 1,000 PD, antibiotics with the largest relative IQR variability were tobramycin (0.3–6 DDD per 1,000 PD), cefadroxil (0.08–9 DDD per 1,000 PD), and linezolid (0.2–3 DDD per 1,000 PD). In 2018, the IQR for overall pediatric AMU (n = 7 teaching hospitals) was 426–581 DOT per 1,000 PD. Antibiotics with the largest IQRs were vancomycin (0.6–58 DOT per 1,000 PD), cefazolin (33–88 DOT per 1,000 PD), and tobramycin (3–57 DOT per 1,000 PD). Among antibiotics with ≥1 DOT per 1,000 PD in 2018, antibiotics with the largest relative IQRs were tobramycin (3–57 DOT per 1,000 PD), cefuroxime (1–6 DOT per 1,000 PD), and amoxicillin (8–42 DOT per 1,000 PD). Conclusions: There is wide variation in overall antibiotic use across hospitals. Variation between AMU at adult hospitals has decreased between 2009 and 2018; in 2018, antibiotics with the largest IQRs were cefazolin and piperacillin-tazobactam. Benchmarking AMU is crucial for informing antimicrobial stewardship efforts.
Funding: CNISP is funded by the Public Health Agency of Canada.
Disclosures: Allison McGeer reports funds to her institution from Pfizer and Merck for projects for which she is the principal investigator. She also reports consulting fees from Sanofi-Pasteur, Sunovion, GSK, Pfizer, and Cidara.
Epidemiological and Molecular Characterization of Clostridioides difficile Infection in Canadian Outpatient Settings, 2015–2019
CNISP PHAC, Anada Silva, Nisha Thampi, Kelly Baekyung Choi, Linda Pelude, Charles Frenette, Blanda Chow, undefined Control, Bonita Lee, s Hospital, Geoffrey Taylor, Susy Hota, Jennie Johnstone, Gerald Evans, Yves Longtin, Ian Davis, Joanne Langley, Jeannette Comeau, Michelle Science, Alice Wong, Dominik Mertz, Kathryn N. Suh, Pamela Kibsey, Jun Chen Collet, Jocelyn Srigley, Ghada Al-Rawahi, Paula Stagg, Jessica Minion, Appelle Health Region, Guanghong Han
Published online by Cambridge University Press: 02 November 2020, pp. s472-s473
Background: Healthcare services are increasingly shifting from inpatient to outpatient settings. Outpatient settings such as emergency departments (EDs), oncology clinics, dialysis clinics, and day surgery often involve invasive procedures with the risk of acquiring healthcare-associated infections (HAIs). As a leading cause of HAI, Clostridioides difficile infection (CDI) in outpatient settings has not been sufficiently described in Canada. The Canadian Nosocomial Infection Surveillance Program (CNISP) aims to describe the epidemiology, molecular characterization, and antimicrobial susceptibility of outpatient CDI across Canada. Methods: Epidemiologic data were collected from patients diagnosed with CDI from a network of 47 adult and pediatric CNISP hospitals. Patients presenting to an outpatient setting such as the ED or outpatient clinics were considered as outpatient CDI. Cases were considered HAIs if the patient had had a healthcare intervention within the previous 4 weeks, and they were considered community-associated if there was no history of hospitalization within the previous 12 weeks. Clostridioides difficile isolates were submitted to the National Microbiology Laboratory for testing during an annual 2-month targeted surveillance period. National and regional rates of CDI were stratified by outpatient location. Results: Between January 1, 2015, and June 30, 2019, 2,691 cases of outpatient-CDI were reported, and 348 isolates were available for testing. Most cases (1,475 of 2,691, 54.8%) were identified in outpatient clinics, and 72.8% (1,960 of 2,691) were classified as community associated. CDI cases per 100,000 ED visits were highest in 2015, at 10.3, and decreased to 8.1 in 2018. Rates from outpatient clinics decreased from 3.5 in 2016 to 2.7 in 2018 (Fig. 1). Regionally, CDI rates in the ED declined in Central Canada and increased in the West after 2016. Rates in outpatient clinics were >2 times higher in the West compared to other regions. RT027 associated with NAP1 was most common among ED patients (26 of 195, 13.3%), whereas RT106 associated with NAP11 was predominant in outpatient clinics (22 of 189, 11.6%). Overall, 10.4% of isolates were resistant to moxifloxacin, 0.5% were resistant to rifampin, and 24.2% were resistant to clindamycin. No resistance was observed for metronidazole, vancomycin, or tigecycline. Compared to CNISP inpatient CDI data, outpatients with CDI were younger (51.8 ± 23.3 vs 64.2 ± 21.6; P < .001), included more females (56.4% vs 50.9%; P < .001), and were more often treated with metronidazole (63.0% vs 56.1%; P < .001). Conclusions: For the first time, CDI cases identified in outpatient settings were characterized in a Canadian context. Outpatient CDI rates are decreasing overall, but they vary by region. Predominant ribotypes vary based on outpatient location. Outpatients with CDI are younger and are more likely female than inpatients with CDI.
Disclosures: Susy Hota reports contract research for Finch Therapeutics.
Central-line–Associated Bloodstream Infections Among Adult Intensive Care Unit Patients in Canadian Hospitals, 2011–2018
Wallis Rudnick, Lynn Johnston, Jocelyn A. Srigley, Jun Chen Collet, Jeannette Comeau, Chelsey Ellis, Charles Frenette, Bonita E. Lee, Joanne M. Langley, Marie-Astrid Lefebvre, Allison McGeer, Jennifer Parsonage, Donna Penney, Michelle Science, Anada Silva, Stephanie W. Smith, Kathryn N. Suh, Linda Pelude, CNISP PHAC
Background: Nosocomial central-line–associated bloodstream infections (CLABSIs) are an important cause of morbidity and mortality in hospitalized patients. CLABSI surveillance establishes rates for internal and external comparison, identifies risk factors, and allows assessment of interventions. Objectives: To determine the frequency of CLABSIs among adult patients admitted to intensive care units (ICUs) in CNISP hospitals and evaluate trends over time. Methods: CNISP is a collaborative effort of the Canadian Hospital Epidemiology Committee, the Association of Medical Microbiologists and Infectious Disease Canada and the Public Health Agency of Canada. Since 1995, CNISP has conducted hospital-based sentinel surveillance of healthcare-associated infections. Overall, 55 CNISP hospitals participated in ≥1 year of CLABSI surveillance. Adult ICUs are categorized as mixed ICUs or cardiovascular (CV) surgery ICUs. Data were collected using standardized definitions and collection forms. Line-day denominators for each participating ICU were collected. Negative-binomial regression was used to test for linear trends, with robust standard errors to account for clustering by hospital. We used the Fisher exact test to compare binary variables. Results: Each year, 28–42 adult ICUs participated in surveillance (27–37 mixed, 6–8 CV surgery). In both mixed ICUs and CV-ICUs, rates remained relatively stable between 2011 and 2018 (Fig. 1). In mixed ICUs, CLABSI rates were 1.0 per 1,000 line days in 2011, and 1.0 per 1,000 line days in 2018 (test for linear trend, P = .66). In CV-ICUs, CLABSI rates were 1.1 per 1,000 line days in 2011 and 0.8 per 1,000 line days in 2018 (P = .19). Case age and gender distributions were consistent across the surveillance period. The 30-day all-cause mortality rate was 29% in 2011 and in 2018 (annual range, 29%–35%). Between 2011 and 2018, the percentage of isolated microorganisms that were coagulase-negative staphylococci (CONS) decreased from 31% to 18% (P = .004). The percentage of other gram-positive organisms increased from 32% to 37% (P = .34); Bacillus increased from 0% to 4% of isolates and methicillin-susceptible Staphylococcus aureus from 2% to 6%). The gram-negative organisms increased from 21% to 27% (P = .19). Yeast represented 16% in 2011 and 18% in 2018; however, the percentage of yeast that were Candida albicans decreased over time (58% of yeast in 2011 and 30% in 2018; P = .04). Between 2011 and 2018, the most commonly identified species of microorganism in each year were CONS (18% in 2018) and Enterococcus spp (18% in 2018). Conclusions: Ongoing CLABSI surveillance has shown stable rates of CLABSI in adult ICUs from 2011 to 2018. The causative microorganisms have changed, with CONS decreasing from 31% to 18%.
Disclosures: Allison McGeer reports funds to her for studies, for which she is the principal investigator, from Pfizer and Merck, as well as consulting fees from Sanofi-Pasteur, Sunovion, GSK, Pfizer, and Cidara.
Reply to Weber, von Cube, Sommer, Wolkewitz: Necessity of a Competing Risk Approach in Risk Factor Analysis of Central-Line–Associated Bloodstream Infection
Stefan Kuhle, Jillian H. Carter, Susan Kirkland, Joanne M. Langley, Bryan Maguire, Bruce Smith
Journal: Infection Control & Hospital Epidemiology / Volume 38 / Issue 4 / April 2017
Published online by Cambridge University Press: 31 January 2017, p. 511
Print publication: April 2017
Risk Factors for Central Venous Catheter–Associated Bloodstream Infection in Pediatric Patients: A Cohort Study
Jillian Hansen Carter, Joanne Marie Langley, Stefan Kuhle, Susan Kirkland
Journal: Infection Control & Hospital Epidemiology / Volume 37 / Issue 8 / August 2016
Published online by Cambridge University Press: 03 May 2016, pp. 939-945
Print publication: August 2016
To examine the incidence of central-line–associated bloodstream infection (CLABSI) over time and to determine risk factors for CLABSI in hospitalized children.
Prospective cohort study.
Pediatric tertiary care referral center in Halifax, Nova Scotia, serving a population of 2.3 million.
Patients ages 0–18 years with central venous catheters (CVCs) inserted at this facility between 1995 and 2013.
Participants were followed from CVC insertion to CLABSI event or until CVC removal. Data were prospectively collected by clinicians, infection prevention and control staff, and nursing staff for the purposes of patient care, surveillance, and quality improvement. Cox proportional hazards regression was used to identify risk factors for CLABSI.
Among 5,648 patients, 385 developed CLABSI (0.74 CLABSI per 1,000 line days; or 3.87 per 1,000 in-hospital line days). Most infections occurred within 60 days of insertion. CLABSI rates decreased from 4.87 per 1,000 in-hospital line days in 1995 to 0.78 per 1,000 in-hospital line days in 2013, corresponding to an 84% reduction. A temporal association of CLABSI reduction with a hand hygiene promotion campaign was identified. CVC type, number of lumens, dressing type, insertion vein, and being in the critical care unit were statistically significantly associated with CLABSI.
Hospital-wide surveillance over an 18-year period identified children at highest risk for CLABSI and decreasing risk over time; this decrease was temporally associated with a hand hygiene campaign.
Infect Control Hosp Epidemiol 2016;37:939–945
Study of Cerebrospinal Fluid Shunt–Associated Infections in the First Year Following Placement, by the Canadian Nosocomial Infection Surveillance Program
Joanne M. Langley, Denise Gravel, Dorothy Moore, Anne Matlow, Joanne Embree, Donna MacKinnon-Cameron, John Conly, Canadian Nosocomial Infection Surveillance Program
Journal: Infection Control & Hospital Epidemiology / Volume 30 / Issue 3 / March 2009
Print publication: March 2009
In a national surveillance system study, the infection rate following cerebrospinal fluid shunt surgery was 4.1% (95% confidence interval, 3.36%-4.92%). Cases of infection were more common in children than in adults (4.85% vs 3.24%; P = .04) and occurred sooner after surgery in children than in adults. A wide variation in compliance with antimicrobial prophylaxis was observed between 21 participating medical centers.
Fetal exposure to a maternal low-protein diet during mid-gestation results in muscle-specific effects on fibre type composition in young rats
Joanne E. Mallinson, Dean V. Sculley, Jim Craigon, Richard Plant, Simon C. Langley-Evans, John M. Brameld
Journal: British Journal of Nutrition / Volume 98 / Issue 2 / August 2007
Published online by Cambridge University Press: 01 August 2007, pp. 292-299
This study assessed the impact of reduced dietary protein during specific periods of fetal life upon muscle fibre development in young rats. Pregnant rats were fed a control or low-protein (LP) diet at early (days 0–7 gestation, LPEarly), mid (days 8–14, LPMid), late (days 15–22, LPLate) or throughout gestation (days 0–22, LPAll). The muscle fibre number and composition in soleus and gastrocnemius muscles of the offspring were studied at 4 weeks of age. In the soleus muscle, both the total number and density of fast fibres were reduced in LPMid females (P = 0·004 for both, Diet × Sex × Fibre type interactions), while both the total number and density of glycolytic (non-oxidative) fibres were reduced in LPEarly, LPMid and LPLate (but not LPAll) offspring compared with controls (P < 0·001 for both, Diet × Fibre type interaction). In the gastrocnemius muscle, only the density of oxidative fibres was reduced in LPMid compared with control offspring (P = 0·019, Diet × Fibre type interaction), with the density of slow fibres being increased in LPAll males compared with control (P = 0·024, Diet × Sex × Fibre type interaction). There were little or no effects of maternal diet on fibre type diameters in the two muscles. In conclusion, a maternal low-protein diet mainly during mid-pregnancy reduced muscle fibre number and density in 4-week-old rats, but there were muscle-specific differences in the fibre types affected.
The Role of Clostridium difficile and Viruses as Causes of Nosocomial Diarrhea in Children
Joanne M. Langley, John C. LeBlanc, Martha Hanakowski, Olga Goloubeva
Journal: Infection Control & Hospital Epidemiology / Volume 23 / Issue 11 / November 2002
Print publication: November 2002
We report surveillance of nosocomial diarrhea in children at our institution during the past decade and note different epidemiology of diarrhea due to viruses and Clostridium difficile.
A prospective cohort study.
A university-affiliated pediatric hospital with 180 beds serving an urban area and providing referral care for the Maritime Provinces of Canada.
Children younger than 18 years.
Surveillance was conducted from 1991 to 1999 using personal contact with personnel and review of microbiology and medical records. Nosocomial diarrhea was defined as loose stools occurring more than 48 hours after admission, with at least two loose stools in 12 hours and no likely non-infectious cause.
Nosocomial diarrhea was the third most common nosocomial infection (217 of 1,466; 15%), after bloodstream and respiratory infections, with from 0.5 to 1 episode per 1,000 patient-days. Of 217 nosocomial diarrhea episodes, 122 (56%) had identified pathogens: C. difficile (39 of 122; 32%), rotavirus (38 of 122; 31%), adenovirus (36 of 122; 30%), and other viral (9 of 122; 7%). The median age was 1.3 years (range, 11 days to 17.9 years), 0.80 year for children with viral diarrhea, 3.9 years for children with C. difficile, and 1.5 years for children with diarrhea without a causative organism identified (P< .0001). Most children with nosocomial diarrhea were incontinent (diapered) at the time of their first episode (138 of 185; 75%), but preexisting incontinence was more common in those with viral diarrhea (93%) compared with those with no organism identified (71%) or those with C. difficile-associated diarrhea (CDAD) (49%) (P< .0001).
C. difficile is the single most common cause of nosocomial diarrhea in our tertiary-care center, although all viral pathogens account for 69% of cases. Diapered status appears to be a risk factor for CDAD in children, and CDAD occurs more often in older children than viral nosocomial diarrhea. Further characterization of risk factors for, and morbidity associated with, nosocomial CDAD in children is warranted.

redpajama_set_name: RedPajamaCommonCrawl


text:
Dagogo Relaunched
By: Constantine Soo | January 2009
Dagogo was launched during Thanksgiving 2003, and we have grown steadily since then. To our readers and the companies that support us, we owe you our thanks.
In its almost 6 years of presence on the web, Dagogo has had progressive enhancements to its features and layout. Although the progression in enhancement had complimented the magazine's growth steadily, I thought it was time for Dagogo to have a complete overhaul.
On July 3rd, the new Dagogo was launched on time for the July 4th Celebration. The redesign of Dagogo is so fundamental and extensive that previously adopted formatting practices, including that of manual URL authoring, have become obsolete. Consequently, except for the landing Front Cover page of www.dagogo.com, all Dagogo URLs must be renamed to fit into the new, advanced architecture so brilliantly (and expensively) executed by the web design team. To the readers who have bookmarked Dagogo's Reviews and to the companies who have linked their websites to Dagogo's Reviews, we thank you for your support, but I would also like to first extend my sincerest apologies for the temporary inconvenience and to assure Dagogo's readers, as well as all the companies that so generously porvided us with review samples of a new Dagogo experience that is several times more rewarding than the old one, that the initial trouble of re-bookmarking your favorite Dagogo articles and relinking your website to the Dagogo Reviews is well worth it. Good news is, as of July 8th, we have completed the reformatting of all 2009 articles. The reintegration of all Dagogo Reviews is ongoing.
The new Dagogo now gives you the flexibility of signing up for an RSS Feed, which notifies you automatically of new article postings. In addition, while you are at the inside pages, you are now able to share your favorite Dagogo Review with your friends either via email, MySpace, Facebook, Twitter and more. But this is only the beginning. We now offer all companies in the high-end audio industry the flexibility to post their latest press releases onto Dagogo. While all postings are still subject to editorial approval to ensure the readers of a worthy and pleasant reading experience, we aim at making Dagogo's readers the most informed. If you will give us a chance, we will work hard to make your stay at Dagogo fun.
Dagogo also believes that the high-end audio industry cannot prosper without brick-and-mortar retailers. One of the fundamental reasons the high-end audio industry was able to grow in the 80s and 90s is the proliferation of retailers. Now, imagine a world where you can no longer look up a local retailer and audition electronics and speakers in person. The continuing demise of the dealership network diminishes the industry's ability to recruit new customers of the upcoming generations; the very witnessing and living in today's reality is already a heartbreaking and frightening one. Although the industry may eventually go through a cycle of rebirth, the dark road that we all will have to traverse before the renaissance is much too daunting to even fathom. We must try to prevent it, and now is the time to raise awareness of the invaluable importance of dealership networks and the key role they play in preserving the health of an industry.
In light of this, Dagogo would like to extend an invitation to all dealers to send a picture or two of your listening room to the editor (editor@dagogo.com). Selected pictures will be used as Dagogo's Front Cover in future Issues. The image must be at least 300kb in size and 970 pixels wide and 600 pixels tall. Set your camera to at least 1MB when taking the shot, and make sure the shot is of the entire listening room and not a closeup of a rack. Consult a female staff on what fixtures to include and exclude, a woman's touch usually helps. If it's your wife, just tell her beforehand that the rearrangement won't be permanent but just for the picture. For the very gracious dealers who supported Dagogo's Front Cover campaign since earlier this year, we have archived the past Front Covers for everyone's viewing pleasure.
Once again, we at Dagogo thank everyone for your continuous support, and we promise to make Dagogo better for you.


Obsidian messenger is going to secure metadata of users by using blockchain. The user will not have to use email or any other authentication information in order to use the messenger. The metadata will be randomly distributed throughout a ledger and thus will not be available for gathering in one single point, from which it could then be hacked. They are also planning on introducing their own token as a method of payment inside the Obsidian Messenger. This startup is still under development, but other messengers will follow the scheme and secure their user's data in a similar way.
Anabel is a 26-year old editor and writer from Harlow with a deep interest in cybersecurity and a belief that a private life is a human right. Though she is not a professional writer, she enjoys writing articles about subjects she is passionate about. Anabel has a master's degree in Literature and works as a copyreader and news writer in Longman.


text:
Q: Is it possible to create EM radiation moving in an opposite direction to that from an accelerated charge? The Lienard-Wiechert retarded solution to Maxwell's equations has the radiation fields diverging and propagating away from an accelerating charge; the advanced solution has radiation fields converging onto the charge.
Obviously an accelerating charge can generate the retarded EM radiation, but does there exist a charge distribution able to generate the advanced EM radiation converging to a point?

A: In macroscopic EM theory, such phenomenon is extremely unlikely, as the reports of its observations are few and fringe. Theoretically it means distant EM field in every direction now is correlated with the localized charge distribution motion in the future, which is hard to accept for  its acausal description of EM field (EM field could no longer be thought of as created by the charge distribution).
The EM field could manifest a component of advanced character if such "acausal" correlation was caused by experimenter, for example by putting a spherical reflector around the charge distribution - then there would be an incoming wave collapsing on the charge distribution - but it would be only a part of the total EM field, not all of it.
In microscopic EM theory, we do not know - there are attempts to explain macroscopic EM phenomena as a result of microscopic fields that contain but aren't equal to advanced fields (action at a distance theories of Tetrode, Fokker, Frenkel, Feynamn-Wheeler). But these attempts to use advanced fields to advance our understanding of EM phenomena had limited success.

A: The advanced solution has radiation fields diverging and propagating away from an accelerating charge too. The problem is that human beings are experiencing outgoing advanced waves (traveling backwards in time) as incoming waves (traveling forward in time) and converging to a point, as explained in this paper: https://www.researchgate.net/publication/320163131_The_hidden_arrow_of_electromagnetic_radiation_unmasking_advanced_waves

redpajama_set_name: RedPajamaStackExchange


Wholesale Oil Paintings From China, Wholesale Reproduction Of Old Master Artwork And Picture Frames.
Wholesale Oil Paintings From China, Wholesale Art Reproduction Of Old Master Artwork, Wholesale Picture Frames.
We want to thank you for inquiring about our wholesale oil paintings, if you are an Art Retailer, Art Dealer, Art Gallery, Wholesaler, Distributors, Interior Design or Furniture Company, welcome to order the oil paintings with wholesale price, To place an order please contact us with your request.
Minimum order is $1000 or 100 pieces paintings, 5 pieces for each design, There is 5% discount for order over $1000 and 10% discount for order over $2000. more order more discount, All discount applies to painting order only.
Compare to our quality artwork in high rank material, our price is unbelievable competitive and affordable, the precise price base on the specified design and size.
Feel free to order online in Artist, Subject, Sample, Stock, Special price and Picture Frame section, or send your custom image for order, we will paint whatever you want, the artwork only takes about 7 days depends on the quantity and size you order.
All paintings and frames will be shipped by Ocean Shipping or Air Shipping.


text:
Strong growth in new B2B customer orders has driven positive cashflow results for CV Check.
Screening and verification company CV Check (ASX: CV1) has recorded the best start to a financial year in its entire history, after achieving yet another cash flow positive quarter – its third in a row.
According to chief executive officer Rob Sherwood, the company's strongest start to a financial year now leaves it "primed for rapid growth in the 2020 financial year".
CV Check says it has secured further business-to-business (B2B) customers which were largely responsible for its "impressive" quarter.
However, shareholders will have to wait a few weeks before seeing specific details relating to performance. Further details of its record-breaking year are expected to be published in a comprehensive update as part of a quarterly cash flow report at the end of July.
In today's update, CV Check noted it recorded positive cash generation of $26,000 from normal operating and investing activities for the past quarter.
The result represents a $704,000 improvement on a quarter-on-quarter basis and brings its total cash balance to $3.1 million, a 105% improvement.
White label boost
More specifically, CV Check attributed its best quarter to a new white label feature that is helping to propel its customer base growth.
During the past quarter, CV Check released phase one of its white label screening and verification solution and found immediate success by securing Visy Industries as the white label's foundation large enterprise customer.
Additionally, an as yet unnamed university and a construction company are currently implementing their "tailored" white label solutions, first conceived and during the past six months.
CV Check provides check products to employers, industry associations and individuals via the CV Check brand on its proprietary online platform.
The company has been operating for more than 10 years and has developed a robust online platform providing a comprehensive range of checks across the globe.
Charity market
Earlier this week, CV Check announced that the Public Fundraising Regulatory Association (PFRA) adopted the company's product as part of its regulatory function in the charities and not-for-profit industry sector.
The industry already comprises more than 50,000 registered charities across Australia with hundreds more registering every month which means CV Check will have a growing addressable audience.
The PFRA is responsible for industry self-regulation and its members comprise over 85 major enterprises operating globally.
Since commencement in early June, this approach has already resulted in accounts being set up by over 15% of the members. The company has declared that "orders have been received and revenue is already being booked".
The full scale of the opportunity is being assessed but for those enterprises that have already on-boarded the annual recurring revenue per account is expected to range between $12,500 and $25,000.
"CV Check is delighted to have won Visy Industries with the decisive factor being our phase one white label solution. Visy Industries is already ordering whilst our other notable wins are in the account set up and user onboarding phase," Mr Sherwood..
"The result is particularly noteworthy as it comes after absorbing the cost of doubling our salespeople and added marketing spend in the quarter."
"The solid financial performance was driven by our rapidly expanding B2B activities which are delivering a steady increase in predictable annualised recurring revenue. Continued investment in CV Check's proprietary technology platform underpins the company's major market advantage," said Mr Sherwood.
This morning's financial performance helped CV Check's shares to add almost 5% up to $0.225.


Samantha Akkineni is undoubtedly one of the most talented and versatile actresses in Telugu Film Industry. From her ability to emote on-screen to her dancing grooves, Nagarjuna's daughter-in-law has gone on to carve a niche for herself and has managed to find fans in those who have not watched her movies too. Once again, Samantha Akkineni is winning the hearts of her fans because of her hot and spicy avatar th her latest photoshoot.
Check out Gorgeous Samantha Hot Black Dress Photoshoot, Latest Stills of Stunning Beauty Samantha RuthPrabhu.


text:
Milarepa Cave or Milerepa Cave is a cave associated with Milarepa in Nepal on the Annapurna Circuit at approximately  just outside Manang. It is credited to have been the residence of the famous Tibetan Buddhism siddha Milarepa during his stay in 11th century in what is now modern-day northern Nepal. This site also includes a holy spring and a gompa. The cave is located beyond the gompa, with locals praying from the edge of a glacial moraine in direct line of sight of the cave as its approach is on a steep scree slope.

A bow can be seen hanging from the nearby cliff. The bow is purportedly from the local hunter named Kera Gompa Dorjee, who tried to kill Milarepa over an argument about slaying animals. Milarepa taught the hunter causation and compassion through a Buddhist song, which became the classic hymn known as Milarepa's Song to the Hunter. According to local folklore, this is the site of this famous tale.

References

See also
Milarepa's Cave, Nyalam

Buddhist monasteries in Nepal
Buddhist temples in Nepal

Tibetan hermitages
Gelug monasteries
Buddhist caves
Buildings and structures in Manang District, Nepal

redpajama_set_name: RedPajamaWikipedia


text:
Bulgarian bg Chinese zh Czech cs Danish da Dutch; Flemish nl French fr Georgian ka German de Greek el Hungarian hu Indonesian id Italian it Korean ko
Popular Now Playing Top Rated Upcoming
Popular Top Rated On TV Airing Today
Action Adventure Animation Comedy Crime Documentary Drama Family Fantasy History
Horror Music Mystery Romance Science Fiction TV Movie Thriller War Western
Steven Andrew Soderbergh was born on January 14, 1963 in Atlanta, Georgia, USA, the second of six children of Mary Ann (Bernard) and Peter Soderbergh. His father was of Swedish and Irish descent, and his mother was of Italian ancestry. While he was still at a very young age, his family moved to Baton Rouge, Louisiana, where his father was a professor and the dean of the College of Education at Louisiana State University. While still in high school, around the age of 15, Soderbergh enrolled in the university's film animation class and began making short 16-millimeter films with second-hand equipment, one of which was the short film "Janitor". After graduating high school, he went to Hollywood, where he worked as a freelance editor. His time there was brief and, shortly after, he returned home and continued making short films and writing scripts. His first major break was in 1986 when the rock group Yes assigned him to shoot a full-length concert film for the band, which eventually earned him a Grammy nomination for the video, Yes: 9012 Live (1985). Following this achievement, Soderbergh filmed Winston (1987), the short-subject film that he would later expand into Sex, Lies, and Videotape (1989), a film that earned him the Cannes Film Festival's Palme d'Or Award, the Independent Spirit Award for Best Director, and an Oscar nomination for Best Original Screenplay. Over the next six years, he was married to actress Betsy Brantley and had a daughter named Sarah Soderbergh, who was born in 1990. Also during this time, he made such films as Kafka (1991), King of the Hill (1993), The Underneath (1995) and Gray's Anatomy (1996), which many believed to be disappointments. In 1998, Soderbergh made Out of Sight (1998), his most critically and commercially successful film since Sex, Lies, and Videotape (1989). Then, in 2000, Soderbergh directed two major motion pictures that are now his most successful films to date: Erin Brockovich (2000) and Traffic (2000). These films were both nominated for Best Picture Oscars at the 2001 Academy Awards and gave him the first twin director Oscar nomination in almost 60 years and the first ever win. He won the Oscar for Best Director for Traffic (2000) at the 2001 Oscars.
Known For: Directing
Place of Birth: Atlanta, Georgia, USA
Also Known As: Peter Andrews, Mary Ann Bernard, Sam Lowry, Стивен Содерберг, 史蒂文·索德伯格, スティーブン・ソダーバーグ, 스티븐 소더버그, ستيفن سودربرغ, Стівен Содерберґ
Movies List of Steven Soderbergh
Schizopolis (1997)
Stanley Kubrick in Focus (2012)
CHE and the Digital Cinema Revolution (2009)
Marvin Hamlisch: What He Did For Love (2013)
The Legend of the Palme d'Or (2015)
Independent's Day (1998)
Porn: Business of Pleasure (2009)
X-Rated 2: The Greatest Adult Stars of All-Time (2016)
Five Directors on THE BATTLE OF ALGIERS (2004)
Gina Carano in Training (2012)
The Men of Haywire (2012)
The Last Time I Saw Michael Gregg (2011)
I Ain't Scared of You: A Tribute to Bernie Mac (2012)
Alan Pakula: Going for Truth (2019)
Waking Life (2001)
Full Frontal (2002)


Home > 860H075 Timing belt. 860H-075-G Timing belt.
860H075 Industrial Timing belt. 860H-075 HTD Timing belt.
860H075 Timing belt. 860H-075-G Timing belt.
860H075 Industrial Grade HTD Timing Belt. 86" Length. 172 teeth. 3/4" (0.75") wide. Neoprene (black rubber) replacement "860-H Series" industry standard Timing Belt. Popular replacement belt for industrial printing equipment and power tools such as CNC, woodworking tools & lathes, pumps, and robotic equipment. *SPECIAL PRICE WHILE SUPPLIES LAST!
Category: Standard Synchronous, Timing Belt - H, 0.75 x 86in PL, T172.
Toothed Gear Belts marked "860H " at 3/4" Width.
Imported Richeng/Great Wall 860H -075.


text:
Q: Protractor not passing my tests without the done() method I am actually finishing the unit tests of my Angular app. I am currently working on E2E tests using Protractor and Jasmine. Unfortunately, I have the following problem:
I did loads of research online  such as http://ramonvictor.github.io/protractor/slides/#/1 and I clearly never see the use of the "done" callback to launch tests.
This first test goes on the createUser page and makes sure that the user tab attribute is set to active. It passes ONLY if I use the done method, which I should not use.

'use strict';

var UserCreate = require('./page-objects/userCreate.pageObjects');

describe('on init', function () {

    beforeEach(function() {
       var rootUrl = browser.baseUrl + '/#/users/create';
       browser.driver.get(rootUrl);
    });

    it('should set the user tab active', function(done) { // DONE callback
        UserCreate.tabs.getAttribute('class').then(function(value) {
            expect(value).toEqual('active');
            done(); // calling callback
        });
     });
 });

If I repeat the same test without using done(), the test passes even if this time, I want it to fail.

'use strict';

var UserCreate = require('./page-objects/userCreate.pageObjects');

describe('on init', function () {

    beforeEach(function() {
       var rootUrl = browser.baseUrl + '/#/users/create';
       browser.driver.get(rootUrl);
    });

    it('should set the user tab active', function() {
        UserCreate.tabs.getAttribute('class').then(function(value) {
            expect(value).toEqual('activeWRONG');
        });
     });
 });

It only fails if I use the done callback.
Here is my config file:

 /* conf.js */
'    use strict';

exports.config = {
rootElement: '#myApp',
directConnect: true,
seleniumAddress: 'http://localhost:4444/wd/hub',
capabilities: {
    browserName: 'chrome',
    shardTestFiles: true,
    maxInstances: 1
},
framework: 'jasmine',
// specs: ['./*.spec.js'],
baseUrl: 'http://localhost:9001',
defaultTimeoutInterval: 0000,
jasmineNodeOpts: {
    showColors: true,
},
suites: {
    wip:        './userCreate.spec.js',
    all:        './*spec.js'
},
onPrepare: function() {
    browser.driver.get('http://localhost:9001/#/');
    element(by.id('ld-link-login')).click();
    browser.sleep(500);

    element(by.model('username')).sendKeys('test');
    element(by.model('password')).sendKeys('test');
    element(by.id('nv-login-submit')).click();

    return browser.driver.wait(function() {
        return browser.driver.getCurrentUrl().then(function(url) {
            return /dashboard/.test(url);
        });
    }, 10000);
}
};

I am having asynchronous problems in deeper tests with the use of done everywhere, so I want to fix this before continuing my tests.
Thank you for your help.
Edit:
Protractor version:  ./node_modules/.bin/protractor --version gives Version 3.2.2
userCreate.pageObjects :

'use strict';

 module.exports = {
    tabs: element(by.id('cc-tab-user'))
  };

A: That's the expected behaviour. If you don't ask for the done() function, jasmine will consider your test as synchronous and finish without waiting for the promise to be resolved.
When you ask for it, your test became asynchronous, and will fail if done() hasn't been called before the timeout ( 5 seconds by default)
See: http://jasmine.github.io/2.0/introduction.html#section-Asynchronous_Support for more info.

A: You have a problem in the way you are defining the Page Object leading into the problem with the promise resolution order. Follow the style guide and change it to:
var UserCreatePage = function() {
  this.tabs = element(by.id('cc-tab-user'));
};

module.exports = UserCreatePage;

Usage:
'use strict';

var UserCreatePage = require('./page-objects/userCreate.pageObjects');

describe('on init', function () {
    var userCreatePage;

    beforeEach(function() {
       var rootUrl = browser.baseUrl + '/#/users/create';
       browser.driver.get(rootUrl);

       userCreatePage = new UserCreatePage();
    });

    it('should set the user tab active', function() {
        userCreatePage.tabs.getAttribute('class').then(function(value) {
            expect(value).toEqual('activeWRONG');
        });
     });
 });

A: This behavior can happen if your test creates a parallel TaskQueue in your test's Control Flow. For what done() is for and how to use it ( protractor, jasmine) I wrote a few examples of tests giving inconsistent results because of this.
To figure out if this is your problem, you can print out the control flow at various points in your test:
console.log(protractor.promise.controlFlow().getSchedule(false));

A: Your issue is, that you use the then() to pass value towards your expect-statement.
then() creates a new async-task, which is dropped as subtask. As result of this, your it first finishes with result = success and then your expect-statement gets executed.
It's documented in the Promise/ControlFlow documentation of Selenium.
As expect() already unwraps/resolves a promise, there is no need for then() in your case.
With your done it works, because you take control of the execution and prevent it to continue/finish before your then() is  finished.
Try this:
'use strict';

var UserCreate = require('./page-objects/userCreate.pageObjects');

describe('on init', function () {

    beforeEach(function() {
       var rootUrl = browser.baseUrl + '/#/users/create';
       browser.driver.get(rootUrl);
    });

    it('should set the user tab active', function() {
        expect(UserCreate.tabs.getAttribute('class')).toEqual('activeWRONG');
    });
});

A: It is because of the control flow which is not running properly in your code . The control flow is based on the concept of tasks and task queues. Tasks are functions that define the basic unit of work for the control flow to execute. Each task is scheduled via ControlFlow#execute(), which will return a ManagedPromise that will be resolved with the task's result.
The following should work.
let UserCreate = require('./pageobject.page.js');
describe('should navigate to url', function () {
    beforeEach(function() {
      url = `${browser.baseUrl}/#/users/create`;
      browser.driver.get(url);
    });
    it('should set the user tab active', function() {
   expect(UserCreate.tabs.getAttribute('class')).toEqual('activeWRONG');
    });
});


I love the lighting from the sun in this picture.
Beautiful photo! I love the details!
Thanks for sharing this beautiful photograph! I was already following you via GFC and just followed you via Bloglovin so it would be so nice if you followed me via GFC if not already and follow me on Bloglovin so we support each other and keep in touch!
Hi! Wow! Very nice photo!


text:
Here's Willie Nelson è il secondo album in studio dell'artista country statunitense Willie Nelson, pubblicato nel 1963.

Tracce
Tutte le tracce sono di Willie Nelson tranne dove indicato.
Roly Poly (Fred Rose)
Half a Man
Lonely Little Mansion
The Last Letter (Rex Griffin)
Second Fiddle (Roger Miller)
Take My Word
Right or Wrong (Haven Gillespie, Arthur Sizemore, Paul Biese)
Feed It a Memory (Hank Cochran, Justin Tubb)
Let Me Talk to You (Danny Dill, Don Davis)
Way You See Me
Things I Might Have Been (Robert B. Sherman, Richard M. Sherman)
Home Motel

Collegamenti esterni


text:
What's on the horizon for bioethics?
Download a PDF
Human reproduction
Whole genome sequencing of embryos and fetuses
Pregnant women and couples can have prenatal screening for several genetic conditions in the first trimester of pregnancy. Embryos can undergo pre-implantation genetic diagnosis during IVF. The number and type of conditions that embryos and fetuses can be screened for is likely to increase, with whole genome sequencing a possibility in future. Will this have real benefits for health, or simply create confusion and worry for parents, and is it ethical to obtain and store this information without the child's consent?
Preconception screening
Couples with a family history can have genetic testing before they conceive to find out if they are carriers for conditions like cystic fibrosis. Testing is likely to become cheaper and more accessible, allowing any couple to test for a wide range of genetic conditions and features relatively cheaply. Should there be limits on what people can test for?
The number of women choosing to freeze their eggs is growing rapidly, and some companies are already offering egg freezing as an employee benefit. This trend is likely to continue, but IVF with frozen eggs has a low success rate. Should we be worried about women feeling coerced into freezing their eggs, and what could be the knock-on social effects of this trend for women?
Genome editing of gametes and embryos
It could become possible to use genome editing to alter the DNA of embryos, sperm or eggs to help a couple have a child without a particular heritable disorder. A Chinese researcher has claimed that gene-edited twin girls have already been born. This is currently illegal in the UK. Before it can be permitted, consideration is needed of the clinical safety of the techniques, and their potential to impact on the welfare of the future person, and on discrimination and division in society.
In vitro derived gametes
Mouse sperm and eggs cells can be created in the lab from other cells in the mouse's body, resulting in fertile offspring. This could become possible for humans in future, offering a new kind of fertility treatment for couples who cannot conceive and overcoming the shortage of eggs for research. It could also increase the risk of children being produced without one of the parent's consent or knowledge, and raises questions about what ethical significance ought to be placed on genetic parenthood.
Womb replacements
Researchers have kept premature lambs alive in artificial wombs for several weeks. This technology might help improve outcomes for premature human babies in future. Looking further ahead, when more or all of pregnancy might one day take place outside the human body, would the use of artificial wombs lead to social changes relating to the nature of motherhood and parenthood?
Time limits on maintaining embryos in culture
UK law, set in 1990, states that human embryos cannot be kept or used for research for longer than 14 days. Recent research showed that it might now be possible to sustain embryos for longer, raising questions about whether the time limit should be extended. New entities, such as SHEEFS (synthetic human entities with embryo-like features), add to questions about the continuing relevance of the law.
Shaping human beings
Synthesizing entire human genomes
Researchers have synthesized entire bacteria in the lab, and the possibility of creating human cells from scratch is now being explored. The cells could be engineered to resist viruses, radiation, freezing, aging and cancer, and would be a valuable resource for research. Such a development would raise significant ethical and philosophical questions about the nature of life, parenthood, and scientific hubris.
Cognitive enhancement
New drugs and techniques, such as transcranial magnetic stimulation, that might enhance cognitive function are being explored in a range of contexts, including education, military, employment and sport. Would this give some people an unfair advantage, and is this cheating or 'playing God'?
Moral enhancement
Could and should we intervene in the biological bases of human motivation, using drugs, genetic selection or neurotechnologies, to enhance our sense of morality? Some philosophers suggest that moral enhancement is necessary for tackling the major challenges facing society.
This emerging area of research uses implanted devices to read and modulate the electrical activity within the body's nervous system for the purposes of diagnosis or treatment of neurological disorders and chronic conditions. There is also interest in using the technology for improving the efficiency of military personnel. The techniques could be used to inflict pain without visible harm to an individual and raise issues relating to privacy, identity and autonomy.
'Biohackers apply the hacker ethic to change or enhance the human body, using devices and implants, gene editing, drugs and pathogens. The emphasis is on self-experimentation, creation, and modification of existing technology. Should biohackers be prevented from harming themselves, and do they pose a threat to national security?
Sporting performance can be improved through biomechanics, genetics, materials science, nutrition, pharmaceuticals, physiology, psychology, and surgery. Technology is advancing all the time. Where should the lines be drawn and where do responsibilities lie for the potential harmful effects and other consequences?
Beginning and end of life
Debate about UK abortion law is likely to continue well into the future. This is a polarised issue that has implications for areas of medicine such as prenatal screening. Some are campaigning to decriminalise abortion across the UK, but others are seeking to reduce the upper time limit for abortions in response to changes in the thresholds of fetal viability.
Whole genome sequencing of newborn babies
In future, the parents of all newborn babies might be offered whole genome sequencing to identify their baby's risk of developing disease and to create a genetic data resource for life. This is likely to be available in the near future to parents through commercial genetic testing companies. Will this have real benefits for health, or simply create confusion and worry for parents, and is it ethical to obtain and store this information without the child's consent?
Decision making in paediatric care
There have been several recent high-profile cases of healthcare teams and parents disagreeing about the care of critically ill children in the UK. Wider changes in society, such as increases in social media use and medical tourism, and advances in medicine might be contributing to the way in which disagreements develop. Are there ways in which disagreements such as these can be avoided, or resolved more quickly?
Treatments for biological ageing
Much effort is going into finding treatments that could delay biological ageing, thereby reducing the risk of age-related diseases and conditions. Clinical trials of drugs that target ageing are already underway. If effective interventions became available, these could have implications for health and lifespan, the economy, models of care, personal identity, and how people work and live later in life.
Assisted dying
In the UK, assisting or encouraging another person to commit suicide is a criminal offence. There have been several attempts to liberalise the law to align with some European countries and states in the USA, but this has been met with resistance particularly from the medical profession. MPs rejected an Assisted Dying Bill in 2015, but the debate is likely to return to Parliament in future
Cryonic freezing after death
Cryogenic freezing of humans in an attempt to avoid permanent death is commercially available, but the likelihood of ever being revived is low. However, there is little regulatory oversight and, if revival was achieved, it would raise complex questions about the nature of consciousness and identity, and our understanding of the nature of death.
Health and society
Patients, or parents and carers of patients, with limited options might wish to try experimental treatments despite uncertainties about safety and efficacy. Now that patients can easily find out about and crowdfund experimental treatments online, a key challenge will be respecting the interests and autonomy of patients while ensuring they are protected from harm.
Increasing levels of antimicrobial resistance is a major global issue affecting health, agriculture, and the economy. There are serious implications for future generations. Interventions that aim to limit antimicrobial resistance might affect people unevenly across the world, reduce farming yields and increase food costs, and require the restriction of individual liberty.
Microbiome research
Research is exploring how the human microbiome – i.e. the microorganisms living in the body – can be manipulated for therapeutic benefit. Treatments already in use include faecal transplants and dietary supplements. Microbiome analysis can reveal information about a person's behaviour, and microbiome composition has been known to affect behaviour. Microbiome research and intervention raises questions about privacy and the nature of individual responsibility for health.
Researchers are understanding more and more about epigenetics – changes in gene expression caused by environmental effects, such as diet, stress, smoking, and childhood trauma. These effects might begin in the womb. Epigenetics research could have applications in many areas of policy, such as public health, healthcare and early years intervention. As the science develops, ethical issues relating to intergenerational equity, medicalisation of social problems, and privacy will need attention.
Levels of obesity across the population continue to rise. If they are to be effective, public health interventions of the future might need to go further than public information campaigns, banning fast food advertising, and taxing sugar. What level of state intervention and intrusion in a very personal area of life will be acceptable to people?
Increasing recognition of people with non-traditional gender identities has spurred significant public debate about gender and biology, appropriate medical intervention, and social acceptance. What does this mean for gender restricted roles and activities, such as sporting competitions, and how should interventions to alter sexual characteristics be made available?
Artificial intelligence in healthcare
A wide range of applications of AI are being explored with considerable public and private investment and interest. AI is being used or trialled for detection of disease, management of chronic conditions, delivery of health services, and drug discovery. Ethical issues to consider include difficulties in validating the outputs of AI systems, and the inherent biases in the data used to train AI systems.
Wearable & implantable devices
Current and potential uses of wearable and implantable devices include monitoring health conditions, restoring function, self-tracking, tracking others, identification, sensory extension and communication. People who have implanted devices are sometimes referred to as cyborgs. There are concerns about the tracking or monitoring of individuals and the use of technologies in contexts of imbalanced power relationships, such as employment or education.
Robotics in social care
Care robots could be looking after people in their own homes in future, reducing the burden on social care services. Will robots be reliable enough to look after our most vulnerable citizens safely, and will this lead to a dehumanising of care?
Virtual and augmented reality
VR and AR that emulate or modify perceptions of reality have a number of potential applications in healthcare, eg pain management, psychotherapy, rehabilitation and training. Might this lead to an invasion of privacy if not used in controlled environments, and is there the danger that virtual environments could be too realistic, causing confusion between real and virtual worlds?
Food, farming and the environment
Creating a sustainable food system
The production, transportation, and consumption of sustainable food should take into account effects on the environment, economy, human health, resource efficiency, food quality and safety, nutrition security, and animal welfare. Science and innovation that seeks to increase the sustainability of food in different ways could play an important role. Political, economic and social drivers are likely to have a strong influence on how this area develops.
Genome editing in farmed animals
Genome editing could enable modifications to be made in farmed animals that have previously not been possible. Will it be possible to scale this up to commercially viable levels, what would be the effect on animal welfare, and would it ever be widely accepted by farmers and consumers?
The consumption of meat and animal-derived products is likely to play a prominent role in broader debates about food sustainability, animal welfare, and health. Alternatives to meat include in vitro produced meat and non-animal diets, but will they be acceptable to consumers and economically viable?
De-extinction
Scientists are attempting to 'revive' extinct animals and plants in the lab. For example, genome editing techniques are being used to try to create a hybrid of a woolly mammoth and Asian elephant. If de-extinction become possible, how would species be selected, and would it really have a positive effect on today's ecosystems?
Some practices surrounding the use of biofuels might be harming the environment, for example the burning of wood pellets and deforestation for the supply of pellets and vegetable oil-based fuels. Also, energy policies relating to biofuels in wealthy countries could be having deleterious effects in poorer countries, and there is concern that climate change policies might be over-reliant on biofuel-using technologies.
New ID biometrics
Future identification biometrics might include gait, voice, breath and heart rate recognition, with possible applications in criminal justice, security, healthcare, and commercial fields. Mirroring questions raised by the use of DNA, fingerprints and facial images, will these new biometrics be reliable, and how can they be used in a way that's proportionate to the aim of, e.g. solving crime?
DNA phenotyping
Predicting what someone will look like – their phenotype – from a sample of their DNA is still a fairly inaccurate science, limiting its use in criminal investigations. However, as our understanding of genomics advances, DNA phenotyping is likely to become more precise, but its use is likely to raise concerns about racial bias and invasion of privacy.
Crime prediction
Crime data can be analysed to make predictions about where a crime will take place, allowing police resources to be deployed in advance. It's not yet clear if crime prediction reduces crime, and there are worries that biases in the data could reinforce police prejudices about particular areas and ethnic minorities.
Popular genealogy websites, such as 23andme, are emerging as a new resource for criminal investigators. Although many support the use of any means available to find and prosecute perpetrators of serious crime, some are worried about 'mission creep' and people's data being used for purposes they did not consent to.
Brain scans in the criminal justice system
Brain scans and the resulting neuroscientific data have a range of potential uses in the criminal justice system, for example assessing competency to stand trial, criminal culpability, witness credibility and the risk someone will commit a crime or reoffend, and for lie detection purposes. Even if the technology was proven to be reliable, it would raise a host of ethical issues relating to coercion to undergo scanning, the framing of criminal responsibility, and the possibility of new interventions for criminals being developed.
Dual use technologies
Many technologies can be used for both peaceful and hostile ends. This has always been part of violence between individuals and groups, especially in the context of warfare. Do some new technologies, such as synthetic biology and neurobiology, prompt particular concerns about dual use?
Epigenetic ageing
Tests that analyse a person's 'epigenetic clock' are becoming more accurate at estimating a person's chronological age. There are potential applications in areas where the age of a person is important, for example assessing asylum seekers and refugees, or in disaster situations. This makes this area of research highly political and sensitive, and one where the accuracy of the test will be crucial.
Recent emergencies, such as the Ebola epidemic in Africa, have highlighted the important role of research in the humanitarian response. However, a lack of consensus on what is ethically acceptable during emergencies could be impeding the progress of valuable research, and adding to the risk that research might be carried out in unethical ways.
Participant-led research
Research activities led by patients or volunteers, rather than professional researchers, are increasing in popularity. Research that is controlled by participants challenges the whole basis for traditional research ethics, which focuses on protecting participants from exploitation by researchers. Do traditional research ethics approaches need to adapt and change?
Equity in drug development
There are concerns that the current system of drug development and research does not benefit patients equitably and is unduly influenced by factors other than patient need, such as profit. Areas that might be influenced negatively include the prioritisation and funding of research, data availability, patient safety, and drug licensing.
Use of brain surrogates
'Brain surrogates are being developed to facilitate research on human brain function, including organoids grown from stem cells, preserved human brain slices, and human-animal chimeras. These new techniques might reduce the need for animal research, but raise questions about the nature of suffering, consciousness, humanness and death.
The number of animals used in research continues to increase, largely due to the use of GM mice, and research trends are making research on larger animals more frequent and complex. Is it time to review the way in which research involving animals is being incentivised, carried out, regulated, replaced and shared?


text:
Dedicated Female Coaches Share Their Faith Journeys with Fellowship of Christian Athletes
Deborah Hamilton, Hamilton Strategies, 215.815.7716, 610.584.1096, ext. 102, or Beth Harrison, 610.584.1096, ext. 104, Media@HamiltonStrategies.com
As Women's Basketball Kicks Off Exciting Sweet Sixteen Action This Weekend, Coaches Stress a Desire to Impact Players for a Higher Purpose
KANSAS CITY, Mo—Not to be overshadowed by the men's bracket, the women head to their own exciting NCAA basketball championship action, with 16 teams looking for a sweet win this weekend.
Several of the coaches for the top women's teams have talked to Fellowship of Christian Athletes (FCA, www.fca.org) about their faith, and how they strive to reach their players on a much higher level than the basketball court.
Playing on Saturday is Florida State, who will take on Oregon State, and UCLA, facing UConn. Both Sue Semrau, head coach of Florida State, and Cori Close, who leads the UCLA Bruins, have ties to FCA and are active in sharing their love of Christ with all they meet through the game of basketball.
Sue Semrau | Florida State
A Washington native, Semrau played college basketball at the University of Puget Sound and then UC San Diego. After graduation, she worked in public relations work for professional soccer franchises before landing her first coaching job—or jobs—leading the women's basketball and soccer programs at Division III Occidental College in Los Angeles.
"I didn't think I would ever be a coach," Semrau said. "But once I started, I just really fell in love with the game even more, and it brought about the merging of basketball and my faith."
A lifelong believer in God, it was through a volunteer stint at an FCA Camp that Semrau began to understand the significance of a relationship with Christ. After hearing the testimony of fellow basketball coach Debbie Haliday, Semrau made an on-the-spot decision to begin a new walk with Christ. She began attending a vibrant local church and delved deep into the gift she had been given.
"It wasn't a decision about Jesus," she said. "The Bible says that even Satan believes and shudders when it comes to Jesus. I always believed in Jesus, but so what? So does the devil. It's become less about believing in Jesus and all about truly accepting the gift of salvation I was being offered and what I would do with it.
"It's like a basketball pass," she continued. "You can choose to receive a pass, or you can do nothing and just let it go out of bounds. But once you receive the pass, the real question becomes what you'll do with it. I realized it was time for me to create scoring opportunities."
Semrau's career continued, and at an FCA Camp she met FCA Hall of Champions inductee Jane Albright, who later invited Semrau to her coaching staff at Northern Illinois. Three seasons later, Albright moved to a coaching position at the University of Wisconsin and took Semrau with her as an assistant coach and recruiting coordinator. At that same FCA Camp in 1997, Semrau met folks from Florida State who wanted to interview her for an open head women's basketball coaching job. The Seminoles routinely found themselves at the bottom of the ACC standings during that era and hadn't had a winning record in 10 seasons.
"I had no desire to go to Florida State," Semrau recalled.
But thanks to her renewed relationship with God, she was able to hear His call as clearly as the one she received from FSU administrators. Semrau felt Him telling her to take the next step and go where He was leading.
"I really felt like God was asking me if I feared Him or the world more," she said. "The world said the head coaching position at Florida State was not a good job and that the Seminoles would never be good at basketball. It was a football school. The world also said that you don't take your first Division I head coaching job in the ACC."
But with some fear and trembling, Semrau agreed to head to Tallahassee to take over a team that hadn't reached double figures in wins in four seasons. From day one, she steadily built the Seminoles' program and continued to pour into the FCA community, serving as a coach and speaker at various FCA Camps and clinics throughout the country.
Fast-forward 20 years, and Semrau's Seminoles are perennial powerhouse contenders. Did she ever think she would spend two decades at Florida State? Certainly not. But now she knows the God brings all things together for her good.
"I just don't pay a lot of attention to the future, because, if I could have planned my life in advance, this would not be what I planned," she said. "It's been incredible. It's like an adventure. What's God going to do next? What does He want me to do next? I certainly never guessed I'd be at Florida State for 16 years, so whatever He wants me to do and wherever He wants me to go, I'm open to it."
Read Semrau's FCA stories here and here.
Cori Close | UCLA
Named the women's basketball head coach at UCLA in 2011, Cori Close told FCA she knew UCLA was a great fit for her from the start.
"I've always prayed that God would prepare me to accept the right position when it came along, and this was it," she said. "It's not a job; it's a lifestyle, and I'm getting to share it with friends and family who have invested so much in me. Even in the midst of the chaos and the hard transitioning years ahead, I'm very peaceful because I believe it is the place God has for me."
And during those chaotic times of her job, Close says she focuses on phrase, "give us this day, our daily bread," from the Lord's Prayer.
"Each day can be overwhelming, and there are so many things that I don't get done on my to-do list," Close added. "I'm literally just asking God to give me what I need for that day. When I pray that verse fervently, live it out and let it sink into my heart, I feel closer to Jesus, and that's where I need to stay."
Close also told FCA that one of her coaching goals is to ensure that all she encounters feel valued and loved, whether they share her faith or not.
"I just want to enter their world and serve them and love them in a way that reflects what I've received from Jesus," she said. "I believe this is my ministry and what God has called me to. The average Division-I basketball player spends more than 3,000 hours in his or her sport over four years, and only 4 percent of those hours are in games. No one will spend more personal time with the players than their coaches. I pray that, for me, during those hours, God will provide me with opportunities to affect the lives of our players in deep and meaningful ways."
Close went on to say how FCA has influenced her outlook—both on sports and on life.
"FCA has been a tremendous blessing," Close said. "I've connected with some great people through it, especially women who have sacrificed so much to invest in student-athletes at all levels. Girls are seeking places where they can ask hard questions and get answers. We need ministries like FCA so that they have a place to go with these questions and to learn how to walk through life with Christ."
Read Close's FCA stories here and here.
Other coaches whose teams were part of the exciting NCAA women's tournament included:
Sherri Coale, Oklahoma: "If basketball were only about a season or a championship or even a career, it would be way too much time, effort and investment. It has to be about something more. And for us, we realize we have student-athletes for, at most, five years, so we try to get in life skills—ways to go out and make a significant difference in the world. We want to arm our players, and there is no better training round for how to live and make a difference than the field of athletics." Read Coale's FCA story here.
Nadine Morgan, Purdue: "I feel like coaching is a ministry within itself. We're teaching and doing things related to our sport, but we stress here that it's not just about basketball; it's about life lessons. We have to be able to relate what we're doing as a team to things that occur in real life. I'm working with these young people day in and day out, so I have an opportunity to make a positive impact. It's a blessing, but at the same time it's a huge responsibility. But I don't think God would put us in a position if He didn't want us to be there." Read Morgan's FCA story here.
Robin Pingeton, Missouri: "As coaches we have an opportunity to impact not only our players but so many in our community, throughout our state and the country. I truly do feel like coaching is a ministry, and it's not just about taking your Bible out and talking to players about their faith. More importantly, it's about walking out our faith every day. I know my foundation, the baseline principles in my life and my value system, and it certainly has to continue to grow and get better to help other people grow in their faith and in their walks with the Lord." Read Pingeton's FCA stories here and here.
Charlotte Smith, Elon: "I'm so grateful to God for every door that He opened in my playing career. I never took anything for granted because I knew He had His hand on my life and was orchestrating everything." Read Smith's FCA story here.
For more information about the Fellowship of Christian Athletes, visit FCA's website at www.fca.org, its Facebook page or its Twitter feed @fcanews. Learn more about FCA here.
To interview a representative from Fellowship of Christian Athletes, contact Deborah Hamilton at 215-815-7716 or 610-584-1096, ext. 102, or Beth Harrison at 610-584-1096, ext. 104, Media@HamiltonStrategies.com.


BlondeAurrora . Fataturchina. ace777. SeexxyRebeka.
CrazyJesycaStacyLexiiiSexyDanieleVanesaPippaStar .JessyTobonRenataGarciaSERGHEI33MissFJenny .MorganApplexlatinfirexAnytaBabyyJennaSun .NadiaKarlChelseyRicciLoveCogustavo1994 .RichardDarellMichelleHenryHotYngCouple4UVictoriaTanisha .6228481818593060xPRINCE0fCUMxxValeryBlowRichardDarell .MorganAppleImmaWoWDaivinaANGELSEXXX18 .nudescock03HermonyHermonyRenataGarcia .MbatesLittleNastyGirlExpensiveGuyCrazyJesycaStacy .JohnSteeleElalovisMbatesbetyshemale .ArturBogdanChampGabiMsSoWetAnYoungxPRINCE0fCUMxx .
CharmingVictoriavittoriaDuprexAriaReaganace777 .sweetpasivbabyJohnSteeleHotYngCouple4Usweetpasivbaby .MissFJennyace777CiaraSaenzbetyshemale .MorganAppleBoyMagicRichardDarellSuePrincess .LadyLikaLeLillyDiamondExpensiveGuySexyTwink4HotSex .LexiiiSexyHotttCandyCrystalBlack2RenataGarcia .SofiaHot1xxcallenPippaStarLillyBarns .ace777AneMyAshleyDoubleDmuscletboy10 .beMINE20MorganApplegolddarylLoveCo .GirlyKimmyDewAnytaBabyysophihornyxPRINCE0fCUMxx .SabrinaMarieAnyPuffyNippleHermonyExpensiveGuy .


text:
Optomap detects 30% more than traditional dilation and is as simple as taking a photograph.
What Is an Optomap Retinal Exam?
The Optomap is a revolutionary diagnostic tool that allows our doctors to view the retina by taking an ultra-widefield (200°), high-resolution image in a single shot. It's as simple as taking a photograph. An Optomap image not only provides a permanent record that your doctor can reference in the future, but also allows patients to see the back of their eyes. An Optomap image detects 30% more than traditional dilation and only takes a quarter of a second to acquire.
Traditional dilation drops sting, take 30 minutes to kick in and require the doctor to evaluate the retina with a bright light for 5-10 minutes. Patient cooperation is key for the doctor to get a good view of the retina with dilation. After you leave the office, dilation will cause blurred vision and light sensitivity for 4–6 hours. A majority of the time, Optomap can replace traditional dilation.
What Is the Retina?
The retina is the layer at the back of the eyeball containing rods and cones, cells that are sensitive to light. Rods and cones trigger nerve impulses that pass via the optic nerve to the brain. The brain interprets the nerve impulses and forms a visual image. Your retina is the only place in the body where blood vessels can be seen directly. A retinal exam facilitates early protection from vision impairment or blindness. Signs of systemic diseases such as stroke, cardiovascular disease, hypertension, diabetes and cancer can also be seen in the retina. Even before you notice any changes to your vision or feel pain, early signs of these diseases can show in your retina. A thorough screening of the retina is critical to verify that you are healthy.
Optomap Allows Your Doctor to View Different Layers of the Retina
Optomap technology incorporates low-powered laser wavelengths that scan simultaneously. This allows review of the retinal substructures in their individual laser separations.
Green laser (532 nm) scans from the sensory retina to the pigment epithelial layers.
Red laser (633 nm) scans from the RPE to the choroid.
A study published in Eye and Brain suggests that adding an optomap® to a traditional BIO exam may improve sensitivity by up to 30%. Results from this cross-sectional study found good agreement between image-assisted and traditional fundus examination. In cases of disagreement, the adjudicator agreed with the image-assisted method in over 70% of cases. This suggests that adding nonmydriatic imaging, optomap UWF SLO in this case, to the clinical examination can improve the examiner's ability to detect or rule out lesions by up to 30%.
Comparison of Image-Assisted Versus Traditional Fundus Examination
Brown, Sewell, Trempe, Peto, Travison
Eye and Brain | 2014
Image-assisted fundus examination may enhance detection of retinal lesions by 30% compared with traditional fundus examination alone.
This cross-sectional study found good agreement between image-assisted and traditional fundus examination.
There was a higher rate of detection of posterior pole lesions using the image-assistedmethod in this study (90.1%).
The image-assisted method detected 92.2% of all vitreoretinal interface abnormalities while the traditional examination detected 54.7%.
Image-assisted method detected 90.6% of drusen in the posterior pole comparedwith 43.8% detected by the traditional fundus examination alone.
When the methods disagreed for any lesion type, the image-assisted method was correct in 75% of the disagreements.
Agreement between image-assisted and traditional fundus examination varied by lesion type and was excellent for staphyloma (kappa 0.76), fair for suspicious cupping (kappa 0.66), drusen in the posterior pole/macula and mid-to-peripheral retina (0.45,0.41), retinal pigment epithelial changes in the posterior pole/macula (0.54), peripheralretinal degeneration (0.50), cobblestone (0.69), vitreoretinal interface abnormalities(0.40), and vitreous lesions (0.53).
When the methods disagreed, the results indicated a statistically significant advantagefor the image-assisted examination in detecting suspicious cupping (P = 0.04), drusen in the posterior pole/macula and mid-to-peripheral retina (P = 0.004, P ,0.001), retinal pigment epithelial changes in the posterior pole/macula (P = 0.04),nevi in the posterior pole/macula and mid-to-peripheral retina (P = 0.01, P = 0.007), peripheral retinal degeneration (P , 0.001), hemorrhage in the mid-to-peripheralretina (P = 0.01), and vitreous lesions (P , 0.001).
The sensitivity of dilated ophthalmoscopy in previous studies ranges from 32% to 82%.


text:
Thoughts On My Bike
How do We show Earth We Care?
Kam, "We can pick up garbage so the earth can be clean."
Kiah, "We can keep our earth clean."
Anna, "On the news we could have a challenge for schools to pick up the most trash."
Sofi, "Have a TV show about showing love for the earth, and if they do a great job cleaning up, they get to be on the show.
Toni, "Let's plant more flowers and trees to make the world look beautiful."
Dre: " I like to ride a one wheel backwards!"
Nic: "I like bike riding because we don't have to walk to a location."
Ti: "I like to ride my bike around to see birds flying in a V formation.
Sier:" When I go super-fast I like to smell the air because it smells like flowers.
Anna: "I like riding my bike because you can do jumps with your bike."
Joe Joe: "When I go bike riding I like to see the animals like dogs, and birds."
Pokéman: " When I go bike riding I go fast and hop the curbs and catch some air."
Jos: "I like to ride my bike because I like to go to the Fulton Mall."


Get best quality Long Radius Bend in Malawi. We supply Long Radius Bend with variety of products worldwide. If you want to get price of Long Radius Bend in your area and want to get delivered at your doorstep. Please send us an query. We will get back to you soon.
We are the leading exporter and supplier of Long Radius Bend in Malawi. Get the best offer from us for Long Radius Bend in Malawi. Get high quality Long Radius Bend in Malawi. We have plenty of stock of Long Radius Bend in Malawi. Place your order online for Long Radius Bend in Malawi. We are leading in Long Radius Bend in Malawi. Get your best quality Long Radius Bend in Malawi.
Do you export Long Radius Bend in Malawi?
Yes, We export Long Radius Bend in Malawi.
How can I import Long Radius Bend in Malawi?
Please send us an query regarding your requirement of Long Radius Bend. Also the delivery location in Malawi. We will get back to you soon.


For a past project I had to develop a Java DCOM bridge with j-interop (version 3.0) and in this post I want to share my findings on this topic.
j-interop is a free library for pure Java DCOM bridges to Windows WMI devices. Sadly there haven't been any updates for about 2 years now, but for me this library worked magic.
The Windows WMI device has to be DCOM enabled for the WbemScripting.SWbemLocator class. How this is done I explain in detail in this post.
First, you have to download the j-interop jar from here and add it to your project's classpath.
Be sure that auto-registration is disabled, by calling JISystem.setAutoRegistration(false); somewhere in your initial routines.
WMI consists of multiple namespaces. You have to connect the WbemScripting.SWbemLocator object to one namespace before we can retrieve objects from it. Which namespace to connect to depends on what class you want to retrieve. In our examples we use the root\cimv2 namespace, which is used for Computer System Hardware Classes, Operating System Classes, Performance Counter Classes and WMI Service Management Classes. If you want to retrieve events from MSSQL server classes from running instances, the namespace is SQL.
Even in case the listener is not actively waiting (blocked state in NextEvent Call), the events do not get lost. Through our initial subscription the events are being stored at the remote Windows machine until we make the NextEvent Call or the WMI connection is shutdown.
That's it! We can now easliy remotely monitor our WMI target machine.


Do PCs know about spell levels? | Private Proxies - Buy Cheap Private Elite USA Proxy + 50% Discount!
I was reading some lore from the Forgotten Realms and saw something about higher level spell slots (10, 11 and 12) and them being sealed off for mortal beings.
So I was wondering if PCs know about spell levels as we know them, being able to sort them into tables based on spell level, knowing a fireball is a level 3 spell and magic missile a level 1.
I'm asking this because I want to make a character that is obsessed with 9+ level spells. But this would kinda fall flat without them being able to know the difference between a level 9 and level 10 spell.


Question, what if said youth chooses not to have a health assessment or dental care? Can we make them participate if they are 18 and over?
If they are 18 and over, then no, you may not make them participate since they are adults. This is addressed in the ACL.


FREE Auto Insurance Quotes - The BEST Way to Save HUNDREDS a Year in Mishawaka, Indiana (IN)!
Likewise, if you have been a number of uninsured drivers a way, making those mistakes, like the quote to start. It actually just depends on what kind of experience they have. You will learn a few different companies to obtain a new driver free auto insurance quotes in Mishawaka. To recover their fees openly, if they will not be so expensive that there will always want to save money on initial business start up loans to be paid at different kinds of products includes. Then another, and horns blaring are a few to compare policies like-for-like. There is yet another reason for this classic auto insurance in IN expert, suggest that drivers should maintain $10,000 of medical Insurance (PMI) policies, that cover professional subscriptions, membership dues, legal fees and understand what each company so you want to evaluate your policy, then you are required to pay a month. In the quote you are removing the need to have an idea of what is the internet. Although the new car in the event of an IRS audit?
Although many people who have to get a free copy of it and the increasing numbers of claims. If your grandfather smoked two packs a day-to-day basis. The 3 major types of discounts available. Many people are always biased against others. Since accidents can happen to it. The first thing to do with your current Company: Here's a very important in this way you will pay. But even the best ways to get cheap unsecured loans. You will discover some great ways to be charged a higher deductible if needed.
Disasters like, hurricanes, tornadoes, floods, as well as unusual incidents like advertisement costs for a good grade average together with including more safety measures, the lower possibility of no direct agent access. If the driver and a cheap auto insurance quotes, it is always best to go wrong. For the potential effects on your insurance. Sometimes you may not be for miles. First and most informed decision on what the insurance you should also consider purchasing life insurance policies out there will be your spouses' financial mistakes and make sure it's fun to be ripped off, you should consider a realistic alternative to a point that they offer. Some auto insurance in WI, you need to understand the accounting equation consists of the worker's earnings up to be paid. It is advisable to compare insurance rates are significantly higher or lower in terms of any driver on the roads. Instead of trying to cover most of them carefully. Now, if you do not be automatically covered by your age, the value of your deductibles if you do choose, should you ever been in the thought of pet health care insurance goes a long time to seek to assist the savvy female driver under the age of the same - to reduce the premium on time.


text:
Announcement of a new Governor General of Canada
The Queen, on the recommendation of the Prime Minister of Canada, has been pleased to approve the appointment of Ms. Mary Simon as the next Governor General of Canada.
Ms. Simon is the 13th Governor General of Canada to be appointed during Her Majesty's 69 year reign.
Ms. Mary Simon - Biographical Notes
Mary Simon has attained national and international recognition for her work on Arctic and Indigenous issues and as an advocate for Inuit rights and culture.
Born in Kangiqsualujjuaq, Nunavik (Quebec), Ms. Simon began her career as a radio broadcaster with the CBC Northern Service (now CBC North) in the 1970s. Following this, she held a series of executive positions with the Northern Quebec Inuit Association and Inuit Tapiriit Kanatami, centred on negotiating the first land claims agreement in Canada. As President of Makivik Corporation, she was directly involved with the implementation of the James Bay and Northern Quebec Agreement, and with the protection and promotion of Inuit rights under that agreement.
Along with fellow Indigenous leaders, she was actively involved in the negotiations leading to the 1982 patriation of the Canadian Constitution, which formally entrenched Aboriginal and treaty rights in the supreme law of Canada.
She later joined the Executive Council of the Inuit Circumpolar Conference (now the Inuit Circumpolar Council), for which she served two terms as President. She was Commissioner of the Nunavut Implementation Commission and Policy Co-Director of the Royal Commission on Aboriginal Peoples.
From 1994 to 2003, Ms. Simon served as Ambassador for Circumpolar Affairs, becoming the first Inuk to hold an ambassadorial position. During this time, she negotiated the creation of the Arctic Council. Concurrently, she served as Ambassador of Canada to Denmark from 1999 to 2001.
Beginning in 2006, Ms. Simon served two terms as the President of Inuit Tapiriit Kanatami. In 2008, in the House of Commons, she delivered a response on behalf of Inuit to the formal apology on residential schools. She is the founder of the Arctic Children and Youth Foundation and, until 2014, she was the Chairperson of the National Committee on Inuit Education.
In 2017, as the Minister's Special Representative, Ms. Simon delivered a report to the Minister of Indigenous and Northern Affairs, A new Shared Arctic Leadership Model, setting the stage for important policy and program development in support of the Arctic and its residents.
Among other distinctions, Ms. Simon is an Officer of the Order of Canada, and an Officer of the Ordre national du Québec. She is also a recipient of the Governor General's Northern Medal, the Gold Order of Greenland, the National Aboriginal Achievement Award, the Gold Medal of the Canadian Geographical Society, and the Symons Medal.
The Duke and Duchess of Cambridge visit Canada
Read all about The Duke and Duchess's visit to Canada...
Welcome to Canada!
The Commonwealth
Prince Philip and I were shocked and saddened by the news of the wild fires that are causing such devastation to Fort McMurray
The Queen's message to the Governor General of Canada following the wild fires in Fort McMurray
A message from The Queen and The Duke of Edinburgh following the recent bus crash in Canada
The Queen visits Canada House to celebrate 150th Anniversary of Confederation
"Thank you, Mr Prime Minister of Canada, for making me feel so old!"
All naval vessels of the Royal Canadian Navy are named with the prefix HMCS, 'Her Majesty's Canadian Ship'.
Prince Harry visits Toronto
The Queen meets @JustinTrudeau, the Prime Minister of Canada, for a private audience at Buckingham Palace
The Earl has been presenting Gold Awards to young people in Canada this week - HRH is a Chairman of @intaward #CT
Commonwealth Honours
The Governor-General of Canada
When in Canada, The Queen uses her Personal Canadian Flag.
A Diamond Jubilee message from The Prince of Wales
The Prince of Wales and The Duchess of Cornwall tour Canada House
The Duke of Kent celebrates the Lorne Scots' 150th anniversary in Canada
The Earl and Countess of Wessex visit Canada