"Technology doesn't have to be technical." That sounds totally weird, doesn't it? Almost contradictory, in fact. But if you think about it, it makes sense. And that's our whole point, here. We at Affinity IT deeply believe your IT support needs to make sense. So, we make sure to discuss it with our clients in a way they can easily wrap their heads around. We know after 30 seconds of technical jargon, most people are playing the "Gilligan's Island" theme in their heads and wondering what to buy for lunch. That does no one any good, so we avoid it like the plague.
While we do know our stuff – we're just as human as you are. So we talk to you on a human level about what's going on with your tech. Here's a little more about us, just to show you how human we are.
Yes, we absolutely love what we do. But let's be honest – nothing's better than going home for the day and spending time with our favorite people. We have several policies in place to make sure our people get to spend sufficient time with their people. One of the biggest motivators in employee satisfaction is having enough family and home time, so it's quite important to us they can come in each day to tackle our clients' IT support needs with a smile on their faces.
What brand of computer has the best singing voice? A Dell! HA! We believe in having fun with our work, our coworkers, and our clients. We share stories, anecdotes, and jokes (especially computer-related jokes. Those get brownie points with us). We even love to talk with you about our favorite movies and TV shows we've enjoyed. IT support doesn't have to be technical – and it can also be funny! Here's another one: Did you hear about the new band called 1023MB? They're still waiting for their first gig.
At the end of the day, we can absolutely say we love what we do. Not everyone can say that, and we know how lucky we are to work each and every day in a fantastic industry with incredible clients, doing what we love. We get to use our creativity to architect ideal solutions for businesses, and reap the rewards of happy clients who can work effectively and efficiently.
If you're going to need an IT support company who creates ideal solutions for your company, why not enjoy it? When we partner with you, you're our buddy. We'll have meetings, we'll talk, we'll laugh, and we'll get your technology where it needs to be. Give us a call, and hit us up with your best joke. We'll laugh, we promise.


text:
Good Thing (Vinyl)
Item Vinyl Album
Vinyl Album
The river of soul music flows on deep and strong, and 26-year-old Leon Bridges is immersed in its life-giving current. The Forth Worth, Texas native and Grammy Award-nominated Columbia Records artist released his Gold-selling, debut album, 'Coming Home,' in June of 2015 to critical and public acclaim. "I'm not saying I can hold a candle to any soul musician from the '50s and '60s," Bridges says, "but I want to carry the torch."
2018 sees Bridges release his highly anticipated second album, Good Thing. This March Bridges makes his return to Australian shores playing Bluesfest, as well as headline shows in Sydney and Melbourne that sold out in ten minutes.
1. Bet Ain't Worth The Hand
2. Bad Bad News
3. Shy
4. Beyond
5. Forgive You
6. Lions
7. If It Feels Good (Then It Must Be)
8. You Don't Know
9. Mrs.
10. Georgia To Texas

redpajama_set_name: RedPajamaCommonCrawl


text:
ConservationBytes.com
Conservation research … with bite
CJA Bradshaw
When devils and thylacines went extinct
We've just published an analysis of new radiocarbon dates showing that thylacines (Tasmanian 'tigers', Thylacinus cynocephalus) and Tasmanian devils (Sarcophilus harrisi) went extinct on the Australian mainland at the same time — some 3200 years ago.
For many years, we've been uncertain about when thylacines and devils went extinct in mainland Australia (of course, devils are still in Tasmania, and thylacines went extinct there in the 1930s) — a recent age for the devil extinction (500 years before present) has recently been shown to be unreliable. The next youngest reliable devil fossil is 25000 years old.
So, knowing when both species went extinct is essential to be able to determine the drivers of these extinctions, and why they survived in Tasmania. If the two extinctions on the mainland happened at the same time, this would support the hypothesis that a common driver (or set of drivers) caused both species to go extinct. Read the rest of this entry »
Tags: devils, extinction, palaeo-ecology, palaeontology, Sarcophilus, Tasmanian devil, Tasmanian tiger, Thylacine, Thylacinus
Categories : Australia, decline, extinction, palaeo-ecology, population dynamics
Don't blame it on the dingo
Our postdoc, Tom Prowse, has just had one of the slickest set of reviews I've ever seen, followed by a quick acceptance of what I think is a pretty sexy paper. Earlier this year his paper in Journal of Animal Ecology showed that thylacine (the badly named 'Tasmanian tiger') was most likely not the victim of some unobserved mystery disease, but instead succumbed to what many large predators have/will: human beings. His latest effort now online in Ecology shows that the thylacine and devil extinctions on the Australian mainland were similarly the result of humans and not the scapegoat dingo. But I'll let him explain:
'Regime shifts' can occur in ecosystems when sometimes even a single component is added or changed. Such additions, of say a new predator, or changes such as a rise in temperature, can fundamentally alter core ecosystem functions and processes, causing the ecosystem to switch to some alternative stable state.
Some of the most striking examples of ecological regime shifts are the mass extinctions of large mammals ('megafauna') during human prehistory. In Australia, human arrival and subsequent hunting pressure is implicated in the rapid extinction of about 50 mammal species by around 45 thousand years ago. The ensuing alternative stable state was comprised of a reduced diversity of predators, dominated by humans and two native marsupial predators ‑ the thylacine (also known as the marsupial 'tiger' or 'wolf') and the devil (which is now restricted to Tasmania and threatened by a debilitating, infectious cancer).
Both thylacines and devils lasted on mainland Australia for over 40 thousand years following the arrival of humans. However, a second regime shift resulted in the extinction of both these predators by about 3 thousand years ago, which was coincidentally just after dingoes were introduced to Australia. Dingoes are descended from early domestic dogs and were introduced to northern Australia from Asia by ancient traders approximately 4 thousand years ago. Today, they are Australia's only top predator remaining, other than invasive European foxes and feral cats. Since the earliest days of European settlement, dingoes have been persecuted because they prey on livestock. During the 1880s, 5614 km of 'dingo fence' was constructed to protect south-east Australia's grazing rangelands from dingo incursions. The fence is maintained to this day, and dingoes are poisoned and shot both inside and outside this barrier, despite mounting evidence that these predators play a key role in maintaining native ecosystems, largely by suppressing invasive predators.
Perhaps because the public perception of dingoes as 'sheep-killers' is so firmly entrenched, it has been commonly assumed that dingoes killed off the thylacines and devils on mainland Australia. People who support this view also point out that thylacines and devils persisted on the island of Tasmania, which was never colonised by dingoes (although thylacines went extinct there too in the early 1900s). To date, most discussion of the mainland thylacine and devil extinctions has focused on the possibility that dingoes disrupted the system by 'exploitation competition' (eating the same prey), 'interference competition' (wasting the native predators' precious munching time), as well as 'direct predation' (dingoes actually eating devils and thylacines). Read the rest of this entry »
Tags: Australia, dingo, ecology, regime shift, simulations, Tasmania, Tasmanian devil, Tasmanian tiger, Thylacine
Categories : Australia, climate change, conservation, decline, demography, dingo, exploitation, extinction, harvest, invasive species, mammal, mathematics, modelling, population dynamics, population viability analysis, predator, synergies, trophic cascades
Science immortalised in cartoon
Well, this is a first for me (us).
I've never had a paper of ours turned into a cartoon. The illustrious and brilliant 'First Dog on the Moon' (a.k.a. Andrew Marlton) who is chief cartoonist for Australia's irreverent 'Crikey' online news magazine just parodied our Journal of Animal Ecology paper No need for disease: testing extinction hypotheses for the thylacine using multispecies metamodels that I wrote about a last month here on ConservationBytes.com.
Needless to say, I'm chuffed as a chuffed thing.
Tags: Australia, cartoon, Crikey, First Dog on the Moon, Journal of Animal Ecology, population viability analysis, Thylacine, University of Adelaide
Categories : Australia, conservation, decline, disease, extinction, extinction vortex, habitat loss, harvest, kangaroo, population dynamics, population viability analysis, PVA
No need for disease
It's human nature to abhor admitting an error, and I'd wager that it's even harder for the average person (psycho- and sociopaths perhaps excepted) to admit being a bastard responsible for the demise of someone, or something else. Examples abound. Think of much of society's unwillingness to accept responsibility for global climate disruption (how could my trips to work and occasional holiday flight be killing people on the other side of the planet?). Or, how about fishers refusing to believe that they could be responsible for reductions in fish stocks? After all, killing fish couldn't possibly …er, kill fish? Another one is that bastion of reverse racism maintaining that ancient or traditionally living peoples ('noble savages') could never have wiped out other species.
If you're a rational person driven by evidence rather than hearsay, vested interest or faith, then the above examples probably sound ridiculous. But rest assured, millions of people adhere to these points of view because of the phenomenon mentioned in the first sentence above. With this background then, I introduce a paper that's almost available online (i.e., we have the DOI, but the online version is yet to appear). Produced by our extremely clever post-doc, Tom Prowse, the paper is entitled: No need for disease: testing extinction hypotheses for the thylacine using multispecies metamodels, and will soon appear in Journal of Animal Ecology.
Of course, I am biased being a co-author, but I think this paper really demonstrates the amazing power of retrospective multi-species systems modelling to provide insight into phenomena that are impossible to test empirically – i.e., questions of prehistoric (and in some cases, even data-poor historic) ecological change. The megafauna die-off controversy is one we've covered before here on ConservationBytes.com, and this is a related issue with respect to a charismatic extinction in Australia's recent history – the loss of the Tasmanian thylacine ('tiger', 'wolf' or whatever inappropriate eutherian epithet one unfortunately chooses to apply). Read the rest of this entry »
Tags: Australia, bounty, displacement, exploitation, extinction, farming, hunting, livestock, model, Predation, predator, prey, Tasmania, Tasmanian tiger, Thylacine
Categories : Australia, conservation, decline, deforestation, exploitation, extinction, function, habitat loss, harvest, livestock, mammal, modelling, population dynamics, population viability analysis, predator, PVA, synergies
Ghost extinctions
The Philippine bare-backed fruit bat (Dobsonia chapmani; body size = < 220 mm, < 150 g; IUCN status: 'Critically Endangered A2cd') is endemic to lowland rain forests [top habitat image] from Negros and Cebu islands. This species of flying fox had been missing from the 1970s and was declared extinct in 2002 (34). In May 2003, five specimens [one shown in the picture above] were trapped in night nets in the Calatong forest (Negros Island), a ~ 1,000-ha fragment of secondary rain forest and agricultural lands [bottom habitat image] (35). The species is reliant on fruit-bearing vegetation and caves for feeding and roosting, respectively. As with many other Philippine bats, it suffers from habitat degradation and hunting. The family Pteropodidae comprises > 150 species. Despite their Draculian look, they all feed on fruits and nectar, and act as important plant pollinators (36), as well as disease vectors such as Ebola virus (37). Flying foxes are distributed in the tropics and subtropics from the Eastern Mediterranean, through the Arabian Peninsula, Asia, Australia, and many islands of the Indian Ocean. Photos courtesy of Ely L. Alcala.
Jared Diamond (1) coined the expression 'evil quartet' for the four main human causes of species extinctions: habitat loss/fragmentation, overkill, introduced species and extinction chains [with climate change and extinction synergies (2), the updated expression would be 'evil sextet"]. However, one third of 'extinct' mammal species has been 'found' again. Recent studies reveal that the probability of rediscovery depends on the cause of extinction.
Arriving in a city to search for an old friend, I would first look in the suburb where he lived, the pub where we enjoyed a drink and some music, or the park where we used to play football. But if my friend was an outlaw, or had recently gone through a traumatic experience, my chances of finding him at his favourite spots would shrink.
If, instead of a friend, we are searching for the last survivors of an extinct-declared species, surveys also tend to take place in the habitat in which the species was previously found. Such a strategy rests on the classical hypothesis that, given the spatial distribution of a species, its gradual decline must occur from the periphery to the core of its distribution ('range collapse') where, in theory, the habitat should be of better quality and the number of individuals higher (3). In contrast, recent work supports that the trajectory of demise of threatened vertebrates progresses from the core to the periphery ('range eclipse') (4), because many perturbations make their way as a progressive wave, e.g, fire, logging or urbanisation.
Diana Fisher (5) supports the 'range eclipse' hypothesis for 'extinct' mammals which have been rediscovered. She quantifies that 60% of the new records are made from peripheral habitats, mainly when the principal cause of extirpation is habitat loss. Not only that, on average species are rediscovered at altitudes 35 % higher than historical records, and only in 5 % of the cases at the locality where it had been last seen.
Tags: Australia, biodiversity, detection, extinction, Jared Diamond, range collapse, range eclipse, species, Thylacine
Categories : Australia, biodiversity, climate change, conservation, decline, extinction, habitat loss, species-area curve
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Corresponding author. E-mail address: yangxl@cau.edu.cn (X. Yang).
Abstract: Allatostatins (ASTs), a family of insect neuropeptide, can inhibit juvenile hormone (JH) biosynthesis by the corpora allata (CA) in Diploptera punctata, and therefore be regarded as potential leads for the discovery of new insect growth regulators (IGRs). But several shortcomings, such as their sensitivity to peptidases and high cost, impeded their practical application in pest management. In order to discover new IGRs, one ASTanalog B1 possessing non-peptide group was discovered with high ability to inhibit JH biosynthesis in vitro (IC50:0.09 μmol/L) in our previous studies. In the present work, two series of B1 analogs with different substituents on the N-terminus region were designed and synthesized. The result suggested that benzene showed better activity than other heterocycles, and the para-substitution on the benzene was beneficial for activity. Moreover, analogs with logP value over 2.0 exhibited good activity, which indicated the hydrophobicity is important to the bioactivity. Three dimension quantitative structure-activity relationship (3D-QSAR) studies were performed to highlight the structural requirements of ASTanalogs, which demonstrated introduction of bulkier substituents on the N-terminus would increase the activity. Analog II12 (IC50:0.08 njmol/L) exhibited similar inhibitory activity to the lead B1, but its synthetic route was simpler than B1. Therefore, II12could be used as a new lead compound for the discovery eco-friendly IGRs.
Thanks to the virtue of high potency, good selectivity and ecofriendly safety, insect growth regulators (IGRs) are regarded as 'the ideal pesticides in the st century . The discovery of new IGRs has therefore become increasingly important in pest control both in agriculture and public health. The FGLamide allatostatins (FGLaASTs), originally isolated from the cockroach Diploptera punctata in 1989, have 6-18 amino acids and inhibit juvenile hormone(JH) biosynthesis by the corpora allata . Allatostatins (ASTs) also exhibited pleiotropic functions including modulation of myotropic activity in both gut and dorsal vessel , inhibition of vitellogenin production in the fat body , stimulation of carbohydrate enzyme activity in the midgut . With these abilities to influence a number of physiological processes, especially inhibition of JH biosynthesis in some insect species, ASTs were regarded to be potential leads for the discovery of new IGRs.
However, some shortcomings, such as their susceptibility to both exo- and endopeptidases in hemolymph and tissues of insects and high production cost, preclude their application in pest management . To find analogs that overcome these limitations while retain activity, structural modifications and structureactivity relationships (SARs) have been carried out in recent years. There are several susceptible hydrolysis sites in the core pentapeptide of the FGLa-ASTs which shared a common conserved C-terminal sequence Y/FXFGL-NH2 (X = A, N, G, and S) for activity . The primary site is between Y/F and X residue, which was susceptible to cleavage by the enzymes of hemolymph [8, 9]. Replacing the specify amino acids with non-amino acid, Nachman had synthesized some ASTs analogs which retained the ability of inhibition JH biosynthesis and displayed resistance to degradation . Kai replaced Y with a non-peptide structure (aromatic group) and obtained some analogs with enhanced resistance to peptidase hydrolysis . Using the peptidomimetics strategy, Xie found a new simple mimic B1 for T/YXFG, with higher activity than the lead core pentapeptide . Previous study demonstrated that these positions tolerated a range of non-amino acid replacement.
Introduction non-amino acid groups can not only protect peptidase-susceptible sites but also reduce the production cost. With the purpose to study the substituents effects of the N-terminus region on JH inhibitory activity and to explore the structure-activity relationship as well as to highlight the structural requirements of AST analogs for further discovering new analogs with higher activity and simpler structure, we designed two series of ASTs analogs by modifying the N-terminus region of lead B1 via replacing 1H-benzotriazole with aniline, heterocyclic amines or other substitutes (the design strategy is shown in Fig. 1). The target compounds were prepared via a simpler synthetic route in the present work and their structures were confirmed by 1H NMR, 13C NMR and HRMS. Their inhibition of JH biosynthesis against Diploptera punctata was evaluated in vitro and the preliminary structure-activity relationship was analyzed. In addition, 3D-QSAR studies were performed to explore the vital factors for designing new IGRs candidate.
The synthesis of analog B1 (1) and analog II12 (2) was illustrated in Scheme S1 (Supporting information). The rest analogs were obtained using the same synthetic route (2). Leu with resin was synthesized from Rink amide-AM resin (1 equiv.) using the standard Fmoc/tBu chemistry and HBTU/HOBt protocol [12, 13]. Fmoc–Leu–OH (3 equiv.) was activated with HBTU (3 equiv.), HOBt (3 equiv.) and DIEA (6 equiv.) in DMF for 5 min, and couplings were run for 4 h. Removal of the N-terminus Fmoc group from the residues was accomplished with 20% piperidine in DMF for 20 min. Compound 2 was obtained from compound 1 (8 equiv.) which was coupled to the Leu with resin with Dic (4 equiv.) in DMF for 4 h at room temperature . The product with the resin was prepared by the acyl reaction of compound 2 with 4-aminobenzotrifluoride in DMF for 8 h, and then the product was cleaved from the resin with TFA containing 5% water for 2.5 h at room temperature. The crude compounds were purified on a C18 reversed-phase preparation column with a flow rate of 10 mL/min using acetonitrile/water (50:50) at room temperature. UV detection was at 215 nm. The physical and identification data (melting point, 1H NMR and HRMS of all target compounds and 13C NMR of typical analogs I2 and II12) are given in the Supporting information.
The method involves the acyl reaction and solid phase peptide synthesis. Using the reported method , the lead B1 was obtained totally in nine steps and twice purification. The key intermediate compound 2 was cleaved with TFA and then the solution was purified on a C18 reversed-phase preparative column and freeze-dried in vacuum. The crude target compound B1 was obtained by repeating above purification steps. In the present work with purpose to simplify the route and reduce the cost, the compound 2 was directly reacted with 4-aminobenzotrifluoride followed by cleavage and purification, and we successfully obtained the target compound II12. Comparing to lead B1, the route of II12 was shortened from nine steps with twice purification to eight steps with once purification. Moreover, the dosage of HPLC grade solvent used in target compounds preparation was reduced by half.
Natural ASTs are susceptible to inactivation in vivo as a consequence of hydrolysis by hemolymph and poor penetration through the insects. The primarily hydrolytic site of the core pentapeptide between the residues Y/F-X and the other hydrolytic site such as G-L was also detected . Analogs with modification and replacement of amino acids at the hydrolysis not only showed resistance to peptidases but also retained their bioactivities. In our previous study , analog B1, a new mimic for Y/FXFGL in which Y was replaced with 4-(1H-benzo[d][1,2,3]triazol-1-yl)-4-oxobutanoic acid, showed good inhibition activity without hydrolytic site. To find new analogs with higher bioactivity and lower cost, further optimization on B1 was carried out in present work. As shown in Fig. 1, the first step of the strategy was to replace the N-terminus 1H-benzotriazole with aniline and heterocyclic amines (Series I). The bioassay result indicated that analog I1 with N-terminus containing benzene showed the best activity. We subsequently selected I1 as the second lead, and a series of analogs Series II) with different substituents on benzene at the N-terminus were designed and synthesized to explore the substituent effect on the benzene ring.
According to the results shown in Table 1, most of the target analogs showed obvious ability to inhibit JH biosynthesis by the corpora allata (CA) of D. punctata in vitro at 1 ×10-5 mol/L. Analogs showing inhibition rate more than 70% were chosen to determine their IC50 values. The results indicated that these analogs had different potencies owing to vary modification at N-terminus. Series I (I1–I5), in which aniline and heterocyclic amines mimicked the 1H-benzotriazole region, showed lower activity than B1. However, analog I1 showed the best activity compared to other analogs of series I and therefore was chosen to be the second lead for further optimization. Fortunately, we found that the activities of series II were higher than that of series I. Fig. 2 clearly exhibited that different positions of substituents on the benzene ring at N-terminus can lead to different activities. In particular, substituents in the phenyl para-position were beneficial for activity compared with meta- and ortho- substituents (p-F (II6) > m-F (II5) > o-F (II4)). Meanwhile, in the same para-position on the phenyl ring, the electron-withdrawing substituents contributed to better activity than that of electron-donating groups, such as (p-CF3 (II12) > p-Br (II10) > p-Cl (II8) > p-CH3 (II3)). However, compound II6 with p-F was an exception due to the following reasons: (1) The activity might be also associated with its steric effect and the radius of fluorine atoms is smaller than methyl group; (2) The hydrophobicity capacity may be benefit for its activity and the lipophilicity of II6 was weaker than that of II3. Compound II12 (p-CF3) exhibited the highest activity (IC50: 0.08 μmol/L), which was close to the st lead B1 (IC50: 0.09 μmol/L).
In the previous work , it was supposed that the potency of the AST analogs may be related to their lipophilicity. To elucidate the relationship between hydrophobicity and the inhibition activity, the logP values of target analogs were calculated by the prediction system (Table 1). The results obviously exhibited that these AST analogs with logP values less than 2.0 exhibited poor activity (I3, logP = 1.9) and (I5, logP = 0.76). Analogs with logP more than 2.0 showed visible activity. This indicated that a suitable hydrophobicity may be important to activity. Possibly, these analogs with strong lipophilic capability may easily penetrate the cell membrane and interaction with the Dippu-AST receptor, consequently exhibit potent effects. However, the above hypothesis needs more evidences to validate.
The results of CoMFA and CoMSIA model are showed in Table S1 (Supporting information). The predicted r2 for CoMFA (rtest2 = 0.878) was lower than that for CoMSIA (rtest2 = 0.891), indicating that CoMSIA had better predictive ability. The scattered plot of the predicted activity data versus the experimental data showed in Fig. S2 (Supporting information) and the values showed in Table S2 (Supporting information). The good correlations prove the robustness and good predictive ability of the optimal CoMSIA model.
Two significant effects map (Fig. 3A (steric) and Fig. 3B (hydrophobic)) were built with CoMSIA method. In the region A (N-terminus) of Fig. 3A, the steric contours of the CoMSIA displayed a large green contour, which indicated the favorable effect of bulky groups on increasing the biological activities of molecules. For instance, bulkier groups such as -CH3 (II1-II3 with pIC50 = 6.040, 6.545, 6.710) in contrast to -H (I1 with pIC50 = 5.640) in region A could increase the biological activities. This is according with above result which the activity of analog II3 with p-CH3 was higher than that of II6 with p-F. This was also observed among molecules II3-II12 having F, Cl, Br, CF3 group respectively. The larger the substituent, the better activity it has. The order of inhibition activities are p-CF3 (II12) > p-Br (II10) > p-Cl (II8) > p-F (II6) and m-CF3 (II11) > m-Br (II9) > m-Cl (II7). From Fig. 3B, two white contours in region C (2 site amino acid at N-terminus) and carbon terminus respectively, indicated that introduction of hydrophilic substituents in these regions will benefit for inhibitory activity. That further pIC50 values are needed to illustrate this model.
Two series of novel peptidomimetic analogs were designed and synthesized. The activity of inhibition JH biosynthesis showed that most analogs exhibited considerable activity, especially analog II12 (IC50: 0.08 μmol/L) exhibited similar activity to the lead compound B1 (IC50: 0.09 μmol/L). The preparation procedure was simplified and the production cost was reduced roughly. Primary structureactivity relationship revealed that para-substituent had an obvious influence on activity. The proper lipophilicity logP over 2) is favorable for activity. 3D-QSAR models were obtained with high accuracy and predictive ability. The CoMSIA analysis indicated that a significant steric arrangement, where bulkier substituents are aligned on the N-terminus region, positively correlates with activity. In addition, introduction of hydrophilic substituents in 2 site amino acid at N-terminus will be benefit for inhibitory activity. These results provide useful clues for further chemical modifications and the in vivo activity of some promising compounds will be tested in our next optimization work on discovering potential IGRs.
We are very grateful to Professor Stephen S. Tobe for his kind help on bioassay of JH production inhibition in vitro. This study was financially supported by the National Natural Science Foundation of China (No. 21372257) and the grants from the National Key Research and Development Plan (No. 2017YFD0200504).
Supplementary data associated with this article can be found, in the online version, at https://doi.org/10.1016/j.cclet.2017.11.022.
S.M. Olieff, H.J. Mosson, J.P. Edwards, et al., Int. Pest Control 39 (1997) 44-45.
A.S. Ripka, D.H. Rich, Curr. Opin. Chem. Biol. 2 (1988) 441-452.
W.C. Chan, P.D. White, Fmoc Solid Phase Peptide Synthesis:A Practical Approach. New York: Oxford University Press, 2000.


– Updated advertisements for the SmackDown/ECW tapings this Tuesday night in Fresno, CA at the Save Mart Center include Edge vs. Jeff Hardy in a Steel Cage match, The Undertaker vs. Triple H vs. Big Show vs. Vladimir Kozlov and Matt Hardy vs. Rey Mysterio.
Rey always appears when WWE is in the area and the Fatal Fourway sounds like it may actually happen, seeing how it's the final SmackDown before No Way Out and the Elimination Chamber.
Next week's ECW on Sci-Fi will not be taped Monday night before RAW, but will air live on Tuesday night before the SmackDown tapings begin.
If you plan on attending Tuesday's tapings in Fresno, please e-mail me so we can get a report.
BIG Storyline for Undertaker, Another WM 25 Match Leaked, Who's Really Coming to The Legacy? MORE!


Year 7 pupils once again joined hundreds of other schools at the yearly STEM extravaganza. Our pupils were treated to demonstrations of experiments to inspire them into a technological future. Pupils climbed inside racing cars, construction vehicles, F1 racers and even rocket cars. Our children learned how technology in medicine and had the chance to control a plethora of robotics. Our pupils presented themselves amazingly with their questions, behaviour and willingness to take part. Thank you to all staff involved in organising another amazing day.
Year 7 and Year 8 pupils travelled to Birmingham for Britain's biggest STEM event. Children from all over Britain were treated to interactive displays of the latest technologies, including 3D printers, robotics, coding, sensors, medecine and many more.
Pupils had the opportunits to sit in ambulances, JCB vehicles and aeroplanes. Stages at the event ranged from creating music with code, dangerous creatures to the worlds loudest burp. Christ Church pupils excelled themselves and were arrived back with bags full of free gifts.
The science department has recently had the great pleasure of watching 8 chicks hatch from eggs. As part of the Year 5 life cycles topic we observed as the chicks emerged from their eggs in an incubator and then witnessed them grow into healthy young birds. The three ladies have been safely housed with Mrs Graham's family and we hope to follow their progress as they develop.
As part of STEM activities within the science department Mrs Miller has recently taken 8 girls from Year 8 to 'Here come the girls' at Staffordshire University. The event is dedicated to helping young girls understand the opportunities available to them in science, technology, engineering and maths. The girls had a great day, taking part in programming, technology and engineering projects with local businesses and heard an inspiring talk from a young woman currently taking part in an apprenticeship with JCB.
Year 6 took an alternative approach to understanding how living things can impact on their environment. During lesson they created 'wild art' using materials from the school garden to depict how environments can be changed in both a negative and positive fashion. They were able to describe their 'art' beautifully using what proved to be extensive science knowledge. A creative approach that really got the children thinking!


Over the past couple of years, I have played around with gluten-free and paleo holiday dessert recipes and now have several simple ones in my repetoire for Thanksgiving day. These pecan pie bars are sure to delight all. No longer will you have to sit wistfully watching your relatives each gluten-filled desserts on Thanskgiving.
To make crust, preheat oven to 350F and grease an 8 x 8" pan. Mix crust ingredients together and press into pan. Bake for 15 minutes, until crust starts to turn brown. Remove from oven and allow to cool.
For filling: In a small pot, mix together the oil, maple syrup, honey, and vanilla. Bring pot up to a boil and simmer for about 5 minutes, whisking frequently.
Remove from heat and let cool to room temp. You can put pot in fridge or freezer to accelerate cooling process.
Meanwhile, toast the pecans in a pan on medium heat for about 5-8 minutes or until they smell like roasted pecans, stirring frequently. Remove from heat.
Once sugar-oil mixture is cool, mix in the egg and tapioca starch. Then mix in pecans until well combined. Pour into the cooled crust and distribute evenly.
Bake at 350F for about 20 minutes or until the filling begins to set and loses its shine. Remove from oven and let cool. Before serving, chill in the fridge for at least 1 hr. The colder they are, the easier they are to cut and serve.


text:
Dag Alveng (ur. 9 września 1953 w Oslo) – norweski fotograf.

Działalność artystyczna

Wystawy indywidualne

 1979 - Galleri 1, Bergen
 1979 - Fotogalleriet, Oslo
 1979 - Gallery 7/Club 7, Oslo
 1981 - Galleri KT, Kongsberg
 1982 - Kunstmuseet, Trondheim
 1982 - Preus Fotomuseum, Horten
 1985 - Wang Kunsthandel, Oslo
 1986 - Kunstnernes Hus, Oslo
 1987 - Preus Fotomuseum, Horten
 1988 - Museum for Fotokunst, Odense
 1989 - Opsis Gallery, Nowy Jork
 1991 - Fotogalleriet, Oslo
 1993 - Holly Solomon Gallery, Nowy Jork
 1993 - Galleri Riis, Oslo
 1994 - Henie-Onstad Kunstsenter, Høvikodden
 1994 - Portland School of Art, Portland
 1998 - Galleri Fotografia, Oslo
 2000 - The Gallery of the Center of Modern Art, Warszawa
 2001 - Sprengel Museum Hannover, Niemcy
 2001 - Narodowe Muzeum Sztuki, Architektury i Projektowania, Oslo
 2003 - Deborah Bell Photographs, Nowy Jork
 2003 - Galleri Brandstrup, Oslo
 2007 - Blomqvist, Oslo
 2008 - Deborah Bell Photographs, Nowy Jork
 2009 - Caixa de Economia Galeria da Paulista, São Paulo
 2009 - Benedito Calixto Museum, Santos
 2012 - Drammens Museum, Drammen
 2012 - Galleri Brandstrup, Oslo
 2013 - Haugar Vestfold Kunstmuseum,Tønsberg

Książki i albumy fotograficzne
 «Sommerlys», tekst Per Bjarne Boym, Oslo 2013
 «Racing», tekst Åsmund Thorkildsen, Joachim Førsund, Forlaget press, 2012
 «One Shot Each – Humor Belyst», Museet for Fotokunst Brandts, Odense, 2007
 «This is MOST important – The New York Multiple Exposure Series», Forlaget Oktober, 2003
 «Summer Light», tekst Robert Adams, Eva Klerck-Gange i Thomas Weski, Forlaget Oktober, 2001
 «Layers of Light», Ex Libris Forlag, 1995
 «The Yard at Solheimsviken», tekst Kjartan Fløgstad, Hanne Müller, Alma Mater, 1990
 «Asylum», tekst Susan Kismaric, Koks Forlag, 1987
 «54 Mayo Road», Ikaros, Oslo, 1978
 «Photographs from the Real World», Den norske Bokklubben i anledning OL på Lillehammer
 «Bilder av menn», tekst  Trond-Viggo Torgersen, University Press, Oslo, 1985

Nagrody
 Young Photographers Award, Arles1983
 Photographers Gold Award, Norges Fotografforbund 1998

Kolekcje
Prace artysty znajdują się w zbiorach m.in.:
 Nowojorska Biblioteka Publiczna, Stany Zjednoczone Ameryki Północnej
 The Hasselblad Center, Göteborg, Szwecja
 Yale University Art Gallery, Stany Zjednoczone Ameryki Północnej
 The Metropolitan Museum of Art, Nowy Jork, Stany Zjednoczone Ameryki Północnej
 Museum of Modern Art (MoMA), Nowy Jork, Stany Zjednoczone Ameryki Północnej
 Sprengel Museum, Hannover, Niemcy
 Museum Folkwang, Essen, Niemcy
 Francuska Biblioteka Narodowa, Paryż,Francja
 Stedelijk Museum, Amsterdam, Holandia
 Moderna Museet, Stockholm, Szwecja
 Narodowe Muzeum Sztuki, Architektury i Projektowania, Oslo, Norwegia
 Henie-Onstad Art Center, Høvikodden, Norwegia
 Museet for Fotokunst, Odense, Dania
 The National Museum of Photography – Preus Photomuseum, Horten, Norwegia
 The Art Collection of the City of Oslo, Stenersenmuseet, Norwegia
 The Art Collection of The Norwegian Council of Cultural Affairs, Norwegia

Linki zewnętrzne
 Strona domowa
 Wywiad

Norwescy fotografowie
Urodzeni w 1953
Ludzie urodzeni w Oslo

redpajama_set_name: RedPajamaWikipedia


text:
Hylarana malabarica es una especie  de anfibios de la familia Nyctibatrachidae.

Distribución geográfica y hábitat
Es endémica de la India. Su rango altitudinal oscila entre 0 y 1500 msnm.

Referencias

 Biju, S.D., Dutta, S. & Inger, R. 2004.  Hylarana malabarica. The IUCN Red List of Threatened Species. Version 2014.3. Acceso: 27 de abril de 2015.

Enlaces externos

malabarica
Anfibios de India
Fauna endémica de India
Animales descritos en 1838
Taxones descritos por Johann Jakob von Tschudi


text:
Zeljko Jerman
Group of Six Authors
Mladen Stilinovic
EXAT 51 & New Tendencies
Sanja Ivekovic
Avantgarde Covers
Miroslav Krleza
Literature Memorabilia
Radovan Ivsic
Bibliofil Edition
Marko Ristic
Miljenko Jergovic / signed
Ljubomir Micic
Ivo Andric
Ivana Brlic Mazuranic
Gorgona /
Victor Vasarely: Gorgona 4 (CRO)
Croatian language edition. Edition privée, Josip Vaništa, Zagreb, Yougoslavie. Exemplarie 113 / 250
Izdanje na hrvatskom jeziku.
Screenprinted cover and screenprinted insert
page (each): 8 1/4 x 7 9/16" (21 x 19.2 cm)
Vasarely's Gorgona includes several drawings from that period and the author's text.
Fine condition.
The Gorgona Group, was a Croatian avant-garde art group which consisted of artists and art historians: Dimitrije Bašičević-Mangelos, Miljenko Horvat, Marijan Jevšovar, Julije Knifer, Ivan Kožarić, Matko Meštrović, Radoslav Putar, Đuro Seder, Josip Vaništa, operated along the lines of anti-art in Zagreb between 1959 and 1966. Beside individual works linked to traditional techniques, the members proposed different concepts and forms of artistic communication and published the anti-magazine Gorgona - 11 issues.
Autor: Victor Vasarely
Izdavač: Josip Vaništa, Zagreb
Izdanje: prvo/first
Format: 20,8x19.2
Copyright © 2019 Bibliofil. All rights reserved.


text:
A Critical Forum on Media and Culture
About Flow
Technical credits
Former editors
Over*Flow: COVID-19 Conversations
Your Mascot Could Never: The Effectiveness of Benny the Bull on Tiktok
James Bingaman / University of Delaware
October 1, 2020 James Bingaman / University of Delaware Leave a comment
The Chicago Bull's Mascot: Benny the Bull
In an article identifying the biggest sports media trends, global marketing giant, Nielsen, listed "capturing the attention of Gen Z" (Nielsen Sports, n.d., para. 8) as one of the trends to watch out for in 2020. Gen Z — affectionately named "zoomers" — are those born after 1996 (Parker & Igielnik, 2020) and are often associated with having their heads buried into their phones or taking part in the latest dance trend. Currently, a lot of discourse surrounding Gen Z is related to their use of TikTok, which is currently the top downloaded app of 2020, and the 6th largest social media site (Sehl, 2020). With almost half of all users being below the age of 24 (Sehl, 2020), TikTok has almost become a necessity for creators, brands, and organizations to reach out to this younger generation. Sports organizations are no different. Effective communication via social media is integral to the success of sports organizations (Siguencia et al., 2016) so being able to successfully navigate this new social media environment should be one of the main goals for every sports organizations' media strategy in 2020 and beyond. This short essay will focus on the innovative way that the Chicago Bulls have utilized TikTok by focusing less on sports and instead focusing on an often underappreciated source: their mascot, Benny the Bull.
Benny the Bull
Beginning in the late 1960s, Benny the Bull became the National Basketball Association's (NBA) first mascot and has enjoyed unrivaled national and international popularity ever since (Borrelli, 2019). Already a success on other social media platforms, Benny the Bull has transcended the sports realm and has become somewhat of an influencer on TikTok, partaking in collaborations with some of the platform's biggest stars (e.g. Charlie D'Amelio). Mascots having social media accounts is not a new phenomenon as teams will often use mascots online to increase emotional connectivity with fans (Wandel, 2018), especially through TikTok. Benny the Bull has already led other teams to use their mascots more frequently on TikTok (Moran, 2019). However, Benny stands out from the rest. By the end of August 2020, Benny had 2.9 million followers and 46.6 million likes, whereas the Chicago Bulls had just shy of 400 thousand followers and 1.6 million likes. There are several reasons why Benny has thrived on TikTok, however, this piece will look at three main reasons: the influence of dancing on TikTok, the difference in how the platform is used, and the formation of parasocial connections between Benny and users.
@bennythebull
@charlidamelio @dixiedamelio @addisonre
♬ Bagaikan Langit(cover) – _ucil👑
@bennythebull's TikTok, 2/15/20.
LeBron James won't "renegade"
According to Siobhan Burke (2020) of The New York Times, "TikTok has become a wildly popular global platform for dance, especially among teens, with tools that make it easy to film yourself dancing to music, integrate special effects and share the results" (para. 5). Although TikTok is a platform that welcomes creators from all backgrounds and styles, overwhelmingly, dance has taken over as the predominant art form. Knowing that these short little dance routines thrive, it's easy to see why a mascot could be successful in this kind of environment. We are used to seeing mascots dance. We see it in stadiums, arenas, and on our televisions when we watch sporting events. Even the official Benny the Bull website (Benny the Bull, n.d.) lists "dancing" as Benny's number one activity. Although the identity of Benny the Bull is kept under wraps, the most recent performer to don the red fur was Barry Anderson (who has since retired after 12 years as Benny), a former theater and dance student at the University of Montana known for his high-flying routines (Borrelli, 2019). The Chicago Bulls took this high-flying, dancing red bull virtual and found a new, niche home that catered towards that kind of act.
‼NEW DANCE‼ Who do you want to see do it next? ##BullsBMOChallenge ##dance
♬ Benny Dance Challenge – chicagobulls
Despite his presence in a viral video from 2013 of the Miami Heat taking part in the Harlem Shake trend, along with some of the goofy antics with his family that he posts on Instagram, it's hard to see LeBron James — or any major athlete for that matter — taking part in weekly dance trends on TikTok (like the video shown above). The renegade dance routine, created by Jalaiah Harmon, went viral on TikTok earlier this year and was even featured during NBA All-Star weekend (Madu, 2020). Sure, athletes could post a video of themselves doing the renegade on their personal accounts, but official sports accounts often use footage from games, interviews, or clips from extended pieces that are posted across all social media platforms, so taking the time to teach LeBron routines like the video above or to ask him to give up time to dance seems unlikely. Likewise, front office members that might have the time to dedicate to dancing on TikTok won't grab the same attention of an audience as a professional athlete would. On a platform where dancing thrives, the only logical answer is to use the mascot, not only because they have a history of dancing, but because this is a more casual way to engage with fans rather than getting a professional athlete involved.
TikTok is not like any other platform
TikTok is not like other social media platforms. Other social media platforms like Twitter are used to build relationships and share information with others via text (Wang & Zhou, 2015). In what could be seen as a competitor, Instagram relies on users sharing pictures (Waterloo et al., 2018) that fall within eight categories — friends, food, gadgets, captioned photos, pets, activities, selfies, and fashion (Hu et al., 2014). While users can also post videos on Instagram, TikTok is different in that it's entirely predicated on being a video platform. Unlike photos, video can increase immersion and interaction, ultimately extending the experience for users (Dinhopl & Gretzel, 2014). Mobile videos that are shot in the first-person are more engaging as they increase immersion, social presence, and entertainment for users (Wang, 2020). Fans engaging with Benny the Bull on TikTok are not just doing so through photos (Instagram) or text (Twitter) but are instead absorbed into a world where, for just a moment, mascots are not people in costumes but are performers and characters they can connect with.
Individual vs. Team
Parasocial interaction refers to the perceived one-way relationship that exists between a viewer and a media figure that can be analogous to real relationships (Weiss, 1996). Social media has afforded users with new avenues to connect and engage with their favorite media figures (Pegoraro, 2017) including athletes or other sports figures (Kim & Song, 2016). There is no reason to leave mascots off this list. If people can become connected to fictional characters on television, there is no reason they cannot become attached to a mascot. As demonstrated with the image below, other users respond to Benny in a similar way that they would to other creators. This is not the type of comment you would see with a branded account, but rather a social interaction that is common among online friends and followers. Having an individual, even if it's a mascot, to respond and connect with makes it much easier to form these parasocial relationships. This is where immersion is important. Although Benny has other social media accounts, none afford him with the immersive experience that TikTok does.
TikTok users have formed a parasocial relationship with Benny
Having people connect with Benny is smart for the Chicago Bulls. Firstly, with the official account showing multiple players on a day-to-day basis, it would be harder for fans to form a parasocial bond. That kind of attachment and identification with the team looks more like fandom than a parasocial relationship. Secondly, the Bulls don't have to inundate fans of Benny the Bull with highlight clips or sport-specific content. Instead, they just let Benny do his thing, yet still reap the benefits of the Chicago Bulls branding, social media engagement, and potential crossover of new and younger fans. The Benny the Bull TikTok account allows the team to connect with fans at a parasocial level, which is something that's difficult to do as a sports team.
Although Benny the Bull is associated with the Chicago Bulls, the account itself is not as sports-focused as the primary TikTok account of the Bulls, expanding the potential for users not interested in sports to become connected to the character. Mascots have always been used as a form of branding (Vrabel, 2017), and with TikTok offering a new platform for sports organizations to foster existing relationships, promote their brand, and appeal to new fans (Su et al., 2020), mascots have a new and exciting outlet. The dance-focused, sometimes silly TikTok platform, is perfect for characters like Benny the Bull to successfully transition from being obscure relics of the in-stadium sports experience to being integral for continued success among Gen Z and social media sites dedicated to creativity. With sports organizations poised to use TikTok as part of their media strategy, don't be surprised to see your teams' mascot dancing along to the newest trend.
@bennythebull's TikTok, 2/15/20
TikTok users have formed a parasocial relationship with Benny (Author's screengrab)
Benny the Bull. (n.d.). About Benny. http://iwantbenny.com/about-benny.html
Borrelli, C. (2019, March 30). Benny the Bull has accompanied a mayor to China, topped a Forbes list and been arrested at the Taste of Chicago: And that's only part of his story. Chicago Tribune. https://www.chicagotribune.com/sports/bulls/ct-spt-bulls-benny-the-bull-history-20190330-story.html
Burke, S. (2020, April 29). Some pros let it go on TikTok: 'Is this the future?' The New York Times. https://www.nytimes.com/2020/04/29/arts/dance/tiktok-dance-challenges.html
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Horton, D., & Wohl, R.R. (1956). Mass communication and para-social interaction: Observations on intimacy at a distance. Psychiatry, 19, 215-229. https://doi-org/10.1080/00332747.1956.11023049
Hu, Y., Manikonda, L., & Kambhampati, S. (2014). What we Instagram: A first analysis of Instagram photo content and user types. In Proceedings of the 8th International Conference on Weblogs and Social Media, ICWSM 2014 (pp. 595-598). (Proceedings of the 8th International Conference on Weblogs and Social Media, ICWSM 2014). The AAAI Press. https://www.aaai.org/ocs/index.php/ICWSM/ICWSM14/paper/viewFile/8118/8087
Kim, J., & Song, H. (2016). Celebrity's self-disclosure on Twitter and parasocial relationships: A mediating role of social presence. Computers in Human Behavior, 62, 570-577. https://doi.org/10.1016/j.chb.2016.03.083
Madu, Z. (2020, February 17). The NBA invited Jalaiah Harmon to perform 'renegade' and showed how to address appropriation. SB Nation. https://www.sbnation.com/nba/2020/2/17/21141239/renegade-dance-nba-all-star-game-jalaiah-harmon-cultural-appropriation
Moran, E. (2019, November 29). How The Chicago Bulls' Benny The Bull inspired a TikTok movement. Front Office Sports. https://frontofficesports.com/benny-the-bull-tiktok/
Nielsen Sports. (n.d.). Nielsen sports 2020 commercial trends. https://nielsensports.com/nielsen-sports-2020-commercial-trends/
Parker, K, & Igielnik, R. (2020). On the cusp of adulthood and facing an uncertain future: What we know about Gen Z so far. Pew Research Center. https://www.pewsocialtrends.org/essay/on-the-cusp-of-adulthood-and-facing-an-uncertain-future-what-we-know-about-gen-z-so-far/
Pegoraro, A. (2017). Sports fandom in the digital world. In P. M. Pederson (Ed.), Routledge Handbook of Sports Communication. Routledge.
Sehl, K. (2020, May 7). 20 important TikTok stats marketers need to know in 2020. Hootsuite. https://blog.hootsuite.com/tiktok-stats/#:~:text=TikTok%20has%20a%20reputation%20for,of%20the%20app's%20user%20base
Siguencia, L. O., Herman, D., Marzano, G., & Rodak, P. (2017). The role of social media in sports communication management: An analysis of Polish top league teams' strategy. Procedia Computer Science, 104, 73-80. https://doi.org/10.1016/j.procs.2017.01.074
Su, Y., Baker, B. J., Doyle, J. P., & Yan, M. (2020). Fan engagement in 15 seconds: Athletes' relationship marketing during a pandemic via TikTok. International Journal of Sport Communication, 13(3), 1-11. https://doi.org/10.1123/ijsc.2020-0238
Vrabel, J. (2017). Lions and tigers and bears (and zips and banana slugs and purple cows) — oh, my! NCAA Champion Magazine. http://www.ncaa.org/static/champion/mascots/
Wandel, T. L. (2017). Brand anthropomorphism: Collegiate mascots and social media. In R. Garg, R. Chhikara, T. K. Panda, & A. Kataria (Eds.), Driving customer appeal through the use of emotional branding. IGI Global.
Wang, Y., & Zhou, S. (2015). How do sports organizations use social media to build relationships? A content analysis of NBA clubs' Twitter use. International Journal of Sport Communication, 8(2), 133-148. https://doi.org/10.1123/ijsc.2014-0083
Wang, Y. (2020). Humor and camera view on mobile short-form video apps influence user experience and technology-adoption intent, an example of TikTok (DouYin). Computers in Human Behavior, 110, 1-9. https://doi.org/10.1016/j.chb.2020.106373
Waterloo, S. F., Baumgartner, S. E., Peter, J., & Valkenburg, P. M. (2018). Norms of online expressions of emotion: Comparing Facebook, Twitter, Instagram, and WhatsApp. New Media & Society, 20(5), 1813–1831. https://doi.org/10.1177/1461444817707349
Weiss, O. (1996). Media sports as a social substitution pseudosocial relations with sports figures. International Review for the Sociology of Sport, 31(1), 109-117. https://doi.org/10.1177/101269029603100106
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9. RIPPLE iOS Emulator For PC:-
I personally like this emulator the best. They are available for both the iPhone and IPad. This emulator goes beyond the normal usage of the emulator. You get many benefits of using the emulator. It is straightforward to understand and has a top-notch user interface.
One of the best uses of Ripple is that it can be used for testing the old and the newly developed applications together. You can also set it as a Google extension for daily uses and easy access. The software is in a beta stage, but it works well. There may be some bugs, but the developers are working on it.
Eve Hunt says
Yeah, that's what really makes writing GBA games a lot easier. Game Boy is a different beast altogether, where you can use C, but the generated code is terrible. If you want to make anything decent on a Game Boy you have to code in the assembly language.
I've only ever done GB programming – GBA looks really fun because of the ease of coding."


text:
Dès 1274, les premiers recteurs résidèrent à Pernes-les-Fontaines, ce ne fut qu'en 1320 qu'ils s'installèrent à Carpentras qui devint dès lors la capitale du Comtat Venaissin.

La liste repose principalement sur les travaux de Claude Faure, Étude sur l'administration et l'histoire du Comtat Venaissin du XIII au XV siècle (1229-1417) paru en 1909, qualifiée en 2007 de .

Recteurs du Comtat Venaissin
 Guillaume de Villaret (1274 – 1284/87)
 Henri de Giberiis (peut-être Henri de Genève) (1287 – 1289)
 Jean de Grallin (de Gralhino, dit Grillac par Cottier, probablement Jean de Grailly (janvier 1290)
 Philippe de Bernisson (Bernizon) (1290 – 1293)
 Jean de Grallin (de Gralhino, dit Grillac par Cottier, probablement Jean de Grailly (1295 - 1298)
 Biccio, Musciatto et Niccolo Franzesi (trois frères), chefs de la compagnie des Franzesi (1297 – 1299)
 Mathias de Théate, dit de Chiéti, évêque de Chiéti (1299 – 1302)
 Roger de Spinis (1302)
 Jean Arthenisii (1303)
 Guillaume de Mandagout, archevêque d'Embrun (1303 – 1310)

 Raymond Guilhem de Budos (1310 – 1317)
 Arnaud de Trian (1317 – 1334)
 Pierre Guilhem de Budos (1335 – 1341)
 Jean Arpadelle (1342 – 1343)
 Hugues de la Roche (1344 – 1353)
 Guillaume de Roffiac (1353 – 1362)
 Philippe de Cabassolle (1362 – 1370)
 Étienne Aubert (1370 – 1371)
 Aymar VI de Poitiers (1372 – 1376)
 Guillaume III Roger de Beaufort, vicomte de Turenne (1376 – 1379)
 Henri de Sévery (1379 – 1390)
 Odon de Villars (1390 – 1392)
 Pons de Langeac (1393 – 1394)
 Gaston de Moncada (1395 – 1397)
 Antoine de Luna (1397 – 1398)
 Jean de Alzenno (1399 – 1400)
 Pons de Langeac (1402)
 Antoine de Luna (1403 – 1408)
 Rodrigue de Luna (1408 – 1410)
 Jean de Poitiers (1410 – 1422)
 (Vacance du rectorat) (1423)

 Jacques de Complo (1424)

 Piero Cottini (1424 – 1431)

 Marco Condolmerio (1432)

 Onifre Francesco de San-Severino (1432 – 1433)

 Jean de Poitiers (1433)

 Roger de Foix de Castelbon (1433-1459)

 Angelo Geraldini (1459-1460)

 Constantin Heruli (1460-1472)

 Jean Bayle (1473)

 Frédéric de Saluces (1474)

 Édouard de Messey (1475)

 Renaud de Bourbon (1475-1476)

 Angelo Geraldini (1476-1478)

 Jean Rosa (1478-1479)

 Amalric de Vaison, évêque de Vaison (1479-1482)

 Jean Casaletti (1482)

 Rodolfo Bonicafio (1482)

 Guillaume Adhémar de Monteil (1483-1485)

 Constantin Heruli (1485-1490)

 Jean-André Grimaldi (1490 - 1495)

 Clément de la Rovère (1495 - 1502)

 Galeotto Franciotti (1502 - 1503)

 Louis de Rochechouart (1503 - 1505)

 François d'Estaing (1505 - 1509)

 Angelo Leonti (1510 - 1511)

 Jean de Montaigu (1511 - 1513)

 Pierre de Valetariis (1513 – 1514)

 François de Villeneuve (1514)

 Pierre de Brie (1515)

 Giscard de Corneillan (1516 – 1541)

 Paul Sadolet (1541 - 1547)

 Andrea Recuperati (1547 – 1553)

 Jacques Marie Sala (1553 – 1554)

 Antonio Vacca (1554 – 1555)

 Antonio Paolo Toscomi (1555)

 François de Castellane (1555 – 1560)

 Paul Sadolet (1560 – 1561)

 Laurent de Tarascon (1561 – 1565)

 Pierre Sabatier (1565 – 1566)

 François de Castellane (1566)

 Jean de Roquelaure (1566 – 1567)

 Paul Sadolet (1567 – 1572)

 Gaspard du Pont (1572)

 Jacques Sacrati (1572 – 1577)

 Dominique Grimaldi (1577 – 1584)

 Pompée Rocchi (1584 – 1586)

 François Argolici (1586 – 1587)

 Jacques Sacrati (1588 – 1593)

 Guillaume de Cheisolme (1593)

 Achille Gimnasi (1593 – 1594)

 Geronimo Leopardi (1594 – 1598)

 Horace Capponi (1598 – 1600)

 Jean de Tulle (1600 – 1605)

 Jacques Raccamador (1605 – 1607)

 Horace Capponi (1607 – 1609)

 Balthazare Gaddi (1609 – 1614)

 Cosme Bardi (1614 – 1615)

 Octavio Mancini (1615 – 1616)

 Cosme Bardi (1616 – 1621)

 Cesare Racagna (1621 – 1627)

 Antonio Brunacchi (1627)

 François de Suarès (1627)

 Persio Caraccio (1627 – 1630)

 Jean Baptiste Bongo (1630 – 1637)

 Jean Cosme Keermans (1637 – 1643)

 Guido Balde Gallo (1643 – 1644)

 Jean Cosme Keermans (1644 – 1652)

 Marius Buti (1652 – 1657)

 Cesare Salvani (1657 – 1664)

 Farulfe de Montemarte (1664 – 1672)

 Michele Antonio de Vibo (1672 – 1682)

 Jean Raszoni (1682 – 1689)

 Philippe Onofri (1689 – 1696)

 Scipio Zanelli (1696 – 1697)

 Flavio Barbarossa (1698 – 1702)

 François-Marie Abbati (1702 – 1707)

 Bernardino Giunigi (1707 – 1711)

 Charles-François Gallarini (1711)

 François-Marie Abbati (1711 – 1712)

 Alexandre François Codebo (1712 – 1716)

 Octavio Gasparini (1716 – 1733)

 Azzolini Cervini (1733 – 1738)

 Alessandro Guiccioli (1738 – 1745)

 Joseph-Dominique d'Inguimbert, dit dom Malachie (1745)

 Gaspard de Sainte-Croix (1745 – 1753)

 Tomasso Galli (1753 – 1755)

 Fortunato Savini (1755 – 1758)

 Charles Manzoni (1758 – 1768)

 Vacance du rectorat (1769 – 1773)

 Denis-François-Régis Valoris (1774 – 1776)

 Jules-César Zollio (1776 – 1785)

 Joseph-Vincent de Beni (1785 – 1787)

 Christiforo Pieracchi (1787 – 1790)

 Philippe Casoni, dernier recteur (1790 – 1791)

Le , en l'église Saint-Laurent de Bédarrides, fut décidé le rattachement du Comtat Venaissin à la France. Cet acte est considéré comme le premier exprimant le droit des peuples à disposer d'eux-mêmes.

Références

Voir aussi

Bibliographie
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 .
 .
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Articles connexes
 Carpentras
 Comtat Venaissin
 Légats pontificaux à Avignon
 Vice-légats pontificaux à Avignon

Papauté d'Avignon
Personnalité provençale du XIIIe siècle
Personnalité provençale du XIVe siècle
Personnalité provençale du XVe siècle
Personnalité provençale du XVIe siècle
Personnalité provençale du XVIIe siècle
Personnalité provençale du XVIIIe siècle


The Customer Coverage Analyst will use state-of-the-art analytical skills and techniques, both technical and intuitive, to analyze and model data and customer behaviors to influence coverage models. Analyze data to improve the effectiveness of sales coverage models for retention and penetration of targeted customers. This position is located at our Lake Forest IL headquarters, in the northern suburbs of Chicago.
Design data sets, run monthly data to support the functionally aligned coverage team.
Work cross functionally with other data driven departments to improve processes and data quality.
Prepare various deliverables and adhoc requests for business partners.
Work with large customer data sets to synthesize meaningful business insights identifying patterns, trends and translating those into actionable insights.
Build & deploy tools to execute against Grainger's defined coverage strategy.
Consolidate large amounts of data that can be visually represented to address a business problem.
Be a contributor to the continuous improvement process associated to customer data.
Bachelor's degree in Mathematics, Statistics, Physics or related fields preferred.
1-3 years of experience in a related field. Familiarity with analytics beyond the academic setting preferred (internships, consulting labs, etc.).
Strong strategic/innovative thinker grounded in analytics.
Modeling software: SAS or R - strong skills with one and at least some familiarity with the other preferred.
Solid coding skills and proficient with at least one programming language (C++, Java, Python etc).
Database management including advanced computer skills in Excel, Access, PowerPoint; experience with Tableau, SPSS, SQL, VBA or Teradata are preferred.
Strong information analysis and problem solving ability.
Strong oral and written communication skills; ability to translate information requests into practical outputs.
Demonstrates strong attention to detail, accuracy and thoroughness in work.
Able to collaborate and develop relationships across multiple functional areas.
Ability to operate in a complex, rapidly changing environment while adhering to tight schedules.
Ability to handle multiple projects simultaneously; demonstrated teamwork and collaboration skills.


Samsung's latest version of the Galaxy A7, better known as the Galaxy A7 2017 model, could be nearing an official launch soon as the phone has just been certified with the Wi-Fi Alliance. While this in itself does not guarantee that a launch is in the near future, it does point to possible nearby launch, especially when you consider that it has also been certified by the FCC which happened back on December 2nd. In addition to the FCC certification and the newly discovered Wi-Fi certification, the Galaxy A7 2017 was also reportedly shown off at a small event last week where it was discussed and put on display next to the Galaxy A3 2017 and the Galaxy A5 2017 devices.
Last week's event also revealed a few features of the upcoming phones, although these still can't be verified as official since the phone has not yet been announced. That being said, what is rumored to be on the table is something that was likely expected - the IP68 certification making these devices dust and water resistant. There is unfortunately no new information that is really useful on the Wi-Fi certification document in regards to features for the Galaxy A7 2017, so consumers are left with the rumored hardware details for now, of course, that could all soon change if Samsung is getting ready to show off these new devices sometime soon, which would likely happen at CES as that's the next trade show, although Samsung could also choose to simply announce the phones outside of an event.
As far as what specs are rumored to be on offer so far beyond the IP68 certification that was mentioned above, the Samsung Galaxy A7 2017 is said to have 16-megapixel main and secondary cameras, which means Samsung is rumored to be fitting the same sensor on both the front and on the back of the device. It's also rumored to come with 3GB of RAM and 32GB of internal storage space that's expandable by a microSD card, and come with Android 6.0.1 Marshmallow on board for the software, while also supporting USB Type-C for the charging and data transfer port. All in all, not a huge deviation from the previous Galaxy A7 device, but potentially a few pieces of newer hardware.


QuickBooks software is a robust creation, manufactured helping businesses to create a higher-value proposition for customers. This value-adding software has witnessed immense growth owing to differentiation, competitive advantage and customer value that it offers to its clientele. There is no denying the fact that QuickBooks makes the business a real breeze. It allows organizations from all walk of life to efficaciously maintain and manage their finances without negotiating on security, performance, and accuracy. If reports are to be trusted a horde of organizations are shifting gears to this accounting and payroll software to manage their finances in a seamless manner.
However, like other software applications, QuickBooks may also generate a few errors that can hinder smooth business functioning. One such error is QuickBooks Error -6135,-1005. Apparently, error -6135,-1005 happens when a user tries to access QuickBooks company data file in the old or previous version of the QuickBooks application, which was updated in the latest edition of QuickBooks. To put it simply, the issue implies that files may have got jammed somewhere or still open on some system. Also, it suggests that the treatment of the file has completely failed.
A professional QuickBooks service provider employs a learned team of certified professionals who are available 24*7 to help users with such pestering QuickBooks issue.
One of the possible reasons for this irking error can be hosting for the file has been lost, if the user has used the file in multi-user mode on multiple computers with multiple users. Going forward, this error can also arise if the user tries to open a company file of QuickBooks in the older QuickBooks edition which was upgraded to the advanced QuickBooks edition.
Now, let's move to the resolution of QuickBooks error -6135 -1005?
It might be possible that these solutions may resolve your issue or you may need to try all of the suggestions. In case, if you are still juggling with QuickBooks error, connect with our QuickBooks customer support team to seek immediate resolution for your problems. This failure can be fixed by the experts of the QuickBooks tech Support team over the call, or through email support. You can seek support from wherever you are by connecting with our ardent professionals from the comfort of your home/office.