text:
Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level
Josephine A Wright, Patrick C McHugh, Siyi Pan, Adam Cunningham, David R Brown
Alpha-synuclein is a cytosolic protein associated with a range of diseases including Parkinson's disease. In these diseases alpha-synuclein aggregates and this is believed to play a causative role in disease progression. Alpha-synuclein aggregation has been suggested to be caused by increased expression levels and has also been suggested to be countered by increased beta-synuclein expression. In this regard, strategies to counter-regulate the expression of the synucleins by increasing beta-synuclein expression relative to alpha-synuclein may be beneficial in preventing disease progression. We therefore studied the regulation of alpha-synuclein to try to identify pathways that might counter-regulate the synucleins. We identified members of the ZSCAN family of transcription factors as specific repressors of alpha-synuclein. In particular ZSCAN21 was found to both repress alpha-synuclein and increase beta-synuclein expression. These findings support the notion that a single pathway in the cell can counter-regulate the expression of the synucleins. Support for this came from experiments that showed that ZSCAN21 expression decreases alpha-synuclein aggregation in the cells.
Molecular and Cellular Neurosciences
https://doi.org/10.1016/j.mcn.2013.09.002
10.1016/j.mcn.2013.09.002Licence: Other
Dive into the research topics of 'Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level'. Together they form a unique fingerprint.
beta-Synuclein Medicine & Life Sciences 100%
alpha-Synuclein Medicine & Life Sciences 70%
Synucleins Medicine & Life Sciences 33%
Disease Progression Medicine & Life Sciences 11%
Cell Aggregation Medicine & Life Sciences 9%
Parkinson Disease Medicine & Life Sciences 6%
Transcription Factors Medicine & Life Sciences 5%
Proteins Medicine & Life Sciences 2%
Wright, J. A., McHugh, P. C., Pan, S., Cunningham, A., & Brown, D. R. (2013). Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level. Molecular and Cellular Neurosciences, 57, 33-41. https://doi.org/10.1016/j.mcn.2013.09.002
Wright, Josephine A ; McHugh, Patrick C ; Pan, Siyi et al. / Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level. In: Molecular and Cellular Neurosciences. 2013 ; Vol. 57. pp. 33-41.
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abstract = "Alpha-synuclein is a cytosolic protein associated with a range of diseases including Parkinson's disease. In these diseases alpha-synuclein aggregates and this is believed to play a causative role in disease progression. Alpha-synuclein aggregation has been suggested to be caused by increased expression levels and has also been suggested to be countered by increased beta-synuclein expression. In this regard, strategies to counter-regulate the expression of the synucleins by increasing beta-synuclein expression relative to alpha-synuclein may be beneficial in preventing disease progression. We therefore studied the regulation of alpha-synuclein to try to identify pathways that might counter-regulate the synucleins. We identified members of the ZSCAN family of transcription factors as specific repressors of alpha-synuclein. In particular ZSCAN21 was found to both repress alpha-synuclein and increase beta-synuclein expression. These findings support the notion that a single pathway in the cell can counter-regulate the expression of the synucleins. Support for this came from experiments that showed that ZSCAN21 expression decreases alpha-synuclein aggregation in the cells.",
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Wright, JA, McHugh, PC, Pan, S, Cunningham, A & Brown, DR 2013, 'Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level', Molecular and Cellular Neurosciences, vol. 57, pp. 33-41. https://doi.org/10.1016/j.mcn.2013.09.002
Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level. / Wright, Josephine A; McHugh, Patrick C; Pan, Siyi et al.
In: Molecular and Cellular Neurosciences, Vol. 57, 11.2013, p. 33-41.
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AU - McHugh, Patrick C
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N1 - © 2013.
N2 - Alpha-synuclein is a cytosolic protein associated with a range of diseases including Parkinson's disease. In these diseases alpha-synuclein aggregates and this is believed to play a causative role in disease progression. Alpha-synuclein aggregation has been suggested to be caused by increased expression levels and has also been suggested to be countered by increased beta-synuclein expression. In this regard, strategies to counter-regulate the expression of the synucleins by increasing beta-synuclein expression relative to alpha-synuclein may be beneficial in preventing disease progression. We therefore studied the regulation of alpha-synuclein to try to identify pathways that might counter-regulate the synucleins. We identified members of the ZSCAN family of transcription factors as specific repressors of alpha-synuclein. In particular ZSCAN21 was found to both repress alpha-synuclein and increase beta-synuclein expression. These findings support the notion that a single pathway in the cell can counter-regulate the expression of the synucleins. Support for this came from experiments that showed that ZSCAN21 expression decreases alpha-synuclein aggregation in the cells.
AB - Alpha-synuclein is a cytosolic protein associated with a range of diseases including Parkinson's disease. In these diseases alpha-synuclein aggregates and this is believed to play a causative role in disease progression. Alpha-synuclein aggregation has been suggested to be caused by increased expression levels and has also been suggested to be countered by increased beta-synuclein expression. In this regard, strategies to counter-regulate the expression of the synucleins by increasing beta-synuclein expression relative to alpha-synuclein may be beneficial in preventing disease progression. We therefore studied the regulation of alpha-synuclein to try to identify pathways that might counter-regulate the synucleins. We identified members of the ZSCAN family of transcription factors as specific repressors of alpha-synuclein. In particular ZSCAN21 was found to both repress alpha-synuclein and increase beta-synuclein expression. These findings support the notion that a single pathway in the cell can counter-regulate the expression of the synucleins. Support for this came from experiments that showed that ZSCAN21 expression decreases alpha-synuclein aggregation in the cells.
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Wright JA, McHugh PC, Pan S, Cunningham A, Brown DR. Counter-regulation of alpha- and beta-synuclein expression at the transcriptional level. Molecular and Cellular Neurosciences. 2013 Nov;57:33-41. https://doi.org/10.1016/j.mcn.2013.09.002


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Google One Gets Introduced for Expanded Storage and Comes With Extra Benefits
Google introduced Google One yesterday, May 14, which is a solution for expanded storage and brings extra benefits for the users. As a part of this procedure, all the paid plans for the users of Google Drive storage will be upgraded to Google One in the coming months.
The new changes do not affect the G Suite business customers, and neither do they alter any interface for storing and sharing files via Drive.
To start with, users of storage paid plans will now have access to all the space they require in Drive, Gmail, and Google Photos. It comes with options ranging from 100 GB to 30 TB.
Secondly, Google One will be covering a lot of other Google products too'. It gives you one-tap access to the experts regarding the company's products and services. This further brings 'access to extras' from certain of its products, like offers on select hotels that appear on Search or credits on Google Play. The announcement blog states that the tech leader will come up with more benefits over time.
Last but not least, Google One lets you add up to five family members into your selected storage plan. Therefore, you will get to pay for the storage that's shared with your family under one bill. Every of your added family members will have the same benefits from Google One as you. By putting this benefit on the table, Google is addressing its frequently received requests regarding storage plans to be shareable within the family.
All users with a paid Drive storage plan will be automatically upgraded to Google One in the upcoming months. The rollout will begin in the U.S. and will eventually expand globally. Users will receive an email confirming the upgrade, and it will lead you to manage the storage plan and the benefits.
Google says that the works on Google One are still going on and will surface later this year. Stay with us to not miss out on the update.

redpajama_set_name: RedPajamaCommonCrawl


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Sony will produce movies based on the memoirs of Father Amorth
May 17, 2018 Ganiveta News 0
"St. Augustine and the Devil" c.1471 by Michael Pacher
Sagas like The Conjuring, Insidious, all their spin-offs and a little before the Paranormal Activity set of films are proving that the supernatural is a big hype nowadays, and a very profitable theme for not so expensive big grossing movies. That's why it is a common thing to happen that big studios are moving towards that direction, securing potential stories and characters for their own purposes. Now it's the time for Sony Pictures, who has purchased the exploitation rights of the late Father Amorth memoirs in order to create their own saga of exorcism-themed films.
Reverend Gabriele Amorth (1925 –2016) was an Italian Roman Catholic Priest and an exorcist of the Diocese of Rome who performed tens of thousands of exorcisms over his half a dozen plus decades as a Catholic Priest. He never served as "the Vatican's chief exorcist" or any similar role, despite popular media headlines. Although his name doesn't ring a bell to the big audience, in the last couple of years he has been quite notorious for being the center of the documentary The Devil and Father Amorth (2017), directed by William Friedkin. In it, the veteran filmmaker follows Father Amorth in his quest of performing a real exorcism on an Italian woman. The movie questions science and supernatural, psychology and religious rites, in order to diagnose and eventually cure something so mysterious and threatening as a demonic possession.
In his long ride as a Vatican exorcist, Father Amorth has written a good bunch of memoirs that have been published. Books like An Exorcist Tells His Story (1999), An Exorcist: More Stories (2002) and An Exorcist Explains the Demonic: The Antics of Satan and His Army of Fallen Angels (2016), only to name a few, could stand as the most notorious ones. Now, his stories with hundreds of documented cases of possible demonical possessions can be the object of a series of films developed by Sony.
What are their plans? Will they start a franchise where a fictitious Father Amorth will fight against Evil? Or perhaps will they set up a bunch of anonymous characters in situations based on the experiences in the books? That is yet to know. But what seems clear is that now that William Friedkin's The Exorcist (1973), undisputedly the best movie in this genre, is turning 45 years old, the fighters against Evil are going to be quite busy on the silver screen.
William Friedkin's real exorcism documentary opens in theatres in the U.S. April 20 The Devil and Father Amorth (2017) Real exorcism documentary "The Devil and Father Amorth" has the trailer out Sony has found a director for the Robotech movie
An Exorcist Explains the Demonic
An Exorcist Explains the Demonic: The Antics of Satan and His Army of Fallen Angels
An Exorcist Tells His Story
An Exorcist: More Stories
Diocese of Rome
exorcism-themed films
Father Amorth
Reverend Gabriele Amorth
The Antics of Satan and His Army of Fallen Angels
The Devil and Father Amorth


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Дыбравино () — село в Болгарии. Находится в Варненской области, входит в общину Аврен. Население составляет 1 453 человека.

Политическая ситуация
В местном кметстве Дыбравино, в состав которого входит Дыбравино, должность кмета (старосты) исполняет Атанас Иванов Атанасов (Граждане за европейское развитие Болгарии (ГЕРБ)) по результатам выборов.

Кмет (мэр) общины Аврен — Красимир Христов Тодоров (коалиция в составе 2 партий: Национальное движение «Симеон Второй» (НДСВ), Болгарская социал-демократия (БСД)) по результатам выборов.

Ссылки
 Статистика населения

Сёла Варненской области

redpajama_set_name: RedPajamaWikipedia


I graduated from Ryerson University in April 2017 and have been working professionally in child care since.
Energetic, fun, out-of-the-box thinker. My professional experience working in child care has allowed me to plan various activities for toddlers to children who are 12 years old. I take the time to get to know the children I work with and shape my time with them around their own interests.


This topic is 401 days old which is more than the 365 day threshold we allow for new replies. Please post a new topic.
as I found out, the time on server is the referencing time. if you want to check for example when really player fired his gun we have to do some calculation based on server time and rtt or user ping. I this right? do we have exact rtt for every message? is this all we have to do for time synchronization in real-time games?
You can never guarantee perfect synchronisation, so you can never be 100% sure of when a client performed a certain action. All you can do is decrease the degree of error. If you are continually measuring and correcting the RTT then you can be reasonably confident about the time that the client performed the action - unless their network latency changed significantly since your last measurement, which does sometimes happen organically, and also sometimes happens artificially when it might benefit the player.
You can choose to let clients send the time of their action, and compare that to your estimate based on RTT. The server could then choose to accept the client's reported time providing it doesn't differ too much from your calculation - this will give you slightly more accurate timings for the players that aren't cheating, but gives players a small opportunity to cheat by manipulating that value when it suits them.
There is no "the time it REALLY happened."
The best you can do is agree on an order of events -- "X happened before Y."
And even that is hard when two different players talk to the same server.
The way this is typically solved is that simulation is done in time steps, typically of a fixed size. The server and players then use the same time step numbers, and any action sent is tagged as "this action happened at time step X."
You can do this with variable time step size (Unreal Engine doesn't have fixed time step, for example,) and then you'd simply send the timestamp instead of the time step number, for each event.
This also lets each side bunch events from a number of simulation steps into a single network packet. For example, you may simulate 144 times per second, but only send network packets 40 times per second; each packet will then contain the events for 3 or 4 time steps. Bunching transmissions up like this does add some additional latency to the networking, but as you typically need to work with connections with high latency anyway, it's not that bad. Sending packets 40 times a second means you delay any particular event at most 25 milliseconds; players in Massachusetts connecting to a server in Atlanta will typically see more latency than that just in transmission time, anyway.
If you have the clients send their own timestamp, does that mean you would also do some server rewind and replay?
Or would you run the server's timeline behind the clients so that incoming timestamps have usually not occurred on the server's timeline yet?
Or maybe another way of saying that is having the clients timestamp their actions slightly in the future?
what about using ntp for synchronization? does it work for real-time games?
That solves the wrong problem. The problem is not that one client might be two milliseconds ahead of some other client. The problem is that there is 100 milliseconds latency from the client to the server, and then another 100 milliseconds of latency from the server to the other client. Having the server send "this is my current clock at game tick number X" to each client in its packets is perfectly good enough to derive a good clock on the clients; any improvement on that is not going to lead to improvements in gameplay.


In going to get keyboard responses out of the log file, I'm noticing the Resp and Name values do not match -- Resp is one number higher than Name (e.g., 6 vs 5, 2 vs 1). Given that they're numeric responses, I assume they should be the same. Is "Name" the subject's actual response?
I've been using the XP version from the end of last year, and found this identical problem: inconsistently, numerical values in the Resp column on the last stimulus of each trial will be one less than the Name column. Two questions: which is the actual response I should be extracting, and should I be concerned that this is inconsistently occurring? It only seems to happen for around a third of the time.
Just re-read the other problems and realised mine is the opposite way around - could this be due to the counter-measure employed in fixing the original bug? Mine has Resp one LOWER than Name.
Hmm. What version are you running--i.e., 200x.x.x? If it's any release of v2008, would you please post a sample input file and it's data so I can see what you are getting?
It's version 2008.1.0.11, with the input file 'sampleinput' attached and 'sample2_log' output. On some files, it seems to happen every time, but not on this one. With cell refs I&J 14, 18, 22, 26 etc (wherever the last trial falls), Name=Resp+1. But if you look at I30, it is the same as J30. The same happens on row 254. Perhaps it only happens when Name=1 that Resp is also 1. It is only ever with the last stimulus of each trial though, as the responses to the second stimulus of each trial (stimuli 2 and 4 are identical) are accurately recorded through my DirectRT button box in both Name and Resp columns.
I'm thinking that 'Name' is the correct column?
Last edited by jarvis24; 03-31-2009 at 10:19 PM.
This is odd indeed. Safe to assume you are using v2008? It does seem that in your case response is always one less--unless name = 1. Does this replicate with your keyboard (i.e., if you do not use the button box)? Also, are you using any grid functions (mouse cursor, light gun, touch screen)?
Could you run the attached, simplified, input file and see if the results are consistent when using your keyboard? If so, could you please attach the log file?
Last edited by jarvis24; 03-31-2009 at 10:20 PM.
We are trying to record multiple responses on a single trial where participants first make five keypress responses and then five where they click on text-cursor defined areas of the screen. For the mouse click text-cursor responses, the "Name" of each response is being recorded correctly, but sometimes the "Resp" column is incorrect. This error has only been noted on the last reponse, but does not always occur on this last response. Attached are some examples of the log files. In 18_log, response name 5 is incorrectly recorded in the "Resp" column as 4 when this response was the last to be given, but in 22_log, response 5 is correctly recorded in the "Resp" column when it was the first to be given. In 17_log, all responses were correctly recorded in the "Resp" column, including the last one. Any solution? Thanks!
Does the same pattern emerge if you use the corresponding keystrokes instead of mouse clicks? If so, can you attach or send me a copy of your input file so I can try running it here?
Last edited by jarvis24; 03-31-2009 at 10:22 PM.
Yes, the same problem occurs with keypad input. Attached is the zipped file.
We are having the exact same problem. Has this issue been resolved? Without a solution, it makes the data unusable.
Try running the simplified "sampleinput2.csv" input file above. If it works fine but yours does not, then can you tell me if you are using a grid based system (e.g., cursor, touch screen, light gun) at all in your session and what version you are running, i.e., 200x.x.x?
Last edited by jarvis24; 06-25-2009 at 12:26 PM.


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Home > US Sports > NFL > Peyton Manning Is Now The NFL's All-Time Leader In Career Touchdown Passes
Peyton Manning Is Now The NFL's All-Time Leader In Career Touchdown Passes
by Code Jones - 20th October 2014 30th June 2018 0
The Denver Broncos quarterback Peyton Manning has tonight broken the record for the most touchdown passes in NFL history, he threw his 509th in the Broncos victory over San Francisco 49ers. It was his third of the game as his eight yard pass was caught by Demaryius Thomas and that took him past the record previously held by Brett Favre.
He reached the record in his 246th game, 56 fewer games than Favre. Manning went into the game with 506 and needed just four drives to break the record.
He added another, his fourth touchdown pass of the game which was again caught by Demaryius Thomas. The Broncos dominated the match winning 42-17 to improve their record to (5-1) for the season and consolidate their position in first in the AFC West.
Peyton Manning went on to complete 22 of 26 passes and finished with 318 passing yards as the Broncos blew out 49ers
Peyton Manning now holds the record for the most touchdown passes in NFL history, he moved two ahead of Brett Favre. They are the only two players to have thrown more than 500 touchdown passes.
"It's quite an honor. I do have great appreciation for the quarterbacks that have played this game throughout the years. So I'm honored just to play the position. It's very humbling," Manning said of the record after the game.
"I think Brett has always known he's one of my favorite players. He played the position with so much passion and just great toughness and great productivity as a quarterback. So I just want to tell him thanks, and I'm honored to sort of join this club with him."
Manning reached the milestone in just his 246th regular-season game – Favre needed 302.
Favre was quick to congratulate Manning after the game when he tweeted:
Well deserved Peyton. Congratulations on breaking my record. #Onto600 http://t.co/MEeffAlmeP
— Brett Favre (@Favre4Official) October 20, 2014
Broncos fans erupted when Manning connected with Thomas for a touchdown that with the extra point put the Broncos up 21-3 with 3:09 remaining in the second quarter.
Favre said he enjoys watching Manning go to work on the TV at home.
"He's a throwback, a pocket passer, in a mobile quarterback league," Favre said.
"Peyton's one of the last guys to play the way he does. And at 38, he's still the best at what he does."
Denver coach John Fox paid tribute to the lynchpin of his team.
"It was pretty special to witness such an accomplishment," Fox said.
"This was probably our most complete game to date, both offensively, defensively, as well as the kicking game."
Tagged 49ers Brett Favre Denver Broncos NFL Peyton Manning
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Shirley Jackson's Haunting Interiors
Cited as a major influence for writers like Stephen King and Neil Gaiman, it is impossible to discuss horror without mentioning Shirley Jackson. Especially this time of year. The New Yorker published an essay, "The Haunted Mind of Shirley Jackson" this week, and today we take a look at her incredible ability to write from the perspective of unreliable narrators. Enjoy, "Shirley Jackson's Haunting Interiors" below.
October is our favorite month of the year. As the air cools, and the leaves begin to fall, we welcome the extra time spent indoors, warm cups of tea, and the increase in shadows. We focus every October on content that is dark, strange, and a little scary, and it's a treat to think about writers who occupy this space in fiction. Every year I circle back to one of my favorites: the inimitable Shirley Jackson.
Jackson's most famous short story is perhaps "The Lottery." It debuted in The New Yorker in 1948 and remains one of the magazine's most divisive pieces. After it published, hundreds of people cancelled their subscriptions. The magazine was flooded with hate mail. That is to say, the piece hit a nerve.
And indeed "The Lottery" is terrifying. Without giving the story away, over the course of a few pages Jackson takes readers to a world inhabited by characters with unexpected emotional responses, through twists and turns of pathology, and by the story's dark conclusion—as strange as it may be—there is a terrible and haunting familiarity.
When I think about influential writers and why their work is effective, each of them has talents that seem magical. But Shirley Jackson is a special kind of sorcerer. She evokes the strange in small steps. If you examine her work line-by-line or word-by-word you find a simple writer. There isn't anything strange or oversized about her language, nor is her sentence structure elaborate or unique. Instead readers discover, as they do in "The Lottery," that suddenly they are standing in a dark wood. What had been a walk on a well-established trail is now a sinister and eerie forest. Almost always in a Shirley Jackson story you ask yourself: how did I get here?
Two of my favorite Shirley Jackson novels are The Haunting of Hill House and We Have Always Lived in The Castle. In both, readers experience terror as the result of a cumulative roll—single, logical steps that lead, somehow, into deep and uninviting territory.
In The Haunting of Hill House, four guests are invited to spend a summer at Hill House in hopes of providing scientific evidence for paranormal activity. One of the main characters is Eleanor, who comes to the mansion eager to experience a bigger world. Over the course of the narrative, she slips slowly out of reality and embodies the paranormal psychology of the house.
Suddenly, without reason, laughter trembled inside Eleanor; she wanted to run to the head of the table and hug the doctor, she wanted to reel, chanting, across the stretches of the lawn, she wanted to sing and to shout and to fling her arms and move in great emphatic, possessing circles around the rooms of Hill House; I am here, I am here, she thought.
In Shirley Jackson's essay "Garlic in Fiction," she discusses the issue of leading Eleanor (and the reader) through this slow slip of worlds. Jackson writes:
…there had to be a transition for the reader, from the sensible environment of the city to the somewhat less believable atmosphere of the haunted house, and the preparation had to be made carefully, in Eleanor's mind and in the reader's, for the introduction of the horrors to come later, and Eleanor's reactions. The reader had to be persuaded to identify sufficiently with Eleanor so that when later he encounters with her the various manifestations in the haunted house he will be willing to suspend disbelief and go along with Eleanor, because she has become thoroughly believable.
Jackson ends this graph with the note: "This was hard."
Indeed. In my opinion, Jackson is talking about the difficulty of interiority—the idea of giving readers access to a character's thoughts and feelings. At The Masters Review, we talk a lot about interiority because we see a great many stories that lack access to their characters' thoughts. It is a difficult thing to do well, and it speaks to the challenge of understanding your work. But great writers, even those with formally distant characters (think Raymond Carver), execute a full understanding of their characters' emotions. The result is satisfying. Fiction with good interiority is powerful and effective. They are the stories you remember. They are the narratives that feel the most real.
What makes Jackson's attention to interiority so special—and cements her as one of the best executors of this technique—is her success in making the unreal believable. And what a challenge! To develop the kind of interiority that allows the strange, the paranormal, and the horrible, to feel like a logical extension of your character. Shirley Jackson's haunting interiors feel like nothing more than the next step along the trail. The result is magical.
Take a look at any of Jackson's work and this skill is evident. In another of her celebrated novels, We Have Always Lived in The Castle, Jackson writes from the perspective of Merricat, a young girl and one of the few survivors of a mass cyanide poisoning that killed her family. It soon becomes evident that Merricat—engaging, smart, and highly self-aware—is the likely perpetrator of the poison.
I believe many writers would choose to write the novel from an outsider's perspective. But there is deep satisfaction for the reader in experiencing the mysterious psychology of Merricat—and the mystery of the poisonings themselves—unravel from her perspective. It tackles the events of the story on a level that demands effective interiority. And rightfully so: it is nearly impossible to write on a believable level from the perspective of someone who is murderous, going insane, or possibly possessed by the paranormal in a way that is believable.
Joyce Carol Oates writes of We Have Always Lived in The Castle: "…that masterwork of unreliable narration in which we are intimate witnesses to a naively repressed young woman." When Joyce Carol Oates mentions readers being "intimate witnesses," she is talking about Merricat's haunting interior, how effectively Jackson applies it, and the kind of access we have to the narrator's psychology. Over the course of the narrative readers see through Merricat's eyes how she understands the act of poisoning her family, and how darkly removed she is from seeing it as an act of wickedness.
Shirley Jackson excels at the dark and the strange, but I find her unique (aside from a few examples like Charlotte Perkins Gilman's famous, "The Yellow Wallpaper" ) in her ability to write fiction that inhabits the perspective of an unreliable character with such skill. She has taken one of the most difficult aspects of writing a memorable and effective narrative and doubled down by applying it to unreliable psychology. She is a true master of interiority.
How does a writer come to such skill? I cannot comment on the inner workings of Shirley Jackson's mind, but I do have a playful theory born from her essay "Good Old House." In the essay, Jackson explains in a frank and straightforward manner, her experience living in a house haunted by ghosts:
Still another troubling thing was the way small articles disappeared. I realized that in a large house with small children, things are always disappearing anyway, but this was different; it was as though there were pockets of time in the house into which things dropped for a little while and then came back…. Once, a little round rug disappeared for almost a week from the study, as though it had been absorbed into the floor, and reappeared after a while looking the same as ever… Once, buttons appeared, newly sewn onto my son's jacket, and another time my daughter's stuffed lamb had a blue ribbon removed and pink one substituted. A day or so later the blue ribbon was back, washed and ironed.
Small things still disappear, of course, and for a while Joanne spoke occasionally of a faraway voice that sang to her at night. Once I went into the kitchen and found a still-warm pumpkin pie on the table, covered with a clean cloth; we had it for dinner and praised it in voices that we hoped would carry throughout the old house.
Perhaps Jackson writes the unreal so well because she has a foot in both worlds. One with ghosts, ghouls, and haunted houses, and one in the world most of us live in: a place that senses the presence of the paranormal, but only experiences flickers of it. Either way, her stories remain icons of the American horror genre and are beloved because of her commitment to understanding characters, even when those that inhabit the unreal.
by Kim Winternheimer


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Iowa crane plant closing, 175 losing jobs
WAVERLY, Ia. — About 175 workers are losing their jobs with the closure of the Terex crane plant in the northeast Iowa city of Waverly.
The company announced Tuesday that it is moving production of cranes and boom trucks to its Oklahoma City plant, where it has made multimillion-dollar upgrades to handle the new load.
About 100 Iowa workers lost their jobs immediately. The remaining 75 jobs will be phased out. Terex says it will keep its accounting offices in Waverly, which employs 100 people.
Waverly City Administrator James Bronner says state and local economic development resources will aid the displaced workers and their families. The Iowa Economic Development Authority and Iowa Workforce Development have been notified of the closure.
Bronner told the Waterloo-Cedar Falls Courier that he was informed by longtime Terex executive Dave Stevenson about the closure. Bronner said he asked if there was anything the city could have done to prevent the situation.
"He said, 'No, not really.' It was the oil prices and the construction industry being down. He said the decision was made at the corporate offices," according to Bronner.
The company says the Waverly operation was established in 1941 by brothers Vern and Wilbur Schield. The operation became part of Terex Corp. in 1987.
Terex Corporate said in a statement that "moving Waverly product lines to our Oklahoma City location is consistent with our continuing strategy to win the market place by aligning our costs with market demands."
KCRG-TV reports that the company cited costs as the reason to consolidate its operations in Oklahoma City and that it is centrally located to optimize the transportation of raw materials and finished products.


text:
Leonpol (biał. Лявонпаль, Lawonpal) – wieś na Białorusi, w obwodzie witebskim, w rejonie miorskim, nad rzeką Dźwiną.

Siedziba parafii prawosławnej pw. Świętej Trójcy.

Dawne miasteczko województwa połockiego I Rzeczypospolitej, do 1945 miasteczko w Polsce, w województwie wileńskim, w powiecie dziśnieńskim do 1925, w pow. brasławskim do 1939, siedziba gminy Leonpol.

Historia
W 1745 roku pisarz wielki litewski Mikołaj Tadeusz Łopaciński nabył majątek zwany "Czuryłowicze" lub "Lilki" od Kleczkowskich i zmienił jego nazwę na Leonpol na cześć swojego ojca Leona. W latach 1768–1769 M. Łopaciński wybudował tutaj niewielki pałac w stylu późnego baroku. W 1772 roku zbudowano kościół wraz z dzwonnicą. Własność Łopacińskich z linii wojewódzkiej: Mikołaja Tadeusza do 1778 roku, z odnogi szarkowskiej – Jana Nikodema aż do sprzedaży w 1802 roku, z odnogi saryjskiej – Tomasza Ignacego do 1817 roku, Józefa Adama do 1835 roku, Ignacego Dominika do 1882 roku, Stanisława Jana, a następnie Euzebiusza Mariana do 1939 roku. W latach 1842–45 majątek był zarekwirowany przez władze carskie, w związku ze sprzeciwem I. Łopacińskiego, wyrażonym wobec przymusowego nawracania jego unickich poddanych na prawosławie.

W wyniku II rozbioru Polski miejscowość została przyłączona do Rosji w składzie powiatu dziśnieńskiego guberni mińskiej (od 1842 roku w guberni wileńskiej). W I poł. XIX wieku działała tkalnia płótna, obrusów i serwet z miejscowego lnu, zamknięta w 1840 roku. W 1863 roku wojska rosyjskie spaliły pałac, a główna siedziba rodu została przeniesiona do Sarii. Pałac został odbudowany dopiero w latach 1905–06 przez St. Łopacińskiego. W 1866 roku było 26 domów i 109 mieszkańców (69 Żydów, 27 prawosławnych i 15 rzym. kat.).

W 1919 roku spłonął pałac, który został przekazany przez Euzebiusza Łopacińskiego na potrzeby kościoła katolickiego, po 1925 roku odbudowany i przebudowany jego kosztem przez architekta Jana Borowskiego. W 1921 roku w miasteczku były 72 domy i 382 mieszkańów (172 prawosł., 138 Żydów i 66 rzym. kat.), a w folwarku 7 domów i 54 mieszk. (35 rzym. kat. i 19 prawosł.). W 1931 roku w miasteczku było 84 domów i 482 mieszk., a w folwarku 5 domów i 48 mieszkańców.

W okresie międzywojennym umiejscowiona była tu kompania graniczna KOP "Leonpol" oraz strażnica KOP "Leonpol".

Po II wojnie światowej zamknięto cerkiew (dawny kościół), a w pałacu mieściły się mleczarnia, technikum rolnicze i szkoła specjalna.

Obecnie (w niepodległej Białorusi) cerkiew pełni funkcje kultowe.

Zabytki
 Pałac w stylu późnego baroku (1768-1769), który zachował się do naszych czasów. Nie zachowały się park francuski na tarasach oraz brama wjazdowa w osi pałacu
 Cerkiew Świętej Trójcy (1774–1782), d. greckokatolicka, obecnie prawosławna, zbudowana przez Mikołaja Łopacińskiego, świątynia parafialna
 Kolumna ku czci Konstytucji 3 Maja (1791) ufundowana przez Jana Nikodema Łopacińskiego w końcu XVIII w.

Galeria

Linki zewnętrzne

 Leonpol. Zespół dworsko-parkowy Łopacińskich

Przypisy

Dawne miasta w Polsce
Leonpol
Łopacińscy herbu Lubicz
Rejon miorski
Garnizony KOP
Dawne miasta na Białorusi
Wsie w rejonie miorskim


text:
Baseball: Galena the favorite as Regional begins
Jim Krajewski
jkrajewski@rgj.com
After a roller-coaster of a season, in which one team emerged as the clear favorite, it's playoff time.
Now Galena just hopes to avoid the fate suffered by Damonte Ranch last season. Galena rolled to a 20-2 regular season record to claim the title. Last year, Damonte did the same thing, going 19-3, then lost its first two games at Regionals.
"That speaks to the depth of our league," Galena coach Dave Kulikowski said. "I think it's a matter of (Damonte) did anything wrong. Everybody else is doing things the right way to handle that situation. We just want to play our best baseball and focus on throwing strikes, playing good defense and timely hitting."
No. 1 seed Galena will host No 8 seed Reed at 4 p.m. Tuesday. Other games Tuesday, all at 4 p.m., are: No. 5 Spanish Springs at No. 4 Bishop Manogue; No. 7 McQueen at No. 2 Carson and No. 6 Damonte ranch at No. 3 Reno.
Galena's only league losses were to Douglas, which did not qualify for the playoffs, and to Reno.
Reed's ace pitcher, senior Austin Beard is back and expected to start on the mound today. He battled a hematoma in his leg during the season and did not pitch much after the midway point. But he is back to near full health.
Reed was hurt by several errors in a loss to Spanish Springs on Friday.
Reed coach John Phenix said the Raiders will need to cut down on errors in Regionals.
"We can't make mistakes against them, the pitcher's got to get ahead," Phenix said of the Grizzlies. "They're a good-hitting team. They're not going to strike out a lot. They're going to put the ball in play. We've got slow them down. It would be nice to jump out early and put some pressure on them."
Manogue is on a roll heading into playoffs after beating Reno twice last week. Spanish Springs swept Manogue in mid-March.
"It all comes down to defense for us. Defense, and timely hitting," Spanish Springs coach Ben Hoffman said. "We've got some things going right now and hopefully we keep it going."
He said Manogue has improved significantly since March.
"It's a long time ago. Looking at their lineup now, it looks like it's a little different than it was early in the year," Hoffman said. "It's going to be difficult for sure. It's never easy when you get to this point.
Ryan Anderson, the Cougars 6-foot-5 lefty, will get the start on the hill.
"He's pitched well against them. He's pitched well against a lot of teams to be honest," Hoffman said of Anderson.
Kulikowski is excited for the tournament to begin.
"We're going to have fun and enjoy the moment," he said.
Baseball Regional
Northern Division I
4 p.m. Reed at Galena; Spanish Springs at Bishop Manogue; McQueen at Carson; Damonte Ranch at Reno.


text:
Music writer speaks on entering the music industry
By Ruben Paquian - Updated on September 27, 2017 at 11:16 pm
From writing for Grammy Magazine and Forbes, to performing in the same lineup with the likes of Kendrick Lamar and Lupe Fiasco, Ogden Payne has found himself in the center of music industry.
KVRX works to grow music diversity initiative
By Andrea Tinning - Updated on September 25, 2017 at 1:26 am
The Austin Music Commission recently began a genre diversity initiative in partnership with UT-Austin to promote artists of color in underrepresented genres of music. KVRX has taken a proactive role by premiering a series called Live ATX at local music venue Hole in the Wall with a cover charge of $3.
Fan finds comfort, builds relationships through The Maine concerts
By Sofia Mendiola - Updated on September 21, 2017 at 12:23 am
Melanie Sarate did not settle for seeing her favorite band just once or twice.
UT student produces sweet DJ tracks as Frooot
By Chris Duncan - Updated on September 20, 2017 at 12:13 am
When her friends jokingly urged her to pick a DJ name, Paty Gomez-Palacio closed and opened her eyes, picking the first thing she saw: fruit.
Rostam takes listeners on a journey through his past with solo debut
Rostam had a heavy hand in determining indie trends since his professional debut, but he's evolved into an important hero in modern music.
Austin Record Convention founder preserves multi-generational love of vinyl
By Jordyn Zitman - Updated on September 17, 2017 at 11:39 pm
Vinyl records have been a major player in the American music industry for almost a century, despite the development of new ways to listen.
Five of the biggest political acts in Austin
By Chris Duncan - Updated on September 11, 2017 at 11:20 pm
With today's divisive political climate, it's impossible to ignore the effect music has on an individual's beliefs. Add Austin's thriving music scene, a variety of local issues and a plethora of strongly opinionated artists, and Austin is a ticking time bomb of political music.
With today's divisive political climate, it's impossible to ignore the effect music has on an individual's beliefs.
Alvvays continues down the beaten path with second album
Whether it's Belle and Sebastian, The Magnetic Fields or PJ Harvey, Alvvays' formula follows a long tradition of the indie and twee pop before it.
Four albums fans never had the chance to hear and maybe never will
Here are some of the most famous lost recordings, what might have happened to them and how they could have impacted music.


Hi, I am interested in your 1957 Ford Thunderbird (stock #AMS6842) listed on Autotrader for $54,995. I'd like to get more information about this vehicle and confirm its availability.
1957 Ford Thunderbird Convertible E-CODE Real nice, P.S. 2-4 Barrel Carburetors, restored three years ago, Rare Bird nest, rare 3 speed manual transmission, handles real nice, radial white wall tires, hardtop & new convertible top, Rare Tonneau cover, continental kit, black on black.


FSC is one of the most widely used ITIL terms in the IT industry. Change is one of the most widely adopted of ITIL processes. Every week in hundreds of thousands of companies worldwide they publish the FSC.
One of the greatest benefits of ITIL is standardisation of language. What are all those sites expected to do? Change all their reports and their documentation to comply with the whims of ITIL? For what benefit? ITIL is supposed to record what the industry does, not mess around with it. ISO20000 (-1 9.2) doesn't care. COBIT (4.1 AI6) doesn't care. MOF (5.2 Key terms) calls it Forward Schedule of Change and we're all friends with MOF now. So it wasn't a compliance thing.
As many folk aready know thanks to Marc Buzina's entry in BOKKED, the Service Transition book itself gets confused and keeps referring to "SC" not "CS".
I'm betting that at this point 90% of all existing schedules of change are called FSC not CS. I think ITIL V3 Edition 2 (to be known on this blog as the ITIL Refresh Refresh) should change it back before we end up with two terms in general usage.
Previous story: No new concepts in the ITIL V3 2nd Edition - the ITIL RefreshRefresh?
Submitted by Simplicity (not verified) on Tue, 2009-09-22 23:23.
The importance of a widely distributed list of changes that includes those scheduled for the distant future, planned in the short term, and those that have recently been made cannot be understated.
What such a list is called is less important than the list itself being comprehensive, easy to access by anybody, easy to understand and relatively easy for anybody to establish the impact to themselves and their services.
What it should be called and what it is called, are two different matters, though. A poll that finds that most people call it 'fred' doesn't mean that 'fred' is the best name for it - or even if the name itself matters much.
I think that 'Change Schedule' or 'Change list' are better than 'Forward Schedule of Changes', simply because they are simpler. They also have the virtue, as has been pointed out, of apparently not meaning only changes to be made, leaving out changes that have recently been made.
I've no objection to FSC, it is, as you say, a commonly understood term in circles where this sort of thing is discussed regularly.
The advantage of replacing it with 'Change Schedule' or 'Change List', apart from clarity, is that the fad of talking about 'going forward', when you mean 'in future' is likely to be short-lived. It's the sort of jargon that catches on for a while, in the geek community, as an exclusive term - people who don't grok it, or use the standard English term, are not hip, or groovy, they're squares. Once such terms become ubiquitous so that even the dimmest manager talks about having Monday meetings 'going forward' and your waitress asks if you'd like anything more 'going forward', you know that it has lost its exclusivity and it's time to invent a new jargon word to confuse everybody.
'Going forward' is now a painful term used by anybody who hopes to use form and style rather than substance; it's the mark of the chap who is always just that little bit late for the trend. So removing the term 'Forward' from the schedule of changes shows that it is a real and important thing, not just a management fad for geek managers who are just that little bit behind the times. After all, what is more pathetic than being just a little behind the times? Being a decade, or more, out of date shows an independence, a reluctance to indulge in fads, possibly, even, it reflects more experience in the field than the callow youths, just out of Uni, who have to grasp for 'happening' terms they hope will make them seem a little bit older, as they'd grow a straggly moustache.
Submitted by skeptic on Wed, 2009-09-23 00:08.
FSC is well established, at least from ITIL V2 in 2001.
For any change the potential advantages should outweigh the cost and impact.
A schedule of change is 90% forward and 10% retrospective "recently been made" (more CFs for you Brad!) and the major interest is in what is coming up. I don't think the name is terribly misleading just a little imprecise.
It is widely used. ITIL V2 set it as the "standard" eight years ago. MOF agrees. COBIT and ISO20000 have no opinion. Why change other than to annoy Microsoft (good) and thousands of Change Managers (bad)?
Submitted by ianclayton on Sun, 2009-09-27 01:43.
ITIL v2 renamed something in common use, and easier to say - to something else - perhaps so they could lay claim to another unique concept within ITIL. Can we please get back to plain English. As for 'Forward' - wonder how that translates - I was sometimes criticized by my mum for occasionally being a bit too 'forward' - better than 'backward' I suppose.
Anyway, a change schedule needs to reflect the chronological timeline of all changes and support the need for example to look back, perhaps to investigate an issue, and look forward to assess risk and allocate resources. If folks insist on sticking with the forward change schedule term thats there choice - but perhaps one day should we ever get a vote - I vote for a 'backward change schedule', and a 'right now change schedule'.
Submitted by skeptic on Sun, 2009-09-27 03:41.
It's not often i disagree with you Ian but I do here.
A FSC is a summary notification to helpdesk and ops and others of what to be ready for - a heads-up; a mapping to ensure changes don't clash; and a way to group changes into windows. The record of changes that have just happened and have happened in the past are in the Change database where they belong. they can be reported if desired but that isn't a schedule and the timeline aspect isn't terribly interesting any more.
Submitted by ianclayton on Sun, 2009-09-27 23:50.
Is the FSC nothging but a query?
Perhaps we are getting past ourselves here. The FSC could be regarded as the result of a query to the change database.... show all future changes of this status to this location or service, within this period. As could the past change schedule, and any that are over the immediate horizon.
Would it help if we regarded the FSC as one type of query against the change system data?
Submitted by ianclayton on Sun, 2009-09-27 23:47.
Submitted by Visitor (not verified) on Wed, 2009-09-23 08:04.
Change Schedule is easier to understand..FSC was hard to establish, often missleading and only accepted according to the introduction of the formerly new ITIL V2 stuff. If we have to review Changes, ITIL and whatever..why not using obvious terms?
Submitted by Simplicity (not verified) on Wed, 2009-09-23 05:27.
Annoying Change Managers is a bad thing?
As you can see in the other thread, essential as Change Managers are, they're not always every techie's friend. This is, I think, because the ITIL notion of a 'Standard Change' [which includes proper communication and approval] is not properly deployed. It's in the techie's interest to submit and test a standard change so that he doesn't have the hassle of updating the configuration or remembering who to tell or the risk of being blamed for catastrophes.
There's another, serendipitous, benefit, revealed in this thread. Changing the name gives another reason to publicise the process, to discuss what the list means and why it is important. Any raising of awareness is a good thing.
In my experience, too, any Change Manager, worth his salt, is made of sterner stuff than to be annoyed by something so minor.
Submitted by buraddo on Mon, 2009-09-21 16:16.
"FSC is one of the most widely used ITIL terms in the IT industry. Change is one of the most widely adopted of ITIL processes. Every week in hundreds of thousands of companies worldwide they publish the FSC."
"I'm betting that at this point 90% of all existing schedules of change are called FSC not CS."
Submitted by skeptic on Sun, 2009-09-27 01:01.
OK Brad, you win. I plead guilty to having promulgated a CF. The proportion of schedules of change called a FSC is not 90% at all, it is - according to rigorous scientific research based on best IT practice - about 60%. Schedules named FSC only outnumber schedules named CS by 2 to 1. One can only conjecture however on what the proportion would be if V3 had not changed the name three years ago.
Submitted by ianclayton on Sun, 2009-09-27 01:34.
Hang on a minute... what about pre-ITIL and the non-ITIL audiences?
Submitted by buraddo on Sun, 2009-09-27 01:33.
I only saw 44% for FSC..
Submitted by skeptic on Sun, 2009-09-27 03:45.
Submitted by skeptic on Mon, 2009-09-21 21:04.
Submitted by ianclayton on Mon, 2009-09-21 17:06.


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HUAWEI AppGallery Bolsters Itself with the Availability of Pakistan's No. 1 Payments App Easypaisa
In a bid to enrich the HUAWEI AppGallery experience, more and more financial apps are being ported to the world's top third app marketplace
Press ReleaseLast Updated: Aug 17, 2020
HUAWEI AppGallery, the world's top third app marketplace is growing by leaps and bounds. Since its global launch in April 2018, the AppGallery is available in over 170 countries/regions, with 420 million monthly active users globally as of March, 2020. In Pakistan alone, Huawei has been bringing the top 100 apps based on user reviews on its AppGallery, with the most recent addition of Pakistan's No. 1 Payments App Easypaisa.
The inclusion of Easypaisa on the HUAWEI AppGallery had long been anticipated. Now, Huawei users can access their Easypaisa wallet and do all their expense transactions, pay bills, accept remittances – to truly adopt a digital way of life. The arrival of Easypaisa heralds a feat as the HUAWEI AppGallery advances on porting leading financial apps from Pakistan on its marketplace.
As Pakistan's No. 1 Payments App Easypaisa went live on the HUAWEI AppGallery, Scott Huang, Country Manager, Huawei Pakistan observed: "Our consumers have shown a growing interest in the HUAWEI AppGallery by using it to download apps, and revel in the true Huawei experience. The HUAWEI AppGallery has swiftly grown to become the top third app marketplace around the world, bolstered by Huawei's global domination as the No. 01 smartphone brand in Q2 2020. In Pakistan alone, we have seen more and more people use the HUAWEI AppGallery to not only get their favourite apps, but also submit their wish lists for apps to be ported to the platform. Therefore, we are elated to bring Pakistan's leading digital payment platform Easypaisa on the AppGallery to give our consumers a remarkably convenient experience."
Huawei has been hard at work to bolster its AppGallery for its consumers, while the applications on the platform got a total download of 210 billion times within 2019. Consequently, the Huawei Mobile Services (HMS) Ecosystem has achieved rapid growth globally. By July 2020, Huawei has over 700 million monthly active device users. The number of registered developers worldwide has reached 1.6 million while more than 81,000 applications have integrated with HMS Core.
While sharing his thoughts on the development, M. Mudassar Aqil, President & CEO of Telenor Microfinance Bank remarked: "Being Pakistan's No. 1 Payments App means that we are available to anyone who wishes to gain access to the Easypaisa wallet. Therefore, our inclusion on the HUAWEI AppGallery is synced with our aim to increase the Easypaisa customer base, of which we saw a notable growth in the year 2019 with 6.4 million mobile wallet users. The collaboration between Telenor Microfinance Bank and Huawei proclaims our growing relationship with the latter's consumer base – a bond that we look forward to nurture, much like the association with all our customers across Pakistan."
Huawei also debuted their Petal Search Widget – Find Apps, which is already available for download via HUAWEI AppGallery. The new search tool offers Huawei users an open gateway to a million apps – with convenience and ease to download and install them right away. This search tool is the one-stop solution for all your application needs on a Huawei device. You can find apps like HBL, Daraz, ARY News, Askari Bank, Geo News, My Zong, Hum TV, Zameen, Pakistan Railways and much more! Meanwhile hundreds of major new apps continue to be added to the AppGallery every week.


text:
State, National News
World briefly for Nov. 9
WASHINGTON (AP) — Lawmakers are working on a set of new and unprecedented Iran sanctions that could prevent the Islamic republic from doing business with most of the world until it agrees to international constraints on its nuclear program, officials say.
The bipartisan financial and trade restrictions amount to a "complete sanctions regime" against Tehran, according to one congressional aide involved in the process. But it could put the Obama administration in a difficult position with allies who are still trading with Iran, but whom the U.S. needs if it is to secure a peaceful solution to the Iranian nuclear standoff.
On Thursday, in its first foreign policy announcement since the president's re-election, the administration targeted four Iranian officials and five organizations with sanctions for jamming satellite broadcasts and blocking Internet access for Iranian citizens.
But the measures that Sen. Mark Kirk, R-Ill., and Sen. Robert Menendez, D-N.J., want to attach to a defense bill would be far more sweeping. They would target everything from Iranian assets overseas to all foreign goods that the country imports, building on the tough sanctions package against Tehran's oil industry that the two lawmakers pushed through earlier this year, congressional aides and people involved in the process said. Those earlier measures already have cut Iran's petroleum exports in half and hobbled its economy.
Yet even as the value of its currency has dropped precipitously against the dollar in a year, sparking an economic depression and massive public discontent, Iran's leadership has yet to bite on an offer from world powers for an easing of sanctions in exchange for several compromises over its nuclear program. To break the logjam, the administration is brainstorming ways to make the offer more attractive for the Iranians without granting any new concessions that would reward the regime for its intransigence, according to administration officials who spoke on condition of anonymity because they weren't authorized to speak publicly on the matter.
High fliers? Marijuana votes in Colorado, Washington state raise specter of pot tourism
DENVER (AP) — Hit the slopes — and then a bong?
Marijuana legalization votes this week in Colorado and Washington state don't just set up an epic state-federal showdown on drug law for residents. The measures also open the door for marijuana tourism.
Both measures make marijuana possession in small amounts OK for all adults over 21. The measures affect not just state residents but visitors, too. Tourists may not be able to pack their bowls along with their bags, but as long as out-of-state tourists purchase and use the drug while in Colorado or Washington, they wouldn't violate the marijuana measures.
That's assuming the recreational marijuana measures take effect at all. That was very much in doubt Friday as the states awaited word on possible marijuana lawsuits from the federal government.
Obama to address 'fiscal cliff,' setting tone for negotiations with Republicans
WASHINGTON (AP) — Newly re-elected President Barack Obama will use a White House appearance to set the tone for upcoming talks with congressional Republicans on avoiding the so-called fiscal cliff.
Republicans continue to draw a line in the sand against higher tax rates for upper-income earners as they seek to topple the conventional wisdom that Obama has the upper hand in upcoming negotiations on averting the potentially economy-crippling set of tax increases and automatic spending cuts due to hit in January.
Obama faces a tough, core decision: Does he pick a fight and risk a prolonged impasse with Republicans or does he rush to compromise and risk alienating Democrats still celebrating his victory?
Many of his Democratic allies hope Obama will take a hard line when he addresses the matter Friday. Republicans warn that a fight could poison efforts for a rapprochement in a bitterly divided Capitol and threaten his second-term agenda.
Obama has been silent since his victory speech early Wednesday morning, but Capitol Hill Republicans have filled the vacuum with vows to stand resolutely against any effort by the president to fulfill a campaign promise to raise the top two income tax rates to Clinton-era levels.
Gasoline rationing begins in NYC; power outages continue to stymie recovery efforts
NEW YORK (AP) — A new gasoline rationing plan that lets motorists fill up every other day goes into effect in New York as a nor'easter that knocked out power to hundreds of thousands of new people erased some of the progress made by utility crews.
Police will be at gas stations Friday morning to enforce the new system in New York City and on Long Island.
"This is designed to let everybody have a fair chance, so the lines aren't too oppressive and that we can get through this," Mayor Michael Bloomberg said.
The nor'easter brought gusting winds, rain and snow on Wednesday and early Thursday before it moved on. Snow blanketed several states from New York to New England and stymied recovery efforts from Superstorm Sandy as additional storm-weakened trees snapped and more power lines came down.
Hundreds of thousands of utility customers, mostly in New York and New Jersey, have been left still waiting for their electricity to come back on — and some are losing patience, demanding investigations of utilities they say aren't working fast enough.
Defense officials: 7 Navy SEALs punished for disclosing classified information to video maker
WASHINGTON (AP) — Seven members of the secretive Navy SEAL Team 6, including one involved in the mission to get Osama bin Laden, have been punished for disclosing classified information, senior Navy officials said Thursday.
Four other SEALs are under investigation for similar alleged violations, one official said.
The SEALs are alleged to have divulged classified information to the maker of a video game called "Medal of Honor: Warfighter."
Each of the seven received a punitive letter of reprimand and a partial forfeiture of pay for two months. Those actions generally hinder a military member's career.
The deputy commander of Naval Special Warfare Command, Rear Adm. Garry Bonelli, issued a statement acknowledging that nonjudicial punishments had been handed out for misconduct, but he did not offer any details.
Gabby Giffords faces man who went on deadly Arizona rampage as judge orders life in prison
TUCSON, Ariz. (AP) — The pain was palpable, measured in silent stares in the courtroom between an emotionless murderer and wounded former congresswoman who looked her attempted killer in the eyes for the first time since he shot her in the head.
Gabrielle Giffords limped to the podium Thursday, her astronaut husband by her side, inside a packed Tucson courtroom before a judge ordered Jared Lee Loughner to spend the rest of his life in prison.
It was the first time since the January 2011 shooting rampage that his victims would get a chance to speak their minds directly to him. Loughner sat silent, but appeared to absorb every word, his blank gaze fixed on each victim as they scolded him, told stories of their pain and loss and recounted those horrific moments when gunfire changed their lives forever.
"You killed six innocent people," said Giffords' husband, Mark Kelly. "Her life has been forever changed. Plans she had for our family and her career have been immeasurably altered. ... Every day is a continuous struggle to do those things she once was so good at."
Giffords, wearing a black brace around her torso, looked closely at the 24-year-old Loughner for several minutes without uttering a word.
Balkan asylum seekers come under suspicion amid exodus to wealthy EU nations
BUJANOVAC, Serbia (AP) — Azra Ajeti's fellow Gypsies have been buffeted by accusations of filing bogus asylum claims in the rich EU, but she says there's nothing phony about her family's life of misery. "We are starving," said the woman from this impoverished southern Serbian town. "Life here is a disgrace."
Ajeti's son was among some 60,000 people from Serbia and other Balkan countries who have sought asylum in Western Europe since the EU allowed visa-free travel from their nations three years ago. Many EU and local officials describe the exodus as little more than a fraud in which mostly Gypsy migrants cross over knowing their asylum requests have no chance, their main goal to obtain the food, lodging and, in some cases, living expenses worth hundreds of euros (dollars) per month they are entitled to while awaiting an answer.
As a result of the continued surge, the EU states with the most Balkan asylum requests — Germany, Sweden, Belgium, the Netherlands, France and Luxembourg — are moving toward re-imposing visas for Serbia and Macedonia, the two countries that send the most asylum applicants.
Many seekers, however, cite racial discrimination in their home countries as the reason for their flight, saying it constitutes legitimate grounds for asylum.
"Everybody wants to leave," Ajeti said while selling old clothes that she picked out of garbage cans on the dusty streets of Bujanovac. "If I had money for a bus ticket, I would pack up and go right this instant."
Parents in Iraq's second city fear for children after pair of girls abducted, raped and killed
BASRA, Iraq (AP) — The brutal crimes struck a nerve, even in a country that has seen a horrific amount of bloodshed in the past decade: Young Iraqi girls kidnapped, repeatedly raped and then bludgeoned to death in two separate incidents near the southern city of Basra.
Despite a conviction in one case, a handful of arrests in the other and beefed up police patrols in the city, families in Basra remain on edge following the murders of 4-year-old Banin Haider and 5-year-old Abeer Ali in a span of less than two months.
Now, many parents in and around the city won't let their children go to school alone or even play outside after class is out, fearing their daughters, too, could be snatched off the streets, sexually abused and murdered. Others are making plans to leave Basra altogether, saying they have lost confidence in the security forces' ability to keep children safe.
"These inhuman crimes make me think of the safety of my children," said Hazim Sharif, 38, a government employee and father of four. "I do not trust the security forces any more. I have to protect my family by myself."
To many in Iraq, the murders mark a new, more menacing type of violence than the country has previously encountered — at least in public.
UN warns that 4 million people in Syria will likely need humanitarian aid in early 2013
UNITED NATIONS (AP) — The United Nations is warning that the number of people inside Syria needing humanitarian aid could rise sharply from 2.5 million now to 4 million by early next year if the civil war grinds on at its current deadly pace.
John Ging, operations director for the U.N. humanitarian office, said the U.N. is also projecting that a failure to end the fighting will lead to an increase in the number of Syrians fleeing to neighboring countries, from almost 400,000 at present to around 700,000 in early 2013.
Ging spoke in an interview ahead of Friday's fifth Syria Humanitarian Forum in Geneva where between 350 and 400 representatives of governments, international organizations and aid groups will hear reports on the sharply deteriorating humanitarian situation in Syria.
"People need to be aware of just how desperate the situation is inside Syria for the people there, how unbearable it is, and how they are suffering and falling into ever deeper despair and humanitarian need," Ging said. "It's just getting a lot worse very rapidly for the ordinary people."
At the moment, he said, the U.N. and other aid organizations are only able to reach 1.5 million of the 2.5 million people in need of assistance inside Syria — and one of the reasons is funding.
Group says hunt for warlord Kony hopeless without more troops, increased American involvement
KAMPALA, Uganda (AP) — An advocacy group says the hunt for the African warlord Joseph Kony is hopeless without more troops and urges American forces to "play a more operational role" on the ground.
The U.S.-based Enough Project said in a report released Friday that the fight against the Lord's Resistance Army is not going well partly because Ugandan soldiers in central Africa face multiple logistical and intelligence challenges that limit their ability to locate the rebels.
President Barack Obama roughly a year ago sent 100 U.S. Special Forces troops to help regional governments eliminate Kony, an accused war criminal, and other LRA commanders, but they only play an advisory role. About 2,500 African Union troops led by Uganda are involved in the manhunt.


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Congratulations to our YESPhilly April graduates! See our Facebook page for more pictures.
We celebrated our Cycle 4 graduation at our new space at Broad and Lehigh. Congratulations to our newest graduates!
Come and See What YESPhilly Is Up to at Our New Space!


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Home > Museum and Artwork > The College Mace
The College Mace
The College Mace. Sterling silver gilt. With crown surmount and raised Glasgow coat of arms. Inscribed "This Mace Presented to the RFPSG, by James Walker Downie to Commemorate the Granting of the Prefix 'Royal' to its title by HM King Edward 1910". The actual design and execution of the mace was by Mr Frank Lutiger of West Kensington, London.
Messrs. J. Seaton and Co., London
Messrs. J. Seaton and Co., London, "The College Mace," Heritage, accessed January 28, 2023, https://heritage.rcpsg.ac.uk/items/show/32.
Title: The College Mace
Description: The College Mace. Sterling silver gilt. With crown surmount and raised Glasgow coat of arms. Inscribed "This Mace Presented to the RFPSG, by James Walker Downie to Commemorate the Granting of the Prefix 'Royal' to its title by HM King Edward 1910". The actual design and execution of the mace was by Mr Frank Lutiger of West Kensington, London.
Creator: Messrs. J. Seaton and Co., London
Identifier: 2019/3


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meTalk mobile is licensed prepaid calling service in the USA, Global and ETL Dialer Services for the Middle East, Asia, operated by Mesh Telecom Inc. since 2008. Our proven network guarantees clear and reliable calls. We are providing calling cards and web-based management system with great rates to all Latin America, Africa and other all countries around the world. The meTalk mobile calling card is designed to save your money on international calls. Our rates are some of the lowest in the market and in many cases the lowest you find anywhere.
For Symbian platform, meTalk Mobile Dialer is compatible with mobile handsets with OS version S60 2nd; 3rd; and 5th edition. Popular brands which are compatible with meTalk Mobile Dialer on Symbian platform are Nokia, Samsung, Sony Ericsson, Motorola, LG etc.
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meTalk Mobile Dialer is a mobile client for making VoIP calls from mobile phone. It has a user-friendly interface which allows the user to make VoIP calls with great ease.
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Are designed to measure insulation capacitance whilst submerged in a water cooling trough (high pressure water connectors are available for applications where spray water cooling is employed).
Integrate seamlessly with the Proton Products NEXiSTM CS2G-CAP Production Line Control system for capacitance-driven control of extruders or capstan drives in insulation extrusion lines.
Water-submerged measurement of cable insulation capacitance.
10, 25, and 60mm maximum diameter models available.
Fitted with high pressure water inlet and outlet for applications where a water cooling trough is not used.
Ceramic lined end-caps are available for sealing smaller diameter cables.
Manufacture of capacitance critical cables such as coaxial cable for telecommunications and RF.


When it comes to summertime in the UK, there aren't many better places to soak it all up than Cornwall. In fact, Cornwall in the sunshine feels more like being abroad than being in Britain. We're talking baking heat, cooling sea breezes and downright fabulous scenery. Add to that: Cornish ice cream, Cornish pasties and umm… Cornish fudge, and it's hard to imagine anywhere better to spend your July than down on the South West coast.
Tucked away in a secluded cove on the best beach in the country (The Sunday Times' words, not ours), there are few better spots in the land to dine al fresco on a sunny summer's evening than over at Lusty Glaze Beach.
Boasting breathtaking views from its stunning open-air terrace, this beachside bar & restaurant serves up everything from seafood linguine to rib eye steak (…the classic fish and chips is a particular favourite of ours). And what's more, visit during one of the restaurant's legendary Sundowner Sessions and you'll enjoy your salted cracked black pepper burger (another superb choice) to the soothing sounds of one of Cornwall's hottest local artists.
Yep, taking place every Wednesday night throughout the summer, July's line-up includes a whole host of home-grown talent including acoustic trio Ferris V3, singer-songwriter Noel Prior and the supremely talented Ben Morgan-Brown. Long story short, if you're in Newquay this month, you'll want to head down to Lusty Glaze Beach.
What with summer now well and truly upon us, we decided that July's 'Drink' feature had to be somewhere boasting stunning ocean views, a sun-soaked outdoor terrace and (as always) delicious, ice cold beer. Somewhere like… The Slope.
Lending its name from the iconic hill that leads down to Great Western Beach (a hangout spot for surfers since way back in the '60's), The Slope is a retro surf bar with a buzz. Now in it's second year, this laid back beach boozer follows in the footsteps of its proverbial forefather, No.5 Brewhouse, in that it offers up the same insta-worthy dirty burgers, the same locally roasted coffee and the same phenomenal beer courtesy of Sharp's brewery – only this time, in an all new beachfront location.
Our next stop this month is Porthallow, near the iconic fishing village of Looe, where you'll find the gloriously extravagant Talland Bay Hotel.
But although each of the 22 bedrooms are individually furnished, the bizarre decor doesn't often extend inside of them – each room is appointed in a stylish yet lavish manner. Location-wise, you're a short walk down to both the beach and the start of the Cornish coastal path, whilst the Eden Project is a short journey by car.
As it happens, Talland Bay Hotel could quite easily have made a play for this month's 'Eat' segment, owing to its two hugely popular dining options headed up by top chef Nick Hawke. The lavish double AA-rosette Terrace Restaurant boasts a contemporary, fine-dining menu that uses fresh, local ingredients and changes twice a week; whilst the Conservatory brasserie offers a slightly more relaxed setting with equally tasty fare. It's the brilliance of both of these spaces that saw the hotel named the 'Best Restaurant in the South West' at the Taste of the West Awards in 2017.
Admittedly, rooms at Talland Bay don't come all that cheap. But if you're looking for a slightly more luxurious (and distinctly characterful) base for your Cornwall adventure this month, this fabulously wacky hotel should be right at the top of your list.
Over in Charlestown, one of Cornwall's most picturesque villages (thanks in part to its stunning Georgian harbour), the annual regatta week is one of the standout events of the year. Taking place from Saturday 21st July this year, Regatta Week is jam-packed with awesome goings on from boat races to comedy shows and even floral dance processions. And as though that wasn't enough, the whole thing is in support of local community projects and charities.
This year's highlights include Thursday's extravagant Grand Carnival; Friday's Regatta Rocks (an evening of open air live music); whilst Saturday sees the return of the annual raft races, where teams of four adults/juniors bring along their home-made rafts and go head to head for titles such as 'speediest raft', 'best junior raft' and 'most entertaining senior raft'.
All entrants are welcome, but beware: it' gets competitive – and "missiles" ARE allowed. Crikey.
It's Never Too Late to… Travel Solo!


Artemis is the Greek Goddess of the Moon, hunting, child birth, Wilderness and Wild animals. She is the daughter of Zeus and Leto and her twin brother is Apollo.
Artemis was a great hunter and hunted in the woods of Arcadia where she lived with her seven nymphs. Everyone was afraid of upsetting the Greek Godess so she lived alone with the company of just her seven nympths. A brave young mortal by the name of Orion was afraid of very little and he was in love with one of her nymphs named Merope. One day he was hunting in the woods when he saw Artemis's nympths he ran after them and they sprinted away quickly but Orion was just as fast. He reached out to grab Merope's tunic as she ran, but Artemis heard their cries for help and quickly transformed them into seven white doves. Artemis required Zeu's help to protect them and he quickly turned them into stars that people called the 'Pleiades'. Artemis then turned onto Orion but when she saw how brave, strong, beautiful and fast he was she was amazed. They quickly grew close to each other and became fast friends. They would challenge each other to foot racing, archery, hunting and storytelling. Apollo loved his sister and grew jealous of their friendship. Artemis told him that Orion is heroic when Apollo asked how she could love a meer mortal which angered the God. One Night when Orion was asleep he dreamed of a deadly giant scorpion which he could neither kill or even wound. When he awoke he was drenched in sweat and panicking. But when he realized that it was just a dream he he got up to go outside but there waiting for him was the deadly scorpion sent by Apollo. A deadly battle erupted and he fought viciously but just like in the dream he could not pierce the beast's armour. Eventually the scorpion backed Orion towards the sea and Orion jumped in and swam away. Artemis was lying on the shore when Apollo came and told her that an evil man by the name of Candaeon had attacked one of her forest priestesses and was swimming in the sea to escape from Artemis. Artemis was furious that someone had attacked one of her own and when Apollo told her that the distance figure floating in the water was actually Candaeon she immediately shot an arrow at it with perfect accuracy. Later on Orion's body washed up to the shore with her own arrow sticking out of his head and then Artemis realized her mistake. Artemis took him in her silver Moon chariot up to the sky and placed hime in the stars with his two loyal hounds and the Scorpion as an honor of their friendship.


Gel filtration chromatography separates molecules on the basis of size and shape. This experiment provides a LyphoSample™ mixture of RNA and DNA that is separated on a gel exclusion column. The purified fractions of DNA and RNA are analyzed by agarose gel electrophoresis.
Kit includes: instructions, DNA/RNA LyphoSample™, Dry matrix, elution buffer, chromatography columns, agarose, gel loading solution, buffer, InstaStain® Blue and FlashBlue™ stain.
All You need: electrophoresis apparatus, power supply, ring stands with clamps, automatic micropipet with tips, microwave or hot plate, pipet pumps or bulbs, 5 or 10 ml pipets, balance, lab glassware, weigh boats, white light visualization system, photodocumentation system (optional), distilled water.


No longer support from STM.
The X-NUCLEO-IDW04A1 Wi-Fi evaluation board is based on the SPWF04SA module. The SPWF04SA module has an embedded STM32 MCU, a low-power Wi-Fi b/g/n SoC with integrated power amplifier and power management, and an SMD antenna.
The SPWF04SA module relies on 2 MB MCU internal Flash. 1 MB of the internal Flash is for storing the user file system and to perform secure firmware update over the air (FOTA).
A hardware interface allows the use of external memory to extend file system storage capability with no size limit.
The firmware includes a complete IP stack, dynamic web pages with SSI to interact with the module and a REST API (get & post) for conveniently transferring files to and from servers in the cloud.
The module can simultaneously behave as a socket server and socket client.
The firmware supports secure sockets with TLS encryption, ensuring secure end-to-end communications with the cloud.
The X-NUCLEO-IDW04A1 interfaces with the MCU on the STM32 Nucleo board via the UART serial port and/or SPI interface.
For connect SPWF04Sx evaluation board to the PC, I suggest to use the STM Serial to USB bridge (STEVAL-PCC018V1) see the image below.
On PC we use TeraTerm.
The TeraTerm must be configured as shown below.
REPL stands for Read Evaluation Print Loop and it is the std name given to the interactive MicroPython Prompt that is also enabled on SPWF04S.
Typically used for debugging purposes, it is by far the easiest way to test interactively the code and run commands.
On SPWF04S, AT+S.python command launched without parameters and the CTRL-D escape character are respectively used to enter and to leave the REPL.
When the UART console is set on the module a python script can be launched by using the AT+S.python command with the script specified as its parameter.
MicroPython scripts are developed using a standard offline text editor, and then moved for execution on SPWF04S Wi-Fi module.
After the script execution, the control returns to the UART AT Console.
By using the GPIO(8) set to high at the boot time, or when console_enabled is set to 3, the module automatically enters the execution of the script specified by the configuration variable "python_script".
This mode allows to use the module without a connected host.
this means that on following reboot, to access again the python mode, GPIO(8) must be high again.
The Figure below summarizes the MicroPython modes described above.
This variable is defined to set the console on SPWF04S.
This setting allows using MicroPython together with the UART console and by referring to the MicroPython modes it enables both the REPL and the Run time script modes.
this setting allows only a MicroPython preloaded script to be executed.
No UART/SPI communication is allowed to/from an Host processor when this mode is enabled.
To choose the amount of memory to reserve for MicroPython script/REPL execution.
The default value is 32 (in unit of 1024 bytes).
Identifies the script to be executed when console_enabled is set to 3 (PYTHON_ONLY).
The default value is "3:/uPython_test.py" (a ROM resident example script).
This GPIO has been reserved to enter PYTHON_ONLY mode via HW, no matter console_enabled configuration variable value is set to.
If GPIO(8) level is high at startup, than MicroPython script pointed by python_script configuration variable is executed, and AT command/SPI protocol cannot be used.
When Micropython is active the GPIO(14), PWR_LED, is driven to make some execution steps visible with a LED connected to that GPIO.
See Table below for specific behaviors in the different use modes.
This function is disabled when GPIO(14) is used as the MOSI signal in a SPI connection.
Note 2. See paragraph 2.2 for a list of possible REPL commands.
The PWR_LED is on when the scripts is running.
At every reboot the script pointed by the python_script variable is executed.


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Classic Fight: Vasiliy Lomachenko gets past tough test from Jorge Linares
Jorge Linares was the defending champion, but Vasiliy Lomachenko passed another test in 2018.
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Vasiliy Lomachenko was the favorite two years ago when he met Jorge Linares at Madison Square Garden, but he was not the defending champion. That was Linares, who came in with the WBA lightweight title, with Lomachenko moving up to look for a world title in a third weight class, something Linares had already achieved.
Lomachenko, 30 at the time, was already considered a pound-for-pound elite with his 10-1 (8 KO) record on the way in. He'd lost his second pro fight in 2014, but that proved merely a speed bump. He learned from the defeat, made some adjustments to the pro game after a legendary amateur career, and became the fighter he was expected to be.
After winning world titles at 126 and 130, Lomachenko had run out of willing opponents in a second weight class, so it was up to lightweight, where he found the highly skilled Linares (44-3, 27 KO coming in) waiting with open arms.
Linares, 32, had had his own setbacks, but more or less had become the fighter expected from his early days in the pros, when his upside was routinely lauded, and for good reason. At his best, Linares has been one of the best purely skilled boxers to come around in years. Vulnerable? Yes. But a wonderful boxer when on his game.
Linares was on his game against Lomachenko. He put Vasiliy down in the sixth round, but he wound up stopped in the 10th all the same, passing the belt to the Ukrainian star. It was as much a testament to Lomachenko's skills as anything we've seen in the pro game thus far; Linares was fighting a good fight, and he got him out anyway. At the time of the stoppage, scores were 85-85, 86-84 Linares, and 86-84 Lomachenko.
In other words, this was a competitive, high-level fight between two guys with a ton of skills, and I think it's worth another look. As we know, Linares still wants a rematch, and one would expect if he can fight his way back to one, Lomachenko would be plenty willing, if he's still got belts by then.
Full Fight: Lomachenko gets past tough test from Linares
Full Fight: Spence breaks through, takes first world title from Brook


Rapid developments in science and technology are changing the way research is conducted by academia and business. The global networking of researchers ans information professionals is one key driver of accelerated scientific and technological change, for it leads new research trends and findings to quickly spread around the globe. Yet another key driver is competition between national scientific systems, which promotes greater efficiency and innovation. As a result of this new environment, researchers are placing new and greater demands on information infrastructure. It is imperative for us as a leading international provider of information infrastructure services to recognize and respond to new trends early on. Accordingly, we closely examine the issues and challenges faced by our users and customers. This ensures that our services are closely tailored to practical needs.
This covers topics such as text mining, semantic methods, the development of ontologies for generating high-value content as well as new methods for the inquest/query, analysis and visualization.
In this context, FIZ Karlsruhe offers students to conduct Bachelor- or Master- theses (Diplomarbeiten) on the mentioned subject. Of course, internships in this field are possible too. Topics which are currently offered you can find here.