Sea creatures continue to fascinate people all over the world with their unique adaptability. These magnificent sea animals have bodies perfectly shaped to thrive and survive in the Earth's oceans and seas. They respond better to their environmental requirements because they have a hydrodynamic form with little understood sensory abilities, complex communication systems and the ability to survive despite human impact on their habitat. Recent documentaries have unveiled their social skills which have been exploited to some extent by the military. Dolphins, for example, are generally very friendly animals which amaze us by their learning and communicative capabilities. These sea animals and as well as whales and sharks are a leading example of perfect symbiosis with their surroundings which can lead the way for people to start building improved technology for ocean exploration.
The whale is a marine mammal pertaining to the cetacea family which includes the blue whale and the humpback whale among many other species. They can live for an extensive period of up to 100 years. Whales feed on microscopic plankton which they can filter from sea water through their mouth plates and on krill from the Arctic Ocean. Toothed whales can eat fish and squid. To find their prey they have developed a very smart sound system called echolocation. Whales emit sound signals which reach animals and receive an echo signal from the animal touched by sound waves. This echo enables whales to determine the position of the next meal. The shark is a fish with a cartilaginous skeleton which has inhabited the seas since the time of dinosaurs. Shark species include the great white, the tiger shark, the hammerhead shark and many other. The shark has a predator structure with powerful jaws, sharp teeth and streamlined body with a durable skeleton. It feeds on fish, marine mammals and other types of marine food. The dolphin is a marine mammal related to whale. They are social and smart animals which have extensive learning capabilities. The dolphin feeds on fish and squid. Species include the spotted dolphin, the bottlenose dolphin.
The whale can be found in all oceans over the world. The shark is traceable in all seas and usually inhabits the sea section between 2,000 and 3,000 meters (6,500 to 9,800 feet) deep. The dolphin can be found in all seas mostly near the coastline in shallow water.
A whale can reach up to 35 m (115 ft.) and weigh over 100 tons. A shark can reach up to 6 m (20 ft.) and weigh up to 1,900kg (4,200 lbs.). A dolphin can reach up to 9.5 m (30 ft.) and weigh up to 10 tons.
The whale and dolphin are related marine mammal species, while the shark is a fish.
Whales can be found in all seas just like dolphins and sharks. Sharks prefer deeper water, while dolphins are traceable in shallow water.
The whale is bigger in size and weight than the shark and the dolphin.
Whales, dolphins and some shark populations are suffering due to over fishing and inadequate protection from illegal poachers.
Military sonar has caused untold damage to these creatures as they live by use of their own sonar capabilities and can be damaged by artificial weaponry bases on sonar.
Garbage in the oceans may be a key reason why some dead whales and dolphins have tested at high rates of poison by weight. Human garbage dumps in the oceans is problem which needs to be addressed and solved for our posterity as well as for the ocean's inhabitants.
Which ocean creature is most playful?
Great comparison. I really like the way you put this article together. My thoughts go to killer whales because of their very social lifestyles and hunting methods.
Crocodile vs. Alligator: How are they different?
Jersey vs. Holstein Cow: What's the difference?
African vs. Asian Elephants: How are they different?


Scientifically speaking, there are two ways to learn German as a foreign language: the unsupervised method – picking it up on the street – or the structured approach in classes.
A mixture of both is probably best. Experienced language institutes prefer to use a varied blend of exercises for speaking, listening, writing, reading and vocabulary as well exercises as for pronunciation and grammar in their learning programs. These are supplemented by elements of regional studies.
Classes are in German right from the beginning, which creates an authentic feeling. The goal is to give students a basic knowledge of everyday German. Then they can go out onto the street to practice and improve on it.
In case you want to learn perfect German, Munich's "Spotlight Verlag" publishes the magazine "Deutsch perfekt" (www.deutsch-perfekt.com). Every month, correspondents from Germany, Austria and Switzerland write articles about society, politics and other topics. In addition, the magazine provides advice for people who want to live or work in Germany.
There are articles for beginners, intermediate and advanced students. Thus, students of all levels benefit from the magazine. New words are explained in simple German and there is an extensive vocabulary section with cards you can collect. "Deutsch perfekt" costs € 7.50 per issue at the newsstand. A one-year subscription costs € 80.40.


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CCCC > Archive > 2003, Volume 68 > Issue 12 > p. 2231 > Cited by
Crossref Cited-by Linking
Moe May Myat, Benny Jonathan, Liu Jianbo: Collision-induced dissociation of homodimeric and heterodimeric radical cations of 9-methylguanine and 9-methyl-8-oxoguanine: correlation between intra-base pair proton transfer originating from the N1–H at a Watson–Crick edge and non-statistical dissociation. Phys. Chem. Chem. Phys. 2022, 24, 9263. <https://doi.org/10.1039/D2CP00312K>
Parkan Ali, Mirzaei Mahmoud, Tavakoli Naser, Homayouni Alireza: Molecular interactions of indomethacin and amino acids: Computational approach. MGC 2022, 21, 611. <https://doi.org/10.3233/MGC-210157>
Liu Yue, Ma Congcong, Leonen Calvin J. A., Chatterjee Champak, Nováková Gabriela, Marek Aleš, Tureček František: Tackling a Curious Case: Generation of Charge-Tagged Guanosine Radicals by Gas-Phase Electron Transfer and Their Characterization by UV–vis Photodissociation Action Spectroscopy and Theory. J. Am. Soc. Mass Spectrom. 2021, 32, 772. <https://doi.org/10.1021/jasms.0c00459>
Park Gyuri, Kang Byunghwa, Park Soyeon V, Lee Donghwa, Oh Seung Soo: A unified computational view of DNA duplex, triplex, quadruplex and their donor–acceptor interactions. Nucleic Acids Research 2021, 49, 4919. <https://doi.org/10.1093/nar/gkab285>
Kaur Sarabjeet, Sharma Purshotam, Wetmore Stacey D.: Can Cyanuric Acid and 2,4,6‐Triaminopyrimidine Containing Ribonucleosides be Components of Prebiotic RNA? Insights from QM Calculations and MD Simulations. ChemPhysChem 2019. <https://doi.org/10.1002/cphc.201900237>
Kaur Sarabjeet, Sharma Purshotam, Wetmore Stacey D.: Structural and electronic properties of barbituric acid and melamine-containing ribonucleosides as plausible components of prebiotic RNA: implications for prebiotic self-assembly. Phys. Chem. Chem. Phys. 2017, 19, 30762. <https://doi.org/10.1039/C7CP06123D>
Masoodi Hamid Reza, Bagheri Sotoodeh, Abareghi Mahsa: The effects of tautomerization and protonation on the adenine–cytosine mismatches: a density functional theory study. Journal of Biomolecular Structure and Dynamics 2016, 34, 1143. <https://doi.org/10.1080/07391102.2015.1072734>
Hudecová Jana, Profant Václav, Novotná Pavlína, Baumruk Vladimír, Urbanová Marie, Bouř Petr: CH Stretching Region: Computational Modeling of Vibrational Optical Activity. J. Chem. Theory Comput. 2013, 9, 3096. <https://doi.org/10.1021/ct400285n>
Dračínský Martin, Jansa Petr, Bouř Petr: Computational and Experimental Evidence of Through-Space NMR Spectroscopic J Coupling of Hydrogen Atoms. Chemistry A European Journal 2012, 18, 981. <https://doi.org/10.1002/chem.201102272>
Kessler Jiří, Jakubek Milan, Dolenský Bohumil, Bouř Petr: Binding energies of five molecular pincers calculated by explicit and implicit solvent models. J. Comput. Chem. 2012, 33, 2310. <https://doi.org/10.1002/jcc.23063>
Banáš Pavel, Mládek Arnošt, Otyepka Michal, Zgarbová Marie, Jurečka Petr, Svozil Daniel, Lankaš Filip, Šponer Jiří: Can We Accurately Describe the Structure of Adenine Tracts in B-DNA? Reference Quantum-Chemical Computations Reveal Overstabilization of Stacking by Molecular Mechanics. J. Chem. Theory Comput. 2012, 8, 2448. <https://doi.org/10.1021/ct3001238>
Benda Ladislav, Straka Michal, Sychrovský Vladimír, Bouř Petr, Tanaka Yoshiyuki: Detection of Mercury–TpT Dinucleotide Binding by Raman Spectra: A Computational Study. J. Phys. Chem. A 2012, 116, 8313. <https://doi.org/10.1021/jp3045077>
Lim Siew Choo, Bowler Matthew W., Lai Ting Feng, Song Haiwei: The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1. Nucleic Acids Research 2012, 40, 11009. <https://doi.org/10.1093/nar/gks792>
Chawla Mohit, Sharma Purshotam, Halder Sukanya, Bhattacharyya Dhananjay, Mitra Abhijit: Protonation of Base Pairs in RNA: Context Analysis and Quantum Chemical Investigations of Their Geometries and Stabilities. J. Phys. Chem. B 2011, 115, 1469. <https://doi.org/10.1021/jp106848h>
Panigrahi Swati, Pal Rahul, Bhattacharyya Dhananjay: Structure and Energy of Non-Canonical Basepairs: Comparison of Various Computational Chemistry Methods with Crystallographic Ensembles. Journal of Biomolecular Structure and Dynamics 2011, 29, 541. <https://doi.org/10.1080/07391102.2011.10507404>
Klusák Vojtěch, Dobeš Petr, Černý Jiří, Vondrášek Jiří: How to fragment a polypeptide? An ab initio computational study of pair interactions between amino acids and ligand-amino acids in proteins. Collect. Czech. Chem. Commun. 2011, 76, 605. <https://doi.org/10.1135/cccc2011033>
Sharma Purshotam, Šponer Judit E., Šponer Jiří, Sharma Sitansh, Bhattacharyya Dhananjay, Mitra Abhijit: On the Role of the cis Hoogsteen:Sugar-Edge Family of Base Pairs in Platforms and Triplets—Quantum Chemical Insights into RNA Structural Biology. J. Phys. Chem. B 2010, 114, 3307. <https://doi.org/10.1021/jp910226e>
Svozil Daniel, Hobza Pavel, Šponer Jiří: Comparison of Intrinsic Stacking Energies of Ten Unique Dinucleotide Steps in A-RNA and B-DNA Duplexes. Can We Determine Correct Order of Stability by Quantum-Chemical Calculations?. J. Phys. Chem. B 2010, 114, 1191. <https://doi.org/10.1021/jp910788e>
Sharma Purshotam, Sharma Sitansh, Chawla Mohit, Mitra Abhijit: Modeling the noncovalent interactions at the metabolite binding site in purine riboswitches. J Mol Model 2009, 15, 633. <https://doi.org/10.1007/s00894-008-0384-y>
Wu Yan, Sa Rongjian, Li Qiaohong, Wei Yongqin, Wu Kechen: Theoretical studies on the bonding of Cd2+ to adenine and thymine: Tautomeric equilibrium and metalation in base pairing. Chemical Physics Letters 2009, 467, 387. <https://doi.org/10.1016/j.cplett.2008.11.073>
Parchaňský Václav, Matějka Pavel, Dolenský Bohumil, Havlík Martin, Bouř Petr: Modeling of a Tröger's tweezer and its complexation properties. Journal of Molecular Structure 2009, 934, 117. <https://doi.org/10.1016/j.molstruc.2009.06.030>
Ran Jiong, Hobza Pavel: Nature of Bonding in Nine Planar Hydrogen-Bonded Adenine···Thymine Base Pairs. J. Phys. Chem. B 2009, 113, 2933. <https://doi.org/10.1021/jp810001v>
Lippert Bernhard, Gupta Deepali: Promotion of rare nucleobase tautomers by metal binding. Dalton Trans. 2009, 4619. <https://doi.org/10.1039/b823087k>
Saha Saumitra, Wang Feng: N-K spectra of adenine amino tautomers. J Phys Conf Ser 2009, 185, 012040. <https://doi.org/10.1088/1742-6596/185/1/012040>
Neihsial Siamkhanthang, Lyngdoh Richard H. Duncan: Novel H-bonded base dimers as repeat units for information-bearing self-associative duplexes: A B3LYP/6-31G* search. J Comput Chem 2008, 29, 1788. <https://doi.org/10.1002/jcc.20942>
Dkhissi Ahmed, Blossey Ralf: Metahybrid Density Functional Theory and Correlated ab Initio Studies on Microhydrated Adenine−Thymine Base Pairs. J. Phys. Chem. B 2008, 112, 9182. <https://doi.org/10.1021/jp803110n>
Kapitán Josef, Hecht Lutz, Bouř Petr: Raman spectral evidence of methyl rotation in liquid toluene. Phys. Chem. Chem. Phys. 2008, 10, 1003. <https://doi.org/10.1039/B713965A>
Sharma Purshotam, Mitra Abhijit, Sharma Sitansh, Singh Harjinder, Bhattacharyya Dhananjay: Quantum Chemical Studies of Structures and Binding in Noncanonical RNA Base pairs: The Trans Watson-Crick:Watson-Crick Family. Journal of Biomolecular Structure and Dynamics 2008, 25, 709. <https://doi.org/10.1080/07391102.2008.10507216>
Kabeláč Martin, Sherer Edward C., Cramer Christopher J., Hobza Pavel: DNA Base Trimers: Empirical and Quantum Chemical Ab Initio Calculations versus Experiment in Vacuo. Chem. Eur. J. 2007, 13, 2067. <https://doi.org/10.1002/chem.200601007>
Schreiber Marko, González Leticia: Structure and bonding of Ag(I)-DNA base complexes and Ag(I)-adenine-cytosine mispairs: An ab Initio study. J. Comput. Chem. 2007, 28, 2299. <https://doi.org/10.1002/jcc.20743>
Bhattacharyya Dhananjay, Koripella Siv Chand, Mitra Abhijit, Rajendran Vijay Babu, Sinha Bhabdyuti: Theoretical analysis of noncanonical base pairing interactions in RNA molecules. J Biosci 2007, 32, 809. <https://doi.org/10.1007/s12038-007-0082-4>
Sharma Purshotam, Mitra Abhijit, Sharma Sitansh, Singh Harjinder: Base pairing in RNA structures: A computational analysis of structural aspects and interaction energies. J Chem Sci 2007, 119, 525. <https://doi.org/10.1007/s12039-007-0066-9>
Krishnan G.M., Kühn O.: Identifying adenine–thymine base pairing by anharmonic analysis of the hydrogen-bonded NH stretching vibrations. Chemical Physics Letters 2007, 435, 132. <https://doi.org/10.1016/j.cplett.2006.12.072>
Harries William E.C., Khademi Shahram, Stroud Robert M.: The role of tryptophan cation���pi interactions on ammonia transport through the AmtB ammonia channel. International Congress Series 2007, 1304, 15. <https://doi.org/10.1016/j.ics.2007.07.054>
Yao Chunxiang, Tureček František, Polce Michael J., Wesdemiotis Chrys: Proton and hydrogen atom adducts to cytosine. An experimental and computational study. Int J Mass Spectrosc 2007, 265, 106. <https://doi.org/10.1016/j.ijms.2007.01.013>
Wolken Jill K., Yao Chunxiang, Tureček František, Polce Michael J., Wesdemiotis Chrys: Cytosine neutral molecules and cation–radicals in the gas-phase. Int J Mass Spectrosc 2007, 267, 30. <https://doi.org/10.1016/j.ijms.2007.02.016>
Schreiber Marko, González Leticia: The role of Ag(I) ions in the electronic spectroscopy of adenine–cytosine mispairs. J Photochem Photobiol A Chem 2007, 190, 301. <https://doi.org/10.1016/j.jphotochem.2007.01.035>
Sundaresan Neethu, Suresh Cherumuttathu H.: A Base-Sugar−Phosphate Three-Layer ONIOM Model for Cation Binding: Relative Binding Affinities of Alkali Metal Ions for Phosphate Anion in DNA. J. Chem. Theory Comput. 2007, 3, 1172. <https://doi.org/10.1021/ct600245w>
Černý Jiří, Jurečka Petr, Hobza Pavel, Valdés Haydée: Resolution of Identity Density Functional Theory Augmented with an Empirical Dispersion Term (RI-DFT-D): A Promising Tool for Studying Isolated Small Peptides. J. Phys. Chem. A 2007, 111, 1146. <https://doi.org/10.1021/jp066504m>
Andrushchenko Valery, Wieser Hal, Bouř Petr: DNA Oligonucleotide−cis-Platin Binding: Ab Initio Interpretation of the Vibrational Spectra. J. Phys. Chem. A 2007, 111, 9714. <https://doi.org/10.1021/jp074572i>
Kabeláč Martin, Hobza Pavel: Hydration and stability of nucleic acid bases and base pairs. Phys. Chem. Chem. Phys. 2007, 9, 903. <https://doi.org/10.1039/B614420A>
Pluháčková Kristýna, Jurečka Petr, Hobza Pavel: Stabilisation energy of C6H6⋯C6X6 (X = F, Cl, Br, I, CN) complexes: complete basis set limit calculations at MP2 and CCSD(T) levels. Phys. Chem. Chem. Phys. 2007, 9, 755. <https://doi.org/10.1039/B615318F>
Tureček František: Modeling Deoxyribonucleic Acid and Ribonucleic Acid Damage in the Gas Phase. Eur J Mass Spectrom (Chichester) 2007, 13, 89. <https://doi.org/10.1255/ejms.848>
Kubař Tomáš, Hanus Michal, Ryjáček Filip, Hobza Pavel: Binding of Cationic and Neutral Phenanthridine Intercalators to a DNA Oligomer Is Controlled by Dispersion Energy: Quantum Chemical Calculations and Molecular Mechanics Simulations. Chem. Eur. J. 2006, 12, 280. <https://doi.org/10.1002/chem.200500725>
Zendlová Lucie, Hobza Pavel, Kabeláč Martin: Potential Energy Surfaces of the Microhydrated Guanine⋅⋅⋅Cytosine Base Pair and its Methylated Analogue. Chem. Eur. J. of Chem. Phys. 2006, 7, 439. <https://doi.org/10.1002/cphc.200500311>
Sen Kakali, Basu Samita, Bhattacharyya Dhananjay: Ab initio studies on excited state intramolecular electron transfer in 4-amino-N-methylphthalimide and 3-amino-N-methylphthalimide. Int. J. Quantum Chem. 2006, 106, 913. <https://doi.org/10.1002/qua.20866>
Kourafalos Vassilios N., Marakos Panagiotis, Mikros Emmanuel, Pouli Nicole, Marek Jaromír, Marek Radek: Synthesis and tautomerism study of 7-substituted pyrazolo[3,4-c]pyridines. Tetrahedron 2006, 62, 11987. <https://doi.org/10.1016/j.tet.2006.09.081>
Liu Yuemin, Hu Xiche: Molecular Determinants for Binding of Ammonium Ion in the Ammonia Transporter AmtBA Quantum Chemical Analysis. J. Phys. Chem. A 2006, 110, 1375. <https://doi.org/10.1021/jp054261c>
Herbert Holly Elizabeth, Halls Mathew D., Hratchian Hrant P., Raghavachari Krishnan: Hydrogen-Bonding Interactions in Peptide Nucleic Acid and Deoxyribonucleic Acid: A Comparative Study. J. Phys. Chem. B 2006, 110, 3336. <https://doi.org/10.1021/jp055865j>
Otyepka Michal, Sklenovský Petr, Horinek Dominik, Kubař Tomáš, Hobza Pavel: How the Stabilization of INK4 Tumor Suppressor 3D Structure Evaluated by Quantum Chemical and Molecular Mechanics Calculations Corresponds Well with Experimental Results: Interplay of Association Enthalpy, Entropy, and Solvation Effects. J. Phys. Chem. B 2006, 110, 4423. <https://doi.org/10.1021/jp056890s>
Sundaresan Neethu, Pillai C. K. S., Suresh Cherumuttathu H.: Role of Mg2+ and Ca2+ in DNA Bending: Evidence from an ONIOM-Based QM-MM Study of a DNA Fragment. J. Phys. Chem. A 2006, 110, 8826. <https://doi.org/10.1021/jp061774q>
Haley Terence P., Graybill Eric R., Cybulski Slawomir M.: Ab initio calculations of dispersion coefficients for nucleic acid base pairs. The Journal of Chemical Physics 2006, 124, 204301. <https://doi.org/10.1063/1.2197832>
Downton M. T., Wang F.: Differentiation of adenine non-planarity in valence molecular orbitals. Molec Sim 2006, 32, 667. <https://doi.org/10.1080/08927020600860911>
Auweter Sigrid D., Oberstrass Florian C., Allain Frédéric H.-T.: Sequence-specific binding of single-stranded RNA: is there a code for recognition?. Nucleic Acids Research 2006, 34, 4943. <https://doi.org/10.1093/nar/gkl620>
Harris Sarah Anne: Modelling the biomechanical properties of DNA using computer simulation. Phil. Trans. R. Soc. A. 2006, 364, 3319. <https://doi.org/10.1098/rsta.2006.1906>
Hobza Pavel, Zahradník Rudolf, Müller-Dethlefs Klaus: The World of Non-Covalent Interactions: 2006. Collect. Czech. Chem. Commun. 2006, 71, 443. <https://doi.org/10.1135/cccc20060443>
Vondrášek Jiří, Bendová Lada, Klusák Vojtěch, Hobza Pavel: Unexpectedly Strong Energy Stabilization Inside the Hydrophobic Core of Small Protein Rubredoxin Mediated by Aromatic Residues: Correlated Ab Initio Quantum Chemical Calculations. J. Am. Chem. Soc. 2005, 127, 2615. <https://doi.org/10.1021/ja044607h>
Kabeláč Martin, Zendlová Lucie, Řeha David, Hobza Pavel: Potential Energy Surfaces of an Adenine−Thymine Base Pair and Its Methylated Analogue in the Presence of One and Two Water Molecules: Molecular Mechanics and Correlated Ab Initio Study. J. Phys. Chem. B 2005, 109, 12206. <https://doi.org/10.1021/jp045970d>
Bouř Petr, Andrushchenko Valery, Kabeláč Martin, Maharaj Vanitha, Wieser Hal: Simulations of Structure and Vibrational Spectra of Deoxyoctanucleotides. J. Phys. Chem. B 2005, 109, 20579. <https://doi.org/10.1021/jp051218g>
Brauer Brina, Gerber R. Benny, Kabeláč Martin, Hobza Pavel, Bakker Joost M., Abo Riziq Ali G., de Vries Mattanjah S.: Vibrational Spectroscopy of the G· · ·C Base Pair: Experiment, Harmonic and Anharmonic Calculations, and the Nature of the Anharmonic Couplings. J. Phys. Chem. A 2005, 109, 6974. <https://doi.org/10.1021/jp051767m>
Černý Jiří, Hobza Pavel: The X3LYP extended density functional accurately describes H-bonding but fails completely for stacking. Phys. Chem. Chem. Phys. 2005, 7, 1624. <https://doi.org/10.1039/B502769C>
Dąbkowska Iwona, Jurečka Petr, Hobza Pavel: On geometries of stacked and H-bonded nucleic acid base pairs determined at various DFT, MP2, and CCSD(T) levels up to the CCSD(T)/complete basis set limit level. The Journal of Chemical Physics 2005, 122, 204322. <https://doi.org/10.1063/1.1906205>
Bera Partha Pratim, Schaefer Henry F.: (G–H) • –C and G–(C–H) • radicals derived from the guanine·cytosine base pair cause DNA subunit lesions. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 6698. <https://doi.org/10.1073/pnas.0408644102>
Guallar Victor, Borrelli Kenneth W.: A binding mechanism in protein–nucleotide interactions: Implication for U1A RNA binding. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 3954. <https://doi.org/10.1073/pnas.0500888102>
Fanfrlík Jindřich, Rejnek Jaroslav, Hanus Michal, Hobza Pavel: Hydration Gibbs Energies of Nucleic Acid Bases Determined by Gibbs Energy Perturbation, Continuous and Hybrid Approaches. Collect. Czech. Chem. Commun. 2005, 70, 1756. <https://doi.org/10.1135/cccc20051756>
Sečkářová Pavlı́na, Marek Radek, Maliňáková Kateřina, Kolehmainen Erkki, Hocková Dana, Hocek Michal, Sklenář Vladimír: Direct determination of tautomerism in purine derivatives by low-temperature NMR spectroscopy. Tetrahedron Letters 2004, 45, 6259. <https://doi.org/10.1016/j.tetlet.2004.06.088>

redpajama_set_name: RedPajamaCommonCrawl


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Naked Bulb – Sixth Sense
Leg Two | 6:30 PM - 7:30 PM | Agave
Beast Crawl 2017 presents Naked Bulb Press - Sixth Sense. The Bulb is honored to be a part of the Crawl's sixth year! and it's seventh year as an East Bay, monthly open-mic in Fruitvale. Naked Bulb is an open performance space for veterans and newbies, especially for those who have not been heard. What started as an open-mic has now expanded to a local press.
Curator: Missy Church
Missy Church is the founder of Naked Bulb Press and the author of, CHURCH - a Retrospective, by Paper Press. Her upcoming poetry collection, CATECHISM, will be released this fall. Missy also curates a small museum - Animal Hospital.
Event Readers
Bill Gainer
Bill Gainer is internationally published and known across the country for giving legendary fun filled performances. Visit him in his books, at his personal appearances, or at his website: billgainer.com.
Steve Goldberg is a perplexed Cleveland street poet that is now more confused by living in the central Piedmont of North Carolina and also a veteran Beastie from the beginning.
Laura A. Zink
Kwan Booth
Laura A. Zink is an editor for MARY: A Journal of New Writing. Her fiction has appeared in Full of Crow, sPARKLE & bLINK, and Naked Bulb 2016 Summer Anthology.
Kwan Booth is an award winning writer and strategist focused on the intersection of media, technology and social justice. He's the editor of the anthology "Black Futurists Speak: New Black Writing" and his journalism and creative writing have been published in anthologies, journals and news sites. Boothism.org
Iwalani Venerable
Andrew J. Thomas
Iwalani Venerable aka LaniGrooves is a Bay area native residing in Oakland. She is a musician, performing artist, film maker and educator she loves inspiring others with the power of music LaniGrooves produces composes and writes her own original music.
Andrew J. Thomas is a father, a husband, and a poet. He lives in Vacaville, CA with a dog, a cat, a wife, and until recently, two teenage sons. He has no classic training in the art of the written word, other than years of heart break and a love of whiskey. He is a founding member and alumnus of the Beast Crawl Literary Festival and enjoys participating and supporting literary events in the Bay Area. His first book of poetry, Strangeland, was recently published by none other than Naked Bulb Press. He hopes his poems make you cry because then maybe he can too.
William Taylor Jr.
William Taylor Jr. lives and writes in the Tenderloin neighborhood of San Francisco. His work has been published widely in journals across the globe, including The New York Quarterly, The Chiron Review, and Catamaran Literary Reader. He is the author of numerous books of poetry, and a collection of short fiction. He is a Pushcart Prize nominee and was a recipient of the 2013 Kathy Acker Award. To Break the Heart of the Sun is his latest collection of poetry. He recently edited Cockymoon: Selected Poems of Jack Micheline, published by Zeitgeist Press in 2017.


We kunnen fietsreizen op maat organiseren in de regio's waar we al hebben gefietst en dus de routes kennen.
"On behalf of the entire group and most especially my Nancy, we wanted to thank you sincerely for constructing and executing an absolutely fantastic bicycling adventure for our group. Not only was the planning perfect, not lost on us was all of the additional work and worrying that was required, as you often had to bicycle double routes and try to find us when we somehow got lost, simply following the river bank !?!
Not only were the sights and activities perfectly suited to our interest, you were a great addition to this group of close friends, as we considered you fully part of the team."
en wij bellen uw terug wanneer u wilt.


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Quynh Lam: Improvement is Paramount
By Staff in Club & League
Improvement is Paramount
Name: Quynh Lam
Resides: Northville, MI
Occupation: Attorney
Favorite Stroke: Forehand
Tennis Goals: Improve the serve and net game
Motivating Words: No pain, no gain.
Quynh Lam probably spends more time watching tennis than she should, but who could blame her? "Tennis has been really exciting since 2005 and 2006," she says by way of explanation.
Her favorite ATP player is Rafael Nadal "because of his unique style and the charisma and intensity that he brings to the game." Lam thinks Nadal has brought a new excitement to the sport. "He's one of a kind. Tennis was a bit boring before he arrived on the scene," she explains.
Andy Murray and Juan Martin del Potro also rank high on her list, while Serena Williams, Victoria Azarenka and Vera Zvonareva are favorites on the WTA side.
Watching the top players' elegant and powerful shots inspires her to hit the courts to work on her own skills.
"I think I have an aggressive style and like to attack when I can," Lam says. "There are many areas of my game that I'm constantly working on. I love it when I've improved an aspect of my game."
Lam plays tennis to stay active because the mental and physical challenges of the sport are more enjoyable than other forms of exercise. She plans to take her "intermediate" game to the next level, while reminding herself: No pain, no gain.
Are you passionate about tennis? Email your story to editorial@TennisViewMag.com
This article is from the Jan/Feb '14 - Maria Sharapova issue
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text:
Q: Nginx Round Robin Load balancing Upstream Servers are not in sequential order, behaviour changes between chrome,firefox,IE browsers Configured Nginx Server in a Virtual box(ubuntu server) and opened up the port 80 to windows host,
Did the same to 5 Ubuntu servers with a basic node app that prints 1,2,3,4,5 with 5 servers respectively.
Configured the Nginx.conf file
events{
}

http{
        upstream serverslist {
#               Server 8001
                server 192.168.100.2:3000;
#               Server 8002
                server 192.168.100.3:3000;
#               Server 8003
                server 192.168.100.4:3000;
#               Server 8004
                server 192.168.100.5:3000;
#               Server 8005
                server 192.168.100.6:3000;
        }
        server {
                location / {
                        proxy_pass      "http://serverslist/";
                }
        }
}

Ping and Curl to these servers individually from the Nginx server works perfectly and returns the expected result.
I.e on each
curl localhost gives 1, 2, 3, 4, 5, 1, 2, 3, 4, 5. In this order. which is expected.
But when I load the Nginx server in Chrome Browser I get the output 1, 3, 5, 2, 4, 1, 3, 5, 2, 4.
And When I load the Nginx server in Firefox I get the output 1, 2, 3, 4, 5. (Correct)
When I load the Nginx IP in the duckduckgo browser on android it gives 5, 4, 3, 2, 1, 5, 4, 3, 2, 1.
I tried adding many proxy-based headers and just plain headers from the net, couldn't find any solution to get the same output in all browsers i.e 1, 2, 3, 4, 5, 1, 2, 3, 4, 5. On Each reload of the same server.
Any help would be great.

A: Edit 3: Found out an interesting issue.
In chrome every time I access my website it makes two calls no matter what they are called to/of my website and /favicon.ico of my website.
I don't have a /favicon.ico.
What I think is happening

*

*when Nginx is getting requests for/of my website, it is loading the first server upstream.

*when chrome loads / from my website it also calls /favicon.ico of my website which results in making a new call to Nginx so it loads the .ico files from the next server upstream.

*this happens so that servers 1,2,3 are loaded in order 1(ico file from 2),3(ico file from 1),2(ico file from 3). and cycle repeats.

once I stopped the loading of /favicon.ico in Nginx, my three upstreams servers 1,2,3 are loading in order 1,2,3 of round-robin.
I put this in the server with upstream to disable loading favicon.ico from Nginx.
location = /favicon.ico {
  log_not_found off;
}

Hope anyone having this problem find this useful.
Edit 2: Figured out the issue, the load balancing is working fine with static files and static servers inside the Nginx conf file.
but my applications are being loaded by node, so had to start Nginx after starting all the node servers.
Issue reappears when I restart the application server while Nginx is running.
Now no issue will update soon
Edit 1: This is not working for me anymore, this worked yesterday, today continued working on the same configuration, the issue reappeared.
Had this same issue with my setup.
What worked for me after a lot of proxy setup and VirtualBox setup and network editing.
Add an extra server block in the HTTP block.
server{
}

and reload the Nginx service.
It worked for me, after reloading once both chrome and firefox loads the servers in the given order, I deleted the server block and it is still working.
Don't know why the issue raised in the first place.
Hope this helps to solve your issue.

redpajama_set_name: RedPajamaStackExchange


text:
PTC Network
June, 09 2020
Its big and rapid strides in information and entertainment industry have helped Punjabi to grow from a regional to a global language. PTC Network has been magnificently expanding its grip globally by establishing its identity as world's most popular and largest Punjabi television network with millions of viewers across the globe. Till date the network has launched 7 linear channels – PTC Punjabi, PTC News, PTC Chak De, PTC Gold, PTC Simran, PTC Dhol TV, PTC Music in addition to 90 Face book pages, 6 websites, 4 twitter handles, 6 YouTube channels, 1 audio label, a 360 degree event management unit, a call center, 9 studios and 1 OTT platform under the ambit of G Next Media Pvt. Ltd.
PTC Network is the only Indian television company to have full-fledged production studios in USA & Canada. PTC Network is also world's only company producing one digital Punjabi Film every week. More than 80% of original Punjabi television content in the world is produced and owned by PTC Network. The Network also has many firsts to its credit including a 360 degree Virtual Reality channel PTC VR.
Another first is, PTC Dhol TV – first ever live FB channel streaming Punjabi music 24X7. The company has over 400 best of the media talent, 6 state-of-the-art studios and 9 operational offices in national and international locations, including New Delhi, Mohali, Amritsar, Mumbai, London, New York, Mississauga (Ontario).
The prime focus of the network is to popularize and promote Punjab, Punjabi and Punjabiyat to its massive audience spread all across the globe. In its commitment to have a meaningful impact on the lives of millions of Punjabi viewers across the world, the Network has introduced various programming ventures that are quite popular. PTC Network provides numerous interesting programmes through its bouquet of channels pertaining to the interest of its viewers – comprising of Punjabi entertainment, news, music, spiritual, sports and much more.
RULING GLOBALLY WITH QUALITY CONTENT
More than 80% of the original Punjabi television content in the world is produced and owned by PTC Network. PTC's content library includes feature films, short films, documentaries, serials, reality shows, talent shows, ground events for telecast, songs and much more. On an average, PTC Network produces over 17 hours of fresh content every day! And hence the network stands atop as undisputed leader for years and has been ruling the roost.
BRINGING GURBANI TO EVERY HOME
Holding the reputation of being the first ever Punjabi satellite channel and also credited with bringing Gurbani on world's television, the network has achieved a special place in the heart of its viewers, especially Punjabi community residing world over. Currently, PTC Punjabi is the sole channel broadcasting Gurbani live from Sri Harmandir Sahib (Golden Temple), Amritsar for more than 8 hours a day.
PROVIDING PLATFORM TO TALENT
PTC Network has always endeavored to acknowledge and honour the talent in the Punjabi entertainment industry. By organizing some of the biggest events in the Television and Entertainment industry, such as PTC Punjabi Music Awards and PTC Punjabi Film Awards, the network has always tried to bring forth the best of the talented artists and is continuously working to promote Punjab, Punjabi & Punjabiyat.
Praj Industries
Apex Insurance Consultant Ltd.
Ahmed Food
Muppa Projects
Nutrezy Bars
Priyadarshani Group of Schools
Online Legal India


text:
#ifndef DB4_UTILS_H
#define DB4_UTILS_H

#include "db_cxx.h"
#include "mod_db4_export.h"

/* locks */
int env_locks_init();
void env_global_rw_lock();
void env_global_rd_lock();
void env_global_unlock();
void env_wait_for_child_crash();
void env_child_crash();
void env_ok_to_proceed();

void env_rsrc_list_init();

int global_ref_count_increase(char *path);
int global_ref_count_decrease(char *path);
int global_ref_count_get(const char *path);
void global_ref_count_clean();

#endif
/* vim: set ts=4 sts=4 expandtab bs=2 ai fdm=marker: */

redpajama_set_name: RedPajamaGithub


text:
The Outlaw Orchestra ~ Back Under The Covers ~ NEW RELEASE
During the worldwide lockdown a year or so back The Outlaw Orchestra continued writing and recording, keeping us entertained on a weekly basis with video cover songs recorded from their various corners of the UK. That collection of covers ended up as a release on digital music platforms named 'Under The Covers'.
"We never intended those covers to be reviewed in the music press, what started out as a way to beat the lockdown blues was picked up and gained momentum, folk loved it and we had a blast working together at virtual distance" said frontman Dave Roux.
Having released their 2nd full album 'Makin' Tracks' in October 2021 to overwhelming reviews the ensuing festivals and gigs have kept them hard on the road with little chance to book studio time for new material. However the band explain:
"When backstage hanging with other bands and musicians, we like to warm up the fingers and voices jamming out covers. Everyone joins in, the bottle tops start to collect pretty fast and within an hour we're stage ready. This is how we started out, busking around the kitchen table swapping instruments. Someone backstage said 'you guys should record these, they're great fun'. So with the help of portable technology we captured the more polished versions of our backroom jams into another collection of our favourite covers."
'Back Under The Covers' demonstrates the guys' breadth of tastes from The Beatles' 'Come Together', The Small Faces' 'Itchy Coo Park' via The Bands' 'Up On Cripple Creek' and having toured with Phil Campbells Ba***** Sons there's a stripped-back version of Motorheads' 'Iron Fist'. They flex their heavier rock personality as well showing their country roots and love of British 60'/70's rock.
It was recently said in a live review "What makes them an Orchestra? They're a three piece." It's probably due to the plethora of instruments they play at any gig, its an Orchestra's worth of strings; Banjo, Mandolin, Lap Steel, Pedal Steel, Guitars, Baritone guitars and every percussive instrument you can fit in a van. All of these make their way onto the new collection of tracks.
Dave Roux surmises "Its our salute to our heroes and record collections that keep us inspired."
The Outlaw Orchestra have more in the pipeline having recently worked with Kris Barras on a video release due out in December and a cracking B-side to accompany that single. Grab yourself a cold one and get Back Under The Covers with The Outlaw Orchestra.


text:
Mendon kids enjoy puppet party
Morgan Rousseau/Daily News staff
Dozens of children showed up at Clough Elementary School last night to soak in the visual splendor of a colorful marionette show at the Taft Library's End of Summer Reading Party.
To mark the end of the program, two puppeteers from Tanglewood Marionettes, a Ware-based company, performed "The Dragon King," a story taken from Chinese folklore.
Children's Librarian Andrew Jenrich said he wanted to expose the children to a different culture for their final event, because the summer reading program's theme was "One World, Many Stories," and focused on diversity. "I wanted to present them with something multicultural," said Jenrich. "The story is set on the other side of the world, so I thought it would be nice to try (Tanglewood) out - I'd heard great things about their performances."
Tanglewood puppeteers Peter Schaefer and Jennifer Tebo performed the 50-minute show in the Clough cafeteria to a crowd of children, parents, volunteers and Friends of Taft Public Library.
Tanglewood's Artistic Director Anne Schaefer said the marionette shows are designed for the entertainment both of children and adults.
"Our shows are a basic theatrical presentation. You can see the puppeteers above the marionettes, but it isn't distracting; it's part of the show," said Shaefer. "There are many layers to watch. We keep in mind that we are targeting a variety of ages."
Puppeteer Peter Schaefer said, "Some people really enjoy the technical aspect of how we perform, others enjoy the artistic stuff. Some of the adults enjoy the show just as much as the kids."
"The Dragon King" follows the story of a drought that has overtaken the Chinese countryside, and the plight of a wise grandmother who journeys to the bottom of the sea to seek the Dragon King, and the answers to why he has forsaken the land above.
Summer reading participant Joshua Watson, 8, said it was his first time watching a marionette show.
"I'm excited to see a dragon," said Watson, adding that he has enjoyed the activities in this year's reading program.
"It's been super fun. I did 25 hours of reading," said Watson.
Children who completed 20 hours of reading or more received prizes such as buttons, erasers, stuffed animals, boomerangs and a certificate. They also had their names placed into a raffle for last night's party.
"We got a lot of generous gift card donations this year," said Jenrich.
Some gift cards were to Barnes & Noble, Dunkin' Donuts, the Mendon Twin Drive-in and Southwick Zoo, to name a few.
To add a little sweetness to the program's end, kids were served ice cream courtesy of the Friends of the Taft Public Library.
Other events this summer have included arts and crafts, story time, a worm race and cooking classes.
Jenrich said he thinks it is important to mark the end of each summer program with a party.
"We try to switch it up every year," said Jenrich. "We will occasionally have someone back to do a performance, but we often like to bring in new performers for the kids to enjoy."
Morgan Rousseau can be reached at 508-634-7546 or at Mrousseau@wickedlocal.com.


text:
Emark DMC
Hotel infrastructure
Zacatecas is a beautiful and romantic destination. It is a city of small sloping streets, ramped and staggered alleys that invites visitors to admire its architectural beauties of pink quarry stone buildings, among them; the Basilica Cathedral of Zacatecas with its baroque style, the Calderon Theater, and other buildings of its historic center which have been declared a World Heritage Site by UNESCO.
Zacatecas comes from the Nahuatl, its name means "inhabitant of the land where grass abounds". In colonial times was the main mining center of New Spain, is still recognized for its deposits of silver, gold and other minerals, for its architecture, museums, traditions and for its courageous participation in one of the great battles of national history "The Mexican Revolution". But also, as the romantic city of México.
To visit Zacatecas is to know the legacy of a wealthy society based on the extraction of silver and gold from the mines discovered in its surroundings. Its beautiful colonial architecture such as the Basilica Cathedral, the Government Palace, the Pedro Coronel Museum, to admire the works of the great masters of art.
For adrenaline lovers, you can enjoy a panoramic view of Zacatecas in cable car that crosses the city from mountain of the "Bufa" to the "Grillo" Mountain. For history lovers, there is the "Toma de Zacatecas" Museum, with 8 rooms that will allow you to learn about the events before and during the battle of Zacatecas and the Fernando Calderon Theater, of neo-renaissance architectural aspect, which will delight you with plays and concerts.
At the Eden Mine you will enjoy an unforgettable visit to an unimaginable place, you will travel by train through the depth of the mine through its rocky tunnels admiring the exhibits of rocks and precious minerals typical of the area and other parts of the world.
Zacatecas International Airport or General Leobardo C. Ruiz International Airport, also known as Calera Airport, is located just 17 kilometers or 30 minutes approximately from the city downtown, receives domestic and international flights; the arrival of domestic and international tourists for business or leisure and rest increases air connectivity by making direct flights to Tijuana, Mexico City, Chicago, Dallas, Los Angeles and San Jose, California.
The number of tourists that receives this airport is mixed because it is a tourist and business city for this reason the airport undergoes a constant adaptation to meet the demands of the two segments of travelers.
The city of Zacatecas currently has approximately 76 hotels with almost 3,000 rooms with five and four stars. Within the hotel infrastructure of Zacatecas can also find halls, gardens and suitable spaces for holding your business meetings. Prestigious hotel chains had trusted investing in this city such as Fiesta Inn, Emporio, Hampton Inn, City Express among others and is constantly growing.
Zacatecana gastronomy has a wide range of rich dishes typical of the region, highlighting the Wedding Roast, so called because it is very common to serve in regional weddings; the Ram "Birria", the "Zacatecan Pacholas" which is beef and pork with chili, the Baked Loin in aluminum foil, the red Pozole, the Zacatecan Enchiladas, the meat stuffed in red chile and the chubby (corn tortillas) stuffed with stews, the Zacatecano Rabbit, are delicacies worth trying.
Enjoy a delicious pastry, with a "Zacatecana capirotada", marshmallows, "charamuscas", coconut candy, guava and quince candies and milk ham, as well as the traditional sweets potato, pumpkin candy.
Zacatecas vineyards produces exquisite table wines; red, rosé and white; its typical zacatecan drink is the mezcal of Huitzila, you can also taste and enjoy local delicacies such as the lenten water, mead and peron and cane wines.
The Palace of the Zacatecas Conventions is located 5 minutes distance from downtown city and 15 minutes from airport, is magnificent and modern with an innovative architectural style, built with ecological technology such as lighting and natural ventilation, ideal for congresses, exhibitions, business meetings, conferences, social and academic events, banquets to concerts and shows, it has an area of 20,000 sq. m. and a capacity to host up to 6,000 people.
Other alternatives available in Zacatecas for these purposes include spectacular gardens, vineyards, mansions, museums, haciendas, and hotels. At Emark DMC ® Zacatecas, we are professionals in the organization of specialized events focused on the operation and logistical support for business tourism, congresses and conventions.
Discover a new night experience in Zacatecas, walk through its streets and alleys of the historic downtown, squares and gardens, until you reach the Alameda with a band that produces music or "Zacatecano drums", is one of the most emblematic traditions called "Callejoneada" music is contagious and the dance inevitable.
Visit traditional bars or canteens such as the famous canteen "the Fifteen letters" with more than 100 years of existence and favorite of some famous people of art and show for a lively and enjoyable atmosphere. At night, you can admire the beautiful, illuminated landscape of the historic center from the heights from the cable car.
Customs & Traditons
The most emblematic traditions are: "La Romería" in honor of our lady the Virgin of Zacatecas, the "Morisma de Bracho" religious festival in honor of St. John the Baptist and is a staging of the Battle of Lepanto between Moors and Christians. "The Procession of Silence" on the Friday of Holy Week. In addition, there are other festivals that often focus on traditional dance recitals and many are derived from waltzes and polkas thanks to the mining history of the state and has great cultural and artistic attractions.
Back to all destinations
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text:
American Rescue Plan Provides Critical Relief to Students, Educators
Post author By Common Dreams
WASHINGTON – Congress today passed a historic economic relief package, the American Rescue Plan, which will provide critical funding to help alleviate suffering felt by millions of Americans.
The following statement can be attributed to NEA President Becky Pringle:
"With today's passage of the American Rescue Plan, we finally have the vital and comprehensive response to provide students, educators, families and hard-working Americans with the desperately needed relief in response to the COVID-19 pandemic and economic crisis. This historic legislation not only provides the resources to help every school building put in place the effective measures needed to keep students and educators safe; it also makes extraordinary investments that will lift countless children and families out of poverty and works to address the immense inequities that have systematically affected the most vulnerable students and communities of color. After months of tireless advocacy, educators gratefully applaud this bill. Now, state and local leaders must work together to ensure all students receive the support, tools and resources they need so that school buildings and college campuses can reopen — and stay open — safely and equitably."
"Since the beginning of the pandemic, NEA members have worked to support students and their families by staying in constant contact with them — witnessing firsthand their desperation, fear and anxiety. At the same time, NEA members have never stopped advocating for what is needed to close the gaps exacerbated by this pandemic or the generations of underfunding schools in communities of color. Through the National Education Association, educators, parents, caregivers, students, and community members wrote hundreds of thousands of messages and placed thousands of calls to senators and representatives over the past year, sharing personal stories about what America's students are facing and what they need to reopen school buildings and college campuses safely and equitably.
"Because of the American Rescue Plan, the lives of America's students, educators and their families will improve in significant ways — including the nearly $170 billion dedicated to public schools and colleges, more than $7 billion for E-Rate to help address the digital divide, the $350 billion in local and state aid to keep frontline workers including educators on the job, and a historic investment in families that will cut child poverty in half.
"We applaud the leadership of President Biden and Vice President Harris, Speaker Pelosi and Leader Schumer and the representatives and senators for getting the job done. This federal legislation will undoubtedly alleviate some of our nation's immense suffering, but there is still much work ahead to fully recover from the worst crisis to hit this country in more than a century — and to build back something better. NEA has outlined proven ways to help students overcome COVID-19 opportunity gaps and meet students' academic, social and emotional needs in a comprehensive plan. We have an unprecedented opportunity to create the public schools all students — Black and white, Native and newcomer, Hispanic and Asian alike — need and deserve. Our work is not over."
Common Dreams | Radio Free (2023-01-28T06:04:51+00:00) » American Rescue Plan Provides Critical Relief to Students, Educators. Retrieved from https://www.radiofree.org/2021/03/10/american-rescue-plan-provides-critical-relief-to-students-educators/.
" » American Rescue Plan Provides Critical Relief to Students, Educators." Common Dreams | Radio Free - Wednesday March 10, 2021, https://www.radiofree.org/2021/03/10/american-rescue-plan-provides-critical-relief-to-students-educators/
Common Dreams | Radio Free Wednesday March 10, 2021 » American Rescue Plan Provides Critical Relief to Students, Educators., viewed 2023-01-28T06:04:51+00:00,<https://www.radiofree.org/2021/03/10/american-rescue-plan-provides-critical-relief-to-students-educators/>
Common Dreams | Radio Free - » American Rescue Plan Provides Critical Relief to Students, Educators. [Internet]. [Accessed 2023-01-28T06:04:51+00:00]. Available from: https://www.radiofree.org/2021/03/10/american-rescue-plan-provides-critical-relief-to-students-educators/
" » American Rescue Plan Provides Critical Relief to Students, Educators." Common Dreams | Radio Free - Accessed 2023-01-28T06:04:51+00:00. https://www.radiofree.org/2021/03/10/american-rescue-plan-provides-critical-relief-to-students-educators/
" » American Rescue Plan Provides Critical Relief to Students, Educators." Common Dreams | Radio Free [Online]. Available: https://www.radiofree.org/2021/03/10/american-rescue-plan-provides-critical-relief-to-students-educators/. [Accessed: 2023-01-28T06:04:51+00:00]
» American Rescue Plan Provides Critical Relief to Students, Educators | Common Dreams | Radio Free | https://www.radiofree.org/2021/03/10/american-rescue-plan-provides-critical-relief-to-students-educators/ | 2023-01-28T06:04:51+00:00
← 'Golden Voted Against Helping the People of Maine': Meet the One Democrat Who Voted No on Covid Relief Bill → Largest Federal Employee Union Applauds Passage of American Rescue Plan Act


text:
Q: jquery ui datepicker not displaying on Chrome and Firefox I am using the jquery ui datepicker in my asp.net website.The datepicker works fine when I run it from Visual Studio on my machine.However,when I host it on IIS on the Test server,the datepicker does not display.My aspx page looks like this:
<script src="http://ajax.googleapis.com/ajax/libs/jquery/1.6/jquery.min.js" type="text/javascript"></script>
<script src="http://ajax.googleapis.com/ajax/libs/jqueryui/1.8/jquery-ui.min.js" type="text/javascript"></script>
<link href="http://ajax.googleapis.com/ajax/libs/jqueryui/1.8/themes/base/jquery-ui.css" rel="Stylesheet" type="text/css" />
<script type="text/javascript">
        $(function () {
            $(".txtDatepicker").datepicker({
                minDate:0,
                showOn: 'button',
                buttonImageOnly: true,
                buttonText: "Calendar",
                buttonImage: 'calendar.gif'
            });
        });

I am trying to display the datepicker inside a gridview:
<asp:GridView ID="grdUnitsData" runat="server" AutoGenerateColumns="false" DataKeyNames="Id" OnRowDataBound="grdUnitsData_RowDataBound" AllowPaging="false" RowStyle-BackColor="White" AlternatingRowStyle-BackColor="LightBlue"  BorderStyle="Solid">
    <RowStyle Height="5px" />
    <AlternatingRowStyle Height="5px" />
    <Columns>
        <asp:BoundField DataField="Id" HeaderText="Identity" Visible="false"/>
        <asp:BoundField DataField="Code" HeaderText="Unit Code" />
        <asp:BoundField DataField="Name" HeaderText="Unit Name" />
        <asp:TemplateField>
            <HeaderTemplate>Start Date</HeaderTemplate>
            <ItemTemplate>
                <asp:TextBox ID="txtStartDate" runat="server" ClientIDMode="AutoID" style="min-width: 25px;" class="txtDatepicker" Text='<%#Eval("StartDate")%>'></asp:TextBox>
            </ItemTemplate>
       </asp:TemplateField>
       <asp:TemplateField>
           <HeaderTemplate>End Date</HeaderTemplate>
           <ItemTemplate>
               <asp:TextBox ID="txtEndDate" runat="server" ClientIDMode="AutoID" style="min-width: 25px;" class="txtDatepicker" Text='<%#Eval("EndDate")%>'></asp:TextBox>
           </ItemTemplate>
       </asp:TemplateField>
    </Columns>
</asp:GridView>

Things I have tried:

*

*Using showOn:'both' instead of showOn:'button'


text:
Кызылту — упразднённый аул в Коченёвском районе Новосибирской области России. Входил в состав Целинного сельсовета. Исключен из учётных данных в 2005 г.

География
Располагался в 8,5 км к северо-западу от поселка Маслово.

История
Упразднён Законом Новосибирской области от 09.12.2005 г № 360-ОСД.

Население
По данным переписи 2002 году в поселке отсутствовало постоянное население.

Примечания

Упразднённые населённые пункты Коченёвского района
населённые пункты, упразднённые в 2005 году

redpajama_set_name: RedPajamaWikipedia


To evaluate the use of intraoperative radiation therapy (IORT) in the multimodality treatment of patients with isolated local recurrences of pancreatic cancer.
We retrospectively analyzed 36 patients with isolated local recurrences of pancreatic cancer who have been treated with a combination of surgery, IORT and EBRT. Median time from initial treatment to recurrence was 20 months. All patients were surgically explored. In 18 patients a gross total resection was achieved, whereas the other half received only debulking or no resection at all. All patients received IORT with a median dose of 15 Gy. Additional EBRT was applied to 31 patients with a median dose of 45 Gy, combined with concurrent, mainly gemcitabine-based chemotherapy.
Median follow-up in surviving patients was 23 months. Local progression was found in 6 patients after a median time of 17 months, resulting in estimated 1- and 2-year local control rates of 91% and 67%, respectively. Distant failure was observed in 23 patients, mainly in liver or peritoneal space. The median estimated progression-free survival was 9 months with 1- and 2-year rates of 40% and 26%, respectively. We found an encouraging estimated median overall survival of 19 months, transferring into 1- and 2-year rates of 66% and 45%. Notably 6 of 36 patients (17%) lived for more than 3 years. Severe postoperative complications were found in 3 and chemoradiation-related grade III toxicity in 6 patients. No severe IORT related toxicity was observed.
Combination of surgery, IORT and EBRT in patients with isolated local recurrences of pancreatic cancer resulted in encouraging local control and overall survival in our cohort with acceptable toxicity. Our approach seems to be superior to palliative chemotherapy or chemoradiation alone and should be further investigated in a prospective setting specifically addressing isolated local recurrences of pancreatic cancer.
Pancreatic cancer is the fourth leading cause of cancer-related death in western countries . Only about 15-20% of the patients are diagnosed in resectable stages . In Europe, the standard of care for those patients consists of surgery followed by adjuvant chemotherapy . But despite some improvements in overall survival by adding adjuvant chemotherapy , the vast majority of the patients still develops an incurable treatment failure. While in most patients the overall outcome is limited by the development of distant metastasis or combined locoregional and distant failure, about 10-35% of patients will develop an isolated local recurrence without evidence for distant spread after curative intended surgery [4, 5]. While surgical resection is the only potential curative treatment approach for pancreatic cancer, and although an isolated local recurrence represents a potentially curable situation, the majority of these patients will be treated with palliative chemotherapy or chemoradiation alone. This raises the question, if a more aggressive local therapy could be beneficial at least for some of these patients. We therefore retrospectively reviewed our patients with isolated local recurrences of pancreatic cancer after primary resection, who have been treated at our institution with a more aggressive approach consisting of surgery, IORT and EBRT.
We identified a total of 42 patients with isolated local recurrences of pancreatic cancer in the database of the University of Heidelberg, who have been treated with IORT between 2002 and 2009. Thirty-six of these patients met the premise of a curative intended treatment, which was defined as surgery without gross residual disease + IORT regardless of additional EBRT, or IORT + EBRT regardless of gross residual disease. These patients formed the basis of current analysis.
The majority of patients were male and median age at first diagnosis was 62 years. The primary treatment in all patients included surgery without macroscopic residual disease. The histological subtype was adeno-carcinoma except in three patients. The majority of patients suffered from locally advanced tumors (T3; n = 29), located in the pancreatic head (n = 29) and showed positive nodal disease (n = 21). The most frequent surgical approaches were Whipple´s procedures (n = 27). About two thirds of the patients received adjuvant chemotherapy, mainly gemcitabine-based (82%). None of the patients received chemoradiation in their primary treatment course. For detailed patient and treatment characteristics in primary situation see Table 1.
FD: first diagnosis, age [years], pp-whipple: pylorus-preserving whipple procedure, adj.: adjuvant, Gem: Gemcitabine, Cis: Cisplatin, 5-FU: 5-Fluororuracil, LV: Leucovorin, FA: Folinic Acid.
Local recurrence was identified by the appearance of clinical symptoms, a growing mass on repeated CT or MRI during regular follow up with a parallel increase of tumor markers or a positive PET-Scan in case of negative tumor markers. After diagnosis of a local recurrence, all patients were restaged with at least chest and abdominal CT to exclude distant metastasis. The median time interval between primary treatment and local recurrence was 20 months (range 6 to 76 months).
All patients were surgically explored and at least biopsied. In 18 patients a gross total resection was achieved, whereas the other half received only a tumor debulking or no resection at all, resulting in gross residual disease. IORT was applied to all patients either to the tumor bed or the region of gross residual disease with a median dose of 15 Gy, using a median electron energy of 8 MeV and a median cone size of 6 cm.
The technique of intraoperative radiation therapy used at the University of Heidelberg has already been described [6, 7]. In brief, IORT was performed in a dedicated surgical theatre with an integrated Siemens Mevatron ME linear accelerator (Siemens, Concord, USA) capable of delivering 6-18 MeV electrons and thus covering a depth up to 6 cm. After the surgical procedure, an applicator of appropriate size was chosen to encompass the target area which was defined in correspondence with the treating surgeon. The applicator was manually positioned and attached to the table. Uninvolved radiosensitive tissues like small bowel were displaced or covered by lead shielding. The applicator was aligned with the linear accelerator using a laser guided air-docking system. The IORT dose was prescribed to 90% isodose, which covered the gross residual disease or the region of suspicious surgical margins with a safety margin of 1 cm.
After staging, 25 patients were judged at least borderline resectable and scheduled for surgery, IORT and postoperative chemoradiation. Of these, 5 patients did not receive postoperative EBRT because of complications or patients refusal (see Figure 1a). The remaining 11 patients were initially judged as not resectable, but responded to neoadjuvant chemoradiation and were scheduled for surgical exploration and IORT (see Figure 1).
Treatment schedule. OP: operation, neoadj. : neoadjuvant, adj. : adjuvant, EBRT : external beam radiation therapy, IORT : intraoperative radiation therapy.
EBRT was performed by linear accelerators using 3D-conformal or intensity-modulated techniques. Patients were treated in supine position using multiple field techniques. The target volume included the gross tumor volume or the surgical tumor bed with a safety margin of 1-2 cm. No elective nodal irradiation was performed. The median EBRT dose was 45 Gy (range 39.6 to 59.4 Gy), applied in conventional fractionation (1.8-2 Gy per fraction, 5 fractions a week). EBRT was combined with concurrent chemotherapy, usually gemcitabine weekly (300 mg/sm), except in one patient. For detailed patient and treatment characteristics for recurrence see Table 2.
Rec.: recurrence, age [years], time to rec. [months], explo. Lap.: explorative laparotomy, IORT: intraoperative radiation therapy EBRT: external beam radiation therapy, neoadj.: neoadjuvant, 3D: three-dimensional CT-based conformal treatment, IMRT: intensity-modulated radiation therapy, all radiotherapy doses [Gy], conc.: concurrent, CHT: chemotherapy, Gem: Gemcitabine, Cis: Cisplatin, 5-FU: 5-Fluorouracil, LV: Leucovorin, Ox: Oxaliplatin, Erl: Erlotinib, Cap: Capecitabine, FA: Folinic Acid, Mito: Mitomycin C, Cet: Cetuximab.
Regular follow up visits took place either at our institution or at the referring center, including at least clinical examination and abdominal CT scans every three months for the first year after treatment. In case of Ca 19-9 increase or clinical evidence for local re-recurrence or distant spread, additional tests or imaging modalities were performed to confirm or exclude disease progression at the discretion of the treating physician. Acute toxicity was scored according to CTCAE V3.0, late toxicity was scored according to RTOG criteria. In case of missing follow-up examinations, data was completed by calling the patient or the treating physician. Time to event data was calculated from the first day of radiation treatment until the last follow up information or until death. Local control was defined as absence of tumor regrowth in the region of the treated recurrence on repeated CT or MRI scans. Local control (LC), Progression-free-survival and Overall Survival (OS) were calculated using the Kaplan-Meier method. In patients without further assessment of local control e.g. after development of distant spread, the date of the last information about the local status was used for calculation Differences in subgroups were tested for statistical significance by the log rank test. Differences were considered statistically significant for a p-value of ≤0.05.
The study is in compliance with the Declaration of Helsinki (Sixth Revision, 2008). Furthermore our study was approved by the Independent Ethics Committee of the Medical Faculty Heidelberg (ref. nr.: S-491/2010).
The median follow up for the entire cohort was 16 months and 23 months in surviving patients. Considering surgery, the gross total resection rate for the entire cohort was 50%. Of the 11 patients receiving neoadjuvant chemoradiation, gross total resection was achieved in 7 patients (64%). Of the 25 patients scheduled for upfront surgery, gross complete resection was achieved in 11 patients (44%), whereas 6 patients suffered from localized macroscopic residual disease (R2-situation) and in 6 patients no resection was possible at all. The difference in gross total resection rate after neoadjuvant treatment compared to upfront surgery was not statistically significant.
Local recurrence/progression was observed in 6 patients (17%) after a median time of 17 months (range 7-25 months). The resulting estimated 1- and 2-year local control rates were 91% and 67%, respectively (Figure 2). Local recurrence was isolated in one patient, followed by subsequent distant failure in one patient and accompanied by synchroneous distant failure in 4 patients. All patients with a local re-recurrence have died, except one with an isolated local recurrence who remained stable with palliative chemotherapy until the last follow up visit. In univariate analysis, none of the tested prognostics factors (resection margin gross total vs. gross residual, schedule of EBRT neoadjuvant vs. adjuvant, age, gender, time to recurrence, adjuvant chemotherapy) had a significant impact on local control.
Distant failure was observed in 23 patients after a median time of 7 months (range 1-25 months). The first site of distant failure was liver and peritoneal space in 7 patients respectively, followed by lung in 4 patients, supraclavicular nodes in one patient and combinations of these locations in 4 patients. Overall disease progression was detected in 24 patients, resulting in an estimated median progression-free survival of 9 months. The estimated 1- and 2-year rates of progression-free survival were 40% and 26%, respectively (Figure 3). None of the tested prognostic factors ((resection margin gross total vs. gross residual, schedule of EBRT neoadjuvant vs. adjuvant, age, gender, time to recurrence, adjuvant chemotherapy) showed a significant impact on progression-free survival in univariate analysis, however a trend to improved progression-free survival was observed in female patients (p = 0.058).
Considering overall survival, a total of 22 deaths have been observed. The estimated median overall survival for the entire cohort was 19 months. The estimated 1- and 2-year rates of overall survival were 66% and 45%, respectively (Figure 4). Notably, 6 of the 36 (17%) patients lived for more than 3 years. At univariate analysis, none of the tested prognostic factors (resection margin gross total vs. gross residual, schedule of EBRT neoadjuvant vs. adjuvant, age, gender, time to recurrence, adjuvant chemotherapy) showed a significant influence on overall survival.
Severe postoperative complications were observed in three patients (8%). Two patients developed intraabdominal abscess formations which resolved after re-intervention. One patient developed a perforating gastric ulcer 10 days after surgery followed by hemorrhagic peritonitis and consequently died after multiple surgical revisions, accounting for a 90-day mortality rate of 3% for the entire cohort. Minor postoperative complications, mainly wound healing disturbances and infections, were seen in 6 patients. No acute or late side effects directly related to IORT were found. Accurate data on acute toxicity during external beam radiotherapy was available in 24 of the 31 patients including complete blood cell counts for the whole treatment time in 20 of them. A total of 8 grade 3 toxicities were observed in 6 patients, mainly as gastrointestinal (nausea, vomiting, diarrhea) and hematologic side effects (see Table 3). Considering late toxicity we found severe gastrointestinal side effects in terms of diarrhea and abdominal spasms in two patients.
Pancreatic cancer remains one of the diseases with the worst prognosis in oncology . According to stage at presentation, patients are usually divided into three groups: resectable disease (~20%), locally advanced disease (~40%) and metastatic disease (~40%) . Even in the most favourable group of patients with resectable cancer, the 5-year overall survival is limited to about 20% , and the vast majority of these patients still develops an incurable treatment failure, mainly distant metastasis. However, in 10-35% of the patients an isolated local recurrence without evidence for distant spread occurs [4, 5]. Although an isolated local recurrence represents a potentially curable situation, little interest has been paid to specifically address this situation, no generally accepted standard treatment exists, and a special follow-up for patients after resection of pancreatic cancer is not recommended by international guidelines. Consequently these patients are treated within a variety of concepts initially developed for different stages of primary pancreatic cancer, ranging from aggressive surgical approaches as in primary resectable disease stages or chemoradiation as in locally advanced pancreatic cancer to palliative chemotherapy as in metastatic situations. However, there are some arguments for addressing this situation as a specific stage of disease. In our cohort, the median time to local recurrence from primary treatment was 20 months. In contrast to primary resectable pancreatic cancer, these patients did obviously not develop early distant metastasis, which is a common feature after curative intended surgery. For example, in the Conco-001 trial , which addressed the issue of adjuvant chemotherapy in resectable primary pancreatic cancer, the median disease-free survival in the experimental arm was only 13 months, mainly due to early distant failure, while local recurrence was observed only in about 20% of the patients. In contrast to metastatic disease, these patients could rationally benefit from a local treatment component as they suffer from a locoregional confined situation. Although they share some features with LAPC patients like aggressive local invasion into adjacent structures, they differ to some extent from this patient group as they have already been exposed to surgery and frequently chemotherapy. Therefore, it seems reasonable to assume (at least to some extend) a different disease biology in these patients, and to specifically address this situation as a unique stage of disease.
To our knowledge, our cohort represents one of the largest series published in peer reviewed literature that specifically addresses the treatment and outcome for isolated local recurrences of pancreatic cancer. With our treatment approach which includes radical surgery, IORT and chemoradiation, we observed encouraging rates of local control, disease-free survival and overall survival with acceptable toxicity. Notably, 6 of our 36 patients lived for more than 3 years and the estimated median survival of 19 months after the treatment of local recurrence found in our analysis compares favourable with the results published by other groups addressing LAPC (which seems to be the best available benchmark in the absence of randomized trials or larger cohort series specifically addressing isolated local recurrences). Using chemotherapy alone, modern phase III trials consistently reported median overall survival rates of only 9 to 10 months [8–10] for LAPC and about 6 to 8 months for metastatic disease [10–12]. The evaluation of chemoradiation approaches within modern phase II and III trials resulted in improved locoregional control rates but only in slightly improved median overall survival rates of 11 to 12 months [8, 13–15], although some single center studies reported median overall survival rates of 17-19 months due to intensification of treatment [16–18].
Similar to primary pancreatic cancer, long term survival is hardly imaginable in patients with isolated local recurrences without the achievement of locoregional control. But even in resectable primary pancreatic cancer, local recurrences occur in up to 75% of the patients based on autopsy findings due to the always narrow and often positive margins . Adjuvant chemoradiation using fractionated external beam radiation therapy (EBRT) has proven to reduce local recurrence rates compared to chemotherapy alone regardless of its conflictingly reported influence on overall survival . However, the dose that can be safely applied with external beam radiotherapy is limited due to the tolerance of surrounding structures at risk, mainly small bowel. Even with the use of intensity-modulated therapy (IMRT), doses beyond 60 Gy, which are potentially needed to sterilize at least microscopic residual disease , can hardly be achieved without unacceptable toxicity. Especially surrounding bowel structures cannot be adaequately spared due to the narrow anatomical relations and the intra- and interfractional movements. Therefore, other radiation techniques, namely stereotactic radiosurgery (RS) and intraoperative radiation therapy (IORT) have been investigated as sole treatment or as boost techniques in combination with EBRT to achieve further dose escalation in LAPC. Notably, most of these trials also included small numbers of isolated local recurrences, but subgroup analyses were not available [21–23]. In the initial experience with RS published by the Stanford group, RS resulted in excellent short term local control rates (80-100%), but did not improve median survival (median OS 8-11 months) compared to fractionated chemoradiation and raised some concerns about late toxicity of high single doses in the pancreatic region [21, 22]. However, Mahadevan et al.  recently reported a series of 36 patients with unresectable pancreatic cancer treated with 3 fractions of stereotactic radiotherapy up to total doses of 24-36 Gy followed by gemcitabine using an adaptive tolerance-based dose prescription approach dependent on the distance of the target to duodenal structures. After a median follow-up of 24 months, a local control rate of 78% with a median disease-free survival of 9 and a median overall survival of 14 months was found .
In our study, we observed comparable results (local control 83%) using intraoperative radiation therapy (IORT) as a boosting strategy in combination with maximal surgery and moderate doses of external beam radiotherapy to overcome the dose limitations mentioned above. In contrast to all external radiation therapy techniques, IORT enables the unique opportunity of displacing organs at risk from the irradiation field by simple removal during the surgical intervention. Further on, the target area is defined and treated under visual control, which minimizes the risk of a geographic miss and no additional safety margins are needed to compensate for interfraction movements. Although the applicability of the linear-quadratic model for high single doses as used in IORT has been questioned to some extend , it can be assumed from clinical and experimental data that a combination of 15 Gy IORT boost with 45 Gy EBRT dose as used in our study is biologically equivalent to ≥70 Gy EBRT in conventional fractionation . The translation of dose escalation into improved local control found in our study has also been reported by other investigators using IORT in locally advanced unresectable pancreatic cancer: For example, Garton et al.  found 1- and 2-year local control rates of 86% and 68% and a median overall survival of 15 months in a series of 51 patients with unresectable pancreatic cancer treated with neoadjuvant EBRT followed by IORT. Roldan et al  compared patients with locally advanced pancreatic cancer scheduled either for IORT + EBRT or EBRT alone and observed a significant advantage in local control in favour of the IORT group. Mohiuddin et al.  found a local control rate of 69% with a median overall survival of 16 months in 49 patients with unresectable pancreatic cancer treated by IORT and postoperative chemoradiation followed by maintenance chemotherapy. Moreover, Willett et al.  reported a median survival of 13 months in a large series of 150 patients with unresectable pancreatic cancer treated with a combination of IORT and EBRT. These and our results compare favourable with approaches of chemoradiation or chemotherapy alone in terms of local control and strengthen the value of locally controlled disease for overall survival as supported by a recent pooled analysis on behalf of the International Society of Intraoperative Radiation Therapy (ISIORT) in Europe . This described a prolonged survival in resectable pancreatic cancer patients who remained free of local recurrence for more than two years after surgery and IORT (5-years OS 28%) compared to those who failed locally (5-year OS 0%).
However, beside the encouraging local control rate found in our series, distant failure occurred in the majority of patients. In contrast to primary pancreatic cancer, the value of adjuvant chemotherapy after resection of a local recurrence or the use of additional chemotherapy after chemoradiation has not been clearly established. Therefore, only a minority of our patients received additional chemotherapy directly after completion of local treatment at the discretion of the treating medical oncologist. Given the known advantages of adjuvant chemotherapy in terms of disease-free and overall survival after gross total resection of primary pancreatic cancer , additional adjuvant systemic therapy might be beneficial also after local treatment of an isolated local recurrence. This should be evaluated, although a recent retrospective analysis by Baschnagel et al.  failed to show a benefit from additional systemic therapy after postoperative chemoradiation in primary pancreatic cancer cases. The possible value of additional systemic therapy seems to be further supported by the fact, that those studies which report encouraging results with chemoradiation for locally advanced pancreatic cancer, additional or maintenance chemotherapy was used after completion of local therapy [13, 15].
Another issue in pancreatic cancer is treatment toxicity. In our study, we observed a 90-day postoperative mortality rate of 3% (1 patient). Severe postoperative complications were found in 8% of the patients. Acute gastrointestinal (GI) grade III toxicities attributable to chemoradiation were observed in 10% and grade III hematological toxicities in 20% of the evaluable patients. No severe IORT related toxicity was found. These figures compare favorable with data from the literature. Calvo et al.  reported 33% grade III GI-toxicity and 6% severe hematological toxicity with neoadjuvant chemoradiation + IORT. Aristu et al.  observed 12% severe gastrointestinal and 16% hematological toxicity during neoadjuvant chemoradiation followed by IORT in unresectable cases. IORT can be safely applied in patients with pancreatic cancer without an increase of postoperative morbidity or mortality compared to surgery alone as shown by Reni et al.  in a comparative series of 203 patients. Considering toxicity of external beam chemoradiation, it has to be emphasized, that severe toxicity is closely associated with the radiation technique and the irradiated volume. If modern radiation techniques are used, and the radiation fields are restricted to the gross tumor volume with small safety margins, the incidence of severe GI-toxicity appears to be much lower than in previous trials using elective nodal irradiation as well. A recent EORTC trial comparing chemotherapy with gemcitabine mono versus concurrent chemoradiation with gemcitabine in the adjuvant setting of pancreatic cancer observed no significant difference in toxicity between the treatment arms .
In summary, to our knowledge this analysis represents the largest series published in peer-reviewed literature dealing exclusively with the treatment and outcome of isolated local recurrences of pancreatic cancer using IORT. Given the retrospective nature of our study, conclusions should be drawn with caution. However, aggressive local treatment including surgery, IORT and chemoradiation resulted in encouraging local control, median overall survival and a substantial proportion of long term survivors in our cohort with acceptable toxicity. Given the high rates of distant failure, the use of additional systemic therapy after completion of local treatment should be discussed. Nevertheless, the results with our treatment approach seem to be superior to palliative chemotherapy or chemoradiation alone and should be further tested in a prospective setting specifically addressing isolated local recurrences of pancreatic cancer.
FR planned the analysis, participated in data acquisition, data analysis, literature review, patient treatment, and drafted the manuscript. CT, MU, GH, FWH, RK, PH, MWB participated in data aquisition, data analysis, literature review and patient treatment. JD and JW participated in planning of the analysis, patient treatment, manuscript draft and revised the manuscript critically. All authors read and approved the final manuscript.


Should the RRSP Home Buyers' Plan (HBP) be expanded and modernized? That's what the Canadian Real Estate Association (CREA) is proposing. CREA has put forward a number of proposals, the biggest of which is "intergenerational RRSP loans" to help first-time homebuyers.
At first glance this seems like a good idea. Home prices are rising fast in big cities like Toronto and Vancouver, requiring larger down payments, so why not throw more money at the problem? Unfortunately, this proposed change could do more harm than good. Let's take a closer look.
Nearly one in five first-time homebuyers are already getting financial help from a family member with their down payment, finds an online survey by CMHC. With rapidly rising home prices in major cities across Canada, the increase in adult children making withdrawals from the Bank of Mom and Dad should come as no surprise. So are intergenerational RRSP loans the solution?
On the surface, intergenerational RRSP loans look like a good idea. All the points CREA and TREB have made are valid, but there are several key flaws they conveniently left out.
Intergenerational RRSP loans would tend to favour the rich. Children of wealthy parents would have a distinct advantage over parents who can't afford to gift their adult children their down payment funds. I don't know about you, but my parents aren't in the financial position to gift me money toward a down payment for a home and I'm not alone. Many parents aren't.
And for the parents that do gift their kids money, some of that money's not even coming from savings. Some parents are tapping into the equity of their homes to gift their adult children the money. While I'm all for helping your adult child when possible, putting your financial wellbeing in danger, especially when your child's peak earnings years are ahead of them, makes absolutely no sense.
Letting parents use their RRSP funds to loan to their children to buy a first home is a slippery slope. The RRSP should be used as it was intended: for retirement savings. The facts speak for themselves. Only about a third of Canadians have a workplace pension plan. With people living longer than ever before, combined with the perpetually low interest rate environment, our parents will likely need every penny in retirement.
And then there are those darn "unintended consequences." Although intergenerational RRSP loans may help some first-time homebuyers in the short-term, they're likely to push up home prices in the long-term for everyone. This helps homeowners and real estate agents, but not so much home buyers.
There's no silver bullet to fixing the rising home price phenomenon. But the sooner governments realizes that, the sooner they can start addressing the housing supply mismatch in big cities.


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You are here: Home \ Module B \ B3 Controls on the Management of Contained Waste \ B3.8	UK Policies and Controls \ B3.8.1	UK Wide \ B3.8.1 UK Wide continued (2)
B3.8.1 UK Wide continued (2)
Waste and Emissions Trading Act 2003
Part 1 of the Act provides for:
the setting of the maximum amount of biodegradable municipal waste which is allowed to be sent to landfills from each country of the UK;
the allocation of landfill allowances, which may be tradable, to waste disposal authorities;
the preparation, in each country of the UK, of a strategy for reducing the amount of biodegradable waste going to landfills;
the National Assembly of Wales to make regulations requiring local authorities in Wales to have municipal waste management strategies and provide information about waste;
an amendment to the Environmental Protection Act 1990 to allow waste disposal authorities to direct waste collection authorities about the separation of waste;
the waste authorities for each two-tier area of England, subject to certain exemptions, to draw up joint municipal waste management strategies.
the development of the statutory framework for wider emission trading by amending the Pollution Prevention and Control Act 1999 to include the power to provide penalties (including automatic financial penalties) for non-compliance with future schemes;
the enforceability of penalties for non-compliance with the current UK Emissions Trading Scheme (including automatic financial penalties).
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The album features influences of synthpop and bubblegum pop and was met with generally positive reviews from music critics. Although Jon Carmichael of The New York Times found Lovato's transition fun, according to Entertainment Weekly it signified a less-mature image. The album debuted at https://alphadeltatravel.com/the-secret-life-of-costa-rica-girls/ number three in the US, with first-week sales of 110,000 copies, the best-selling debut week of Lovato's discography. It was also successful internationally, charting in the top ten in New Zealand, Spain and the UK. Lovato released her third studio album, Unbroken, on September 20, 2011.
A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands. It includes people who indicate their race as "Native Hawaiian", "Guamanian or Chamorro", "Samoan", and "Other Pacific Islander".
Dreaming of You became the second-highest debut that year, behind Michael Jackson. A registered nurse and fan named Yolanda Saldívar asked Selena's father to start a fan club in San Antonio, Texas. Saldívar had the idea after she had attended one of Selena's concerts.
On February 2, 2020, Lovato performed "The Star-Spangled Banner" at Super Bowl LIV. A few days later, Lovato revealed that she would host a talk show, Pillow Talk With Demi Lovato, to air on the new video streaming platform Quibi. On April 16, Lovato released a collaboration titled "I'm Ready", with English singer-songwriter Sam Smith. In June 2020, it was announced that YouTube would release a four-part documentary series following Lovato's life. The currently untitled project will be directed by Michael D. Ratner and will reportedly showcase Lovato's personal and musical journey over the past three years. A remix of "Lonely Hearts" by JoJo featuring Lovato is scheduled for release on August 28, 2020.
Many Latino families migrate to find better economic opportunities in order to send remittances back home. Being undocumented limits the possibilities of jobs that immigrants undertake and many struggle to find a stable job. Many Latinos report that companies turned them down because they do not have a Social Security number. If they are able to obtain a job, immigrants risk losing it if their employer finds out they are unable to provide proof of residency or citizenship. Many look towards agencies that do not ask for identification, but those jobs are often unreliable.
Ryan Seacrest".
Gomez appeared in the short film El Tux as Claudia Gómez and as Nina in the Discovery Channel television film La estación de la Calle Olvera . She filmed a music video as part of G.L.A.M. for a song titled "JellyBean" in 2009. During this time, Gomez also began recording herself singing and rapping songs using Garageband, and created a YouTube account to post covers of popular songs online. She also began writing her own songs, and by the age of thirteen had taught herself how to play guitar.
Over half of the Hispanic population is concentrated in the Southwest region, mostly composed of Mexican Americans. California and Texas have some of the largest populations of Mexicans and Central American Hispanics in the United States. The Northeast region is dominated by Puerto Ricans and Dominican Americans, having the highest concentrations of both in the country. In the Mid Atlantic region, centered on the DC Metro Area, Salvadoran Americans are the largest of Hispanic groups. In both the Great Lakes States and the South Atlantic States, Mexicans and Puerto Ricans dominate.
The term Hispanic derives from Latin Hispanicus, the adjectival derivation of Latin Hispania , ultimately probably of Celtiberian origin.
The Spanish language is the main cultural element shared by Hispanic peoples.
Some famous Hispani and Hispaniensis were the emperors Trajan, Marcus Aurelius, Hadrian, Theodosius I and Magnus Maximus, the poets Marcus Annaeus Lucanus, Martial and Prudentius, the philosophers Seneca the Elder and Seneca the Younger, and the usurper Maximus of Hispania.
The Hispano-Romans were composed of people from many different indigenous tribes, in addition to Italian colonists.
A number of these men, such as Trajan, Hadrian and others, were in fact descended from Roman colonial families.
Moreover, Latinos' immigration/nativity status plays a major role regarding their academic achievement. For instance, first- and second- generation Latinos outperform their later generational counterparts. First, Hispanic students attending pre-K or kindergarten were more likely to attend full-day programs.
However, the album's lead single and last single both achieved moderate success. It was announced on July 14, 2011, that Gomez had signed a license agreement with Adrenalina, an extreme sports and adventure-themed lifestyle brand, to develop, manufacture, and distribute the actress's fragrance. Chairman and C.E.O. of Adrenalina, Ilia Lekach, said, "We are incredibly enthused to be working with Ms. Gomez and will reveal more details pertaining to the fragrance as we get closer to the launch date." The perfume was released in May 2012. The Guinness Book of World Records named Selena as the "most dominating artist".
Latinas In Tech
As the spokeswoman for the company, she filmed commercials to promote the brand and featured their products in her music videos. "Can't Stop Dancin'" was serviced as the next single from the album on November 4.
The Lenca sites of Yarumela, Los Naranjos in Honduras, and Quelepa in El Salvador, all contain evidence of the Usulután-style ceramics. Latin America, extending from the deserts of northern Mexico to the icy wilds of Tierra del Fuego in Chile and Argentina, encompasses many diverse countries and peoples. Though most of these countries are largely Catholic and Spanish-speaking, thanks to a shared history of colonization by Spain, they have at least as many differences as they do similarities with each other. In the United States the terms "Hispanic" and "Latino" (or "Latina" for a woman; sometimes written as "Latinx" to be gender-neutral) were adopted in an attempt to loosely group immigrants and their descendants who hail from this part of the world. The terms are often used interchangeably, though the words can convey slightly different connotations.
Gomez talked about being influenced by Selena and that she is proud of her Mexican heritage. Gomez was featured on Play-N-Skillz's both Spanglish and English remake versions of the song "Si Una Vez" by late Tejano singer Selena, alongside Frankie J and Kap G. The singles were released on February 24 and April 7, 2017, respectively. On February 20, 2017, Gomez teased the release of her single, "Todo Cambio", after posting a photo of herself wearing a wedding dress on social media. The song was released on March 3, 2017, and serves as the third single from her debut album.
These disparities are leaving a growing portion of our population more vulnerable to poverty and its implications. Among Hispanic Americans, country of origin also has a strong impact on labor force participation. Hispanic workers are one of the fastest-growing populations in the labor force, yet many are still held back by structural disparities and discrimination that result in low wages and other negative labor market outcomes. In addition to finding that unexplained wage gap for Hispanic women is greater than the aggregation of the absolute ethnic and gender effects, we also identify particular groups of Hispanic women at an even greater disadvantage. The media has a lot of room to grow in terms of their portrayal of non-American cultures and it can start by just having ethnic women play regular roles as common people, rather than portray a character and fill a stereotype that is completely made up by a white male's mind.
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®iPharma – Trova la farmacia che ti serve
®iPharma è un'applicazione gratuita per ®iPhone, ®iTouch e ®iPad che fa da guida completa per chi ha bisogno di una farmacia e non necessita di connessione internet e gsm attiva.
Il paziente digitando ad esempio holter pressorio, vedrà subito quali farmacie attorno a lui sono attrezzate a tale servizio, saprà a quale incaricato rivolgersi e scegliere la farmacia ove recarsi, non più per la sola vicinanza, ma anche per la facilità d'accesso e la migliore informazione!!
Installa ®iPharma direttamente dal tuo ®iPhone tramite la funzione ricerca di Apple store.
Farmacista titolare? Aggiorna online i dati della tua attivita' e fatti trovare!
NB:Il programma è in fase di sviluppo ed inizialmente rivolto agli utenti in Italia.
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