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Composer Profile: Alistair MacDonald
April 4, 2014 April 4, 2014 ~ f. d. leone
Alistair MacDonald
Website | Soundcloud
Dr. Alistair MacDonald is a composer and performer based in Glasgow. Much of his work is collaborative; working with performers, artists and choreographers from different media and backgrounds, he makes work for performance, broadcast and installation internationally.
Current projects include Strange Rainbow, a live electroacoustic duo with Scottish harp player Catriona McKay (performances include Celtic Connections, sound festival in Aberdeen and the Norwegian Film Festival) and collaboration, with Carrie Fertig, on Glimmer for glass percussion, electronics and live flame-working, recently selected for the Coburg Prize for Contemporary Glass.
Recent works include The Imagining of Things with Brass Art (video and audio installation) for Huddersfield Art Gallery and the Huddersfield Contemporary Music Festival, Mitaki (string quintet and live electronics) for the Scottish Ensemble, and a number of acousmatic works.
Interactive, performative installation Sensuous Geographies, in collaboration with Sarah Rubidge (shown in the UK and USA) was was awarded a Creative Scotland Award in 2002; Silver Wings and Golden Scales (2007), an installation in collaboration with Jennifer Angus, was commissioned for the Chazen Museum of Art in Wisconsin; SeaUnsea (2006), an interactive dance and video work with programmer Chiron Mottram, choreographer Carol Brown and architect Mette Ramsgard Thomsen was premiered at Dance Umbrella 2006 at the Siobhan Davies Studios. Other commissions include music for The Scottish Ensemble, The Paragon Ensemble, BBC Radio Scotland, Reeling and Writhing, the Australian ensemble Elision, choreographer Shobana Jeyasingh and Theatre Cryptic.
He teaches composition and directs the Electroacoustic Studios at the RCS where he was made a Fellow of the Royal Conservatoire in 2012.
…playing with the big radio in our kitchen as a small boy, turning the dial slowly and listening to the faint signals – music, but also voices, Morse code, filtered noise… mysterious sounds
– there are many other things (including my dad's reel to reel tape recorder, and our Dansette record player; the strings of the piano I strummed and scraped when I was still too small to reach the keys) and local music (my dad played Northumbrian pipes, mum played piano, singing in church).
Too many to name, and the list is constantly being added to. But not just composers – other musicians too. And artists and dancers. I'm not keen on the idea that my (or anyone's) musical ideas and identity comes only from other music & musicians – that can be quite a skewed view.
My composition teachers, Nigel Osborne, Denis Smalley, Jonty Harrison, not so much for their (excellent) music, but rather their encouragement. Simon Atkinson whose delicate investigation into texture led me to make some forays in that direction. Keith Tippett and Evan Parker, two amazing musicians who play free jazz. The first time I heard Evan literally left me speechless. Composition in real time. Iannis Xenakis – I don't know a lot of his work, but hearing Leicestershire Schools Orchestra (!) play Jonchaies similarly sent me spinning.
Catriona McKay, the clarsach player I work with. A fearless musical explorer and risk taker. One of the most creative and talented musicians in Scottish music today.
My work is split between pure electroacoustic music which exists as a finished recording; work with live electronics; and collaborative work in a number of arenas.
The pure electroacoustic/acousmatic work always starts with sounds I have recorded – things I have discovered and found to be fascinating as a starting point (see answer to Q1). There follows a period of play – the playfulness is important, it's a way of discovering the potential of the material rather than deciding strategies in advance. Then composition/assembly, with frequent digressions back into play. The whole process of composing in the studio is a performative one.
This is connected to the work with live electronics. More and more these are collaborative ventures with musicians who play their instruments better than I could write for them, and often involve aspects of improvisation either in the making and fixing of the piece, or in performance itself. In an ideal situation there's lots of to-ing and fro-ing.
Other collaborative work similarly involves lots of exchange and experiment. One of the most successful pieces, Sensuous Geographies, took a year to make, but had been a seed in the back of our minds for 15 years before that!
I use a computer. I work in Pro Tools for recording/mixing/editing/processing. Other composers use other DAWs (Digital Audio Workstation) but Pro Tools suits me (particularly the editing and management of edited clips which is a nightmare in Logic, for example). I use other bits of software to do specific processing things too.
I also use MaxMSP extensively – in the installation pieces, and in the pieces and improvisations involving live electronics. It's great – I'm not a real programmer but I can still build pretty much anything I can imagine. It's not stuck in what Trevor Wishart calls "lattice oriented" thinking. I have used it with external controllers including sensors (via Arduino), video input, faders & other MIDI devices, but I'm using the Lemur app on an iPad at the moment which I'm really enjoying.
I work when I can, but teaching and academia get in the way, so it's not a regular thing. However I'm on sabbatical at the moment so it's every day (until the end of March!)
For notation I use Noteability Pro which does proportional notation and graphics pretty well, though not much of what I do involves notation.
I record sounds with mics, but have also just started working with contact mics and hydrophones.
Please describe a recent work and provide a link to an audio clip.
Scintilla (electroacoustic music, 2013)
Scintilla – a spark, a glimmer, a particle of fire, a glittering speck.
Scintilla started life with the hand made, flame-worked, glass instruments made by Carrie Fertig for her Torcher Chamber Arkestra's performance at the British Glass Biennale in 2012. Sounds from these intriguingly shaped objects create a dense, powerful, resonant texture but at the same time hints at their fragility and vulnerability."
Carrie is a really interesting artist. She has this Torcher Chamber Arkestra, a group of flame working glass artists she got together to 'perform'. She made some glass instruments (percussion) and asked me to write for them. The result was a piece which was for 2 percussionists and electroacoustic sounds. I felt I had just scratched the surface of the material so I took it back in the studio and made Scintilla. I was interested in doing something un-percussive in contrast to the first piece, so Scintilla is more static – less about forward motion and more about a listening in to detail. The overall shape, then, is very simple, so the ear is free to listen in. And in the end the fragile sounds which are just beneath the surface are the details.
The whole performance is at, with my piece beginning at ~ 31 minutes:
Posted in Profiles acousmaticcollaborativeelectroacousticelectronicsinstallations
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Next ›Composer Profile: Felipe Otondo


Cook says that in the week after the release of iOS 6, Apple has seen more than half a billion locations in its Maps app, no doubt helped by the 100 million users that have updated their devices to run the new software.
Last week, Apple addressed the state of its Maps app, noting that it launched the service knowing that it is a 'major initiative' and that it was just getting started with it. "The more people use it, the better it will get, said Apple spokesperson Trudy Muller at the time.
However, with users finding it almost impossible to find landmarks and other locations within the app, Apple has been forced to apologise for its lack in functionality, with the company's chief executive making no excuses for its rushed launch.
With the apology out of the way, Apple will be doing all it can to improve the quality of its new service. It isn't known what the company intends to do remedy the situation, but reports have stated that Apple's maps teams are working day and night to remove erroneous data and increase its accuracy.


Greetings! I have been self-employed since 1993. Up to this point I have been funding a SEP IRA for my retirement fund. I would like to be able to put more money away but am not sure what the best route to take would be. I have heard about Keogh's and profit sharing plans. Does anyone know if they are the same thing? Can anyone explain to me in plain English how they work? Or recommend some good reading on the subject? Thanks!!


Back in the 80s, I was watching a cooking show on TV. The chef specialized in grilling foods and this is his recipe. It's one of my favorite ways to grill chicken.
Prepare marinade from all ingredients. Cut slits in chicken (with skin preferred). Cover and refrigerate for 4 or more hours. Remove chicken from marinade and grill.


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EDITORIAL: Behind Malcolm Turnbull's pitch for green votes
CANBERRA OBSERVED: The Costello question that refuses to go away
ECONOMIC AFFAIRS: China's spending spree: our sovereignty at risk
GLOBAL FINANCIAL CRISIS: Targeted spending needed to promote Australian jobs
NEW ZEALAND: Kiwibank goes from strength to strength
QUEENSLAND: Premier Bligh calls snap election
PUBLIC ACCOUNTABILITY: Shooting the messenger undermines democracy
HEALTH: Labor's campaign against doctors' private practices
UNITED STATES: The nightmarish cabinet of President Obama
FOREIGN AFFAIRS: UN whitewash of China human rights abuses
GLOBAL WAR ON TERRORISM: What to do with Guantánamo detainees?
SPECIAL FEATURE: The agnostic who took on Darwin and Dawkins
MARRIAGE AND FAMILY: Sexual suicide of Western society
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Euthanasia and dementia sufferers (letter)
Wilson Tuckey I (letter)
Wilson Tuckey II (letter)
CINEMA: Stylised miniature of feminist mythology - Revolutionary Road
BOOKS: ATTILA THE HUN: Barbarian Terror and the Fall of the Roman Empire, by Christopher Kelly
ATTILA THE HUN: Barbarian Terror and the Fall of the Roman Empire, by Christopher Kelly
by Michael Daniel (reviewer)
News Weekly, March 7, 2009
The scourge of Roman civilisation
ATTILA THE HUN:
Barbarian Terror and the Fall of the Roman Empire
by Christopher Kelly
(London: Bodley Head)
Rec. price: AUD$36.00
Attila the Hun is one of the most infamous figures of Western history. In many left-wing circles, the ultimate insult is to describe someone as "to the right of Attila the Hun".
Christopher Kelly examines not only Attila the Hun's career but also his importance in the fall of the western Roman empire. His narrative unfolds largely chronologically, commencing with the first contact the Romans had with the Huns in the late 4th century AD.
Various barbarian tribes, fleeing westward from the Hun incursions into their territories, sought sanctuary across the Danube in the 370s. Roman mistreatment of the Goths sparked a series of events which led to the battle of Adrianople in 379 in which a Roman army was not only defeated but massacred.
Gaining foothold
This battle revealed to the Goths, in particular, that the Roman empire was not as strong as they had hitherto believed. It emboldened them to gain a foothold into Roman territory. Henceforth, Rome either fought, or allied itself with, the Goths.
This battle is seen by many historians as the start of the process of the disintegration of the western Roman empire. In the succeeding decades, a combination of poor decisions and eastern Roman emperors prioritising the defence of the eastern empire at the expense of the western empire saw the gradual loss of Roman territories to the Vandals and the Goths.
The Romans had a low opinion of the various barbarian tribes, but regarded the Huns as being their most bloodthirsty adversaries. The Huns in their frequent military campaigns were willing to slaughter their victims and plunder their assets.
By the fifth century, the Huns had settled in what is now modern-day Hungary. A belligerent tribe, they came to pose a threat not only to the two Roman empires, but to the Gothic kingdoms as well.
Their most famous leader, Attila, alternated between alliances with Rome, in return for large amounts of annual tribute, and attacks on Roman territory. A negotiated peace with the Romans bought the eastern emperor Theodosius II time to reinforce the defences of Constantinople.
However, Attila's invasion of the Roman empire in 440 enabled the Vandals under Geiseric to capture northern Africa, as the empire was channelling its resources into repelling Attila.
In the following years, the Huns won a number of victories in the eastern empire; however, Attila failed to penetrate the defences of Constantinople.
Attila then turned his attentions towards the Visigothic kingdom of Toulouse. The western empire, although it initially supported such an invasion, as it would weaken one of their enemies, ended up allying itself with the Visigoths against Attila. This was because of Attila's hatred of the western emperor Valentinian III who refused to recognise a promise his sister Honoria had made to marry Attila.
A combined army of Goths and Romans defeated Attila at the Battle of the Catalaunian Plains in 451. However, the Roman commander Aetius, the de facto power-broker in the western empire since the 430s, did not capitalise on it by pursuing Attila.
He probably feared that eliminating Attila would have given the Goths greater opportunity to solidify their kingdom at Rome's expense. However, Kelly makes the point that the significance of the Roman alliance with the Visigoths was that, for the first time, Rome recognised the Visigothic kingdom, thereby diminishing Rome's chances of regaining territory that it believed had been usurped by invaders.
The following year, when Attila attacked northern Italy, the famous intervention of Pope Leo prevented further bloodshed. Attila's career of almost continual bloody campaigns ended only with his sudden death in 453. With no strong and clear successor, the Hun empire soon dissolved.
In his final chapter, Kelly argues that the Hun incursions played a significant role in the fall of the western empire. They not only depleted Rome's resources in battle but diverted Rome from repelling other barbarian tribes, particularly the Vandals and the Goths, who had seized former Roman provinces.
However, Kelly notes that by the time of Attila's demise a successful campaign by Rome against a barbarian kingdom such as that of the Visigoths would only have created a vacuum that would have enabled another barbarian group to seize that territory.
Two decades after Attila's death, the barbarians gained control of Italy, and forced the last western emperor to abdicate, no longer regarding his office as holding any significance.
Ironically, whilst the western empire was by this stage divided among barbarian kingdoms, Rome's influence was to remain, one tangible sign being the Romance languages of Spanish, French and Italian, all of which are derivatives of Latin, not Gothic or Frankish languages.
Kelly ends his assessment of Attila by observing that, while Attila's campaigns were bloody, he probably killed no more soldiers and civilians in his 30 years than Julius Caesar did in Gaul in just under 10 years.

redpajama_set_name: RedPajamaCommonCrawl


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Compare Haiti to other countries
Show the size of Haiti compared to Cambodia Hide the map
If Haiti were your home instead of Cambodia you would...
be 135.3 times more likely to be unemployed
Haiti has an unemployment rate of 40.60% while Cambodia has 0.30%
be 5.7 times more likely to be murdered
10.20 in every 100,000 people are murdered annually in Haiti compared to 1.80 in Cambodia
make 50% less money
The GDP per capita in Haiti is $1,300 while in Cambodia it is $2,600
The per capita consumption of electricity in Cambodia is 166kWh while in Haiti it is 20kWh
be 2.6 times more likely to have HIV/AIDS
The percentage of adults living with HIV/AIDS in Haiti is 2.10% while in Cambodia it is 0.80%. 7,500 people in Haiti and 2,700 people in Cambodia die from AIDS each year.
experience 56.2% more of a class divide
The GINI index measures the degree of inequality in the distribution of family income. In Haiti it is 59.20 while in Cambodia it is 37.90.
consume 44% less oil
Cambodia consumes 0.1050 gallons of oil per day per capita while Haiti consumes 0.0588
be 3.76% less likely to die in infancy
The number of deaths of infants under one year old in a given year per 1,000 live births in Haiti is 49.43 while in Cambodia it is 51.36.
spend 2.53% more money on health care
Per capita public and private health expenditures combined in Haiti are $52.60 USD while Cambodia spends $51.30 USD
be 1.02% less likely to be in prison
97 in every 100,000 people are currently imprisoned in Haiti compared to 98 in Cambodia
die 0.6 years sooner
The life expectancy at birth in Haiti is 63.18 while in Cambodia it is 63.78.
have 6.43% fewer babies
The annual number of births per 1,000 people in Haiti is 22.83 while in Cambodia it is 24.40.
More Information about Haiti
With its 9,996,731 people, Haiti is the 88th largest country in the world by population. It is the 146th largest country in the world by area with 27,750 square kilometers.
The native Taino - who inhabited the island of Hispaniola when it was discovered by Christopher COLUMBUS in 1492 - were virtually annihilated by Spanish settlers within 25 years. In the early 17th century, the French established a presence on Hispaniola. In 1697, Spain ceded to the French the western third of the island, which later became Haiti. The French colony, based on forestry and sugar-related industries, became one of the wealthiest in the Caribbean but only through the heavy importation of African slaves and considerable environmental degradation. In the late 18th century, Haiti's nearly half million slaves revolted under Toussaint L'OUVERTURE. After a prolonged struggle, Haiti became the first post-colonial black-led nation in the world, declaring its independence in 1804. Currently the poorest country in the Western Hemisphere, Haiti has experienced political instability for most of its history. After an armed rebellion led to the forced resignation and exile of President Jean-Bertrand ARISTIDE in February 2004, an interim government took office to organize new elections under the auspices of the United Nations. Continued instability and technical delays prompted repeated postponements, but Haiti inaugurated a democratically elected president and parliament in May of 2006. This was followed by contested elections in 2010 that resulted in the election of Haiti's current President, Michel MARTELLY. A massive magnitude 7.0 earthquake struck Haiti in January 2010 with an epicenter about 25 km (15 mi) west of the capital, Port-au-Prince. Estimates are that over 300,000 people were killed and some 1.5 million left homeless. The earthquake was assessed as the worst in this region over the last 200 years.
Languages spoken: French (official), Creole (official)
Reading about Haiti
Check out the recommended reading list below for great sources of information on Haiti


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text:
Sarah Ng
Dr Sarah Ng
sarah.ng@ndph.ox.ac.uk
The EMPA-KIDNEY study
MBChB, MRCP (UK)
Clinical Research Fellow
Sarah obtained her Bachelor of Medicine, Bachelor of Surgery from the University of Edinburgh in 2011. She completed her foundation training in Oxford and moved to the North West to take up an NIHR Academic Clinical Fellowship post, where she completed her MRCP and a Post-Graduate Certificate in Global Health from the University of Edinburgh. She commenced dual specialty training in Nephrology and Intensive Care Medicine in 2015. She sits on the Faculty of Intensive Care Medicine e-Portfolio sub-committee and is also Focussed Intensive Care Echocardiography (FICE) accredited. She is currently working as a clinical research fellow on the EMPA-KIDNEY trial.
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group None., (2021), Lancet, 397, 1637 - 1645
Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group None., (2021), Lancet, 397, 605 - 612
Haemodialysis, blood pressure and risk: at the limit of non-randomized evidence.
Ng SYA. et al, (2020), Nephrol Dial Transplant
In type 2 diabetes, SGLT-2 inhibitors reduce risk for major kidney outcomes.
Ai Ng SY. et al, (2020), Ann Intern Med, 172


text:
Books.ch
Buch.ch
Buchhaus.ch
The Poems of Catullus: Selected and Prepared for the Use of Schools and Colleges
Gaius Valerius Catullus
Creative Media Partners, LLC, 18.08.2017
Thought to have been born in or near Verona, Italy, in 84 B.C., Gaius Valerius Catullus came from significant wealth and connections. Motivated by his older brother, Catullus started writing poetry as a young boy. The genuine extant works of Catullus consists of 113 poems on a variety of subjects composed in different styles and meters. Catullus was capable of writing some of the most polished and enchanting poems. His relationship with a married woman was interwoven in many of his love poems with the creation of a character named Lesbia. Nowadays, Catullus's love poetry is considered among the best and most influential. Catullus's poems were widely appreciated by other poets. He greatly influenced poets such as Ovid, Horace, and Virgil. After his rediscovery in the late Middle Ages, Catullus again found admirers. His explicit writing style has shocked many readers. Catullus probably died in 54 B.C. at the age of 30.
Titel The Poems of Catullus: Selected and Prepared for the Use of Schools and Colleges
Autor/in Gaius Valerius Catullus
Verlag Creative Media Partners, LLC, 2017


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Home/Kenya Economy/Kenya: New ways to facilitate truck movement in and out of the port of Mombasa
Kenya: New ways to facilitate truck movement in and out of the port of Mombasa
Sonia Martinez December 1, 2021	Kenya Economy Comments Off on Kenya: New ways to facilitate truck movement in and out of the port of Mombasa 7 Views
Movement around the port of Mombasa will improve after the opening of two major roads connecting the port to the Northern Corridor transport route.
The streets Nyerere-Mbaraki and Kipevu are major arteries to and from the port.
The Nyerere-Mbaraki road was funded by the UK government, the Danish International Development Agency (Danida) and Mombasa County.
Kipevu Road was funded by the Kenya Ports Authority and the UK Government through TradeMark East Africa (TMEA).
On Tuesday, UK High Commissioner Jane Marriott met with Mombasa Governor Hassan Joho, Chief Secretary of the East African Community, Kevit Desai, and KPA Executive Director John Mwangemi to open the street they said they were the Will boost business around the port.
The Sh2.04 billion road will reduce the time it takes a driver through Gate 18/20 from six days to 30 minutes.
Once completed, the Nyerere-Mbaraki road, which cost 403 million Swiss francs, will reduce the transit time for trucks to the port from eight hours to less than four hours.
The two roads are expected to improve connectivity, thereby improving the efficiency and seamless transport of cargo from the port through the northern corridor.
Mr Mwangemi said the expanded Kipevu Street will be a big boost for the port as it has been widened to provide a seamless connection and facilitate the flow of traffic in and out of the port.
"KPA is committed to working with all stakeholders, industry players and partners on the port's modernization and capacity expansion projects," he said.
He said the project aimed to reduce the pressure from truck queues in shipyards and reduce the average time it takes for cargo to move through the port, which would boost business.
Ms. Marriott reassured Kenya of the UK Government's commitment to boost trade across the port and across the country.
She said the UK has been supporting vital physical infrastructure and the provision of services in and around the port since 2011.
"The Mbaraki Strait is transformative. It will change lives, rejuvenate the economy and create jobs, "said Ms. Marriot.
The projects will not only increase trade opportunities in Kenya and abroad, but will also help Kenyan firms take advantage of the UK-Kenyan economic partnership agreement.
"We are discussing how we can improve business opportunities and increase efficiency in Mombasa," said Governor Joho.
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"As a port city, our greatest achievement in the port business is efficiency and lead times. We want companies to work around the clock, which creates jobs."
Frank Matsaert, TMEA's Chief Executive Officer, reassured Kenya of its commitment to improving the trading environment.
By the end of 2020, TMEA had Sh 10 billion in the port. invested to support infrastructure development, the introduction of advanced systems and security reforms to reduce greenhouse gas emissions.
The port of Mombasa is the gateway to East Africa and connects Kenya with the member states of the East African Community.
The Shimanzi and Mbaraki areas are home to oil terminals and clinker and grain handling facilities that carry heavy trucks, creating traffic jams and making traffic in and out of the area to the north corridor, north coast, and south coast difficult.
Kenya Transporters Association (KTA) Northern Corridor director David Obiero praised the commissioning of Kipevu Road and said it would ease traffic pressure on trucks leaving Mombasa port via Changamwe Cross.
"It's the preferred route for truckers and is a big boost. Gate 18 was the main exit gate for trucks leaving the port for cargo to use the cargo weight before reaching the main scale from Mariakani, "said Mr Obiero.
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redpajama_set_name: RedPajamaGithub


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Termite is also a very big concern to the local residents in Selangor. One of the major factors is because most of residential housing projects in Selangor are development in areas that used to be rubber and oil palm plantations which are ideal neating sites for termites.
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But termites aren't our only issue! We have a wide range of services for pests such as bed bugs, rats, cockroaches, ants, and everything else that bothers us across Selangor.


We throw the spotlight on our great Australian landscape, with commercial landscaping services including earthworks, concreting, paving and kerbing, stonework, turfing and planting and finish off with features such as street furniture, sculptures and signage.
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We also design and construct high-end landscapes for residential and private homes throughout the Geelong region. Find out more about domestic landscape services from our partner company, King's Landscaping Design & Construction.
King's Landscaping Group is just that; a group of passionate people each with our own area of expertise. We work closely together on every landscape project and give each client our full commitment and resources.
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Well-known for producing Geelong's most sophisticated landscapes, our commercial landscape services have state-wide presence, extending into Melbourne and regional Victoria.


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About the University of Calgary
University of Calgary Calendar 2016-2017 COURSES OF INSTRUCTION Course Descriptions M Music MUSI
MUSI 101 102 103 104 127 201 203 209 211 213 221 223 225 231 233 301 302 303 304 305 309 311 313 321 323 325 327 329 331 333 341 343 351 355 401 402 403 405 415 417 421 423 427 429 441 443 445 447 451 453 462 511 513 521 523 525 527 531 533 535 551 560 561 562 611 613 615 621 623 625 629 631 633 637 641 645 651 653 661 711 733 741 751 753 761
Instruction offered by members of Music in the School of Creative and Performing Arts in the Faculty of Arts.
Music majors may count no more than 6 units (1.0 full-course equivalent) from Music 201, 301, 302, 304, 305, 401, 402 and 405 as Open Options toward their degree. Minors in Music may count no more than 6 units (1.0 full-course equivalent) from Music 201, 301, 302, 304, 305, 401, 402 and 405 for credit to their degree.
Music 101 Music Listening I
Course Hours: 0 units; H(0-2)
Also known as: (formerly Music Performance 101)
NOT INCLUDED IN GPA
Music 102 Music Listening II
Music 103 Music Listening III
Music 104 Music Listening IV
Notes: The above activity courses offer practical experience in music listening and are only open to BMus, BA (Music) and BA Honours (Music) students. Only one course is offered per year. Credit for four courses is required for graduation.
Music 127 Class Piano
Functional approach to the piano.
Prerequisite(s): Admission to a BMus program.
Notes: May not be used for credit towards any degree program.
Junior Courses
Music 201 Music Past and Present
Directed listening to and study of important music of the past and present. Content may vary from year to year. Intended for non-majors.
Also known as: (formerly Music History and Literature 209)
Music 203 Jazz History
Directed listening and analysis of jazz forms from the early beginnings of jazz to the present. Styles examined range from Early Jazz to Jazz-Rock Fusion. Major figures considered include: Louis Armstrong, Duke Ellington, Count Basie, Lester Young, Charlie Parker, Miles Davis and John Coltrane.
Notes: Music Majors and Minors may use this course for credit towards their programs.
Music 209 Introduction to Music Theory for Non-Majors
Introduction to the materials of music through development of both aural and written skills.
Notes: Open to all students. Not available for credit toward BMus, BA (Music) and Music Minor programs.
Also known as: (formerly Music Theory and Composition 209)
Music 211 Materials of Music
Investigation of the fundamental processes of music through analytical and written exercises.
Prerequisite(s): Successful completion of the Music Theory Diagnostic exam.
Notes: The diagnostic exam is given in March and during the Fall Block Week each year. Contact the School of Creative and Performing Arts for more information.
Music 213 Diatonic Harmony
Part-writing and analysis with an emphasis on diatonic harmony and modulation in the music of the eighteenth century.
Prerequisite(s): Music 211 or Music Theory and Composition 201.
Music 221 Performance Practicum I
Applied instruction in instrument or voice.
Prerequisite(s): Admission to the BMus program.
Notes: Students not admitted to the BMus program may register with an audition and consent of the Division Chair, Music.
Music 223 Performance Practicum II
Continuation of applied instruction in instrument or voice.
Prerequisite(s): Music 221 or Music Performance 291 and admission to the BMus program.
Notes: Students not admitted to a BMus program may register with an audition and consent of the Division Chair, Music.
Music 225 Musicianship I
Development of skills in rhythm, intonation and sight-singing. Performance of two-part contrapuntal exercises with diatonic modulation.
Prerequisite(s): Admission to the Music major or minor.
Notes: Students not admitted to a Music major or minor may register by audition and consent of the Division Chair, Music. This course meets for three hours per week during the Fall and Winter Terms.
Music 231 Medieval and Renaissance Music
Music from antiquity to 1600.
Notes: Students not admitted to the Music major or minor may register by audition and consent of the Division Chair, Music.
Music 233 Baroque Music
Music from 1600 to 1750.
Prerequisite(s): Music 231 or Music History and Literature 201.
Senior Courses
Music 301 Music and Popular Culture
Survey and specific examination of popular music and culture, ranging from classical styles to rock, within an historical and sociological context. The course will examine the meaning and messages of popular music, and its impact on present-day culture. Topics may include The Beatles and Rolling Stones, Rock and Roll, Black Music, jazz, music and media, blues, Sinatra, Broadway and others.
Music 302 Music in Popular Culture: Performers
Study of the impact of performers on the history of commercial music, focusing on selected performers such as The Beatles, Rolling Stones, Led Zeppelin, James Brown or Jimi Hendrix.
Music 303 World Music
Detailed ethno-musicological examination of non-western traditions.
Notes: Music Majors and Minors may use this course for credit toward their programs.
Also known as: (formerly Music History and Literature 309.28)
Music 304 Music in Popular Culture: Musical Theatre
Study of music and its relation to popular theatre (operetta and/or musicals) in a historical context through the examination of selected works and their relation to popular culture, popular song and/or jazz.
Notes: The Spring Intersession offering of this course is normally a travel-study course.
Music 305 Composers and Musical Cultures
In-depth study of selected composers, their music, and their relationship to intellectual history (i.e. Mozart and the French Revolution), and/or examinations of specific western and non-western musical cultures (i.e. Music in India, Music in post-war Germany) and their impact. Attendance at relevant musical concerts and lectures may be required.
Music 309 The Art of Music Listening
An introduction to the sensuous and structural elements of music, leading to a greater appreciation for the art of music in a global multi-cultural context.
Notes: Music Majors and Minors (except Sonic Arts Minors) may not use the course for credit towards their programs.
Music 311 Chromatic Harmony
Part-writing and analysis with an emphasis on chromatic harmony and modulation in the music of the nineteenth century.
Music 313 Materials of Twentieth Century Music
Compositional and analytical approaches to post-tonal music from the twentieth century to the present.
Music 321 Performance Practicum III
Continuation of Music 223.
Prerequisite(s): Music 223 or Music Performance 293 and admission to the BMus program. Students not admitted to a BMus program may register with an audition and consent of the Division Chair, Music.
Music 323 Performance Practicum IV
Music 325 Musicianship II
Further development of skills in rhythm, intonation and sight-singing. Performance of two-part contrapuntal exercises with chromatic modulation. Introduction to atonal exercises.
Notes: This course meets for three hours per week during the Fall and Winter Terms.
Music 327 Second Instrument Study
Applied instruction on second instrument or voice.
327.01 Second Instrument Study I
327.02 Second Instrument Study II
327.03 Second Instrument Study III
327.04 Second Instrument Study IV
327.05 Second Instrument Study V
327.06 Second Instrument Study VI
327.07 Second Instrument Study VII
327.08 Second Instrument Study VIII
Prerequisite(s): Open to Music Majors with consent of the Division Chair, Music.
Music 329 Jazz Musicianship
Musicianship in the jazz idiom, stressing the aural perception of jazz scales and modes, seventh-chord and harmonic extensions, common jazz progressions and jazz rhythms.
Notes: Open to both Music Majors and Minors.
Music 331 Classical and Romantic Music
Music 333 Late Romantic and Modern Music
Music from 1870 to the present.
Music 341 Composition I
Basic compositional techniques, and study of selected twentieth century compositions.
Music 343 Composition II
Music 351 Sonic Arts
An introduction to the creative use of computers and digital media in sonic arts.
Music 355 Sound Recording
An introduction to the practice and theory of sound and music recording.
Music 401 Music and the Humanities
Study of the interrelationship of music and the humanities in a broad cultural and historical framework. Content may vary from year to year. Intended for non-majors.
Music 402 Topics in Popular Music
Selected topics examining commercial music from a critical perspective. Topics may include the examination of the work of specific creators or performers, the recording industry, the impact of specific instruments (guitar, percussion, electronic media, etc.), or cross-cultural influences.
Music 403 Topics in World Music
Selected topics examining World Music from an historical, sociological, analytical or performative perspective. Topics may include the study of a particular musical tradition and repertoire or the study of an instrument or performance practice that appears among many traditions (for example, hand-drumming).
Music 405 Topics in Musical Culture
Selected topics examining the relationship between composers and or performers and a musical culture, focusing on repertoire (for example piano music, art song, or orchestral music of a specific era), aesthetic or technical approach (such as sonic arts or improvisation), or artistic milieu (such as fin de siècle Paris or post-1960's Montréal).
Music 415 Form and Analysis
Investigations into hierarchical relations in music. Study of how various levels of musical structure relate in order to form a whole.
Music 417 Advanced Harmonic Analysis
Investigation of the expanded harmonic resources and analytical systems used by composers from the late nineteenth century to the present.
Music 421 Performance Practicum V
Prerequisite(s): Music 323 or Music Performance 393 and admission to the BMus (Composition, Music History and Theory, or Integrated Studies) program. Students not admitted to the stated BMus programs may register with an audition and consent of the Division Chair, Music.
Music 423 Performance Practicum VI
Music 427 Professional Seminar in Music Performance I
Practical experience in music performance in a team teaching master class format.
Course Hours: 3 units; H(4S-0)
Prerequisite(s): Music 323 or Music Performance 393, and admission to the BMus (Performance) program.
Corequisite(s): Music 462.
Notes: This course meets for two hours per week during the Fall and Winter Terms.
Music 429 Topics in Jazz Improvisation
Topics in jazz improvisation, stressing improvisational tools, melody, rhythm, and ear development for the blues progression.
Prerequisite(s): Music 211 or Music Theory and Composition 201 and admission to the music major or minor.
Music 441 Composition III
Advanced creative work with an emphasis upon either chamber music composition or studio composition. Individual instruction and group seminars.
Prerequisite(s): Music 343 or Music Theory and Composition 393 and consent of the Division Chair, Music.
Music 443 Composition IV
Continuation of Music 441. Individual instruction and group seminars.
Music 445 Counterpoint
Practical study of contrapuntal technique, including species counterpoint and eighteenth century counterpoint.
Music 447 Orchestration
Practical study of instrumentation and scoring, including orchestral and wind ensemble textures.
Music 451 Electroacoustic Music
Practical study of electroacoustic and computer music with an emphasis on creative work in the medium.
Music 453 Computer Applications in Music
Use of computers in music composition, performance, education and interdisciplinary media.
Music 462 Junior Performance Project
Applied instruction in instrument or voice in connection with junior recital.
Course Hours: 6 units; F(1-4)
Prerequisite(s): Admission to the BMus (Performance) program.
Music 511 Selected Topics in Theory and Composition
Advanced topics in music theory and composition selected from such subjects as: analysis of tonal or post-tonal music, rhythmic analysis, acoustics, critical approaches to music theory, electroacoustic music, orchestration, counterpoint and fugue.
Prerequisite(s): One of Music 415, 417, 445, 447, 451 or one of Music Theory and Composition 471, 473, 475, 477, 479.
Music 513 Seminar in Theory and Composition
Creative and analytic approaches to the study of selected repertoire with an emphasis upon contemporary music.
Prerequisite(s): One of Music 415, 417, 445, 447, 451 or one 400-level Music Theory and Composition course.
Music 521 Performance Practicum VII
Music 523 Performance Practicum VIII
Music 525 Topics in Music Performance
Various topics such as applied music literature, piano, wind or string pedagogy, or vocal pedagogy, phonetics.
Prerequisite(s): Admission to the BMus or BA(Music) Program and consent of the Division Chair, Music.
Music 527 Professional Seminar in Music Performance II
Music 531 Research Techniques and Bibliography of Music
Exploring the basic reference materials and techniques for musical research in all areas.
Music 533 Selected Topics in Musicology
A specific musical medium or genre: may include chamber music literature, symphonic literature, dramatic literature and program music.
Music 535 Studies in the Music of Selected Composers
Specific composers or groups of composers; may include Beethoven, Debussy, the Second Viennese School, etc.
Music 551 Networked Music Performance
Investigation of music performance on high-speed networks.
Music 560 Senior Project
Major research or creative project in an area of musical study.
Prerequisite(s): Consent of the Division Chair, Music.
Also known as: (formerly Music History and Literature 596, 598, Music Theory and Composition 596, 598)
Music 561 Independent Study
Individual study in a selected area of music.
Also known as: (formerly Music History and Literature 555, Music Theory and Composition 555, Music Performance 555)
Music 562 Senior Performance Project
Applied instruction in instrument or voice in connection with senior recital.
Prerequisite(s): Admission to the BMus (Performance) program, Music 313 or Music Theory and Composition 303, and Music 333 or Music History and Literature 305.
Various topics (master's level).
Advanced creative and analytic approaches to the study of selected repertoire with an emphasis upon contemporary music.
Music 615 Pedagogy of Music Theory
Refining ideas about music theory and its teaching, while developing and strengthening teaching skills.
Notes: Required course for all PhD (Composition) students.
Music 621 Advanced Performance Practicum I
Music 623 Advanced Performance Practicum II
Prerequisite(s): Music 621 or Music Performance 691.
Various topics such as applied music literature, applied pedagogy, accompanying, phonetics and others.
Music 629 Studies at the Banff Centre
Advanced music studies.
Notes: Although the Banff Centre does not provide credit course instruction, students with advanced experience in music at the Banff Centre may apply for graduate-level credit from the University of Calgary.
MAY BE REPEATED FOR CREDIT NOT INCLUDED IN GPA
Exploring the basic reference materials and techniques for musical research at the graduate level.
Notes: Required course for all MMus and MA (Musicology) students.
Various topics such as history of music theory, analysis, notation, or performance practice may be offered. Consult the timetable for current topic.
Music 637 Pro-Seminar in Music for Graduate Students
Selected works of music from the middle ages to the present in an analytical and historical context.
Music 641 Composition
Music 645 Composition Seminar
Music 651 Selected Topics in Electroacoustic Music
Advanced topics in computer music selected from such subjects as: analysis, theory and aesthetics of electroacoustic repertoire, computer programming and software design, interactivity, performance practice and interpretation, sound morphology, sound spatialization, sound synthesis, soundscape studies, tele-media.
Music 653 Projects in Computer Music
Individual and collaborative creative and research projects in computer music.
Music 711 Advanced Topics in Theory and Composition
Various topics (doctoral level).
Various topics in the field of Musicology (doctoral level).
Individual study in musical composition (doctoral level).
Music 751 Advanced Topics in Electroacoustic Music
Advanced topics in computer music selected from such subjects as: interactivity, tele-media, sound morphology, sound spatialization, analysis, theory and aesthetics, performance practice and interpretation, computer programming and software design, sound synthesis, soundscape studies.
Music 753 Advanced Projects in Computer Music
Individual study in a selected area of music (doctoral level).
2500 University Drive NW, Calgary, AB, Canada T2N 1N4 Switchboard: +1 (403) 220-5110


Two employees working at a Chinese Shop in Francistown are nursing fractured legs after a car drove through the wall on Tuesday morning.
A Toyota 2.7 Double Cab, knocked down a few road signs before smashing into the shop, barely missing customers and hawkers on the sidewalk.
The store manager who refused to state his names told The Voice that two of his employees sustained injuries and would be off-work for sometime.
"I don't want to share the nature of their injuries with the media, but I can confirm they'll be on sick leave for at least a month," he said.
"Talk to the driver, he's a former police officer," said the manager before walking off.
An eye witness Thandiwe Tembo told The Voice that the two employees have sustained leg injuries and were rushed to the hospital immediately.
"One was a cashier and she was at the safe when the car came crashing in. She was thrown off the high stool and it was clear her sheen was broken," she said.
Tembo also said the driver of the vehicle is a well known retired police officer who is not supposed to be driving.
"He has a condition, and is not supposed to be driving," The Voice learnt.
Central Police Station Commander Superintendent Lebalang Maniki confirmed to The Voice that the driver of the vehicle is a former police officer who retired at the rank of Superintendent.
"I'll not comment on allegations of epilepsy, all I can say is we are still investigating to find out what could have caused the car to veer off the road," Maniki said.


. dats not good yaar.
vins, 15 Jan 2014there should be internet connection for it to look on to sd card. turn on internet then it wil... moreI download real racing 2, real football 2013, six guna, dungen hunter 4 and asphalt 8 bt its only identify six guns.cant get the problem with other games.
krishan, 15 Jan 2014Can't identifying the app and games from sd card. Can anybody solve it?there should be internet connection for it to look on to sd card. turn on internet then it will recognize the apps in sd card.
Can't identifying the app and games from sd card. Can anybody solve it?
Owned xperia J fr abot a year..and d battery behaves abnoarmally...when taken to sony gallery they just reload d OS...sony is bad fr indians.my nxt phone is definitely lumia...m sorry nokia fr switchin loyalty.
otherwise buy ugly Samsung . .
or better to buy Samsung phone . . .
AnonD-224187, 14 Jan 2014it hangs like hell,gets warm as a fish grill !! slutters and hangs !! Man understand one thing... moreRight! having high-level hardware can't ensure superior performance. But you should khow that sleeky performance of wp8 can't be replaced with LED flash and Front camera,, Nokia has missed important features in lumia 525.
Good mobile,anytime better than Samsung,earlier i used note one.
shiva, 13 Jan 2014I bought this phone yesterday.All superb features but battery is not that much efficient and i... moreBattery drains very bad, and get hot easy at the back.
I touch my phone most of the time and I required to charge 3 times a day.
No game, only Wifi, facebook, internet, youtube.
Anonymous, 14 Jan 2014There are people who are missing the Flash which is actually logical to ask. But am wonder... moredude if nokia provide flash n frnt cam then it direct affect sells of L62x series.. hope u got main point..
Anonymous, 14 Jan 2014There are people who are missing the Flash which is actually logical to ask. But am wonder... moreHehe..!! speaking of Old Managers..!! They missed the Android train too. It would have been a revolution..!!! Nokia would have rocked...!!!!!!!!!!! Still, they managed to have a decent comeback.
There are people who are missing the Flash which is actually logical to ask.
- Phone is not for camera use, buy a camera if you want flash.
- Some bluntly replying, don't buy the phone.
Understand, flash is basic today and it wont cost Nokia much. It's actually a cheap strategy Nokia employs and it never learns. It's saves on silly things. Like it's basic line of phones available for 2000Rs, you would find Voice leakage problems(saving by removing one speaker) but a local handset for less than 1000 by other brand still works good.
When today, companies are marketing their phones processing power between different models, we have Nokia still worried for Minute differences. I guess, it's the Old Managers who would never want to change.
Also, no where I mentioned Nokia makes bad phones, it's just the Here & There loopholes Nokia intentionally leaves and prove turn off.


Aryl Hydrocarbon Receptor (AhR) is a ligand-activated transcription factor with multiple functions operating in a variety of organs, including the brain. Recent studies have revealed that AhR played a functional role in traumatic injuries. This paper aims to study the expression of AhR during the early phase following a traumatic brain injury (TBI) in rat brains by immunohistochemistry.
Weight-drop induced TBI was performed in rats. The expression of AhR in brain of TBI rats were examined by immunohistochemistry.
Neuron expression of AhR in the rat brains of experiment group had been upregulated since day 3 in lesional hemisphere compared to that of the control group and mainly located in the cytoplasm, indicating an inactivated state. Interestingly, the accumulation of AhR+ non-neuron cells became significant as early as 18 h after injury, which had kept increasing until 24 h post injury and then decreased slowly. For AhR+ non-neuron cells, the AhR mainly located in cell nucleus, indicating a reactive status. Furthermore, double staining showed that most AhR+ non-neuron cells co-localized with W3/13, a marker for T lymphocytes, but not with ED-1 (for activated microglia/macrophages) or GFAP (for activated astrocytes), suggesting that most AhR+ non-neuron cells were T lymphocytes.
This is the first study concerning AhR expression in brains following TBI, and our data demonstrated that AhR was upregulated and activated in T lymphocytes following TBI. More research is needed to make a more conclusive conclusion.
Traumatic brain injury (TBI) is a major public health threat in the society. While the contact and initial force cause multifocal lesions, the secondary injury can be more dreadful and diffuse. Delayed neuronal death in secondary injury can be due to several cellular and subcellular cascades such as release of excitatory amino acid (EAA), influx of Ca++ , and mechanical distortion of the cell membrane .
Immune responses in the CNS have recently drawn lots of attention, despite its long-lasting perception as a site of immune privilege . The infiltration of immune cells following TBI has been well documented for some cell types, including neutrophils, microglia/macrophages and T lymphocytes . Activated neutrophils upregulate adhesion molecules to enhance their association and migration into tissues and produce reactive intermediates, cytokines and chemokines, etc. Activated microglia/macrophages show high heterogeneity, and the activation may be beneficial, deleterious, or neutral . Moreover, functions of T lymphocytes are more complicated. Both CD4+ and CD8+ T cells that enter the brain  and different subsets of T cells are involved in contradictory activities like a double-edged sword . These immune cells orchestrate and lead to neuronal degeneration or regeneration/repair depending on the context . However, details on the changes and exact roles of immune cells following TBI remain scarce.
Aryl Hydrocarbon Receptor (AhR) is a ligand-activated transcription factor of the basic helix-loop-helix/per-ARNT-Sim (bHLH/PAS) superfamily . It can be activated by a variety of exogenous and endogenous compounds . Upon ligand binding, AhR translocates into the nucleus to form an active heterodimeric complex  and triggers rapid transcriptional activations  in a variety of organs and cell systems. In addition to the classical knowledge of responding to environmental toxicants via exogenous ligands, recent studies pointed out that the physiological functions of AhR included cell differentiation, apoptosis [10, 11], immune response,  and injury repairing [13, 14].
AhR was identified in the brain , regulating neuronal cell cycle control and apoptosis . Moreover, AhR has been identified in T lymphocytes and macrophages as a regulator of cytokine production . Recent studies also revealed that AhR is involved in controlling helper T cell differentiation [18, 19]. However, the expression of AhR following TBI remains unknown. Therefore, this experiment was performed to study the spatiotemporal expression of AhR in brains of weight-drop induced TBI rats.
The brain libraries of the control group and the experiment group of rats used in this study have been described previously . In brief, weight-drop induced TBI was performed in Lewis rats. This study was approved by the Ethics Committee of Tuebingen University (No. HF 2/06).
A previous reported protocol for immunohistochemistry was applied to detect the expression of different proteins using following primary antibodies: anti-AhR (1:100; Lifespan Bioscience, Seattle, USA), anti-ED-1 (1:100; Serotec, Oxford, Great Britain) for macrophages, anti-W3/13 (1:100; Serotec, Oxford, Great Britain) for T lymphocytes and anti-glial fibrillary acidic protein for astrocytes (GFAP; 1:500; Chemicon International, Temecula, CA, USA) [20, 21].
After immunostaining, brain sections were examined by light microscopy. For single AhR staining, the numbers of AhR+ cells were counted in 8 non-overlapping high-power fields (HPFs, x400 magnification) for each section. Results were presented as arithmetic means of AhR+ cells per HPF and standard errors of means (SEM). Statistical analysis was performed by one-way ANOVA followed by Dunnett's multiple comparison tests (Graph Pad Prism 4.0 software). The significance levels were set at p < 0.05.
In this study, open skull weight drop injury generates a reproducible local lesion in the ipsilateral cortex. The development of the lesion was first analyzed by Hematoxylin and Eosin (HE) Staining and has been described previously by Zhang . In brief, significant leukocyte infiltration and hemorrhage can be observed at the first day after injury. At day 4 post injury, a lesioned cavity together with its surrounding perilesional tissue loss formed under the impact areas.
The expression of AhR in TBI and non-TBI brains was analyzed by immunohistochemistry. In our applied weight-drop model, cortex is the primary injury site. Moreover, the traumatic impact may influence areas like the hippocampus, resulting in complex cognitive problems. Therefore, the expression of AhR in cortex and hippocampus was mainly investigated. In in the cortex of normal rat brains, weak AhR immunoreactivity (IR) was observed, which mainly localized to neuron cells (Fig. 1a, b). Similarlly, weak IR of AhR was detected in hippocampus of normal rats, which was observed in the pyramid cell layer of CA fields (Fig. 1c, d) and granular layer of dentate gyrus (Fig. 1e).
After TBI, no visible change of AhR IR was detected in the contralateral hemisphere (Data not shown). In the injured (ipsilateral) sides, AhR expression in neuron cells in the cortex outside of lesion and hippocampus was upregulated since day 3. As shown in Fig. 1c, g, h and i, more AhR+ cells were observed and the IR of AhR became stronger as well compared to normal control at day 3 post injury. Interestingly, while an upregulation of AhR was observed following TBI, IR of AhR in neuron cells in the cortex and hippocampus was mainly localized to cytoplasm but not nucleus, indicating an inactivated state.
However, the accumulation of non-neuron AhR+ cells was observed in the lesion areas. We then quantified the non-neuron AhR+ cells in lesional areas. After TBI, a slight increase of AhR+ non-neuron cells was observed to be confined to the lesion as early as 18 h post-injury (p.i.) (Fig. 2; 6.3 ± 1.5 per HPF, p > 0.05 compared to normal control). The maximal accumulation of AhR+ non-neuron cells in the lesional region was observed 24 h p.i. (36.0 ± 7.6 per HPF, P < 0.001; Fig. 2 and Fig. 3b). Thereafter the accumulation of AhR+ non-neuron cells decreased with time but still remained significantly higher than normal control (48 h: 27.2 ± 5.4 per HPF, p < 0.05; 96 h: 15.6 ± 5.4 per HPF, p < 0.05; Fig. 2 and Fig. 3c, d).
At the lesioned site, most of the AhR+ cells exhibited lymphocyte morphology with small cell body and cytoplasm (Fig. 3e). Occasionally, the localization of AhR+ lymphocyte-like cells at the peri-vascular spaces corresponding to peri-vascular spaces was observed, indicating the blood origin (Fig. 3f). More interestingly, in AhR+ non-neuron cells, AhR mainly localized in nucleus, suggesting an activated status (Fig. 3e, f).
To further identify the cellular sources of these non-neuron AhR+ cells in the lesions, we performed double-staining experiments with W3/13 antibody (recognized T lymphocytes), ED-1 antibody (recognized activated microglia/macrophages) and GFAP antibody (recognized astrocytes). As shown in Fig. 4a, b, most non-neuron AhR + cells were co-labeled with W3/13 (more than 90 %). ED-1+ microglia/macrophages and GFAP+ astrocytes very rarely co-expressed AhR near the lesional areas following TBI (Fig. 4c, d). Therefore T cells were the major cellular sources of non neuronal AhR in the lesion areas following TBI.
In this study, the expression of AhR in neurons of normal rat brain was mainly detected in the cortex and hippocampus in a low or moderate level, and occasionally found in the pyramid cell layer of CA fields, which was similar to previous report [15, 22]. In neurons, the expression of AhR increased following TBI but was mainly localized in the cytoplasm, indicating an inactivated state. However, due to the relative insensitivity of our applied method, a small amount of AhR may still exist in nucleus. Under pathological conditions, the over-expression of AhR was reported to induce neural differentiation  and AhR was also involved in controlling neuron cell cycle and apoptosis [11, 19].
The accumulation of AhR+ lymphocytes in lesional areas following TBI was observed in our study. Normally, T cells cannot enter the CNS. However, under pathological conditions, such as activated by CNS-derived auto-antigen and increased blood-brain barrier permeability, T cells can infiltrate into CNS parenchyma and exert multi-functions . Clausen et al. reported that T lymphocytes (both CD4+and CD8+ cells) were detected in the lesional cortex at 12 h after TBI . The reported infiltration, which is similar to our observation, peaked at 24 h and then slightly decreased.
Functions of T cells in brain injury are complicated and conflicting observations have been reported by different groups. Autoreactive Th1 cells by vaccination were reported to improve functional recovery after closed head injury . Moreover, passive transferred autoreactive Th2 cells also accelerate recovery in spinal cord contusion . However, immediate post-lesional transfer of MBP-specific T cells exacerbated lesion pathology in spinal cord contusion . Furthermore, depletion of regulatory T cells (Treg) by CD25 antibody, reported by Liesz et al., profoundly increased delayed brain damage and deteriorated functional outcome in acute experimental stroke . CD8+ T cells were less studied in injury models, but they are proved to infiltrate the lesion after TBI and may also play a part in the pathological process following TBI .
Currently, AhR can be detected in naïve T cells  and its expression was reported in the Th17 and Treg subsets  but not in Th1 or Th2 subsets . Negishi et al. reported a modulation of the naïve Th cell differentiation into Th1/Th2 cells toward Th1 dominance under the activation of AhR treated by representative AhR ligands in vitro . Moreover, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the exogenous AhR ligand, promoted Treg differentiation , while tryptophan photoproducts 6-formylindolo-[3,2-b]-carbazole (FICZ) would promote Th17 cell differentiation [18, 19]. AhR can also be expressed in CD8+ T cells and promote CD8+ Treg cell differentiation under TCDD treatment . In our investigation, accumulation of AhR+ T lymphocytes was observed following TBI. Though the exact function of AhR in TBI still remains unclear, AhR might modulate the differentiation of T lymphocytes to influence the balance of immune response and contribute to the outcome of TBI [28, 29].
Taken together, we have shown an early accumulation of activated AhR+ T cells in TBI. AhR expression might play a role in the degeneration/regeneration processes following TBI by modulating the differentiation of T lymphocytes. Our results warrant future studies of the AhR function in brain trauma.
We thank Prof. Schluesener and Dr. Zhang, Zhi-Yuan from Institute of Brain Research, Tuebingen University, Tuebingen, Germany, for providing the TBI tissue library and kind help with immunostaining.
This research was supported by the National Science and Technology Major Projects of New Drugs (2012ZX09103301035) and the National Natural Science Foundation of China (No. 81471190). Both fundings supported the collection, analysis, and interpretation of data and the writing of the manuscript.
KX participated in study design, execution, analysis and interpretation of data, and drafting the manuscript. RCS participated in study design and execution and analysis of data. ZCY participated in study design, analysis and interpretation of data, and drafting the manuscript. CXL assisted in execution of the study. ZRZ conceived of the study design, participated in data analysis and interpretation, and in drafting the manuscript. All authors read and approved the final manuscript.
The authors declare that this study was approved by the Ethics Committee of Tuebingen University (No. HF 2/06).


This is a great opportunity for pre-season training! Our Canadian coaches from RCYC and RNSYS have been doing this for a few years now and every year the number of participants grows. The venue will be the Coconut Grove Sailing Centre.
Sailors can arrive in Miami March 9th or the morning of March 10th. All boats need to be rigged and ready by noon on March 10th for the beginning of the camp.


text:
Highway 163 (AR 163, Ark. 163, and Hwy. 163) is a north–south state highway in Northeast Arkansas. The highway begins at Wittsburg and runs  northeast to Highway 1, Highway 1 Business (AR 1B) and Crowley's Ridge Parkway (CRP) in Jonesboro. A spur route runs in Jonesboro. All routes are maintained by the Arkansas Department of Transportation (ArDOT). Almost all of the route is concurrent with Crowley's Ridge Parkway, with a portion also serving as an Arkansas Heritage Trail for its use during the Civil War.

Route description
Highway 163 runs in Northeast Arkansas, a region mostly characterized by the Arkansas Delta, a sparsely populated rural area with farms and small settlements. However, Highway 163 runs its entire length along Crowley's Ridge, a small loess ridge rising above the flat Delta. The route passes several cultural and historical points in the region, including a historic cotton gin and an American Civil War trail.

State maintenance begins at Wittsburg near the Wittsburg Store and Gas Station, with the roadway continuing south as a county road. Highway 163 runs north to a junction with US 64 and the Crowley's Ridge Parkway (CRP). The routes briefly overlap to the east, with Highway 163/CRP turning north and passing the John H. Johnston Cotton Gin Historic District and the Capt. Isaac N. Deadrick House, both listed on the National Register of Historic Places. Highway 163/CRP run north, serving as the eastern terminus for Highway 364 and meeting Highway 42 near Birdeye. After crossing into Poinsett County, the routes serve as the southern terminus of Highway 373 before passing Lake Poinsett State Park. Highway 163/CRP intersect Highway 14 east of Harrisburg, including a brief overlap. Continuing north, Highway 163/CRP intersect Highway 214, Highway 158, and Highway 69 before entering Craighead County.

Highway 163 has a junction with Highway 158 in southern Craighead County before turning northwest toward Jonesboro. Shortly after entering the city, Highway 163 Spur begins at the parent route, running north as Apt Drive through a residential subdivision. Highway 163 continues west, intersecting with Highway 1, where it terminates, with the roadway continuing north as Highway 1B.

History
Between Jonesboro and US 64, Highway 163 is designated as an Arkansas Heritage Trail. During the Civil War, Union General John Wynn Davidson used the route to march cavalry from southeast Missouri down Crowley's Ridge, following a rumor Confederate General Sterling Price's army was planning to attack Missouri via Crowley's Ridge. After marching and finding no Confederates, General Davidson headed west and started the Little Rock Campaign in 1863.

The route was established by the Arkansas State Highway Commission (ASHC) on July 10, 1957, beginning at the Poinsett County line and running south through Birdeye to a county road. The southern terminus was extended south by  on September 17, 1958. The route was created in accordance with Act 148 of the 1957 General Assembly. It was extended south to Levesque on June 29, 1960. A second segment was created from Lake Poinsett State Park to Harrisburg on June 23, 1965, though the gap between the routes was closed four months later. The route was extended north to Jonesboro on July 29, 1976; the same order created the spur route.

On June 30, 1983, the route was extended south from Levesque to Wittsburg, along the original 1926 alignment of Highway 163. The extension was made in exchange for decommissioning a segment of Highway 364 at the request of the county judge of Cross County.

Major intersections
Mile markers reset at some concurrencies.

Jonesboro spur

Highway 163 Spur (AR 163S, Ark. 163S, Hwy. 163S, and Apt Drive) is a  spur route in Jonesboro.

Major intersections

Former route

State Road 163 (AR 163, Ark. 163, and Hwy. 163) is a former state highway of  in Cross County, Arkansas. The route began at Wittsburg and ran north to US 64 at Levesque.

History
Highway 163 was created on May 28, 1942. However, the route does not appear on the next statewide map in 1945 nor the Cross County map in 1947.

Major intersections

See also

 List of state highways in Arkansas

Notes

References

Arkansas Heritage Trails System
Crowley's Ridge Parkway
Jonesboro, Arkansas
163
Transportation in Craighead County, Arkansas
Transportation in Poinsett County, Arkansas
Transportation in Cross County, Arkansas

redpajama_set_name: RedPajamaWikipedia


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text:
Opinion|Why Isn't Marco Rubio Winning?
https://nyti.ms/1ZUDvbT
Ross Douthat
Why Isn't Marco Rubio Winning?
By Ross Douthat
Credit...Sam Hodgson for The New York Times
Late in October, when it was still possible to envision a somewhat normal Republican primary season, Marco Rubio and Jeb Bush had a moment on the debate stage that seemed as if it might be a turning point in the campaign.
Bush, the well-funded front-runner whose poll numbers had been sliding since the summer, came prepared to swing at Rubio over his missed votes in the Senate. Rubio, the upstart running against his former mentor, responded with a mix of grace and pity, dismissing Jeb's attack as a desperate flail, taken because "someone has convinced you that attacking me is going to help you."
In the month after that confrontation, Bush's national numbers slipped into the lower single digits, while Rubio's climbed steadily. In early December, he and Ted Cruz both had about 15 percent support in the national polls, below Donald Trump but well above all the other professional politicians in the race. It seemed as if they were rising in tandem, and that Rubio was destined to be the establishment's preferred candidate in a three-man race with Cruz and Trump — and based on past results, the likely nominee.
But instead, Rubio hit a ceiling, while Cruz continued to climb. And despite a long series of "moments" when he was supposed to consolidate his position, the Florida senator is still basically stuck. He's hovering just above 10 percent in national polls and in New Hampshire, trailing Cruz and Trump by a clear margin in Iowa, and still lagging Jeb in the endorsement primary.
Nobody's sure why. Rubio has various weaknesses, but he's well liked by Republican voters, he polls very well against Hillary Clinton, and nothing scandalous has emerged to derail him. Yet here we are just days from Iowa, and prominent Republicans are variously frustrated and confused, resigning themselves to Trump-versus-Cruz or attempting complicated bank shots to take one or both of them out … instead of doing what many people expected and simply rallying to Rubio.
Here are some possible explanations:
It's all about immigration. In a race dominated by Trumpian nationalism, and with immigration restriction increasingly a litmus test for many conservative voters, Rubio's role in the "Gang of Eight" immigration bill is plainly a liability. Possibly enough of a liability, in fact, to deny him the nomination.
At the same time, though, there are still lots of Republican voters who don't consider the immigration issue a top priority, and lots of Republican donors and elected officials for whom Rubio's "Gang of Eight" support is probably an asset. So immigration might explain why he trails Trump and Cruz in Iowa, but not why he can't put away Jeb, Chris Christie and John Kasich.
It's all Jeb's fault. This is the narrative advanced by many of Rubio's supporters, and not only them. In effect, they argue, Jeb's campaign has become an anti-Rubio zombie operation. Even as Bush's own numbers have remained stagnant, his "super PAC," Right to Rise, has spent a fortune on anti-Rubio attack ads. In so doing, The Weekly Standard's Stephen Hayes argues, Team Bush is effectively running a suicide mission against Rubio, whose only "lasting legacy" will be "its prominent role in making Donald Trump the nominee."
This seems a little harsh (and not only because I still don't think Trump will be the nominee). A candidacy that can't survive a run of attack ads isn't a candidacy destined for glory. Rubio has done less than Jeb to take the fight to Trump. And Jeb is about even with his former protégé in New Hampshire polling now, so it's not clear that he's just a zombie at this point.
Still, the Right to Rise onslaught is a decent explanation for Rubio's stagnation. But not a complete one, since it's not as though Jeb actually controls the entire Republican establishment. If his donors were really unhappy with his strategy they could desert en masse to Rubio; if leading Republican politicians felt certain Rubio was the better bet, they could counter Jeb's ads with a wave of endorsements. But they haven't, again despite Rubio's higher favorables and better general election odds. Which raises the possibility that …
Rubio's a little too conservative. Both the Republican donor class and the New Hampshire electorate, in slightly different ways, are more moderate or even liberal than the wider Republican electorate. Meanwhile, as Harry Enten of FiveThirtyEight points out, Rubio is a lot more conservative than his "great establishment hope" image currently suggests.
Moreover, his conservatism is most pronounced on social issues, which makes him culturally alien to both the libertarian and Yankee moderates of New Hampshire and the secular and socially liberal segment of the party's donor base.
Which is why it isn't necessarily surprising that Rubio is polling slightly better in evangelical-heavy Iowa than in New Hampshire, or that he's having trouble putting away more moderate figures like Christie and Kasich in the latter state. It may well be, as Enten suggests, that a lot of Republican bigwigs are just much more politically and culturally comfortable with the other candidates in the establishment "lane," and so they aren't ready to throw in with Rubio's piety and Tea Party-ish voting record until they have no other choice.
Then there also might be a more personal element as well …
Rubio seems a little too ambitious. He's no Ted Cruz, whose naked self-promotion and penchant for making enemies has left him effectively running against the entire institutional party. But as Matt Yglesias of Vox notes, Rubio's ascent has been marked by repeated acts of rebellion and opportunism — many of them successful, all of them quite normal for politicians, but condensed into a relatively narrow span of time.
The G.O.P.'s history as a royalist party is somewhat exaggerated, but it has repeatedly handed nominations to elder statesmen in years when it seems to be their turn, and the royalist tendency is naturally strongest in the party elite. It may not be only Jeb Bush's inner circle that regards Rubio's rise as a little swift, and his decision to run as a little premature, even arrogant. There may be a sense that he needs to prove himself with voters, to actually win a caucus or a primary, before he can lay claim to wide support.
In the quest for that support, he has one glaring problem …
Rubio's strengths might be a bad fit for the 2016 mood. Part of the reason that pundits (myself included) have tended to rate the Florida senator highly as a candidate is that he combines a conservative record with some of the gifts of Bill Clinton circa 1992 and Barack Obama circa 2008 — eloquence, optimism, a strong personal narrative, a clear interest in domestic policy.
But in this election, many Republican voters seem to be looking for a Richard Nixon — a hard man for hard times, you might say, which isn't really a slogan that fits the boyish-looking first term senator.
This is why perhaps — just perhaps — Rubio's strategy of avoiding conflicts with Trump has been a strategic error. A young politician can try to project toughness all he likes, but the only way to actually prove your toughness is to fight the battle that's right in front of you.
And for Rubio, sooner rather than too late, that might mean finding a way to fight with Donald Trump and win.


Next shop update will be on Tuesday with a few tins, tags, and originals.
thanks again for following me here on my blog.
I am still scheduling posts on my instagram but feel my energy around my creativity needs boundaries and have decided to revitalize my blog and will doing more updates here.
Since my instagram break this week, my productivity has increased dramatically and there is a certain calm in my mind around trying to stay informed with comments, likes, and all that crazy stuff. LOL!
So I'm going back to the dark ages of blogging and hope you'll continue to follow me here.
I remember back in 2007 when I first started on etsy, where flickr and blogging where the go to ways of following an artist. And to be honest, I miss those times. I no longer want that feeling of "staying in the know" or those comparison gremlins. I am concentrating on staying focused on my path and art journey.


Look at this beauty! It was most likely made for a leader of a clan, as the size denotes power and authority. I was told the stone was Landers Blue, but I think it may not be. You can see the handmade bezels on all the stones. No mark as would be appropriate with a piece that was made for family. A wonderful piece of jewelry and history.


← Now I ain't cheap, but I can be had.
Posted on March 20, 2019, in Ladies in Defiance and tagged a lady in defiance, adventurous women, feminism, Hearts in Defiance, heather blanton, https://www.pbs.org/weta/thewest/program/episodes/eight/images/6-5.jpg, ladies in defiance, legends of the old west, Old West History, old west legends, unsung heroines of the west, western history, western romance, Westerns, who rode side-saddle, wild west history, Wild West Shows, women and guns, women in american history, women in history, women of the old west, Women of the Wild West, women patriots, women who explored alone, women who overcame, women who settled the west, women who went west, Women who won the west, women's history, women's studies. Bookmark the permalink.	4 Comments.
Wow, what a gal! No victim crap coming from this lady. Amazing, inspirational story Heather. Assuming it's her in the middle of the photo? I'll get the book. Thank you for sharing.
You tickle me, Rita. Yeah, she would have laughed at the feminists of today!
Yep, she was a pistol!


text:
Georgian Films to Be Screened at Sarajevo Film Festival
Georgian Painter Awarded Michelangelo International Prize
Kakhaber Abashidze Appointed as Director General of Walt Disney Company CIS
Biennale Art 2019 & Georgian Artist Anna K.E.
Georgia to Host World-Famous Verdi Festival
NBCUniversal Reps Travel to Georgia, Explore Prospects for Filmmaking
Hollywood Movie to be Shot in Georgia
Artists Recreate Georgian Medival Poem Knight in the Panther's Skin as a Comic Book
Unprecedented warranty offer from HUAWEI
Georgian Opera Singers Feature in Woody Allen Play
Nobel Prize-winning Writer Mario Vargas Llosa Will Visit Georgia
Mario Vargas Llosa, the winner of the 2010 Nobel Prize in Literature, will visit Georgia in September to learn about Georgian culture and arts.
The Georgian Ministry of Education, Science, Culture, and Sport announced that the internationally acclaimed author's visit at a press conference on Thursday. The Ministry and the Georgian National Book Centre will host Vargas Llosa during his 5-day stay.
Vargas Llosa, one of the most significant Latin American writers, has been a prominent literary figure since the 1960s. He wrote novels such as 'The Time of the Hero', 'The Green House', and 'Conversation in the Cathedral. His works focus on Peruvian society, as well as global issues like nationalism. He has also written for newspapers such as El Pais.
Vargas Llosa was awarded the 2010 Nobel Prize for his "cartography of structures of power and his trenchant images of the individual's resistance, revolt, and defeat."
His stay in Georgia will be his first trip to the South Caucasus.
By Amy Jones
Photo source: El Pais


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