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Will Muschamp was 'helping out a little bit' during Outback Bowl
Turns out Will Muschamp was a bit more than a passive observer during the Outback Bowl
Will Muschamp was 'helping out a little bit' during Outback Bowl Turns out Will Muschamp was a bit more than a passive observer during the Outback Bowl Check out this story on montgomeryadvertiser.com: https://on.mgmadv.com/1apeKCv
James Crepea, Montgomery Advertiser Published 10:31 p.m. CT April 2, 2015 | Updated 10:32 p.m. CT April 2, 2015
Newly-hired Auburn defensive coordinator Will Muschamp shakes hands with defensive lineman Angelo Blackson before the Outback Bowl on Thursday. Muschamp was the former head coach at Florida. (Photo: CHRIS O'MEARA/AP)
AUBURN -- Turns out Will Muschamp was a bit more than an observer during the Outback Bowl.
Auburn coach Gus Malzahn insisted Muschamp was only "listening" and "observing" while seated in the press box with a headset on as interim defensive coordinator Charlie Harbison supposedly ran the defense during Auburn's 34-31 overtime loss to Wisconsin on New Year's Day. But Muschamp did much more than that, including an impassioned halftime speech reminiscent of one he gave while at Texas.
"Me and LaDarius Owens were watching a video ... and he had said something, and he punched the board," defensive tackle Montravius Adams said. "And then at halftime, I swear it was like a replay in my head, same thing at Wisconsin."
NCAA rules only permit teams to have nine full-time assistant coaches and Auburn promoted defensive analyst Travis Williams to linebackers coach for the Outback Bowl after Ellis Johnson was fired.
Asked whether he coached in the game, Muschamp said he was "helping out a little bit. Obviously it didn't work. It wasn't very good."
Auburn's defense also made a series of personnel changes in the game, with Josh Holsey seeing no time after practicing earlier in the week and Derrick Moncrief playing at the "star" position. The Tigers also used a three-man front, which had never been utilized by Johnson.
All the moves did nothing to slow Wisconsin, which gained 521 yards, including 251 and three touchdowns by Melvin Gordon, the most rushing yards ever allowed by Auburn.
Harbison and cornerbacks coach Melvin Smith were fired immediately after the game. They are both now at Louisiana-Lafayette, with Smith serving as defensive coordinator.
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Washington: NASA Administrator Jim Bridenstine has a vision for renewed and "sustainable" human exploration of the moon, and he cites the existence of water on the lunar surface as a key to chances for success.
The discovery holds tantalizing implications for efforts to return humans to the moon for the first time in half a century. The presence of water offers a potentially valuable resource not only for drinking but for producing more rocket fuel and oxygen to breathe.
Bridenstine, a former U.S. Navy fighter pilot and Oklahoma congressman tapped by President Donald Trump in April as NASA chief, spoke about "hundreds of billions of tons" of water ice that he said were now known to be available on the lunar surface.
Although the moon was long believed to be entirely dry or nearly devoid of moisture, scientists have found increasing evidence in recent years that water exists there.
A NASA rocket sent crashing into a permanently shadowed lunar crater near the moon's south pole in 2009 kicked up a plume of material from beneath the surface that included water.
A study published the following year in the Proceedings of the National Academy of Sciences concluded that water is likely widespread within the moon's rocky interior, in concentrations ranging from 64 parts per billion to five parts per million.
Bridenstine spoke to Reuters about making the next generation of lunar exploration a "sustainable enterprise," using rockets and other space vehicles that could be used again and again.
"So we want tugs that go from Earth orbit to lunar orbit to be reusable. We want a space station around the moon to be there for a very long period of time, and we want landers that go back and forth between the space station around the moon and the surface of the moon," Bridenstine said.
NASA's previous program of human moon exploration ended with the Apollo 17 mission in 1972.
The Trump administration's $19.9 billion budget proposal for NASA for the fiscal year beginning Oct. 1 includes $10.5 billion for human space exploration.
The budget supports development of NASA's new Space Launch System rocket and the Orion spacecraft designed to carry a crew into space. The administration envisioned a SLS/Orion test flight around the moon without a crew in 2020, followed by a fly-around mission with a crew in 2023.
As part of the budget proposal, NASA also is planning to build the Lunar Orbital Platform-Gateway – a space station in moon orbit – in the 2020s. NASA said the power and propulsion unit, its initial component, is targeted to launch in 2022.


The professional home remedy services business is an increasing concern. Hence, in the event that you're competent with both major and minor home repairs, you are comfortable using tools and are able to work well with the others, then establishing your own business is something to be considered. While smaller companies do take the time to become recognized and failure rates are high, there's the chance of becoming a business owner.
A franchise owner of handyman home repair services cool gadgets has assembled in benefits, like an established name in addition to a fantastic customer base. Starting a business on your own means spending a lot of money on advertising, time and energy to set up your company within your community, plus it may take years until you become financially stable. However with a qualified handyman franchise, then you're ahead of the game in terms of individuals knowing the name and additionally having a customer base to utilize.
House repair services might be done by one person who works while the owner and only employee of the company. But him or her can struggle when problems arise. By being a portion of a professional franchise, some of those issues may be eliminated or diminished out of service from the business. You may require advice or specific tools and materials and also the firm can often provide information and suggestions on what to do to get your company a success. It needs to be noted howeverthat buying into a company isn't affordable.
Handyman repair services may be a very competitive industry, and also for a small business owner it may be difficult to grow as fast as desirable. Being part of a company offering House improvement services means that you have access to lots of advice and resources which may help keep you upwardly-mobile. You ought to observe a massive boost in your earnings and more opportunities to take your business plans into the next level.
For some, linking a franchise of professional home repair services provides a number of benefits to cancel the first investment of starting up. For many others, it's preferable to stay small and retain more control over exactly what you can and cannot do. Figure out what your goals are and how you can best reach them. Being the owner of your very own independent business has its own advantages, but now being a company also has its advantages. Decide which path is best for you personally.


First things first: I should define what exactly I mean by "hard." There are scads of ways something can be difficult, and comparing them doesn't always make sense. Compare, for example, a Rubik's cube and running a mile in under five minutes. It's tough to say which is harder, because a.) they're both ridiculously hard in the first place and b.) they're completely different skills, so it depends on who you are and what you're good at.
SAT math is so straightforward a test that only one skill is tested. There are a few different aspects, so the hardest questions can be hard in different ways.
If you don't already know what's on the SAT, this part might come as a relief. The test doesn't go deep into high-level math. There's no trigonometry, no precalculus, no statistics—nothing that you get in advanced math classes during your last year or two of high school. The most advanced math on the SAT are functions and parabolas, but even then you'll see just a couple related questions on your test and you only need to know the bare minimum about how they work.
That said, you really have to know your rules when it comes to algebra, geometry, and number properties. There's nothing particularly advanced, but there is a lot of detail. If you're not confident with the first few sets of Pythagorean triples or aren't sure what a negative exponent means, then you have some brushing up to do. The toughest questions do rely on those details, but that's not what makes them really tough.
Even if you do know the exponent rules well, how quickly and confidently can you apply them to a question like this one?
If k, n, x, and y are positive numbers satisfying x^(-4/3) = k^(-2) and y^(4/3) = n^2, what is (xy)^(-2/3) in terms of n and k?
It's easy to slip up if you're working with rules that you don't use often, and that's precisely what this question relies on to make it difficult. (This is a real SAT question from a past test, by the way.) All of the math that goes into it is relatively straightforward, but if you're not used to answering questions that work with tricky exponents, then you're in danger of faceplanting.
This is what makes the SAT special, and it's why people find themselves actually enjoying SAT questions more than they might expect. The math is part puzzle, really. When a question is really tough, you have to do more than just know the rules and apply them. You also have to figure out the fastest way to arrive at an answer and see unexpected questions between the information.
The hardest SAT math is not based entirely on what you've learned or memorized; it wants you to explore and find patterns for yourself. Check out some examples to see what I mean—can you find shortcuts, when they're possible? Can you remember all the rules you need to and apply them when working under pressure?
Lucas Verney-Fink is a resident TOEFL and SAT expert at Magoosh. Standardized tests and English grammar are two of Lucas's favorite things, and he's been teaching both since 2008. Between his time at Bard College and his time spent teaching abroad, he's tried to learn a total of three other languages. He speaks none of them well.
You can follow Lucas on Google+.


Uncanny X-Men is back and on a weekly basis. Everyone's favorite Marvel mutants are back in the proper place. Marvel's previous ResurreXion initiative was just a warm-up, now we're in for a real return to greatness.
Our new weekly series is wasting no time in establishing itself as a 90's X-Men comic with more to say. Writers Ed Brisson, Kelly Thompson and Matthew Rosenberg are quickly finding a groove together, not stepping on each other's toes or making the script seem disjointed.
There's a major Madrox problem and our teams are split-up handling crisis' of all sorts. There's a lot happening but the pace and screen time for each character makes this an easily digestible epic that fans of any amount of familiarity (or lack of) can jump in.
Rosenberg's recent Multiple Man mini-series gave us a brilliant, fresh take on Jamie Madrox. Utilizing him here as an unpredictable mystery problem is exciting. Remember the recent years when there were ZERO appearances by Jamie in an X-Men title?
One of the major adjustments and strengths this series has early on is the roster chemistry. All of these interactions are satisfying, no matter how seemingly minor. Our trio of writers have been doing their homework (probably for a very long time) and have no issue settling into the voices of their characters.
Juggling multiple subplots does a lot of good for Uncanny X-Men in an effort to make this series feel like the X-Men stories of old. Thompson, Brisson, and Rosenberg are tapping into the elements that worked for ResurreXion and discarding the safety net. We're going to get some stories that push boundaries in a time where we could really use it.
Having one of those subplots focus on the younger mutants, yet to become full-time X-Men, is crucial. Every successful era of X-Men has a young crop of students looking to make the big league roster. This group has been cooking for years now and it looks like they'll finally be taking steps towards finally graduating.
Uncanny X-Men #2 ends with the arrival of David Haller (Legion), another classic character added to an already stacked cast. It'll be interesting to see what this creative team does with Legion, he's a character that works best the deeper you dive into the weird.
Most of the nostalgic appeal comes from the art team. R.B. Silva's pencils are smooth and precise. The redesigns we've gotten so far are sleek and practical for comic book crafting purposes. There are a lot of new, distinct designs but none of them are drastic or desperate attempts to leave a "mark" on the character.
Rachelle Rosenberg is one of the best colorists in the business, it was a wise choice to hire her to add a ton of life and layer to Uncanny X-Men. She's got a tough job in managing this massive cast of colorful characters without any of them looking too similar and she's doing great work.
Inker Adriano Di Benedetto and letterer Joe Caramagna play their part in making sure Uncanny X-Men is the complete package. The inks don't take anything away from Silva's pencils, only strengthen them. This art team is strong, the real test comes with how we fair trying to keep up with the weekly release schedule.
Uncanny X-Men #2 keeps the pace and energy level of the massive introductory issue. This is truly the ResurreXion we were promised by Marvel a year ago. That first batch of Gold and Blue books was an appetizer, now we're back in serious business!
The series has gotten off to a great start and we haven't even touched anything with Adamantium or eye-beams.


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Financial War: Russia & China vs U.S. & NATO
September 13, 2022 September 13, 2022 ~ Eric
The financial war between Russia with China's tacit backing on one side, and America and her NATO allies on the other has escalated rapidly. It appears that President Putin was thinking several steps ahead when he launched Russia's attack on Ukraine.
We have seen sanctions fail. We have seen Russia achieve record export surpluses. We have seen the rouble become the strongest currency on the foreign exchanges.
We are seeing the west enter a new round of European monetary inflation to pay everyone's energy bills. The euro, yen, and sterling are already collapsing — the dollar will be next. From Putin's point of view, so far, so good.
Russia has progressed her power over Asian nations, including populous India and Iran. She has persuaded Middle Eastern oil and gas producers that their future lies with Asian markets, and not Europe. She is subsidising Asia's industrial revolution with discounted energy. Thanks to the west's sanctions, Russia is on its way to confirming Halford Mackinder's predictions made over a century ago, that Russia is the true geopolitical centre of the world.
There is one piece in Putin's jigsaw yet to be put in place: a new currency system to protect Russia and her allies from an approaching western monetary crisis. This article argues that under cover of the west's geopolitical ineptitude, Putin is now assembling a new gold-backed multi-currency system by combining plans for a new Asian trade currency with his new Moscow World Standard for gold.
Currency developments under the radar
Unreported by western media, there are some interesting developments taking place in Asia over the future of currencies. Earlier this summer, it emerged that Sergei Glazyev, a senior Russian economist and Minister in charge of the Eurasian Economic Commission (EAEU), was leading a committee planning a new trade currency for the Eurasian Economic Union.
As put forward in Russian and EAEU media, the new currency is to be comprised of a mixture of national currencies and commodities. A weighting of some sort was suggested to reflect the relative importance of the currencies and commodities traded between them. At the same time, the new trade settlement currency was to be available to any other nation in the Shanghai Cooperation Organisation and the expanding BRICS membership. The ambition is for it to become an Asia-wide replacement for the dollar.
More specifically, the purpose is to do away with the dollar for trade settlements on cross-border transactions between participants. It is worth noting that any dollar transaction is reflected in US banks through the correspondent banking system, potentially giving the US authorities undesirable economic intelligence, and information on sanction-busting and other activities deemed illegal or undesirable by the US authorities. Furthermore, any transaction involving US dollars becomes a matter for the US legal system, giving US politicians the authority to intervene wherever the dollar is used.
As well as removing these disadvantages, through the inclusion of a basket of commodities there appears to be an acceptance that the new trade currency must be more stable in terms of its commodity purchasing power than exists with that of the dollar. But we can immediately detect flaws in the outline proposal. The mooted inclusion of national currencies in the basket is not only an unnecessary complication, but any nation joining it would presumably trigger a wholesale rebalancing of the currency's composition.
Including national currencies is a preposterous suggestion, as is any suggestion that the commodity element should be weighted by trade volumes transacted between participating states. Instead, an unweighted average of energy, precious metals, and base metals makes more sense, but even that does not go far enough. The reasons are illustrated by the two charts in Figure 1.
The upper chart shows baskets of different categories of commodities indexed and priced in dollars. Between them, they represent a wide range of commodities and raw materials. These baskets are considerably less volatile than their individual components. For example, since April 2020 oil has risen from a distorted minus figure to a high of $130, whereas the energy basket has risen only 6.3 times, because other components have not risen nearly as much as crude oil and some components might be rising while others might be falling. Agriculture raw materials are comprised of cotton, timber, wool, rubber, and hides, not raw materials liable to undesirable seasonality. But the average of the four categories is considerably more stable than its components (the black line).
We are moving towards price stability. However, all commodities are priced in US dollars, which being undesirable, cannot be avoided. Pricing in gold, which is legal money, eventually resolves this problem because it can be fixed against participating currencies. The result of pricing the commodity categories in gold and the average of them is shown in the lower chart.
Since 1992, the average (the black line) has varied between 0.37 and 1.66, and is currently at 0.82, or 18% less than in January 1992. This is as stable as it gets, and even this low volatility would probably be less if the dollar wasn't itself so volatile and the gold price manipulated by nay-saying western authorities. To further illustrate these points, Figure 2 shows the dollar's volatility in terms of crude oil.
Before the abandonment of Bretton Woods in 1971, the price of oil hardly changed. Since then, measured by gold the dollar has lost 98% of its purchasing power. Furthermore, the chart shows that it is the dollar which is extremely volatile and not oil, because the price of oil in gold is relatively constant (down only 20% from 1950), while in dollars it is up 33.6 times with some wild price swings along the way. Critics of measuring prices in gold ignore the fact that legal money is gold and not paper currencies or bank credit: attempts by governments and their epigones to persuade us otherwise are propaganda only.
Therefore, Glazyev should drop currencies from the proposed basket entirely and strive to either price a basket of non-seasonal commodities in gold, or alternatively simply reference the new currency to gold in a daily fix. And as the charts above confirm, there is little point in using a basket of commodities priced in dollars or gold when it is far simpler for the EAEU nations and for anyone else wishing to participate in the new trade currency to use a trade currency directly tied to the gold price. It would amount to a new Asian version of a Bretton Woods arrangement and would need no further adjustment.
Attributing them to excessive credit, from recent statements by President Putin it is clear he has a better understanding of currencies and the west's inflationary problems than western economists. Intellectually, he has long demonstrated an appreciation of the relationship between money, that is only gold, and currency and credit. His knowledge was further demonstrated by his insistence that the "unfriendlies" pay for energy in roubles, taking control of the media of energy exchange into Russia's own hands and away from those of his enemies.
In short, Putin appears to understand that gold is money and that the rest is unreliable, weaponizable, credit. So, why does he not just command a new trade currency to be created, backed by gold?
Enter the new Moscow gold standard
Logic suggests that a gold-backed currency will be the outcome of Glazyev's EAEU committee's trade currency deliberations after all, because of a subsequent announcement from Moscow concerning a new Russian bullion market.
In accordance with western sanctions, the London Bullion Market refused to accept Russian mined and processed gold. It was then natural for Russia to propose a new gold market based in Moscow with its own standards. It is equally sensible for Moscow to set up a price fixing committee, replicating that of the LBMA. But instead of it being the basis for a far larger unallocated gold deposit account offering by Russian and other banks, it will be a predominantly physical market.
Based in Moscow, with a new market called the Moscow International Precious Metals Exchange, the Moscow Gold Standard will incorporate some of the LBMA's features, such as good delivery lists with daily, or twice daily fixings. The new exchange is therefore being promoted as a logical replacement for the LBMA.
But could that be a cover, with the real objective being to provide a gold link to the new trade currency planned by Glazyev's EAEU committee? Timing suggests that this may indeed be the case, but we will only know for sure as events unfold.
If it is to be backed by gold, the considerations behind setting up a new trade currency are fairly straightforward. There is the Chinese one kilo bar four-nines standard, which is widely owned, has already been adopted throughout Asia, and is traded even on Comex. Given that China is Russia's long-term partner, that is likely to be the standard unit. The adoption of the Chinese standard in the new Moscow exchange is logical, simplifying the relationship with the Shanghai Gold Exchange, and streamlining fungibility between contracts, arbitrage, and delivery.
Geopolitics suggest that the simple proposition behind the establishment of a new Moscow exchange will fit in with a larger trans-Asia plan and is unlikely to move at the glacial pace of developments between Russia and China to which we have become accustomed. The gold question has become bound up in more rapid developments triggered by Russia's belligerence over Ukraine, and the sanctions which quickly followed.
There can be little doubt that this must be leading to a seismic shift in gold policy for the Russian Chinese partnership. The Chinese in particular have demonstrated an unhurried patience that befits a nation with a sense of its long history and destiny. Putin is more of a one-man act. Approaching seventy years old, he cannot afford to be so patient and is showing a determination to secure a legacy in his lifetime as a great Russian leader. While China has made the initial running with respect to gold policy, Putin is now pushing the agenda more forcefully.
Before Russia's invasion of Ukraine, the strategy was to let the west make all the geopolitical and financial mistakes. For Putin perhaps, the lesson of history was informed by Napoleon's march to the gates of Moscow, his pyrrhic victory at Borodino, and his defeat by the Russian winter. Hitler made the same mistake with Operation Barbarossa. From Putin's viewpoint, the lesson was clear — Russia's enemies defeat themselves. It was repeated in Afghanistan, where the American-led NATO enemy was conquered by its own hubris without Putin having to lift so much as a finger. That is why Russia is Mackinder's Pivot Area of the World Island. It cannot be attacked by navies, and supply line requirements for armies make Russia's defeat well-nigh impossible
Following the Ukraine invasion, Putin's financial strategy has become more aggressive, and is potentially at odds with China's economic policy. Being cut off from western markets, Putin is now proactive, while China which exports goods to them probably remains more cautious. But China knows that western capitalism bears the seeds of its own destruction, which would mean the end of the dollar and the other major fiat currencies. An economic policy based on exports to capitalistic nations would be a passing phase.
China's gold policy was aways an insurance policy against a dollar collapse, realising that she must not be blamed for the west's financial destruction by announcing a gold standard for the yen in advance of it. It would be a nuclear equivalent in a financial war, only an action to be taken as a last resort.
Developments in Russia have changed that. It is clear to the Russians, and most likely the Chinese, that credit inflation is now pushing the dollar into a currency crisis in the next year or two. Preparations to protect the rouble and the yuan from the final collapse of the dollar, long taught in Marxist universities as inevitable, must assume a new urgency. It would be logical to start with a new trade settlement currency as a testbed for national currencies in Asia, and for it to be set up in such a way that it would permit member states to adopt gold standards for their own currencies as well.
Possession of bullion is key
The move away from western fiat currencies to gold backed Asian currencies requires significant gold bullion ownership at the least. The only members, associates, and dialog partners of the Shanghai Cooperation Organisation and the EAEU whose central banks have not increased their gold reserves since the Lehman failure when the credit expansion of dollars began in earnest, are minor states. Since then, between them they have added 4,645 tonnes to their reserves, while all the other central banks account for only 781 tonnes of additional gold reserves.
But central bank reserves are only part of the story, with nations running other, often secret national bullion accounts not included in reserves. The appendix to this article shows why and how China almost certainly accumulated an undeclared quantity of bullion, likely to be in the region of 25,000 tonnes by 2002 and probably more since.
Since 2002, when the Shanghai Gold Exchange opened and China's citizens were permitted for the first time to own gold, gold delivered into public hands has totalled a further amount of over 20,000 tonnes. While the bulk of this is jewellery and some has been returned to the SGE as scrap for re-refining, it is clear that the authorities have encouraged Chinese citizens to retain gold for themselves, which traditionally has been real money in China.
According to Simon Hunt of Simon Hunt Strategic Services, as well as declared reserves of 2,301 tonnes Russia also holds gold bullion in its Gosfund (the State Fund of Russia) bringing its holdings up to 12,000 tonnes. This is significantly greater than the 8,133 tonnes declared by the US Treasury, over which there are widespread doubts concerning the veracity of its true quantity.
Obviously, the Asian partnership has a very different view of gold from the American hegemon. Furthermore, in recent months evidence has confirmed what gold bugs have claimed all along, that the Bank for International Settlements and major bullion operators such as JPMorgan Chase have indulged in a price suppression scheme to discourage gold ownership and to divert bullion demand into synthetic unallocated accounts.
The secrecy that surrounds reporting of gold reserves to the IMF raises further suspicions over the true position. Furthermore, there are leases and swaps between central banks, the BIS, and bullion dealers that lead to double counting and bullion recorded as being in possession of governments and their central banks but being held by other parties.
As long ago as 2002 when the gold price was about $300 per ounce, Frank Veneroso, who as a noted analyst spent considerable time and effort identifying central bank swaps and leases, concluded that anything between 10,000 and 15,000 tonnes of government and central bank gold reserves were out on lease or swapped — that is up to almost half the total official global gold reserves at that time. His entire speech is available on the Gold Antitrust Action Committee website, but this is the introduction to his reasoning:[i]
"Let's begin with an explanation of gold banking and gold derivatives.
"It is a simple, simple idea. Central banks have bars of gold in a vault. It's their own vault, it's the Bank of England's vault, it's the New York Fed's vault. It costs them money for insurance – it costs them money for storage— and gold doesn't pay any interest. They earn interest on their bills of sovereigns, like US Treasury Bills. They would like to have a return as well on their barren gold, so they take the bars out of the vault and they lend them to a bullion bank. Now the bullion bank owes the central bank gold—physical gold—and pays interest on this loan of perhaps 1%. What do these bullion bankers do with this gold? Does it sit in their vault and cost them storage and insurance? No, they are not going to pay 1% for a gold loan from a central bank and then have a negative spread of 2% because of additional insurance and storage costs on their physical gold. They are intermediaries—they are in the business of making money on financial intermediation. So they take the physical gold and they sell it spot and get cash for it. They put that cash on deposit or purchase a Treasury Bill. Now they have a financial asset—not a real asset—on the asset side of their balance sheet that pays them interest—6% against that 1% interest cost on the gold loan to the central bank. What happened to that physical gold? Well, that physical gold was Central Bank bars, and it went to a refinery and that refinery refined it, upgraded it, and poured it into different kinds of bars like kilo bars that go to jewellery factories who then make jewellery out of it. That jewellery gets sold to individuals. That's where those physical bars have wound up—adorning the women of the world…
"We have gotten, albeit crude, estimates of gold borrowings from the official sector from probably more than 1/3 of all the bullion banks. We went to bullion dealers, and we asked, "Are these guys major bullion bankers, medium bullion bankers, or small-scale bullion bankers?" We classified them accordingly and from that we have extrapolated a total amount of gold lending from our sample. That exercise has pointed to exactly the same conclusion as all of our other evidence and inference—i.e., something like 10,000 to 15,000 tonnes of borrowed gold."
Veneroso's findings were stunning. But two decades later, we have no idea of the current position. The market has changed substantially since 2002, and today it is thought that swaps and leases are often by book entry, rather than physical delivery of bullion into markets. But the implications are clear: if Russia or China cared to declare their true position and made a move towards backing their currencies with gold or linking them to gold credibly, it would be catastrophic for the dollar and western fiat currencies generally. It would amount to a massive bear squeeze on the west's longstanding gold versus fiat policy. And remember, gold is money, and the rest is credit, as John Pierpont Morgan said in 1912 in evidence to Congress. He was not stating his opinion, but a legal fact.
In a financial crisis, the accumulated manipulation of bullion markets since the 1970s is at significant risk of becoming unwound. The imbalance in bullion holdings between the Russian Chinese camp and the west would generate the equivalent of a financial nuclear event. This is why it is so important to understand that instead of being a longstop insurance policy against the Marxist prediction of capitalism's ultimate failure, it appears that the combination of planning for a new trade currency for Asian nations centred on members of the EAEU, coinciding with the introduction of a new Moscow-based bullion standard, is now pre-empting financial developments in the west. That being the case, a financial nuclear bomb is close to being triggered.
China's gold policy
China actually took its first deliberate step towards eventual domination of the gold market as long ago as June 1983, when regulations on the control of gold and silver were passed by the State Council. The following Articles extracted from the English translation set out the objectives very clearly:
Article 1. These Regulations are formulated to strengthen control over gold and silver, to guarantee the State's gold and silver requirements for its economic development and to outlaw gold and silver smuggling and speculation and profiteering activities.
Article 3. The State shall pursue a policy of unified control, monopoly purchase and distribution of gold and silver. The total income and expenditure of gold and silver of State organs, the armed forces, organizations, schools, State enterprises, institutions, and collective urban and rural economic organizations (hereinafter referred to as domestic units) shall be incorporated into the State plan for the receipt and expenditure of gold and silver.
Article 4. The People's Bank of China shall be the State organ responsible for the control of gold and silver in the People's Republic of China.
Article 5. All gold and silver held by domestic units, with the exception of raw materials, equipment, household utensils and mementos which the People's Bank of China has permitted to be kept, must be sold to the People's Bank of China. No gold and silver may be personally disposed of or kept without authorization.
Article 6. All gold and silver legally gained by individuals shall come under the protection of the State.
Article 8. All gold and silver purchases shall be transacted through the People's Bank of China. No unit or individual shall purchase gold and silver unless authorised or entrusted to do so by the People's Bank of China.
Article 12. All gold and silver sold by individuals must be sold to the People's Bank of China.
Article 25. No restriction shall be imposed on the amount of gold and silver brought into the People's Republic of China, but declaration and registration must be made to the Customs authorities of the People's Republic of China upon entry.
Article 26. Inspection and clearance by the People's Republic of China Customs of gold and silver taken or retaken abroad shall be made in accordance with the amount shown on the certificate issued by the People's Bank of China or the original declaration and registration form made on entry. All gold and silver without a covering certificate or in excess of the amount declared and registered upon entry shall not be allowed to be taken out of the country.
These articles make it clear that only the People's Bank was authorised to acquire or sell gold on behalf of the state, without limitation, and that citizens owning or buying gold were not permitted to do so and must sell any gold in their possession to the People's Bank.
Additionally, China has deliberately developed her gold mine production regardless of cost, becoming the largest producer by far in the world.[ii] State-owned refineries process this gold along with doré imported from elsewhere. Virtually none of this gold leaves China, so that the gold owned today between the state and individuals continues to accumulate.
The regulations quoted above formalised the State's monopoly over all gold and silver which is exercised through the Peoples Bank, and they allow the free importation of gold and silver but keep exports under very tight control. The intent behind the regulations is not to establish or permit the free trade of gold and silver, but to control these commodities in the interest of the state.
This being the case, the growth of Chinese gold imports recorded as deliveries to the public since 2002, when the Shanghai Gold Exchange was established and the public then permitted to buy gold, is only the more recent evidence of a deliberate act of policy embarked upon thirty-nine years ago. China had been accumulating gold for nineteen years before she allowed her own nationals to buy when private ownership was finally permitted. Furthermore, the bullion was freely available, because in seventeen of those years, gold was in a severe bear market fuelled by a combination of supply from central bank disposals, leasing, and increasing mine production, all of which I estimate totalled about 59,000 tonnes. The two largest buyers for all this gold for much of the time were private buyers in the Middle East and China's government, with additional demand identified from India and Turkey. The breakdown from these sources and the likely demand are identified in the table below:
In another context, the cost of China's 25,000 tonnes of gold equates to roughly 10% of her exports over the period, and the eighties and early nineties in particular also saw huge capital inflows when multinational corporations were building factories in China. However, the figure for China's gold accumulation is at best informed speculation. But given the determination of the state to acquire gold expressed in the 1983 regulations and by its subsequent actions, it is clear China had deliberately accumulated a significant undeclared stockpile by 2002.
So far, China's long-term plans for the acquisition of gold appear to have achieved some important objectives. To date, additional deliveries to the public through the SGE now total over 20,000 tonnes.
China's motives
China's motives for taking control of the gold bullion market have almost certainly evolved. The regulations of 1983 make sense as part of a forward-looking plan to ensure that some of the benefits of industrialisation would be accumulated as a risk-free national asset. This reasoning is similar to that of the Arab nations capitalising on the oil-price bonanza only ten years earlier, which led them to accumulate their hoard, mainly held in private as opposed to government hands, for the benefit of future generations. However, as time passed the world has changed substantially both economically and politically.
2002 was a significant year for China, when geopolitical considerations entered the picture. Not only did the People's Bank establish the Shanghai Gold Exchange to facilitate deliveries to private investors, but this was the year the Shanghai Cooperation Organisation formally adopted its charter. This merger of security and economic interests with Russia has bound Russia and China together with a number of resource-rich Asian states into an economic bloc. When India, Iran, Mongolia, Afghanistan, and Pakistan join (as they now have or are already committed to do), the SCO will cover more than half the world's population. And inevitably the SCO's members are looking for an alternative trade settlement system to using the US dollar.
At some stage China with her SCO partner, Russia, might force the price of gold higher as part of their currency strategy. You can argue this from an economic point of view on the basis that possession of properly priced gold will give her a financial dominance over global trade at a time when we are trashing our fiat currencies, or more simply that there's no point in owning an asset and suppressing its value for ever. From 2002 there evolved a geopolitical argument: both China and Russia having initially wanted to embrace American and Western European capitalism no longer sought to do so, seeing us as soft enemies instead. The Chinese public were then encouraged, even by public service advertising, to buy gold, helping to denude the west of her remaining bullion stocks and to provide market liquidity in China.
What is truly amazing is that the western economic and political establishment have dismissed the importance of gold and ignored all the warning signals. They do not seem to realise the power they have given China and Russia to create financial chaos as a consequence of gold price suppression. If they do so, which seems to be only a matter of time, then London's fractional reserve system of unallocated gold accounts would simply collapse, leaving Shanghai as the only major physical market.
This is probably the final link in China's long-standing gold strategy, and through it a planned domination of the global economy in partnership with Russia and the other SCO nations. But as noted above, recent events have brought this outcome forward.
[i] See https://www.gata.org/node/4249
[ii] Following covid, China's production has declined from over 400 tonnes annually to closer to 300 tonnes.
Source: GSI Exchange
Posted in Asymmetrical Warfare, Chaos Variants, Current Events, Tech Ecosphere Agricultural Raw MaterialsAsiaBank of International SettlementsBelt and RoadBretton WoodsBRICSBullionChinaCommoditiesdollarEnergyEurasian Economic CommissionEuroFractional Reserve BankingGasGlobal TradeGoldIndiaIranJP MorganLondonMarkersMoscowmultipolarityNATOOilPutinRubleRussiaShanghaiShanghai Cooperation OrganizationUkraineUnited StatesXi Jinping
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Only Hungary's Viktor Orbán hasn't backed the German MEP.
Manfred Weber secured the support of seven of the eight heads of EU countries belonging to the European People's Party for his bid to be European Commission president, EPP officials said.
Two EPP officials said "official letters of support" for Weber had been received from the prime ministers of Bulgaria, Croatia, Cyprus and Ireland, as well as the Austrian chancellor and the National Liberal Party of the Romanian president.
Weber already had the support of his fellow German, Chancellor Angela Merkel. That means the only conservative leader who hasn't declared his support for Weber is Viktor Orbán, the Hungarian prime minister.
The letter from Irish Prime Minister Leo Varadkar, addressed to EPP president Joseph Daul and seen by POLITICO, says he will "formally endorse" Weber because the Bavarian MEP is "a politician and a person with the experience, vision and determination to be an excellent president of the European Commission."
"I believe he is, and will continue to be, a unifying personality in European politics," Varadkar added.
Weber, 46, who is the leader of the EPP in the European Parliament, declared last month that he wants to be the party's Spitzenkandidat, or lead candidate, for European Commission president.
If he secures the nomination at a party congress in Helsinki in November, the Bavarian will be in pole position to replace Jean-Claude Juncker because the EPP is expected to win the most seats in next year's European election.
However, leaders of EU governments have said that legally they cannot be bound by the Spitzenkandidat system, so there is no guarantee that Weber will get the Commission top job.
Weber's main rival for the EPP nod is Alexander Stubb, a former Finnish prime minister who unveiled his campaign plans at a Brussels bar on Wednesday morning.
Other EPP members who have pledged to support Weber include the Dutch Christian Democrats, Greece's New Democracy, and the Slovenian Democratic Party.
The main French conservative party, Les Républicains, has yet to decide whether to back Weber.
But this young guy has never been a head of state or even a minister within any government. Does he really have experience to lead the EU?


text:
Amit Shah, S Jaishankar enter Cabinet Committee on Security
Jun 5, 2019, 6:10 pm IST
Nation, Politics
Defence Minister Rajnath Singh and Finance Minister Nirmala Sitharaman are the other two members of the CCS.
The CCS, which is headed by the prime minister, comprises the "elite four" ministers of the North and South Blocks on the Raisina Hill, consisting of Home, Defence, Finance and External Affairs. (Photo: File)
New Delhi: Home Minister Amit Shah and External Affairs Minister S Jaishankar have been inducted into the Cabinet Committee on Security headed by Prime Minister Narendra Modi, who has reconstituted it after his massive victory in the recent elections.
Defence Minister Rajnath Singh and Finance Minister Nirmala Sitharaman are the other two members of the CCS. They were earlier in the CCS in their capacities as Home and Defence Ministers respectively.
Shah and Jaishankar, who have made their entry into the Union Cabinet, take the place of Arun Jaitley and Sushma Swaraj, who are no longer in the government after they chose not to contest elections on health grounds.
The CCS, which is headed by the prime minister, comprises the "elite four" ministers of the North and South Blocks on the Raisina Hill, consisting of Home, Defence, Finance and External Affairs.
s jaishankar
cabinet committee on security
rajnath singh
Jagan to hand over land records under Bhoo Hakku scheme today


text:
Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C
Takafumi Saito, Masahiro Sugimoto, Kazuo Okumoto, Hiroaki Haga, Tomohiro Katsumi, Kei Mizuno, Taketo Nishina, Sonoko Sato, Kaori Igarashi, Hiroko Maki, Masaru Tomita, Yoshiyuki Ueno, Tomoyoshi Soga
AIM: To clarify the characteristics of metabolite profiles in virus-related hepatocellular carcinoma (HCC) patients using serum metabolome analysis. METHODS: The serum levels of low-molecular-weight metabolites in 68 patients with HCC were quantified using capillary electrophoresis chromatography and mass spectrometry. Thirty and 38 of the patients suffered from hepatitis B virus-related HCC (HCC-B) and hepatitis C virus-related HCC (HCC-C), respectively. RESULTS: The main metabolites characteristic of HCC were those associated with glutathione metabolism, notably 13 γ-glutamyl peptides, which are by-products of glutathione induction. Two major profiles, i.e. , concentration patterns, of metabolites were identified in HCC patients, and these were classified into two groups: an HCC-B group and an HCC-C group including some of the HCC-B cases. The receiver operating characteristic curve for the multiple logistic regression model discriminating HCC-B from HCC-C incorporating the concentrations of glutamic acid, methionine and γ-glutamyl-glycine-glycine showed a highly significant area under the curve value of 0.94 (95%CI: 0.89-1.0, P <0.0001). CONCLUSION: The serum levels of γ-glutamyl peptides, as well as their concentration patterns, contribute to the development of potential biomarkers for virus-related HCC. The difference in metabolite profiles between HCC-B and HCC-C may reflect the respective metabolic reactions that underlie the different pathogeneses of these two types of HCC.
glutamyl-glutamic acid
Logistic Models
γ-glutamyl peptides
Saito, T., Sugimoto, M., Okumoto, K., Haga, H., Katsumi, T., Mizuno, K., ... Soga, T. (2016). Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C. World Journal of Gastroenterology, 22(27), 6224-6234. https://doi.org/10.3748/wjg.v22.i27.6224
Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C. / Saito, Takafumi; Sugimoto, Masahiro; Okumoto, Kazuo; Haga, Hiroaki; Katsumi, Tomohiro; Mizuno, Kei; Nishina, Taketo; Sato, Sonoko; Igarashi, Kaori; Maki, Hiroko; Tomita, Masaru; Ueno, Yoshiyuki; Soga, Tomoyoshi.
Saito, T, Sugimoto, M, Okumoto, K, Haga, H, Katsumi, T, Mizuno, K, Nishina, T, Sato, S, Igarashi, K, Maki, H, Tomita, M, Ueno, Y & Soga, T 2016, 'Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C', World Journal of Gastroenterology, vol. 22, no. 27, pp. 6224-6234. https://doi.org/10.3748/wjg.v22.i27.6224
Saito T, Sugimoto M, Okumoto K, Haga H, Katsumi T, Mizuno K et al. Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C. World Journal of Gastroenterology. 2016 Jul 21;22(27):6224-6234. https://doi.org/10.3748/wjg.v22.i27.6224
Saito, Takafumi ; Sugimoto, Masahiro ; Okumoto, Kazuo ; Haga, Hiroaki ; Katsumi, Tomohiro ; Mizuno, Kei ; Nishina, Taketo ; Sato, Sonoko ; Igarashi, Kaori ; Maki, Hiroko ; Tomita, Masaru ; Ueno, Yoshiyuki ; Soga, Tomoyoshi. / Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C. In: World Journal of Gastroenterology. 2016 ; Vol. 22, No. 27. pp. 6224-6234.
@article{a85bd9f1a57545b8b1afeeb3cae637aa,
title = "Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C",
abstract = "AIM: To clarify the characteristics of metabolite profiles in virus-related hepatocellular carcinoma (HCC) patients using serum metabolome analysis. METHODS: The serum levels of low-molecular-weight metabolites in 68 patients with HCC were quantified using capillary electrophoresis chromatography and mass spectrometry. Thirty and 38 of the patients suffered from hepatitis B virus-related HCC (HCC-B) and hepatitis C virus-related HCC (HCC-C), respectively. RESULTS: The main metabolites characteristic of HCC were those associated with glutathione metabolism, notably 13 γ-glutamyl peptides, which are by-products of glutathione induction. Two major profiles, i.e. , concentration patterns, of metabolites were identified in HCC patients, and these were classified into two groups: an HCC-B group and an HCC-C group including some of the HCC-B cases. The receiver operating characteristic curve for the multiple logistic regression model discriminating HCC-B from HCC-C incorporating the concentrations of glutamic acid, methionine and γ-glutamyl-glycine-glycine showed a highly significant area under the curve value of 0.94 (95{\%}CI: 0.89-1.0, P <0.0001). CONCLUSION: The serum levels of γ-glutamyl peptides, as well as their concentration patterns, contribute to the development of potential biomarkers for virus-related HCC. The difference in metabolite profiles between HCC-B and HCC-C may reflect the respective metabolic reactions that underlie the different pathogeneses of these two types of HCC.",
keywords = "Glutathione, Hepatocellular carcinoma, Metabolome, Oxidative stress, γ-glutamyl peptides",
author = "Takafumi Saito and Masahiro Sugimoto and Kazuo Okumoto and Hiroaki Haga and Tomohiro Katsumi and Kei Mizuno and Taketo Nishina and Sonoko Sato and Kaori Igarashi and Hiroko Maki and Masaru Tomita and Yoshiyuki Ueno and Tomoyoshi Soga",
T1 - Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C
AU - Saito, Takafumi
AU - Sugimoto, Masahiro
AU - Okumoto, Kazuo
AU - Haga, Hiroaki
AU - Katsumi, Tomohiro
AU - Mizuno, Kei
AU - Nishina, Taketo
AU - Sato, Sonoko
AU - Igarashi, Kaori
AU - Maki, Hiroko
AU - Tomita, Masaru
AU - Ueno, Yoshiyuki
AU - Soga, Tomoyoshi
N2 - AIM: To clarify the characteristics of metabolite profiles in virus-related hepatocellular carcinoma (HCC) patients using serum metabolome analysis. METHODS: The serum levels of low-molecular-weight metabolites in 68 patients with HCC were quantified using capillary electrophoresis chromatography and mass spectrometry. Thirty and 38 of the patients suffered from hepatitis B virus-related HCC (HCC-B) and hepatitis C virus-related HCC (HCC-C), respectively. RESULTS: The main metabolites characteristic of HCC were those associated with glutathione metabolism, notably 13 γ-glutamyl peptides, which are by-products of glutathione induction. Two major profiles, i.e. , concentration patterns, of metabolites were identified in HCC patients, and these were classified into two groups: an HCC-B group and an HCC-C group including some of the HCC-B cases. The receiver operating characteristic curve for the multiple logistic regression model discriminating HCC-B from HCC-C incorporating the concentrations of glutamic acid, methionine and γ-glutamyl-glycine-glycine showed a highly significant area under the curve value of 0.94 (95%CI: 0.89-1.0, P <0.0001). CONCLUSION: The serum levels of γ-glutamyl peptides, as well as their concentration patterns, contribute to the development of potential biomarkers for virus-related HCC. The difference in metabolite profiles between HCC-B and HCC-C may reflect the respective metabolic reactions that underlie the different pathogeneses of these two types of HCC.
AB - AIM: To clarify the characteristics of metabolite profiles in virus-related hepatocellular carcinoma (HCC) patients using serum metabolome analysis. METHODS: The serum levels of low-molecular-weight metabolites in 68 patients with HCC were quantified using capillary electrophoresis chromatography and mass spectrometry. Thirty and 38 of the patients suffered from hepatitis B virus-related HCC (HCC-B) and hepatitis C virus-related HCC (HCC-C), respectively. RESULTS: The main metabolites characteristic of HCC were those associated with glutathione metabolism, notably 13 γ-glutamyl peptides, which are by-products of glutathione induction. Two major profiles, i.e. , concentration patterns, of metabolites were identified in HCC patients, and these were classified into two groups: an HCC-B group and an HCC-C group including some of the HCC-B cases. The receiver operating characteristic curve for the multiple logistic regression model discriminating HCC-B from HCC-C incorporating the concentrations of glutamic acid, methionine and γ-glutamyl-glycine-glycine showed a highly significant area under the curve value of 0.94 (95%CI: 0.89-1.0, P <0.0001). CONCLUSION: The serum levels of γ-glutamyl peptides, as well as their concentration patterns, contribute to the development of potential biomarkers for virus-related HCC. The difference in metabolite profiles between HCC-B and HCC-C may reflect the respective metabolic reactions that underlie the different pathogeneses of these two types of HCC.
KW - Glutathione
KW - Hepatocellular carcinoma
KW - Metabolome
KW - Oxidative stress
KW - γ-glutamyl peptides


Hi, my name is Marci I am a college student. I have over 5yrs experiance as a babysitter/nanny. I am infant/child CPR and First Aid certifed. I also have exxcellent references upon request. I am avalible at your home or mine.


text:
Cancer overrides the circadian clock to survive
by Medical University of South Carolina
Hollings Cancer Center researchers Dr. Yiwen Bu and Dr. J. Alan Diehl explore how cancer overrides the circadian clock to survive. Credit: Hollings Cancer Center
Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) find. A key part of the circadian clock opposes this process, according to a paper published online Dec. 11 in Nature Cell Biology.
For tumors to grow and spread, cancer cells must make larger than normal amounts of nucleic acids and protein, so they can replicate themselves. Yet in both normal and cancer cells that increase their synthesis of protein, a small percent of those proteins do not fold properly. When that happens, the cell activates its unfolded protein response (UPR), which slows down the making of new proteins while the misfolded proteins are refolded. Eventually, the buildup of misfolded proteins becomes toxic and leads to cell death. However, cancer cells have learned to use the UPR to slow protein synthesis when needed, in order to handle the backlog of misfolded proteins. This helps them survive in conditions that would kill normal cells.
This pattern of adaptation is often seen in tumor cells, according to J. Alan Diehl, Ph.D., the SmartState Endowed Chair in Lipidomics, Pathobiology and Therapy at the MUSC Hollings Cancer Center and senior researcher on the project. "What a tumor cell is doing is taking a pathway that's already in the cell and using it to its advantage," said Diehl.
Yet it was not clear exactly how cancer cells were able to use UPR activity to influence circadian rhythm. Diehl's group found that the UPR and circadian rhythm are linked together to lead the clockwork of the cell and also that cancer cells use the UPR to manipulate the circadian clock in ways that allow them to survive conditions that are toxic to normal cells.
To start, Diehl and his fellow researchers formulated a new idea based on what was known about protein synthesis in the cell. First, as they knew, the UPR is altered in tumors, and second, cells establish a circadian rhythm to regulate metabolism by producing levels of certain proteins that rise and fall in coordination with natural cycles of light and dark. Third, other scientists had observed that circadian rhythm is altered in tumor cells. Since protein production is tied to circadian rhythm, Diehl's group asked if misfolded proteins might change circadian rhythm in cancer cells.
In their first set of experiments, Diehl's research team used chemicals to activate the UPR in osteosarcoma cells. They found that, when activated, the UPR changes levels of an important protein called Bmal1, which is a transcription factor that rises and falls with cycles of light and dark. As it does, it regulates the expression of major circadian rhythm genes. When cells were exposed to cycles of light and dark, Bmal1 levels peaked during dark hours. But when the UPR was chemically activated, Bmal1 stayed low during both light and dark phases, which caused a phase shift in the expression of circadian genes. When one of the main parts of the UPR machinery was absent in cells, the phase shift did not happen.
Next, the group found that the UPR functions much like a "middleman" between light-dark cycles and the ability of cells to establish a circadian rhythm from those cycles. Levels of the circadian protein Bmal1 continued to decrease, as the UPR was increasingly activated. In rodents that had their light-dark cycles suddenly reversed, Bmal1 stopped rising and falling - a clear sign that their circadian rhythms were disrupted. Shifts in light exposure activated the UPR in those rodents' cells.
But what does that mean for the development of cancer?The team found that patients with breast, gastric or lung cancers survived longer when they had higher levels of Bmal1 protein. In myc-driven cancers, the UPR was causing the loss of Bmal1 protein, which caused the tumors to grow. Myc-driven tumors lost circadian rhythm, whereas normal cells maintained it. Conversely, high levels of Bmal1 overtook the UPR, thereby allowing protein synthesis to continue, which was toxic to tumor cells. In this way, Bmal1 directly encourages protein synthesis.
This is the first study showing that human cancer suppresses circadian rhythm by controlling protein synthesis through Bmal1. Cancer cells survived longer by using the UPR to suppress Bmal1 and short-circuit their circadian rhythms. These results are important for human biology, according to Yiwen Bu, Ph.D., a postdoctoral scholar in Diehl's laboratory and first author on the paper. "Every single normal cell in our body has circadian oscillation," said Bu. "We showed that resetting the circadian rhythms in cancer cells slows down their proliferation."
Still, do changes in light-dark cycles contribute to the development of cancer in humans? It is not yet clear in patients if circadian shifts contribute to changes in the UPR and if that, in turn, contributes to the development of cancer. But these results could help clinicians boost the effectiveness of current cancer treatments, Diehl said.
"Physicians are beginning to think about timing delivery of therapies in such a way that, say, if we deliver a drug at a certain time of day, we'll get better on-target effects on the cancer and less toxicity in the normal cells," he said.
Time matters: Does our biological clock keep cancer at bay?
More information: Yiwen Bu et al, A PERK–miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival, Nature Cell Biology (2017). DOI: 10.1038/s41556-017-0006-y
Journal information: Nature Cell Biology
Provided by Medical University of South Carolina
Citation: Cancer overrides the circadian clock to survive (2017, December 28) retrieved 16 July 2019 from https://medicalxpress.com/news/2017-12-cancer-overrides-circadian-clock-survive.html
Potassium is critical to circadian rhythms in human red blood cells
Link between biological-clock disturbance and brain dysfunction found
New study reveals a link between circadian clock disruption and tumor growth
Cancers don't sleep: The Myc oncogene can disrupt circadian rhythm
Cancer doesn't sleep: Myc oncogene disrupts clock and metabolism in cancer cells
People who microdose psychedelic substances report improved mood and focus
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text:
Higbee Street School is located in Trenton, Mercer County, New Jersey, United States. The building was built in 1857 and was added to the National Register of Historic Places on April 14, 1995.

See also
National Register of Historic Places listings in Mercer County, New Jersey

References

Buildings and structures in Trenton, New Jersey
National Register of Historic Places in Trenton, New Jersey
School buildings completed in 1857
School buildings on the National Register of Historic Places in New Jersey
New Jersey Register of Historic Places
1857 establishments in New Jersey

redpajama_set_name: RedPajamaWikipedia


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text:
import React, { Component, PropTypes } from 'react';
import TextField from 'material-ui/TextField';
import FieldTitle from '../../util/FieldTitle';

/**
 * An Input component for a string
 *
 * @example
 * <TextInput source="first_name" />
 *
 * You can customize the `type` props (which defaults to "text").
 * Note that, due to a React bug, you should use `<NumberField>` instead of using type="number".
 * @example
 * <TextInput source="email" type="email" />
 * <NumberInput source="nb_views" />
 *
 * The object passed as `options` props is passed to the material-ui <TextField> component
 */
export class TextInput extends Component {
    handleBlur = (eventOrValue) => {
        this.props.onBlur(eventOrValue);
        this.props.input.onBlur(eventOrValue);
    }

    handleFocus = (event) => {
        this.props.onFocus(event);
        this.props.input.onFocus(event);
    }

    handleChange = (eventOrValue) => {
        this.props.onChange(eventOrValue);
        this.props.input.onChange(eventOrValue);
    }

    render() {
        const {
            elStyle,
            input,
            label,
            meta: { touched, error },
            options,
            resource,
            source,
            type,
        } = this.props;

        return (
            <TextField
                {...input}
                onBlur={this.handleBlur}
                onFocus={this.handleFocus}
                onChange={this.handleChange}
                type={type}
                floatingLabelText={<FieldTitle label={label} source={source} resource={resource} />}
                errorText={touched && error}
                style={elStyle}
                {...options}
            />
        );
    }
}

TextInput.propTypes = {
    addField: PropTypes.bool.isRequired,
    elStyle: PropTypes.object,
    input: PropTypes.object,
    label: PropTypes.string,
    meta: PropTypes.object,
    name: PropTypes.string,
    onBlur: PropTypes.func,
    onChange: PropTypes.func,
    onFocus: PropTypes.func,
    options: PropTypes.object,
    resource: PropTypes.string,
    source: PropTypes.string,
    type: PropTypes.string,
    validation: PropTypes.object,
};

TextInput.defaultProps = {
    addField: true,
    onBlur: () => {},
    onChange: () => {},
    onFocus: () => {},
    options: {},
    type: 'text',
};

export default TextInput;

redpajama_set_name: RedPajamaGithub


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AXIS Capital Restricts Fossil Fuels Underwriting
AXIS and Chubb join a growing list of insurance companies that say they will limit underwriting capital allocation and investments in fossil fuels projects.
By: Dan Reynolds | October 18, 2019
Topics: Environmental | Future of Insurance | Insurance Industry
The Bermuda-based insurer AXIS Capital Holdings Limited announced on Oct. 16 that it will devote less capital to underwriting projects involving the mining or burning of fossil fuels.
In doing so, it becomes the latest in a growing number of insurers, including global giants Swiss Re, Munich Re, Chubb and AXA, to restrict their support of energy sources that scientists say are contributing to climate change.
Rising seas and increasingly intense storms in recent years due to global warming have gotten the attention of many insurers. It is becoming increasingly common for carriers to come out with statements and positions outlining how they plan to assist their risk partners in transitioning to a low-carbon economy.
In its October 16 release, AXIS outlined several new stances:
That it will not provide new insurance or facultative reinsurance of new thermal coal plants or mines and their dedicated infrastructure; or oil sands extraction and pipeline projects and their dedicated infrastructure; or to companies that generate 30% or more of their revenues from thermal coal mining, generate 30% or more of their power from thermal coal or hold more than 20% of their reserves from oil sands.
Renewals will be considered on a case-by-case basis until January 1, 2023. Exceptions to this policy may be considered on a limited basis until January 1, 2025 in countries where sufficient access to alternative energy sources is not available.
In the area of investments, AXIS will not make new investments in companies that generate 30% or more of their revenues from thermal coal mining, that generate 30% or more of their power from thermal coal, or that hold 20% of their reserves in oil sands.
"We believe that insurers have an important role to play in mitigating climate risk and transitioning to a low-carbon economy," said AXIS president and CEO Albert Benchimol, as quoted in the AXIS release.
Read More: It's Long Past The Time for Banks and Insurers to Unfriend Coal. Here's Why
"This policy is in line with our broader strategies such as reducing investments in lines that do not align with our long-term approach; investing in growth areas, such as renewable energy insurance, where we are a top-five global player; and growing our corporate citizenship program, a core focus of which is creating a positive environmental impact," he added.
"We strive to ensure that every business decision we make is guided by our corporate values, and we believe this new thermal coal and oil sands policy is the right thing to do for our planet and our business," added AXIS General Counsel Conrad Brooks.
As AXIS takes it stand, the Los Angeles Times reported this week on the decline in coal mining sector employment.
The October statement from AXIS follows the issuance of a fossil fuels policy by Zurich-based Chubb in July 2019. In that statement, Chubb announced:
Chubb will not underwrite risks related to the construction and operation of new coal-fired plants. Exceptions to the policy will be considered until 2022 in regions that do not have practical near-term alternative energy sources and taking into account the insured's commitment to reduce coal dependence.
Chubb will not underwrite new risks for companies that generate more than 30% of their revenues from thermal coal mining. Chubb will phase out coverage of existing risks that exceed this threshold by 2022.
Chubb will not underwrite new risks for companies that generate more than 30% of their energy production from coal. Chubb will phase out coverage of existing risks that exceed this threshold beginning in 2022, taking into account the viability of alternative energy resources in the impacted region.
"Chubb recognizes the reality of climate change and the substantial impact of human activity on our planet," the company said in its July statement.
"Chubb expects a transition over time to a greater reliance on alternative and renewable fuel solutions to meet energy needs," the company added. &
Dan Reynolds is editor-in-chief of Risk & Insurance. He can be reached at [email protected]
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By: AIG | December 21, 2020
The renewable energy sector looks poised to continue its years-long growth trajectory. Falling technology costs, availability of tax credits, rising consumer demand and an urgent need to mitigate greenhouse gas emissions to combat the effects of climate change have all driven interest and investment dollars to wind, solar and battery storage projects.
This growth has continued despite uncertainties introduced by the COVID-19 pandemic. A market outlook report by Deloitte states that as energy demands dropped in the spring amid state shutdowns, the share of energy produced from wind and solar plants actually increased by 2%.
"Renewable energy sources beat coal in the generation mix for 116 days" as of June, compared to just 39 days over the same period last year, according to the report. This demonstrates grid resiliency and reliability — two primary concerns with the scalability of renewable energy projects.
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Ian Kirejczyk, Property Underwriter – Energy and Construction at AIG Contact: 770-671-2214 / [email protected]
The demand for more renewable energy has resulted in bigger projects, which require more space.
For that reason, wind, solar and battery storage projects are increasingly sited in remote areas in states that have more available land — mostly Midwest and Southwestern states that are also more vulnerable to natural hazards like wildfire, hail and tornado.
"As new projects are being built, they're being built in remote areas, and we're definitely starting to see some of those more catastrophic losses from hail, wind, flooding and wildfire events that impact the ability to access project sites, which can impact maintenance schedules or delay repairs and in turn can result in increased claim costs," Kirejczyk said.
Advancements in drone technology have alleviated this slightly by allowing for remote loss assessments when physical inspections aren't feasible, but increased exposure to natural hazards and roadblocks to a quick recovery will remain challenging as renewable energy projects expand into new territory.
2) Increased repair and replacement costs on large projects
Bigger projects also mean increased exposure to equipment failure.
"These units are growing in size and scale. When wind turbines were first commissioned, they were 225 kilowatts and now are pushing five megawatts, from an onshore wind perspective. Offshore, they're even larger. As the technology has matured, we are seeing a decline in the cost of manufacturing, but an increase in the cost of the repairs. This can be attributed to more complex designs and engineering making repairs more costly," Kirejczyk said.
According to 2019 research by Wood Mackenzie Power & Renewables, a research and consulting firm, the global onshore wind industry spent roughly $8.5 billion on unplanned repairs for component failures, representing 57% of all operations and maintenance costs.
"Unplanned failures can cost the asset owner as much as $30,000 per turbine per year in terms of repairs and spare parts and up to 7 days' worth of lost production per year. … Capital components alone — gearboxes, generators and blade — can cost up to $10,000 per turbine per year in replacements," according to the firm's report.
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Captive funding abilities can also support larger owners who want to insure more of their risk themselves, but need assistance unlocking their captives' capabilities. "That's where AIG can partner with them and take a different approach instead of the traditional risk transfer property contract. The renewable energy space is poised for change and some clients who have captives may look at utilizing them as a means for risk transfer, which is an area in which we specialize and can offer our expertise," Kirejczyk said.
As the world moves toward a future powered by renewable energy, companies need both reliable insurance coverage and risk management solutions to address their exposures and continue growing sustainably.
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To learn more, visit https://www.aig.com/business/industry/energy.
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text:
45 The Fugitive Life of Kulalalaka 4
Champagne Akemakri's memory flashes back then as soon as he sees Coolaraka rolling into the abandoned house.
Gianjanbari had once harassed an audience who did not support the brave Zepuros in "Going with Master Zepuros, The Immortal King's Country Tour" for not selling lunch lunches.
"Oh, wow! Speaking of wild dogs, leftover clams Bye! That's why we're gathering in such a dumpster, if we like. Huh! One of these days I'm gonna stick my face in that garbage pile, and to start doing gasagoso, it's gotta be, uh-huh!
and other wild dog-side audiences, I was mocking......
That's what Kulalalaka said to the security staff gathered to break in and seize him in the carriage.
'Supplies! I brought lunch for the wild dogs!
At this time she was wearing a wild dog mask and hiding her face, but only that voice, I still remember clarity
And good thing she doesn't know her face, she keeps making fun of herself.
"I received a secret order from one of you, and I arrived here faster on a horse than Hurlberry, the king! How dare you capture me!
'Look! This event has as many as a thousand spectators! Everything you've done here today has been brought home as a souvenir story and rumored to spread throughout the country! Can't you understand that it's only bad reviews, such as pointless food attacks, that don't do us any good!
"It is only by sending salt to our enemies to win that our feat name will roar all over the country...! That's what they want! That's why I do wild dog masks and stuff on purpose!
I asked who 'that one' was, but they gave me a response that made me include, and I misconstrued that Djangian Bali was my employer, the brave Genocide Lower's.
I should have taken more suspicion if I had, but I was barely pressured by her grand hat......
Janjan Bali has allowed lunch distributions to the wild dog side.
The lunch box was, to be honest, brilliant enough to make me want to eat the fat giant burr of my tongue as well.
Now that I think about it, I even feel like that lunch case has become a decision hit for event failure.
In the end, the tour ended in great failure and Djangian Bali made a bitter choice to return alive.
"Ohhhh! The punishment for heckling braves, even if you break 500 rounds, still won't stop. Ahhhhhhhh! We're all gonna get rid of that evil brave guy like this. Ahhhhhhhhh! Janjang, Ballyyyyyyyyyy!!
Sage the brave Zepuros that should have to be lifted...!
"Janjang, Ballyyyyyyyyyy!! Gold's the best hero out there today. Ahhhhh! Guys, applause and cheer!
I'm bald of a wild dog that was supposed to be derogatory...!
The humiliation of that time, I will still remember.
And the moment Kulalalaka took the mask, Ten Himself who made that kick......!
Shaking his long dark hair, the sweat of the balls floating on his brown skin, sparkling......!
Here's what she said...!
"Phew...! Your MC is doing quite well...! Not yet to be exclusive to Slumdog Mart......!
Gianjan Bali, preferred by brown women, was, in fact, only occasional for a moment.
But in the aforementioned dialogue, ruined......!
"Uhhhhhhh!? Impossible. Impossible. Impossible!? Impossible. Ahhhhhhhhh!? Using words as a weapon, it's impossible for me to ever be... beaten by words, and the employees at the shop at the end of the day, to be blindfolded from the top. JAHHHHHHHHHHHH!?!?
It caused him great humiliation and frustration when he became a charismatic host in a rough wave called the brave entertainment industry.
Maybe if it weren't for one of her words, I would have forgotten everything with my usual texture.
You may or may not have traveled on a heartbreak trip to Greysky Island.
And... I may or may not have been caught in various ways by rampant horses and forced to live in extreme poverty...
But now the chain of destiny is one.
He was sure.
God gave this to himself, and he said it was a test...!
He said he was destined to reunite with her ahead of the trials...
To make the restoration of the former vengeance and of the glory fulfill at the same time......!
Again, God made them look alike...!
It goes without saying that the prince who was chased after the country has overcome various trials, which are good for the people….
Take the Holy Sword (Afro), which is the testimony of the king, and defeat the wicked witch (Kulalalaka) and become king...
Later as a legend and told to future generations, it was one page of your species Drifting Tan "Kishi Hikaru"...!
Janjan Balibari generously entertained the bad witch to avoid being enlightened by the surprise of the reunion.
He seemed to have been chased by Shinsengumi, but he got rid of him with a good mouthpiece.
I was a little thrilled when she asked me her name, but I seemed to believe the pseudonym Champagne Akemakri.
And she was completely relieved and fell into a deep sleep, as if she had spoken poisonous apples...
It was also the moment when we finally got what had long been interrupted.
The turn of the wild dog that had been going on since the time of the Immortal King's Country Tour came to an end, and finally the turn of the Djangian Bali......!
Janjan Bali Bali, no, now Champagne Akemakri, put a dog ear and tail of the thing on her sleeping.
And take charge and head straight to the best casino on this island......!
"I have a good wild tail! Hang on to" Narrow Roulette, "and you'll have the best balls to see what you're after! If you let me do tonight's MC, Jean Jean... No, I'll let Champagne Akemakri make you some money!
Like a couple of street performers, I sold them in...!


text:
Giousouf is a surname. Notable people with the surname include:

 Aichan Kara Giousouf (born 1963), Greek politician
 Cemile Giousouf (born 1978), German-Greek politician


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The CD contains an easy to use browser which makes locating and selecting an image easy. Also included is a printed reference and PDF files allowing you to print more if required!


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Prem was delighted that 14 Portsoken residents and community champions were able to join him and watch the installation from the public gallery. After the ceremony, The Lord Mayor Alderman Charles Bowman, Sheriff Alderman Tim Hailes and former Lord Mayor Alderman Sir David Wootton greeted the resident and said they were extremely happy to have them there.
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On December 22, up to 4,000 nurses who work for the Sutter Corporation are going on strike, protesting against sweeping cuts in healthcare coverage and patient care protections, according to the California Nurses Association/National Nurses United.
Almost 2,000 nurses at Long Beach Memorial, a major hospital in Southern California, will join in the strike, protesting at the proposed reduction in health coverage for nurses, as well as putting off concerns regarding patient care.
A possible strike was averted at Marin General Hospital, Greenbrae (a former Sutter hospital), the California Nurses Association announced, after a contract settlement was agreed. The agreement is being put to a vote by nurses this week, and followed a decision by negotiators representing the hospital to withdraw demands similar to those imposed by Sutter corporation.
The Sutter Corporation has made over $3.7 billion in profits over the last six years, the CNA informs. Another work stoppage occurred in September this year, triggered by almost 200 demands for major alterations to contracts.
The gist of the California Nurses Association announcement yesterday was that Sutter hospitals are cash rich and should not be demanding reductions in contracts and patient care.
"Sutter Health's demands at the bargaining table have forced nurses to strike, because they're unreasonable and would negatively affect patient care. We are nurses and must stand up for our patients and the good of our communities."
Black says that since the strike, there have been numerous meetings with Sutter management officials, and very little progress. She says Sutter continues with demands for cuts that would undermine safety standards and make even more money for the company, with barely any advantages for patients.
"System-wide, more than 150 takeaway demands remain on the table, nearly 100 at Alta Bates Summit alone.
The nurses union says that Sutter is relentlessly pushing for changes that would make it very hard for nurses to properly advocate for patients against the budget-focused priorities of the company's management. Nurses will effectively be forced to work when they are ill, exposing their pathogens to patients, some of whom are extremely ill.
"Sutter's proposal to eliminate sick leave will force nurses to come to work sick which will further jeopardize our fragile patients."
"Sutter's proposal to eliminate charge nurses threatens high-quality patient care and our ability to maintain patient safety and to advocate for our patients."
The company is not strapped for cash; it has $11.6 billion in assets and pays its top 20 executives over $1 million annually. None of these executives, the union writes, provides bedside care.
"We told our management that we would pledge not to strike if they pledged to not put takeaways on the table. They would not make that commitment. They are the ones who are forcing us into this situation. We must stick together to fight on behalf of our standards and our patients."
"Nurses will not be silent when corporations like Sutter demonstrate they care more about their budgets and Wall Street portfolios than they do about assuring the highest quality of care for their patients, and keeping experienced, professional RNs at the bedside. Every nurse, just like every American, deserves quality healthcare, and should not be threatened with high costs for basic coverage that threatens the health security of their families."
"We staunchly refuse to be silenced on patient care protections. As nurses, we speak up, and we insist on standards that safeguard our patients, but Sutter doesn't want to hear about anything that might cut into their huge profits."
The nursing union says Sutter hospital nurses have complained of the lax workplace safety standards at their hospitals. After a nurse was assaulted at the Oakland Alta Bates Summit campus, the company will not upgrade safety procedures for patients and nurses - procedures the nurses had put forward.
"Sutter executives are awarding themselves lavish compensation packages while they cut services to the community and demand sacrifices from the nurses. We have to strike."
Nordqvist, Christian. "Up To 4,000 Nurses To Strike, Says Nursing Union, California." Medical News Today. MediLexicon, Intl., 11 Dec. 2011. Web.