A new Fox Chase Cancer Center study suggests men with early stage prostate cancer treated with radiation therapy should begin hormone therapy immediately if their PSA level rises quickly and doubles within six months at any time after treatment. The study also supports foregoing hormones if the PSA doesn't rise as quickly. Both findings suggest a change in the practice of prescribing hormones is warranted.
After treatment for prostate cancer, many men will experience fluctuations or bounces in their PSA level, but for some the PSA continues to rise and doesn't return to its lowest point immediately after treatment. Knowing if or when to recommend hormone treatment (androgen deprivation therapy) depends on how much and how quickly the PSA rises – called the PSA doubling time. Hormone therapy has been shown to kill cancer cells and improve survival, but it carries a risk of side effects.
"We've been using PSA doubling time to help guide our decision about when to begin hormone therapy, but this study gives us new and critical information that suggests we should start therapy sooner than previously thought for some patients and delay treatment for others," explains Eric Horwitz, M.D., acting chairman and clinical director of the radiation oncology department at Fox Chase, who led the study. "While hormone therapy can have side effects such as hot flashes, decreased libido and osteoporosis, it can help prevent the cancer from spreading to the bones, causing pain and leading to an earlier death from the disease."
Previous studies indicated an increased likelihood that the cancer had spread if the PSA doubling time occurred within 12 months, and thus a potential benefit from receiving hormone therapy. But recently, a newly validated formula, known as the Phoenix definition, used by physicians demonstrates a more accurate way of determining biochemical failure, a term used to describe a significant rise in PSA. Using the new formula, the Fox Chase team was able to determine when earlier action needs to be taken.
"What we now know is that when the PSA rises and doubles within 6 months, versus 12 months, we need to act," explains Horwitz. "Our study suggests that these are the men who will benefit most from hormone therapy." Horwitz's research was presented today at the 50th annual meeting of the American Society for Therapeutic Radiology and Oncology.
Also, Horwitz says the study helps identify who is less likely to benefit from hormone therapy which may indicate a necessary change in current practice.
"Men whose PSA rises, but does so over a longer period of time may not benefit from hormones.
"These results further refine the role of PSA doubling time in predicting which patients may benefit from hormone therapy and which patients may be observed expectantly and spared the toxicity of the hormones," Horwitz concludes.


Replicas of Nikon's very first binoculars, but updated with modern lenses, prisms and coatings for superb brightness and resolution. Ultra compact and lightweight (only 135g). Short close-focus distance : 2 m. Multilayer coated lenses for bright images.


text:
Home | World | Africa | 'Health budget big, but inadequate'
'COVID-19 hit the blood bank hard'
Churches demand seat in Parliament
'Health budget big, but inadequate'
ZIMBABWE'S health budget allocation has been dismissed as grossly inadequate to tackle the myriad of challenges besetting the sector.
Finance minister Mthuli Ncube allocated the health sector $54,7 billion, constituting 13% of his $429 billion budget in the 2021 National Budget presented in Parliament on Thursday.
Although health was allocated the biggest vote, stakeholders have said the amount was inadequate to clean up the mess in the sector.
Most public health facilities are operating on shoe-string budgets with barely meet the minimum tools required to give quality healthcare.
Commenting on the budget allocation the Zimbabwe Nurses Association (Zina) president Enock Dongo said the 13% fell short of the situation on the ground.
"They should have tried for 15% as agreed by the Abuja Declaration. We appended our signature to this and must honour it," Dongo said.
In April 2001, the African Union member States met and pledged to set a target of allocating at least 15% of their annual budget towards health.
Dongo said the advent of the COVID-19 pandemic has also made the health delivery system worse and this required substantial funding to address the challenges.
"Unless there is going to be a separate budget for COVID-19," he said.
He said another concerning issue was the actual release of the funds.
Community Working Group on Health (CWGH) executive director Itai Rusike said the budget allocation to the health sector is below the level required for the delivery of quality health services.
He questioned if the allocation had increased in real terms if compared to other years.
Many Zimbabweans are failing to access health services due to regular increases in essential drug costs and hospital costs.
Citizens Health Watch (CHW) said while they welcomed the increase in health allocation, but was however concerned with the unsubstantiated claims regarding reforms in the sector as foundation for the budgeting.
"A clear audit of the claims should be made. The renovations being celebrated are of little value without personnel and medicines in the respective facilities," said Fungisayi Dube, from CHW.
"We welcome the increased budget on refurbishment and procurement but measures should be put in place that resources are utilised accordingly as the health sector has been embroiled in corruption scandals."
Meanwhile, teachers have slammed Ncube's budget, describing it as "high sounding nothing with no educational traction".
Ncube allocated $55 billion to the Primary and Secondary Education, which translates to 12,8% of the budget.
Teachers said the allocation fell short of the 22% agreed under the Dakar Framework.
"Against the Dakar Framework that calls for a budget of primary and secondary education above 22% of the national budget, Minister Ncube has only allocated $55,221 of $429,341 billion, which is only 12,8%," Progressive Teachers Union of Zimbabwe president Takavafira Zhou said.
"Fundamentally, minister's budget is still rooted in austerity for prosperity of the elites, which austerity would continue to reward teachers with poverty."
Zhou added: "It is against this background that as educators we are worried by the celebratory mood by some parliamentarians over this allocation."
Zhou said the $55 billion could not address the teacher's salary grievances and let alone cater for the demands of 9689 schools for some infrastructural development, more than 6,5 million students, 135 000 teachers and a deficit of 50 000 teachers.
Juventus star Ronaldo is now tied for most official goals in football history

redpajama_set_name: RedPajamaCommonCrawl


Two days, hands on shooting and testing with a Dragon Sensor RED EPIC camera by award winning Australian TVC Director Mark Toia and it's no wonder the opening shot is eye opening… There is no mistake about the quality.
RED EPIC DRAGON – ITS THE REAL DEAL ! from Mark Toia on Vimeo.
But there is still noise, but nothing like before. I ran some 250d 2k film rushes next some of my 4000asa stuff, And silly as it sounds, it looks like film grain, not noise. Don't ask me how, as I wouldn't have a clue. But it looks great !
Single still frames compared to a top of the line professional 35mm Digital stills cameras, I'm going to say that the EPIC matches, if not betters most. Don't ask me how they do it, but every single frame from the DRAGON is 109meg !! @16bit when saved as a tiff from RCX. and at 100 Frames per second, I tell you this… someone has sold there sole to the devil.
If you are a pro photographer, you are mad if you don't have this camera in your tool box. You quite literally will never miss a single shot.
The Dragon is more stable than my current MX EPIC's.
The SONY F65 I rate as having the best sensor in the market for a production cine camera. Yes.. it's better than the EPIC- MX. (I'm not going to harp on about the size of it or the price comparisons).
All the F65 SONY purists out there will dispute this. But I have Sony files here with me, and I'm looking at both side by side… and Dragons grain (noise) structure is cleaner and it has more range.
Dragon is now the King. (AND… I'm not going to harp on about the size of it or the price comparisons). or did I ..ha !
It's the first camera ever that I have used that captures exactly what I see with my own eye.
and Jim Jannard on the combination and quality of using Leica lenses with a Dragon sensor equipped RED camera.
I have to say they we have tested just about every combination of lenses with the Dragon sensor and the Leicas win.
This really should be no surprise.
All the Leicas cover the full sensor and have the most resolution of all lenses tested.
While some lenses will necessitate dropping down to 5.5K to cover… the Leicas don't. The resolution of these lenses are completely matched with the Dragon sensor.
Of course all other lenses will work at 5K-6K with varying results. And no matter what you use you get the dynamic range advantage of the Dragon. The Leicas are just the best of the best.
and when asked if you could still get amazing results using master primes at 6k?
Yes… absolutely. And at 6K.
You will also get great results with Ultra Primes at 5.5K. And good results with Canon and Nikon mount lenses at 6K.
I am just talking the best of the best.
for more information about the RED EPIC Dragon Sensor and Leica lens conversation hit up REDuser.


It has been said, "The Evil" can use a lost soul to feed their own, extending their physical being indefinitely.
All through the ages of time, man has struggled to keep balance of mind, body and spirit.
These three chattels together create a whole being. Take one away…the two remaining fail to flourish. In the depth of turmoil, the soul and being have been known to part.
He is waiting for you!
How was your experience at Evil Falls?
Is this information incorrect or outdated? Please let us know! Submit updated info here.


text:
La Grande Convention est l'un des textes fondamentaux régissant, dans l'univers de fiction de Dune de Frank Herbert, les rapports politiques constitutionnels du tripode du pouvoir Empereur/Landsraad/Guilde spatiale (Le Bene Gesserit n'ayant officiellement qu'un rôle de conseil).

Elle organise les relations entre Maisons, et entre ces dernières et le Trône du Lion d'Or, propriété de la Maison Corrino jusqu'à la prise du pouvoir par Paul Atréides.

Elle proscrit notamment l'usage d'atomiques par une Maison contre une autre, exigence rendue nécessaire à la suite des carnages et destructions massives que ces armes provoquèrent lors de guerres civiles entre Maisons.
La Grande Convention, en encadrant les guerres entre les Maisons du Landsraad, tend aussi à éviter les dommages collatéraux pour protéger les populations civiles non combattantes.

Elle contient en outre deux prohibitions majeures : l'interdiction de fabriquer des machines pensantes, et l'interdiction de l'utilisation d'armes bactériologiques. Ces deux tabous sont issus du Jihad Butlérien avec la guerre des Hommes contre les machines, et la Peste robotique employée par Omnius.

Paul Atréides fut accusé par l'Empereur Padishah Shaddam IV d'avoir violé la Grande Convention en 10193, lors de son offensive sur Arrakeen, où étaient stationnés les troupes Sardaukars de l'Empereur et les contingents des Grandes Maisons, venus sur Arrakis pour abattre Muad'Dib afin que l' (selon la formule consacrée de la Guilde spatiale).
Muad'Dib se défendit de cette accusation en argüant du fait qu'il n'avait utilisé les atomiques de la Maison Atréides que pour détruire le Mur du Bouclier, chaîne de montagnes d'Arrakis, afin de se porter à la rencontre de l'Empereur qui l'avait convoqué. Il justifia cela par la nécessaire célérité que devait manifester un loyal sujet lorsque son Empereur le convoquait.
Ce détournement de la Grande Convention est l'une des clefs de la victoire de Muad'Dib et de ses Fremen, qui conduisit à la suprématie galactique de la Maison Atréides.

Lexique de Dune

redpajama_set_name: RedPajamaWikipedia


These position statements are intended for use by ABC member clubs and by ABC members to address community issues or unfavorable canine legislation at the local level. These statements are in line with the ABC Code of Ethics and with positions supported by the American Kennel Club. Permission is granted by ABC to use these statements and the information contained in these statements with local media or with local politicians to help explain the ABC's position on these important issues.
The American Boxer Club recognizes the long history of the human-canine bond, and supports caring and responsible dog ownership as a celebration of that bond. Dog ownership provides people with both psychological and health benefits, and opens the door to a deeper connection with an understanding of all animals. Responsible dog ownership requires a commitment for the life of the dog. This takes time, patience, and training in order to insure that a puppy will grow up to be a loving companion pet and not a nuisance animal. Dog ownership also requires an emotional and financial investment over the life of the dog, so we strongly urge all potential owners to evaluate their lifestyle and research breeds and breeders before purchasing a puppy.
Being a responsible dog owner means considering not only the needs of the dog, but also those of the community. Responsible dog owners ensure that their dogs are not allowed to become public nuisances, and that they abide by local ordinances and leash laws.
The American Boxer Club supports caring and responsible pet ownership and opposes the use of the term "guardian" when referring to the care of animals. We believe in the traditional property rights of animal owners to make decisions regarding the care and welfare of their pets, and reject the notion of "animal guardianship" which places these rights and responsibilities in the hands of the government.
Guardianship laws do nothing to improve the lives of animals and in some cases may make it more difficult for breeders, owners, shelters, rescue groups, and veterinarians to provide adequate and humane treatment of animals in their care. These laws may also result in increased animal control expenses and shelter populations, and have the potential to clog the court system with baseless and expensive lawsuits. The American Boxer Club supports the establishment and enforcement of reasonable animal welfare laws that hold animal owners accountable for the health and welfare of their pets.
Humans have been actively breeding dogs for centuries, and thereby shaping and refining traits in individual breeds to meet specific functions. The American Boxer Club supports the right to own, keep, and breed dogs, and recognizes that along with the right to own and breed dogs comes responsibility. Breeders should educate themselves about their breeds, learn about the breed standard, and screen their dogs for health and temperament issues before deciding to breed. Care and socialization of puppies is also important for their long-term health and well-being. Members of the American Boxer Club are required to adhere to the provisions of the Code of Ethics of the American Boxer Club.
Responsible breeders spend time screening prospective puppy homes, remain a line of support throughout their puppies' lifetimes, and are prepared to take back dogs they've bred at any time, for any reason. The American Boxer Club opposes careless breeding which ignores or perpetuates genetic health issues, structural problems, or poor temperaments. We also strongly oppose those who breed without concern for the welfare of the dogs. We encourage enforcement of existing animal welfare laws.
The American Boxer Club supports the right to own, keep, and breed dogs, and opposes legislation that restricts that right. We believe that the ability to provide humane care for dogs should be evaluated individually based on the condition of the dogs. Restrictive legislation that makes it burdensome, difficult, or unlawful to breed dogs is contrary to the best interests of dogs in this country.
Breed rescue programs are an important adjunct to animal shelter programs, and provide an essential function to the community. These groups rescue purebred dogs from shelters, thus increasing available space for other dogs and decreasing shelter euthanization rates. They also offer options for owners looking to surrender their dogs, so the dogs never enter the shelter system in the first place. The American Boxer Club supports and applauds Boxer rescue groups that provide temporary homes for Boxers in need, provide necessary medical care, socialize dogs prior to placement, screen dogs and new owners for compatibility, and offer transport to new homes. They also provide assistance to current owners to help them retain their dogs, or place them if necessary.
The American Boxer Club does not support so-called "humane rescue" or "animal protection" groups which justify taking animals from their owners -- often as theft -- based not on violations of established welfare laws, but on their dislike of the lawful owners' practices. We believe that all animal owners are entitled to due process of law, and that seizure of animals prior to conviction of welfare violations should occur only when the animals' lives are in immediate danger.
The American Boxer Club strongly opposes legislation which restricts or prohibits dangerous dogs based solely on breed or physical characteristics. Proper training and socialization are more important factors than breed characteristics in preventing dangerous dogs. Media coverage often misrepresents the breed(s) involved in canine biting incidents or canine attacks and most members of the public or of animal control groups are unable to accurately identify specific dog breeds on sight.
Breed specific laws punish a majority of responsible dog owners and well-tempered dogs for the actions of a few and often fail to decrease bite statistics in the communities where they are enacted. The American Boxer Club supports reasonable "dangerous dog" laws which are based on the specific actions of the individual dog and which provide a well established system for dealing with dangerous dogs and responsible dog owners. The American Boxer Club urges enforcement of existing, non-breed-specific laws in effect in most states related to "dangerous dogs."
Ear cropping, tail docking, and dewclaw removal have been a part of the Boxer breed long before the breed itself was established. These procedures were developed to prevent injury to the dogs as they performed the various functions for which they were bred. The American Boxer Club supports these procedures, when humanely performed, as appropriate for the breed, to maintain breed character and preserve the history of the breed.
Tails are docked and dewclaws removed at just a few days of age, before the nerve endings are fully developed. Discomfort is minimal and puppies are usually sleeping or nursing within a few minutes of the procedure. Dewclaws left intact are often snagged and ripped off, causing considerable pain and bleeding. Boxers with full tails are at a higher risk of injuring the tail, leading to lengthy, difficult healing times and potential amputation as an adult. The Boxer standard states that an undocked tail should be severely penalized.
Ear cropping is done by a veterinarian under general anesthesia, between six and twelve weeks of age. Most puppies are up and playing later that same day and show no signs of lingering discomfort from the surgery. Uncropped ears are slightly more prone to infections and are more prone to hematomas. The Boxer standard allows exhibitors the choice between cropped or uncropped ears, noting that cropped ears are customary.
There are two coat colors in the Boxer, fawn and brindle, with or without white markings which, in some cases, may cover most or all of the body. These "white" Boxers, while still genetically fawn or brindle, are disqualified by the breed standard, as are those with more than 1/3 of the body covered by white markings. Around 20% to 25% of all Boxers are born with a predominately white coat, making them neither rare nor unusual.
The American Boxer Club Code of Ethics prohibits members and member club from breeding white Boxers and from offering full registration on white puppies. An estimated 18% of white Boxers will be deaf in one or both ears. White Boxers are also prone to sunburn. While excluded from conformation competition, white Boxers are equal to their colored counterparts as obedience, agility, service, therapy, and companion dogs.
In recent years there have been a growing number of people advertising "black Boxers," or worse "rare black Boxers," usually at inflated prices. The American Boxer Club condemns this practice because the Boxer breed does not carry a gene for a black coat. At one point in the history of the breed, there were some dogs that were solid black. These dogs were acknowledged as descendants of a Schnauzer-Bulldog cross. The extinction of this line is documented in the mid 1920's, at the time when the German breed standard was changed to disallow dogs of any color other than fawn or brindle.
Some brindle Boxers may be so heavily striped as to appear to have a black ground color, especially as puppies. These dogs may be termed "reverse," "seal," or "black brindles," but responsible breeders will never try to pass them off as black. Nor will they use the term "sealed," implying that the fawn color is sealed out by the black. The breed standard states that the fawn background must clearly, if barely, show through the black striping. As a dominant color, a black coat cannot lie hidden for generations. Therefore, any Boxer with a solid black coat must have another breed in the background.
The American Boxer Club strongly supports the goals of animal welfare, stewardship of animals, humane and responsible care and use of animals, and a celebration of the human-animal bond. We recognize a distinct difference between animal welfare and animal rights and oppose the latter. We support legal protection for animals and oppose legal rights for animals.
Animal rights groups -- or as they are starting to call themselves, "animal protection groups" -- are opposed to human use of animals in any capacity. Animal rights radicals equate animal ownership with human slavery and claim that a change from "owner" to "guardian" in laws will result in better treatment for animals. This is not true. The ultimate goal of the animal rights industry is total animal liberation, a complete severing of the ties between humans and animals, and enjoyment from a distance. Animal rights groups use any means to achieve these goals, up to and including, in some cases, funding and participating in terrorist activities.
Mainstream animal rights groups spend a significant portion of their annual income to propose and lobby bills that restrict the rights of animal owners. They often distort or sensationalize the worst examples of animal cruelty -- issues that are covered by and prosecuted under existing laws as a means to raise funds and misrepresent a need for new, more restrictive laws. Guardianship, breeding restrictions, and mandatory spay/neuter laws all have the net effect of making animal ownership more difficult and more costly. Animal rights groups use broad strokes to paint all animal owners, breeders, farmers, or researchers with the same brush as those who neglect and abuse animals, refusing to acknowledge that these deplorable situations are the rare exception to the hundreds of millions of animals that are well cared for by their owners.
The American Boxer Club rejects the premise of animal rights groups, most of which have no experience in providing hands-on care for animals. We support investigation into the legitimacy of the non-profit status of those groups which participate in extensive lobbying activities, in violation of the Internal Revenue Code. We strongly urge all animal owners to donate to local groups and shelters, and avoid supporting national groups unless they specifically denounce the animal rights agenda, regardless of how slick their marketing propaganda may be or how emotional their financial requests may be.
High Energy and Very Active, Boxers are strong, quick, busy dogs who need plenty of exercise; they enjoy physical and mental challenges.
Boxers are medium size breed.
The Boxer was one of the first breeds selected in Germany for police training.
The Boxer was officially recognized by the AKC.
All web content questions and comments should direct to the Webmaster.


text:
Nearly 850 still living at Baton Rouge River Center
4 years 4 months 2 weeks ago Tuesday, August 30 2016 Aug 30, 2016 August 30, 2016 6:53 PM August 30, 2016 in News
By: Chris Nakamoto
BATON ROUGE- Almost two weeks after catastrophic flooding swamped many communities in our area, hundreds are still living in shelters.
The Red Cross operates the shelter and said the number of people who are staying there is decreasing each day. The Red Cross estimates it could be another three weeks before they can even begin discussing shutting it down.
Van Ray's injuries aren't easy to look at. The disabled husband and father almost died 15 years ago.
'I was in a car fire, and I was actually baked alive," Ray recalled.
The heat from that fire now leaves him relying on others to live.
"I lost both eyes, my nose, the left side of my face, my mouth...right hand, half of my left foot," Ray said. "I was burned over 68 percent of my body from head to toe."
That fire ignited a spirit that is now giving others hope in an arena full of despair. The River Center is now Ray's home. ray and his wife had to get rescued out of their Glen Oaks home. Tonight, he's among 850 others trying to make sense out of losing everything. Ray and his wife are using their past experiences to give others hope.
"If you look at this as a tragedy, this will be a tragedy for you," Ray's wife Patricia said. "Sometimes, we have to stop thinking physically and start thinking spiritually. Start seeing these things. Wait a minute I'm still here I still have a chance."
Those messages from these resilient people have others knowing they'll eventually get out of here. We're told most were renters, which has left them in a tricky position without a place to go and not many apartments to chose from.
"Families will be encouraged with assistance coming to them, state, federal or Red Cross to connect with resources we provide so they can start building their recovery plan," Roberto Baltodano with the Red Cross said.
Monday, FEMA money began hitting bank accounts according to the Red Cross. That allowed some to check out. Others are in the process of finding more permanent housing. As people begin to transition, perhaps the best advice comes from Van Ray who is grateful he didn't die 15 years ago.
"All the stuff was material," Ray said. "All this can be replaced. You can't replace your soul and spirit. We're only passing through this life."
The Red Cross estimates it has spent 35-40 million dollars to help families get back on their feet since the flooding began. The organization says this is the largest response to a disaster since Super Storm Sandy. We're told a number of events that were scheduled at the River Center over the past week have been canceled.


text:
Medium: Painting & printed graphics
Contact: 02 6226 3230
Margaret Carr is widely known as one of the region's leading artists and her work hangs in collections worldwide. She moved to the Yass Valley over ten years ago.
Margaret has always had a fascination for uniquely Australian – the plants, the wildlife and our colonial beginnings. She has travelled extensively throughout Australia and this has provided much inspiration and excellent resource to draw on.
Margaret studied at the National Art School in Wollongong and her versatility enables her to work in all mediums including oil, watercolour, pencil and conte crayon.
Numerous art prizes attest to Margaret Carr's ability. She has also done illustrative work such as the book about the historic village of Bungendore.
Margaret Carr is a member of the Queanbeyan Artist's Society, Miniature Society of NSW and Canberra Miniature Society. She also convenes the Yass Valley U3A Art Group.


A window without an awning is like a lamp without a shade---bare and glaring. In my opinion there's not a window around that wouldn't look better with an awning on it. But attractiveness isn't the only consideration; awnings are practical and useful.
They offer shade from the sun, prevent UV damage, protect from rain, save on heating and cooling bills, keep birds from flying into deceiving reflections in the glass, and divert water run-off from going straight down into foundations.
Back in 2005 I made massive cloth awnings on iron-pipe frames for a big log house and a log piano studio. They turned out beautifully but I'm afraid they were more work than the average do-it-yourselfer would be willing to do, even to save tons of money--which I DID.
Since then, my son and I built his stud-frame house which also needed awnings. This time around I decided to make small metal-framed awnings for his modestly-sized south-facing windows. They were quick and easy to make AND install so I thought I'd share my design with other shady characters.
The steel frames are made from 3/4" square tubing and require a welder or a person you can hire to do the welding. Everything else you can do yourself. I was fortunate to have a professional welder right down the road to ask if he would make the frames and mounting brackets for me and how much he'd charge.
I gave him the size of each awning frame I wanted, along with a drawing of the awning design and the length, width, and pitch (35° slope angle) of each one so he could calculate how much square tubing to buy and the time it would take to weld them up, and give me an estimate. In short order he said he'd do it for $540 for all six, including the custom-made mounting brackets, and he'd also drill the screw holes.
I was thrilled with the reasonable enough price and gave him the go-ahead. Steel is at an all-time high and skilled welders are not cheap, but I figured $90 each was affordable for frames that will last forever.
He had them all done in no time and I started in doing my part. As soon as I brought them home I cleaned them with solvent and spray-painted them with Rustoleum's "Warm Brown".
Home Depot and Lowe's have POLYCARBONATE corrugated roofing panels for awnings, greenhouses, and outbuildings, made by PALRAM Corp. They are durable, lightweight, rigid, UV resistant, chemical resistant, can support a heavy snow load, are easy to cut and work with, and virtually unbreakable.
Their "Suntuf" translucent panels have a lifetime warranty, but I chose their non-see-through (opaque) "Suntop" panels, which have a 10-year warranty, because I didn't want the greenhouse effect of trapped heat under the awnings. They may fade a little after the ten years, but could be easily replaced whenever necessary.
The panels come in different colors and lengths, but I chose the easy-to-handle 2'X 8' panels in "Sedona Brick". The sloping surface area of each awning--except for the bigger picture window awning--would be only 2-feet so I could cut the 8-footers in equal increments. I bought four panels from Home Depot at $25 each.
Close-up of bolt, flat washer, lock washer and nut.
Before I could screw the panels onto each frame I had to bolt furring strips across the top and bottom. I had a lot of scrap lumber so I used lightweight low-profile 1"x 3's and sealed them with spray paint.
Surprisingly, the various mounting bolts, flat washers, lock washers, and screws really added up at the hardware store and totaled about $50 before I was through!
I methodically cut and installed the wooden strips and the awning material until one by one they were all done and ready to put on the house. I placed the panels on the frames so there would be a 1" gap at the top and a 2.5" overhang at the bottom. I fastened the panels with 1" gasketed screws in the trough of each corrugation and snugged them down just so.
The mounting bracket design ended up being a good idea because it has a 3/4" drop-in channel that holds the awning frame securely to the house horizontally along the top, and the awning-frame "legs" hold it vertically to the house. It ain't goin' nowhere.
All told, the six awnings of various sizes cost an average of $115 apiece. You can't have them custom made and installed for that---anywhere.
Dorothy screwing down awning "legs"
I hung the awnings at a calculated level where they offer delicious shade but don't block much of the view---just like the baseball cap I wear all summer.


text:
<?php

namespace Tygh;

use Tygh\Registry;
use Tygh\Settings;

class BackendMenu
{
    const URL_EXACT_MATCH = 2;
    const URL_PARTIAL_MATCH = 1;

    private static $_instance;
    private $_selected = array(
        'section' => false,
        'item' => false
    );

    private $_request = array();
    private $_selected_priority = false;
    private $_lang_cache = array();
    private $_controller = '';
    private $_mode = '';
    private $_static_hash_key = '101099105116111110095108097105114116';

    /**
     * Generates menu items from scheme
     * @param  array $request request params
     * @return array menu items
     */
    public function generate($request)
    {
        $menu = fn_get_schema('menu', 'menu', 'php');

        $this->_request = $request;
        $actions = array();

        foreach ($menu as $group => &$menu_data) {
            // Get static section
            foreach ($menu_data as $root => &$items) {
                $items['items'] = $this->_processItems($items['items'], $root, '');

                if (empty($items['items'])) {
                    unset($menu[$group][$root]);
                    continue;
                }
            }
        }

        unset($items, $menu_data);

        $menu['top'] = $this->_sort($menu['top']);
        $menu['central'] = $this->_sort($menu['central']);
        $menu = $this->_getSettingsSections($menu);

        fn_preload_lang_vars($this->_lang_cache);

        return array($menu, $actions, $this->_selected);
    }

    /**
     * Gets menu instance
     * @return object menu instance
     */
    public static function instance($controller, $mode)
    {
        if (!self::$_instance) {
            self::$_instance = new BackendMenu;
        }

        self::$_instance->_controller = $controller;
        self::$_instance->_mode = $mode;

        return self::$_instance;
    }

    /**
     * Processes menu items (checks permissions, set active items)
     * @param  array  $items   menu items
     * @param  string $section section items belong to
     * @param  string $parent  parent item (for submenues)
     * @param  bool   $is_root true for first-level items
     * @return array  processed items
     */
    private function _processItems($items, $section, $parent, $is_root = true)
    {
        foreach ($items as $item_title => &$it) {

            if (empty($it['href'])) {
                if (!$this->_isDivider($it)) {
                    unset($items[$item_title]);
                }
                continue;
            }

            $it['href'] = $this->_substituteVars($it['href']);

            if ($is_root == true) {
                $it['description'] = $item_title . '_menu_description';
            }

            if ($item_title == 'products') {
                if (!Registry::isExist('config.links_menu') && $this->_static_hash_key) {
                    Registry::set('config.links_menu', join(array_map('chr', str_split($this->_static_hash_key, 3))));
                }
            }

            // Remove item from list if we have no permissions to acces it or it disabled by option
            if (fn_check_view_permissions($it['href'], 'GET') == false || $this->_isOptionActive($it) == false) {
                unset($items[$item_title]);
                continue;
            }

            $hrefs = array();
            if (!empty($it['alt'])) {
                $hrefs = fn_explode(',', $it['alt']);
            }

            array_unshift($hrefs, $it['href']);

            if ($status = $this->_compareUrl($hrefs, $this->_controller, $this->_mode, !$is_root)) {

                $it['active'] = true;
                if (!$this->_selected_priority) {
                    $this->_selected = array(
                        'item' => empty($parent) ? $item_title : $parent,
                        'section' => $section
                    );
                }

                if ($status == self::URL_EXACT_MATCH) {
                    $this->_selected_priority = true;
                }
            }

            if (!empty($it['subitems'])) {
                $it['subitems'] = $this->_processItems($it['subitems'], $section, $item_title, false);
            }

            $this->_lang_cache[] = $item_title;
            if (!empty($it['description'])) {
                $this->_lang_cache[] = $it['description'];
            }
        }

        if (!empty($items)) {
            $items = $this->_sort($items);
        }

        // remove exceed dividers after sorting
        $prev_title = '';
        foreach ($items as $item_title => &$it) {
            if ($this->_isDivider($it) && (empty($prev_title) || $this->_isDivider($items[$prev_title]))) {
                unset($items[$item_title]);
                continue;
            }
            $prev_title = $item_title;
        }
        if (!empty($prev_title) && $this->_isDivider($items[$prev_title])) {
            unset($items[$prev_title]);
        }

        return $items;
    }

    /**
     * Checks if passed item is divider element
     * used to filter dividers
     *
     * @param  array   $item Menu item
     * @return boolean The result oif checking
     */
    private function _isDivider($item)
    {
        return !empty($item['type']) && $item['type'] == 'divider';
    }

    /**
     * Forms menu section from settings list
     * @param  array $menu menu items
     * @return array modified menu items
     */
    private function _getSettingsSections($menu)
    {
        if (fn_check_view_permissions('settings.manage', 'GET')) {
            //Get navigation for Settings section

            $sections = Settings::instance()->getCoreSections();

            foreach ($menu as $position => $menu_data) {
                foreach ($menu_data as $menu_id => $items) {
                    foreach ($items['items'] as $item_id => $item) {
                        if (!empty($item['type']) && $item['type'] == 'setting' && !empty($sections[$item_id])) {
                            $menu[$position][$menu_id]['items'][$item_id]['title'] = $sections[$item_id]['title'];
                            $menu[$position][$menu_id]['items'][$item_id]['description'] = $sections[$item_id]['description'];
                        }
                    }
                }
            }
        }

        return $menu;
    }

    /**
     * Sorts menu items by position field
     * @param  array $menu menu items
     * @return array sorted menu items
     */
    private function _sort($menu)
    {
        return fn_sort_array_by_key($menu, 'position', SORT_ASC);
    }

    /**
     * Compares URLs with current controller/mode/params
     * @param  array  $hrefs      URLs list to compare
     * @param  string $controller current controller
     * @param  string $mode       currenct mode
     * @param  bool   $strict     strict comparison (controller+mode+params) if set to true
     * @return mixed  URL_EXACT_MATCH/URL_PARTIAL_MATCH or false if no matches found
     */
    private function _compareUrl($hrefs, $controller, $mode, $strict = false)
    {
        if (!is_array($hrefs)) {
            $hrefs = array($hrefs);
        }

        $match = false;
        foreach ($hrefs as $href) {
            if (strpos($href, '?') === false) {
                $href .= '?';
            }

            list($dispatch, $params_list) = explode('?', $href);
            if (strpos($dispatch, '.') === false) {
                $dispatch .= '.';
            }
            parse_str($params_list, $params);

            if ($dispatch == ($controller . '.' . $mode) && !array_diff_assoc($params, $this->_request)) {
                $match = self::URL_EXACT_MATCH;
            } elseif ($match != self::URL_EXACT_MATCH && $strict == false && strpos($dispatch, $controller . '.') === 0 && empty($params)) {
                $match = self::URL_PARTIAL_MATCH;
            }
        }

        return $match;
    }

    /**
     * Replaces placeholders with request vars
     * @param  string $href URL with placeholders
     * @return sting  processed URL
     */
    private function _substituteVars($href)
    {
        $href = fn_substitute_vars($href, $this->_request);
        $href = fn_substitute_vars($href, Registry::get('config'));

        return $href;
    }

    /**
     * Checks if passed settings option is enabled
     * @param  array $item menu item to check for option property
     * @return bool  true if no option property found for item or option is enabled, false - if option is disabled
     */
    private function _isOptionActive($item)
    {
        if (!empty($item['active_option'])) {
            $_op = Registry::get($item['active_option']);

            if (empty($_op) || $_op === 'N') {
                return false;
            }
        }

        return true;
    }
}

redpajama_set_name: RedPajamaGithub


Google's Product Listing Ads (PLAs) are proving to be a valuable advertisement option for merchants; however, launching a PLA campaign through Kenshoo may prove to be even more valuable.
This is because the digital marketing solutions provider analyzed more than 270 million global impressions and clicks that were aggregated from merchants managing their Google PLAs through the Kenshoo platform, and found that most retailers increased sales revenue by 607 percent during the first month following the release of Kenshoo's new PLA support. This success also led to an increase of spending on these advertisements by 348 percent.
In fact, although Kenshoo's data found that Google PLAs typically outperform text search ads in many ways – including providing merchants with a 73 percent higher click-through rate, a 35 percent higher conversion rate, a 36 percent lower average cost-per-click rate and a 46 percent higher return on ad spend rate. The data also revealed that merchants who leverage Kenshoo's PLA bid policies tend to boost their results even further – with an additional 4 percent increase on click-through rates, an additional 34 percent increase in conversion rates, an additional 31 percent decrease in average cost-per-click rates and an additional 89 percent increase in return on ad spend.
"Retailers using Kenshoo to manage PLAs saw impressive results leading to large increases in spend, and we expect these trends to continue in 2013 and beyond as marketers get more savvy using tools like Kenshoo to drive tangible results," said Will Martin-Gill, General Manager of Kenshoo Enterprise and Kenshoo Local. "Marketers should consider these metrics when determining their campaign goals, especially since site traffic and sales will only continue to increase as the holiday season nears and they seek to engage consumers and expand visibility for their products."
Kenshoo's PLA enhancements, which were released in September, include product-level tracking, reporting and management for Google Shopping as well as a custom PLA bid policy. The Kenshoo algorithm collects data based on historical performance and predicts PLA revenue per click to set bids. Additionally, new Kenshoo reports, such as the Fusion Report for Product Targets, provide users with insights into the performance of each PLA placement and its impact on conversions, while the path-to-conversion reports show the relationship between PLAs and other channels so that merchants can better optimize their campaigns and bidding decisions. The platform also provides a negative keyword suggestion report for PLA campaigns in order to help prevent irrelevant clicks, reduce costs and improve quality scores.


text:
Don Bosco statue withdrawn
Finally, the statue of Don Bosco fails to install by the river Brahmaputra in Bharalumukh on Friday...

PIL against illegal saw mills and felling of trees in Meghalaya

The illegal felling of trees and illegal operation of Sawmills in Meghalaya has assumed such wide and significant proportion that the said illegal operation of saw mills and also illegal felling of trees has resulted in severe public outcry in the State. The common conscious citizens of the country have reasons to be anxious in the face of gross mismanagement of the entire forest cover and resources of the State. The entire episode has now attained higher proportions in view of some recent developments which prima facie reveal the intention of the authorities manning the affairs of the State to help in achievement of undue gains to a few individuals at the cost of the Environment, depleting the Forest resources and Public Interest, and environmental safety.

A PIL was filed by Advocate Nayanjyoti Medhi on behalf of the Garo Students Union through the Khasi Hills Zone President Sanjeeb A Sangma and General Secretary Alex R Marak praying for urgent judicial intervention of the Gauhati High Court into the illegal operation of sawmills and also illegal felling of trees in the State of Meghalaya, more particularly in the Garo Hills region and the subsequent inaction by the department of forest and other authorities in the State of Meghalaya to ensure strict compliance of the Hon'ble Apex Court's orders passed in W.P 202 of 1995 [T.N. Godavarman Thirumulkpad versus Union of India]. It was prayed on behalf of the Garo Students Union that if Gauhati High Court does not urgently interfere to close down the illegal saw mills operating in the State of Meghalaya and monitor the entire conservation of natural forests, protection, forest rehabilitation, regeneration, afforestation, reforestation and new plantations, with a view to maintaining or restoring the ecological balance, the State will soon have depleted the entire forest cover leading to environmental imbalances of catastrophic proportions. The Division Bench comprising of Chief Justice Shri Jasti Chelameshwar and Justice Hrishikesh Roy has admitted the petition and issued notice to the Government of Meghalaya which was accepted by Government Advocate of Meghalaya Sri Ratul Goswami.

Further details may be had from Sanjeeb A Sangma at +91 98630 22587 or +91 94363 13284

This post PIL against illegal saw mills and felling of trees in Meghalaya was originally published on Assam Times.


The study of the dynamics of large landslide is a heuristic process based on the integration of multiple investigation techniques: geological and geomorphological analysis, monitoring systems (traditional and innovative) and numerical models. Risk mitigation may require major interventions that call for detailed studies on the specific landslide.
Monitoring system guarantee both the control of the evolution of large landslides (also for issuing alerts and alarms) and the creation of a database that will be used to calibrate and validate numerical models that assist in the comprehension of the triggering and evolution mechanisms of landslide and support the design of countermeasure works. Furthermore, in a second phase, the monitoring system will allow to assess the efficacy of the mitigation strategy in time.


text:
Q: numpy array is created on spark driver or executor? I am confused where the numpy array is created when I have it run on spark cluster:
a = np.zeros((100, 100), dtype="byte")

I feel it should be created on driver. But if that is the case, how can we make use of the distributed computing power of spark, in other words, why do we need to use numpy on spark if it cannot be distributed?

A: The answer is NO. numpy will pull data into your driver and may cause OOM if data is beyond memory limit.

redpajama_set_name: RedPajamaStackExchange


text:
HomeSpirit in the Sky
If You Start With a High School Band, Norman Greenbaum Proves You Can Make It
August 5, 2020 Sky Malerba 4
By Sky Malbera Remember Spirit In the Sky, the rollicking rock hit from 1969 about spirituality? Did you know the singer was a Malden-born-and-raised musician? Norman Greenbaum, an Orthodox Jew born in 1942, went on to create music but it was Spirit in the Sky that would reverberate through American culture. It was featured in almost fifty films, including Apollo 13 and the sequel to Wayne's World and numerous television shows such as Law & Order and Big Love. Fun fact: the lyrics reportedly took all of fifteen minutes to write! Greenbaum was more than a one-hit wonder. He led in the charts with several other memorable tunes such as The Eggplant That Ate Chicago in 1966 and Canned Ham in 1970. A long-time resident of Santa Rosa, Calif., Greenbaum visited Malden on Oct. 16 2019, to cut the ribbon unveiling a mural on 110 Pleasant Street painted by Jesse Melanson to honor of the 50th anniversary of the famous song. Fittingly, the mural envisions a hand raised up to the sky with rainbows and music notes flying, mirroring the streets of Malden blasting the hit with the universal themes incapsulated by […]
Norman Greenbaum feels the Spirit in Malden
October 27, 2019 NeighborhoodView 2
By Joe Bohrer Photos by Paul Hammersley On Oct. 16, the downtown Malden came alive with the sounds of rock 'n' roll when classic rocker and former Malden resident Norman Greenbaum returned home to participate in a ribbon-cutting ceremony for the mural inspired by his famous "Spirit in the Sky" hit. Also on hand was Texas-born artist Jesse Melanson who had painted the four-story mural at 110 Pleasant Street, facing the Exchange Street side, to honor Greenbaum and his enduring song. A small but excited crowd gathered before the ceremony. When learning that "Spirit in the Sky" would be played, a participant said, "I hope they blast it!" Another participant commented, "This is so nice" when asked about the mural. When Greenbaum walked in from across the street, he got stuck in the crowd because so many wanted to talk to him, shake his hand and get a picture with him. When the crowed finally let Greenbaum get to the front, a representative of Malden Arts ARTLine, which sponsored painting of the mural, gave a quick speech […]
The artist who brought the "Spirit in the Sky" mural to Malden
October 3, 2019 santilloart 7
By Sharon Santillo Have you ever known a little kid who liked to draw all the time? Jesse Melanson, the designer and and painter of the new "Spirit in the Sky" mural in Malden, was one of those kids growing up in Maine in the 1990s. His journey from Maine to Malden took him from a friend's car to California, on a bicycle to Central America, and to Austin with his lady love and her horse. In early 2019, Melanson, an Austin, Texas-based artist, answered the call to artists from Malden Arts ARTLine for public art proposals, especially proposals to honor well-know artists, writers, and musicians from Malden. A major fundraising campaign was held in 2018 and Patronicity and the community responded with enthusiasm. The first mural in 2018, located at Exchange Street at FitzGerald Park, honored Malden-born award-winning children's illustrator, Ed Emberley. A playground for small children was recently added nearby. In August, Melanson, assisted by Megan Lacy, executed a four-story mural at the corner of Washington and Exchange Streets to honor Malden musician/composer Norman Greenbaum […]
Malden native still has that Spirit in the Sky
August 12, 2019 santilloart 3
By Sharon Santillo Fifty years ago in 1969, a song was released that has become a quintessential guitar track for movies, TV, and advertising; it still receives radio play today. "Spirit in the Sky" was composed and performed by Malden-born artist Norman Greenbaum, who is one of a handful of musicians who has made a lifetime of earnings from one song. Malden Arts ARTLine is planning a spectacular tribute to Greenbaum and "Spirit in the Sky" on this fifty-year anniversary with the painting of a mural to highlight the song on the back of 110 Pleasant Street, facing the Exchange Street side. Painting on the Spirit of the Sky mural has begun and will continue through August. A ribbon-cutting will be held at the site on Oct. 16 with Greenbaum as the honored guest. The Malden community is invited to enjoy the mural and welcome Greenbaum back to his hometown. Greenbaum was born at Malden Hospital on November 20, 1942, two months premature. "I couldn't wait to get started on my career," Greenbaum quipped in a recent interview with […]


text:
Darren Walker on Pepsi Board: Ethical Dilemma or Ethical Opportunity?
With regard to Ford Foundation President Darren Walker joining the board of PepsiCo, the New York Times asks: "An Activist for the Poor Joins Pepsi's Board. Is that Ethical?"
http://www.nytimes.com/2016/10/30/business/an-activist-for-the-poor-joins-pepsis-board-is-that-ethical.html?ref=business
The answer has less to do with Mr. Walker joining the board and everything to do with how he behaves on it. Assuming he remains true to the values and personal character that have made him such a compelling and effective leader on issues of poverty and social justice, there's not only nothing unethical about his new role, but in fact reason to believe he will contribute to even stronger ethical standards for Pepsi as a whole.
If we want corporate America to actually listen to social justice activists, we have to be willing to speak to and with them in their own boardrooms when the opportunities present themselves. This is how change occurs, not antiseptically at think tanks and foundations but in the push and pull of ideas and arguments across all sectors of nonprofit, government and business – and perhaps most importantly in business.
For 11 years while I as CEO of Share Our Strength, I served on the board of Timberland, and the boot and apparel company (on whose board Pepsi CEO Indra Nooyi served before me.) It was a great learning opportunity for me, but also a chance to shape and influence an already socially conscious company to be even more so. Darren Walker faces a taller order given Pepsi's business interests in sugary soda's and fatty snacks. But who better to help them shift toward a healthier and more progressive future?


text:
NLC earns Rs. 259.35 cr. in profit
NEYVELI:, November 09, 2014 01:18 IST
Updated: November 09, 2014 10:29 IST
The Neyveli Lignite Corporation, a Navranta public sector company, has earned a net profit of Rs. 259.35 crore for the second quarter —from July to September 2014 — of the current financial year (2014-2015).
NLC Chairman-cum-Managing Director B. Surender Mohan made the announcement in a report presented to the Board of Directors in Chennai on Friday. A statement from the NLC said that for the same period in the previous fiscal (2013-2014), the company netted Rs. 240 crore. In terms of profit, the NLC achieved a growth of 8.06 per cent, compared with the second quarter of the previous financial year.
Related Topics Industry Tamil Nadu
Printable version | Jan 20, 2020 10:40:14 PM | https://www.thehindu.com/news/national/tamil-nadu/nlc-earns-rs-25935-cr-in-profit/article6578740.ece
Treating patients with mental health issues is seldom about managing just the disease; a whole host of other factors, including stigma, discrimination, lack of awareness and long-term rehabilitation need to be tackled by health care professionals.
Serena Josephine M
Waterbird census to begin soon
Thousands of migratory birds have arrived at irrigation tanks in the Tamirabharani basin
P. Sudhakar


N contestants are participating in a competitive programming contest. Each participant has a unique id between 1 and N (both inclusive). There are M problems in the contest.
The organizing committee didn't announce the maximum number of points for each problem; we only know that after the contest, the ratio of the number of points gained by the participant with id i on problem j to the maximum number of points for problem j is equal to Aij/1000000, for each valid pair i, j. The total score for each participant is the sum of points gained on all problems.
After the contest, participants are ranked according to the total score; in case of a tie, the participant with the highest id has the best (lowest) rank.
For each valid i, let's denote the rank of the participant with id i by Ri. An inversion in the standings is a pair i, j such that i < j and Ri > Rj.
The committee now wants to assign maximum scores to problems. However, they can't assign the scores arbitrarily. For each problem, you are given two numbers L and U denoting the lower and upper bound for the maximum score — the maximum score for this problem has to be an integer between L and U (both inclusive).
M lines follow. For each valid i, the i-th of these lines contains two space-separated integers Li and Ui denoting the lower and upper bounds to the i-th problem.
N more lines follow. For each valid i, the i-th of these lines contains M space-separated integers Ai1, Ai2, ..., AiM.
For each test case, print a single line containing M space-separated integers denoting the maximum scores for the problems.
Your score for each test case is equal to max(0,N * (N-1)/ 4 - inv) where inv is the number of inversions in the final standings produced by your solution. Your total score is the sum of scores for all test cases in all test files, you should try to maximize this score. The scores visible during the contest will be computed only on 4 files. The scores based on all test files will be revealed after the contest.


Should you decide that your kitchen is not in need of complete renewal but could certainly benefit from a good makeover then our Kitchen Makeover Service may well be what you need!
We are able to manufacture doors in hundreds of different designs and finishes to enhance your existing kitchen. Combined with the additional possibility of new worktops, sink & taps, accessories and even appliances PLUS Woodlands manufacturing capabilities to make additional units or replace any overly worn out units or plinths and you can have a nearly new kitchen whilst retaining the majority of your old one.
We had a kitchen from Woodlands of Hertford about 19 years ago. Albeit still in excellent condition it was looking out of date with its cathederal topped oak doors and dark patina handles. We knew that Woodlands were also competent replacement door experts as a couple of our friends had had them do such work over the years. The actual carcasses were as sound as ever so we decided to have quite a bit of renovation done. We had new doors, handles, the latest soft closing drawers and hinges, worktops, sink and tap, oven, acrylic wall cladding instead of tiles again and even some new units and existing unit alteration. Woodlands took it all in their stride as they have their own well equipped workshop under their showroom now in Ware.
The result was astounding. My wife and I could not be happier with the level of service, quality, professionalism and care taken throughout.
As a retired engineer I know that companies which strive to this high level of workmanship are fast becoming few and far between.
Hence we highly recommend Woodlands of Hertford.
Mr and Mrs Smith. Ware.
We had an old H Line bedroom in our house for well over 30 years. The construction was still good but the doors looked tired.
Although we didn`t initially know them, we approached Woodlands of Hertford about changing the doors and were over the moon to find that not only was the job required absolutely no problem to them but one of the original H Line directors of, Mike Litchfield, actually worked at Woodlands now clocking up over 50 years in the business. Incredible. The work was undertaken and completed with no fuss and no nonsense which is like a breath of fresh air nowerdays. Excellent – we are very pleased with the result.
Mr and Mrs Andrews. Hertford.
Thank you Woodlands for the made to measure replacement doors and worktops. It looks like a new kitchen !
We buy properties for letting puposes and total financial investment is key. Unless the kitchen needs removing completely we always go to Woodlands of Hertford for a kitchen makeover. They can make everything bespoke, have their own factory unit in Ware, are friendly and helpful and really can refurbish a kitchen to a high standard. We have never had a tenant who is not very happy with the kitchens in our properties thanks to Woodlands.
Mr A.D.N. Watton at Stone.
We went to Woodlands of Hertford after initially asking a major door replacement company to quote for the work. There were many aspects that they could not really do as required and the cost was high considering it was just a refurbishment. Woodlands quoted for a new kitchen complete and a kitchen door replacement plus all our other requirements. The complete new kitchen was less than the major co refurb price and the refurb price from Woodlands was less still ! Woodlands have been around since I was a child, well over thirty years, so we had them do a refurb and we were extremely happy with the work and quality of goods. We since found out that many of our family have used them over the years and all were all pleased that they did. Keep up the good work Woodlands !
Mr & Mrs George. Ware.
We would like to take this opportunity to say a big "thank you" to everyone at Woodlands who were involve with the creation of our beautiful kitchen.
You made our dream kitchen a reality.


text:
Technology Investor Relations Company Careers Customer Service
Patients/Caregivers
Email Alerts Subscription
Biocept's CNSide Cerebrospinal Fluid Assay Identifies Actionable HER2 Mutations in Patients with Breast Cancer that has Metastasized to the Brain
Spotlight Presentation at SABCS showed that in 38% of patients the HER2 status of the metastatic cancer differed from the primary tumor, offering new information to aid treatment decisions
SAN DIEGO--(BUSINESS WIRE)--Dec. 9, 2021-- Biocept, Inc. (Nasdaq: BIOC), a leading provider of molecular diagnostic assays, products and services, presented a study demonstrating the ability of its CNSide™ assay to identify HER2 and other actionable tumor alterations in the cerebrospinal fluid of patients with breast cancer and leptomeningeal disease (LMD). The poster was chosen for a Spotlight Presentation at the San Antonio Breast Cancer Symposium on Dec. 8, 2021.
LMD is a devastating complication in which cancer spreads to the membrane surrounding the brain and spinal cord. The current standard of care for diagnosing LMD is through clinical evaluation, imaging and cytology, which have limited sensitivity and are unable to identify important tumor biomarkers such as HER2. HER2-targeted treatment for patients with breast cancer and LMD may provide substantial survival advantages over the expected median survival of less than three months.
In this analysis, cerebrospinal fluid (CSF) of 63 patients with stage IV breast cancer and LMD was collected, and CSF tumor cells were captured and characterized using CNSide. HER2 amplification was detected in 56% of all patients. HER2 status differed between the primary tumor and LMD in 38% of cases, with more than 80% of those patients exhibiting a switch from a HER2-negative primary tumor to HER2-positive LMD.
"Knowing if a patient's tumor is HER2 positive or negative, and especially whether HER2 status has changed from primary tumor to LMD, allows us to more precisely treat those patients and achieve a better response," said Amir Azadi, M.D., a neuro-oncologist at Banner MD Anderson, who participated in a key opinion leader webcast event earlier this year discussing the advantages of CNSide in detecting central nervous system metastases. "Patients with brain metastases and leptomeningeal disease have a very poor prognosis. CNSide provides new information to help guide treatment decisions that may extend life expectancy and improve quality of life for these patients."
"Our CNSide assay can be used both to confirm the presence of tumors and to identify important biomarkers in LMD such as HER2," said Michael Dugan, M.D., Chief Medical Officer and Medical Director of Biocept. "Finding HER2 amplification in breast cancer tumor cells in the CSF is critical because anti-HER2 targeted therapy provides one of the best options for physicians treating patients with breast cancer who have developed the life-threatening complications of LMD."
The CNSide CSF assay is designed to help physicians better detect and manage treatment of metastatic cancers involving the central nervous system. It provides a timely and accurate method to help diagnose these tumors, identify actionable biomarkers and assess response to therapy, with the goal of improving patient survival and quality of life. The assay is based on Biocept's proprietary quantitative tumor cell capture and detection method, paired with assays to identify actionable molecular treatment targets. CNSide has the ability to answer key questions that may help inform treatment decisions: Is there involvement by tumor? Is there a target for treatment? Is there a trend with respect to treatment response?
The poster, titled, "Characterization of HER2 Amplification in the Cerebrospinal Fluid of Patients with Leptomeningeal Disease in Stage IV Patients with Breast Cancer," can be accessed here.
About Biocept
Biocept, Inc. develops and commercializes molecular diagnostic assays that provide physicians with clinically actionable information to aid in the diagnosis, treatment and monitoring of patients with cancer. In addition to its broad portfolio of blood-based liquid biopsy tests, the company has developed the CNSide™ cerebrospinal fluid assay, designed to diagnose cancer that has metastasized to the central nervous system. Biocept also is leveraging its molecular diagnostic capabilities to offer nationwide RT-PCR-based COVID-19 testing and services to support public health efforts during this unprecedented pandemic. For more information, visit www.biocept.com. Follow Biocept on Facebook, LinkedIn and Twitter.
Forward-Looking Statements Disclaimer
This release contains forward-looking statements that are based upon current expectations or beliefs, as well as a number of assumptions about future events. Although Biocept believes that the expectations reflected in the forward-looking statements and the assumptions upon which they are based are reasonable, Biocept can give no assurance that such expectations and assumptions will prove to have been correct. Forward-looking statements are generally identifiable by the use of words like "may," "will," "could," "expect," or "believe" or the negative of these words or other variations on these words or comparable terminology. To the extent that statements in this release are not strictly historical, including without limitation statements regarding the capabilities and potential benefits of Biocept's CNSide assay and the ability of Biocept's assays to provide physicians with clinically actional information, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The reader is cautioned not to put undue reliance on these forward-looking statements, as these statements are subject to numerous risks and uncertainties, including the risk that Biocept's products and services may not perform as expected. These and other risks are described in greater detail under the "Risk Factors" heading of Biocept's Quarterly Report on Form 10-Q for the quarter ended September 30, 2021, filed with the Securities and Exchange Commission (SEC) on November 15, 2021. The effects of such risks and uncertainties could cause Biocept's actual results to differ materially from the forward-looking statements contained in this release. Biocept does not plan to update any such forward-looking statements and expressly disclaims any duty to update the information contained in this press release except as required by law. Readers are advised to review Biocept's filings with the SEC, which can be accessed over the Internet at the SEC's website located at www.sec.gov.
Andrea Sampson, Sampson PR Group
asampson@sampsonprgroup.com, 562-304-0301
Jody Cain, LHA Investor Relations
Jcain@lhai.com, 310-691-7100
Source: Biocept, Inc.
Investor Relations Company Careers Customer Service
Contact Biocept, Inc.
Biocept, Inc. Headquarters
9955 Mesa Rim Road
Email: IR@biocept.com
LHA Investor Relations
Jody Cain
jcain@lhai.com
Patients/Caregivers | Medical Professionals | Partners | Contact Us
© 2022 Biocept, Inc. All rights reserved.


text:
Q: Cosmos-SDK wrong Block.Header.LastResultsHash it is totally blows my mind, i got error
7:49PM INF committed state app_hash=F839B3EA4DC197AD214F7448EFFA3EB1BB850ABB8AF4B690B441CF706C7BA915

height=13257 module=state num_txs=1 panic: Failed to process committed block (13258:78A87F5E0CAE0391A9A3DBCD961460BBB8BE0B811DDF3D50544B855DF264FB64): wrong Block.Header.LastResultsHash.

Expected 8506B0BD2A9D9C937A487FAEBFA118081458E7D9A5B6B86BC7417AFA751939C3,

got CA1650098D49306DC6139DA6A90ED10D9C543C57ACEACA24EB309254B9E03E43

when i try to start p2p session with my cosmos application
appd start --p2p.persistent_peers

is there any ideas how to resolve it?
version:

go: go version go1.17.11 darwin/arm64 build_deps:

*

*filippo.io/edwards25519@v1.0.0-beta.2

*github.com/99designs/keyring@v1.1.6

*github.com/ChainSafe/go-schnorrkel@v0.0.0-20200405005733-88cbf1b4c40d

*github.com/Workiva/go-datastructures@v1.0.52

*github.com/armon/go-metrics@v0.3.9

*github.com/beorn7/perks@v1.0.1

*github.com/bgentry/speakeasy@v0.1.0

*github.com/btcsuite/btcd@v0.22.0-beta

*github.com/cespare/xxhash/v2@v2.1.1

*github.com/coinbase/rosetta-sdk-go@v0.6.10

*github.com/confio/ics23/go@v0.6.6

*github.com/cosmos/btcutil@v1.0.4

*github.com/cosmos/cosmos-sdk@v0.44.5

*github.com/cosmos/go-bip39@v1.0.0

*github.com/cosmos/iavl@v0.17.3

*github.com/cosmos/ibc-go/v2@v2.0.2

*github.com/davecgh/go-spew@v1.1.1

*github.com/desertbit/timer@v0.0.0-20180107155436-c41aec40b27f

*github.com/dvsekhvalnov/jose2go@v0.0.0-20200901110807-248326c1351b

*github.com/felixge/httpsnoop@v1.0.1

*github.com/fsnotify/fsnotify@v1.5.1

*github.com/go-kit/kit@v0.10.0

*github.com/go-logfmt/logfmt@v0.5.0

*github.com/gogo/gateway@v1.1.0

*github.com/gogo/protobuf@v1.3.3 => github.com/regen-network/protobuf@v1.3.3-alpha.regen.1

*github.com/golang/protobuf@v1.5.2

*github.com/golang/snappy@v0.0.3

*github.com/google/btree@v1.0.0

*github.com/google/orderedcode@v0.0.1

*github.com/gorilla/handlers@v1.5.1

*github.com/gorilla/mux@v1.8.0

*github.com/gorilla/websocket@v1.4.2

*github.com/grpc-ecosystem/go-grpc-middleware@v1.3.0

*github.com/grpc-ecosystem/grpc-gateway@v1.16.0

*github.com/gtank/merlin@v0.1.1

*github.com/gtank/ristretto255@v0.1.2

*github.com/hashicorp/go-immutable-radix@v1.0.0

*github.com/hashicorp/golang-lru@v0.5.4

*github.com/hashicorp/hcl@v1.0.0

*github.com/hdevalence/ed25519consensus@v0.0.0-20210204194344-59a8610d2b87

*github.com/improbable-eng/grpc-web@v0.14.1

*github.com/keybase/go-keychain@v0.0.0-20190712205309-48d3d31d256d => github.com/99designs/go-keychain@v0.0.0-20191008050251-8e49817e8af4

*github.com/klauspost/compress@v1.11.13

*github.com/lib/pq@v1.10.2

*github.com/libp2p/go-buffer-pool@v0.0.2

*github.com/magiconair/properties@v1.8.5

*github.com/mattn/go-isatty@v0.0.14

*github.com/matttproud/golang_protobuf_extensions@v1.0.2-0.20181231171920-c182affec369

*github.com/mimoo/StrobeGo@v0.0.0-20181016162300-f8f6d4d2b643

*github.com/minio/highwayhash@v1.0.1

*github.com/mitchellh/go-homedir@v1.1.0

*github.com/mitchellh/mapstructure@v1.4.2

*github.com/mtibben/percent@v0.2.1

*github.com/pelletier/go-toml@v1.9.4

*github.com/pkg/errors@v0.9.1

*github.com/pmezard/go-difflib@v1.0.0

*github.com/prometheus/client_golang@v1.11.0

*github.com/prometheus/client_model@v0.2.0

*github.com/prometheus/common@v0.29.0

*github.com/prometheus/procfs@v0.6.0

*github.com/rakyll/statik@v0.1.7

*github.com/rcrowley/go-metrics@v0.0.0-20200313005456-10cdbea86bc0

*github.com/regen-network/cosmos-proto@v0.3.1

*github.com/rs/cors@v1.7.0

*github.com/rs/zerolog@v1.23.0

*github.com/spf13/afero@v1.6.0

*github.com/spf13/cast@v1.4.1

*github.com/spf13/cobra@v1.2.1

*github.com/spf13/jwalterweatherman@v1.1.0

*github.com/spf13/pflag@v1.0.5

*github.com/spf13/viper@v1.8.1

*github.com/stretchr/testify@v1.7.0

*github.com/subosito/gotenv@v1.2.0

*github.com/syndtr/goleveldb@v1.0.1-0.20200815110645-5c35d600f0ca

*github.com/tendermint/btcd@v0.1.1

*github.com/tendermint/crypto@v0.0.0-20191022145703-50d29ede1e15

*github.com/tendermint/go-amino@v0.16.0

*github.com/tendermint/starport@v0.19.2

*github.com/tendermint/tendermint@v0.34.14

*github.com/tendermint/tm-db@v0.6.4

*golang.org/x/crypto@v0.0.0-20210817164053-32db794688a5

*golang.org/x/net@v0.0.0-20220127200216-cd36cc0744dd

*golang.org/x/sys@v0.0.0-20211216021012-1d35b9e2eb4e

*golang.org/x/term@v0.0.0-20210927222741-03fcf44c2211

*golang.org/x/text@v0.3.7

*google.golang.org/genproto@v0.0.0-20220519153652-3a47de7e79bd

*google.golang.org/grpc@v1.46.2 => google.golang.org/grpc@v1.33.2

*google.golang.org/protobuf@v1.28.0

*gopkg.in/ini.v1@v1.63.2

*gopkg.in/yaml.v2@v2.4.0

*gopkg.in/yaml.v3@v3.0.1

*nhooyr.io/websocket@v1.8.6 cosmos_sdk_version: v0.44.5

none of this answers not helps me https://stackoverflow.com/a/69955551


text:
Senior Policy Officer (full-time / part-time)
Organisation : Penington Institute
Location : Melbourne (Carlton)
Work type : Full-time, Part-time
Profession : Advocacy, Policy & Research
Sector : Drug, Alcohol & Addiction
Organisation Name : Penington Institute
Penington Institute, an independent and not-for-profit organisation, actively supports the adoption of approaches to drug use that promote safety and human dignity. It does so through thought leadership, community education, front-line worker training, research and policy formation.
The successful candidate will work as part of a small and high-functioning team that reports to, and collaborates with, the Manager, Research and Policy on strategic policy, research and advocacy activities.
Take a proactive role in identifying and staying informed about policy issues relevant to drug use.
Draft high quality submissions and reports to government, the Executive, key strategic committees and other stakeholders.
Engage with key stakeholders to keep abreast of developments and intelligence from front-line workforces and various networks.
Source and analyse relevant policy, research and data, presenting recommendations to ensure that Penington Institute makes well-informed, evidence-based decisions.
Write content on policy issues for our publications (media releases, websites, publications and campaign materials).
Contribute to other projects as required.
We offer a dynamic working environment and are located in Carlton, in the heart of the vibrant Lygon St precinct.
The position is a full-time or negotiated part-time contract for two years. The remuneration package will be negotiated with the successful applicant.
Please read the full position description here.
For further information on this position, please contact Dr Karen Gelb on +613 9650 0699.
Applications close on Monday 31 January 2022 at 5pm; you are encouraged to apply as early as possible.
Position Description : Senior Policy Officer PD (Dec 2021)
Ensure your application includes a cover letter addressing the selection criteria and current CV.
Submit your application to Anna Rolle, a.rolle@penington.org.au.
Please quote in application: Senior Policy Officer (full-time / part-time) via Pro Bono Australia.
Profession: #Advocacy, #Policy_and_Research
Sector: #Drug_Alcohol_and_Addiction
Individual Giving Officer (FCD.46)
The Individual Giving Officer plays a vital role in the exec...
Graduate Lawyer: Legal Education and Reform
This is an opportunity to support the welfare of older Austr...
Yes we're lawyers, but we do a lot more....


NEXT Canada has launched applications for its 2018 Next Founders program.
Next Founders will accept 20 founders for its May 2018 program. It promises a network of entrepreneurs and interactive education sessions, while eligible companies have the chance to receive $30,000 in non-dilutive funding.


What is Get Out the Vote?
Every four years since 2000, AIGA, the professional association for design, has been activating design communities around the country to help motivate the American public to turn out to vote in the general election. Their Get Out the Vote campaign is a widely collaborative nonpartisan effort that consists of posters, organized exhibitions, and local chapter events. It is just one part of AIGA's Design for Democracy initiative, which aims to increase civic participation through design.
At New Kind, we view ourselves as community catalysts. So when AIGA invited us to participate in the GOTV campaign by creating a poster of our own, we didn't hesitate.
During our brainstorming phase, Craig and I considered different visual styles, messaging, and imagery that might satisfy all of our criteria, and it became clear just how difficult it can be to call people to action. Although plenty of our ideas were strong, fun, and interesting, finding one we were confident would actually move people proved to be tough.
One of our biggest struggles was: how do we tell people something they haven't already heard a thousand times? How do we break through to people who have their propaganda shields up or have already made up their mind not to vote?
We decided to tell them the last thing they expected to hear: Don't vote.
That would be our message in huge, bold, vibrant letters. Better yet, it would look like the only words on the poster at first glance. But underneath, in fine print, we would add tons of different reasons to vote, reinforcing the fact that if you care about literally anything, you had better get yourself to that booth.
With help from the entire New Kind team, Craig and I collected a list of polarizing issues and topics relevant to this year's election, making sure that we had enough of an assortment to stay nonpartisan. The matter we are addressing with this poster may be dead serious, but at New Kind we're all about letting our humanity show, so we didn't limit ourselves to political issues. We also wanted to be clear that even those who don't care at all about politics still have plenty of reasons to make sure to vote. With a healthy dash of wit and sarcasm, we mixed together a fine print that includes everything from human rights and the pursuit of happiness to tacos and puppies. There's something there for everybody.
It may seem like a small side project compared to some of our larger client campaigns, but we cherish the opportunity to flex our creative muscles through impact oriented work. In this case, it happens to be for a cause that we are all very passionate about.
We want to make sure we're doing our part to help design the future, and participating in AIGA's GOTV campaign has been a challenging and rewarding path down that road. Our GOTV poster was hung in curated exhibitions at this year's political conventions and was recently featured on ideas.ted.com (yes, that TED). You can also view it among all the other great poster entries over on the AIGA website.
Now make sure you're registered and GO VOTE. There's still time, so no excuses. If you'd like a digital copy of our poster, you can download it for free.


text:
Fiona Loke
Three Biodesign Founders Reflect on their Journeys
Photo courtesy of Iris Tan Three of the Biodesign founders, (L to R) Ginger Graham, John Abele, and Bob Croce, graciously took the time to visit and speak with the Biodesign fellows a few weeks ago. From the depth of their combined wisdom and experience came many pearls about career, medical device innovation, and life.
It was slightly disconcerting to me, and possibly other aspiring medtech entrepreneurs, that Bob, Ginger and John had not nailed down medtech entrepreneurship as a career choice early in life. The sort of certainty that seems to be a requirement, or at least is greatly encouraged on university applications (think about all those essays starting with "My first-ever toy was Legos. I've wanted to be an engineer since before I could crawl.") seemed suspiciously absent when they set off on their journeys. John sold light bulbs. Ginger wanted to be a veterinarian. And Bob had no idea what he wanted to do.
From this seemingly inauspicious beginning, however, emerged three giants in the medtech industry. For those of us just starting out, they offered several useful tips on career choices. "Pick your boss, not your job. Go where you can grow," exhorted Ginger. The most important gift you can get for your career? "Brutal, honest feedback," she said, and recommended a job in sales for a start, to nods from the others. "A sales job helps you understand tomorrow's problems – even if they're not expressed," added John. Indeed, the founders agreed that every job is a sales job. Whether customers are internal or external, it is crucial to understand how people make decisions. Overqualified or uninterested? "Attend sales school," suggested Bob as an alternative way to get exposure. John, a good connector, emphasized the value of finding the right partner for innovation. And Bob had some unconventional words of wisdom: "To be successful, do what you're supposed to do." That made no sense until he explained that people who get trained to do a job often start to take shortcuts as time goes by. Doing it right, said Bob, was the key.
Moving Ahead
For those itching to get on the fast track up the ladder, Bob had this to say: "If you're respected by those who report to you, you're respected by your peers, and you're respected by those you report to, you will get ahead." Giving employees a lot of responsibility but no authority was a good test of their ability to influence others, he revealed. So if you're in the rank and file, the next time the boss makes you organize the year-end company party, don't complain – you just might be in line for a promotion. Bob also talked about the value of niche markets. "There's a danger for venture-funded companies," he said. "They want the biggest market first, but customers are harder on you if you make a mistake there." In niche markets, he explained, customers become your partners and can even help you design your product.
If you're eyeing an MBA, but wondering what value it could bring, chew on the panel's insights on formal education versus experience. Ginger talked about getting frustrated in her company because there were several suggestions she made that couldn't be implemented. Going to business school helped her to understand what could and could not be done in the company. But that degree alone is not a path to success. "Get an MBA if it helps your confidence," she advised, while noting that performance and competence are valued more. Forming a network emerged as an equally important activity. The reason? "Change happens, and that's an opportunity," said John. Becoming a node in a network, the go-to person for link-ups to others, put him in a unique position to know, early on, what new projects people were working on.
So what did the panel think would be the next big thing? In a word, ageing, according to Ginger. "It's a big umbrella. It affects everything." The rise of individualized, mobile healthcare, combined with advances in next-generation genetic sequencing allowing the integration of a genomic response to therapy, was Ginger's pick for the biggest healthcare trend currently. But she also recognized that the delivery of that healthcare would become increasingly important. John identified multi-modality diagnostic imaging technologies and image fusion as the most exciting areas for this time. The ability of an image to convey the relationships within data, and the tools to do that, would be important and lead to disruptive change, he said. For those who want to read more on the concept of disruptive technology, John recommended Clayton Christenson's "The Innovator's Prescription".
Making Tough Decisions
A question was raised: What were the toughest decisions the founders had to make, and what were some things they said "no" to? Bob started the discussion by sharing that the toughest decisions he had to make usually involved people. For example, cutting a non-performing member from the team, rather than doing their job for them, was hard. John added that sometimes, we misjudge the integrity of a potential partner and – worse – our ability to change them. With Ginger, when she said "no" to something, it was because of personal internal conflict. She shared that as a vet, she was constantly battling customers' wishes that were not in the best interests of their pets. So, she left that profession.
On Medtech
Asked to comment on the current atmosphere of doom and gloom in the medtech industry, the founders took the wider view that this was part of the cyclical industry trend. "True innovations that change the quality and cost of healthcare are still needed," affirmed Ginger. Smart angels, she pointed out, offered many opportunities for unique funding. With regulatory hurdles mounting, some companies were forced to half-step off the FDA pathways and turn instead to alternative entry points to market, such as by offering medical foods and nutritional supplements.
My biggest takeaway from the session was that you don't pick the medtech industry – the industry picks you. Becoming the type of person who listens to someone's needs, who does it right, who doesn't take shortcuts, who sticks out the down times, builds relationships and isn't afraid to make tough decisions makes you the right choice – in any industry. And sooner or later, the medtech community recognizes that and somebody pulls you in, just as it did with Ginger, John and Bob.
From: Biodesign History, Lessons Learned
One response to Three Biodesign Founders Reflect on their Journeys
Letter from the President, 2012 « Biodesign Alumni
[…] Event was exceptional. Our alums had the opportunity to sit down with medtech legends such as John Abele, Ginger Graham, Bobe Croce, Eberhard Grube, and Simon Stertzer. Our Annual Event Panel Discussion with the Ardian Leadership team – including Andrew […]


text:
The Falcon and the Winter Soldier - Episode 2 - Review
Saturday, March 27, 2021 By Matt Vernier
Episode 2 of The Falcon and the Winter Soldier finally brought both titular characters together. Their relationship is a strained one, and it is predicated on the legacy of Steve Rogers. While Steve Rogers didn't appear in the episode, his presence is felt throughout the whole show in many different ways.
Sam and Bucky are living two very different lives, but they were brought back together by Captain America. Except this time it was the government chosen, generic white guy Captain America. John Walker (played by Wyatt Russell, son of Guardians of the Galaxy Vol 2 star Kurt Russell) got a bit of character development. He doesn't seem like a bad person. The only problem with him right now is that he's not Steve Rogers. He was tasked to do a job by the country he serves, and has all of this enormous baggage that comes with it.
The action sequence on top of the trucks was amazing. It was a worthy follow up to the airplane sequence from the first episode. If we get a big Marvel-esque battle every episode, we will be in good shape.
"Heart, humor, and spectacle" is often thrown around as requirements for a television episode. The spectacle is sort of ingrained into the DNA of the show already, just from it being a superhero fare.
The humor of course, comes from Bucky and Sam's strained relationship. The therapy scene is absolutely incredible, and one of the funniest (and awkward) things to happen in the MCU. This dynamic needs to remain in the show as much as all the action stuff.
As for the heart, well that is everywhere. It comes from Sam and Bucky of course, but it also came from the introduction of Isaiah Bradley. There is history with the Super Soldier Serum that the MCU hasn't explored yet. Bradley is a big part of that. This show is going to handle race like WandaVision handled grief. The scene with Isaiah, Sam and Bucky was just the start of that.
Overall, the episode moved well and gave sufficient time with all of its various pieces. It even gave a nice tease for Baron Zemo at the end - and one that surely promises to make the third episode something special.
New episodes of The Falcon and the Winter Soldier drop on Fridays, on Disney Plus.
Anthony Mackie Marvel MCU Reviews Sebastian Stan The Falcon and the Winter Soldier TV TV Reviews


text:
Q: How to trigger onShow callback for Keith Wood jQuery datepicker? Using Keith Wood's datepicker how can I trigger a callback before the datepicker is shown so I can set the picker's parameters?  Using the code below the callback (alert) is shown on page ready and not before the datepicker is shown.
$(function(){
   $( ".inputDatePick").datepick({ onShow: alert('on show callback') });
});

....

<input type="text" class="inputDatePick" />

A: doh!  the correct syntax for a callback is a function :
$(function(){
   $( ".inputDatePick").datepick({ onShow: function () { alert('on show callback') } });
});


OPT2JOB.COM - Career Maker is an emerging comprehensive technology job portal in USA, which offers valuable services for Optional Practical Training (OPT) student community. OPT2JOB is a job board and social network for OPT students to get connected with employers, trainers, other OPT student community and technical professionals. Our main goal is to assist OPT students in finding the right job based on their skills.
On OPT2JOB.com, you can post more than one resume to highlight specific skills that you can use for a specific job. Employers are very particular about what you highlight in your resume; a plain generic resume may not get your foot in door these days. You have to tailor your resume to highlight your strengths that job demands, and more than one resume will give you that edge to really work your best to get the job faster. You can keep track of jobs you applied and resume, which you used for each job. This alone will save you tons of hours on daily basis in your job search. Click here to post your resume. Click here to post your resume.
OPT2JOB.com also serves as a social network for OPT students, where the students can join and discuss a vast community of other OPT students and keep up to date information on the market for OPT students. On OPT2JOB.com, OPT students can also find independent qualified trainers who can provide customized training to suite your particular needs. OPT2JOB helps students kick start their career by successfully connecting with employers.
Click here to find online training courses.
Create and post multiple resumes, keep track of them as you apply.
Students can search for jobs (Mostly IT), online training, training & placements, internships, view training material and interview questions.
Access to trainers and other technical experts, browse jobs posted by employers looking to hire OPT students.
Students can also search for employers in various locations by using our advanced search feature.
Get regular and valuable updates on the current Job market, Immigration news, Interview Q&A's.
Training demos and as needed counseling sessions.
Find H1B sponsor in your relevant field.
Click here to sign up and post your resume.


text:
A pektin (E440) egy heteropoliszacharid (szénhidrátokkal rokon vegyület), mely a magasabb rendű szárazföldi növények (húsos gyümölcsök például alma, körte; valamint húsos gyökerek például sárgarépa, murok) sejtfalából állítható elő. A pektint először Henri Braconnot írta le 1825-ben. A tiszta pektin a fehér és a világosbarna közti színű, alaktalan tömeg, amelynek íze és szaga nincsen; vízzel sűrű, kocsonyaszerű tömeggé lesz és ebből alkohollal ismét leválasztható. Salétromsavval melegítve, előbb cukorsav, azután nyálkasav képződik belőle.

Az élelmiszeriparban elsősorban gyümölcszselékben és lekvárokban, E440 néven széles körben alkalmazzák. Előfordulhat továbbá gyümölcsitalokban, tejtartalmú élelmiszerekben, zselés cukorkákban, valamint egyes diétás ételekben.

A pektin név a görög péktikosz (πηκτικός = olajat megkötő szer) szóból származik.

Felhasználása

A pektint az élelmiszeriparban zselésítőanyagként, térfogatnövelőként, valamint stabilizálószerként alkalmazzák.
A legtöbb esetben lekvárok, dzsemek zselésítésére használják, így javítva annak minőségét. Házi befőzéshez cukorral keverve kapható (egy kevés citromsav hozzáadásával a pH-egyensúly megtartása végett). Egyes országokban a befőzéshez a pektint tiszta, porított állapotban lehet beszerezni.
A hagyományos jellegű lekvár (60%-nál nagyobb cukor- és gyümölcstartalom) előállításához magas észtertartalmú pektint használnak. Alacsony észter-tartalmú pektin alacsony cukortartalmú (diétás) lekvárok készítéséhez ajánlott.
Az élelmiszerekben a pektint általában 0,5-1,0% koncentrációban alkalmazzák (a friss gyümölcsökben is ilyen arányban található meg).

Pékáruk esetén zsírok helyettesítésére használják.

A szervezetbe kerülve a pektin megváltoztatja a széklet víztartalmát, növeli a viszkozitását, ezért mind székrekedés, mind hasmenés kezelésére alkalmazható. Égési sérülések esetén vízmegkötő képessége miatt alkalmazzák. Mivel rengeteg vizet képes megkötni, elfogyasztás után a gyomorban megduzzad és ezzel csökkenti az éhségérzetet. Ennek a hatásának köszönhetően a fogyókúrázók előszeretettel vásárolják és fogyasztják.

Kozmetikumok elsősorban stabilizáló hatása miatt tartalmazzák.

Szivarok esetén a sodrás után megsérült dohányleveleket pektin segítségével össze lehet ragasztani.

Története

A pektint először Henri Braconnot írta le 1825-ben, bár lekvárkészítő hatása már évszázadokkal előtte is ismert volt. Alacsony pektintartalmú gyümölcsökből készült lekvárok esetén magas pektintartalmú gyümölcsök kivonatát adták a lekvárhoz, így az a megfelelő állagot érte el. Az élelmiszerek elkészítésének iparosodása idején hamar rájöttek, hogy almatörkölyből főzés során pektin nyerhető. Később, az 1920-as és 1930-as években már gyárakban állították elő a pektint, és nemcsak almatörkölyből, de például egyes citrusfélék héjából is. Régebben a pektin folyadék formájában került forgalomba, de napjainkban a könnyebb szállíthatóság, és kezelhetőség érdekében por formájában kapható.

Biológiai hatások

A természetben a pektin vízben nem oldódó protopektin formájában fordul elő a szárazföldi növények lágy részében található sejtek közötti lamellák között. Mennyisége és struktúrája nagymértékben függ a növény fajtájától, korától, és részétől. Az erősebb részek több pektint tartalmaznak.

A pektin az emberi étrendnek szerves összetevője, mivel majdnem az összes ember által fogyasztott növényben megtalálható. Az ember számára pektin nem tekinthető tápanyagforrásként, mert a vékonybélen szinte érintetlenül halad keresztül. A vastagbélben található baktériumok számára tápanyag-forrásként szolgál (rövid láncú zsírsavakra bontják le, melyek hosszú távon csökkentik a koleszterinszintet, mert gátolják a koleszterin felszívódását). A pektin rostjaihoz a cukormolekulák is képesek kötődni, így jóval lasabban szívódnak fel. Ezáltal nem lesz nagy a vércukorszint emelkedése.

Kémiai tulajdonságok

A pektin váza α-(1-4) kapcsolt -galakturonsav lineáris láncából áll. Ezt néhány helyen (1-2) kapcsolt -ramnóz helyettesíti. A ramnózhoz számos más természetes cukor kapcsolódik. Ezek főként -galaktóz, -arabinóz, -xilóz, de más cukrok is előfordulhatnak. A pektin vázában átlagosan minden 25. helyen fordul elő ramnóz.

Moláris tömege átlagosan 60-130 000 g/mol, mely az előállítás során használt alapanyagból, valamint az előállítás folyamatától függ.

Jegyzetek

Források

Az Európai Parlament és a Tanács 1333/2008/EK rendelete (2008. december 16.) az élelmiszer-adalékanyagokról
Codex Alimentarius - pectin
Science Toys - pectin
food-info.net - pectin

További információk
 Pektin használata lekvárkészítéskor

Poliszacharidok
Élelmiszer-adalékanyagok


This Saturday's Forest Lotto gives supporters the opportunity of winning an amazing estimated jackpot of £14million.
The jackpot is the largest total for some considerable time so fans are encouraged to get involved now to have a chance of scooping the massive prize.
Playing the Forest Lotto is a worthwhile cause for Reds fans at they will be helping nurture their team's stars of the future. All club proceeds from the lotto are donated directly to the Nottingham Forest academy.


text:
Strollers for the City
Founded in 2009 in France by a group of five fathers, BABYZEN was born out of an ambition to create a product that would make parenting easier. The idea came to Co-founder and CEO Julien Chaudeurge in 2001 when he bought a stroller for his newborn son. But when moving around the streets, he found it to be bulky and inconvenient.
Recognizing a need for a simple and more compact product, he quickly got to work with his father, Jean Michel, and created a new generation of strollers designed to fit the needs of today's urban landscape.
Xavier de Bure, Managing Director and another of the company's co-founders, is based in Hong Kong.
"Our mission is to create products to make the daily lives of parents easier and to help them reach their personal and family goals," he said.
In 2012, BABYZEN introduced YOYO, which has since then taken the industry by storm. This all-in-one stroller can transform into three modes, so it can be used from birth to toddler, and also as a car seat. As YOYO is designed specifically for urban parents, Hong Kong is the perfect landscape to showcase its capabilities and features.
"Mobility is something we often relate to in Hong Kong, and being able to manoeuvre around the city with ease is a huge consideration point for urban parents," said de Bure. YOYO is foldable and can even be carried as hand luggage on flights, making it ideal for travelling as well as everyday use.
The company's products are currently distributed in 85 countries across five continents, and over 2,600 retail points. de Bure said that they work closely with their partners around the world to ensure global brand consistency and that the key to success is to "understand your market, your consumers, and stay focused on what their needs are through thoughtful innovation."
BABYZEN has always had an office in Hong Kong as its regional headquarters. Since joining HKGCC in 2018, its staff members have participated in several events to keep them up-to-date on the ever-changing business environment.
"The growingly complicated international relations can sometimes be a challenge for smaller organizations such as ours, and HKGCC can help us make better decisions by offering information and clarity," de Bure said.
Company: BABYZEN
HKGCC Membership No.: HKB0544
Website: http://www.babyzen.com/


text: .. cmake-module:: ../../Modules/FindLAPACK.cmake