text:
Two dead, one injured in La Quinta 'domestic homicide'
Police responding to an unrelated traffic incident Sunday morning discovered two dead bodies in a home
Two dead, one injured in La Quinta 'domestic homicide' Police responding to an unrelated traffic incident Sunday morning discovered two dead bodies in a home Check out this story on desertsun.com: http://desert.sn/1wevwd5
Tatiana Sanchez, The Desert Sun Published 7:09 p.m. PT Oct. 19, 2014 | Updated 9:26 p.m. PT Oct. 19, 2014
Double homicide investigation underway in La Quinta cove
Crystal Chatham/The Desert Sun
Law enforcement personnel are on the 51500 block of Avenida Carranza while investigating a double homicide on Sunday, October 19, 2014 in the cove area of La Quinta, Calif. Crystal Chatham/The Desert Sun
The 51500 block of Avenida Carranza is blocked off at Calle Hidalgo while law enforcement personnel are on scene investigating a double homicide Sunday, October 19, 2014 in the cove area of La Quinta, Calif. Crystal Chatham/The Desert Sun
Law enforcement personnel investigating a double homicide on Sunday on the 51-500 block of Avenida Carranza in the cove area of La Quinta. (Photo: Crystal Chatham/The Desert Sun )Buy Photo
The Riverside County Sheriff's Department is on the scene of what it's calling a "domestic homicide" at a residence in the La Quinta cove, where police found two deceased males at about 3:30 a.m. Sunday.
Police were responding to an unrelated traffic incident near the 47-200 block of Washington Street at about 3:15 a.m., when they saw a suspicious vehicle nearby.
Officers found a woman in the vehicle but she was "injured and unresponsive," according to the sheriff's department. Police forced entry into the vehicle and the woman was transported to a local hospital.
La Quinta and Thermal police launched a preliminary investigation and found the woman had last been seen at a family gathering at a residence on the 51-500 block of Avenida Carranza in La Quinta.
When police arrived at the residence they found two deceased males, according to the sheriff's department. Police believe the woman and the two males were related.
Police blocked off Avenida Carranza at Calle Hidalgo and continued their investigation into Sunday night.
At about 8 p.m., officers could be seen canvassing the 51-500 block of Avenida Carranza as neighbors looked on.
The investigation is ongoing but Cpl. Steven Favero, spokesman for the sheriff's department, told The Desert Sun that "all involved suspects are accounted for."
Favero declined to elaborate on why it was being classified as a "domestic homicide."
"That's what we're putting out for now," he said.
The woman found in the vehicle is in stable but critical condition, Favero said.
The sheriff's department has not released the names of the parties involved or provided details on how they were injured.
The residence in which the incident occurred is located in a quiet, suburban neighborhood known as the La Quinta Cove. No major roads were closed while police carried out their investigation.
Anyone with information about the case was urged to contact Investigator Loureiro at the Central Homicide Unit at (760) 393-3524.
Read or Share this story: http://desert.sn/1wevwd5


text:
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North India Statesman: Hindi
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TRIGGER NEWS
Police Brutality: A tale of systemic violence and oppression
By Sakshi Bansal	 Last updated Aug 30, 2020
Police Brutality in TN
25th May 2020: George Floyd lost his life to police brutality in Minneapolis, United States. This led to a series of protests, a heavy outpouring of messages of solidarity, and created distress with the sad state of affairs.
Police Brutality in Tamilnadu
22nd June 2020: Jayaraj and Bennicks in the state of Tamilnadu in Tuticorin district were subjected to sodomy, third-degree torture where police took turns to trash the father-son duo for a petty crime of keeping their mobile shop open 15 minutes after the permitted time.
9th June 2020: Protesters gather in Nairobi, Kenya against the judicial killing of 15 people since the coronavirus lockdown (15th March). There have been reports of 31 people sustaining severe injuries due to police brutality. Then Pakistan, Brazil, Philippines, the list goes on.
One is perturbed by the 'widespread' and 'global nature' of these heinous acts, which is police brutality. Is it localized to a particular area? No, but there are some commonalities that all these separate yet interconnected incidents share. This is a blatant abuse of power by the Oppressor, and the oppressed in most cases belong to a racially, ethnically, economically disadvantageous group. Our discourse on police brutality, whether in India or outside, can't be completed without examining the communal and economic angles.
Both Jayaraj and Bennicks belong to a higher caste, but their economic status makes them vulnerable to police torture, without the fear of repercussions by their criminals. Had it been a large industrialist, violating the lockdown restrictions there wouldn't have been such an unfortunate incident.
The owners of a small mobile accessories shop were found to be keeping their shop open beyond the permitted hours. Jayaraj was rounded up by the police and taken into custody. Bennick's, his son, who was nearby, saw this with his friends and rushed to the nearest police station. There he witnessed his father getting beaten up ruthlessly by the police. When he questioned this, he too was taken into custody for interrogation, and his friends were asked to leave.
As per several eyewitnesses, reported by the Federal, excruciating cries of the duo could be heard in 500 meters of distance throughout the night. The next day when they were taken to hospital, their clothes were torn, and injuries bloodied their bodies. Rectal bleeding caused them to change clothes several times. Even though their state was disheveled, the hospital gave them a physically fit report due to police pressure.
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Furthermore, they were taken to the magistrate where the police kept threatening them, which prevented them from speaking for themselves. Finally, they were remanded and taken to a sub-jail where they succumbed to their injuries on 22nd June and 23rd June respectively.
Massive outrage on social media, as well as support from high profile Bollywood celebrities, outpoured. The Madras High court took suo-moto cognizance of the matter. A probe has been set up to inquire, and 25 lakhs have been given as compensation to the victim's family.
And all this was done to satisfy the protestors. The perpetrators of the crime have been merely suspended. Apart from some transfers, no severe action has been taken yet. This is no justice; it is merely a transfer of tyranny from one place to another.
The police have to be held accountable, their abuse of power needs to be punished, and reform for the whole system of police is required in order to decrease the instances of police brutality in the future. Just in 2019, 1731 people died of police brutality, as reported by an independent study by a broad of NGO's. Worldwide, the instances of Police Brutality have been harrowing. These are just reported Statistics, so many of them are brushed off as natural deaths or covered by using the same influence and power, which causes these deaths in the first place.
Worldwide police officials and law enforcement are taking matters of law in their own hands. They have no right to do so when they are barely trained in law for a few months when mind you a lawyer spends 3-5 years and has to pass the Bar exam to show his proficiency in law.
Similarly, our movies and culture not only supports police brutality but glorifies it, leading to its normalization across the world. Movies like Singham and Dabang, with cops who consider themselves to be dispensaries of their own brand of justice, come to mind. When leaders in high position vow to protect the small, petty functionaries with half baked information about the law, then further add up to the legal protection that police have.
Police brutality is rooted in the mentality of the perpetrators of it, believing they are beyond law and justice, that they aren't in a position of servitude but that of unquestionable authority. Their atrocities also show the natural bias systemic of society we are a part of which for years has made certain groups more vulnerable to crimes. Dalits, Transgenders, racial minorities, migrant workers all their suffering in an interplay of power and oppression.
The next time when you hear about a migrant worker trashed by police, or a Muslim suspected to be a criminal or a black person rounded up by the police for a crime they didn't even commit.
images (69)Raise your voice, for it is the only way to change a system that has for years, created a divide.
George FloydJusticeforjayarajandfenixMadras high courtPolice brutalityRacismTamil naduTuticorin
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Sakshi Bansal
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भारत में हर नौकरी करने वाले को मिल सकती है ग्रेच्युटी
Peace Mediation: US, UAE, and ISRAEL
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redpajama_set_name: RedPajamaCommonCrawl


Running a Radio Mail Server (RMS) gateway station is rewarding. Actually saving a life or a boat in distress, helping medical missions in far off jungles, and participating on local public service and emergency communications teams are some of the ways sysops use their radio assets for the public good. Almost weekly one of the Winlink sysops will receive direct, heartfelt thanks from an incident victim or their loved ones. Sysops often assist with the evacuation of a sick yachtsman for emergency treatment, locate an overdue yacht for a worried family, or help arrange medical supplies for a remote medical clinic. Many sysops support their communities as part of a local emergency network. EmComm organizations train and drill member sysops and radio email operators for emergency field deployments. Off the amateur bands, Winlink is a mainstay in MARS, SHARES, and is a last-resort communication tool for national, regional and local governments, NGOs and agencies. Our sysops often remark that their work with WL2K is the most deeply rewarding thing they do in amateur radio.
We invite you to set up an RMS gateway station and join us.
Before you inquire to run an RMS gateway station, you must first be an active user of radio email. This is a firm pre-requisite. All gateway software requires a Winlink password. To get one you must maintain an active radio email account for each callsign/license you use as a gateway. In addition, you must also request authorization for your station to connect with CMS servers as a network gateway. This is explained below under 'Authorizations'.
to monitor Winlink e-mail for the gateway account daily, and to respond promptly to both Winlink users and members of the Winlink Development Team.
Sysops are responsible for the lawful operation of their stations. RMS gateways that remain off-line or do not report to WL2K Servers for extended periods, or fail to operate with current software, or operate in violation of their licenses are automatically removed from the network first, then issues are worked out. Portable or temporary stations should be tested on a regular basis to maintain their readiness. If they do not, they are also automatically purged.
Your operation of an RMS gateway station constitutes your implied agreement to these guidelines as published here. Administrators may refuse network connections from stations that do not observe these guidelines.
Your name and call sign.
The base call sign of the gateway station. This callsign must be under your direct control as licensee or trustee.
State your agreement to operate within these guidelines.
A reference to confirm your affiliation with an EmComm organization, if you intend to operate the station as a temporary or portable asset.
If your request is for a club station or a call sign that you do not control, have the trustee or the legal licensee make the request. As is only proper, we issue station authorizations to the person who is legally licensed. Only they may provide operational rights to other individuals. For any other special or temporary use outside normal 24/7 operations, whether individual or by a recognized emergency communications organization, please contact Steve Waterman, K4CJX, the Winlink 2000 administrator.


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Q: Insert Row between two rows We are using ASP.NET 1.1 for a website development, using DataGrid control for showing data.
Can some body suggest how can i insert rows in between two rows in datagrid control.
Thanks,
-Narendra

A: You'll have to insert that row in your data source - perhaps a DataTable.
Then you'll have to ensure that the grid is sorted as per your requirement. You're wanting the new row in a specific spot, so perhaps implement a SortOrder column on your DataTable, and explicitly update the values in that column for all the rows below the new row, as per your requirements, before binding.

A: You can insert the new row to the datasource (for example a DataTable).
DataRowCollection has a Function InsertAt that lets you insert rows at the position you want.
I will provide a simple example (in VB.Net with a GridView, DataGrid works the same):
ASPX:
 <asp:GridView ID="MyGrid" runat="server" AutoGenerateColumns="true">
        </asp:GridView>
        <asp:Button ID="BtnInsert" runat="server" Text="insert Obama at Position" /><asp:TextBox ID="TxtPosition" Text="0" runat="server"></asp:TextBox>

Codebehind:
   Protected Sub Page_Load(ByVal sender As Object, ByVal e As System.EventArgs) Handles Me.Load
        If Not IsPostBack Then
            BindData(getDataSource())
        End If
    End Sub

    Private Function getDataSource() As DataTable
        Dim tbl As New DataTable
        Dim col As New DataColumn("ID", GetType(Int32))
        tbl.Columns.Add(col)
        col = New DataColumn("FirstName", GetType(String))
        tbl.Columns.Add(col)
        col = New DataColumn("LastName", GetType(String))
        tbl.Columns.Add(col)
        Dim row As DataRow = tbl.NewRow
        row("ID") = 1
        row("FirstName") = "Benjamin"
        row("LastName") = "Franklin"
        tbl.Rows.Add(row)
        row = tbl.NewRow
        row("ID") = 2
        row("FirstName") = "Arnold"
        row("LastName") = "Schwarzenegger"
        tbl.Rows.Add(row)
        row = tbl.NewRow
        row("ID") = 3
        row("FirstName") = "Albert"
        row("LastName") = "Einstein"
        tbl.Rows.Add(row)
        row = tbl.NewRow
        row("ID") = 4
        row("FirstName") = "Bill"
        row("LastName") = "Gates"
        tbl.Rows.Add(row)
        Return tbl
    End Function

    Private Sub BindData(ByVal source As DataTable)
        Me.MyGrid.DataSource = source
        Me.MyGrid.DataBind()
    End Sub

    Private Sub BtnInsert_Click(ByVal sender As Object, ByVal e As System.EventArgs) Handles BtnInsert.Click
        Dim pos As Int32 = 0
        Int32.TryParse(TxtPosition.Text, pos)
        Dim source As DataTable = Me.getDataSource()
        If pos < 0 OrElse pos > source.Rows.Count Then pos = 0
        Dim row As DataRow = source.NewRow
        row("ID") = 5
        row("FirstName") = "Barack"
        row("LastName") = "Obama"
        source.Rows.InsertAt(row, pos)'this is the only important'
        BindData(source)
    End Sub

redpajama_set_name: RedPajamaStackExchange


After ten years of being away from the known La Sarthe Circuit, Toyota is now back on track for the Le Mans competing in the FIA World Endurance Championship with their new hybrid car, the Toyota TS030 HYBRID.
The car features a bred of pure racing hybrid engine that features unusual elements for endurance racing. Toyota's new TS030 HYBRID car is designed to give its drivers the extra performance they need on track while at the same time allowing its drivers to enjoy the benefits of fuel efficiency.
The Toyota TS030 HYBRID will start running in an electric mode. After a while, the driver will start dropping the clutch as a sign for the combustion engine to start kicking.
This new hybrid car of Toyota follows the iconic TS010 and TS020 cars, wherein both also had participated at Le Mans with success.
The TS030 HYBRID is designed to provide maximum performance and satisfaction to its drivers. The car carries the all-new V8 3.4 liter petrol engine and a hybrid system. Aisin AW is the maker of the car's front motor system while Toyota's official team partner DENSO created the rear motor system.
Like any other hybrid cars of Toyota, the TS030 has the ability to generate energy under braking and can be operated on a an electric-only mode producing zero carbon emission as well as zero fuel consumption, which is a big plus in keeping the environment clean and green.
TMG is the company taking charge in the developing of the TS030's brand new carbon fiber LMP1 chassis. TMG is also the place where the Toyota TS030 HYBRID is first assembled for the January 11-13, 2012 rollout at Paul Ricard.
At the French Track, drivers Alex Wurz, Nicolas Lapierre and Hiroaki Ishiura, the 30 years old Japanese driver who is also a candidate to join Toyota's driver line-up for the races tested the car and had it running in darkness. Successfully, the Toyota TS030 HYBRID were able to complete several hundred kilometers, which is an impressive level of performance and reliability.


text:
//
// Triple Play - utilities for use in PlayN-based games
// Copyright (c) 2011-2014, Three Rings Design, Inc. - All rights reserved.
// http://github.com/threerings/tripleplay/blob/master/LICENSE

package tripleplay.gesture;

import java.util.HashMap;
import java.util.Map;

import pythagoras.f.Point;

/**
 * A simple swipe gesture in a given cardinal direction. Supports 1 to 4 fingers. If greedy, will
 * indicate a continuous swipe. Completes if: one of the fingers stops moving or is removed from the
 * display. Cancels if an additional finger is added to the display or one of the fingers switches
 * directions.
 */
public class Swipe extends GestureBase<Swipe>
{
    public Swipe (Direction direction) {
        this(1, direction);
    }

    public Swipe (int touches, Direction direction) {
        if (touches < 1 || touches > 4) {
            Log.log.warning("How many fingers do you think people have?", "tapTouches", 4);
            touches = Math.max(1, Math.min(4, touches));
        }
        if (direction == null) {
            Log.log.warning("Swipe cannot operate with a null direction, assuming RIGHT");
            direction = Direction.RIGHT;
        }
        _touches = touches;
        setDirection(direction);
    }

    /**
     * If true (the default) a pause counts the same as a finger lifted from the display.
     */
    public Swipe cancelOnPause (boolean value) {
        _cancelOnPause = value;
        return this;
    }

    /**
     * A swipe is not qualified if the user moves outside of a region defined by lines that are
     * parallel to the line that goes through the start touch point along the direction axis.
     * offAxisTolerance is the distance away from that defining line that the parallel boundaries
     * sit. The default is 10 pixels. If you want the user to have more freedom in how finely
     * defined their swipes are, make the tolerance large.
     */
    public Swipe offAxisTolerance (int pixels) {
        _offAxisTolerance = pixels;
        return this;
    }

    /**
     * The distance on the Swipe's Direction axis that a touch must move to qualify the Swipe for
     * completion.
     */
    public Swipe onAxisThreshold (int pixels) {
        _onAxisThreshold = pixels;
        return this;
    }

    /**
     * An axis Swipe will consider any movement along the axis of its configured direction to be
     * valid, rather than only movement in the direction itself.
     */
    public Swipe axisSwipe (boolean value) {
        _axisSwipe = value;
        return this;
    }

    @Override protected void clearMemory () {
        _movedEnough = false;
        _startNodes.clear();
        _lastNodes.clear();
    }

    @Override protected void updateState (GestureNode node) {
        switch (node.type) {
        case START:
            _startNodes.put(node.touch.id, node);
            break;

        case MOVE:
            // always grounds for immediate dismissal
            if (_startNodes.size() != _touches) setState(State.UNQUALIFIED);
            evaluateMove(node);
            break;

        case PAUSE:
            if (_cancelOnPause) setState(getEndState());
            break;

        case END:
            setState(getEndState());
            break;

        case CANCEL:
            setState(State.UNQUALIFIED);
            break;
        }
    }

    protected State getEndState () {
        return _movedEnough && _startNodes.size() == _touches ? State.COMPLETE : State.UNQUALIFIED;
    }

    // TODO: any gesture that cares about swiping in a cardinal direction could make use of this
    protected void evaluateMove (GestureNode node) {
        GestureNode start = _startNodes.get(node.touch.id);
        if (start == null) {
            Log.log.warning("No start point for a path check, invalid state",
                "touchId", node.touch.id);
            return;
        }

        GestureNode lastNode = _lastNodes.get(node.touch.id);
        Point current = node.location;
        _lastNodes.put(node.touch.id, node);
        // we haven't moved far enough yet, no further evaluation needed.
        Point startLoc = start.location;
        if (current.distance(startLoc) < _onAxisThreshold) return;

        float offAxisDistance; // distance from our start position in the perpendicular axis
        float lastAxisDistance = axisDistance(
            lastNode == null ? null : lastNode.location, current);
        if (_direction == Direction.UP || _direction == Direction.DOWN)
            offAxisDistance = Math.abs(current.x() - startLoc.x());
        else
            offAxisDistance = Math.abs(current.y() - startLoc.y());

        // if we've strayed outside of the safe zone, or we've backtracked from our last position,
        // disqualify
        if (offAxisDistance > _offAxisTolerance) setState(State.UNQUALIFIED);
        else if (lastAxisDistance < 0) backtracked(node, -lastAxisDistance);

        // Figure out if we've moved enough to meet minimum requirements with all touches
        if (!_movedEnough) {
            boolean allMovedEnough = true;
            for (Map.Entry<Integer, GestureNode> touchStart : _startNodes.entrySet()) {
                GestureNode touchLast = _lastNodes.get(touchStart.getKey());
                Point lastLoc = touchLast == null ? null : touchLast.location;
                if (axisDistance(touchStart.getValue().location, lastLoc) <= _onAxisThreshold) {
                    allMovedEnough = false;
                    break;
                }
            }
            if (allMovedEnough) {
                _movedEnough = true;
                if (_greedy) setState(State.GREEDY);
            }
        }
    }

    protected float axisDistance (Point start, Point end) {
        if (start == null || end == null) return 0;

        float value;
        if (_direction == Direction.UP || _direction == Direction.DOWN)
            value = end.y() - start.y();
        else
            value = end.x() - start.x();
        return _axisSwipe ? Math.abs(value) : value * _directionModifier;
    }

    protected void backtracked (GestureNode node, float distance) {
        if (!_axisSwipe) {
            setState(State.UNQUALIFIED);
        }
    }

    protected void setDirection (Direction direction) {
        _direction = direction;
        _directionModifier = _direction == Direction.UP || _direction == Direction.LEFT ? -1 : 1;
    }

    protected int _touches;
    protected Direction _direction;
    protected int _directionModifier;

    protected boolean _movedEnough = false;
    protected Map<Integer, GestureNode> _startNodes = new HashMap<Integer, GestureNode>();
    protected Map<Integer, GestureNode> _lastNodes = new HashMap<Integer, GestureNode>();
    protected boolean _cancelOnPause = true;
    protected int _offAxisTolerance = 10;
    protected int _onAxisThreshold = 10;
    protected boolean _axisSwipe = false;
}

redpajama_set_name: RedPajamaGithub


Telos provides companies engaged in a process of corporate restructuring with its advice for the management of their strategic positioning and the dialogue with the Institutions, the political environment, productive categories and other stakeholders at both the national and the local level.
According to the needs and the specific requests of the client, the role of Telos can be limited to the drafting of analysis and strategic planning documents (e.g. analysis of the political-institutional framework, analysis of the decision-makers, strategic plan, position paper) or it can include a direct participation in formal negotiating processes (e.g. working groups established at all the relevant institutional levels).


text:
Atomic Force Microscopy Characterization of Cellulose Nanocrystals
Roya R. Lahiji, Purdue University - Main Campus
Xin Xu, Purdue University
R. Reifenberger, Birck Nanotechnology Center, Purdue University
Arvind Raman, Birck Nanotechnology Center, Purdue University
Alan Rudie, US Forest Service
Robert Moon, Purdue University - Main Campus
Langmuir, 2010, 26 (6), pp 4480–4488 DOI: 10.1021/la903111j
Roya R. Lahiji, Xin Xu, Ronald Reifenberger, Arvind Raman, Alan Rudie and Robert J. Moon. Atomic Force Microscopy Characterization of Cellulose Nanocrystals. Langmuir, 2010, 26 (6), pp 4480–4488 DOI: 10.1021/la903111j
Cellulose nanocrystals (CNCs) are gaining interest as a "green" nanomaterial with superior mechanical and chemical properties for high-performance nanocomposite materials; however, there is a lack of accurate material property characterization of individual CNCs. Here, a detailed Study of the topography, elastic and adhesive properties of individual wood-derived CNCs is performed using atomic force microscopy (AFM). AFM experiments involving high-resolution dynamic mode imaging and jump-mode measurements were performed on individual CNCs under ambient conditions with 30% relative humidity (RH) and under a N-2 atmosphere with 0.1% RH. A procedure was also developed to calculate the CNC transverse elastic modulus (E-T) by comparing the experimental force-distance curves measured on the CNCs with 3D finite element calculations of tip indentation on the CNC. The E-T of ail isolated CNC was estimated to be between 18 and 50 GPa at 0.1% RH; however, the associated crystallographic orientation of the CNC could not be determined. CNC properties were reasonably uniform along the entire CNC length, despite variations along the axis of 3-8 rim in CNC height. The range of RH used in this study was found to have a minimal effect oil the CNC geometry, confirming the resistance of the cellulose crystals to water penetration. CNC flexibility was also investigated by using the AFM tip as a nanomanipulator.


text:
MCHRI fuels diverse research through partnership with Stanford Diabetes Research Center
By Laura Hedli
Since 2016, MCHRI has partnered with the Stanford Diabetes Research Center (SDRC) to fund projects related to maternal and child health. By establishing an institutional commitment early on, SDRC has dramatically expanded by obtaining impactful federal funding and is supporting a wide array of projects in maternal and child health.
Transdisciplinary approach to modeling heart mechanics
Led by Associate Professor of Pediatrics and Bioengineering Alison Marsden, PhD, MCHRI TIP awardees combine mechanical and computational modeling with clinical data, leading to insights about pulmonary valve dysfunction.
5 Questions with Stanford's Preeclampsia Research Team
Lead by Co-PIs Drs. Virginia Winn, MD, PhD & Mark Hlatky, MD along with members from 12 Stanford Departments, this team recently received a $6 million grant from the NHLBI to study the connections between preeclampsia in pregnant women and heart diseases in later life.
Broad range of MCHRI awards support Faculty Scholar to understand and combat arboviral disease
MCHRI Faculty Scholar A. Desiree LaBeaud, MD, MS, associate professor of pediatrics, is looking at the risk factors and long-term health consequences of arboviral infections affecting children and pregnant women.
*APPLY NOW* MCHRI Eureka Certificate Course in Translational Medicine
MCHRI is excited to announce its inaugural translational medicine course, MCHRI Eureka 2020 Certificate Course in Translational Medicine. This 5-day intensive course will be held at Asilomar Conference Center in Monterey, CA from February, 9 to February 13, 2020.
Apply for funding opportunity in 22q11 Deletion Syndrome Research
The MCHRI Uytengsu-Hamilton 22q11 Neuropsychiatry Research Awards Program aims to promote research to improve the neurocognitive outcomes and behavioral symptoms of 22q11 Deletion Syndrome with immediate (within 5 years) and long term impact.
5 Questions: Dennis Wall on new discoveries in autism genetics
Autism researcher discusses the findings of an analysis of the genome sequences for 2,308 people from 493 nuclear families affected by autism.
Registration open for MCHRI symposium
Stanford scientists, clinicians and others with an interest in maternal and child health are invited to attend the free symposium on campus November 15.
Now accepting abstracts for 2nd Annual Research Symposium, November 15
MCHRI invites you to its second annual research symposium on Friday, November 15, 2019! We are now accepting all abstracts focused in maternal and child health research which will be reviewed and selected to present during our poster sessions. Read more.
Register now for the 2nd Annual Research Symposium, November 15
Registration is now open for the second annual Stanford Maternal and Child Health Research Institute Symposium, which will highlight the latest research in maternal and child health across campus.
Research in real life: Concussion, teen vaping, predicting prematurity
The Packard Children's News Spring issue features research, supported in part by MCHRI, on youth concussion, tobacco use among adolescents, non-invasive prenatal testing. Read more.
Stanford-led team receives $10 million award for myosin research
The NIGMS has awarded a five-year, $10 million grant to a multidisciplinary team of scientists led by Stanford researchers that will try to understand a common cause of heart failure.
Gender inequality and rigid norms linked with poor health, global research shows
Restrictive gender expectations hurt everyone's health, and understanding how this happens is the first step toward improving the situation around the world, according to a new series of papers published in The Lancet led by Gary Darmstadt, MD, professor of pediatrics and associate dean for maternal and child health.
A second chance at life
Two young brothers were born with IPEX syndrome, a life-threatening genetic disease that causes patients' immune systems to attack their own healthy tissues. Stanford physician-scientists and MCHRI awardees, Rosa Bacchetta, MD, and Alice Bertaina, MD, PhD, helped these brothers get a second chance at life.
Hormone reduces social impairment in kids with autism
Social behavior improved in children with autism after they inhaled a hormone called vasopressin, according to a pilot study led by Karen Parker, PhD, associate professor of psychiatry and behavioral sciences and Antonio Hardan, MD, professor of psychiatry and behavioral sciences. This research was supported by MCHRI.
New research links common brain injury in premature babies to specific cells
Stanford researchers have identified a specific set of brain cells that are particularly susceptible to harm from low oxygen exposure in early development. The work was led by Sergiu Pasca, MD, assistant professor of psychiatry and behavioral sciences, and Anca Pasca, MD, assistant professor of pediatrics. Both are MCHRI awardees.
Tobacco and e-cig promotions spark teens' use of nicotine products
Many teens own e-cigarette samples, coupons or branded promotional items, and these teens are more likely to try the products, a Stanford study found. Bonnie Halpern-Felsher, PhD, professor of pediatrics and MCHRI member, is the study's senior author.
Tad and Dianne Taube commit $6 million for pediatric cancer research
Philanthropists Tad and Dianne Taube have committed $6 million to the School of Medicine to establish the Taube Initiative in Pediatric Cancer Research. Their recent gifts include $1 million to support transdisciplinary research through MCHRI.
Women getting C-sections best judge of own pain medication needs
A recent research tested an approach that allowed women to choose the level of pain management they wanted during a cesarean section. MCHRI Faculty Scholar Brendan Carvalho, MD, professor of anesthesiology, perioperative and pain medicine, is lead author of the study.
How MCHRI is investing in research to reduce and prevent youth tobacco use
Teen vaping is on the rise and researchers are searching for solutions to reduce and prevent tobacco use. MCHRI is supporting investigators to research the effects of e-cigarettes on the brain and body and to provide resources aimed at preventing the use of tobacco and nicotine among youth.
How MCHRI supports research for clinician educator to improve the quality of care for patients and their families
MCHRI awarded Annette Nasr, RN, PhD, the Clinician Educator Grant to support her study in living donation and the long-term emotional and relationship impact for both the donor and the recipient.
Treating parasite infections during pregnancy thought to boost babies' immune responses
New research suggests that a specific change in prenatal care for pregnant women in developing countries may improve their babies' vaccine responsiveness after birth. Desiree LaBeaud, MD, associate professor of pediatrics and an MCHRI awardee, is the co-author of this work describing the findings.
With metabolic profiles of children, new center hopes to head off disease early
Stanford's new Metabolic Health Center aims to study metabolic profiles of babies, children, and pregnant women to understand the origins of disease. Co-directors include David K. Stevenson, MD, professor of pediatrics, and Karl Sylvester, MD, professor of pediatric surgery, who are MCHRI executive committee members.
Some viruses help protect harmful bacteria in cystic fibrosis patients
A recent study has shown some viruses help protect harmful bacteria in cystic fibrosis patients. Lead author, Elizabeth Burgener, MD, instructor of pediatrics, and co-authors, Paul Bollyky, MD, PhD, assistant professor of medicine and of microbiology and immunology, and Carlos Milla, MD, professor of pediatrics, were supported by MCHRI.
Stanford researchers outline the role of a deep brain structure in concussion
Through a combination of biometric tracking, simulated modeling and medical imaging, researchers detail how trauma to the side of the head cause concussion. This work was funded in part by MCHRI, with David Camarillo, PhD, assistant professor of bioengineering, as the co-lead author of the paper describing the findings.
Seed funding awarded at Pediatric Device Accelerator pitch competition
Last month, Stanford Children's Health, Stanford University School of Medicine, and MCHRI hosted the second annual Pediatric Innovation Showcase. The daylong event highlighted new devices and developments in pediatric medicine, as well as a pitch competition put on by the UCSF-Stanford Pediatric Device Consortium.
MCHRI provides support and 'second set of eyes' for investigator to make an impact in maternal health research
MCHRI awarded Stephanie Leonard, PhD, a postdoctoral fellowship and provided critical feedback during the review process to study the rise of pre-pregnancy health and cesarean delivery and the rise of life-threatening pregnancy complications.
Faculty Scholars explore impact of community-based intervention in the Tenderloin
Can teaching growth mindset to parents help alter their children's behavior and learning? Irene Loe, MD, assistant professor of pediatrics, and Claudia Mueller, MD, associate professor of pediatric surgery, aim to find out in their collaborative research project based at a Bay Area elementary school.
Developmental origins and emerging therapeutic opportunities for childhood cancer
Cancer is the leading disease-related cause of death in children in developed countries. In a recent Nature Medicine article, Michelle Monje, MD, PhD, associate professor of neurology and neurological sciences and an MCHRI Faculty Scholar, is the co-author on this paper that reviews the developmental origins and emerging therapeutic opportunities for childhood cancer.
Set of genes predicts severity of dengue
Purvesh Khatri, PhD, associate professor of medicine and of biomedical data science, and Shirit Einav, MD, associate professor of medicine and of microbiology and immunology, are co-authors on a paper that have identified 20 genes that can predict an individual's likelihood of developing a severe form of dengue fever with about 80 percent accuracy. This project was supported by SPARK, a funded partner of the MCHRI.
Congenital heart babies more likely to develop heart conditions as adults
An infant born with a relatively simple heart defect is far more likely to develop heart problems as an adult, according to Stanford researchers. James Priest, assistant professor of pediatrics and an MCHRI awardee, is the senior author of the paper summarizing the findings from the research.
Why are women affected by life-threatening complications in pregnancy and childbirth
Since 2004, the rate of life-threatening pregnancy complications has more than doubled, affecting more than 50,000 women in the U.S. Stephanie Leonard, PhD, postdoctoral fellow in pediatrics and an MCHRI awardee, is the lead author on a new study that uses California-wide data to try to figure it out.
Engineered immune cells target broad range of pediatric solid tumors in mice
In mouse studies, a Stanford-led team has developed an engineered immune cell that eliminates several types of childhood tumors. The study includes senior author, Crystal Mackall, MD, professor of pediatrics and of medicine, and several authors who are members of the MCHRI.
Predicting, preventing preterm births
Each year, 15 million babies worldwide are born prematurely, arriving at least three weeks before their due dates. Stanford's top obstetricians, neonatologists, geneticists, microbiologists, immunologists, epidemiologists, health policy experts, and bioengineers are working together to help more babies arrive safely.
SPARK helps academic researchers bring new drugs for rare diseases to market
Stanford's fast-growing drug-development program and MCHRI's funded partner, SPARK, has given hundreds of academic researchers around the world the training and connections to get their discoveries out of labs and into the hands of doctors and patients. Read the news story and check Stanford Medicine's summer article about SPARK.
MCHRI creates patient kits for Stanford Children's Hospital
Over the summer, the MCHRI team learned about the need for art supplies at the Lucile Packard Children's Hospital Stanford, which are provided to patients to use throughout their stay. Through the Champions for Children program, the MCHRI set up an online registry campaign designed to collect materials from within the team and their associated communities.
Neuroimaging studies linked to neurological developmental challenges of extremely preterm infants
Results from the Neuroimaging and Neurodevelopmental Outcomes (NEURO) School Age Follow-Up Study were recently published in Pediatrics. Neonatologist and CHRI Faculty Scholar, Susan Hintz, MD, MS Epi, is the lead author on the paper.
Faculty Scholars lead the way in advancing pediatric cancer cellular therapy program
Pediatric hematologist/oncologists and CHRI Faculty Scholars, Kara Davis, DO, and Norman Lacayo, MD, are leading the way in developing cancer cellular therapy programs at Lucile Packard Children's Hospital Stanford to help patients, like Jesus Sanchez-Romero, receive life-saving treatments.
CHRI awardees Ricardo Dolmetsch and Sergiu Pasca venture into the emerging field of molecular psychiatry
Neuroscientists Ricardo Dolmetsch, PhD, and Sergiu Pasca, MD, each received funding from the CHRI early on to help support their collaborative and innovative work in understanding the development of human brain disorders.
Faculty Scholar shares experience in the Eureka program for translational medicine
The CHRI sponsored several Stanford faculty, including hematologist/oncologist Anupama Narla, MD, to attend a seven-day course in translational medicine at the Eureka Institute for Translational Medicine in Siracusa, Italy.
The long-term vision in science: Faculty Scholar finds her Eureka moment as a translational scientist
Psychiatrist and behavioral scientist Manpreet Singh, MD, MS, shares her journey as translational researcher and the impact of the multiple awards she has received from the CHRI in her work, including the most recent opportunity to attend an intensive course at the Eureka Institute for Translational Medicine in Siracusa, Italy.
CHRI Faculty Scholars team up to transform the science and treatment of concussion
David Camarillo, PhD and Gerald Grant, MD are among the nation's foremost concussion experts and teaming up to transform the science and treatment of head injuries. They are CHRI Faculty Scholars and have received several grants towards concussion-specific research efforts.
Transformative Science Requires Risk
Michelle Monje, the Anne T. and Robert M. Bass Endowed Faculty Scholar and recipient of several Child Health Research Institute grants, takes a dynamic approach to studying brain tumor growth and potential treatments.
Building successful futures: CHRI Transdisciplinary Initiatives Program awardee investigates the health of immigrant families and children
Fernando Mendoza, a professor of pediatrics and the primary investigator on a CHRI Transdisciplinary Initiatives Program (TIP) grant, explores the health and well-being of children in immigrant families in California, as well as the impact of federal, state, and local policies on health outcomes.
Older fathers associated with increased birth risks
A decade of data documenting live births in the U.S. links babies of older fathers with a variety of increased risks at birth according to a new study. Michael Eisenberg, MD, associate professor of urology and MCHRI member, is the senior author of the study.
5 Questions: What parents should know about poliolike illness
Small clusters of cases of infectious paralysis are occurring in young children across North America. Pediatric neurologist and MCHRI member, Keith Van Haren, MD is working to understand the disease.
'DNA origami' triggers tissue generation in early development
In trying to decipher the "DNA origami" responsible for the generation of transplantable human skin, Stanford researchers have uncovered a master regulatory hierarchy controlling tissue differentiation. Anthony Oro MD, PhD, professor of dermatology, is senior author of the study.
5 Questions: Progress in peanut-allergy immunotherapy
As immunotherapy for peanut allergy advances, Sharon Chinthrajah, MD, clinical associate professor of medicine and of pediatrics discusses what that means for parents, providers and the future of allergy treatments.
Home videos of children can be scored to diagnose autism
Short home videos can be used to diagnose autism in children, according to a new Stanford study. MCHRI awardee, Dennis Wall, PhD, associate professor of pediatrics and of biomedical data science is the senior author.
Understanding the link between preeclampsia and heart disease later in life
Mark Hlatky, professor of medicine and of health research and policy, Virginia Winn, MD, PhD, associate professor of obstetrics and gynecology and MCHRI Faculty Scholar, will lead an interdisciplinary study of the links.
'Chemo brain' caused by malfunction in three types of brain cells
Three types of cells in the brain's white matter show interwoven problems during the cognitive dysfunction that follows treatment with the cancer drug methotrexate, Stanford neuroscientists have found. Michelle Monje, associate professor of neurology and neurological sciences, is the senior author and an MCHRI Faculty Scholar.
CHRI Funds Six Biodesign Faculty Fellows
The CHRI has funded six Biodesign Faculty Fellows for fiscal year 2019. The Institute partners with the Stanford Biodesign Faculty Fellowship program to support motivated Stanford faculty members with advanced training and mentoring in health technology innovations and fund maternal and child health projects.
Turning molecules into medicine with SPARK
An article in Stanford Medicine magazine profiles SPARK, an international program founded at Stanford that provides training and connections to help turn lab discoveries into treatments. CHRI partners with SPARK to fund projects related to maternal and child health research.
Concussion researchers study head motion in high school football hits
A research team led by concussion experts and CHRI members, David Camarillo, PhD, and Gerald Grant, MD, is outfitting the players with mouthguards that measure the motion of the head during impacts sustained in practices and games.
Eight scientists awarded NIH grants for high-risk, high-reward research
Eight School of Medicine researchers, including several CHRI members and awardees, will receive $32 million over five years to fund explorations of cancer, the brain, the aging process, chromosomes and the development of cells.
CHRI Announcement: Funding Increase for the Postdoctoral Support Program FY 2019
The CHRI is pleased to announce an increase in funding through its Postdoctoral Support Program to match the campus-wide minimum for postdoctoral fellows.
Lucile Packard Children's Hospital Stanford among the nation's best pediatric hospitals
U.S. News & World Report once again ranks Lucile Packard Children's Hospital Stanford among the nation's best pediatric hospitals for the 14th consecutive year.
CHRI awards $800K to four Transdisciplinary Disciplinary Initiative Projects in 2018
The CHRI awards a total of $800,000 to four Transdisciplinary Disciplinary Initiative research projects led by teams from different schools to work together on innovative projects with significant impact in maternal and child health. Read more.
CHRI awards $3.3.M to 44 clinical fellows, postdocs, and master's students in 2018
The CHRI awards a total of $3,364,982 to 26 clinical trainees, 14 postdoctoral researchers, and 4 master's students who are pursuing clinical and translational research in maternal and child health. Read more.
CHRI awards over half a million dollars to 16 Pilot Grants in 2018
The CHRI awards a total of $541,026 to 16 pilot grants in three categories: Early Career Pilot grants for instructors and assistant professors, New Ideas grants for mid to senior investigators, and Clinician Educators grants for clinical instructors or above. Read more.
Inaugural research symposium set for November 16
The inaugural CHRI Symposium, scheduled for Friday, November 16th at the Stanford University Li Ka Shing Center for Learning & Knowledge, will highlight the latest developments in maternal child health research from across the campus. Registration is now open.
CHRI Announcement: New funding opportunity for instructors on NIH K-awards
The Instructor K Award Support provides supplemental support for instructors who pursue an NIH K-award. The CHRI will match departmental commitments of up to $25,000 per year, providing a total combined CHRI/departmental support of up to $50,000 per year for up to two years.
Scientists find possible autism biomarker in cerebrospinal fluid
In a recent study, Stanford scientists have found low levels of a hormone called vasopressin that are linked to low social ability in monkeys and to autism in children. CHRI awardee, Karen Parker, PhD, is the lead author of this study.
Brain scans yield more clues to autism
Children with autism have structural and functional abnormalities in the brain circuit that normally makes social interaction feel rewarding, according to a recent study. Vinod Menon, PhD, professor of psychiatry and behavioral sciences, is the senior author.
Google Glass helps kids with autism read facial expressions
Children with autism were able to improve their social skills by using a smartphone app paired with Google Glasses, according to a study led by senior author and CHRI member, Dennis Wall, PhD, associate professor of pediatrics and of biomedical data science.
Rosenkranz Prize winner hopes to develop malaria vaccine for pregnant women
Prasanna Jagannathan, MD, assistant professor of medicine, received the 2018 Rosenkranz Prize, which he hopes to use to develop a malaria vaccine for pregnant women. He received a CHRI award for his pilot work on malaria chemoprevention in pregnancy and transfer of antimalarial antibodies to newborns.
New CEO of Lucile Packard Foundation for Children's Health appointed
Cynthia Brandt Stover has been appointed president and CEO of the Lucile Packard Foundation for Children's Health. The foundation directs all fundraising for the Stanford Children's Hospital and for the maternal and child health programs at the School of Medicine.
Stanford study shows how head and neck positioning affects concussion risk
Stanford researchers are working with a model they developed in David Camarillo's lab to stimulate how head and neck positioning during an impact affects rotational acceleration resulting from the impact.
A closer look at the powerhouses of the cell, mitochondria
Daniel Bernstein, MD, the Alfred Woodley Salter and Mabel G. Salter Endowed Professor, recently gave a lecture at the CHRI Seminar Series on an imaging technique for assessing the diversity of mitochondria.
How Stanford research is making MRI scans safer for kids
Shreyas Vasanawala, professor of radiology, is tailoring MRI equipment to children. In this Q&A, he discusses how his work allows young patients to receive faster MRI exams that require less anesthesia.
Stanford Medicine honors Christopher Dawes, a transformational leader
The longtime CEO of Lucile Packard Children's Hospital Stanford, Christopher Dawes, has retired after nearly three decades of shaping health care for children and expectant mothers.
How blood will soon tell us everything
Recent studies show you can predict a woman's due date within a two-week window from a blood test. Bill Gates highlights the work of Stephen Quake, a professor of bioengineering and of applied physics, and how noninvasive blood tests are the future of health care.
The new, improved world of infant care
Six research centers are finding new ways to prevent premature birth, which affects one in 10 infants and can cause serious and costly mental and physical disabilities.
Blood test might predict pregnancy due date and preterm birth
A Stanford-led team has developed a blood test that can give a reliable estimate of the baby's due date and can predict if the baby will arrive prematurely. Study included co-senior author Stephen Quake, PhD, a professor of bioengineering and of applied physics.
Ms. Hosna Omarzad receives Donna Schurr Spirit Award
The CHRI is proud to announce Ms. Hosna Omarzad as the recipient of the 2018 Donna Schurr Spirit Award, given by the Department of Pediatrics at the Stanford School of Medicine for an outstanding staff member for their outstanding performance and dedication.
Genetic variation in progesterone receptor tied to prematurity risk
Humans have unexpectedly high genetic variation in the receptor for a key pregnancy-maintaining hormone, according to research led by Stanford scientist. Gary Shaw, DrPH, and David Stevenson, MD, both professors of pediatrics, share senior authorship of this study.
Separation from parents removes children's most important protection
Stanford psychologist Ian H. Gotlib discusses the psychological effects of early-life stress and parental separation. Gotlib's research has shown that children need their parents for their own emotional well-being.
A rare disease inspires a Stanford team to develop a new test
Fanconi anemia is a rare but deadly disease and there are no good drugs to treat its root cause, but Stanford researchers, including Eric Kool, PhD, and Kenneth Weinberg, MD, and collaborator Daria Mochly-Rosen, PhD, are developing a test that could help kids with the disease.
Dr. Yvonne Maldonado celebrated for her accomplishments in pediatric research
Yvonne Maldonado, MD, senior associate dean for faculty development and diversity and professor of pediatrics, is celebrated for her perseverance and accomplishments in pediatric research.
Dr. Crystal Mackall awarded $11.9M for anti-leukemia clinical trial
Crystal Mackall, professor of pediatrics and of medicine at the School of Medicine, was awarded $11.9 million by the California Institute for Regenerative Medicine(CIRM) to fund a anti-leukemia clinical trial.
New Precision Health and Integrated Diagnostics Center sets out to stop disease before it starts
Officially established last year, the Stanford Precision Health and Integrated Diagnostics Center brings together scientists from across campus to focus on precision health and integrated diagnostics. The center's team of scientists includes members from the CHRI.
Health Innovation Opportunities for 2017-2018 Stanford Biodesign Faculty Fellows
The Stanford Biodesign Faculty Fellowship provides motivated Stanford University faculty members from the schools of Medicine and Engineering with advanced training and mentoring in health technology innovation. Six participants were partially funded by the CHRI.
Link between birth weight and adult metabolic health
New research examines the relationships between birth weight and metabolic and cardiovascular disease in adults. Thomas Robinson, MD, MPH, an expert in childhood obesity and a CHRI executive committee member, provides his take in the article.
Researchers team up to develop new life-saving antibiotics that will not cause deafness in children
Anthony Ricci, PhD, a professor of otolaryngology, and Alan Cheng, MD, an associate professor of otolaryngology, are developing new life-saving antibiotics that will not cause deafness in children. This project was supported by SPARK, funded in part by the CHRI for projects focused in maternal and child health. See article in Stanford Medicine magazine and blog post in Scope.
Countdown to Childx: Bioethics in pediatrics
The Childx conference, a TED-style event happening next week at Stanford, will feature a keynote session by bioethicist Jeffrey Kahn, PhD, director of the Johns Hopkins Berman Institute of Bioethics.
Stanford Childx 2018: Big ideas for little patients
Highlights from Childx, a cross-disciplinary science, medicine, public policy and healthcare symposium on research developments and opportunities for improving pediatric care.
Dr. Mary Leonard Receives Silicon Valley Tribute to Women Award
Mary Leonard, MD, MSCE, executive director of the CHRI, has been selected as one of the recipients of the 2018 YWCA Silicon Valley Tribute to Women. She is honored for her significant contributions to the Silicon Valley through their leadership in medicine and health care.
Altered immune cells clear childhood brain tumor in mice
Recent study published in Nature Medicine demonstrates the first time a severe brainstem cancer has been eradicated in mice with the tumor. The senior authors are CHRI members, Michelle Monje, MD, PhD and Crystal Mackall, MD.
Precision health and growth mindsets at Childx
The third Childx conference was held last week at Stanford, hosted by the Child Health Research Institute. Hundreds of pediatricians, educators, scientists and policy experts attended the TED-style event to address challenges and solutions in child health.
Using big data to understand the disappearing American dream at Childx
Stanford economist Raj Chetty, PhD, delivers his keynote session at last week's Childx conference on the American dream of children growing up to earn more than their parents is harder to achieve than it used to be.
Tackling childhood obesity at Childx
Speakers at Childx, including Stanford Medicine pediatrician Tom Robinson, MD, explore novel approaches to tackling the challenging issues in childhood obesity.
Stanford's Childx conference starts today. Jump in!
Today marks the start of Stanford's third Childx conference, a TED-style event addressing challenges and solutions in child health.
Upcoming Childx conference will highlight collaborative solutions in child health
Next month, experts from many fields will convene at Stanford's third Childx conference to discuss challenges and solutions in child health. Heidi Feldman, MD and David Cornfield, MD, co-chairs of the conference share insights on this year's event.
The complex nature of concussion
A recent report in Physical Review Letters look at the complex nature of concussion, led by a team working under David Camarillo, PhD, an assistant professor of bioengineering and a member of the CHRI.
Countdown to Childx: What doctors can do to improve health literacy
Health literacy means doctors explaining health care tasks - such as giving a child medication - in doable steps that don't make you feel like you're overwhelmed, says health-literacy expert Ruth Parker, a guest at next month's Childx conference.
Countdown to Childx: Medical device innovation for kids with chronic disease
Pediatric cardiologist and biomedical innovator Bronwyn Harris talks about the challenge of translating data into better outcomes for kids with chronic diseases. Dr. Harris will speak at the upcoming Childx conference.
Recent study suggest that pediatric obesity and depression are connected in the brain
Early-life obesity and depression may be driven by shared abnormalities in brain regions that process rewards, according to a recent study with lead authorship by Manpreet Singh, MD, assistant professor of psychiatry and behavioral sciences and a member of the CHRI.
Innovative ideas and research at the Stanford 2018 Childx
Over 30 speakers from bioengineering to psychology took the stage at the third Childx conference earlier this month on Stanford campus and delivered the latest developments and advancements in children's health.
Stanford team tests sleep monitoring for asthma patients
Pediatric pulmonologist and CHRI member, David Cornfield, MD and a group of colleagues are testing a new monitoring approach that uses data collected during sleep.
CHRI Funds Two Diabetes Research Center Seed Grants
The CHRI funded two Stanford Diabetes Research Center (SDRC) Pilot and Feasibility seed grants, one to Eric A. Appel, PhD and the other to H. Tom Soh, PhD, in support of maternal child health related research.
CHRI Introduces New Seminar Series
The Stanford Child Health Research Institute will officially launch a new seminar series starting March, highlighting current research and the latest developments in maternal child health.
The secret to building a strong heart lies in blood vessels
A recent study has linked a cardiovascular disease to poorly developed blood vessels around the heart in babies. The study included author Joseph Wu, MD, the Simon H. Stertzer professor of cardiovascular medicine, who has served as a mentor and co-investigator on several CHRI-funded awards.
Daniel Bernstein Named Associate Dean for Curriculum and Student Scholarship
Daniel Bernstein, MD, the Alfred Woodley Salter and Mabel G. Salter Professor of Pediatrics, has been appointed as the School of Medicine's Associate Dean for Curriculum and Student Scholarship. He serves as the co-chair of the Clinical Trainee Support funding program in the CHRI.
CHRI Funds Two Global Child Health Equity Seed Grants
The CHRI funded two Global Child Health Equity Seed Grants of $25,000 each to Jennifer Keller, PhD and Clea Sarnquist, DrPH, MPHM for projects seeking solutions to improve the health of pregnant women and children in low-resource settings.
Awardees Selected for Bridge Funding Support Progam
The CHRI awarded two Bridge Funding Support, one to Manisha Desai, PhD, and the other to Julie Parsonnet, MD, to aid in the continuation of their research projects in maternal child health.
Taube's Gift to Launch Youth Addition, Children's Concussion Initiatives
The Taube's combined gift of $14.5M will enable Gerald Grant, MD, associate professor of neurosurgery and David Camarillo, PhD, assistant professor of bioengineering to advance concussion education, care and research. They will speak about this topic at a champions reception the evening before the Childx conference.
CHRI co-sponsors 2nd annual Center for Definitive and Curative Medicine Symposium
With the support of the CHRI and the Lucile Packard Children's Hospital Stanford, the Center for Definitive and Curative Medicine Symposium put on this year's annual scientific conference.
Recent deployment linked to higher risk of premature delivery
Giving birth soon after military deployment is linked to greater risk of premature delivery, according to a study of U.S. servicewomen led by author Jonathan Shaw, MD, a member of the CHRI.
Researchers identify renegade cells that spur relapse in children with leukemia
Stanford researchers have published a paper in Nature Medicine that describes a technique to determine at diagnosis whether children with acute lymphoblastic leukemia would relapse. Authors included CHRI members Kara Davis, DO; Norman Lacayo, MD; Robert Tibshirani, PhD; Garry Nolan, PhD.
Dr. Crystal Mackall wins national award for cancer research
Crystal Mackall, MD and her co-investigators won a 2018 Top 10 Clinical Research Achievement Award for their research in pediatric cancer. Dr. Mackall is a member of the CHRI and recently spoke at the inaugural education seminar.
Brain Balls
Sergiu P. Pasca, MD has figured out how to grow brain-like blobs in lab dishes, which could give insights into the biology of neuropsychiatric diseases like autism and aid in the understanding of fetal brain development in other neurodevelopmental disorders.
Dr. Gary Shaw appointed to endowed position
Gary Shaw, DrPH, professor of pediatrics, has been appointed to an endowed position in the School of Medicine. Dr. Shaw is a CHRI member and serves as a panel chair on one of the Institute's funding programs.
David K. Stevenson Elected to the American Association for the Advancement of Science
David K. Stevenson, the Harold K. Faber Professor of Pediatrics and Co-Director of the Child Health Research Institute, was selected to the American Association for the Advancement of Science for his contributions in the field of neonatology and pediatrics.
Stanford Magazine Spotlight on Pediatric Care
The Fall 2017 issue of Stanford Medicine highlights the ways specialists are using the latest technology and treatments to put children and their families at the center of care. Read the full story and check out the magazine online.
The New Lucile Packard Children's Hospital Stanford
The Lucile Packard Children's Hospital Stanford opened its new main building and grounds on December 9. Designed to transform the patient and family experience, the new 521,000-square-foot building more than doubles the size of the existing pediatric and obstetric hospital campus.
Weight Gain Impact on Cardiovascular System
Stanford scientists have discovered how gaining weight changes your whole body, as described in a recent paper published online in Cell Systems. Senior authorship is shared by Michael Snyder, PhD, professor of genetics and co-investigator on a Stanford Cardiovascular Institute (CVI) seed grant sponsored by the CHRI; and Tracey McLaughlin, MD, professor of medicine, also a recipient of a CVI award funded by the CHRI.
Drug increases speed, safety of treatment for multiple food allergies
Kari Nadeau, MD, PhD, professor of medicine and of pediatrics and the director of the Sean N. Parker Center for Allergy and Asthma Research, is the co-author of this study where they looked at an asthma medication to treat children for food allergies.
California Stem Cell Agency Awards $5.6M in Grants to Anthony Oro
The California Institute for Regenerative Medicine awarded Anthony Oro, professor of dermatology and co-director of the CHRI, $5.6 million to support his work in developing new treatments for children with a blistering skin disease.
Higher blood sugar in early pregnancy raises baby's heart-defect risk
The study's senior author, James Priest, MD, assistant professor of pediatric cardiology and recipient of a CHRI sponsored Cardiovascular Institute (CVI) seed grant award, looks at the link between high blood sugar in early pregnancies and baby's risk for heart defects.
High-tech imaging could reveal mysteries of bone damage in kids with chronic disease
Mary Leonard, MD, professor and chair in the Department of Pediatrics at Stanford and the executive director of the CHRI, works to understand exactly how chronic diseases hurt children's bone health.
Interview with Carol S. Dweck on Growth Mindset
The Times Higher Education recently interviewed Carol S. Dweck, a Lewis and Virginia Eaton professor of psychology, on students' growth mindset. She is one of the keynote speakers for CHRI's upcoming sponsored event, the 2018 Childx Symposium.
The Future of Genome Editing in Human Diseases
Matthew Porteus, an associate professor of pediatrics and a CHRI-funded investigator, spoke before a U.S. Senate committee for hearing on "Gene Editing Technology: Innovation and Impact." Also present at the hearing was Jeffrey Kahn, the Director of the Johns Hopkins Berman Institute of Bioethics and a keynote speaker for CHRI-sponsored 2018 Childx Symposium.
Publication: Macrophage-released ADAMTS1 Promotes Muscle Stem Cell Activation
Nature Communications released a recent publication on a study, funded in part by the Child Health Research Institute, that examined how hormones play a role in muscle stem cells activation and the implications for muscle growth and regeneration. The team of Stanford researchers behind this study included Brian Feldman, an assistant professor of pediatrics and a CHRI-endowed Bechtel Faculty Scholar.
**NEW** CHRI Funds Global Child Health Seed Grants
The CHRI-sponsored Global Child Health Equity (GCHE) Seed Grant program aims to support two global health seed grants of up to $25,000 each for projects seeking solutions to improve the health of pregnant women and children in low-resource settings. Deadline for proposal submission has been extended to December 15, 2017.
Children of War
Paul Wise, a professor of pediatrics and core faculty member of the Stanford Center for Health Policy, is working with colleagues to address the needs of children in areas of unstable governance and civil war.
CHRI Funds 2018 Biodesign Faculty Fellowships
As of Fiscal Year 2018, Child Health Research Institute (CHRI) will fund 50% for maternal child health Biodesign Faculty Fellowships. The fellowship provides motivated Stanford faculty members from the schools of Medicine and Engineering with advanced training and mentoring in health technology innovation.
Anthony Oro Named Co-Director of the Child Health Research Institute
The Stanford Child Health Research Institute is proud to announce a new Co-Director, Anthony Oro, MD, PhD, the Eugene and Gloria Bauer Professor in the Department of Dermatology.
Use big data
Sociologist Karen Cook and other Stanford researchers are encouraging their colleagues who study social interaction to conduct studies that examine online environments and use big data.
David Schneider appointed chair of microbiology and immunology
David Schneider, whose research focuses on resilience to infection and developing mathematical models to predict recovery and well-being, succeeds Peter Sarnow in post.
Virtual Reality imaging technology gives surgeons a better view into patient anatomy
Radiologists and surgeons at Lucile Packard Children's Hospital Stanford are using new technology to generate easily manipulated 3-D images of patients' anatomy from flat CT and MRI scans.
The Virtual Heart
Stanford's David M. Axelrod, MD, and David A. Sarno of Lighthaus present at the CeBIT Global Conferences.
Watch the presentation on YouTube
Finding the cures within us
Stem cell research holds the promise of a sea change in medicine. At Stanford, momentum is building.
Read more in Stanford Magazine
American Society of Gene and Cell Therapy Awards Maria Grazia Roncarolo 2017 Outstanding Achievement Award
Roncarolo is being recognized for her many contributions to the field of gene and cell therapy, which she will describe in an award lecture on Friday, May 12 in Washington, DC as part of the organization's annual meeting.
View Maria Grazia Roncarolo's profile
Child Health Research Institute awards 26 grants for 2017
The Stanford institute's grant program funds projects that support innovative clinical and translational research on maternal and child health.
Gene therapy for blistering skin disease appears to enhance healing in clinical trial
A trial in which genetically altered skin was grafted onto patients' chronic wounds marks the first time that skin-based gene therapy has been demonstrated to be safe and effective in humans.
5 Questions: Halpern-Felsher on teens' misconceptions about marijuana
A survey of hundreds of California high-school students shows that teens don't understand the risks of marijuana use, and are more likely to smoke it if they have seen marijuana ads.
Researchers take step toward gene therapy for sickle cell disease
Using the CRISPR gene-editing technique in stem cells, Stanford researchers repaired the gene that causes sickle cell disease, and the mended stem cells were successfully transplanted into mice.
Traumatic stress changes brains of boys, girls differently
A brain region that integrates emotions and actions appears to undergo accelerated maturation in adolescent girls with PTSD, but not in boys with the condition, a Stanford study has found.
Stanford patient was first to receive lifesaving drug as an infant
Four-year-old Zoe Harting is doing well after participating in a phase-2 clinical trial of the first drug for a deadly genetic disease, spinal muscular atrophy type 1.
What Happened Within This Player's Skull
Information from mouth guard sensors, developed by bioengineer David Camarillo and his team at the Cam Lab, provide a more detailed and precise window into what was happening within a football player's brain within milliseconds after a hit.
Read the NY Times Article
Stanford researchers expand comparison of males and females with anorexia
Recently, a team of researchers from Stanford and other universities have published a series of papers to help fill this knowledge gap.
Read more on ScopeBlog
Diabetes hampers activity of bone stem cells, Stanford researchers find
In a study, a team of Stanford researchers reveal the reason for the impairment and demonstrate a potential solution.
Obstetricians balk at FDA warning on anesthesia in pregnant women
The FDA recently issued a safety warning that repeated or lengthy use of general anesthetic in pregnant women in their third trimester could damage children's developing brains. Maurice Druzin, MD, provides comment.
Conjoined twins successfully separated at Packard Children's Hospital
Two-year-old twin sisters Erika and Eva Sandoval are recovering in the pediatric intensive care unit following their Dec. 6 separation surgery.
Researchers develop new compound to reduce tumor growth
Researchers at Stanford found that a new cell surface receptor they created is effective at inhibiting cancer growth in mice.
Could Antidepressant Combat Lethal Lung Cancer
An older and little-used class of antidepressants may help combat a particularly deadly form of lung cancer, according to a study by Julien Sage, PhD.
Learn more from MedicineNet


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Small Victories: The True Story of Faith No More – Book Review
Posted on October 8, 2018 by Hilary Mahoney
Type in a search for "Faith No More books" on your favorite search engine or online store. There will be a surprisingly short list- one came out in 1994 and therefore leaves much of the story still to be discovered, one (The Faith No More and Mr. Bungle Companion) which was also reviewed here in Screamer covers more of the Mike Patton years of the band as well as Patton's other musical projects. Now with Small Victories: The True Story of Faith No More from Jawbone Press, Adrian Harte tells the most detailed story of the band to be found so far.
Harte runs the website Faith No More 2.0 and is clearly a fan in addition to a writer. Compiling hours and hours of interviews of his own, in addition to massive amounts of additional research, the author has split the books into four sections. The introduction gives the reader a taste of what's to come: "Since 1983, Faith No More have ingested elements of almost every musical style and flavoured them with their own musical musk to produce seven studio albums- music like no other." And the story is about to begin: "The Faith No More journey takes in 1970's suburban Los Angeles ennui, the 80's music underground of San Francisco, and the 90's MTV alternative music gold rush. It is the story of Faith No More as autarkic outsiders, as buzz band, as heavy metal miscasts, as reluctant arena act, as anaphasic relics, and as comeback kings for a day, fools for a lifetime."
Part One of the book covers the background of the core band members and how the band came into being. And so begins the revolving door list of guitar players that have been a part of the band throughout the years, and the reader may even be surprised to hear some of the names of players that were considered but didn't make the cut. Also included is that brief stint where Courtney Love was the singer. There is also a great amount of detail on former vocalist Chuck Mosley and all the antics that ensued during the early era of the band.
Mike Patton makes his debut in Part Two of the book and the author leads the reader through an in-depth history of the making of those iconic albums, touring years and the band's sudden unexpected stint as MTV darlings. Scattered throughout the book are pages of full color photos from all eras of the band, some from the band members' personal archives.
And yes, there is a Part Three as well as a Part Four of the book, but we can't give away everything now can we? Just know that Harte has definitely done his research. Unfortunately, Mike Patton would not be interviewed for the book, so quotes from him are from previously published interviews, but Mike Bordin, Roddy Bottum and Bill Gould were in full cooperation, offering their insights to the book. Unless or until Patton decides to offer his story, Small Victories is as close to the full story as a fan will find in one package.
New Book, 'The Faith No More & Mr. Bungle Companion,' Provides Overview/Analyzation Of Both Legendary Bands
THE FAITH NO MORE AND MR. BUNGLE COMPANION
Book Review: The Other Side of Rainbow by Greg Prato
New Scorpions Book Tells The Story Of Influential Era Of The Band


text:
A New Field of Health Careers is Helping to Improve Care
By Laura Freeman
James Cimino, MD
Information overload is one of the pervasive constants in modern life. That's especially true in health care. On the plus side, medical knowledge is expanding every day. The challenge is that finding what you need to know when you need it isn't always as simple as doing an internet search. So much is happening that you may not even know the answer exists out there in order to look for it.
Wouldn't it be great if information could make our work easier rather than us having to work so hard to keep up with it? That's what informatics is all about.
It's a game changer in many fields of endeavor. In health care, bioinformatics and its subspecialties--pharmaceutical informatics, nursing informatics, radiology informatics, clinical informatics, research informatics and more--are making it easier to ask the right question to get the right answer at the right time.
For students considering opportunities in health-related professions, there is a tremendous demand for people trained in informatics who also speak the language of health and biology.
What is informatics? It's more than IT.
"Informatics takes a broader view of the problem space to find general solutions that apply to specific tasks," James Cimino, MD, director of the UAB Informatics Institute, said. An internist, Cimino completed fellowships in informatics at Massachusetts General Hospital and Harvard before teaching at Columbia and creating the Biomedical Translational Research Information System at the NIH. He was just presented the 2019 Morris F. Collen Award of Excellence by the American College of Medical Informatics.
As an example of the broader view, Cimino explained how informatics would approach the task of creating a system of alerts and reminders to manage a medical condition.
"Instead of writing a program for each problem, informatics would create a knowledge base that would allow you to add more knowledge as you learn about other problems that might come up," he said. "You build a more general tool that is about representing underlying concepts and knowledge. When you want to ask a new question, you can do that. You don't have to create a new program each time."
It is important for an informaticist to know the meaning of what she is capturing so she can create a more useful tool with future flexibility built in.
"The nature of science and medicine is that when you ask a question and look for the answer, you find later that you have more questions," Cimino said. "If you create a tool that is too specific, it may not be able to look at the data you've gathered and answer those new questions. Informatics is more about building tools capable of answering questions you may not have anticipated yet--and without someone having to re-enter the same data from different sources.
"In clinical informatics, electronic medical records would take a more unified approach. If you want to model what's going on with a patient, you can get a clearer picture of overall health, how it's trending and what needs immediate attention. You create a knowledge base model of the patient. The patient has a blood pressure. The most recent reading is stored with historical data. Next time you have a new application that needs to know that reading, it knows where to look and can automatically retrieve it."
When patients visit their doctors with an acute problem, there may be very little time to go through records to look at the big picture of their health. New interfaces coming on the market have a simple, color-coded dashboard that shows physicians at a glance what health factors need attention and developing trends that need to be intercepted and redirected to help the patient achieve optimum health.
"There is a huge work force shortage of people who have both domain knowledge and training in informatics," Cimino said. "The opportunities in health care informatics can be compared to whether you want to design a car or drive it. For people who want to design the next big informatics tool and do research in informatics and artificial intelligence, the UAB Informatics Institute offers training. Our school of nursing has a track for nurses who want to design or use informatics tools in patient care.
"We're teaching pharmacy students how to use genomic biomarkers in working with physicians to choose the right dose of the medication that's most likely to be effective. Our students may also be involved in creating robotic pharmacy systems. Our medical and research students also learn about informatics tools and how to use them in patient care and science.
"When I design informatics tools for physicians and hospitals, understanding work flow and how to bring information into the work flow at the right point is a key consideration. We have to let physicians know the information is available and how to look for it, make the tool easy to use and the answers relevant to help them help their patients."
All of Us Looks to Improve Care for Each of Us
Powering the Future of Precision Medicine
Study Highlights Higher Death Rate for Young People Experiencing an Incident Episode of Psychosis
UAB Heads Two New National Rehab Research Centers
UAB's New Informatics Institute Applies Computers to Improve Care
American College of Medical Informatics, Bioinformatics, informatics, James Cimino MD, NIH, UAB Informatics Institute


For me, finding new and different ways to cook ribs mostly means finding a new sauce or glaze to use on the ribs themselves. Since I am limited to just the use of my oven, I don't have the options of a gas grill, charcoal grill or smoker at my disposal to use different methods to bring out different flavors. When I saw this recipe for Alton Brown's backyard baby back ribs, I knew I wanted to try it, but I didn't have the backyard methods to use like he does in the recipe. I also didn't have any baby back ribs on hand; I only had some St. Louis spareribs in the freezer. I really liked the sound of the rub and the marinade on the ribs however so I decided to adapt it for my purposes. I'll show you the original recipe here and then tell you what I did to change things around after.
Place each rib rack on a sheet of extra-wide, heavy-duty aluminum foil. (The foil should be 4 inches longer than the ribs on either end.) Season the rib racks liberally with kosher salt and sprinkle each rack with 3 tablespoons of the rub. Turn the ribs, meat side down, and tightly seal each foil pouch. Place on a half sheet pan and refrigerate the ribs overnight.
The next day, heat the oven to 250 degrees.
The fat in the braising liquid will have solidified on the top and can be removed at this time. Transfer the liquid to a small saucepan and add the honey, ketchup, Worcestershire sauce, espresso powder and cayenne pepper. Whisk the ingredients until they are well combined. Set the saucepan over medium-high heat and reduce the mixture to a glaze, about 10 minutes.
Set a gas grill to medium-high and allow it to heat for 10 minutes. Cut each slab of ribs in half and place them on the grill, flesh side down, close the lid and decrease the heat to medium. Leave everything alone for 3 minutes. Flip and cook the ribs for another 3 minutes. Flip and cook the ribs for 3 minutes on each side 1 more time or until each rib has a nice char. Remove the ribs from the grill to a cutting board. and cut the slabs into 2 rib portions, using kitchen shears. Add the ribs and half the glaze to a large serving bowl and toss the ribs to thoroughly coat them. Serve the remaining glaze on the side.
For the rub, place all of the ingredients in an airtight container and shake to combine. Store for up to 3 months.
Really the only change I made in the recipe comes in the final step. I heated the glaze in a small saucepan while I baked the ribs in a 375 degree oven for 25 minutes. I then glazed the ribs, turned the heat up to 400 and baked them for another 15 minutes before glazing them a final time and putting them under the broil for 2 or 3 minutes to get the char on them. Keep in mind I was using the St. Louis ribs, which are thicker and larger than baby back ribs, so they do take longer to cook through properly. It may not turn out the same as it would with a gas grill, but the ribs were still cooked well and tasted great. I really love the glaze and although I was skeptical with the use of the margarita mix in the whole thing, it did work quite nicely along with the orange juice, honey and the espresso powder. I would certainly give these ribs a try again. I apologize for the fuzzy picture; I didn't realize it had not turned out well and didn't take another one, but trust me, they are good!
This is a great recipe. I love Alton Brown, he has some great recipes and methods. Such a fun show to watch. Thanks for sharing.
I love his recipes too. He very often has great methods of making things and they come out perfectly. He's certainly one of my favorites. Thanks for the comment!
I make a simplified version that involves beer in the pouch – I didn't know alton used oj – might have to try that 🙂 my husband and I have "rib offs" and he cooks on charcoal and I cook mine in the oven then finish on broil or on the propane grill and they always win !
I like the idea of trying it with beer. I'll have to try it out and see how it does. Thanks for the comment and the idea Amber!


Three men who are alleged to have been involved in a robbery outside the ANZ Namaka branch appeared at the Nadi Magistrates Court today.
36-year-old Sunit Ram, 20-year-old, Anusheel Chand and 25-year-old Dveneel Ram are all charged with 1 count of aggravated robbery.
The incident happened over the weekend when a woman in her 60s who is employed by Yees Cold Storage was robbed outside the ANZ Bank Namaka branch.
More than $80,000 in cash and cheques which were stolen have also been recovered by Police.
The case has been transferred to the Lautoka High Court for the 6th of next month.
Bail was also denied for the three men.
Meanwhile, yesterday the driver of the vehicle Akshay Raju who is also allegedly involved in the robbery appeared in court.
He was also denied bail.


Housed in the mouth of this mythical creature is a blue orb that pops against the brushed metal and golden finish of this basilisk head. Speaking of heads, it has been contoured and detailed to not only look like basilisk but a handle for this stylish cane as well. Golden details accentuate the eyes, scales, and nose of this beast. Made from zinc aluminum this cane is not only striking but functional for that evening stroll you like so much. The shaft is constructed from stainless steel with a surprise inside. What's that? A stainless steel blade is hidden in the shaft for added protection from unsuspecting danger. Never be a lowly victim with this cane by your side. Provided at the bottom a rubber stopper is provided to prevent slipping. Sometimes if you wanna be a beast you just gotta embrace the beast.


BIRMINGHAM, Alabama -- Gov. Robert Bentley, in a show of continued resistance to the Affordable Care Act, said this afternoon that he will not set up a state health care exchange and he will not expand Medicaid under the federal healthcare overhaul.
"I will not set up a state exchange in Alabama," Bentley said during a speech to the Birmingham Business Alliance.
States have a Friday deadline to inform the U.S. Department of Health and Human Services if they plan to set up a state-run exchange, essentially a marketplace for people and businesses to shop for insurance. If states don't set up their own exchange, either alone or in federal partnership, then the federal government will step in and design it.
Bentley said he has been in communication with other governors -- including peers in Texas, Florida and Louisiana -- about the exchange decision. He expected multiple governors to show a united front of resistance to the Affordable Care Act.
"If we stand together, I do believe Congress is going to have to look at this again,"Bentley said.
Bentley said he expected other governors to announce similar decisions.
"That will send a clear signal to all of our elected leaders in Washington that the health care bill should be changed," Bentley said.
Bentley questioned the constitutionality of the the federal government stepping in and setting up essentially a state agency through a federally designed exchange. Oklahoma has filed a lawsuit alleging that it is unlawful for the federal government to establish an exchange within a state, Bentley noted.
"We believe the federally facilitated system they will try to set up, we believe that is unconstitutional," Bentley said.
Bentley said a state study commission had estimated previously that a state exchange would cost up to $50 million annually to operate. He said the state cannot afford that. The commission estimated that the cost to operate an exchange in 2015 would range between $34 million and $49.6 million.
The exchanges -- whether run by the state or the federal government -- are supposed to be in place by 2014.
Bentley said he will also refuse to expand Medicaid as it currently exists under the Affordable Care Act. The expansion would have been paid for almost entirely by the federal government, but Bentley questioned the long-term cost to both the state and nation.
"I will not expand Medicaid as it exists under the current structure because it is broken," Bentley said."We just can not afford it. The people of America can not afford it."
Bentley, who is a doctor, said his decision to resist the Affordable Care Act was based on a difference of philosophy, not politics.
"It is, in my opinion, truly the worst piece of legislation that has ever been passed in my lifetime," Bentley said of the ACA.
Senate Minority Leader, Roger Bedford, D-Russellville, criticized the governor's decision on both the exchange and Medicaid expansion.
"It's a total shame. It's a complete failure of leadership by the Republican supermajority. What this means is Washington will run Alabama's healthcare system not Alabama," Bedford said.
Bedford said the state should also grab an opportunity to expand Medicaid with the federal government picking up most of the tab.
"There are 350,000 people that could get preventive care rather then showing up in an emergency room," Bedford said.
Speaker of the House Mike Hubbard, R-Auburn, said he applauded Bentley's "principled stand against Obamacare." Hubbard said implementing the Affordable Care Act would bloat government and put Alabama on a path to "fiscal disaster."
"The governor is in discussions with roughly two dozen of his counterparts in other states to coalesce against Obamacare and push back against its mandates. It's my hope that this coalition can send a wake-up call to Washington and reverse the dangerous trend of liberal policies and directives that Obama and Congressional Democrats are pushing so hard to implement," Hubbard said.
An advocacy group for low-income families expressed disappointment in Bentley's decisions.
"We're disappointed that the governor would close these doors for now. We think Alabamians deserve as good a deal from healthcare reform as folks in other states are getting, " Jim Carnes, communications director for Arise Citizens' Policy Project.
In Alabama about 351,000 people, including 244,804 previously uninsured, would join Medicaid under an expansion, according to 2010 estimates from the Henry J. Kaiser Family Foundation.
The suggested expansion would open Medicaid to adults younger than 65 with an income of less than 133 percent of the federal poverty level, which would be $14,856 for individuals and $30,657 for a family of four. The federal government would pay 100 percent of the cost of services for new enrollees for the first three years, but that eventually would drop to 90 percent.
"This offers us the opportunity to get hundreds of thousands who have no healthcare into preventive care. These are working people. They work in industries we all utilize every day -- restaurants, construction," Carnes said.
Bentley said people had assumed that after the election, the ACA could not be stopped.
He said the two key portions of the law are the Medicaid expansion and the exchanges.
"If we have a large enough number of states who refuse to do it, it is going to be very difficult for them," Bentley said.


Please note that GCISD does not endorse or guarantee the results of the following websites, these are provided as tools for research and self-guidance. While some of them have paid services, we have only reviewed the free versions.
Texas' newest college and career research tool for students, parents, and educators. This resource is sponsored by the Texas Education Agency, the University of Texas, the Texas Workforce Commission, and the Texas Higher Education Coordinating Board.
Texas Reality Check is an online interactive tool that students can use to determine what careers best suit them and the lifestyle that they would like to achieve. It gives valuable information about careers, income, and education in Texas.
From there, you can explore the careers on your list of matches. You can learn about the outlook (new job opportunities expected) for jobs in that field, average pay, and the typical education needed.
When you complete the test, you will get scores for each of six work values clusters. These scores show how important each work value is to you. In addition to your cluster scores, you will be presented with a list of 739 occupations that are rank-ordered according to how well they match your personal work values. The more a job agrees with your work values, the more likely you are to be satisfied in that job.


text:
Santa Claus may be at serious health risk: UK experts
Although he sets a brilliant example of good behaviour and teaches the importance of giving rather than receiving, he could probably do more to encourage healthy lifestyles.
By: PTI | London | December 24, 2017 2:59:16 pm
(Representational photo)
Santa Claus is adored by youngsters the world over, but he could be setting a bad example when it comes to his physical health and mental well being, according to UK doctors.
Centuries of sherry-drinking, eating mince pies and working night shifts could be putting Santa Claus at serious health risk, according to the Royal College of General Practitioners (RCGPs) – a professional body for doctors in the UK.
With every house leaving carrots for his reindeers and mince pies and cookies for him, it is likely Santa's BMI is exceptionally high.
Obesity can lead to numerous health problems, such as hypertension, diabetes, fatty liver disease, and cancer, the RCGP said in a statement.
As a result of his waistline, unhealthy diet, and alcohol intake, it is also possible that Santa Claus has developed gout – a painful joint condition caused by the build-up of uric acid in the blood.
Santa Claus is known for his tight black boots to help him combat the snow, but with all his long haul travel they could be damaging his blood vessels – although the activity throughout his journey will help reduce his risk a little.
It is not known if Santa has a companion at home, so he could be at risk of feeling lonely, they added.
Loneliness and social isolation can be just as bad for his health and wellbeing as having a chronic condition.
He also experiences a lot of work stress, as well as sleep deprivation in the week leading upto Christmas.
"Santa Claus embodies what should be the happiest time of the year, and he is loved by children all over the world," said Helen Stokes-Lampard, Chair of the RCGPs.
"Although he sets a brilliant example of good behaviour and teaches the importance of giving rather than receiving, he could probably do more to encourage healthy lifestyles – something youngsters and adults alike can benefit from," said Stokes-Lampard.
"Santa is almost certainly living with multiple morbidities, which, if left untreated, can become increasingly distressing and debilitating," she said.
Having a tipple of sherry at every house around the world in one night is a serious case of binge-drinking, which we know is incredibly dangerous, according to the experts.
"We're concerned that over the years he is likely developed a significant addiction. If left untreated, this could lead to immune system dysfunction, cirrhosis of the liver, pancreatitis or brain damage, not to mention bad skin and strong body odour," they said.
"The human body can only process one unit of alcohol per hour, which means excessive consumption could make Santa drunk very quickly," Stokes-Lampard said.
"This not only increases the likelihood of him slipping in the snow or mixing up important presents, but could also lead to long-term issues affecting his mood and mental health," she said.
"In the meantime, I would recommend that Santa gives the sherry a miss this year – and maybe asks Rudolph if he can share his carrots," she added.
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text:
Q: How can I store and manipulate text input upon pressing enter? I am trying to store text input upon pressing enter which is not working for me. Not even an alert goes off when I press enter.
Here is my current simplified code:
const ToDo = () => {
  const saveValueFunction = (e: any) => {
    console.debug(e.keyCode)
    if (e.keyCode === 13) {
      AsyncStorage.setItem('any_key_here', e)
      alert('Data Saved')
    }
  }

  const [value, onChangeText] = React.useState('')
  return (
    <TextInput
      placeholder="Add a Task"
      placeholderTextColor="aqua"
      color="aqua"
      backgroundColor="#262626"
      style={styles.textInput}
      onChange={(e) => onChangeText(e.target.value)}
      value={value}
      onKeyDown={(e) => saveValueFunction(e)}
    />
  )
}

A: You can use onKeyPress which is called when any key is pressed. It is called with Native event which has key property which holds values like Enter, Backspace or the character typed by the user. So you can compare it with Enter to detect the Enter pressed by the user.
const [value, setValue] = React.useState('');
const handleKeyPress = e => {
  if (e.key === 'Enter') {
    AsyncStorage.setItem('any_key_here', value);
    setValue('');
    showAlert();
    alert(`Task saved: ${value}`);
  }
};

<TextInput
  value={value}
  onChangeText={text => setValue(text)}
  onKeyPress={e => handleKeyPress(e)}
  placeholder="Add a Task"
  placeholderTextColor="aqua"
  color="aqua"
  backgroundColor="pink"
  style={styles.textInput}
/>

Code Playground: Expo

A: const [inputData, setInputData] = useState('');
const [includeds, setIncludeds] = useState([]);

 const handleChange = (e: any) => {
    setInputData(e.target.value);
  };

const onKeyPressEvent = (e: any) => {
      if (e.key === 'Enter') {
        if (
          includeds &&
          includeds.length < MAX_INCLUDES &&
          (inputData && inputData.length !== 0)
        ) {
          e.persist();
          setIncludeds(arr => [...arr, inputData]);
          setInputData('');
        }
      }
    }

return(
         <input
          onChange={e => handleChange(e)}
          onKeyDown={e => onKeyPressEvent(e)}
        />
 )

You can basically do something like this.You should implement your case on top of this code.

A: Just use onSubmitEditing={} prop in text input and call the save function inside the curly brackets.