NASA astronaut Peggy Whitson floats in the Destiny laboratory of the International Space Station.
At this very moment, astronaut Peggy Whitson is living in outer space. Earlier this year, the biochemist grew and harvested cabbage aboard the International Space Station. Whitson, who sold chickens to pay for her private pilot's license, has now made her way beyond Earth's atmosphere three times and is the oldest woman to have done such a thing. Forty years ago, when Whitson was still a teenager, no American woman had yet been to space.
Right around this time of year in 1977, NASA was getting the word out: Astronauts Needed! Specifically, NASA wanted to expand the astronaut corps beyond its traditional cadre of white, male test pilots to include women and minorities. At the time, only one woman — the Soviet cosmonaut Valentina Tereshkova — had ever been to space, and it had been almost 14 years.
Sally Ride was finishing up her degree in astrophysics at Stanford University. According to Ride's biographer Lynn Sherr, the graduate student saw information about NASA's call in the campus newspaper. Ride read the requirements for mission specialist and figured she qualified. She submitted her application by the end of January 1977. By the deadline in June, 8,079 people had applied for the promise of space travel. This group of astronauts would be the first since the Apollo program and would fly the space shuttle, which, at the time, was not yet a space-worthy craft.
In January 1978, when current astronaut Whitson was finishing high school in Iowa, NASA announced its new astronaut group. Of the 35 selected, six were women: Sally Ride, Judith Resnik, Kathryn Sullivan, Anna Fisher, Rhea Seddon, and Shannon Lucid.
At a time when the press wondered what makeup she'd take and engineers wondered how many tampons she'd need, Ride became the first space-faring American woman on June 18, 1983. Aboard the space shuttle Challenger, Ride operated the robotic arm as she helped to deploy and retrieve satellites. She flew again aboard Challenger the following year. She remains the youngest American to have traveled to space, at 32 years old.
Even before the shuttle's first flight, Judith Resnik was chided by Tom Brokaw during an interview on Today. He asked Resnik whether her career as an astronaut intimidated men and interfered with her dating life, and he wondered whether NASA was addressing the possibility of romantic relationships in space. A seemingly dumbfounded but patient Resnik explained that the women in the astronaut class were treated the same as the men, that they all treated each other as professionals, and that the only major accommodation NASA made was adding the extra-small size to the line of pressurized spacesuits. While Brokaw's questions for the electrical engineer are off the mark, especially with the launch pad over his shoulder, three of the six women in the class of 1978 did marry fellow astronauts.
Resnik's first spaceflight, in 1984, was only the second by an American woman and also space shuttle Discovery's first foray toward the stars. One month after Resnik landed, oceanographer Kathryn Sullivan became the third American woman in space in October 1984 and the first to make a spacewalk. Ride was also part of that crew aboard Challenger, making it the first space voyage that included two women.
Sally Ride shown here floating in the Challenger flight deck.
Resnik's second mission included two women as well but ended in tragedy. She and schoolteacher Christa McAuliffe were aboard Challenger on a cold Florida morning in January 1986. Seventy-three seconds after liftoff, the space shuttle broke apart, and the crew perished. McAuliffe never made it to space.
Ride served on the commission that investigated the Challenger accident. In fact, she is the person who passed along a leaked report that got that commission looking closely at the shuttle booster's O-rings as the underlying mechanical cause of the catastrophe. Ride served again on the board that investigated the Columbia accident in 2003, after that shuttle broke apart over the Southwestern United States on its way to land in Florida. The day after that accident, she gave a speech to young girls at a science festival and, according to Sherr, turned "the preteen grief session into a rallying cry" for overcoming fear in the face of risk.
Though she died of pancreatic cancer in 2012, Ride's rallying cry lives on in Sally Ride Science, an organization at the University of California San Diego that promotes STEM — science, technology, engineering, math — education and publishes the Cool Careers in STEM book series. Tam O'Shaughnessy, Ride's partner of 27 years, heads up the project.
Aside from Ride and Resnick, the other four female astronauts in the class of 1978 continue to lead their now earthbound lives.
Sullivan was part of the mission in 1990 that deployed the Hubble Space Telescope, an instrument that has allowed us to see far into the universe. After she flew her last mission in 1992, Sullivan headed up the Center of Science and Industry (COSI) in Columbus, OH. More recently, she served as the National Oceanographic and Atmospheric Administration Administrator. Currently, she is on a 12-month fellowship at the National Air and Space Museum doing research for a book about the philosophy and practice of satellite servicing, a subject that she also knows well firsthand.
Anna Fisher took a break from space but is looking skyward again. In 1984, on her only spaceflight, Fisher became the first mother in space, leaving her 15-month-old daughter on this planet. Fisher, who had been an emergency-room physician, was assigned to that mission when pregnant and showed up for training three days after giving birth. She and the rest of the crew aboard Discovery deployed and released satellites, a common task for the space shuttle. After the Challenger accident put shuttle flights on hold in 1986 and after giving birth to another daughter, Fisher took a seven-year leave of absence from NASA to raise her family. She returned in 1996 and is now working on the Orion spacecraft designed for the trip to Mars. According to a recent interview, Fisher is convinced humans will get there. Though she admits, "It's just going take a while," she suggests that becoming a physician or a geologist is the way to prepare if you want to be selected in that future astronaut group.
When she was selected by NASA in 1978, Rhea Seddon, who stood 5' 2", was the smallest person to become an astronaut and struggled with ladders and spacesuits designed for more traditionally sized pilot types. When we met Seddon in 2010, she said that Columbia was her favorite orbiter because she saw its first and last launches and rode aboard that shuttle twice herself. Seddon's first mission, however, was aboard Discovery in April 1985, when she helped deploy satellites and showed students on Earth how simple children's toys worked in space. Before she got to space, she fell in love and married another member of that 1978 astronaut group, Hoot Gibson. They never flew to space together, but they've shared their lives here on Earth ever since.
In 1991, Seddon flew the first mission dedicated to biology and used her medical degree to study how the systems of the human body — using the bodies of her fellow crew members as test subjects — were affected by microgravity.
Biochemist Shannon Lucid flew the first of her five — that's right, five — space shuttle missions in 1985. She shares that women's record for most spaceflights with several others, and nine men have logged more launches and landings. In 1993, Seddon and Lucid flew a mission together and focused their efforts on understanding how humans adapt to space, research that is necessary if we are to forge further to Mars.
Lucid was also the only woman ever to serve aboard the Russian space station Mir, where she lived for 179 days in 1996. As a result, she received the Congressional Space Medal of Honor at the end of that year and held the record for the longest spaceflight by a woman until 2007, when Sunita Williams surpassed Lucid's mark. A former test pilot, Williams also holds the women's record for most spacewalks and most hours of extravehicular activity, but maybe not for long.
Dozens of American women have now soared to the not-too-distant heavens. Forty years after women first were taken seriously as potential astronauts, Whitson is the first woman to command the International Space Station for the second time, assuming command of Expedition 51 on April 9. Her first station command was back in 2007, after which she became the first woman to serve as chief of the astronaut office. But she stepped down from that management role to take the giant leap back to space. In January of this year, she tied Sunita Williams's record number of spacewalks for a woman and surpassed Williams's record for most time spent in space by a woman. She is extending that record every day right now. On April 24, because of a just-announced three-month extension of her time aboard the space station, Whitson will exceed the American record for time in space held by Jeff Williams, who beat Scott Kelly's record last year. Now, it's time for a woman to take the lead.
In 2018, Jeanette Epps is scheduled to become the first black woman on an expedition crew aboard the International Space Station. Three black women helped paved her road to space. After also serving in the Peace Corps, Mae Jemison was the first in 1992, aboard space shuttle Endeavour. After working at NASA's Jet Propulsion Laboratory in California, Stephanie Wilson became an astronaut and then flew three missions over four years. In 2007, she became the first black woman to board the space station. After working at Kennedy Space Center in other roles for several years, Joan Higginbotham flew one shuttle mission to the space station in 2006. She now heads up community relations for Lowe's.
To catch a glimpse of Whitson's sparkle this year and Epps's twinkle next year as the space station passes 200 miles above your head, check NASA's Spot the Station website.
Last February, NASA announced that it had received a record number of more than 18,300 applications for its next astronaut class, the most since 40 years ago when the agency first considered women for the job. Half of the most recent group of eight astronauts were women. Later this year, we'll find out how many women will be in the next class of 14 future spacefarers.
Anna Leahy and Douglas R. Dechow are the authors of Generation Space: A Love Story from Stillhouse Press. They have published in The Atlantic, Airplane Reading, Air & Space Magazine, Fifth Wednesday Journal, and Curator. Leahy is also the author of Aperture, a poetry collection just out from Shearsman Books. See more at Generation Space.


text:
Room 1123 LHOB- Longworth House Office Building 15 Independence Avenue, SE
Residence: Snow Hill, NC
Elected: 2022 Next Election: 2024
Spouse: Yuvonka Shawnte Batts DOB: 8/29/1971
Bertie / Durham / Edgecombe / Gates / Granville / Halifax / Hertford / Martin / Northampton / Pitt / Vance / Warren / Washington / Wilson
Congressman Don Davis was born and raised in Snow Hill, North Carolina. He has spent his life answering the call to serve -- as a veteran, educator, minister, and dedicated public servant.
As a young man, Congressman Davis worked in the tobacco fields and faithfully attended the same church where he currently ministers. He graduated in 1994 from the United States Air Force Academy and became a commissioned officer in the United States Air Force, where he actively served in uniform for eight years. As a First Lieutenant, Davis coordinated Air Force One and CODEL operations at Andrews Air Force Base and supported families of military members as a mortuary officer.
Congressman Davis returned to eastern North Carolina as an assistant professor of Aerospace Studies at East Carolina University Air Force ROTC Detachment 600, where he taught national security affairs, military history, and leadership courses. As an educator for over 20 years, Davis mentored thousands of students as they completed their studies.
As a veteran, Congressman Davis continued his commitment to public service by becoming the youngest Mayor of Snow Hill at age 29, where he served seven years. In 2008, Congressman Davis was elected to the North Carolina State Senate, serving six terms. In 2022, Congressman Davis was elected to the U.S. House of Representatives, representing 19 counties comprising the First Congressional District of North Carolina in eastern North Carolina. The Region 7 delegation unanimously elected him to serve as their representative and on the Steering & Policy Committee. Congressman Davis remains committed to working with his colleagues, regardless of party affiliation, to address the needs of his constituents in the First Congressional District.
Davis holds a bachelor's degree in social sciences from the U.S. Air Force Academy, a master's degree in administration from Central Michigan University, a master's degree in sociology with a concentration in regional development, and a doctoral degree in education from East Carolina University.
Congressman Davis lives in Greene County, NC. He is married to Yuvonka, and they have three sons--Ryan, Justin, and Kyler.

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: C# Expression tree that calls a generic method I have a generic method, with the following signature
 private static void ProcessItem<T>(int id) where T : BaseItem

And it gets called in the following way
ProcessItem<RedItem>(id: 2)
ProcessItem<BlueItem>(id: 7)

My issue is that I get the type of item on application start up via reflection as a Type object.
So now I am looking for a way that I can construct an expression tree that will result in a lambda that calls this method with the appropriate type.
So I can do something like lambda.Invoke(Type type, int id). And this will call something along the lines of id => ProcessItem<type>(id)
I found a similliar issue answered here: https://stackoverflow.com/a/2850366/5493420
However, the answer there shows how to instantiate a generic param of IEnumerable<> whereas I simply need to call my method, transforming the Type object into an actual <Type> parameter that my method can accept.
I am not exactly sure if this is even possible (converting a Type object into an actual type parameter), but would love to hear any suggestions on the topic.
PS: I am also willing to take a different approach (some reflection tricks maybe), as long as it doesn't affect performance by more than 10-20%

redpajama_set_name: RedPajamaStackExchange


During the season so far, a number of incidents have been drawn to the attention of the MRC relating to capsizes. These may have been through instability, or lack of skill, consideration or unnecessarily aggressive behaviour on part of other paddlers.
Rule 5 iv) All paddlers are required to render assistance to other competitors in distress. – this means checking that a paddler in the water is able to cope with the situation well enough to get out of the water.
Rule 5 ii) Competitors must be able to swim adequately in the waters on which the race is being held. It is hoped that team leaders ensure that their paddlers know how to manage their boats when a capsize does occur, being able to swim to a place where emptying and re-entry are possible.
Should a paddler accidentally cause a capsize, it is expected that an apology and offer of assistance will be made.
Race organisers are reminded that the race management system provides the facility for them to enter time penalties or allowances. Should a paddler delay their own race to render assistance, it would be appropriate to use this. Should evidence make it clear that a paddler has refused to assist or ignored a situation that may require assistance; organisers should take measured and appropriate action.
It is accepted that a young junior may not be able to offer greater assistance than a tow to the bank, or staying with the paddler while they swim, but it is expected that an adult paddler will be able to offer greater assistance particularly if the swimmer is a junior.
Race organisers are reminded that reference to Rule 5iv) must be included in their briefing.
It is in the interest of all paddlers that they learn to look after themselves and each other in race situations and it is also expected that team leaders ensure that this is the case.


text:
Lord Chadlington
Lord Chadlington is the founder and CEO of Huntsworth PLC, he also holds shares in the company, and has been a member of the House of Lords since 1996.
Healthcare Communications Association (HCA) is a non-profit organisation whose members are made up of pharmaceutical companies and communication agencies that work in the health sector. According to its website, it is run 'by its members for its members.' It adds: 'It is now a high profile and influential player in the healthcare arena. It has sufficient influence and credibility to shape opinion and lead debate.'
One such member of the lobbying organisation is a communications company called Huntsworth PLC, who run a group of companies involved in 'communications and lobbying.'
One arm of the group is Huntsworth Health, which operates in the U.S., Hong Kong, and Europe including here. Their website states how the company 'provides a full continuum of consulting and communications services to the healthcare and well-being industry.'
One of Lord Chadlington's employees is Fiona Bride whose role at Huntsworth is the 'director of market access.' Her area of work is succinctly laid out on her personal profile page on the Huntsworth website: Fiona says she has: 'expertise at leveraging commercial opportunities through market access at all levels of the NHS.'
In April 2010 Huntsworth Health's director Fiona Bride chaired a meeting of the HCA, which looked at the 'central role of commissioning in the NHS.' Interestingly, the meeting took place two months before Andrew Lansley had released the white paper (Liberating the NHS), which since developed into the much maligned Health and Social Care bill.
Three months after the HCA meeting and in the same month as the white paper was released, Huntsworth Health acquired healthcare communications agency, ScopeMedical for £4.6m, thus expanding its health division. Lord Chadlington said of the takeover: "We are delighted to announce the acquisition of ScopeMedical," then added: "Healthcare is a major growth area and we are now very well positioned to take advantage of that growth with a fully integrated healthcare offering that supports the product lifecycle from discovery to patent expiry." It is not just Lord Chadlington that thinks his company is in a good position. Liberal Democrat peer Lord Alliance has shares in the company. The coalition is even closer than we realised.
Incidentally, Lord Chadlington is the Prime Minister's constituency party chairman. They know each other well. Lord Chadlington paid £715,000 for a house next to Mr Cameron's last November; the home which Mr Cameron took out a £350,000 taxpayer-funded mortgage on. Lord Chadlington never moved in but sold David Cameron, a piece of the land at £137,000, which Cameron failed to declare.
The merry-go-round of politicians sitting in positions of power and working for corporations so that influence is increased is perhaps nothing new, but in the case of Huntsworth, they have truly had their fair share. Not only do they have Lord Chadlington as their CEO, but up until last year, they also had Lord Puttnam as a Director, and from 2001-03 Baroness Cumberlege was one of their non-executive directors. Francis Maude was a director of Huntsworth in 2005, following a merger with Incepta Group plc: Four Peers, One MP, One company. Not bad.
Further connections between the lobbying company and the Conservatives were revealed in an investigation by the Independent, which showed the company had given money to the party over several years. Lord Chadlington had until recently denied there had been any payments, however, Electoral Commission records exposed this as a lie. Huntsworth gave £15,500 to the party in August last year and has given money every year since 2008. Following the exposure, Huntsworth were forced to admit they had given money stating the money was given by buying tickets for 'Conservative events', a classic way for lobbying to take place. Furthermore, Lord Chadlington, and his wife have personally given £80,823.91 according to the electoral register, of which £44,700 went to the Central party - £21,623 went to David Cameron's office in Witney. A further £4,500 was given to Michael Howard's leadership campaign and £10,000 to Cameron's leadership campaign in 2010.
So, when Lord Chadlington (also known as Peter Gummer, the brother of John Gummer the former minister under John Major and fellow Lord) votes in the Lords, we know that anything he might say in the arguments for and against any amendments, will be clouded by the possibility of self-interest. Alongside this we need to consider to, the forty other Lords with financial interests and the prospect of the possible financial benefits the bill will present to their respective interests.
So there we have it. Four Lords working for one company who receive work from the NHS and through their membership of the Healthcare Communications Association act in tandem with pharmaceutical companies lobbying the government.
There are 141 Lords with private healthcare financial interests. For more on whether they are breaking the Rules of conduct and to see what the Lords have said in reply to Social Investigations, please click here.
Labels: 'Democracy', 'Huntsworth Health', 'Huntsworth PLC', 'Lord Chadlington', 'NHS'
Meet Lord Chadlington: He's about to vote on the H...
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text:
Media Tours Aliso Canyon – Site of Gas Leak That Displaced Thousands Of Nearby Residents
[NOTE: Aliso Canyon shows us that oil and gas infrastructure can fail and have real health impacts for the surrounding communities. While this leak was related to a storage issue, it still underscores the importance of having strong protections in place to make sure that we're using the best practices and technology to keep our communities safe. Pennsylvania can't wait any longer to develop the strong protections that would prevent an infrastructure failure like this.
Want to get involved and push Pennsylvania to adopt strong public health protections for oil and gas operations? Let us know by filling out this form.
- CleanAirPa.org]
CBS Los Angeles
ALISO CANYON (CBSLA.com) — For the first time since the massive methane gas leak was finally capped nearly a year ago, the media was allowed to tour the Aliso Canyon Storage Facility near Porter Ranch.
The 2015 four-month natural gas leak, which scientists called the largest in U.S. history, displaced at least 7,000 Porter Ranch residents for months because the toxic fumes were making them sick.
Ken Harris is the State Oil & Gas Supervisor and head of the Department of Conservation's (DOC) Division of Oil, Gas, and Geothermal Resources.
"I appreciate how difficult it has been for them. I understand their concerns. We are trying to ensure that the facility or any facility in California never has an upset like this again. That's our goal," Harris said.
CBS2's Randy Paige got a look at what Harris said was redundant safety systems – from multiple layers of pipes to sophisticated pressure monitors at each well.
There were infrared cameras that can detect tiny amounts of methane gas and infrared instruments that keep watch along the borders of the facility.
Harris said 34 of the 114 wells there had passed rigorous safety inspections, and the natural gas storage facility will remain empty and off line until each of the wells either passes inspection is temporarily sealed and placed off line or plugged and abandoned altogether.
"When we're done, this will be a safe facility," Harris said.
In a few months after a decision is made about the fate of each of the wells, a public meeting will be held to allow people who live near the plant to share their thoughts.
Then state regulators will be asked to decide whether or not to allow methane gas back into the massive underground reservoir.
http://losangeles.cbslocal.com/2017/01/12/media-tours-aliso-canyon-site-of-gas-leak-that-displaced-thousands-of-nearby-residents/


text:
10 Tips "IT" Factor
mixtape News
LIL WAYNE CELEBRATES #1 WITH THA CARTER V
October 10, 2018 October 10, 2018 rgarcia	LIL WAYNE CELEBRATES #1 WITH THA CARTER V
LONG ANTICIPATED ALBUM
CARTER V
DEBUTS #1 ON BILLBOARD 200 CHART
RAPPER'S FOURTH #1 ALBUM
2ND LARGEST U.S. STREAMING ALBUM OF THE YEAR (433M STREAMS)
APPLE MUSIC'S 2ND LARGEST STREAMING DAY FOR AN ALBUM
HONORED WITH BET "I AM HIP HOP" AWARD AT
BET HIP HOP AWARDS IN MIAMI, FL
PERFORMING TONIGHT ON NFL'S MONDAY NIGHT FOOTBALL
GENESIS HALFTIME SHOW
BETWEEN WASHINGTON RED SKINS & NEW ORLEANS SAINTS
WATCH LIL WAYNE PERFORM "DEDICATE"
ON THE TONIGHT SHOW WITH JIMMY FALLON
"At his best, he is an electric storyteller, with verses that vibrate fiercely on the word level while assembling into something epic…" — New York Times
October 8, 2018 — New York, NY — Grammy Award winning rap artist Lil Wayne'scelebrates another #1 album with his recently released Tha Carter V (Young Money/Republic Records). It topped the charts as #1 album in both the Rap and Hip Hop/R&B categories streaming over 433 Million times in its debut week. The much anticipated project — which according to Nielsen has clocked in at over 480,000 in sales — hosts over 23 tracks and is Wayne's fourth #1 album after Tha Carter IV (2011), I Am Not a Human Being (2010) and the landmark Tha Carter III (2008). Tha Carter V holds rank as the third largest streaming album of the year (following Post Malone's Beerbongs & Bentleys and Drake's Scorpion) and contributed to Apple Music's 2nd largest streaming day for an album. Featuring the likes of Kendrick Lamar, Snoop Dogg, Nicki Minaj, Travis Scott and the late XXXTentacion, Wayne's Tha Carter V — which has already received critical acclaim — continues to solidify the rapper's aptly monikered title of being the "Greatest of All Time." Listen to Tha Carter VHERE, and for the full tracklist, see below.
The album release came at the heels of Lil Wayne's 36th birthday last week and was the first stop of a week long run of celebration for the artist. Wayne stopped by "The Late Night Show with Jimmy Fallon" for a little couch time and performed "Dedicate" off the project — WATCH HERE. Wayne then returned to his home turf in New Orleans for "CRWN with Elliot Wilson" for a round of discussions around the making of the album. The momentus week was capped this past weekend where Lil Wayne was honored with the "I AM HIP HOP"award at the BET Hip Hop Awards which took place in Lil Wayne's second home of Miami, FL.
Having sold millions of albums worldwide and garnered five GRAMMY awards (most recently for the track "No Problem" by Chance The Rapper ft. Lil Wayne & 2 Chainz), Lil Wayne is one of the most successful and critically lauded artists in Hip Hop. Touted Rap's first rock star, he released his first project at the age of 12 and went on to release his first solo album in 1999 when he was just 17. He released his first installment of his legendary Tha Carter series in 2004 before releasing three others, including the landmark Tha Carter III in 2008. Lil Wayne also holds the record for the most entries on the Billboard Hot 100 chart by a male solo artist with 138 entries including 20 Top 10 Hits (3rd most appearance all-time). His most recent studio album and the much anticipated, Tha Carter V, was released at the end of September and debuted at #1 on the Billboard 200 Charts — continuing his streak with four #1 albums inclusively. Lil Wayne, aptly monickered the "Greatest of All Time" is also one of only three rappers to have sold over a million albums in the first week including 10 million RIAA Certified Albums and 21 million RIAA Certified Digital Singles. Lil Wayne is also a celebrated author who released his memoir "Gone Till November" in October of 2016 chronicling his experience in Rikers Island. Outside of his iconic music career, Lil Wayne has continued on as the CEO of his own Young Money Records (in conjunction with Republic Records) and was recently awarded the "I Am Hip Hop" award at this year's BET Hip Hop Awards.
THA CARTER V TRACKLIST:
I Love You Dwayne
Don't Cry ft. XXXTentacion
Let It Fly ft. Travis Scott
Can't Be Broken
Dark Side of The Moon ft. Nicki Minaj
Mona Lisa ft. Kendrick Lamar
What About Me ft. Sosamann
Famous ft. Reginae Carter
Dope Niggaz ft. Snoop Dogg
Hittas
Took His Time
Open Safe
Start This Shit Off Right ft. Ashanti & Mack Maine
Dope New Gospel ft. Nivea
Let It All Work Out
For more information on Lil Wayne, please contact:
Chris Chambers & Kasturi (Kaz) Shan
The Chamber Group — 212.366.5801
chris@thechambergroup.com / kasturi@thechambergroup.com
← Diggy Simmons Ask For You To Text Him In His Latest Single
Young Trap's new single "Too Much Sauce." →
(240)425-2193 or (240)593-7519
DJ Platform
OMB PEEZY, YFN LUCCI, & YUNGEEN ACE LINK UP FOR NEW SINGLE "HUSTLE" 💸
December 19, 2020 December 23, 2020 rgarcia
ALABAMA'S FINEST OMB PEEZY RELEASES NEW SINGLE "HUSTLE" FEATURING YFN LUCCI & YUNGEEN ACE ** LISTEN HERE** [NEW YORK, NY – DECEMBER 18,
DJ Platform Rap
PUBLIC ENEMY Team Up with Beastie Boys' Ad Rock & Mike D and Run DMC for "Public Enemy Number Won" — Watch Now!
October 30, 2020 rgarcia
DJ Platform Event
Live Rap Battles Are Here! Start Your Own Battle!
October 24, 2020 October 24, 2020 rgarcia
Indie Top 20
Public Enemy Release Official Video for "GRID" ft Cypress Hill and George Clinton
SHAWN MENDES SOARS TO HIS 4TH CONSECUTIVE #1 ALBUM ON THE BILLBOARD TOP 200 WITH WONDER
NEXT2RISE HENNESSY CYPHER TOUR WILL BE IN ATLANTA ON DECEMBER 26TH AND 27TH AND WE NEED RAPPERS AND SINGERS
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Schümperli, Daniel
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Barman-Aksözen, Jasmin; Ćwiek, Paulina; Bansode, Vijay B.; Koentgen, Frank; Trüb, Judith; Pelczar, Pawel; Cinelli, Paolo; Schneider-Yin, Xiaoye; Schümperli, Daniel; Minder, Elisabeth I. (2017). Modeling the ferrochelatase c.315-48C modifier mutation for erythropoietic protoporphyria (EPP) in mice. Disease models & mechanisms, 10(3), pp. 225-233. Company of Biologists Ltd. 10.1242/dmm.027755
Li, Meiling; Lightfoot, Helen Louise; Halloy, Francois; Malinowska, Anna; Berk, Christian; Behera, Alok; Schümperli, Daniel; Hall, Jonathan (2017). Synthesis and cellular activity of stereochemically-pure 2'-O-(2-methoxyethyl)-phosphorothioate oligonucleotides. Chemical communications, 53(3), pp. 541-544. Royal Society of Chemistry 10.1039/C6CC08473G
Odermatt, Philipp; Trüb, Judith; Furrer, Lavinia; Fricker, Roger; Marti, Andreas; Schümperli, Daniel (2016). Somatic therapy of a mouse SMA model with a U7 snRNA gene correcting SMN2 splicing. Molecular therapy, 24(10), pp. 1797-1805. Nature Publishing Group 10.1038/mt.2016.152
Schümperli, Daniel (2016). Rudolf Weber (1922-2015): a driving force in the transition of developmental biology into a molecular and cellular science. Development genes and evolution, 226(2), pp. 65-67. Springer 10.1007/s00427-016-0532-9
Romeo, Valentina; Schümperli, Daniel (2016). Cycling in the nucleus: regulation of RNA 3' processing and nuclear organization of replication-dependent histone genes. Current opinion in cell biology, 40, pp. 23-31. Elsevier 10.1016/j.ceb.2016.01.015
Neve, Anuja Vilas; Trüb, Judith; Saxena, Smita; Schümperli, Daniel (2016). Central and peripheral defects in motor units of the diaphragm of spinal muscular atrophy mice. Molecular and cellular neuroscience, 70, pp. 30-41. Elsevier 10.1016/j.mcn.2015.11.007
Duque, Sandra I; Arnold, W David; Odermatt, Philipp; Li, Xiaohui; Porensky, Paul N; Schmelzer, Leah; Meyer, Kathrin; Kolb, Stephen J; Schümperli, Daniel; Kaspar, Brian K; Burghes, Arthur H M (2015). A large animal model of spinal muscular atrophy and correction of phenotype. Annals of neurology, 77(3), pp. 399-414. Wiley-Blackwell 10.1002/ana.24332
Raczynska, Katarzyna Dorota; Ruepp, Marc-David; Brzek, Aleksandra; Reber, Stefan; Romeo, Valentina; Rindlisbacher, Barbara; Heller, Manfred; Szweykowska-Kulinska, Zofia; Jarmolowski, Artur; Schümperli, Daniel (2015). FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors. Nucleic acids research, 43(20), pp. 9711-9728. Oxford University Press 10.1093/nar/gkv794
Romeo, Valentina; Griesbach, Esther; Schümperli, Daniel (2014). CstF64: cell cycle regulation and functional role in 3' end processing of replication-dependent histone mRNAs. Molecular and cellular biology, 34(23), pp. 4272-4284. American Society for Microbiology 10.1128/MCB.00791-14
Voigt, Tilman; Neve, Anuja Vilas; Schümperli, Daniel (2014). The craniosacral progression of muscle development influences the emergence of neuromuscular junction alterations in a severe murine model for spinal muscular atrophy. Neuropathology and Applied Neurobiology, 40(4), pp. 416-434. Wiley 10.1111/nan.12064
Huo, Qing; Kayikci, Melis; Odermatt, Philipp; Meyer, Kathrin; Michels, Olivia; Saxena, Smita; Ule, Jernej; Schümperli, Daniel (2014). Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins. RNA biology, 11(11), pp. 1430-1446. Landes Bioscience 10.1080/15476286.2014.996494
Ruepp, Marc-David; Schweingruber, Christoph; Kleinschmidt, Nicole; Schümperli, Daniel (2011). Interactions of CstF-64, CstF-77, and symplekin: Implications on localisation and function. Molecular biology of the cell, 22(1), pp. 91-104. Bethesda, Md.: American Society for Cell Biology 10.1091/mbc.E10-06-0543
Ruepp, Marc-David; Schümperli, Daniel; Barabino, Silvia M.L. (2011). mRNA 3' end processing and more - multiple functions of mammalian cleavage factor I-68. RNA - a publication of the RNA Society, 2(1), pp. 79-91. Woodbury, N.Y.: Cold Spring Harbor Laboratory Press 10.1002/wrna.35
Voigt, Tilman; Meyer, Kathrin; Baum, Oliver; Schümperli, Daniel (2010). Ultrastructural changes in diaphragm neuromuscular junctions in a severe mouse model for Spinal Muscular Atrophy and their prevention by bifunctional U7 snRNA correcting SMN2 splicing. Neuromuscular disorders, 20(11), pp. 744-52. Amsterdam: Elsevier 10.1016/j.nmd.2010.06.010
Matulis, Gediminas; Sanderson, Joseph P; Lissin, Nikolai M; Asparuhova, Maria B; Bommineni, Gopal R; Schümperli, Daniel; Schmidt, Richard R; Villiger, Peter M; Jakobsen, Bent K; Gadola, Stephan D (2010). Innate-like control of human iNKT cell autoreactivity via the hypervariable CDR3beta loop. PLoS biology, 8(6), e1000402. Lawrence, Kans.: Public Library of Science 10.1371/journal.pbio.1000402
Ruepp, Marc-David; Vivarelli, Silvia; Pillai, Ramesh S.; Kleinschmidt, Nicole; Azzouz, Teldja N.; Barabino, Silvia M.L.; Schümperli, Daniel (2010). The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 30-end processing of animal histone mRNAs. Nucleic acids research, 38(21), pp. 7637-7650. London: Oxford University Press 10.1093/nar/gkq613
Ittig, Damian; Luisier, Samuel; Weiler, Jan; Schümperli, Daniel; Leumann, Christian J. (2010). Improving gene silencing of siRNAs via tricyclo-DNA modification. Artificial DNA, PNA & XNA, 1(1), pp. 9-16. Austin, Tex.: Landes Bioscience 10.4161/adna.1.1.11385
Nlend, Rachel Nlend; Meyer, Kathrin; Schümperli, Daniel (2010). Repair of pre-mRNA splicing: Prospects for a therapy for Spinal Muscular Atrophy. RNA biology, 7(4), pp. 730-740. Georgetown, Tex.: Landes Bioscience 10.4161/rna.7.4.12206
Barta, Andrea; Schümperli, Daniel (2010). Editorial on Alternative Splicing and Disease. RNA - a publication of the RNA Society, 7(4), pp. 388-389. Woodbury, N.Y.: Cold Spring Harbor Laboratory Press 10.4161/rna.7.4.12818
Meyer, Kathrin; Marquis, Julien; Trüb, Judith; Nlend Nlend, Rachel; Verp, Sonia; Ruepp, Marc-David; Imboden, Hans; Barde, Isabelle; Trono, Didier; Schümperli, Daniel (2009). Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation. Human molecular genetics, 18(3), pp. 546-555. Oxford: Oxford University Press 10.1093/hmg/ddn382
Marquis, J.; Kampfer, S.S.; Angehrn, L.; Schümperli, Daniel (2009). Doxycycline-controlled splicing modulation by regulated antisense U7 snRNA expression cassettes. Gene therapy, 16(1), pp. 70-7. London: Nature Publishing Group 10.1038/gt.2008.138
Ruepp, Marc-David; Aringhieri, Chiara; Vivarelli, Silvia; Cardinale, Stefano; Paro, Simona; Schümperli, Daniel; Barabino, Silvia M.L. (2009). Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export. Molecular biology of the cell, 20(24), pp. 5211-23. Bethesda, Md.: American Society for Cell Biology 10.1091/mbc.E09-05-0389
Asparuhova, Maria B.; Barde, Isabelle; Trono, Didier; Schranz, Karin; Schümperli, Daniel (2008). Development and characterization of a triple combination gene therapy vector inhibiting HIV-1 multiplication. Journal of gene medicine, 10(10), pp. 1059-1070. Chichester: Wiley 10.1002/jgm.1238
Marquis, Julien; Meyer, Kathrin; Angehrn, Larissa; Kämpfer, Sacha; Rothen-Rutishauser, Barbara; Schümperli, Daniel (2007). Spinal muscular atrophy: SMN2 pre-mRNA splicing corrected by a U7 snRNA derivative carrying a splicing enhancer sequence. Molecular therapy, 15(8), pp. 1479-1486. New York, N.Y.: Nature Publishing Group 10.1038/sj.mt.6300200
Asparuhova, Maria; Marti, Gabriela; Liu, Songkai; Serhan, Fatima; Trono, Didier; Schümperli, Daniel (2007). Inhibition of HIV-1 multiplication by a modified U7 snRNA inducing Tat and Rev exon skipping. Journal of gene medicine, 9(5), pp. 323-334. Chichester: Wiley 10.1002/jgm.1027
Scholl, Raphael; Marquis, Julien; Meyer, Kathrin; Schümperli, Daniel (2007). Spinal Muscular Atrophy: position and functional importance of the branch site preceding SMN exon 7. RNA biology, 4(1), pp. 34-37. Georgetown, Tex.: Landes Bioscience 10.4161/rna.4.1.4534
Azzouz, Teldja N.; Pillai, Ramesh S.; Däpp, Christoph; Chari, Ashwin; Meister, Gunter; Kambach, Christian; Fischer, Utz; Schümperli, Daniel (2005). Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes. Journal of biological chemistry, 280(41), pp. 34435-34440. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M505077200
Xu, Hongzhi; Pillai, Ramesh S.; Azzouz, Teldja N.; Shpargel, Karl B.; Kambach, Christian; Hebert, Michael D.; Schümperli, Daniel; Matera, A. Gregory (2005). The C-terminal domain of coilin interacts with Sm proteins and U snRNPs. Chromosoma, 114(3), pp. 155-166. Springer 10.1007/s00412-005-0003-y
Gorgoni, Barbara; Andrews, Stuart; Schaller, André; Schümperli, Daniel; Gray, Nicola K; Müller, Berndt (2005). The stem-loop binding protein stimulates histone translation at an early step in the initiation pathway. RNA - a publication of the RNA Society, 11(7), pp. 1030-1042. Woodbury, N.Y.: Cold Spring Harbor Laboratory Press 10.1261/rna.7281305
Azzouz, Teldja N.; Gruber, Andreas; Schümperli, Daniel (2005). U7 snRNP-specific Lsm11 protein: dual binding contacts with the 100 kDa zinc finger processing factor (ZFP100) and a ZFP100-independent function in histone RNA 3' end processing. Nucleic acids research, 33(7), pp. 2106-2117. Oxford University Press 10.1093/nar/gki516
Ittig, D.; Liu, Shi-Xia; Renneberg, Dorte; Schümperli, Daniel; Leumann, Christian (2004). Nuclear antisense effects in cyclophilin A pre-mRNA splicing by oligonucleotides: A comparison of tricyclo-DNA with LNA. Nucleic acids research, 32(1), pp. 346-353. Oxford University Press 10.1093/nar/gkh187
Liu, Songkai; Asparuhova, Maria; Brondani, Vincent; Ziekau, Ingrid; Klimkait, Thomas; Schümperli, Daniel (2004). Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin A. Nucleic acids research, 32(12), pp. 3752-3759. Oxford University Press 10.1093/nar/gkh715
Schümperli, Daniel; Pillai, R S (2004). The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein. Cellular and molecular life sciences, 61(19-20), pp. 2560-2570. Birkhäuser-Verlag; www.birkhauser.ch 10.1007/s00018-004-4190-0
Asparuhova, Maria B.; Kole, Ryszard; Schümperli, Daniel (2004). Antisense derivatives of U7 and other small nuclear RNAs as tools to modify pre-mRNA splicing patterns. Gene Therapy and Regulation, 2(4), pp. 321-349. VSP International Science Publishers 10.1163/1568558043967472
Azzouz, Teldja N; Schümperli, Daniel (2003). Evolutionary conservation of the U7 small nuclear ribonucleoprotein in Drosophila melanogaster. RNA - a publication of the RNA Society, 9(12), pp. 1532-1541. Cold Spring Harbor Laboratory Press 10.1261/rna.5143303
Pillai, Ramesh S; Grimmler, Matthias; Meister, Gunter; Will, Cindy L; Lührmann, Reinhard; Fischer, Utz; Schümperli, Daniel (2003). Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes & development, 17(18), pp. 2321-2333. Cold Spring Harbor Laboratory Press 10.1101/gad.274403
Brun, C; Suter, D; Pauli, C; Dunant, P; Lochmüller, H; Burgunder, J M; Schümperli, Daniel; Weis, J (2003). U7 snRNAs induce correction of mutated dystrophin pre-mRNA by exon skipping. Cellular and molecular life sciences, 60(3), pp. 557-566. Springer
Pettitt, Jonathan; Crombie, Catriona; Schümperli, Daniel; Müller, Berndt (2002). The Caenorhabditis elegans histone hairpin-binding protein is required for core histone gene expression and is essential for embryonic and postembryonic cell division. Journal of cell science, 115(Pt 4), pp. 857-866. Company of Biologists Limited
Zanier, Katia; Luyten, Ingrid; Crombie, Catriona; Muller, Berndt; Schümperli, Daniel; Linge, Jens P; Nilges, Michael; Sattler, Michael (2002). Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression. RNA - a publication of the RNA Society, 8(1), pp. 29-46. Cold Spring Harbor Laboratory Press
Renneberg, Dorte; Bouliong, Emilie; Reber, Ulrich; Schümperli, Daniel; Leumann, Christian J. (2002). Antisense properties of tricyclo-DNA. Nucleic acids research, 30(13), pp. 2751-2757. Oxford University Press 10.1093/nar/gkf412
Pillai, R S; Will, C L; Lührmann, R; Schümperli, Daniel; Müller, B (2001). Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein. EMBO journal, 20(19), pp. 5470-5479. Nature Publishing Group 10.1093/emboj/20.19.5470
Michel, F; Schümperli, Daniel; Müller, B (2000). Specificities of Caenorhabditis elegans and human hairpin binding proteins for the first nucleotide in the histone mRNA hairpin loop. RNA - a publication of the RNA Society, 6(11), pp. 1539-1550. Cold Spring Harbor Laboratory Press
Martin, F; Michel, F; Zenklusen, D; Müller, B; Schümperli, Daniel (2000). Positive and negative mutant selection in the human histone hairpin-binding protein using the yeast three-hybrid system. Nucleic acids research, 28(7), pp. 1594-1603. Oxford University Press 10.1093/nar/28.7.1594
Suter, Daniel; Tomasini, Reto; Reber, Ueli; Gorman, Linda; Kole, Ryszard; Schümperli, Daniel (1999). Double-target antisense U7 snRNAs promote efficient skipping of an aberrant exon in three human β-thalassemic mutations. Human molecular genetics, 8(13), pp. 2415-2423. Oxford University Press 10.1093/hmg/8.13.2415
Sierakowska, H; Sambade, M J; Schümperli, Daniel; Kole, R (1999). Sensitivity of splice sites to antisense oligonucleotides in vivo. RNA - a publication of the RNA Society, 5(3), pp. 369-377. Cold Spring Harbor Laboratory Press
Walther, T N; Wittop Koning, T H; Schümperli, Daniel; Müller, B (1998). A 5'-3' exonuclease activity involved in forming the 3' products of histone pre-mRNA processing in vitro. RNA - a publication of the RNA Society, 4(9), pp. 1034-1046. Cold Spring Harbor Laboratory Press
Gorman, L; Suter, D; Emerick, V; Schümperli, Daniel; Kole, R (1998). Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 95(9), pp. 4929-4934. National Academy of Sciences NAS
Furger, A; Schaller, A; Schümperli, Daniel (1998). Functional importance of conserved nucleotides at the histone RNA 3' processing site. RNA - a publication of the RNA Society, 4(3), pp. 246-256. Cold Spring Harbor Laboratory Press
Müller, B; Schümperli, Daniel (1997). The U7 snRNP and the hairpin binding protein: Key players in histone mRNA metabolism. Seminars in cell & developmental biology, 8(6), pp. 567-576. Elsevier 10.1006/scdb.1997.0182
Wyler-Duda, P; Bernard, V; Stadler, M; Suter, D; Schümperli, Daniel (1997). Histone H4 mRNA from the nematode Ascaris lumbricoides is cis-spliced and polyadenylated. Biochimica et biophysica acta (BBA) - gene structure and expression, 1350(3), pp. 259-261. Elsevier 10.1016/S0167-4781(96)00235-7
Martin, F; Schaller, A; Eglite, S; Schümperli, Daniel; Müller, B (1997). The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein. EMBO journal, 16(4), pp. 769-778. Nature Publishing Group 10.1093/emboj/16.4.769
Gruber, Andreas; Stettler, P; Heiniger, P; Schümperli, Daniel; Lanzrein, B (1996). Polydnavirus DNA of the braconid wasp Chelonus inanitus is integrated in the wasp's genome and excised only in later pupal and adult stages of the female. Journal of general virology, 77(11), pp. 2873-2879. Society for General Microbiology 10.1099/0022-1317-77-11-2873
Turner, P C; Whalen, A; Schümperli, Daniel; Matera, A G (1996). The bona fide mouse U7 snRNA gene maps to a different chromosome than two U7 pseudogenes. Genomics, 31(2), pp. 250-252. Elsevier 10.1006/geno.1996.0042
Stefanovic, B; Wittop Koning, T H; Schümperli, Daniel (1995). A synthetic histone pre-mRNA-U7 small nuclear RNA chimera undergoing cis cleavage in the cytoplasm of Xenopus oocytes. Nucleic acids research, 23(16), pp. 3152-3160. Information Retrieval Ltd.
Stefanovic, B; Hackl, W; Lührmann, R; Schümperli, Daniel (1995). Assembly, nuclear import and function of U7 snRNPs studied by microinjection of synthetic U7 RNA into Xenopus oocytes. Nucleic acids research, 23(16), pp. 3141-3151. Information Retrieval Ltd.
Albrecht, U; Wyler, T; Pfister-Wilhelm, R; Gruber, Andreas; Stettler, P; Heiniger, P; Kurt, E; Schümperli, Daniel; Lanzrein, B (1994). Polydnavirus of the parasitic wasp Chelonus inanitus (Braconidae): characterization, genome organization and time point of replication. Journal of general virology, 75(12), pp. 3353-3363. Society for General Microbiology 10.1099/0022-1317-75-12-3353
Spycher, C; Streit, A; Stefanovic, B; Albrecht, D; Koning, T H; Schümperli, Daniel (1994). 3' end processing of mouse histone pre-mRNA: evidence for additional base-pairing between U7 snRNA and pre-mRNA. Nucleic acids research, 22(20), pp. 4023-4030. Information Retrieval Ltd.
Wittop Koning, T H; Schümperli, Daniel (1994). RNAs and ribonucleoproteins in recognition and catalysis. European journal of biochemistry, 219(1-2), pp. 25-42. Blackwell Science 10.1111/j.1432-1033.1994.tb19911.x
Streit, A; Koning, T W; Soldati, D; Melin, L; Schümperli, Daniel (1993). Variable effects of the conserved RNA hairpin element upon 3' end processing of histone pre-mRNA in vitro. Nucleic acids research, 21(7), pp. 1569-1575. Information Retrieval Ltd.
Grimm, C; Stefanovic, B; Schümperli, Daniel (1993). The low abundance of U7 snRNA is partly determined by its Sm binding site. The EMBO Journal, 12(3), pp. 1229-1238. EMBO Press
Mital, R; Albrecht, U; Schümperli, Daniel (1993). Detection of UV-induced RNA:protein crosslinks in snRNPs by oligonucleotides complementary to the snRNA. Nucleic acids research, 21(4), pp. 1049-1050. Information Retrieval Ltd.
Melin, L; Soldati, D; Mital, R; Streit, A; Schümperli, Daniel (1992). Biochemical demonstration of complex formation of histone pre-mRNA with U7 small nuclear ribonucleoprotein and hairpin binding factors. The EMBO Journal, 11(2), pp. 691-697. EMBO Press
Harris, M E; Böhni, R; Schneiderman, M H; Ramamurthy, L; Schümperli, Daniel; Marzluff, W F (1991). Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps. Molecular and cellular biology, 11(5), pp. 2416-2424. American Society for Microbiology
Gruber, Andreas; Soldati, D; Burri, M; Schümperli, Daniel (1991). Isolation of an active gene and of two pseudogenes for mouse U7 small nuclear RNA. Biochimica et biophysica acta (BBA) - gene structure and expression, 1088(1), pp. 151-154. Elsevier 10.1016/0167-4781(91)90167-K
Gruber, Andreas; Streit, A; Reist, M; Benninger, P; Böhni, R; Schümperli, Daniel (1990). Structure of a mouse histone-encoding gene cluster. Gene, 95(2), pp. 303-304. Elsevier
Soldati, D; Schümperli, Daniel (1990). Structures of four human pseudogenes for U7 small nuclear RNA. Gene, 95(2), pp. 305-306. Elsevier
Meier, V S; Böhni, R; Schümperli, Daniel (1989). Nucleotide sequence of two mouse histone H4 genes. Nucleic acids research, 17(2), p. 795. Information Retrieval Ltd.
Meyer, K.; Schümperli, Daniel (2012). Antisense Derivatives of U7 Small Nuclear RNA as Modulators of Pre-mRNA Splicing. In: Stamm, Stefan; Smith, Christopher W. J.; Lührmann, Reinhard (eds.) Alternative pre-mRNA Splicing: Theory and Protocols (pp. 481-494). Chichester: John Wiley & Sons 10.1002/9783527636778.ch45
Nlend Nlend, R.; Schümperli, Daniel (2012). Antisense Genes to Induce Exon Inclusion. In: Aartsma-Rus, Annemieke (ed.) Exon Skipping : Methods and Protocols. Methods in Molecular Biology: Vol. 867 (pp. 325-347). Heidelberg: Springer 10.1007/978-1-61779-767-5_21
Schümperli, Daniel (2012). Beeinflusst die moderne Bio- und Gentechnologie die Evolution? In: Dubach, Martina (ed.) Evolution wohin? Die Folgen der darwinschen Theorie (pp. 201-213). Zürich: vdf Hochschulverlag
Schümperli, Daniel (2012). Eigenschaften gentechnisch veränderter Pflanzen. In: , (ed.) Nutzen und Risiken der Freisetzung gentechnisch veränderter Pflanzen. Chancen nutzen, Risiken vermeiden, Kompetenzen erhalten. Programmsynthese NFP 59 (pp. 74-95). Zürich: vdf Hochschulverlag
Schümperli, Daniel (2002). Megatrends in medicine. In: Leuthold, M.; Leuenberger, H.; Weibel, E.R. (eds.) Megatrends – rise and fall of megatrends in science. Basel: Schwabe
Stauber, C; Soldati, D; Lüscher, B; Schümperli, Daniel (1990). Histone-specific RNA 3' processing in nuclear extracts from mammalian cells. In: RNA Processing Part B: Specific Methods. Methods in enzymology: Vol. 181 (pp. 74-89). San Diego, CA: Academic Press
Duque, S.; Porensky, P.; William, D.A.; Odermatt, Philipp; Nlend, Rachel; Bevan, A.K.; Foust, K.; Braun, L.; Schmelzer, L.; Schümperli, Daniel; Kaspar, B.K.; Burghes, A.H.M. (2013). O.8 Intrathecal delivery of AAV9 vectors to model and rescue a large animal model of SMA. Neuromuscular disorders, 23(9-10), p. 797. Elsevier 10.1016/j.nmd.2013.06.558
Burghes, A.; McGovern, V.; Porensky, P.; Duque, S.; Bevan, A.; Foust, K.; Odermatt, P.; Nlend, R.; Massoni-Laporte, A.; Mitrpant, C.; Wilton, S.; Schümperli, Daniel; Kaspar, B. (October 2012). Spinal muscular atrophy SMA: SMNs spatial requirement and therapies. Neuromuscular disorders, 22(9-10), pp. 907-908. Amsterdam: Elsevier 10.1016/j.nmd.2012.06.342
Ruepp, Marc-David; Schweingruber, Christoph; Kleinschmidt, Nicole; Schümperli, Daniel (2010). Interactions of symplekin, CstF-64, and CstF-77. Implications for localisation, stability and function. In: The Fifteenth Annual Meeting of the RNA Society Seattle, Washington USA, June 22-26, 2010 (p. 1). RNA Society
Ittig, Damian; Schümperli, Daniel; Leumann, Christian J. (2008). Tc-DNA modified siRNA. Nucleic Acids Symposium Series, 52(1), pp. 501-502. Oxford University Press 10.1093/nass/nrn254
Schümperli, Daniel; Albrecht, U; Koning, T W; Melin, L; Soldati, D; Stauber, C; Lührmann, R (1990). Biochemical studies of U7 snRNPs and of histone RNA 3' processing. Molecular Biology Reports, 14(2-3), pp. 205-206. Kluwer Academic Publishers


text:
Iraq's Kurdish region halts oil exports
Published December 26th, 2012 - 12:14 GMT
Iraq's semi-autonomous Kurdish region has halted oil exports due to a row over payments
An Iraqi Kurdish official said on Tuesday that the country's self-ruled northern Kurdish region has suspended oil exports over a payment row with Baghdad, a development that could add to already souring relations between the Kurds and the Arab-led central government.
Since the 2003 US-led invasion, the Kurds have unilaterally struck more than 50 deals with foreign oil companies, even though Baghdad says they have no right to do so. In 2011, the two sides reached a tentative deal by which the Kurds send the oil to Baghdad, which sells it, and pays 50 per cent of the revenues to the developers to reimburse the development costs.
In April, the Kurds halted exports of around 100,000 barrels a day, saying that Baghdad had made only two payments under the agreement and had failed to pay $1.5 billion they say they were owed.
Four months later, the Kurds agreed to restart exports as a goodwill gesture. That allowed the two sides to reach a new agreement under which Baghdad would pay one trillion Iraqi dinars (about $848 million) to the companies in September.
However, Ali Hussein Balo, the advisor of the Kurdish Ministry of Natural Resources, said Baghdad sent only 650 billion Iraqi dinars (about $550 million) and withheld the rest. That prompted the Kurds' latest move.
Separately, Iraq and neighbouring Jordan have agreed to speed efforts to build a pipeline to export Iraqi oil through the Jordanian Red Sea port of Aqaba, according to Jordan's Petra news agency.
The deal calls for an oil pipeline that would have a capacity to export one million barrels a day, Petra reported.
Tags:BaghdadPetraKurdish Ministry of Natural ResourcesAli Hussein Balo
Via SyndiGate.info
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I was fussing and fuming. Things weren't going my way. I was even having stress dreams. Frustrated, I was ready to declare myself a loser. With a capital L.
But then I sat back and thought about it. I don't have control over this thing. There isn't a single concrete action I could take to make things better. All I could is be patient.
And then I thought some more. On many other things, things in which I have control, I was doing quite well. In my work productivity, in athletics and exercise, in my diet, in my commitment to read inspirational and classic literature, and in my commitment to journal regularly.
The goals I set were being achieved. Better than I thought they would, in fact.
Things will never be perfect. But if you set goals, no matter how small, you can know that you are moving in the right direction.
And if you constantly move in the right direction, you will inevitably put yourself on the path to success.


text:
India – the last frontier for the fanatics ….
February 25, 2020 February 25, 2020 by Bindu & Krishnan
In the days after the CAA was passed by the parliament, there are three pictures that sent a chill down my spine and they tell a disturbing story of our country at this present juncture. I am no political commentator nor an activist – I am just a regular citizen of India with a deepening sense of dread.
I welcome the CAA and I feel it should have been implemented much earlier. I am unable to find a single reason for the Muslim citizens of India to feel threatened by the CAA because it has nothing to do with any citizen of India. Secondly, as far as the NRC is concerned, it is an imperative that India knows who its citizens are ! The argument being furthered by the Shaheen Bagh protestors and the "woke" non-intellectuals about how this Modi Govt will use CAA+NRC to throw out Muslims from India is unbelievable and flawed. India is not a "dharamshala" or a caravanserai for anyone to land up here illegally, enjoy all the benefits as a citizen and then claim the place as their own.
The 3, 4, or 5 crore Bangladeshis who are here illegally have to leave – we have no obligation towards them. The Rohingyas who have come all the way from Myanmar to Kashmir and then to Kerala need to go back to Myanmar or Bangladesh. Again, we have no obligation towards them. The way the CAA+NRC combo offer is being twisted is to say that the illegal Hindus/Buddhists/Christians/Jews will get to stay on in India using the CAA's religious persecution clause while the Muslims will be thrown out. For a minute, lets further that argument and see the end result – who are being persecuted in our neighbouring Islamic countries ? Pakistan, Bangladesh and Afghanistan are Islamic countries who happen to be our neighbours. Are Muslims being persecuted in these countries ? So why should India let illegal Muslim immigrants to remain in India ? Where is our obligation towards them ?
We do have an obligation towards the Hindus – there is no country where a persecuted Hindu can go to except India and even here, he/she needs to show his papers and wait for 5 years before getting citizenship. It isn't automatic and India doesn't go looking for persecuted Hindus everywhere and rescue them at enormous cost like Israel does for the Jews. Many times I feel jealous of the jews and feel like converting to Judaism because there is a country that loves me so much just for being a Jew !!
The albatross of "Secularism" is heavy around India's neck …. and it is beginning to choke. The Hindu temples are controlled by the government while Christian and Muslim institutions are managed by their own trusts/leaders. If CONgress had continued ruling this country, it would have succeeded in proving that Hindus are terrorists and fulfilled the colonial dream ! At 15% of the population – India has the second largest number of Muslims (200 million) in the world living here. Is that because of persecution ??? How warped is that argument. I haven't heard of a single Indian Muslim leaving India because he/she is persecuted. I would like to see data of how many Muslim citizens have fled India because the government has treated them badly or they have been harassed…. can't find it anywhere. I don't want any Indian citizen to leave India but that's what these pseudo-seculars, and woke "non-intellectuals" will have us believe about our Muslim citizens.
The first disturbing picture –
The Charlie Hebdo cartoonists were killed along with a few of their colleagues (12 in all) ….. and all of literate India put the French flag on their FB profiles and wrote "je suis Charlie" (I am Charlie) in support of those killed. The cartoonists said something terrible about Prophet Mohammed on their magazine cover. I offer this information with no comment except to ask, when those who said something terrible about an individual born 1400 years ago and were shot dead, what should a billion people feel about the poster in the picture above where "OM", the sound of the universe and a sacred symbol of utmost respect in Hinduism has been desecrated ???? Did any Hindu even feel outraged about whoever created this sinister poster and which country posted India's flag on its FB profile ?
Hinduism traces itself back to atleast 5000 years, even going by the "western" historical timeline and if History is granted "freedom of expression", based on facts, its probably 17000 to 20000 years old, if not older. Are Hindu symbols not sacred then ?
The second picture –
I don't know if this is a doctored picture and if it is, someone should have pointed it out on Twitter and elsewhere. Haven't seen anyone saying that this is fake for nearly a month and a half so am assuming it is not fake.
First a sacred symbol of Hindus is desecrated and then the country's flag is …. Why this hatred towards a country that has given you everything ? Every Indian Muslim and Christian has Hindu forefathers – whether they would like to accept it or not. None of them came from anywhere else. So why the hatred towards Hindus? Why the hatred for India ?
The third picture –
This is the most recent one .. probably a day old. And this is what the other two pictures were building upto. India cannot/should not/hopefully will not become an Islamic state or a Christian country. India is the only country where people are truly free to pursue whatever religion they choose to and it is because of our Hindu heritage. The day we have citizens pointing a gun at a police officer we have become an anarchy. Those who want India to fail will succeed. This is what happened in Syria, Lebanon, Egypt and every other country – citizens breaking the law and civil war leading to mass exodus. It would help to remember, that Hindus have no other country in the world …
Neither Islam nor Christianity offer equivalence nor acceptance to any other religion and India is caught in the middle with its billion strong Hindu population ….. a bunch of people whose way of life (not religion) doesn't teach them to hate someone who prays to a different God. As a Hindu, I can choose a stone or a human being or a ISRO satellite as my God… but a Christian or a Muslim cannot. The problem arises when you want me NOT to choose the ISRO satellite as my God – who the F$2k are you to decide on my behalf? As an Indian, I can make the above statement and still expect to live, but the day this country becomes an Islamic state, I will be reborn after being killed … and if this country becomes a Christian nation, I will forget my freedom to choose my God.
India thus is the last frontier for the fanatics and the last oasis for religious freedom…. deeply disturbed and truly worried that the fanatics may gain ground because again, the truly educated, non-partisan, free thinking Indians don't care enough to raise their voice.
Jai Hind.
p.s – Mr. Waris Pathan getting away with his recent rant "15 Cr Muslims Will Be Tough On 100 Cr Hindus" says a lot :(:(.
Categories Disturbed Ramblings, Political Ponderings Tags CAA, Christian, citizens, government, Hindu, illegal immigrants, India, Muslim, NRC Post navigation
Why 90 Rolls Royces ?


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McLean favoured in her final Nova Scotia junior golf championship
Glenn MacDonald (gmacdonald@herald.ca) The Chronicle Herald
Published: Jul 08, 2019 at 8:18 p.m.
Updated: Jul 16, 2019 at 10:33 a.m.
Heather McLean of Wagner College watches her drive during the Brown Bear Invitational, an NCAA Division 1 golf tournament in October. McLean will defend her Nova Scotia junior girls' championship this week in Truro. - Wagner Athletics
From the Annapolis Valley to the bright lights of the Big Apple, Heather McLean had a ball during her freshman NCAA Division 1 season at Wagner College.
The 2018 Nova Scotia women's amateur and junior girls' champion was the youngest player on the Seahawks' golf team. But the unflappable McLean played like a crafty veteran. She began her collegiate career with a pair of top 10 finishes, concluded it with a tie for fourth at the 54-hole, Northeast Conference (NEC) championship and earned second-team all-conference honours for the year.
But accolades aside, her fondest memory of her first year at the Staten Island university was experiencing all that The City That Never Sleeps had to offer.
"Being in New York is so cool; I really like it there," McLean, a biology major, said in a recent interview.
"The college is so near to everything. It seems like almost every weekend, when we weren't in season, I tried to get over into the city just to get my mind off school and golf and have some fun. I love being in the city."
Her TLC for NYC was certainly enhanced by playing some of her best golf at 18 years old.
"I was really proud of how I played," said Ken-Wo's McLean. "I got to play in every single tournament we had and tied for tops on the team at the conference championship. I was happy with that.
"My coach at Wagner helped me a lot with my short game. That part of my game got a whole lot better," she added. "I really liked the whole team aspect of college golf, too. There definitely was an adjustment going from playing as an individual to playing as a team. But I liked it. We came third in our conference, which tied the school's best finish ever. That was great for us.
"It really makes me excited for next year."
Before she returns to Wagner at the end of August, she has a summer chock full of provincial and national tournaments.
McLean started her season with a tie for fourth at the Future Links Quebec championship last month.
She, again, tied for fourth at the recent Nova Scotia women's amateur championship at Greenwood.
Although she didn't successfully defend her amateur title — Chester's Allison Chandler won by two strokes over McLean's sister Meghan — she heads into this week's Nova Scotia junior championship at Truro as the reigning champion.
When she won last year's junior event by 12 strokes at Northumberland Links, McLean became just the third golfer to win both the women's amateur and junior girls' championships in the same year.
Rita Lohnes did it three times (1955, 1957, 1959) while fellow Ken-Wo member Laura Harris pulled off the feat twice (2004, 2007).
McLean would like nothing better than another provincial title in her junior swan song.
"It's pretty crazy that this is my last year in junior," McLean said. "I feel like I've done this for my whole life. It's the end of a chapter. So I definitely want to go out and have my best season and hopefully do really good at juniors.
"Knowing how well I played at a collegiate level definitely gives me a lot of confidence. I'm a lot more confident over the ball and I feel like I have a lot more knowledge of the game."
And she has plenty of course knowledge of Truro Golf Club to fall back on. The challenging 5,778-yard, par-71 track was the site of her '18 amateur victory.
"I love Truro," McLean said. "When I think about Truro I have happy memories. I'm probably biased because I won the amateur there. But I'm definitely excited to play the juniors there."
A new junior boys' winner will be crowned this year with the graduation from the junior ranks of three-time defending champ Shaun Margeson.
Chester's Mark Chandler, who was runner-up to Margeson by two strokes last year at Northumberland Links, is one of the favourites in the boys' division. His older brother Matthew won the event in 2015.
"My game held up last year and I was really happy with the result," Chandler said of his runner-up finish in 2018. "I hope I get to play some really good golf at Truro."
Chandler is coming off a tie for 17th at the recent Nova Scotia men's amateur at Abercrombie.
Other junior girls' players to watch are Ashburn's Haley Baker, who last week successfully defend her New Brunswick junior championship title, and Ken-Wo's Sara Cumby. On the boys' side, contenders include Ashburn's Jake Smith, Kieran Allain and Ewan Kelly Jr., Andrew Cash of The Lakes Golf Club and Truro's Owen Mullen.
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BE IT REMEMBERED, that the White County Commissioners held a regular meeting on Monday, August 18, 2014. The meeting was held at the White County Building, 2nd floor Commissioners' Conference Room, beginning at 8:00 a.m.
White County Clerk Paula Lantz said that one of the polling locations that was used last year experienced difficulties with parking. She requested permission to move precincts Union 3 and Union 7 from White Oak Health Campus to the Monticello Christian Church Fellowship Hall, in Monticello.
Commissioner Diener asked if the new location meets the ADA standards. Clerk Lantz said that she has done an ADA study on all of the locations and they are all ADA compliant.
Clerk Lantz and John Million also presented a resolution authorizing the Election Board to adopt a plan for Vote Centers.
NOW, THEREFORE, BE IT RESOLVED AND CERTIFIED BY THE WHITE COUNTY BOARD OF COMMISSIONERS THAT THE White County Election Board is authorized, pursuant to Indiana 3-11-18.1-3 to proceed with the drafting, adoption, and implementation of a Vote Center Plan, along with the administration of Vote Centers for White County, starting with the November General Election for 2014.
Auditor Rogers presented an ordinance for first reading that limits the amount of comp time that can be accrued by all county employees county wide. The ordinance proposes that when an employee reaches the maximum amount of comp time; overtime will be paid out. This is to eliminate employees receiving large income checks after they retire.
Auditor Rogers said that she contacted other county Auditors to see what their policies were to help her put the ordinance together.
Section 1: Compensatory "Comp" time may be accrued in lieu of being paid overtime for all non-exempt employees as outlined in the Fair Labor Standards Act of 1938, as Amended, Sec. 207(m)(2)(B)(o) (Section 207(k) for calculation for employees working in public safety) on an hour-for-hour basis for additional hours worked up to forty (40) hours per week or at a rate of one and one-half times the amount of approved hours worked in excess of forty (40) in a normal work week up to a total not to exceed two (2) of the employee's regular work weeks.
Section 2: The calculation of compensatory time is based on actual hours worked. Time of on sick leave, vacation leave, personal leave, compensatory time or any other leave of absence will not be considered as hours worked for purposes of calculating compensatory time. Holiday hours will be considered as ours worked for purposes of calculating overtime hours. Use of compensatory time must be determined in advance of submission of the payroll.
Section 3: An employee absent for a qualifying event under the Family and Medical Leave Act shall utilize the following banked benefit leave; 1) sick leave; 2) compensatory time; and 3) vacation time. The employee shall be paid for these benefit hours as part of the employee's FMLA leave time.
Section 4: Comp time will be reported on the employee's service record to the White County Auditor with each payroll claim voucher.
Section 5: Effective immediately, all full-time employees working in a benefit position may accrue a maximum of two (2) of the employee's regular work weeks compensatory time before monetary compensation is paid, unless an increase in the maximum compensatory time hours is approved by the Board of Commissioners.
Section 6: Elected Officials and Department Heads are required to monitor the accrual of compensatory time. All compensatory time shall be approved in advance of accrual or use. In order to avoid excessive financial liability, Elected Officials and Department Heads must limit their department's maximum allowance of banked compensatory hours to exceed neither the maximum allowed by ordinance nor the balance of their annual overtime budget appropriation. Elected Officials and Department Heads are encouraged to schedule use of compensatory time as soon as possible to avoid accrual beyond the stated limit that would require monetary payment.
Section 7: The Human Resources Department shall provide a compensatory time off agreement to advise non-exempt employees of the County's compensatory time off policy.
Section 8: Upon termination of employment, employees are entitled to payment of the unused balance of their accrued compensatory time. Payment for accrued and unused compensatory time at termination may be included in the employee's last regular earnings paycheck, if possible, or in a separate check.
Section 9: Upon adoption, this ordinance will be incorporated as an amendment to any department Personnel Policy currently in effect.
The second reading will be held at the next Commissioners' meeting on September 2, 2014.
Area Plan Director Joe Rogers asked permission to change the permitting process for parking lots. Currently, the requirement is that anytime a business owner wants to re-stripe their parking lot, they are required to get a permit. This is done to verify that the parking lot is ADA compliant. Now, Director Rogers would like to issue a parking lot permit that will be valid for 3 years. If the owner would like to re-stripe the parking lot the following year, a renewal will be issued. This will eliminate the owner from having to apply for a new permit, pay another fee and submitting another site plan.
Economic Development President Randy Mitchell presented his Business Summary August 2014 report.
Mr. Mitchell met with five existing business owners in the county to talk about business retention and expansion. Two new businesses started up in the county: Elite Auto and Marine, Monticello; and Reclaimed Hope, in Brookston.
On the calendar, Mr. Mitchell will be meeting with five site selectors and three Economic Development representatives in Indianapolis to present the Mid American Commerce Park and the Monticello Professional Park. He will also be joining the Mayor of Monticello in hosting a delegation from China. They are interested in learning more about our arts, sports and music in our schools. Twin Lakes will be putting on a nice demonstration for them.
Nine students will be graduating from the second Advanced Manufacturing class. Students will have the opportunity to participate in an interview fair on August 26.
Area Plan Director Joe Rogers submitted a copy of his Building Permit report for July. Forty-four permits were issued last month; three of them were for new homes.
Mr. Rogers did conduct a GIS training session where he had twenty-one attendees.
Jim Reynolds, Environmental Officer, presented a copy of his environmental report for August.
Received 44 calls/complaints on various issues.
County work crew mowed 3 properties.


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Miramar's giant wheel was the only attraction I managed to visit at Neihu, which is a shame because there are actually a lot of tourist spots to visit in this district! The National Palace Museum, for one, is just nearby. Go there and you also get to enjoy the other famous neighboring attractions like the park for aborigines and another museum named Shung Ye. But it was raining that day. I know. Excuses. I hate umbrellas and raincoats and I've grown tired of museums. I love history in its written form through books. Artifacts and clothes from another century don't amuse me that much. Well, they actually did when I visited that museum at Lotte World but that was my first out of the country excursion, and so everything was fascinating. As you get to visit more places they start to become the same.
The fee for the giant wheel ride is NT$200 on a weekend and NT$150 on a weekday. There are also tandem tickets for sale for the National Palace Museum. The ride itself does not last 30 minutes but you would see a good view of the city even before reaching the top. Taipei 101 is visible, far but recognizable. And then you have green hills and mountains on the other direction.
One thing I've noticed is that I am still afraid of heights. The Macau Tower Bungy jump didn't really eliminate my acrophobia. I think it even worsened it. I found it hard to look down from above so I just tried to enjoy the view without looking at the streets below. The twenty minutes or so that I spent there felt like an eternity. What I suggest is that you also just enjoy the view or perhaps, close your eyes and rest. It is the perfect opportunity for a breather before or after shopping.
The mall itself is okay. There is something for everyone. You can shop, bring the kids to Tom's World, or watch a movie in the biggest IMAX cinema in the island. WeGo hotel is just next door, and as mentioned, the other popular tourist spots of Taipei are just within the vicinity. Aside from the reasons already stated, I also don't know how to ride a bus. How do you know the fares? The stops? If you have that card that locals have then it would be easier for you. Buses have censors by the entrance and the required fee is automatically deducted from that card, saving you from the hassles of communicating with the driver or not having coins for the fare.


Update 04/04/19: Goal achieved, thanks to donations coming from our network. If you still want to donate, feel free to contribute with our work through the main donation page.
Update 04/03/2019: Thanks to generous donors, we reached our goal of $500. Help us raise $1,000 by Friday.
Our partners in Pine Ridge need our help: The South Dakota reservation has been hit hard by the severe flooding that has plagued much of the midwest for the past two weeks. Many roads are impassable. Homes have been damaged, and residents have been stranded since the flooding began. Access to food and clean drinking water is increasingly limited.
The Oglala Lakota Nation has declared a state of emergency on the Pine Ridge Reservation in South Dakota. A blizzard followed by rapid snowmelt caused fast-rising waters on the reservation, jeopardizing nearby dams and overflowing creeks and rivers. The fallout from severe flooding has made many roads impassable and trapped some residents in their homes for over two weeks. Many reservation towns have been without water since a main water line washed out from flooding. Some stranded residents are relying on supplies being delivered on horseback.
Please help us show our friends in Pine Ridge some love from the Amizade network! Our goal is to raise $1,000 by Friday. All money raised through this campaign will go towards the purchase of bottled water and the costs of road and home repairs for local residents with flood damage.


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Bengals practicing as several NFL teams sit out; A.J. Green and Joe Burrow speak out
"It's just starting from the top, having the uncomfortable conversation with the owners, the general managers, and making everyone feel comfortable."
By Jason Marcum@marcum89 Aug 27, 2020, 2:37pm EDT
Share All sharing options for: Bengals practicing as several NFL teams sit out; A.J. Green and Joe Burrow speak out
Mark Konezny-USA TODAY Sports
The Cincinnati Bengals are holding practice today as training camp will wrap up soon. However, they'll be doing so amid protests around sports that have seen teams boycotting practice and even games.
On Wednesday, the Milwaukee Bucks boycotted Game 5 of their first-round /NBA playoff series against the Orlando Magic. After that, the Houston Rockets vs. Oklahoma City Thunder and Portland Trail Blazers vs. Los Angeles Lakers games were also postponed.
The boycotts were to protest racial injustice in America, specifically a Black man named Jacob Blake being shot seven times in the back by police in Kenosha, Wisconsin on Sunday.
Now, NFL teams are taking part, as the Arizona Cardinals, New York Jets, Indianapolis Colts, Tennessee Titans Green Bay Packers are among the clubs who have canceled their Thursday practices.
The Bengals are practicing today, but several players did speak out prior to practice, specifically A.J. Green.
"I don't have a problem with it," Green told Bengals.com of deciding to practice today. "But at the same time, I think we as a team need to get together and have a bigger discussion (about) what's going on in this world, how we can make a change and I think it starts from the top."
Green then mentioned that the changes pro athletes are demanding to see starts at the top.
"It's just starting from the top, having the uncomfortable conversation with the owners, the general managers, and making everyone feel comfortable," Green said. "I think a lot of players are scared to talk because a lot of people aren't financially stable to where they can make comments on how they feel about things and not feel like they will get cut or something like that. I think it starts from the top and that will create an environment where these guys are comfortable voicing their opinion and not feel like, 'This could cost me my job because I have a family to feed.'"
Bengals quarterback Joe Burrow posted this on Twitter:
How can you hear the pain Black people are going through and dismiss it as nothing. How can you hear the pain and respond with anything other than "I stand with you."
— Joey Burrow (@JoeyB) August 27, 2020
It's great to see the Bengals' leaders stepping up and saying what needs to be said to help bring attention to the injustices being done in America. Hopefully, their voices are heard and make a valuable impact on society.
Bengals training camp 2020: Everything to know
Zac Taylor on A.J. Green's return: 'One of the best receivers in the NFL'
Bengals practicing as several NFL teams sit out; Green & Burrow speak out
Joe Mixon battling migraines


Analog Devices, Inc., which recently acquired Linear Technology Corporation, announces the LTC2358-18, an 18-bit, 8-channel simultaneous sampling successive approximation register (SAR) ADC featuring integrated picoamp input buffers. With board real estate at a premium, the LTC2358-18 brings substantial space and cost savings by eliminating front end signal conditioning circuitry normally required driving unbuffered switched-capacitor ADC inputs. The combined component savings of three amplifiers, six resistors and two capacitors for each channel, a total of 88 components over 8 channels, saves BOM cost and significant board space and provides over 40% savings in power consumption. Picoamp inputs and 128dB CMRR over a 30VP-P common mode range enable the LTC2358-18 to directly connect to a wide range of sensors without compromising measurement accuracy.
While converting eight channels at 200ksps per channel throughput, the LTC2358-18 provides added flexibility via independently configurable SoftSpan input ranges. Each channel can be programmed on a conversion-by-conversion basis to accept ±10.24V, 0V to 10.24V, ±5.12V, or 0V to 5.12V unipolar, true bipolar, fully differential or arbitrary input signals. The differential analog inputs operate over a wide 30V input common mode range, allowing the ADC to directly digitize a variety of signals while simplifying the signal chain design. The input signal flexibility, combined with unrivaled ±3.5LSB maximum INL, no missing codes at 18 bits, and 96.4dB SNR, makes the LTC2358-18 ideal for high performance industrial process control, test and measurement, power line monitoring and motor control applications.
The LTC2358-18 features a precision internal reference with 20ppm/°C maximum temperature coefficient and an integrated reference buffer capable of accurate one-shot measurements, providing space savings in densely packed circuit boards. Optionally, an external 5V reference can be used to expand the analog input range to ±12.5V. The device dissipates 219mW when converting eight channels simultaneously at 200ksps per channel, and features nap and power-down modes to reduce power dissipation at slower throughputs.
In addition to its unique analog characteristics, the LTC2358-18 offers unmatched digital flexibility, featuring pin-selectable SPI CMOS and LVDS serial interfaces. The wide digital output supply range allows the device to communicate with any CMOS logic between 1.8V and 5V. In CMOS mode, applications can employ between one and eight lanes of serial output data, enabling the user to optimize bus width and data throughput. LVDS mode offers low noise, high speed communications over greater distances using differential signaling. Together, these I/O interface options enable the LTC2358-18 to communicate equally well with legacy microcontrollers and modern FPGAs.
The LTC2358-18 follows the LTC2358-16, leading a family of multichannel 18-/16-bit simultaneous sampling buffered SAR ADCs. Specified over the −40°C to 125°C temperature range, the LTC2358-18 is offered in a 48-lead 7mm x 7mm LQFP package that is pin-compatible with the unbuffered LTC2348-18. 1,000-piece pricing starts at $25.95 each. Device samples and evaluation circuit boards are available online or from your local Linear Technology sales office. For more information, visit www.linear.com/product/LTC2358-18.