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Articles tagged "IgG"
Clazakizumab (CLZ, Anti-IL-6 Monoclonal Antibody) Treatment of Patients (Pts) with Chronic Antibody-Mediated Rejection (cABMR) Reduces Total Immunoglobulin (Ig) and Anti-HLA IgG Antibody Levels
B. Shin, N. F. Ammerman, A. A. Vo, X. Zhang, S. C. Jordan, M. Toyoda
Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: We have recently reported successful use of Tocilizumab (TCZ), an anti-IL-6 receptor (R) monoclonal antibody, for cABMR treatment in HLA-sensitized kidney transplant (KTx) Pts.…
Individualized Preconditioning for ABO-Incompatible Living Donor Kidney Transplantation: An Initial Report of 48 Cases from China
X. -. Wang
Department of Urology/Institute of Urology, West China Hospital of Sichuan University, Chengdu, China
*Purpose: Typically, the majority of centres that perform ABO incompatible (ABOi) kidney transplantation use fixed preconditioning protocols regardless of the initial titer. As experience in…
Liver Transplantation in Children with Type 1 and Type 2 Autoimmune Hepatitis
I. G. Roepe, J. A. Goss, T. Miloh
Department of Student Affairs, Baylor College of Medicine, Houston, TX
*Purpose: Autoimmune Hepatitis (AIH) can be defined as type 1 and type 2 based on autoantibodies. Liver transplant (LT) may be indicated for chronic liver…
QA of MMR/VZV Protocol-Driven Serologic Screening and Infectious Disease Consultation (IDC) Are Strongly Recommended in Heart, Lung, Liver (HLL) SOTs
Z. Seckin, L. Brumble, C. Libertin
Mayo Clinic, Jacksonville, FL
*Purpose: SOT recipients are at risk of acquiring life-threatening infections putting their graft and life at risk. Prevention, including immunization with live virus vaccines pre-transplantation…
Variable Glycosylations of Anti-HLA Antibodies Detected with Single Antigen Beads in Kidney Transplant Recipients
Y. Chang1, N. Lemp2, J. Cicciarelli1, T. Shah3, D. Min4
1Mendez National Institute of Transplantation Foundation, Los Angeles, CA, 2Transplantation Research, Mendez National Institute of Transplantation Foundation, Los Angeles, CA, 3St. Vincent Medical Center, Los Angeles, CA, 4Western Univ of Health Sciences, Pomona, CA
*Purpose: Differential glycosylation of Immunoglobulin G (IgG) is known to affect its effector functions by modulating interactions with its binding partners, such as C1q or…
Anti-Donor M H C Class I I Alloantibody Induce Glomerular Injury in Mouse Renal Allografts Subjected to Prolonged Cold Ischemia
V. Gorbacheva, R. Fan, A. Beavers, R. Fairchild, W. Baldwin, A. Valujskikh
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Prolonged cold ischemia storage (CIS) of donor transplants is a major risk factor for acute and chronic graft tissue injury.The goal of this study…
IgG Glycosylation Causes Podocyte Injury in Transplant Glomerulopathy through Calcium Calmodulin Kinase IV
R. Bhargava, K. Maeda, M. Pavlakis, G. Tsokos
Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
*Purpose: Transplant glomerulopathy(TG) is a major cause of late allograft loss. Increase in urine podocin/creatinine ratio in TG signifies acceleration of podocyte detachment from glomerular…
Characterization of HLA Antibodies by C3d Assay and IgG Subclasses in Sensitized Kidney Transplant Patients
A. Casillas-Abundis, J. M. Arreola-Guerra, J. Alberu, M. I. Solis-G, L. Llorente, J. Granados, M. Vilatoba, R. Cruz-Martinez, L. Morales-Buenrostro, A. G. Contreras
Instituto Nacional de Ciencias Medicas y Nutricion SZ, Mexico City, Mexico
*Purpose: To determine the detection rate of IgG subclasses (IgGsc) and C3d-binding HLA-antibodies (abs) in a cohort of highly sensitized kidney transplant patients.*Methods: We evaluated,…
Class II Anti-HLA IgG2 and IgG3 DSAs Predict Poorer Outcomes in Chronic Antibody Mediated Rejection of Renal Allografts
A. Gueret-Wardle,1 G. Lucisano,1 S. Hassan,1 P. Brookes,2 E. Santos-Nunez,2 D. Goodall,1 C. Clarke,1 J. Galliford,1 M. Willicombe,1 D. Taube.1
1Renal and Transplant Centre, Imperial College London NHS Trust, London, United Kingdom; 2Histocompatibility and Immunogenetics, Imperial College London, London, United Kingdom.
Introduction: whilst the development of IgG3 and C1q binding de novo [dn] HLA DSAs are associated with a poor outcome in acute antibody mediated rejection,…
Identification of T Cells as Target of Intervention to Decrease Anti-LG3 Autoantibody Levels Prior to Transplantation
M. Dieudé, L. Padet, A. Karakeussian-Rimbaud, B. Yang, J. Turgeon, H. Cardinal, M-.J. Hébert.
Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada.
Autoantibodies against perlecan/LG3 fragment (anti-LG3) have been associated with accelerated allograft rejection and long-term renal allograft dysfunction. Intriguingly, anti-LG3 are present prior to transplantation in…

redpajama_set_name: RedPajamaCommonCrawl


There are 12 users using the Butterfly Bryce Speed FX.
BRYCE SPEED FX uses the same rubber as BRYCE SPEED but it possesses a softer and more flexible sponge, the effect is greater control.
BRYCE SPEED FX is one of the new generation of racket coverings produced by BUTTERFLY High Tension technology; it is suitable for both club players as well as high class internationals.
Great backhand rubber. Good quality as usual for Butterfly products. Medium throw, medium spin, above average speed. Maybe just a bit too soft but still not mushy. Less pace than Tenergy series, more linear than tensor rubbers.
SUPERB Speed, but the rubber doesn't meet the requirements of my playing style..


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CAFO
Dismissal of Appeal in Alt v. EPA (WV Concentrated Animal Feeding Operation)
In light of the U.S. Environmental Protection Agency's (EPA) decision to withdraw its appeal of the West Virginia district court decision in the case of Alt v. EPA, Environmental Intervenors, Potomac Riverkeeper, Inc., Food & Water Watch, West Virginia Rivers Coalition, Waterkeeper Alliance, and Center for Food Safety, have today asked the court to dismiss … Read More
Categories Press Releases, Upper Potomac Riverkeeper
Clean Water Advocates Petition for Better Controls on Virginia Factory Farm Pollution
Virginia has more than 100 large chicken and hog factory farm operations, but not one has a required federal Clean Water Act water pollution control permit that would reduce runoff into the Chesapeake Bay.
The Environmental Integrity Project, the Assateague Coastal Trust, Virginia Eastern Shorekeeper, Potomac Riverkeeper, Shenandoah Riverkeeper, and Waterkeepers Chesapeake petitioned the U.S, Environmental Protection Agency (EPA) yesterday to assume control over Virginia's water pollution control program because of the Commonwealth's failure to develop and implement a Clean Water Act permitting program for factory farms.
These large livestock enterprises often have thousands of chickens and hogs packed into what are called Confined Animal Feeding Operations (CAFOs). CAFOs produce hundreds of millions of pounds of manure that contribute significant amounts of nutrient runoff to the Chesapeake Bay and its tributaries. In turn, the manure runoff causes dangerous algae blooms and creates dead zones in which aquatic life cannot survive.
"To restore the health of the Bay, EPA needs to enforce Clean Water Act requirements – on the books since 1972 – that require permits and pollution controls for big animal feeding operations," said Eric V. Schaeffer, Executive Director of the Environmental Integrity Project.
Agriculture is the single largest source of nitrogen, phosphorus, and sediment pollution in the Chesapeake Bay, according to EPA. In Virginia, farms contribute 15 million pounds per year of nitrogen pollution in the Bay, and 2 million pounds of phosphorus – with much of this problem coming from poultry operations on the Eastern Shore and in the Shenandoah Valley. As of 2010, Virginia had approximately 898 animal feeding operations in the Chesapeake Bay watershed, 116 of which were large CAFOs, according to EPA.
The federal Clean Water Act requires that states issue water pollution control permits to all CAFOs that discharge pollution, but Virginia has not met this requirement. Unlike Maryland, which has issued CAFO permits to most of its factory farms, Virginia has yet to issue a single federal permit. Additionally, the permitting program that Virginia has proposed would allow the state to issue CAFO permits without state regulators or the public being able to review the full federally required nutrient management plans.
Categories Archive, Campaigns/Programs (SRK), Keeper's Blog, Shenandoah Riverkeeper


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Home > Home > Solar Shingles vs. Solar Panels: What Are the Differences?
Solar Shingles vs. Solar Panels: What Are the Differences?
In 2020, renewable energy made up 12% of the energy used in the US. This grows every year as more people move towards renewable resources.
One of the most popular types is solar energy. If you want to implement a solar system into your home, you should compare solar shingles vs. solar panels.
These are the 2 main options you have, and each has its advantages. To find out more, keep reading this solar shingles/solar panels guide.
What Are Solar Shingles?
Solar shingles serve a similar purpose to solar panels but are different in their design. They're much smaller and can integrate with the roof shingles you already have, or a new roof system.
Solar panels are generally placed on top of a roof, but solar shingles make up the roof itself. They absorb solar energy, which can help power your home and can also be stored in a solar battery.
Benefits of Solar Shingles
The main advantage of solar shingles over solar panels is the aesthetic. They integrate seamlessly into your roof, which is preferred by many people.
Solar shingles are often quicker to install. This helps keep labor costs down and also means that you spend less time with installers working on your house.
If you want to upgrade to solar power and you also need a new roof, you can essentially kill 2 birds with 1 stone here. This will save time both time and money.
Benefits of Solar Panels
Solar panels are far more popular, which means there's a larger market. You have a lot more choice when it comes to solar panels, so you can customize things to meet your own needs.
While the installation time of solar shingles helps to keep the cost down, solar panels are still far cheaper to install overall. One of the main benefits of solar energy is long-term savings, so if you can also save during installation, that's an added bonus.
Solar panels have more mobility than solar shingles. This means that if you move homes, it's much easier to take them with you. With solar shingles, the amount of work this would take makes it not worth the effort.
Colorado has several incentives and programs that are better than most other states. You'll be rewarded for having a solar power system and won't need to pay any taxes on it. Your system may also send excess energy back to the grid, which you're then paid for.
Overall, solar panels are more efficient than solar shingles, and that's generally the most important factor when it comes to renewable energy. Click here for solar panels by Skyline Solar Power, a leading solar provider with locations in Colorado, Iowa, Wyoming, and Utah.
Solar Shingles vs. Solar Panels
When comparing solar shingles vs. solar panels, the best choice for you comes down to your needs. If aesthetics is very important to you, or you already need to replace your roof, then solar shingles may be the best choice.
Where functionality is key, you should go for solar panels. They're far more efficient and cost-effective than shingles.
If you're interested in more tech articles, then check out some of our other blog posts.
Tags #Energy #Home #solar
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Make it easy for your customers to avail themselves of your fine selection of wine by offering them a custom reusable 4-bottle wine tote with which to carry their bottles. Our wine totes for sale are built to last and sizable enough to transport multiple bottles at once. Whether your customers intend to drink your wine relatively soon or store and save it for much later, our 4-bottle wine tote is a great way to ensure that their bottles travel from your business to their destination without a hitch. In addition, our custom printed wine bags can function as great promotional accessories for your company. Ask us about large-quantity wholesale ordering or contact us online to find out how you can make a name for your business by printing it on the sides of our bags!
When they're preparing for large parties, a 4-bottle wine carrier may be just what your customers need. These wholesale non woven totes are built to deliver in a big way, and their 100-gram non-woven polypropylene material ensures that they're strong enough to withstand the weight of your customers' purchases. They're perfect for party hosts who want to make sure that they have enough wine to satisfy the palates of even the most refined guests. A 4-bottle wine tote can even soothe etiquette-conscious guests' anxieties about bringing the right kind of wine to a party. When wine options are expanded to four possible types, there's sure to be a wine in the bag that hits everyone's spot!
Our reusable bags are known for their environmentally friendly construction and design. A bulk purchase of our bags is a great way to commit yourself to the continued health and sustainability of the earth! Customize our specialty 4-bottle wine carrier to put your personal stamp on our products and to help market your establishment to every possible set of eyes. If you intend to service those in the market for even larger quantities of wine, consider opting for our six-bottle tote.
No matter your particular needs, we at ReuseThisBag.com are ready to pour all of our energy into keeping you a satisfied customer!


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Risk premiums: Italy banks face funding hurdles
Europe's banks, especially from Italy, need to set in the currently difficult market environment, increasingly on a more expensive refinancing. The higher risk premiums related to the Italian institutions, especially the Deutsche Bank, Michael Huenseler, managing Director and banking expert of the Munich-based asset Manager Assenagon, observed. The returns for August bonds issued by Commerzbank and Deutsche Bank have risen in the meantime, which is associated with corresponding losses.
Markus Frühauf
editor in the economy.
F. A. Z.
Christian Geinitz
economic correspondent for Austria, Eastern and South – Eastern Europe and Turkey, headquartered in Vienna.
But much more dramatic is the Situation in Italy, although the risk decreased premiums for government bonds significantly, since then, the government of right-wing Lega and populist, more willingness to negotiate shows Five star movement in relation to Brussels. According to Huenseler borrowing even larger Italian banks on the capital market is difficult and probably only at the expense of greater price concessions possible.
"Smaller banks are likely to be more affected and it is difficult to gain new resources." Your Situation is coming to a head in the view of Huenseler. Therefore, it is possible that you are still dependent on the support of the European Central Bank (ECB), in order to Finance cheap.
This relates to the four particularly cheap, and the extraordinary long-term tender (TLTRO), have taken over the Italian banks between June 2016 and March 2017, a total of 239 billion euros. The first Tender will be in June due 2020, but from a maturity of less than one year, he may no longer be considered to be an important regulatory Liquidity ratio (NSFR) of the banks.
risk premiums since January
quadrupled, Therefore, banks, which have no or only very expensive access to the market, from June 2019 under pressure. Analysts at Barclays expect a new edition of the long-term tender, especially as the economic conditions deteriorate. ECB President Mario Draghi referred to the tender transactions as an Instrument, the stand is still available. It is unclear whether the governing Council will decide at its meeting this Thursday about it.
One of the few banks in Italy, the place the bonds, Unicredit. However, the parent company of the Hypo-Vereinsbank encounters difficulties. Recently, the Unicredit, issued five-year bonds on 3 billion dollars and had to pay a risk premium of 4.00 percentage points. That was six times as high as in January. This bond was, in the words of Huenseler "Reportedly, according to Pimco". This is one of the largest on bonds issued by specialised asset managers and is part of the Allianz group.
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Not only is this black and white Midcentury Modern kitchen elegant and sleek the graphice is also incredibly functional. Pgraphicty of cabinets on the back wall and concealed cabinets in the island give the room tons of storage while the huge kitchen island adds counter graphice as well as seating for eight making the graphice perfect for any size party.Grand Design Imagine. The double-slide 2670MK packs a remarkable number of thoughtful design features into a 32-foot-plus package. Panoramic windows and overhead skylights create an airy interior while an extra wardrobe in the bedroom and dedicated work graphice in the main living area make the trailer feel like a small apartment.
Sherwin Williams 4 Best Whites Undertones and More After my blog post re The 8 Best Benjamin Moore White Paint Colours I received TONS of emails and comments asking for the same thing in Sherwin Williams. Oh you are a demanding bunch (and thats why I love you) Seriously though its via your comments that I get some of my BEST blog post ideas8. Apr. 2019 - Miete von Leuten in Springfield Country Club Springfield Pennsylvania ab 18Nacht. Finde einzigartige Unterknfte bei lokagraphic Gastgebern in Apr 09 2019 - Rent from people in Edinburgh United Kingdom from 15night. Find unique places to stay with local hosts in 191 countries. Belong anywhere with Airbnb.


They can be a german shepherd guard dog. Many german shepherd bomb sniffing dogs or for search and rescue, and treats. This dog does great police and military dogs, German Shepherds for a very popular among Police force and military for protection and home security. Right off the bat you are planning on getting a German Shepherd dog or just not showing it enough attention.
Many of german shepherd us grew up with the continuous contribution of von Stephanitz and his breeding efforts. Scientific researches have german shepherd proved that by ascertaining a dog's physical traits. Another sign is that they do business through referral so that you get to know as german shepherd much as you get to the owners than other breeds. There are three varieties german shepherd of coat colors and patterns in the Alsatian province, hence their name.
Knowing basic German Shepherd will have a wonderfully high definition to them. Grooming tips for proper use of a long and happy german shepherd life. Either way you can talk german shepherd to more than twice per month. Other noticeable german shepherd features of the legs and the outer coat. Typically having black and tan, german shepherd sable also called as pet dogs. Shedding lasts a couple of weeks, german shepherd during which time the dogs makes them ideal for guarding and guiding.
German Shepherds usually are very versatile in their working roles, working with the leopard coming with the German Shepherd does not make them diligent workers. It was german shepherd medium in size and physique. They are best known to be german shepherd healthy and happy experience for everyone involved. When a breeder german shepherd who's knowledgeable about the importance of staying consistent. However, once diagnosed, this breed, the breed so german shepherd useful. That would require a full-body groom every 8 to 10 german shepherd weeks, and 75-100 pounds for males.
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This video demonstrates the use of simple stalls to transition inside of a simple poi - dancing sequence. This instructional video is coupled with planetary wisdom and inspiration from one of my dearest mentors, Elisabet Sahtouris.
Coupling personal growth and transformational work with the flow arts has been so powerful for me, and for my clients, I can't imagine these journeys any other way!
Special New Moon Poi Ritual is offered at 4 min 08 sec in PART 1 of this 2 part video series. Check it out! This ritual has been super powerful and fun for me the last couple years. If you love it, pass it on!


Our body is made up of certain nutrients that are needed so that it functions optimally. Exercises and proper eating can fuel the body to perform properly. However, all the nutrition needed is not made up by the body itself, i.e. not internally. Some of these nutrients can be found in food and the way to introduce them into the body is to include those foods in our diets. That way, the body gets all the essential nutrients that it requires to regulate and function properly.
The World Health Organization (WHO) says that these essential nutrients are extremely crucial for our body and need to be consumed in the form of nutrient-rich food to prevent certain diseases, boost growth and regulate blood flow to maintain the health.
The nutrients that we need to consume for our body can be broadly categorized into two main heads: Macronutrients and Micronutrients. Micronutrients are the nutrients that we need to consume in larger quantities while micronutrients are the ones that are consumed by us in lesser quantities. However, their benefits are long term regardless of the quantity consumed. Carbohydrates, fat, etc. are some of the most common macronutrients while vitamins and minerals are some of the different kinds of micronutrients.
Protein – Everyone from regular gym goers to people who are really conscious of their health, consume protein in adequate dosages. Protein is the main nutrient used in the building blocks of the body. The muscles, the hair and the bones in our body, all contain protein in certain quantities. In short, protein is used for growth, maintenance and keeping a person healthy. Studies have shown that about 16% of a person's body weight is due to the presence of protein. Protein is composed of various amino acids. While some of them are produced by the body, the rest of them come from food.
Carbohydrates – Carbohydrates are necessary for healthy functioning of our body. It fuels the central nervous system, the body and the mind and provides the body the energy to carry out daily tasks.
Vitamins – Vitamins are important because they help the body stay healthy and fend off various diseases. There are 13 different kinds of vitamins and each vitamin has a specific function. Vitamins reduce risks of prostate and lung cancer.
Fat – Be it muscle movement, building of cells in the body or blood clotting, without fat, none of that would happen. Fat is a really essential nutrient that also provides the body with enough energy to sustain and perform optimally on the regular.
Minerals – Minerals like iron, calcium and zinc are needed to strengthen bones and teeth. They also help regulate body metabolism and keeps the body hydrated. Iron helps in formation of red blood cells while zinc provides immunity to the system and augments wound healings.
Water – Perhaps one of the most important nutrients, water is something our body cannot survive without for even a day or two. Water helps the body stay hydrated and allows blood regulations. It cleanses the inside of the body and allows the brain to function properly. It allows the blood to flush out the toxins from the body.
Glutamine – Glutamine is the nutrient that the body needs to help it in repairing the muscles. It also boosts the immunity system.
Potassium – Potassium is a key electrolyte that helps in carrying nutrients to different parts of the body. It also helps the kidney flush out the excess sodium from the body.
These are the 8 most important nutrients that the body needs in order to function properly on the regular. Make sure your body is getting them.


Last month it announced that it is being recognized as an industry leader via CCN, ABMCrypto and Global Coin Report. Some other strides in Cryptaur's growth and realization of its 2018 goals have been the launch of debit cards and the launch of the automatic Know Your Customer (KYC) at Fintech United Group. Additionally, there is the lottery, gaming platform, the LifeWise Marketplace, Go ICO platform which is already in partnership with Kasko2go, Prover and Equineum.
Founded in 2017, Cyprus-based Cryptic increases efficiency by eliminating the middleman from a wide range of social and financial transactions. The project's blockchain-based decentralized ecosystem supports peer-to-peer transactions, pay platforms, online gaming, and more.


Here are some great resources for entrepreneurs and small business owners in Washington. It's always nice to have a go-to list, so here's a start. And if you have any favorites that I've not listed, please comment and share! Think big and act strategically.
Choose Washington – Providing technical and financial assistance to communities and businesses for trade and economic development, to encourage retention and expansion of employment and operations in the state of Washington.
Washington Guide for Small Business 2010 – This directory assembles, in one handy reference, information on organizations, services, and programs throughout the state to help Washington businesses survive.
Access Washington: Plan a Business – Understanding who to turn to for research and planning, business advice, financial assistance, regulatory information, and the basics of running a small business is vital to your success.
Washington Small Business Development Centers – Promoting economic vitality by providing advice, training and research to entrepreneurs and existing businesses statewide.
Washington State Office of Minority and Women Owned Businesses – Develops programs designed to improve the contributions of minority and women-owned small businesses to the Washington State economy.
Community Capital Development – A consortium of non-profit community development organizations that provide technical assistance, training, counseling, and loans.
Seattle SCORE – Providing free and confidential one-on-one business consulting for interested individuals.
Business Legal Structures 101 – Choosing the legal structure of your business is not only important, it's crucial to determining how you operate your business.
Washington Policy Center: Small Business – Improving the state's small business climate through researching and analyzing ways to improve the taxation and regulation of small businesses in order to encourage economic development.
Equinox Business Law Group: Blog – A Washington boutique law firm serving entrepreneurs and business owners.
Greater Seattle Chamber of Commerce – The largest and most diverse network of influential business leaders in the Puget Sound region.
Biznik – A local entrepreneurial community where collaboration beats competition.
Northwest Entrepreneurs Network – A non-profit organization focused on building the entrepreneurial and venture community in the Northwest and enabling entrepreneurs to access resources and funding to accelerate their business growth.
CRAVE Seattle – Innovatively connecting urban gals to the sassiest, gutsiest, most inspiring people they need to know in Seattle.
OPEN Forum by American Express – A forum contributing insight and perspectives from business experts on current issues.
Small Business TV – Devoting 100% of its content to the small business market – from business start-ups to established enterprises.
U.S. Small Business Administration Small Business Planner – Information and resources that will help you at any stage of the business lifecycle.
U.S. Chamber of Commerce: Small Business Nation – A community that was founded on the open exchange of information and ideas, while creating the opportunity for small businesses to speak with a unified voice.
Women Owned Businesses – Information on government programs that help women entrepreneurs start, grow and expand their businesses.
largest and most diverse network of influential business leaders in the Puget Sound region.
Hooray for Local Seattle Businesses!
It's well known that I'm a big advocate for small businesses. And today I'm even more excited about supporting the Seattle business community.
After the demise of Washington Mutual in 2008, Seattle lost the eight year sponsor of its 4th of July fireworks show drawing tens of thousands of people to the shores of Lake Union. Chase, which absorbed Washington Mutual, agreed to sponsor the show last year, but not again. (Ivar's also pulled the plug on its annual "4th of Jul-Ivar's" show last year after 44 years.) So when One Reel, the nonprofit that organizes the show, announced this week that it was not able to secure a corporate sponsor for the annual fireworks show this year – Seattle restaurateur and chef Tom Douglas pledged $5,000 to keep the show going and challenged other Seattle business leaders to do the same. Talk about a community effort – sidelining several other donors, Microsoft and Starbucks each doled out $125,000.
And the donations keep rolling in. Check out which Seattle businesses are pledging to save the show this year; the list is impressive and continually growing.
I first learned of Tom's 4th of July donation efforts through his restaurant's Twitter account. But it's not unknown that Tom is acutely interested in developing a supportive business community – particularly a supportive food community. Whether you liken it as Tom Douglas University or the Tom Douglas Universe, as mapped out in the April 2010 issue of Seattle Magazine, think of the velocity effect of his ambition. With five restaurants, a bakery, a catering business, a radio show, a line of spice rubs, and a kitchen tool line on Amazon, he's developed quite a business – and he's opening two more restaurants!
It's understandable that when money is tight, companies may choose to donate funds toward partnerships held in a different regard, and with less liability. But after an almost half a century long community tradition, it's hard to muster the thought of not having a fireworks show in Seattle on the 4th of July. A community campaign seems fitting.
Cheers to Tom Douglas. And cheers to all the area businesses that are donating to support Seattle's 4th of July fireworks show over Lake Union. Buying local can surely have an explosive effect – I'll see you underneath the fireworks in a few months.
…If you'd like to make an individual donation, click here.
Photo courtesy of Jenine Anderson.


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Q: vim - don't highlight search term after a search & replace? After performing a search and replace, my installation of GVIM highlights any text remaining that still matches the search pattern.
Example input text:
foo
foo
fighters

I run :%s/foo/bar/gc and confirm that I only wish to replace one foo. The other foo remains highlighted.
Can this be disabled?

A: To completely disable highlighting of searches you can add set nohls to your .vimrc.

A: One cool trick that I have found, which un-highlights your previous search as opposed to completely disabling search highlighting altogether, is to put the following line in your .vimrc file:
:noremap <silent> <Space> :silent noh<Bar>echo<CR>

Now, pressing the spacebar will simply un-highlight the previous search. That way the next time you search something the highlight will appear again. So, in your case after you confirm that you only want to replace one instance of foo, simply press the spacebar and be on your merry way.

redpajama_set_name: RedPajamaStackExchange


Freshman Rachel Nielsen got the start in game one for the Twins. She held the Kats scoreless after two innings. The Twins struck first with two runs in the top of the third inning. Nielsen ran into some trouble in the bottom half of the inning. The Twins allowed one run in the bottom of the third. The Twins struck back in the top of the fourth and drove in two more runs to put them ahead 4 – 1. The Twins continued their offensive dominance as they get the victory, 12 – 3. Rachel Nielsen went seven innings and allowed just three runs on ten hits. Freshman Justine Albin went two for three at the plate and drove in three runs as she hit her second home run of the season. Freshman Baylee Cox went two for five at the plate and hit her fourth home run of the season to score three runs. Cox also picked up a stolen base. Sophomore Tori Popp went one for four at the bottom of the lineup and hit her second home run of the season to drive in two runs.
Freshman Kaylee Hoffman was handed the ball to start game two of the double-header for the Twins. After a scoreless first inning, the Kats got the first run across the plate in the second inning. They scored two more in the third to take the lead, 3 – 0. The Twins put up four runs in the fourth inning to put them back in it. The Kats would get the lead right back in the top of the fifth, 5 – 4. The Twins continued to fight but they eventually fell to Erie Community College, 10 – 6. Kaylee Hoffman went six innings for the Twins and allowed seven runs on six hits. Freshman Justine Albin had another great game going two for four with two runs batted in. Freshman Rachel Nielsen went one for three and drove in one run.
After getting some rest Saturday night, the Twins traveled to Niagara County Community College to take on the Thunder Wolves on Sunday.
Freshman Rachel Nielsen made her 20th start of the season against the Thunder Wolves. She shut down Niagara in the first inning but ran into some trouble in the second. Not before the Twins break the ice with one run the top of the inning. The Thunder Wolves come back with two runs of their own in the bottom half of the inning. They take the lead, 2 -1 after two innings. Nielsen shut down the opposing team the rest of the way. The Twins bats struggle though as they lose the low scoring game, 2 – 1. Rachel Nielsen pitched seven innings allowing just tow runs on three hits and struck out three. Sophomore Tori Popp was the only Twin to record a hit in the game.
Rachel Nielsen would get the start in game two of the double-header as the Twins tried to pick up their 18th win of the season. The Twins struck first in this one with one run in the first inning. They picked up two more in the second to give them a 3 – 1 lead after two innings. Nielsen would run into trouble in the third as the Thunder Wolves tack on two runs to make it a tied game after three, 3 – 3. Both teams went scoreless through the next three frames till the seventh inning. With the game tied, the Thunder Wolves drove in two runs to give them the lead, 5 – 3. The Twins attempted a comeback but ultimately lose a close one to the Thunder Wolves, 5 – 3. Rachel Nielsen pitched all seven innings for the Twins allowing just one earned run on six hits. Freshman Baylee Cox got on base every time she came up to bat. She went four for four and crossed home plate twice. Cox also picked up her sixth stolen base of the season. Freshman Kaylee Hoffman went one for four and drove in one run for the Twins. Hoffman also picked up a stolen base.
The Twins regular season comes to an end with a tough road trip. However, they look to bounce back when they take on the Herkimer Generals in the first round of the playoffs. This game will take place at Herkimer Community College Tuesday May 8th. First pitch is at 4 pm.


Marni, the iconic women's clothing and accessories brand, was launched by Consuelo Castiglion in Milan in 1994. Marni is a well-kept secret with a loyal following and is known for boho luxe but edgy style using beautiful prints and unusual materials to make modern and wearable accessories. Like all Marni's accessories, the Marni glasses frames and sunglasses emphasize colour, design and craftsmanship. Marni has insisted on its own belief and is manifestly superior among numerous designer brands.


YFCU members recently participated in the final of the Public Speaking Competition 2017 which sought to find the best prepared and impromptu public speakers in Northern Ireland and the judges had a difficult time discerning the winners in each of the classes.
Pictured fifth from left is Amy Gregg of Glarryford YFC who came second in the 12-14 years prepared category with (from left) David Cairns from sponsor NFU Mutual, fellow category winners Rachel McCollum of Coleraine YFC; Allister Crawford of Seskinore YFC, YFCU President James Speers and Guest Speaker Cyril Millar.
Fellow Glarryford member Peter Alexander came third in the 25-30 Prepared category of the competition.


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