text:
Home Center Well Polis set to introduce bill to allow states to legalize marijuana
Polis set to introduce bill to allow states to legalize marijuana
Scot Kersgaard
Rep. Jared Polis (Kersgaard)
U.S. Rep. Jared Polis plans to be a co-sponsor on legislation Thursday to allow states to legalize marijuana without federal interference.
Rep. Barney Frank, D-MA, and Rep. Ron Paul, R-TX, announced today they will introduce the bi-partisan legislation Thursday, June 23, in an attempt to end the federal war on marijuana and let states legalize, regulate, tax, and control marijuana without federal interference. Besides Polis, co-sponsors include Rep. John Conyers, D-MI, Rep. Steve Cohen, D-TN, and Rep. Barbara Lee D-CA.
Reached by email, Polis said, "It's time for the federal government to end the 40-year failure that has been the war on drugs. Colorado has shown that marijuana can and should be regulated at the state level. Instead of wasting money enforcing a prohibition that doesn't work, we should create jobs, increase local tax revenues, and make our communities safer by de-federalizing marijuana policy and allowing state-approved, legal medical marijuana businesses to continue free of federal interference."
The legislation would limit the federal government's role in marijuana enforcement to cross-border or inter-state smuggling, allowing people to legally grow, use or sell marijuana in states where it is legal. The legislation is the first bill ever introduced in Congress to end federal marijuana prohibition.
46.5% of Californians voted last year to legalize marijuana in their state, and voters in Colorado, Washington and possibly other states are expected to vote on the issue next year. In the past year at least five state legislatures have considered legalizing marijuana, including California, Maine, Massachusetts, Rhode Island, and Washington. 16 states and the District of Columbia have legalized marijuana for medical use, but the federal Drug Enforcement Administration (DEA) continues to arrest people under federal law and U.S. Attorneys have in recent months sent threatening letters to state policymakers in an apparent attempt to meddle in state decision-making.
The legislation would end state/federal conflicts over marijuana policy, reprioritize federal resources, and provide more room for states to do what is best for their own citizens, Frank and Paul said in a press release.
Montana State Rep. Diane Sands told the Colorado Independent earlier this month that she was trying to organize national support for just such a move by the federal government.
Jared Polis
legalize marijuana
Scot Kersgaard has been managing editor of a political newspaper, editor and co-owner of a ski town newspaper, executive editor of eight high-tech magazines (where he worked with current Apple CEO Tim Cook), deputy press secretary to a U.S. Senator, and an outdoors columnist at the Rocky Mountain News. He has an English degree from the University of Washington. He was awarded a fellowship to study internet journalism at the University of Maryland's Knight Center for Specialized Journalism. He was student body president in college. He spends his free time hiking and skiing.
To a sea of MAGA hats, Polis promises 'a Colorado for all'
2019 Colorado legislature
Colorado vaccine skeptics heartened by 'pro-choice' Jared Polis
Colorado prison inmates can now receive greeting cards. Are free phone calls next?
Major Western cities pay residents to rip out their lawns to...


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La Junta de Representantes de los Departamentos fue un órgano colegiado que ejerció de facto el poder legislativo de México entre el 3 de enero y el 4 de enero de 1846. Fue nombrado a consecuencia del golpe de Estado que el 30 de diciembre de 1845 elevó al poder a Mariano Paredes y Arrillaga y tuvo como principal objetivo nombrarlo presidente interino de México.

Antecedentes

Desde su independencia de España en 1821, México había sufrido una crónica inestabilidad política que lo había llevado a pasar sucesivamente por formas de gobierno tan disímbolas como el primer Imperio, la primera República Federal y una república Centralista; así como la vigencia de tres diferentes constituciones.

Los partidarios del Centralismo había triunfado en el año de 1836, cuando el 6.° Congreso Constitucional se había declarado a sí mismo constituyente y había procedido a emitir y promulgar un nuevo texto constitucional que sustituyó a la Constitución federal de 1824 y consagró el centralismo en las denominadas Siete Leyes Constitucionales de la República Mexicana.

De acuerdo a esta constitución fue elegido presidente de México a partir de 1837 el Gral. Anastasio Bustamante. Quien sin embargo se enfrentó a numerosas insurrecciones nacionales y a dos conflictos internacionales: la insurrección que declaró la Independencia de Texas y el primer enfrentamiento con Francia, conocido históricamente como la Guerra de los Pasteles.

Bustamente fue derrocado a finales de 1841 por un pronuciamento militar iniciado en agosto de ese año en Jalisco por Mariano Paredes y al que se sumó Santa Anna en Perote y Gabriel Valencia en la Ciudad de México. Triunfantes, los sublevados redactaron un plan conocido como las Bases de Tacubaya, que elevaron nuevamente a la presidencia a Santa Anna, con el fin nominal de llamar a elecciones a un nuevo congreso constituyente, pero que en realidad le entregaron el poder absoluto.

Tras varias vicisitudes, un congreso denominado Junta Nacional Legislativa, promulgó una nueva constitución, también centralista, conocida como las Bases de Organización Política de la República Mexicana y que pasaría a la historia con el nombre común de las Bases Orgánicas. De acuerdo a esta constitución fue elegido un nuevo cuerpo legislativo, que inauguró su 1.° Congreso Constitucional el 1 de enero de 1844. En noviembre de ese mismo año, Mariano Paredes volvió a levantarse en armas en Guadalajara, y Santa Anna dejó entonces la presidencia para combatirlo, quedando como interino Valentín Canalizo; éste, por orden de Santa Anna, disolvió el Congreso el 1 de diciembre, pero seis días después, el 6 de diciembre, una insurrección general de la Ciudad de México derribó el gobierno de Canalizo, restableció el congreso y elevó a la presidencia al Gral. José Joaquín de Herrera. Herrera envió entonces a su primer exilio al derrotado Santa Anna.

El gobierno de Herrera se dedicó entonces a enfrentar la inevitable guerra contra Estados Unidos que se había iniciado el proceso de anexión de Texas el 1 de marzo de 1845. Se equipó un ejército de seis mil elementos que fue puesto al mando de Paredes y partió rumbo al norte. Pero el 14 de diciembre, al llegar a la ciudad de San Luis Potosí, Paredes se rebeló publicando un Plan que desconocía el gobierno de Herrera y retornó en rebelión a México, encabezando un golpe de Estado que concluyó cuando el 30 de diciembre se levantó en armas en la capital en su apoyo Gabriel Valencia. Ante ello, el mismo día y al verse sin apoyos, José Joaquín de Herrera presentó su renuncia ante el Congreso, que no logró el quórum legal requerido para reunirse y de hecho quedó disuelto a conscuencia. Al día siguiente, 31 de diciembre, Mariano Paredes y Arrillaga entró triunfante en la Ciudad de México.

La Junta de Representantes de los Departamentos

Entonces, y para dar justificación al nuevo régimen militar, el 2 de enero de 1846, los generales y jefes de cuerpo de ejército que apoyaron la insurrección se reunieron en el Palacio Nacional y suscribieron un acta en donde establecían que ante la disolución de los antiguos poderes Ejecutivo y Legislativo, y de acuerdo con el Plan publicado en San Luis Potosí el 14 de diciembre anterior, el general en jefe del ejército —Paredes— nombraría una Junta de Representantes de los Departamentos, formada por dos individuos naturales o vecinos de cada uno de ellos, que procedería de inmediato a nombrar un Presidente Interino de la República. Este, debería de proceder ocho días después a convocar a la elección de un Congreso Extraordinario que debería de redactar una vez más, una nueva Constitución. Tras designar presidente interino, la Junta de Representantes debería de disolverse.

Integración
Mariano Paredes y Arrillaga procedió entonces a nombrar la citada Junta, a la cual fueron designados numerosos integrante del Congreso Constitucional disuelto en diciembre y que quedó integrada por los siguientes individuos:

Elección del presidente y disolución
Al reunirse los representantes y antes de constituirse formalmente, eligieron como su presidente al Arzobispo de México, Manuel Posada y Garduño; y al quedar constituida formalmente, resultó elegido para dicho cargo José María Tornel.

Inmediatamente procedió a la elección de presidente interino de la República, siendo electo por unanimidad de los 43 presentes Mariano Paredes y Arrillaga —que ya ejercía el cargo de facto desde el 30 de diciembre—, participándole a éste su nombramiento, fijando para el día siguiente 4 de enero su protesta de ley y estableciendo para ello la siguiente fórmula de juramento:

El día 4 de enero tuvo verificativo la toma de posesión de Mariano Paredes, y al término de la cual, declaró haber cumplido las funciones para las que había sido nombrada y se cerró la sesión.

Véase también
República Centralista (México)
Anexo:Congresos y Legislaturas del Congreso de la Unión de México

Fuentes

Legislaturas de México
México en 1846

redpajama_set_name: RedPajamaWikipedia


text:
package com.zxr.medicalaid.mvp.presenter;

/**
 * Created by ASUS-NB on 2017/8/3.
 */

public interface UpLoadPrescriptionPresenter {
    void upLoadPrescription(long linkId,String message);
}

redpajama_set_name: RedPajamaGithub


Eli A. Martinez entered into eternal rest on April 9, 2019. Eli was born on January 2, 1954 in Morenci, Arizona to Benny and Olivia Martinez. Eli had one brother; Alex Martinez.
Eli attended Safford High School and was a member of the graduating class of 1972. He loved music especially classic rock and the era of the 1970's. Eli worked as a cable installer.
He is survived by his 4 children; John Martinez (Julie), Eric Martinez (Pilar), Ondrea Martinez (Jasko), and Issac Martinez (Cristine), his brother Alex Martinez (Jerri) as well as Jeff and Jorden.
He was preceded in death by his Parents; Olivia and Benny Martinez.
A graveside service will be held on Thursday, April 18, 2019 at 10:00 a.m. at the Safford Cemetery.


text:
Medical Marijuana Advocate Zito Hopeful of Scutari's Leadership
Original Source:
Submitted by jane 1 year 1 month ago
Jo Anne Zito of the 'Coalition for Medical Marijuana – New Jersey' believes that the new year will be a good one for the state's medical marijuana patients, equity, and also for social justice. She cited the departure of Senate President Stephen Sweeney, replaced by Senator Nick Scutari, as a reason to be optimistic for 2022. "There is cause for hope," Zito told Insider NJ. "Scutari is a little bit better on cannabis. He seems to definitely want to remove the felony issue, maybe make it a misdemeanor."
Zito is a staunch advocate for New Jerseyans to be allowed to grow their own medical cannabis, something she says every state which has passed legalization allows to some degree, with the exception of New Jersey. The reason? Follow the money, as the old saying goes. "They want to track it from seed to sale as much as possible and, I think, control the price." Zito said that without competition, cannabis prices will not come down as per normal market forces, and that in the present situation, medical marijuana remains very expensive. She was also concerned about quality control issues such an arrangement represents. "Honestly, I think that is one of the reasons why they did that, and homegrown cannabis doesn't fit into it. Sweeney was against it and with Sweeney out, it does give me hope."
As far as Gordon and Elizabeth's disappointment with the product of the referendum was concerned, Zito was more sanguine. "The referendum doesn't actually say [retail], it really just says regulating the sales and use. The way that the ballot had it titled, legalization of marijuana, well, I was reading an article that said, statistically, most people don't even read past the title. It goes to explain that they're legalizing a form of marijuana called 'cannabis' and that they're legalizing adult use and sale, and it's going to be regulated by the Cannabis Regulatory Commission. But at the top it says 'legalize marijuana', which they conveniently did not legalize. They left that as the term for illicit cannabis, which is also considered, legally, a schedule one drug. So, if it's not from a regulated facility, then it's not legal."
New Jersey Legalization
Sen. Nicholas Scutari
Gov. Phil Murphy
Jo Ann Zito
Cannabis Home Cultivation
HomeGrow
Adult Use Cannabis Sales
join njlegalize.me
please consider registering for an account with njlegalize.me
members can rate and review medical marijuana dispensaries and doctors.
help educate others who want to learn more about New Jersey medical cannabis.
twitter sign-up
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get your NJMMP card!

redpajama_set_name: RedPajamaCommonCrawl


text:
https://www.nist.gov/itl/iad/mig/video-surveillance-technologies-retail-security-visitors
Search NIST
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Video Surveillance Technologies for Retail Security (VISITORS)
The U.S. Retail Industry experiences over $32B in losses per year (2008 statistics) due to retail theft and frauds. Organized crime accounts for a staggering portion of these losses. Current video surveillance networks rely heavily on an eyes-on approach to alerting officials of specific human-related behaviors. Unfortunately, humans are unable to maintain focus and attention across several video monitors for an extended period of time. Improved video behavioral analytics will serve to alert loss professionals and security personnel to behavioral abnormalities, direct their attention to the monitor and area of interest, and allow them to engage with the shoplifter before departure from the store. This will have a dramatic impact on Industry and our overall Economic Security. Improved technologies in the "Commerce" environment are directly applicable to improvements needed to notify police and security forces of potential threats. Hence, VISITORS receives a lot of attention from several communities.
The VISITORS project goes a step beyond any video analytic work done to date, in the sense of promoting the advancement of video analytics that are able to predict that a criminal event is about to take place through the observation of specific behaviors. This is done by predictive analysis, using software to analyze a video stream and to identify suspicious behaviors that enable notification of security personnel while tracking the person of interest up to, and including, the shoplifting event. The VISITORS project will require the development of a distributable video data corpus of normal and abnormal activities encountered in a retail environment.
As a direct result of the June 2010 Technical Symposium several senior-level working groups were developed and began meeting in the latter portion of 2010. The active working groups are:
Suspicious Behaviors which encompasses law enforcement, psychologists, senior loss prevention officials, computer vision experts, and scientists. Intense brainstorming produced a list of salient external, internal and group behaviors which may be precursors to a shoplifting event.
Strategic Planning which is comprised of government only personnel and is looking at steps forward in evaluation protocols and planning.
Video Data Collection which met to discuss the various issues involved in collecting and disseminating video for training and testing algorithms. Options for using existing retail video databases and alternatively creating scenarios, based on desired suspicious behaviors, are being pursued. The group discusses a myriad number of issues, not least being dealing with legal issues concerning use of Human Subjects in research.
The heaviest push is focused on receiving clearances for data access and dissemination. Human subject protection and personal identifying information concerns must be resolved. Much effort remains in developing scenario based data collection protocols.
Efforts to develop the VISITORS Evaluation plan and metrics for an initial pilot evaluation are underway.
Past Activities:
2010 Technology Symposium for Video Surveillance Technologies for Retail Security
NIST has brought together major stakeholders from the retail and security industries, computer vision technologists/developers, the research community, law enforcement, and government agencies in a common mission to advance the state-of-the-art in predictive video analytics. The focus of the VISITORS project is to advance technologies and methodologies used to detect persons engaged in suspicious activities as applied in the retail domain. The initial "meeting of the minds" was held via a technical symposium in June 2010 to identify interest and key issues among the stakeholders. The resulting roadmap indicating the pathway ahead is now available.
Information technology, Biometrics, Data and informatics, Data and informatics, Data and informatics, Data and informatics, Law enforcement, Law enforcement, Law enforcement and Forensic Science
Created March 12, 2010, Updated August 25, 2016
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Fiamm Italian bus horn set. A 12v air horns set with a dual alternating sound. Often used by buses in Italy as a warning signal for oncoming traffic.
alternative for the regular Tour Horn.
A wiring schedule (several options) is included.
It is not plug and play, but with a little technical knowledge you'll be fine.
you can always ask your garage to help you.


First product picture is showing the particular leash.
Love is a four-legged-word, right? According to us, it is and of course we want our furry ones to be able to walk the talk too. This collection is one of a kind leashes made out of leftover textiles from our base production and these colorful creations enable your little loved one to dress up for change just by walking down the street. Match with your outfit or just make the day a little greener – zero waste, lots of love.


Perhaps one of the only criticisms that could be levelled at a Volkswagen is that with so many on the road, they don't always stand out. Thankfully Leavens Volkswagen has the solution! Genuine VW Accessories not only increase the value of your sedan, wagon, or SUV, but also add some flash and pizzaz to help you stand out from the crowd.
Our Parts & Accessories section in London, ON offers a huge selection of genuine Volkswagen accessories to choose from. Plus, they're all available at bargain prices, so you won't break the bank accessorizing your V-Dub!
Everyone loves a comfortable car, that's why Leavens Volkswagen offers you a wide range of products designed to keep your Volkswagen shiny and clean. Rubberized floor mats keep your pride-and-joy clean from slush and snow you might track into the cabin, while air deflectors keep your interior cool and calm even with the windows down.
If you live an active lifestyle, you know that carrying your skis or bikes inside your Volkswagen isn't very practical. Nobody likes sliding a dirty bike into their clean car after a hard day's biking – that's where authentic VW bike racks and ski boxes come into play! These practical accessories maximize passenger and cargo space by letting you haul your stuff above your VW.
Whether it's a sturdy pair of metal winter rims or polished alloy wheels to give your Volkswagen some extra visual flair, Leavens Volkswagen's Parts & Accessories section has it all! Our wheels are not only built to the same high quality as your originals wheels, but are offered in various sizes to suit your personal sense of style.
If you want to get really serious about making your VW stand out, then Volkswagen's sport and design items are for you! These purely ascetic parts really make your vehicle stand out from the crowd. From aluminum pedals to kick plates, spoilers to exhaust tips, body kits to sport suspension, it's all here to make your V-Dub truly one-of-a-kind!
VW for Business: The Right Volkswagen for the Job!


text:
Home Food COVID: There are also delays in appointments for rapid tests in pharmacies in the Metropolis
COVID: There are also delays in appointments for rapid tests in pharmacies in the Metropolis
Food kin_wpadmin	· January 13, 2022 · 0 Comment
Given the recent rise in COVID-19 infections, not only in the state system are people interested in getting tested for the virus they must wait hours, and even days, to make an appointment or to be able to apply it, also in the various pharmacies of the metropolis that have the service there is a delay for it.
An example is the pharmacies with the trade name Comercializadora Farmacéutica De Chiapas SA De CV, which in Jalisco have carried out virus detection tests using antigens since 2020.
To go for a test at one of its 17 authorized branches, people must make an appointment on its website, however, in most of them you have to wait at least two days to schedule.
For example, if the platform is accessed today in at least 11 of its branches There is only availability until next Saturday 15th or Monday 17th of January.
In the pharmacy with the name Farmacias Guadalajara SA de CV, the doctors on duty distribute tokens to be able to carry out the antigen test in an orderly manner and without crowds, however interested persons must arrive early in order to catch a shiftOtherwise, they must return the next day to repeat the procedure.
According to one of the doctors in these types of establishments, what is happening is that there are currently very few COVID-19 detection tests in the private system, which is why they have set aside a certain number of daily tests to be able to deal with the fourth wave of cases, until suppliers, mostly from the United States, return to producing and shipping tests at the rate of the second wave of infections recorded between December 2020 and February 2021.
Yesterday this media outlet announced that in the free COVID-19 testing module of the Zapopan Centro Station, which is part of the Radar Jalisco strategy, there were people who, when they went one day and did not obtain a record for the intake, they had to return in days after forming from before 7:00 a.m. to get a turn.
Meanwhile, to access a test in one of the Cruz Verde modules in Guadalajara and Tlajomulco, you must make an appointment on line 3338-233220, which, due to demand, has been saturated in recent days.
Although it is not a pharmacy, the Salud Digna laboratory, where it is also possible to apply a rapid COVID detection test, also shows appointment saturation.
For example, at its Américas, San Juan, Tetlán and Zapopan Centro branches, as of today, Thursday, there are no more appointments available nor have more days of the month been enabled for scheduling, while at its bypass branch, until the closing of this note, there was only availability next Sunday.
Reference-www.informador.mx


Because everyday should be filled with laughter, joy, tears, and a sense of fulfillment.
There's a cool restaurant in Shanghai called the Fat Cow. They serve delicious burgers and sweet potato fries that are out of this world! It's a really cool atmosphere with a western type of vibe. I don't mean western as in cowboys and Indian's. I mean western vibe as in North America type of atmosphere and food. Okay, the food is delicious!
Now, as you may or may not know, I'm a little on the big and beautiful side. Sitting in the restaurant facing the Fat Cow sign and putting my margarita on the Fat Cow coaster is way too loud. The whole place is screaming for me to eat a freaking salad. I seriously feel self-conscious ordering a fat juicy guacamole burger with sweet potato fries when every time I blink I see, "Fat Cow".
I hope you see the humor in my post as I'm chuckling writing it. I mean no disrespect. Enjoy!
This entry was posted in Blogging, China and tagged Big and Beautiful, Dining, Family, Postaday, Restaurant, Traveling, Weight Issues by Still Times. Bookmark the permalink.
It sure is. I had someone take a picture of me by the sign. Umm no, decided it wasn't so funny after all. ha ha… I will say the food is delicious! Thank you for your comment. Have a fabulous evening!


Some futuristic Gel Lyte Vs.
Asics has decided to do away with stitches on its latest version of the Asics Gel Lyte V, opting instead to laser in perforations and details on the upper.
OK, so the shoes aren't entirely without stitches, but these versions do drastically cut down on them. The Asics Gel Lyte III has been dressing up in these lasered looks for a while now (which makes sense as it's the flagship retro runner from Asics) but the brand is now prepared to extend the treatment to other models.
Look for these updated Asics offerings to launch this weekend at retailers like Hanon.


text:
// Copyright 1998-2015 Epic Games, Inc. All Rights Reserved.

/*=============================================================================
	CompositionLighting.h: The center for all deferred lighting activities.
=============================================================================*/

#pragma once

#include "PostProcess/RenderingCompositionGraph.h"

/**
 * The center for all screen space processing activities (e.g. G-buffer manipulation, lighting).
 */
class FCompositionLighting
{
public:
	void ProcessBeforeBasePass(FRHICommandListImmediate& RHICmdList, FViewInfo& View);

	void ProcessAfterBasePass(FRHICommandListImmediate& RHICmdList,  FViewInfo& View);

	void ProcessLpvIndirect(FRHICommandListImmediate& RHICmdList, FViewInfo& View);

	void ProcessAfterLighting(FRHICommandListImmediate& RHICmdList, FViewInfo& View);
};

/** The global used for deferred lighting. */
extern FCompositionLighting GCompositionLighting;


text:
Switching Attorneys
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Working Hard for the Working Class
We devote all our resources to getting the best possible result. Contact us today to start your FREE case evaluation.
Lawrence & Associates > Bankruptcy > Creditor Harassment
Northern Kentucky Creditor Harassment Attorney
Lawrence & Associates can protect you from abusive and threatening creditors. Creditors are notorious for using threats, intimidation tactics and false information in order to scare debtors into making payments. The truth is, regardless of your ability to pay, or what a creditor may claim, there are certain actions they cannot legally take.
When you know the facts, you are in a better position to make decisions about your financial future and stop the abuse. According to the Fair Debt Collection Practices Act, creditors are prohibited from "abusive, deceptive and unfair debt collection practices." If a creditor continues to violate these laws and harass you and your family, you may be able to bring a claim against them and sue for financial damages. Contact our Northern Kentucky creditor harassment lawyers at (513) 351-5997 to get started.
Experienced Creditor Harassment Attorneys
Lawrence & Associates have handled creditor harassment cases in the past. Lawrence & Associates will work to build a strong and successful case for you against creditors that are harassing you.
The truth about debt collection attempts is that:
Creditors CANNOT call you at work once you have asked them to stop
Creditors CANNOT call you excessively or at unreasonable times
Creditors CANNOT call your family members and reveal the alleged debt
Creditors CANNOT intimidate you by providing false and misleading information
Creditors CANNOT have you arrested
Creditors CANNOT use vulgar or abusive language
Creditors CAN file a lawsuit to have a lien placed on your home
Creditors CAN seek to repossess your automobile
Creditors CAN attempt to garnish your wages
Creditors are legally obligated to cease all contact and collection attempts once you have filed for bankruptcy. If they do not, you have the right to sue them.
Contact a Creditor Harassment Lawyer
If you are being harassed by creditors, contact the Northern Kentucky bankruptcy attorneys of Lawrence & Associates for the help you need to put an end to it. Call (513) 351-5997 or contact us online.
A man was injured when a piece of construction equipment collided with his vehicle and crushed him.
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A man developed a rare nerve condition due to his employment, which made it impossible for him to use one arm.
A man was a passenger in a rental car when it spun out of control and killed him.
A barge worker (Jones Act Seaman) was climbing down a ladder from an empty to a loaded barge when the improperly secured ladder collapsed. The worker's head injury which caused...
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text:
Спермидинът е полиаминов биогенен амин с емпирична химична формула C7H19N3. Намира се в рибозомите и живите тъкани. Има различни функции в обмяната на веществата в организмите. Първоначално е бил изолиран от сперма.

Функция
Полиамините като спермидина са поликатионни алипатни амини. Имат различни функции. Много са важни за преживяването на клетките.

Спермидинът и сперминът имат силно основен характер (рН на спермата >7) и вероятно стимулират движението на сперматозоидите.

Спермидин синтаза (СПДС) катализира образуването на спермидина от путресцин. Спермидина е прекурсор за по-нататъшно полиамини, като спермин и неговите структурни изомери тероспермин.

Спермидина синхронизира множество биологични процеси (например Ca2+, Na+, K+ -АТФаза), като по този начин поддържа на мембранния капацитет и контролира вътреклетъчния обем и рН. Спермидинът регулира биологичните процеси, като например навлизането на Са2+ поради глутаматовия N-метил-d-аспартат рецептор (NMDA-рецепторите), който е свързан със синтеза на азотен оксид (азотен оксид) и цГМФ/ПКГ-овия път за активиране и намаляване на Na+,K+-АТФаза в синаптосомиге в кората на главния мозък.

Спермидина е агенти за дълголетие при бозайниците поради различни механизми на действие, които едва сега започват да бъдат разбират. Автофагия е основният механизъм на молекулярно ниво, но има доказателства и за други механизми, включително намаляване на възпалението, липидния метаболизъм и регулация на клетъчния растеж, пролиферация и смърт.

Спермидина, както е известно, регулира растежа на растенията. Инвитро подпомага процеса на транскрибиране на РНК, а също и инхибиране на NOS (не знам какво е?). Освен това, спермидина е прекурсор на други полиамини, като спермин и термоспермин, някои от които допринасят за толерантността към суша и засоленности на почвата в растенията.

Спермидинът е тестван и е открит, че стимулира растежа на косата. Спермидинът също се оказва, че "активира изразяване на кератинами К15 и К19 в епителните стволови клетки, както и дозозависимо на домулира К15 промоторната активност ин ситу., както и колония на ефективността на формиране, разпространение и К15 израз изолиран човек К15-протеин gfp+ клетки в епруветка." (преводът може да се подобри от някой който го разбира)

Биохимични действия
Известни действия на спермидина включват:
 Инхибирането невронния синтез на азотен оксид (nNOs)
 Свързва и преципитира ДНК
 Полиаминов регулатор на растежа на растенията

Хранителни източници
Добри хранителни източници на спермидина са отлежалото сирене, гъби, соеви продукти, фасул, царевица и пълнозърнести храни.

Забележка – съдържанието на спермидина варира в зависимост от източника и възрастта. Виж цитатите за подробности.

В тъканта ендосперма на зърата се съдържа повечето спермидина. Едни от най-известните зърнени култури, хранителни източници на протеини от пшеничен зародиш, който съдържат около 243 мг/кг спермидин.

Функции
 Спермидина можат да се използва при електропорация при прехвърляне на ДНК в клетката под електрически импулс. Може да се използва за почистване на ДНК-свързани протеини.
 Спермидина заедно с калциев хлорид се използва, за утаяване на ДНК на микроснаряди за бомбардировки с генни оръдия.
 Има данни, че спермидина намалява стареенето при мая, мухи, червеи и човешки имунни клетки при индукция аутофагоцитоза. Tirupati Pichiah и др., предложи, че спермидина може да бъде полезна за лечение на захарен диабет тип 2.
 Спермидина обикновено се използва за инвитро молекулярно-биологични реакции, в частност "инвитро" транскрипция на Фагова РНК полимераза, "инвитро" транскрипция на човешка РНК полимераза II ("инвитро" транскрипция на РНК-полимераза, и в инвитро транслация.

Вижте също
Други полиаминиː
 Путресцин
 Кадаверин
 Спермин

Източници

Външни препратки
 Лист За Безопасност

Амини


All drugs listed will be stored in the Emergency Department to ensure speedy provision of antidotes when required. Additional stocks will be kept in the Pharmacy Department.
A file has been compiled which contains comprehensive information on antidotes. A list of the location of all antidotes is contained in this file. The location in both the emergency department and the pharmacy are on this list.
The drugs will be stored in the antidote press in the resuscitation room.
Fridge items are kept in the resuscitation room fridge.
Several commonly used items, which are also used as antidotes will be stored as stock drugs in the drug cupboards in Resusc and Clean Utility room.
The emergency department Pharmaceutical technician will top-up the drugs twice-weekly Monday and Thursday to ensure the stock is available and to check expiry dates. It is the responsibility of the staff in the emergency department to reorder items that have been used immediately.
The antidote press in the pharmacy is under the bench on the left hand side of the dispensary and is clearly marked.
Stored in antidote press in Resuc.
Content by Pharmacy Dept. CUH, Dr Íomhar O' Sullivan 04/09/2005. Reviewed by Dr ÍOS 13/05/2007. Reviewed by Fiona Ahern 11/03/2008, 22/03/17.


text:
Guest writer Nordic Green to Scale for Countries, 2018
Nordic Green to Scale for Countries, 2018
Kuvaaja: Elina Salonen
Molok: Mutual trust between hunters leads to profitable business in Namibia
The Honorary Consul of Namibia, Timo Palander, helped Molok, a company that produces deep collection waste containers, take its first steps in Africa. He believes that finding trust between people is the most important element when cementing business partnerships.
Author's profile page: Esa Salminen
Esa Salminen is a journalist and writer who specialises in international topics. In autumn 2018, he and journalist Pasi Nokelainen will be publishing a non-fiction book called Afrikan valloittajat (Conquering Africa), which tells the story of Finnish entrepreneurs in Africa.
A beautiful log house stands by a lake at the end of a forest road. It's large and stylish, not just a little cottage but a house meant for year-round living. The scene is like something out of an idyllic Finnish movie. A lakefront sauna is visible from the window and a flag is flying proudly.
But this flag is more colourful than the blue and white of Finland. The art on the walls and the sign on the door tell visitors that this is no ordinary holiday home. This is the honorary consulate of Namibia, which is located in Lempäälä in the Pirkanmaa region.
The consulate moved from a shopping centre in Lempäälä to this lakeside setting when the owner, Honorary Consul Timo Palander, retired recently.
Municipal co-operation creates business
Palander's work has involved developing chambers of commerce and business life in Namibia. One of these projects opened the door to Africa for the Pirkanmaa-based company Molok.
A co-operation project had assessed the environmental activities of Namibian municipalities. The report was followed by discussion about whether Finland had any special expertise that could be jointly developed in Namibia. A light went on: Pirkanmaa was home to waste management and circular economy innovator Molok, whose deep collection containers were already being used in nearly every Finnish town. Molok's five cubic metre waste containers are 60 per cent underground and, at least in Finland, have been a money-saving investment for local authorities. Namibians might be interested in this!
After some enquiries, Molok expressed an interest in the idea. An exceptionally good family-owned waste management company called Rent-A-Drum had been identified in Namibia, and they seemed enthusiastic about investigating in opportunities to use Finnish technology and expertise in Namibia.
The breakthrough happened at an exhibition held in conjunction with the annual congress of the Association for Local Authorities in Namibia. Molok's stand had a conspicuous presence at the exhibition.
"I think it received the award for best international stand," recalls Palander. The company attracted interest among local ministers and other influential people.
This led to discussions with a few Namibian cities and Rent-A-Drum representatives about learning more about Finnish waste management and Molok.
"The critical point was when the cities realised that the Finnish technology offered something new – something that could provide cost effectiveness and ecological benefits," says Palander.
Another decisive factor was the fact that the people behind these companies understood each other. Palander believes that finding trust and understanding may be the one of the most difficult issues for Finnish companies doing business in Africa.
Growing friendship between hunters
If there's something that bothers Africans, it's the superior attitude occasionally displayed by Europeans. People in Africa still remember colonialism well. Although Finland didn't have any colonies, many in Finland sometimes make the mistake of overlooking this aspect of history.
However, Rent-A-Drum and Molok found an equal partnership – after a bit of nurturing by Palander.
"When I studied international marketing at Helsinki School of Economics in the 1970s, a professor said that if you're seriously considering international jobs you have to play tennis or golf," says Palander, as he pours some more tea.
"That was great advice. People need a social context in order to build mutual understanding and trust."
The CEOs of Molok and Rent-A-Drum found common ground through an interest in hunting rifles rather than the tennis court. Both of them are enthusiastic hunters. They were soon tracking antelope on the land around the holiday home of Rent-A-Drum's CEO, who, as far as we know, later became the first Namibian to bring down a Finnish elk.
"Building trust starts with the little things, like sitting around a campfire and grilling sausages," says Palander.
The chaos and unavoidable challenges faced in a new country are also easier to overcome together, as friends.
The partners discussed the possibility of exporting Molok's containers to Namibia. However, it soon became clear that the competitive position would be better if the products were at least partly manufactured in Namibia. A local brand would be stronger, could provide benefits in competitive bidding for local public-sector contracts and products that were at least partly local would be treated more favourably by the Namibian customs and taxation system.
The local element would also be beneficial if operations expanded to other parts of Africa with help from the Southern African Customs Union.
"Namibia only has a population of 2.5 million, but it can be a gateway to southern Africa," says Palander.
Finnpartnership provided support for the studies and eventually the companies represented by these hunters decided to produce the Molok containers in Namibia. Now they are exported from there to other countries in southern Africa.
Have some more.
Infographics of Nordic Green to Scale for Countries: Africa
Infographics of Nordic Green to Scale for Countries: Europe
International study: Nordic climate solutions have large potential in Poland
International study: Nordic climate solutions provide multiple benefits to people in Kenya
Technical report: Nordic Green to Scale for countries / Africa
Nordic green to scale for countries: Africa (handout)
Technical report: Nordic Green to Scale for Countries / Europe
All Green to Scale Materials
New study: Nordic climate solutions have large potential in Ukraine
Нове дослідження: скандинавські кліматичні рішення мають великий потенціал в Україні
Nordenen: Upscaling ten climate solutions
Nordic Green to Scale for countries: Europe (handout)
Nordic Green to Scale for countries (edited report Europe)
Nordic Green to Scale for Countries
The next phase of Green to Scale zooms in on country-specific policy recommendations.
Human activity contributes to climate change, and the consequences are serious. Curbing global warming requires a drastic reduction in emissions – right now.
The way we live, travel, eat and do business is undergoing a radical change. The new everyday life will be based on using services instead of owning things.


Even now, in the days of digital downloads and Spotify streaming, there is really nothing better than good album art. And if you can find beautiful, dark, surreal art on a metal album, all the better, right?
John Dyer Baizley and Marald van Haasteren worked together to make the artwork for Purple, the latest album by Baizley's band Baroness, and now, working in conjunction with screenprinting powerhouse Burlesque of North America, the two are bringing their drawings, paintings, and prints to town for a show at CO Exhibitions.
RW: John, you are based in Philadelphia, and Marald is based in the Netherlands. How did you all end up having an art show here in Minneapolis? What is your connection to Burlesque?
John: I have been printing my work exclusively through Burlesque for about a decade now; I consider them the best screenprinters on the planet and a far more creative enterprise than any of the other print shops I've had experiences with throughout my career. They are more concerned with cutting edge techniques and artistic presentation than most other screenprinters, who seem focused primarily on clean technique and sleek presentation. Occasionally at Burlesque, we end up creating prints that require spontaneity and expressiveness, which is an atypical quality for a screenprint (and screenprinter) to have. They have struck a balance between beautifully executed printing, and playful, creative presentation. Marald and I have been friends for quite a long time now, having met and maintained a relationship through our mutual involvement in the music scene. I have admired his work for many, many years, and "Desperation Burns" is both a showcase of the artwork that the two of us made for the Baroness album Purple and an attempt that I'd like to make to showcase Marald's work to an American audience. I spend so much time here in Minneapolis each year; CO Exhibitions was the natural choice for this event. It also allows us to create a number of prints of Marald's work, and to hang his originals, which I know he is incredibly excited to do.
RW: "Desperation Burns" is based around the artwork you both created for the latest Baroness album, Purple, and will include brand new work you made together here at Burlesque. Your styles are similar but definitely distinct, each bringing a different kind of stylization to your surreal, macabre drawings. Can you describe your collaborative process for this show? Is it like "I'm over here, you're over there" or are you working closely together on some new pieces?
John: We worked as closely as possible on all the images for this show, thanks to an easy Internet connectivity, and furthered by the fact that I tour through Netherlands quite frequently. We've been sending our drawings back and forth for the past couple of years, and we work together in a surprisingly seamless way. For the collaborative work we're doing, we planned the main ideas ahead of time, made a few reference studies, and have been working simultaneously all week, late into the night. We have a great rapport so, despite the intense labor, we are having a blast.
RW: What do you both see as the biggest influences on your work? Is it other artists, the music itself, life experiences? Marald, some of your drawings of skulls remind me a lot of old Dutch still lifes in their tone and detail. Is that a conscious reference, or have you kind of arrived at skulls mostly because of metal imagery?
John: Life influences affect my art as much and more than any particular artist, art or music, so deeply that I'm beginning to think there's very little separation between my art and my life. This may also be a result of the fact that I simply never stop making things. There are no breaks, no holidays, and very little sleep. I try to absorb the great scope of life's experience (the good, bad and UGLY), and express myself through my art and music.
Marald: I think there's a bit of both, but there has recently been a shift in my work that leads me to move away from imagery that is too overtly "metal" and move towards the classical imagery that I was initially drawn to in my youth.
RW: John, your work is almost like a weird combination of Frank Frazetta and Frida Kahlo, with these stylized nudes shrouded in all of this bizarre symbology and narrative. Are these symbols and narratives fully fleshed out in your head? For instance, are the four women on the cover of Purple representative of different personalities or characters for you?
John: That's a tricky question. Yes, in many ways the symbology is distinct, but more importantly, I consider them archetypes, and I let my subconscious work out themes through them. The literal imagery that I use is almost insignificant; they are things I simply enjoy drawing on one level. However, I believe that the sum total of all these visual metaphors, symbols, and mixed mythologies creates a narrative or concept that I don't need to articulate or really understand right now. In time, it will unfold itself to me, but I do a tremendous amount of research before I ever make a single line or brushstroke.
RW: I'm also impressed with how deliberately feminine Baroness's artwork seems to be, even down to the band name, of course. Skulls and naked women are nothing new to the world of punk and metal music, but this artwork has a delicacy and a temperament far removed from the shock and exploitation most people might expect from the metal scene. As a male artist, do you see it as a challenge to balance the use of naked women against the history of sexual objectification, or are you simply drawing from the heart and this is what comes out?
John: Yes, I'd like to think that through Baroness, and our artwork, we could offer an alternative to the expected lexicon of music-based imagery. There is enough machismo based, sexually objectifying, and frankly idiotic images out there; I think life, art and music is better than that, and we have something bigger to tackle, and potentially the means to do so through the band. But, as always, I demand a challenge, both for the viewer/listener/audience and myself.
RW: What can we expect at this show that we haven't seen from either of you before?
John: Something enormous in scale, and something that neither one of us could have done without the help and guidance of the other. It has been a surprise as we've created it; we hope our excitement and inspiration translates to those in attendance.
Desperation Burns: The Art of Purple opens Saturday, February 6th 7PM - 10PM at CO Exhibitions in Northeast Minneapolis. The exhibition will be on view through March 4th.
Buy Baroness' latest album Purple on Amazon to get ready for the show.


text:
19 Hottest Fictional Characters From Literature, Because Every Reader Has A Book Boyfriend Or Girlfriend
By Emma Oulton
Reading is so great because gives us a chance to expand our minds, learn about other experiences, visit other worlds ... and fantasize about hot fictional characters. The wonderful thing about reading a book is that you can project your own fantasy on to the characters you meet; all you need is a vague description of their general hotness, and the rest is between you and your wildest dreams. No matter how dreary your Monday morning commute is — when you whip out your battered old copy of Pride and Prejudice, suddenly you're having a steamy train ride with Mr. Darcy and everything else fades away.
And sure, the film and TV adaptations do a good job. Colin Firth in a wet shirt is the stuff dreams are made of, and I will never confess to how many times I've rewatched that scene. (It's in the high double figures, and that's all you need to know.) But in the book, Mr. Darcy can be even hotter than Colin Firth. I know, I know; that doesn't seem possible — but that's the whole point. In the book, he doesn't have to fit into any humanly possible depiction of a man; your imagination is the limit.
So here are 19 of the hottest fictional characters you will ever find — and they're all from books.
1. Mr. Darcy from 'Pride and Prejudice' by Jane Austen
Let's just start with this one, because it's a truth universally acknowledged that Mr. Darcy is the sexiest character ever to exist.
2. Emma Woodhouse from 'Emma' by Jane Austen
Right from the first line, Emma Woodhouse is described as "handsome, clever, and rich." Handsome's the key word here, but I'm not gonna lie: the other adjectives definitely add to her general hotness.
3. Laurie from 'Little Women' by Louisa May Alcott
Laurie is the ultimate boy next door. Growing up, I always dreamed about falling in love with a hot neighbor, and Little Women was a large part of the inspiration for that dream.
4. Tom Riddle from the Harry Potter series by J.K. Rowling
OK, so there's the minor detail that he's the most evil person in the Wizarding World — but aside from that, Tom Riddle is kind of a babe, right?
5. Shug from 'The Color Purple' by Alice Walker
Shug is the sexy jazz singer who finally awakens Celie's lust — and we all fall in love with her just as hard as Celie does.
6. Edward/Jacob from the Twilight series by Stephenie Meyer
It's far too dangerous to pick between this sexy pair, as they both have equally devoted fans — so they're just going to have to share this spot on the list. (For the record, I'm on #TeamJacob.)
7. T'Challa from Marvel's 'Black Panther'
T'Challa is super-handsome, strong, brainy — and he's the king of a whole nation. Yum.
8. Lisbeth Salander from the Millennium trilogy by Stieg Larsson
Lisbeth Salander is the totally badass heroine that everyone's completely terrified of, but would also love to date.
9. Mr. Rochester from 'Jane Eyre' by Charlotte Bronte
Mr. Rochester might not be handsome, but he's brooding, rugged, and passionate — and if you forget that he's got a wife locked in the attic, he's also a very caring guy. Reader, I'd like to marry him.
10. Adam from 'Shatter Me' by Tahereh Mafi
Adam has loved Juliette since they were eight years old — and he's described as alarmingly handsome with sexy tattoos. Yes, please.
11. Bill Weasley from the Harry Potter series by J.K. Rowling
I've got a soft spot for all the sexy ginger Weasleys, but Bill's long ponytail and earring bump him to the top of the pile.
12. Fleur Delacour from the Harry Potter series by J.K. Rowling
And of course, I couldn't mention Bill Weasley without mentioning his gorgeous wife Fleur Delacour. Boy, what a beautiful family.
13. Christian Grey from 'Fifty Shades of Grey' by E.L. James
Sure, he's a little controlling and creepy — but Christian Grey and his "playroom" sold record-breaking numbers of books, so I guess he is pretty hot.
14. Jesse de Silva from the Mediator series by Meg Cabot
Jesse de Silva is the 19th-century ghost that haunts Suze's bedroom — and I'd be happy for him to haunt my bedroom.
15. Rhysand from the A Court of Thorns and Roses series by Sarah J. Maas
Rhysand is a super hot and powerful faerie, whose seemingly aloof coldness is just a cover for his *deep feelings*. Swoon.
16. Jace from The Mortal Instruments trilogy by Cassandra Clare
Jace is another of those tough-on-the-outside-loving-on-the-inside book boyfriends that we just can't resist. On the surface, he's arrogant and rude — but when he's around Clary, he just can't keep his true emotions in check.
17. Areida from 'Ella Enchanted' by Gail Carson Levine
Areida's lovely lilting accent might make the girls at finishing school laugh, but it also makes her sound super-desirable — especially when paired with the descriptions of her sexy singing voice.
18. Gilbert Blythe from 'Anne of Green Gables' by L.M. Montgomery
Gilbert had a lot of growing up to do, and he deserved everything he got when Anne smashed that slate on his head — but he loved Anne devotedly throughout the rest of the series, and left many a bookworm pining over him. Oh, and he's tall and handsome.
19. Helen of Troy from 'The Iliad' by Homer
Known as "the face that launched a thousand ships," as her incredible beauty sparked the decade-long Trojan War, Helen of Troy has got to be the hottest literary character of all time.


Robots will eventually replace human workers in the retail industry, the chief executive of Chinese e-commerce company JD.com predicted on Tuesday.
China's second-largest e-commerce business has built up an extensive logistics network and is investing heavily in drones, robotics and automation.
JD.com has expanded heavily into luxury goods, apparel and offline retail over the past year in an effort to tap new consumers, echoing similar efforts by bigger rival Alibaba Group Holding.
"We have to make a lot of innovation every day and never stop ... Reduce cost and improve customer experience. That's all," Liu said of his business philosophy.
Liu also said that Western retailers were shielded somewhat from the sector's rapid pace of change by the loyalty of their customers, in contrast with China, where shoppers prefer to try something new and are more demanding in terms of delivery speed.


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Vermeer's hat: the seventeenth century and the dawn of the global world
Lecture: 21 March 2012
Vermeer's paintings captivate us with their beautifully rendered light and scenes of Dutch daily life, but these intimate views also offer unexpected glimpses of an increasingly interconnected world in the 17th century. Moving outward from Vermeer's home town of Delft to the Americas, Asia and back again to Europe, author Timothy Brook traces the complex global stories embodied in these masterpieces.
Formerly the Shaw Chair in Chinese at Oxford University, Professor Brook is now the Republic of China Chair at the University of British Columbia.
Made possible by the George Swinnerton Parker Memorial Lecture Fund.
This talk is held in conjunction with A Material World: The Art and Culture of Global Connections symposium on March 22.
7-8 pm, Morse Auditorium
Reservations by March 20
Members and A Material World symposium registrants $7, nonmembers $10


WARNING: This video contains violence that may not be suitable for all viewers.
The video below was taken by a resident in the 600 block of Inca Street on Sunday afternoon during a standoff between Denver police and a barricaded suspect. Two officers were shot during the standoff, which lasted several hours before a suspect was taken into custody. Another SWAT officer was injured in a traffic crash on the way to the scene.


To all a good story! You made me giggle.
Love love love this story. You had me ho-ho-ho-ing all the way. Captivating storytelling Grumpy!
I expect we'll see Santa in AA sooner or later, but then we'll never know, will we?
What fun! Dang those escapee reindeer. He's in the mix now.
I saw an image on Facebook (can't find it now) of the aftermath of a mid-air collision between Santa's sleigh and an flying saucer. They're both crashed in the snow and police are taking statements from both St. Nick and the alien, though it looks like the alien is being taken into custody. That's the first thing I thought of as I read your story. Maybe I should have written that instead.
Haha! I do hope the wordpressers got some good prompts. But the burning question for me is: did Santa get his ale eventually? That's really important. 😉 Fun story!
What a fun take on the prompt. Very cheeky! Loved it – smiled all the way through!


Nearly a year in the making, Django 1.3 includes quite a few new features and plenty of bug fixes and improvements to existing features. These release notes cover the new features in 1.3, as well as some backwards-incompatible changes you'll want to be aware of when upgrading from Django 1.2 or older versions.
A framework for writing class-based views.
Built-in support for using Python's logging facilities.
Contrib support for easy handling of static files.
Django's testing framework now supports (and ships with a copy of) the unittest2 library.
Wherever possible, of course, new features are introduced in a backwards-compatible manner per our API stability policy policy. As a result of this policy, Django 1.3 begins the deprecation process for some features.
The release of Django 1.2 was notable for having the first shift in Django's Python compatibility policy; prior to Django 1.2, Django supported any 2.x version of Python from 2.3 up. As of Django 1.2, the minimum requirement was raised to Python 2.4.
Django 1.3 continues to support Python 2.4, but will be the final Django release series to do so; beginning with Django 1.4, the minimum supported Python version will be 2.5. A document outlining our full timeline for deprecating Python 2.x and moving to Python 3.x will be published shortly after the release of Django 1.3.
Django 1.3 adds a framework that allows you to use a class as a view. This means you can compose a view out of a collection of methods that can be subclassed and overridden to provide common views of data without having to write too much code.
Analogs of all the old function-based generic views have been provided, along with a completely generic view base class that can be used as the basis for reusable applications that can be easily extended.
See the documentation on class-based generic views for more details. There is also a document to help you convert your function-based generic views to class-based views.
Django 1.3 adds framework-level support for Python's logging module. This means you can now easily configure and control logging as part of your Django project. A number of logging handlers and logging calls have been added to Django's own code as well – most notably, the error emails sent on a HTTP 500 server error are now handled as a logging activity. See the documentation on Django's logging interface for more details.
In previous versions of Django, it was common to place static assets in MEDIA_ROOT along with user-uploaded files, and serve them both at MEDIA_URL. Part of the purpose of introducing the staticfiles app is to make it easier to keep static files separate from user-uploaded files. Static assets should now go in static/ subdirectories of your apps or in other static assets directories listed in STATICFILES_DIRS, and will be served at STATIC_URL.
See the reference documentation of the app for more details or learn how to manage static files.
Python 2.7 introduced some major changes to the unittest library, adding some extremely useful features. To ensure that every Django project can benefit from these new features, Django ships with a copy of unittest2, a copy of the Python 2.7 unittest library, backported for Python 2.4 compatibility.
To access this library, Django provides the django.utils.unittest module alias. If you are using Python 2.7, or you have installed unittest2 locally, Django will map the alias to the installed version of the unittest library. Otherwise, Django will use its own bundled version of unittest2.
If you want to continue to use the base unittest library, you can – you just won't get any of the nice new unittest2 features.
ForeignKey and OneToOneField now accept an on_delete argument to customize behavior when the referenced object is deleted. Previously, deletes were always cascaded; available alternatives now include set null, set default, set to any value, protect, or do nothing.
For more information, see the on_delete documentation.
For translation strings with ambiguous meaning, you can now use the pgettext function to specify the context of the string.
And if you just want to add some information for translators, you can also add special translator comments in the source.
For more information, see Contextual markers and Comments for translators.
The with tag now allows you to define multiple context variables in a single with block.
The load tag now accepts a from argument, allowing you to load a single tag or filter from a library.
It can sometimes be beneficial to allow decorators or middleware to modify a response after it has been constructed by the view. For example, you may want to change the template that is used, or put additional data into the context.
However, you can't (easily) modify the content of a basic HttpResponse after it has been constructed. To overcome this limitation, Django 1.3 adds a new TemplateResponse class. Unlike basic HttpResponse objects, TemplateResponse objects retain the details of the template and context that was provided by the view to compute the response. The final output of the response is not computed until it is needed, later in the response process.
For more details, see the documentation on the TemplateResponse class.
Django 1.3 sees the introduction of several improvements to the Django's caching infrastructure.
Firstly, Django now supports multiple named caches. In the same way that Django 1.2 introduced support for multiple database connections, Django 1.3 allows you to use the new CACHES setting to define multiple named cache connections.
Secondly, versioning, site-wide prefixing and transformation have been added to the cache API.
Thirdly, cache key creation has been updated to take the request query string into account on GET requests.
Finally, support for pylibmc has been added to the memcached cache backend.
For more details, see the documentation on caching in Django.
If you provide a custom auth backend with supports_inactive_user set to True, an inactive User instance will check the backend for permissions. This is useful for further centralizing the permission handling. See the authentication docs for more details.
The GeoDjango test suite is now included when running the Django test suite with runtests.py when using spatial database backends.
Previously, the MEDIA_URL setting only required a trailing slash if it contained a suffix beyond the domain name.
A trailing slash is now required for MEDIA_URL and the new STATIC_URL setting as long as it is not blank. This ensures there is a consistent way to combine paths in templates.
Project settings which provide either of both settings without a trailing slash will now raise a PendingDeprecationWarning.
In Django 1.4 this same condition will raise DeprecationWarning, and in Django 1.5 will raise an ImproperlyConfigured exception.
Django 1.1 and 1.2 added lots of big ticket items to Django, like multiple-database support, model validation, and a session-based messages framework. However, this focus on big features came at the cost of lots of smaller features.
Improved tools for accessing and manipulating the current Site object in the sites framework.
A RequestFactory for mocking requests in tests.
A new test assertion – assertNumQueries() – making it easier to test the database activity associated with a view.
Support for lookups spanning relations in admin's list_filter.
mail_admins() and mail_managers() now support easily attaching HTML content to messages.
Error emails now include more of the detail and formatting of the debug server error page.
simple_tag() now accepts a takes_context argument, making it easier to write simple template tags that require access to template context.
A new render() shortcut – an alternative to django.shortcuts.render_to_response() providing a RequestContext by default.
Support for combining F expressions with timedelta values when retrieving or updating database values.
Prior to Django 1.2.5, Django's CSRF-prevention system exempted AJAX requests from CSRF verification; due to security issues reported to us, however, all requests are now subjected to CSRF verification. Consult the Django CSRF documentation for details on how to handle CSRF verification in AJAX requests.
Prior to Django 1.2.5, the Django administrative interface allowed filtering on any model field or relation – not just those specified in list_filter – via query string manipulation. Due to security issues reported to us, however, query string lookup arguments in the admin must be for fields or relations specified in list_filter or date_hierarchy.
In earlier Django versions, when a model instance containing a FileField was deleted, FileField took it upon itself to also delete the file from the backend storage. This opened the door to several data-loss scenarios, including rolled-back transactions and fields on different models referencing the same file. In Django 1.3, when a model is deleted the FileField's delete() method won't be called. If you need cleanup of orphaned files, you'll need to handle it yourself (for instance, with a custom management command that can be run manually or scheduled to run periodically via e.g. cron).
The PasswordInput form widget, intended for use with form fields which represent passwords, accepts a boolean keyword argument render_value indicating whether to send its data back to the browser when displaying a submitted form with errors. Prior to Django 1.3, this argument defaulted to True, meaning that the submitted password would be sent back to the browser as part of the form. Developers who wished to add a bit of additional security by excluding that value from the redisplayed form could instantiate a PasswordInput passing render_value=False .
Django 1.3 now includes a ClearableFileInput form widget in addition to FileInput. ClearableFileInput renders with a checkbox to clear the field's value (if the field has a value and is not required); FileInput provided no means for clearing an existing file from a FileField.
ClearableFileInput is now the default widget for a FileField, so existing forms including FileField without assigning a custom widget will need to account for the possible extra checkbox in the rendered form output.
Prior to Django 1.3, the database table used by the database backend for the sessions app had no index on the expire_date column. As a result, date-based queries on the session table – such as the query that is needed to purge old sessions – would be very slow if there were lots of sessions.
Django has historically provided (and enforced) a list of profanities. The comments app has enforced this list of profanities, preventing people from submitting comments that contained one of those profanities.
Unfortunately, the technique used to implement this profanities list was woefully naive, and prone to the Scunthorpe problem. Improving the built-in filter to fix this problem would require significant effort, and since natural language processing isn't the normal domain of a web framework, we have "fixed" the problem by making the list of prohibited words an empty list.
If you want to restore the old behavior, simply put a PROFANITIES_LIST setting in your settings file that includes the words that you want to prohibit (see the commit that implemented this change if you want to see the list of words that was historically prohibited). However, if avoiding profanities is important to you, you would be well advised to seek out a better, less naive approach to the problem.
Canada (ca) – The province "Newfoundland and Labrador" has had its province code updated to "NL", rather than the older "NF". In addition, the Yukon Territory has had its province code corrected to "YT", instead of "YK".
Indonesia (id) – The province "Nanggroe Aceh Darussalam (NAD)" has been removed from the province list in favor of the new official designation "Aceh (ACE)".
United States of America (us) – The list of "states" used by USStateField has expanded to include Armed Forces postal codes. This is backwards-incompatible if you were relying on USStateField not including them.
In Django 1.3 FormSet creation behavior is modified slightly. Historically the class didn't make a distinction between not being passed data and being passed empty dictionary. This was inconsistent with behavior in other parts of the framework. Starting with 1.3 if you pass in empty dictionary the FormSet will raise a ValidationError.
This has been resolved in Django 1.3 - the result in both cases will be u'Joe Bloggs'. Although the previous behavior was not useful for a template language designed for web designers, and was never deliberately supported, it is possible that some templates may be broken by this change.
Django provides a custom SQL hooks as a way to inject hand-crafted SQL into the database synchronization process. One of the possible uses for this custom SQL is to insert data into your database. If your custom SQL contains INSERT statements, those insertions will be performed every time your database is synchronized. This includes the synchronization of any test databases that are created when you run a test suite.
However, in the process of testing the Django 1.3, it was discovered that this feature has never completely worked as advertised. When using database backends that don't support transactions, or when using a TransactionTestCase, data that has been inserted using custom SQL will not be visible during the testing process.
Unfortunately, there was no way to rectify this problem without introducing a backwards incompatibility. Rather than leave SQL-inserted initial data in an uncertain state, Django now enforces the policy that data inserted by custom SQL will not be visible during testing.
This change only affects the testing process. You can still use custom SQL to load data into your production database as part of the syncdb process. If you require data to exist during test conditions, you should either insert it using test fixtures, or using the setUp() method of your test case.
Priorities of translations included with applications listed in the INSTALLED_APPS setting were changed. To provide a behavior consistent with other parts of Django that also use such setting (templates, etc.) now, when building the translation that will be made available, the apps listed first have higher precedence than the ones listed later.
Now it is possible to override the translations shipped with applications by using the LOCALE_PATHS setting whose translations have now higher precedence than the translations of INSTALLED_APPS applications. The relative priority among the values listed in this setting has also been modified so the paths listed first have higher precedence than the ones listed later.
The locale subdirectory of the directory containing the settings, that usually coincides with and is known as the project directory is being deprecated in this release as a source of translations. (the precedence of these translations is intermediate between applications and LOCALE_PATHS translations). See the corresponding deprecated features section of this document.
When using managed transactions – that is, anything but the default autocommit mode – it is important when a transaction is marked as "dirty". Dirty transactions are committed by the commit_on_success decorator or the django.middleware.transaction.TransactionMiddleware, and commit_manually forces them to be closed explicitly; clean transactions "get a pass", which means they are usually rolled back at the end of a request when the connection is closed.
Until Django 1.3, transactions were only marked dirty when Django was aware of a modifying operation performed in them; that is, either some model was saved, some bulk update or delete was performed, or the user explicitly called transaction.set_dirty(). In Django 1.3, a transaction is marked dirty when any database operation is performed.
Prior to Django 1.3, this would work without error. However, under Django 1.3, this will raise a TransactionManagementError because the read operation that retrieves the MyObject instance leaves the transaction in a dirty state.
Prior to Django 1.3, inactive users were able to request a password reset email and reset their password. In Django 1.3 inactive users will receive the same message as a nonexistent account.
The django.contrib.auth.views.password_reset() view now accepts a from_email parameter, which is passed to the password_reset_form's save() method as a keyword argument. If you are using this view with a custom password reset form, then you will need to ensure your form's save() method accepts this keyword argument.
Django 1.3 deprecates some features from earlier releases. These features are still supported, but will be gradually phased out over the next few release cycles.
Code taking advantage of any of the features below will raise a PendingDeprecationWarning in Django 1.3. This warning will be silent by default, but may be turned on using Python's warnings module, or by running Python with a -Wd or -Wall flag.
In Django 1.4, these warnings will become a DeprecationWarning, which is not silent. In Django 1.5 support for these features will be removed entirely.
For more details, see the documentation Django's release process and our deprecation timeline.
The mod_python library has not had a release since 2007 or a commit since 2008. The Apache Foundation board voted to remove mod_python from the set of active projects in its version control repositories, and its lead developer has shifted all of his efforts toward the lighter, slimmer, more stable, and more flexible mod_wsgi backend.
If you are currently using the mod_python request handler, you should redeploy your Django projects using another request handler. mod_wsgi is the request handler recommended by the Django project, but FastCGI is also supported. Support for mod_python deployment will be removed in Django 1.5.
Django's test client returns Response objects annotated with extra testing information. In Django versions prior to 1.3, this included a template attribute containing information about templates rendered in generating the response: either None, a single Template object, or a list of Template objects. This inconsistency in return values (sometimes a list, sometimes not) made the attribute difficult to work with.
In Django 1.3 the template attribute is deprecated in favor of a new templates attribute, which is always a list, even if it has only a single element or no elements.
As a result of the introduction of support for unittest2, the features of django.test.simple.DjangoTestRunner (including fail-fast and Ctrl-C test termination) have been made redundant. In view of this redundancy, DjangoTestRunner has been turned into an empty placeholder class, and will be removed entirely in Django 1.5.
However, due to an accident of history, the url and ssi are different. These tags use the second, quoteless syntax, but interpret the argument as a constant. This means it isn't possible to use a context variable as the target of a url and ssi tag.
The tags implementing the old behavior have been deprecated, and in Django 1.5, the old behavior will be replaced with the new behavior. To ensure compatibility with future versions of Django, existing templates should be modified to use the new future libraries and syntax.
In previous version the admin app defined login methods in multiple locations and ignored the almost identical implementation in the already used auth app. A side effect of this duplication was the missing adoption of the changes made in r12634 to support a broader set of characters for usernames.
This release refactors the admin's login mechanism to use a subclass of the AuthenticationForm instead of a manual form validation. The previously undocumented method 'django.contrib.admin.sites.AdminSite.display_login_form' has been removed in favor of a new login_form attribute.
Those commands have been deprecated. The flush and sqlflush commands can be used to delete everything. You can also use ALTER TABLE or DROP TABLE statements manually.
The function-based TEST_RUNNER previously used to execute the GeoDjango test suite, django.contrib.gis.tests.run_gis_tests, was deprecated for the class-based runner, django.contrib.gis.tests.GeoDjangoTestSuiteRunner.
Previously, calling transform() would silently do nothing when GDAL wasn't available. Now, a GEOSException is properly raised to indicate possible faulty application code. A warning is now raised if transform() is called when the SRID of the geometry is less than 0 or None.
Previously this field's clean() method accepted a second, gender, argument which allowed stronger validation checks to be made, however since this argument could never actually be passed from the Django form machinery it is now pending deprecation.
Previously, django.http exposed an undocumented CompatCookie class, which was a bugfix wrapper around the standard library SimpleCookie. As the fixes are moving upstream, this is now deprecated - you should use from django.http import SimpleCookie instead.
This release of Django starts the deprecation process for inclusion of translations located under the so-called project path in the translation building process performed at runtime. The LOCALE_PATHS setting can be used for the same task by adding the filesystem path to a locale directory containing project-level translations to the value of that setting.
The project path has always been a loosely defined concept (actually, the directory used for locating project-level translations is the directory containing the settings module) and there has been a shift in other parts of the framework to stop using it as a reference for location of assets at runtime.
Detection of the locale subdirectory tends to fail when the deployment scenario is more complex than the basic one. e.g. it fails when the settings module is a directory (ticket #10765).
/usr/lib/python2.6/gettext.py:49: ImportWarning: Not importing directory '/path/to/project/locale': missing __init__.py.
In Django 1.2, we began the process of changing the location of the auth context processor from django.core.context_processors to django.contrib.auth.context_processors. However, the PermWrapper support class was mistakenly omitted from that migration. In Django 1.3, the PermWrapper class has also been moved to django.contrib.auth.context_processors, along with the PermLookupDict support class. The new classes are functionally identical to their old versions; only the module location has changed.
When Django was first released, Django included an XMLField that performed automatic XML validation for any field input. However, this validation function hasn't been performed since the introduction of newforms, prior to the 1.0 release. As a result, XMLField as currently implemented is functionally indistinguishable from a simple TextField.
For this reason, Django 1.3 has fast-tracked the deprecation of XMLField – instead of a two-release deprecation, XMLField will be removed entirely in Django 1.4.
It's easy to update your code to accommodate this change – just replace all uses of XMLField with TextField, and remove the schema_path keyword argument (if it is specified).
Dutch Django Association donated to the Django Software Foundation to support Django development. Donate today!


When the time to retire finally comes, you may feel relieved or concerned – if you spent your whole life saving and preparing for retirement, it's time to relax and watch your years of planning unfold. If that's not the case, retirement may be slightly stressful as you decide how to make your funds last – with the help of Maier & Associates, we can help reduce this stress.
For a financially successful retirement, it is essential to know your retirement plan and benefits you are eligible to receive. There are a number of considerations including when you should start/begin your pension or Social Security benefits. You'll also want to consider if you should delay benefits to a later date and utilize your savings first for tax purposes and to build an enhanced fixed income payout. Further, we believe retirees need to know the amount of fixed income from pension and Social Security they will receive at retirement and when. Then compare that number to the actual retirement income need. In doing so, you should have insight to the amount of dollars you need to have saved. We believe not until this comparison is made should you make a decision on when to retire.
Maier & Associates Planning provides long-term strategic financial planning for retirees. We can help you learn what your retirement and investment options are, and help create a plan to help make your wealth last – long before the time to retire actually arrives.
When you carefully manage your assets, your savings are more likely to last you the duration of your retirement. Don't assume that you will be able to live on your investment portfolio and retirement account earnings for the rest of your life – you will probably have to start drawing on the principal at some point.
We know that it can be exciting to finally be retired, and tempting to spend too much too soon – especially at the beginning of your retirement. That is why it is so important to remember that if you reduce your principal too rapidly, you may not be able to earn enough on the existing principal to carry you through the later years. A good guideline is to make sure your annual withdrawal rate isn't greater than 4% to 6% of your portfolio – however, this percentage can vary from person to person depending on the length of your payout period and your portfolio's asset allocation.
By planning ahead, investing wisely, and spending thoughtfully, you increase the likelihood that your retirement will be a financially secure one. Maier & Associates Planning offers guidance through the various stages of retirement.


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Varèse Sarabande: THE FINAL GIRLS [2015] - Gregory James Jenkins
Varèse Sarabande will release the THE FINAL GIRLS – Original Motion Picture Soundtrack digitally on November 6 and on CD December 4, 2015. The album features original music by composer Gregory James Jenkins (GOLDIE AND BEAR).
"THE FINAL GIRLS was my first feature score and I'm super proud of it," said Jenkins. "In the film, our lead characters get sucked into an 80's slasher movie called Camp Bloodbath. One of the biggest challenges was trying to create a score that was heavily steeped in 1980's while still trying to bring something new to the table."
When Max (Taissa Farmiga) and her friends reluctantly attend a anniversary screening of Camp Bloodbath, the infamous '80s horror film that starred Max's late mother (Malin Akerman), they are mysteriously sucked into the silver screen. They soon realize they are trapped inside the cult classic movie and must team up with the fictional and ill-fated camp counselors, including Max's mom as the scream queen, to battle the film's machete-wielding killer. With the body count rising in scene after iconic scene, who will be the final girls left standing and live to escape this film? THE FINAL GIRLS is a genre-blending horror comedy also starring Adam DeVine, Thomas Middleditch, Alia Shawkat with Alexander Ludwig and Nina Dobrev.
Gregory James Jenkins is a composer and producer in Los Angeles, CA. After growing up near Detroit, MI he moved to Boston, MA to study music synthesis at the Berklee College of Music.
Over the past 8 years he's done the music for dozens of commercials, scored several short films, and has had his music featured in films such as THE LUCKY ONE and A VERY HAROLD AND KUMAR 3D CHRISTMAS. In 2014 he saw the release of the album Not a Trampolineby Rob Cantor, which he produced and mixed under his alias Gregtronic. THE FINAL GIRLS is his first feature length score. In addition to loving synthesizers, outer space, and his wife (Zabeth Russell), he is currently one of the composers for Disney's GOLDIE AND BEAR.
"This is not your typical film score, as it's mostly electronic based," Jenkins described. "Most of the score was me and my computer. A lot of analog synths were used. For the geeks out there here's a list: Roland SH-1000, Yamaha CS-15, Elektron Analog Keys, Korg Volca series, Moog Liberation, Dave Smith Prophet 08, Korg Poly-800. I also would like to point out the contributions of two amazing musicians. Chase Deso did all of the guitar work peppered throughout the score, and Jake Bartfield played cello, double bass and electric bass."
Stage 6 Films presents THE FINAL GIRLS now playing in theaters, On Demand, and on Digital HD! On Blu-Ray™ November 3, 2015. Varèse Sarabande will release the THE FINAL GIRLS – Original Motion Picture Soundtrack digitally on November 6 and on CD December 4, 2015.
Varese Sarabande | http://www.varesesarabande.com
Labels: Varese Sarabande


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