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Team Jeeva
Jeeva eClinical Platform
eConsent as a Service
ePRO as a Service
TRIALMAGNET
CRO Partnership Program
Patient Groups
Podcasts & TV Interviews
Removing Socioeconomic Barriers and Increasing Diversity in Clinical Trials Would Have a Positive Economic Impact
Between logistical burdens, distrust in the healthcare system, and lack of awareness and information in many non-English languages, key demographic groups like women, children, low-income households, and racial and ethnic minorities are effectively left out of clinical trials.
TYSONS CORNER, Va. (PRWEB)January 03, 2023
Clinical trials have a failure rate of 30% because they cannot meet their target patient enrollment, which is often caused by a lack of diversity in clinical trial candidates. This results in setbacks in 85% of clinical trials causing biopharmaceutical sponsors to lose $600K to $8M for each day a trial is delayed.(1) Limited representation and inclusion of a diverse population in clinical trials have far-reaching consequences by skewing clinical trial results, leading to poorer health outcomes and premature deaths among the U.S. population. Jeeva Informatics is the leading human-centric eClinical platform seeking to accelerate patient recruitment and retention by being champions of diversity, equity, and inclusion in clinical trials through decentralization and reducing socioeconomic barriers to healthcare.
"Recruitment for clinical trials is severely broken," explains Dr. Harsha Rajasimha, Founder and CEO of Jeeva Informatics. He notes, "Between logistical burdens, distrust in the healthcare system, and lack of awareness and information in many non-English languages, key demographic groups like women, children, low-income households, and racial and ethnic minorities are effectively left out of clinical trials." The Future Elderly Model developed by the USC Schaeffer Center found that if drug development using more representative clinical trials eliminated just 1% of these health disparities, it would result in significant gains for patients and society. The study further concluded that increased representation in clinical trials could save billions of dollars and improve the quality of life for millions of Americans.(2)
One out of four patients cites logistical burdens, such as access/cost of childcare, transportation, and loss of pay, as the primary reasons for not taking part in clinical trials. The vast majority of participants are Caucasian adult males from affluent backgrounds.(1) Patients with an annual household income of less than $50,000 have 32% lower odds of trial enrollment. Aside from financial challenges, other socioeconomic obstacles, such as a lack of insurance, limited job flexibility, and health illiteracy, contribute to a generalized apprehension regarding clinical trials.(3)
Regulatory agencies are now taking steps to encourage researchers to make diversity a focus. The FDA recently released its "Diversity Plans to Improve Enrollment of Participants from Underrepresented Racial and Ethnic Populations in Clinical Trials." In it, they recommend financial reimbursement or compensation for expenses incurred, language assistance for participants with limited English language proficiency, and clinical trial sponsor enrollment goals for underrepresented racial and ethnic participants.(4)
In addition to saving billions of dollars and improving the health of all American citizens, improving diversity helps build trust between the pharmaceutical industry and the public, which has long been a strained relationship. Biopharmaceutical companies are forming partnerships with local communities and patient advocacy groups, offering financial support, and providing more convenient trial locations to help improve access, spread awareness, and build trust among more diverse populations.(5)
A decentralized trial model helps meet patients where they live and utilizes local community leaders to earn participants' trust and make them feel more comfortable about the information. For Dr. Rajasimha, diversity has been a priority from day one. While regulatory bodies and researchers tout the benefits of diversity, the reality is harder to achieve and requires more time and resources. The traditional model of all in-person patient visits no longer works, and to achieve operational flexibility with reliable and accurate results, Dr. Rajasimha and his team developed the modular Jeeva™ eClinical Cloud by leveraging stakeholder inputs over the last few years. This human-centric and empathetic platform accelerates clinical research timelines over 3x faster.
With bi-directional communications, activity scheduling, eligibility screening, and remote touchless electronic informed consent, investigators can educate and enroll participants safely from their own mobile devices. Investigator teams can avoid repetitive tasks and save 70% of their time during enrollment. Dr. Rajasimha stresses, "It is imperative that, as an industry, we work to accelerate clinical trials to bring new medicines or vaccines to all patients, including historically underrepresented minorities, who need them, thus increasing the chances of survival. Our modular platform is fully scalable and facilitates diverse patient enrollment, engagement, retention, and evidence generation."
About Jeeva Informatics
The personal experience of losing a child born with a rare disease and a brother with a chronic disease became the springboard for Dr. Harsha Rajasimha to apply his years of postdoctoral training at NIH and FDA to accelerating therapies for rare and common conditions. He knew that technology in itself is not the limiting factor and that patient-centered design guided by stakeholder needs and regulatory requirements would guide their continuous learning digital platform. By digitizing and automating manual repetitive tasks and reducing the logistical burdens on patients and study teams by over 70%, Jeeva accelerates the process of bringing new medicines or vaccines to patients who need them by over 3x faster. The Virginia-based company's modular software-as-a-service platform is fully scalable and facilitates patient enrollment, engagement, and evidence generation in clinical trials on any browser-enabled mobile device. Visit https://jeevatrials.com/.
1. Frank Sasinowski, MPH. "Jeeva – Accelerate Clinical Research, Maximize Patient Diversity." Decentralized Clinical Research Software as a Service, jeevatrials.com/.
2. Goldman, Dana, et al. "Lack of Diversity in Clinical Trials Costs Billions of Dollars. Incentives Can Spur Innovation." USC Schaeffer, 30 Sept. 2022, healthpolicy.usc.edu/article/lack-of-diversity-in-clinical-trials-costs-billions-of-dollars-incentives-can-spur-innovation/.
3. Price, Kyla N., et al. "Facilitating Clinical Trials Participation of Low Socioeconomic Status Patients." Dermatology, Karger Publishers, 15 Dec. 2020, karger.com/Article/FullText/511889.
4. "FDA Guidance on Diversity Plans in Clinical Trials: What You Need to Know." Bass, Berry & Sims PLC, bassberry.com/news/diversity-plans-clinical-trials/.
5. "Achieving Clinical-Trial Diversity Requires Trust, Awareness, Access." Deloitte United States, 2.deloitte.com/us/en/blog/health-care-blog/2022/achieving-clinical-trial-diversity-requires-trust-awareness-access.html.
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Dr. Sweta Sneha
Dr. Sweta Sneha is the Founder and Executive Director of Healthcare Management & Informatics and Professor of Information Systems & Security at Kennesaw State University. A globally recognized expert with a passion towards equity and diversity, Sneha is a strategic leader with two decades of experience in technology and informatics. She is a recipient of Distinguished Service Award, KSU Collaboration Award, NCWIT RISE-IT Award, and WIT Honoree, WIT Finalist (2018, 2019, 2020, 2021, 2022). Dr. Sneha has published over 100 peer-reviewed research; authored a book on revolutionizing healthcare; delivered panel sessions, workshops, and keynotes; in addition to serving on several boards. Dr. Sneha serves as editorial steward and university ambassador for Blockchain in Healthcare Today; editorial board for Health Systems Journal; co-chairs Health IT at AMCIS, and HICSS. Her leadership has led to enhancing KSU's footprint on diversity and equity, STEAM education, and outreach. She has a PhD in Computer Information Systems from Georgia State University and a BS in Computer Science from University of Maryland. Prior to academia, she worked at PricewaterhouseCoopers in Management Consulting.


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redpajama_set_name: RedPajamaGithub


In reality, winter weddings are rather trendy! Not only do they tend to be cheaper as many venues and vendors offer discounted Winter rates, but they offer an incredibly magical and romantic backdrop for photos - the ice and snow shimmers and sparkles in the winter sun and reflects beautifully on the couple. Now, to actually enjoy a winter wonderland wedding, you have to be well prepared, and what better way to stay warm then in Ugg boots, a white faux fur coat, and Apple Cider? Alana and Dan's winter wedding at Ancaster Mill had all that, and much more!
Their winter wedding at Ancaster Mill was our first wedding of the year. While the ground was icy and covered in snow, the day was bright, sunny, and beautiful - the perfect combination to make the snow and ice shimmer. Alana got ready at her parents' family home with her family and friends. Everyone was relaxing and enjoying some quiet time with hot cops of coffee as Alana was getting ready. Once Fancy Face finished Alana's make-up and she put on her JLM Couture dress, her look came together and she looked fierce and ready to pose for her bridal portraits!
Dan got ready at his parents' home as well with his son and two of his closest buddies by his side. Before getting dressed, all the boys headed down to the basement for a couple of quick games of pool, which were occasionally interrupted by the sweetest attention-seeking cat.
After a few rounds of pool, the boys went upstairs to get their clothes to start getting dressed. They all emerged proudly wearing just their shirts, underwear, and bright and colourful socks, which they got a kick from showing off (and of course mom and dad had to get in on the action as well). After a few attempts to get everyone's ties in order, and dad having to step in and give a helping hand, they were all set and ready to go.
Dan and Alana had an intimate first look in front of the waterfall at Ancaster Mill. Wearing her warm Ugg boots and a gorgeous faux-fur coat to keep her warm, with her cheeks flushed pink from the cold, Alana looked absolutely radiant, and it was clear that Dan thought the same when he turned around and saw his soon-to-be wife in front of him. After a few moments where Dan and Alana shared some giggles and caught up on their morning getting ready, we walked around the stunning property of Ancaster Mill for their couple portraits, taking advantage of all the architecture and snowy gardens. As we were finishing the portraits in front of the chapel, guests were already starting to arrive for the ceremony. While Alana scurried off to be out of sight, Dan made his way to the chapel to great guests with a cup of hot apple cider.
The Miller's Chapel at the top of the Ancaster Mill property is bright, spacious, and elegant, with a gorgeous fireplace at the front of the altar and amazing balcony views, framed by arched wooden beams. The Miller's Chapel is a perfect mix of old meets modern, and the perfect place to capture Alana and Dan say their I do's in front of their closest family and friends.
Following the ceremony, the guests made their way to the Solarium in the main building to enjoy cocktails, hors d'oevre, and stunning views of the waterfall and the stream below. In the meantime, Alana and Dan, along with their family and bridal party, bravely came out into the cold for their formal bridal party and family portraits on the private covered terrace adjoining their reception space in the 1812 Room, which is the original mill and the most historic room at Ancaster Mill. We had to be super efficient while organizing everyone and capturing the photos to ensure no one stayed out in the cold for too long and could get back inside to enjoy some more cocktails and appetizers before the reception started.
After a phenomenal dinner (did you know there is a restaurant at Ancaster Mill?? Highly recommend for a romantic date night!) and heartfelt speeches, the dance floor opened and everyone joined in. The absolutely highlight of the party was a father-son duet of Bohemian Rhapsody sung by Dan and his son. The bond and love shared between the two was clear as the young boy wiped away his tears. By the end of the song, we were also wiping away our tears behind the camera, but were reminded by the mother of the bride that it's ok and no need to hide. The whole day was just so sweet and beautiful that by the end of the night Diego and I were the biggest mush balls.
Dan and Alana, thank you so much for having us capture your beautiful day with your friends and family. It was absolutely lovely!


Also available in Black Coral, Americana and Sand.
* David is 6'3" and weighs 175 lbs. He is wearing our Aventura Jogger Sweatpants (Size Medium) in Blush paired with our Aventura Zip Up Hoodie (Size Large) in Blush.


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Deze lijst van voetbalinterlands is een overzicht van alle officiële voetbalwedstrijden tussen de nationale teams van Cambodja en Singapore. De landen hebben tot op heden negentien keer tegen elkaar gespeeld. De eerste ontmoeting, een vriendschappelijke wedstrijd, vond plaats in Shah Alam (Maleisië) op 13 november 1967. Het laatste duel, eveneens een vriendschappelijke wedstrijd, werd gespeeld op 16 oktober 2018 in Phnom Penh.

Wedstrijden

Samenvatting

Wedstrijden bepaald door strafschoppen worden, in lijn met de FIFA, als een gelijkspel gerekend.

Details

Vijftiende ontmoeting

Singapore
Cambodja

redpajama_set_name: RedPajamaWikipedia


Be the first to review this childcare provider. Write a review about Riverview High School Cyesis Teen Parent Program. Let other families know what's great, or what could be improved. Please read our brief review guidelines to make your review as helpful as possible.


3,929 others viewed this post.
"Eyes" are a shape that occur throughout the natural world as deceptive fakes, on the wings of butterflies, a leopards spots, caterpillars, butterfly fish, rays, sharks and so on. The peacock's dazzling display capitalizes on this motif to attract the attention, and hopefully the affection, of a mate. For most species eyes are a challenge, a threat and a defensive symbol. For others, like us homo sapien and our friend the peacock, they simply say – come hither.


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ACCEPTED

#### According to
Index Fungorum

#### Published in
C. r. hebd. Séanc. Mém. Soc. Biol. 108: 27 (1931)

#### Original name
Blastulidiopsis chattonii Sigot

### Remarks
null


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Technology & AI
AI platform Urbint funding rises to $109 million
By Dominic Ellis
Latest funding round enables Urbint to scale its technology to meet rising demand for its incident prevention software
AI platform Urbint has announced a $60 million Series C investment round, enabling it to scale its technology to meet rising demand for the company's incident prevention software.
The round, which raises its total investment to $109 million, was led by Energize Ventures, with participation from American Electric Power, OGCI Climate Investments, and existing investors Energy Impact Partners, National Grid Partners, Blue Bear Capital, and Salesforce Ventures.
Critical infrastructure companies use Urbint to stop failures, damages, and worker injuries before they happen.
With Congress expected to pass a $1 trillion infrastructure bill – the largest in a century – the coming years will bring unprecedented work to overhaul America's infrastructure and increase its resilience to extreme weather and other threats.
"America's infrastructure is at an inflection point. As we've seen time and again, mounting threats from climate change to an aging grid have made the risk of major safety incidents unmanageable," said Corey Capasso, Founder and CEO of Urbint. "Our technology equips the nation's energy and infrastructure companies with AI to prevent everything from fires, outages, and explosions to tragic worker accidents. This new investment will fuel our expansion to meet this unprecedented moment."
"Today's critical infrastructure owners and operators are facing new challenges as aging assets and climate change threats create a more complex operating environment," said Tyler Lancaster, Principal at Energize Ventures. "Electric utilities in the US alone spend more than $15 billion annually on operations and maintenance. Urbint's next-generation risk management software helps customers identify and prioritise safety and reliability threats, in turn lowering O&M costs, reducing emissions, and improving worker safety - all while ensuring critical infrastructure stays online."
"By protecting critical infrastructure, Urbint's technology prevented methane emissions equivalent to over 60,000 metric tons of carbon dioxide in 2020 alone," said Pratima Rangarajan, OGCI Climate Investments CEO. "We look forward to accelerating Urbint's climate impact by supporting their growth into new markets around the world."
Urbint pinpoints risks before catastrophe strikes, and its software powers preventative action across core programs such as construction, maintenance, and field operations. Urbint's customers include National Grid, Southern Company, and many other top energy and infrastructure companies.
The AI Dossier lists six value attributes
A new Deloitte AI Institute report, The AI Dossier, examines the most compelling business use cases for AI across six major industries, including energy.
The report looks across all the industry-specific use cases to identify six major ways AI can create value for business:
Cost reduction Applying AI and intelligent automation solutions to automate tasks that are relatively low value and often repetitive, reducing costs through improved efficiency and quality
Speed to execution Reducing the time required to achieve operational and business results by minimising latency
Reduced complexity Improving understanding and decision making through analytics that are more proactive, predictive and able to see patterns in increasingly complex sources
Transformed engagement Changing the way people interact with technology, enabling businesses to engage with people on human terms rather than forcing humans to engage on machine terms
Fueled innovation Redefining 'where to play' and 'how to win' by using AI to enable innovative new products, markets and business models
Fortified trust Securing a business from risks such as fraud and cyber, and improving quality and consistency while enabling greater transparency to enhance brand trust
"Artificial intelligence has made the leap to practical reality and is quickly becoming a competitive necessity. Yet, amidst the current frenzy of AI advancement and adoption, many leaders are questioning what AI can actually do for their businesses," said Nitin Mittal, U.S. AI co-leader and principal, Deloitte Consulting LLP. "The AI Dossier can help these leaders understand the value AI can deliver and how to prioritize their investment in AI, today and in the future."
Deloitte's State of AI in the Enterprise, 3rd Edition study found that 74% of businesses are still in the AI experimentation stage with a focus on modernising their data for AI and building AI expertise through an assortment of siloed pilot programs and proofs-of-concept, but without a clear vision of how all the pieces fit together. By contrast, only 26% of businesses are focused on deploying high impact AI use cases at scale, which is where AI can create real value.
energyTechnologyAIInfrastructure
AMEA Power awarded 120MW solar project in South Africa
200MW renewable hydrogen hub planned in Galicia, Spain
North America's natural gas can help mitigate energy crisis
51% of global JinkoSolar facilities powered by clean energy
UK and US announce energy partnership
The agreement will work towards reducing global dependency on Russian energy exports, stabilising energy markets, and stepping up collaboration…
Alfa Laval to supply world's largest green hydrogen plant
The facility is being built in NEOM, the US$500bn futuristic city being developed in Saudi Arabia…
COP27 agrees to climate compensation fund
The deal is said to be a historic first in acknowledging the vast inequities of the climate crisis…
COP27: Egypt and Norway to build 100MW green hydrogen plant
Renewable energy company Masdar opens office in Saudi Arabia
Ørsted closes US$140m transaction with ECP for US portfolio
ADNOC Drilling delivers world record well at Upper Zakum
GIP Mubadala complete 100% acquisition of Skyborn Renewables
Qatar's first large-scale solar power plant starts operation
RWE selects preferred suppliers for Thor offshore wind farm

redpajama_set_name: RedPajamaCommonCrawl


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Pat Metheny Side-Eye – NYC (V1-IV)
Side-Eye – NYC (V1-IV)
Modern Recordings
No 'jazz' musician except Chick Corea has amassed more Grammy awards than Pat Metheny but the use of quote marks around jazz indicates that both for Corea and Metheny, some of these awards were due to projects in other genres besides jazz. Our greatest artists are both consistent and unpredictable. No one is quite sure what Metheny will take on next, and that is part of his compelling, enduring, appeal. Consider that Metheny is the only musician to have won twelve of his twenty Grammy awards in twelve different categories. His recent recording, Road To The Sun, garnered attention in the classical music world for its intricate chamber music compositions. At the same time, its immediate predecessor From This Place was Downbeat magazine's Jazz Record of the Year as an expansive and timeless large-scale work.
Pat Metheny Side-Eye- NYC is a new trio platform for the guitarist, featuring both new music and creative re-workings of Metheny classics, all recorded in front of a live audience at Sony Hall in NYC. Metheny hopes that it might become a rotating group of musicians who could come and go in different combinations. So far, there have been four iterations, hence the V.1-IV sub-heading on the record. Metheny is tapping into this next generation of players that includes folks like Immanuel Wilkins, Joel Ross, Derrick Hodge, Marcus Gilmore, James Francies, and others. The latter two are part of this recording. Metheny explains, "…About every ten or twelve years, there seems to be a crop of players coming along who find a certain resonance with whatever it is that my thing seems to represent to them. The last time that happened was the Josh Redman, Christian McBride, Brad Mehldau, Antonio Sanchez generation, and it seems to be happening again now."
Interestingly, drummer Eric Harland, who plays in Chris Potter's Circuits trio with Francies, suggested the young keyboard whiz to Metheny. When Metheny suggested they get a bass player, Harland said none was needed with Francies. Potter's trio doesn't have one. Francies is noted for his rapid runs, inventive use of textures, complete command of and ability to play multiple keyboards, both acoustic and electric, simultaneously (i.e. "Bright Sized Life"). This writer witnessed Francies at work in Newport, both with Potter's trio and, for the first time, with Christian McBride in an electric, turntablist driven group called Christina McBride Situation. And, by all means check out Francies' Blue Note debut as a leader, Purest Form, that dropped in May. Suffice to say that Harland offered a strong recommendation. Despite the generation gap, Metheny and Francies have such similar sensibilities, that they match perfectly.
After some sessions with Harland, Metheny turned his attention to some of the new drummers making a 'buzz' on the scene, among them Philly drummer Anwar Marshall who works often with Orrin Evans and is featured on the new Jazzmeia Horn big band project, Dear Love, that also drops this week. After that it was Nate Smith, who also has his own album, Kinfolk 2 – See the Birds, issuing next week. That's a round about way to getting to Marcus Gilmore, grandson of the living legend Roy Haynes, for this outing. NOLA drummer Joe Dyson, who works with Christian Scott aTunde Adjuah, will be on tour with the group this Fall.
Metheny says, "In recent years, with the newer kinds of musicians that are around these days, it is more likely that I can put together groups of musicians where nothing is mutually exclusive to anything else, The kinds of players that will fit into the profile of the Side-Eye thing will certainly have to have that kind of range. The constant factor for me as a leader from the beginning, regardless of who I invite along the way, is to draw on the strengths of the players I have with me at the time and to encourage everyone to do their best."
There is over a half our of new music on this recording, beginning with the opening nearly fourteen-minute composition called "It Starts When We Disappear", like many Metheny pieces explorative beyond the simple head/solo/head format and featuring stunning solos from both Metheny and Francies. One will quickly grasp that this configuration is much like the classic organ trio upon which Metheny comments, "At its core, this is a kind of "organ trio"; but an organ-trio for the 21st century. James has the capacity to play bass lines with his left hand that rivals the great Jack McDuff, my favorite "bass player" of all the classic organ guys. But additionally, I can play bass from guitar now too. I wanted to push the whole idea of a keyboard/guitar/drums trio. I was interested to see what would happen if I got some of my orchestrionic instruments involved too, a whole other dimension of challenge to add to the equation. Those instruments are featured on the opening and closing tracks." {closing track is "Zenith Blue."}
Following the opener, Metheny then completely transforms his own "Better Days Ahead that dates back to 1981 or 82 but was first recorded in 1989 with the Pat Metheny Group on Letter From Home. Riding Gilmore's groove and Francies' blues and gospel roots, Metheny turned the sunny Brazilian inspired melody into a dark, smoky, R&B backbeat that puts a new spin on his signature lyrical delivery.
Surely, the "organ-trio for the 21st century" is at the heart of the record but the trio honors original tradition with "Timeline," a piece he had never performed before that was written for a Michael Brecker album that featured both Metheny and the great drummer, Elvin Jones. "Lodger" is another piece that has not appeared since his recording of John Zorn's TAP, or maybe even going back to The Roots of Coincidence and it finds Metheny in full rock mode. The piece is dedicated to and inspired by his friend and one of his favorite guitar players, Adam Rogers, and features heavy organ contributions from Francies. Both Metheny and Francies are so versatile with electronic effects, sometimes it's difficult to identify who is leading the melody. "Lodger" just keeps swelling and building until it recedes peacefully at the close. "Sirabhorn" is an abstract blues while Ornette Coleman's "Turnaround" straddles the line between traditional and more contemporary organ trio fare.
The Side-Eye series is the latest chapter in Metheny's nearly approaching five decades career. His new sidekicks are keeping him invigorated.
Jim Hynes
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Can I Kick It? YES YOU CAN!!!
One of the best parts of a table top game is the ability to create any type of character you want. Typically, I choose the warrior type with lots of weapons and stats that benefit a tank type character. But what if you had to go through a campaign as a pacifist? Lotus Dimensions is a D&D type game that requires you to solve problems in non-violent ways. Characters such as the hacker or mystic will have stats and abilities based on the concept of Karma and the eight-fold path of Buddha. The starter set includes pre-made quests with a "guru guide" to help lead the party through the quests. I have never seen an entire party be passive during a table top session, so it would be really interesting to see how the party solves problems in a non-violent way. The project has 28 days to go. Click HERE for more details!
I love my 32 bit action games, and Heart Felt Games is bringing us a top down shooter with a 32 bit look. You play as a brother and sister duo who are stuck in probably the worst scenario possible. You are stuck in the middle of a zombie outbreak, alien invasion, robotic uprising, and invasion of demons. How in the world can you survive against this many apocalyptic nightmares? With tons of weapons! The game is a twin stick shooter that feels like Contra. For more information, and a link to a demo, click HERE. The project has 7 days left, so hurry and support it if you are interested!!
We had the chance to check out Ethos: It Begins Again at Salt Lake Gaming Con. The idea is really ambitious – create an Action RPG/MMO with city building aspects, all in a sandbox environment. It sounds complicated, but think of the options. You would be able to create a character to take on Dark Soul-like bosses and save various kingdoms. You would be able to build cities and run shops. You could become a bounty hunter, a farmer, or a miner. You can expand your empire buy defeating other players. It sounds like a ton of possibilities. If this type of game is appealing to you, then click HERE to see developer interviews and support the project! There are 19 days left on Kickstarter.
That is it for us this week! Please feel free to comment on these projects and make sure to let us know about any interesting projects to feature for next week! See you all next time!!


ALISO VIEJO, CA—GlobeSt.com has learned exclusively that Bixby Land Co. has added another project to its investment portfolio with the purchase of 26880 Aliso Viejo Pkwy. here from Harsini AVP Holdings LLC for $11.6 million. The acquisition is the fifth project the firm has purchased over the last two years in Orange County, including its most-recent $44.25-million buy of the Kawasaki headquarters building in Irvine, CA, last month.
The 53,115-square-foot office building is located in Town Center Corporate Park and was 69% vacant at the time of sale. Bixby will invest new capital into interior building upgrades and tenant finishes, along the lines of the redevelopment work the firm has performed on several properties throughout California over the last five years.
For this project, Bixby will focus its efforts on the lobby and tenant spaces since the project, built in 2000, requires little exterior work. The firm has been more widely known for undertaking projects that require significant development to be converted to creative office.
According to CBRE, the Aliso Viejo market had a 3.2% office vacancy rate at the end of Q1 2015, with no new office projects under construction. This figure is even tighter than the South Orange County vacancy rate of 6.8% at the end of the quarter.
Harsini was represented in the transaction by Doug Matthews and Gary Allen at Newmark Grubb Knight Frank, while Bixby represented itself. Matthews and Allen have also been retained to represent leasing for the building, which is targeted toward tenants seeking between 7,000 and 19,000 square feet of space. The building improvements are scheduled to be completed in the fourth quarter of this year.
As GlobeSt.com reported in April, true creative space won't work in every building or in every market, according to Bill Halford, CEO of Bixby. Halford told us exclusively that areas where tenants are focused on competing for talent are better candidates for true, amenitized creative-office space.


Today, The Lone Bellow are back with the announcement of their third studio album, Walk Into A Storm out September 15th on Descendant Records/ Sony Music Masterworks. The album was produced by Dave Cobb (Chris Stapleton, Sturgill Simpson, Jason Isbell) and recorded in Nashville, TN. The first single, "Time's Always Leaving" was released today.
The Lone Bellow will hit the road in support of their new album beginning September 21st with Central Park's Summerstage supporting The Head and The Heart. Highlights include a performance at Toronto's Opera House, Chicago's Thalia Hall and Washington DC's 9:30 Club. All November tour dates will be supported by The Wild Reeds.
It's been three years since the band's victorious, Then Came The Morning was released. The album was produced by The National's Aaron Dessner and nominated for an Americana Music Award. The Lone Bellow appeared on Kimmel, Letterman, Conan, CBS This Morning, Later…with Jools Holland and James Corden in support of the album. In the years since the release the band left their beloved adopted home of Brooklyn and moved to Nashville, TN.
Additional album details and tour dates will be announced soon!


But I usually fail at some point.
my dear, are you waiting for someone?
turning old watery eyes on me.
They don't ask for my story.
because it's just another thing I have to strip off.
so they can't find each other.
and that I needed to find a breast surgeon.
because that was on the first mixtape you ever made me.
Neil Young can do it.
But Bruce is the worst.


Recently I was asked by our sisters (www.sosj.org.au) to write a reflection in light of the upcoming World Refugee Week. I've focused the article on Citizenship... I would love to hear if anything sticks with you?
What kind of citizen are you? Are you an Australian Citizen, perhaps a citizen of New Zealand or of Canada?
If I say, "I am a New Zealander" or "I am an Australian" what does that mean? As a person born in New Zealand I'll admit shockingly that I'm not a fan of Rugby, I have a dairy allergy, I do not own 1000 Sheep – in many ways I don't fit the status quo for being a 'Kiwi'!
The undercurrent that runs like a raging torrent behind my statement: "I am not just a New Zealand Citizen" is my belief in not separating self from others by singling out my citizenship status.In other words, I am not just a New Zealand Citizen; I am a World Citizen.
I believe with my whole heart that all people are equal, that all are world and global citizens. The fact that I have won the birthplace lottery should not entice me into thinking that I'm entitled to more than anyone else.
A wonderful Ted talk, "What does it mean to be a citizen of the world?" is also well worth a watch.
Don't get me wrong, I'm all for the Olympics and love competition between countries; this should be fostered and developed. We have an abundance of rich cultural diversity between our World nations. There is beauty in diversity.
As a human race, a world, can't we be bigger than citizenship division?
Governments have made decisions to close borders to ensure the masses are kept happy, to put at ease the fear of 'they will take our jobs'.
But how about we look at that word 'they'. Why are 'they' separate from us, what makes them less than us? Does having a Syrian passport mean that its holder bleeds differently; don't we all bleed red?
Perhaps on this World Refugee Day we need to remove citizenship status.
When you turn on the TV news and see Refugees stranded at borders, try not to think about what country they were born in. Look at their feet, think about where they have walked today, see their viewpoint, their need, and embrace their journey. 'They' are world citizens too.
There is beauty in diversity and growth through embrace.


More and more homeowners are considering adding Minneapolis heating systems to their garages. Technology used to keep garages warm has changed in order to make it safer and more effective. But why would anyone consider doing this? What are the benefits of installing a heater for your garage? Here are five reasons that people should consider.
Freezing temperatures expose people and possessions to damage. If a person has ever dealt with a dead battery on a freezing morning, they understand the impact that the cold can have. On top of damage to a car battery, the cold also impacts other parts of the car as well as appliances and garage components. In order to protect all of the possessions and hardware in the garage, a heater can ensure that freezing temperatures won't affect it.
In some areas, homeowners' associations and other neighborhood codes require homes to have built-in heaters in their garages. This requirement protects homes from wear and tear caused by the weather. It can also protect homeowners and their pets in freezing temperatures. Find out if your neighborhood codes specify whether or not a garage heating system is required.
For homeowners that decide to use their garages as living space, having a heater in this area will make the renovations much easier. Some people choose to upgrade their garages to a small apartment, extra bedroom, or family room in order to increase the finished square footage and livable space in the home. While completing the renovations to do this, homeowners need to install a way to keep this space warm. Adding a heater to the garage now will make any future developments much easier and quicker.
Adding insulation to garages and crawlspaces help homeowners keep the warm air inside of their homes. The garage still allows a lot of cold air into the home, especially when the temperature plummets below freezing. Check the walls that are shared with the garage. If they're cold, then it can impact the temperature of the home.
Heating the garage will help maintain warmer temperatures inside of the home by preventing cold air from getting inside of the home, so homeowners can maintain their desired temperatures and keep their homes comfortable.
Many homeowners use the garage as a workspace. Whether they work on cars, complete home renovations, or do other things in their garage, this workspace allows them to have the lights, electricity, and workspace needed for the projects. Unfortunately, many people freeze as they work in their garages. If they do a lot of work in the garage, it would be to their benefit to add a heater to the workspace. Then they can work at whatever hours they please without freezing.
Whether homeowners spend a lot of time in their garage or not, adding heating to the garage can be a great way to protect the people and things in there. Make sure to have a professional help with the installation to ensure that it's done correctly and won't create a potentially dangerous situation for the members of the household.
Looking for an HVAC professional to install garage heating for your home in Minneapolis-St. Paul? Contact Total Comfort today!


Old Tom Gin was all the rage in 18th century England. Old Tom's are known as a fuller bodied and sweeter style of gin. Today the style has seen a great resurgence and has opened the door for many gin makers to play around with oak aging. This gin is made from 100% pot distilled corn, juniper, and "other botanicals inspired by the spice trade of the prevailing era." It is aged for 1 year in bourbon casks and then finished in oloroso sherry casks. The final product is bottled at 50.05% ABV.
"This is surprisingly light and balanced for a high-proof spirit. Everything on the nose has been sweetened a little. Juniper, sweet chamomile, honeyed lemons, and rich vanilla are front and center. The palate is lean and silky. On the palate, more honey, ripe citrus fruit, some bitter juniper, and a sweet grass finish that is often found in Rhum Agricoles. Because of its balance this could be used in a wide variety of cocktails, but an Old Fashioned should be at the top of the list."


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Guelph Civic Museum: Lots of Hands-On Exploring For Children
January 17, 2023 January 17, 2023 / Ages - Kids 4-10, Daytrips and Destinations, Guelph, Indoor Activities
You know how much we love a children's museum, and the Guelph Civic Museum has a wing dedicated to hands-on fun for kids that we know you'll love.
Where is the Guelph Civic Museum?
You already know the city it's located in, but there's more. The Civic Museum is located quite central in the city, and has lots to see within walking distance. Once you've explored the many floors of the Civic Museum, we suggest checking out the beautiful architecture of its next-door neighbour the Basilica of Our Lady Immaculate because it's beautiful. In the warm months, you can also shop at the Guelph Farmer's Market for snacks and fresh lunch ideas.
Is The Guelph Museum Good For Kids?
In a word, yes! Our favourite part of the museum, and where we spent all of our time, was the Children's Gallery. The children's gallery has multiple sections that cover a variety of topics from dinosaurs to the future of the environment.
Listen and learn about Ontario's Indigenous peoples and how they have always taken care of the planet and all of its creatures.
Learn about Ontario's early settlers and how their daily lives differed much – but not too much – from the daily lives we live today.
Dinosaurs in Guelph? Absolutely! Your kids will love discovering that mammoths and mastadons once roamed the very streets they are walking today!
Become an eco-warrior when you learn about nature preservation, the watershed and water consumption.
Kids won't realize how much they are learning through the hands-on immersive activities offered in the children's gallery at Guelph Civic Museus, but parents will notice when their dinner conversations are enlightened! I love asking kids open ended questions to watch their brains light up with thoughts.
Take a 3D tour of the family gallery here.
What Else Is There To Do At The Guelph Civic Museum?
The Civic Museum in Guelph has a number of galleries, each home to permanent collections or new exhibits. Learn about the history of the area and where Guelph sees itself in the future.
How Much Is Admission To the Museum?
The Families Gallery is open for drop-in visits from 11:00am-5:00pm, Tuesday-Sunday. Pre-booking is not required during these hours.
If you wish to visit the Families Gallery privately (with your social bubble), pre-booking is required for the 9:30 AM – 10:30 AM timeslot. Click here to book that private timeslot.
With a Families Gallery reservation, you will be able to explore the rest of the Civic Museum during your visit. You will also receive a voucher for a future visit to McCrae House.
Guelph Civic Museums is located at 52 Norfolk StreetGuelph, ON N1H 4H8
guelphmuseums.ca
More Ideas For Family Fun
We have visited hundreds of places and written about them to help you find the very best destination for your next day trip or outing. We love sharing indoor play places, playgrounds that go above and beyond, and more! Here are a few of our latest blogs to help you have a great weekend.
Music Lessons and Theatre Programs For Kids
How To Borrow Free Parks Passes From Your Library
Art Gallery of Hamilton – How To Visit For Free!
Valentine's for Veterans


Likely story right? I sat alone, drinking my glass of wine like I normally did on a Thursday night after a long day at work. I often struck up conversation with the bartender or couples sitting near me who had stopped in for a quick bite to eat.
I tried to void talking to single men, mostly because it was the same old story. They had just moved to Los Angeles to be in a band and were excited to be cutting a record at the studio down the street. Music had saved them, yada yada blah blah blah. I could already feel the disappointment I'd eventually face when I'd wake up in the morning and they'd be gone, never to be seen again.
It was like a broken record. That was until the night I met Hunter.
I'll be honest, he had that same "musician look" – you know, the one where they wear the torn black jeans, shirt just tight enough to make you wonder what's underneath and a leather jacket even though it couldn't be more than 76 degrees outside.
As he walks past me the smell of his cologne fills my nostrils and I turn to look at him. Our eyes meet but I quickly look away. "Not another one" I whisper to myself. Be strong.
He sits one bar stool away from me and orders a beer. I can see every girl trying not to stare at him, but failing miserably. Poor fools.
He takes a sip of his drink and I can't help but watch his lips touch the glass and immediately think about them touching my skin ever so gently. A man like that has to know exactly what to do with lips like those.
I fumble with my words, but I get something out that must've been something resembling a No because he moves into the seat next to me.
I'm intrigued so we begin to talk about where we've been and where we're headed. It's all the same typical type of conversation. We move closer to one another, he's less of a stranger now and I can feel the chemistry building.
There are no words for the connection I'm starting to feel with him. I can feel my desire growing, every part of my body just aching for him to touch it. He keeps his distance, but I long for the moment when he breaks the barrier and touches me.
I don't know why but I go with him. There's something about him that I simply cannot resist hanging on his every word.
He leads me out of the bar and through a dimly lit hallway. As we reach the middle of the hallway he turns and presses me against the wall. My eyes are locked on his. There is a part of me that is filled with both pleasure and fear.
I fumble slightly as I reach into his pocket, pull out his phone and type my number. I hit save and look him in the eyes for my next instructions.
I nod yes. He releases me and I walk to my car. I drive home recounting what just happened. Why was I so turned on by this idea. This man is a stranger and no one has ever talked to me the way that he did. What am I doing?
I walk into my apartment and without skipping a beat, I take off my clothes, get into my bed and stare at my phone.
After about 20 minutes of pure anticipation my phone dings.
I respond with, "Yes, I have".


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He-Man & Masters of Universe: Minicomic Collection Vol. 1
He-Man & Masters of Universe: Minicomic Collection
THE MOST POWERFUL STORIES IN THE UNIVERSE! The toy juggernaut Masters of the Universe and its subsequent action figure lines featured memorable pack-in minicomics that aided in playtime for children across the world. This two volume digital collection features sixty-eight US releases, including all minicomics from the eighties Masters of the Universe line, the eighties Princess of Power line, and the eighties and nineties He-Man line, plus an introduction to the minicomics in the current Masters of the Universe Classics toy line. Relive the illustrated adventures that fueled your imagination!
9+ Only
Steven Grant Robert Kirkman Scott Neitlich Tim Seeley Phil White
Larry F Houston Jim Mitchell Mark Texeira Bruce Timm
In 1983, the world was introduced to He-Man and the Masters of the Universe. What followed was a cultural sensation that changed the landscape of children's entertainment forever! Join Mattel and Dark Horse in this comprehensive retrospective chronicling He-Man's decades-long epic journey from toy, to television, to film, to a true pop culture phenomenon!
He-Man: The Eternity War (2014-2016)
The war to end all wars has begun in Eternia! Hordak and the villainous Dark Horde have taken over Castle Grayskull and plan to use it as a weapon to terrorize and rule the universe. But a resistance is building led by She-Ra, The Sorceress Teela and the benevolent warrior He-Man!
Just what makes the heroes and villains of Eternia Masters of the Universe? These digital tales of triumph and terror will give you an inside look into the allies and enemies of He-Man, the Most Powerful Man in the Universe.
He-Man and the Masters of the Universe (2013-2014)
Whenever Prince Adam holds his Power Sword aloft and says the magic words "By the Power of Grayskull, I HAVE THE POWER" he is transformed into He-Man, the most powerful man in the universe. Together with his close allies, The Masters of the Universe, He-Man uses his powers to defend Eternia from evil.
Adam's dreams are plagued by visions of a powerful warrior with his face who battles the armies of Skeletor, but why would a simple woodsman challenge the ruler of all Eternia? A magical falcon confirms his dreams are real, beckoning him to begin a journey to reclaim his power and free the Masters of the Universe.


Our piggyBac shRNA Knockdown vector system is a simple and efficient method for stably knocking down expression of a target gene in a wide variety of cell types. This transposon-based system utilizes plasmid transfection (rather than viral transduction) to permanently integrate an shRNA expression cassette into the host cell genome. The shRNA is expressed from the human U6 promoter, leading to degradation of target gene mRNA. The permanent nature of knockdown by the piggyBac system has several major advantages over transient knockdown by synthetic siRNA (see Advantages section below).
The piggyBac shRNA knockdown system contains two vectors, both engineered as E. coli plasmids. One vector, referred to as the helper plasmid, encodes the transposase. The other vector, referred to as the transposon plasmid, contains two terminal repeats (TRs) bracketing the region to be transposed, which includes the shRNA-expression cassette.
When the helper and transposon plasmids are co-transfected into target cells, the transposase produced from the helper plasmid recognizes the two TRs on the transposon, and inserts the flanked region including the two TRs into the host genome. PiggyBac is a class II transposon, meaning that it moves in a cut-and-paste manner, hopping from place to place without leaving copies behind. (In contrast, class I transposons move in a copy-and-paste manner.) Because the helper plasmid is only transiently transfected into host cells, it will get lost over time. With the loss of the helper plasmid, the integration of the shRNA-expressing transposon in the genome of host cells becomes permanent. If these cells are transfected with the helper plasmid again, the transposon could get excised from the genome of some cells, footprint free.
Our piggyBac transposon vector along with the helper plasmid are optimized for high copy number replication in E. coli, and efficient transfection into a wide range of target cells. The human U6 promoter drives high-level, constitutive transcription of the shRNA in mammalian cells, while our optimized shRNA stem-loop sequences mediate efficient shRNA processing and target gene knockdown.
Permanent integration and knockdown: Conventional transfection results in almost entirely transient delivery of DNA into host cells due to the loss of DNA over time. This problem is especially prominent in rapidly dividing cells. In contrast, transfection of mammalian cells with the piggyBac transposon plasmid along with the helper plasmid can deliver DNA sequences carried on the transposon permanently into host cells due to the integration of the transposon into the host genome. Additionally, the U6 promoter directs constitutive expression of the shRNA. For these reasons, the knockdown of the target gene is stable and permanent. This can be an important advantage for many experimental goals. It allows long-term analysis of the knockdown phenotype. It facilitates the isolation of clones having different levels of knockdown and/or different phenotypes. When the knockdown vector carries a fluorescence marker such as EGFP, it also allows cells with different amounts of transposon integration (and hence potentially different levels of knockdown) to be isolated by flow sorting cells with different fluorescence intensity.
Reversibility: If cells carrying a piggyBac shRNA transposon are transfected with the helper plasmid again, the transposon may be excised from the genome of some cells, footprint free, eliminating expression of the shRNA from those cells. However, this will occur in only a subset of cells.
Technical simplicity Delivering plasmid vectors into cells by conventional transfection is technically straightforward, and far easier than virus-based vectors which require the packaging of live virus.
Safety: Conventional transfection does not have the safety concerns which are often associated with viral vectors.
rBG pA: Rabbit β-globin polyadenylation signal. It facilitates transcriptional termination of the upstream marker gene.


At 01:00 on 8/4/15 Northwest Weather Zones 2 and 3 will drop back to an Industrial Fire Precaution Level of 2. Northwest Weather Zone 1 will drop back to a level 1.
This is because the fine fuels likely to catch a spark are rising in moisture, and so we think that by tomorrow those activities prevented by IFPL Level 3 can now be allowed.
The heavier fuels remain at record dry levels, drier than they were when the Scoggins Creek Fire broke out last year, so preventing a start remains very important. You can see these fuel moistures by clicking on the map of our area in the fuels consider condition tab of this site. Notice the thousand hour fuels.


EPFL Executive Master in e-Governance - UOC/Barcelona week.
Click inside the references to get information on where to download the documents from.
ITU, OECD and WEF reports. They are not required to be read in all their legth but the Executive Summaries suffice – again, click on the references and scroll down to "Observations" to get the required links.
International Telecommunication Union (2006). World Telecommunication/ICT Development Report 2006: Measuring ICT for social and economic development. Geneva: ITU.
OECD (2005). OECD Communications Outlook 2005. Paris: OECD.
OECD (2006). OECD Information Technology Outlook 2006. Paris: OECD.
OECD (2007). OECD Communications Outlook 2007. Paris: OECD.
OECD (2008). OECD Information Technology Outlook 2008. Paris: OECD.


India is home to many companies manufacturing rotating machinery and industrial equipment. Entuple with its Ansys Design and Analysis capability can help design motors and provide analysis of the same.
Entuple has the capability to provide design and analysis from IE1-IE5 standard for motors. You can also download Entuple's rotating machine handbook here.
As the World Turns World conditions and increased competition challenge rotating machinery designers to deliver higher levels of performance, efficiency and reliability — faster than ever before. By Brad Hutchinson, Vice President Industry Marketing, Aerospace and Turbomachinery, ANSYS, Inc. Spotlight on Engineering Simulation for Rotating Machinery Turbomachinery, or more broadly speaking rotating machinery, spans almost all industry sectors and in many plays a vital role. Rotating machines change the state of working fluids (pumps or compressors), convey or transport fluids (fans and pumps), extract energy (turbines) and create propulsion (propellers). Performance, efficiency, reliability and rapid delivery have always been important, but today's world conditions intensify the pressures designers face.
Currently, the price of oil hovers near $100 per barrel. Concern for climate change is widespread, not only by the general public but also by legislators worldwide. Since rotating machines play a critical role in power generation and various forms of transportation — and, in some cases, are the limiting factor regarding cost, efficiency and emissions — it is natural that they are in the spotlight and the subject of intense analytical scrutiny. In the energy industries, most of our power is produced by gas, steam and water turbines. Steam turbines extract power in nuclear and coal-fired power plants. Land-based gas turbines, similar to their aeroengine cousins, run on natural gas and, in some cases, oil. Although still relatively small in volume, wind turbine production has increased dramatically in recent years, with the largest machines being 6 megawatts (MW) in size and having rotors approaching 130 meters in diameter. The largest water turbines, such as those used in the Three Gorges Dam in China, have 10-meter diameter runners. In the transportation industry, turbomachinery plays an equally important role. For air travel, the rotating machinery used on commercial aircraft is well known — the gas turbine aircraft engine. Its key rotating components include the fan, which can be seen when boarding the plane, as well as the compressor and the turbine.
Since fuel is a major and often volatile cost for airlines (significantly impacting their profitability) and noise and emissions regulations are becoming increasingly stringent, there is a drive for cleaner, quieter and more fuel-efficient engines. For transportation at sea and on the ground, diesel engines in ships, trucks and an increasing number of cars use turbochargers to improve their performance and efficiency. These engines also use electric-driven fans and pumps, which must be optimized, since available electrical power is limited. Efficiency of the automatic transmission torque converter — another rotating machinery component comprised of a pump, a stator and a turbine — is critical to vehicle fuel efficiency. Turbomachinery plays an important role in other industries as well. Compressors and pumps are important to the chemical, process, and oil and gas industries, and are even key components in large industrial air conditioning systems. In the medical industry, heart pumps must be designed to be compact and to minimize blood damage. Each rotating machine type has one or more key design challenges. Cooling due to high temperatures is problematic in gas turbines. Cavitation is an issue in pumps. Non-ideal gas behavior in steam turbines and refrigerant compressors must be considered. In aeroengine fans, noise is a challenge. There are space limitations when designing automotive fans. For hydraulic turbines, large-scale transient instabilities — also known as vortex ropes — may occur at offdesign conditions.
These examples indicate the diverse physics requiring consideration for accurate simulation of real machine behavior. In reality, these physical processes interact, and multiphysics analysis increasingly is becoming a requirement for high-fidelity simulations. Several design, performance or production factors are common among turbomachine types. Reliability and safety require accurate prediction of steady and transient thermal, aerodynamic and structural loads for stress and fatigue life predictions. However, excessive safety and strength features are likely to make the machine too expensive or too heavy; these features also can preclude other competing requirements such as efficiency. Operational cost and emission issues have recently intensified the pressure to produce efficient machines. Timeto-market and cost pressures resulting from competition have underscored the need to "get it right the first time." These factors, in turn, demand that simulation software provides solutions of ever-increasing resolution and accuracy. Software, when employed in Simulation Driven Product Development (SDPD), helps designers resolve these and other challenges and is a key enabler for reduced-cost, first-to-market rotating machinery development.


Tamalpa UK runs regular weekend Tamalpa Experience Workshops throughout Great Britain.
The Tamalpa Experience Workshop introduces an approach that enlivens dialogue between body and imagination, life experiences and art making. Using movement, drawing, writing and improvisational performance, participants will tap into art's symbolic language to explore current life themes and generate new resources.
If your body could speak, what would it say?
These 2-day intensive workshops are designed to give participants an experiential understanding of our work in movement-based expressive arts.
Recommended as an introduction to our larger training programmes.
See the Tamalpa-UK website for further information on the variety of workshops on offer.
Watch this video from Daria Halprin, one of the founders of the Tamalpa Life Art Process.
In 2018, Tamalpa-UK will be again running the Level 1 Personal Mythology Training, based on the work of Anna Halprin and Daria Halprin, in Kent.
This is a unique, year-long movement based expressive arts programme beginning April 2018 and run in association with The Tamalpa Institute, California.


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Long IslandSuffolk
Police look for clues in East Patchogue home invasion
By JOHN VALENTI john.valenti@newsday.com Updated March 12, 2010 3:43 PM
Three masked men pistol-whipped three victims at a home in East Patchogue, tied them up, burglarized the place, and hours later one of the men was believed captured on a surveillance camera attempting to use a stolen credit card, police said.
Suffolk County police are looking for information on the trio who committed the Dec. 29 break-in on Washington Avenue in East Patchogue.
Police said the three burglars stole $500, a laptop computer and other items. They pistol-whipped three of the four people inside the house, tied up all four and fled in a dark vehicle, police said.
Hours later, one of the stolen credit cards was used at Track gas station in Bellport, as well as at a Stop & Shop in Medford and a 7-Eleven in East Patchogue, police said.
A black 2005 or 2006 Honda Accord was also seen on surveillance footage, the same type of car seen leaving the site of the home invasion.
In the footage from one of the stores - taken after the robbery - a woman was seen, along with a man, believed to be one of the three, police said.
Police are asking anyone with information regarding this incident to contact Crime Stoppers at 800-220-TIPS. All calls will remain confidential and callers are eligible for a reward of up to $5,000.
By JOHN VALENTI john.valenti@newsday.com


Umang Pharmatech Pvt. Ltd. is in the core business of Pelletization and Encapsulation. Company is established in the year of 1982 by Mr. Rajkumar Budhraja. Company Setup is Plant at Vasai (East) Mumbai Maharashtra, with manufacturing activity in the area of 120000 Sq Ft. Having Corporate office in the same premises. Business been started with manufacturing of Pharma Machinery (Extruder & Spheronization). Today in India all most all Pharma company having Umang's machinery.
In 2008 Umang has Expanded his business by entering into business of Encapsulation for Personal Care, Cosmetics, Nutraceuticals and Health Care is under process.


Hello Guys! I'm in need of oil for my 03 Dodge and 91 Mercedes 350SD. I live in North Central Arkansas but regularly travel to the Gulf Coast in Louisiana for work. Little Rock, Texarkana, Shreveport, Ruston, Lafayette, Houma, New Orleans. I also have family in Nashville and Birmingham and I go through Memphis. I'm also relatively close to Springfield, Tulsa and Dallas.
Any information or leads on steady sources would be greatly appreciated. Any quantities as I could periodically gather, ie monthly, quarterly, semi-annually etc. Ideally I need 150 gallons per month.
I have some oil I would like to get rid of. About 100 gallons is centrifuged and ready to run, I have another 100 or so that is dirty. $50 for all of it... I am about 5 miles West of Lafayette, LA. Please let me know if you are interested. I have a lot of equipment for sale also. I am getting out of the business, after running WVO since 2006, just don't want to mess with it anymore. I have some 275 gallon totes, pumps, two centrifuges, tanks, let me know if interested.
I apologize for the delay but I have not been working this year and driving to LA until this month. Do you still have this oil?


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Łomy est un toponyme qui peut désigner :

Łomy, village de la voïvodie de Lubusz
 Łomy, village de la voïvodie de Varmie-Mazurie
 Łomy, village de la voïvodie de Podlachie

Voir aussi
 Lomy


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Travelers EDGE 10th Anniversary
Scholars Share Their Stories
Travelers EDGE® Scholars Share Their Stories
Over the past decade, the Travelers EDGE® (Empowering Dreams for Graduation and Employment) Program has helped more than 440 students gain access to higher education, professional mentoring, internships and a career in the insurance and financial services industry. Many of them are the first in their families to attend college. Take a look and see how the program has shaped so many of their lives as well as the entire Travelers community.
Travelers EDGE® Marks its 10th Anniversary
Travelers EDGE® partners with colleges and community programs to increase access to higher education for underrepresented students. As Travelers EDGE celebrates its 10th anniversary, the company is sharing stories about the students who have completed the program, graduated from college and begun their careers at Travelers.
Travelers EDGE – Summary Video
Ten years ago, Melissa Rodriguez was sitting in her literature class at Capital Community College in Hartford, Connecticut, when a dynamic guest speaker discussed the possibilities of a new career program designed to prepare students for the business world. Inspired by this speech, she applied and was accepted to the first class of what is now the Travelers EDGE program.
Rodriguez, one of seven children, was the first in her family to graduate from college. She'd watched her father and older brother work long hours with family-run businesses, including a pizzeria and a grocery store.
Dreams of a Bright Future
"It's a lot of work," says Rodriguez. "I always knew that I wanted to have a profession, that I wanted to be somebody someday, and then give back."
Now Rodriguez speaks at Capital's classes, sharing how her college internship turned into a career she loves, working full-time in underwriting at Travelers while pursuing an MBA.
Students stop her in the halls of Travelers' downtown Hartford offices, sharing how her words motivated them to apply to the Travelers EDGE program. She marvels at the effect of that initial inspiration rippling through the years.
"I still remember that moment when they said yes to me," says Rodriguez. "I felt like it was my golden ticket, like I'd won the lottery."
Travelers EDGE, By the Numbers
As of December 2016, Travelers EDGE, which stands for Empowering Dreams for Graduation and Employment, has provided direct financial assistance to support 440 scholars and 178 interns, including 43 who have been hired upon graduation. Through internships and other professional development opportunities, the program prepares students for careers in the insurance and financial services industries. Almost half of Travelers EDGE interns have been hired by Travelers upon graduation.
Over the past 10 years, the program has expanded from Hartford to Saint Paul, Minnesota, and Baltimore, Maryland, cities where Travelers has a significant presence. The program raises awareness of higher education and careers within the insurance industry as a possibility for high school students and offers academic scholarships, mentoring and career experience through professional development and internships.
At Travelers, Rodriguez's manager, Kevin Cahill, describes her as dedicated and resourceful, someone who can deftly handle an unexpected project and also find time to mentor student interns.
"She's fully engaged in her work here, and that comes through in everything she does," says Cahill. "She's made the most of the opportunity Travelers EDGE has offered."
More than half of Travelers EDGE Scholars are first-generation college students. Most work during the school year. To help students navigate the challenges of adjusting to college and balancing work and school, students are paired with program managers on campus as well as mentors at Travelers.
"Travelers has a really strong commitment to opening doors to opportunity," says Marlene Ibsen, President and Chief Executive Officer of the Travelers Foundation. "We believe that the strongest investment we can make for our future, and for the community, is in education."
Meet Other Travelers EDGE Students:
Julio Ortiz
One year out of college, Julio Ortiz is a new homeowner and a Travelers employee, pursuing a passion for underwriting, which he enjoys because it allows him to travel and meet different kinds of people.
"Without the Travelers EDGE program, I don't think I would be where I am today," says Ortiz, who was able to graduate from college knowing he had a job lined up. Without having to worry about paying back college loans, he was able to close on a new condo within a year of graduating. Ortiz benefited from Travelers EDGE in high school, where the program introduced him to the possibility of a career in the insurance and financial services industry.
He officially became a Travelers EDGE Scholar as he graduated from high school. Knowing he would be part of Travelers EDGE, Ortiz decided to enroll in general management at Central Connecticut State University, because the major would allow him to learn about all aspects of the business.
Ortiz recalls putting in long hours to balance Travelers EDGE, school and another job. In the summer, he had a full-time internship at Travelers while also working at a nursing home seven days a week. "Travelers EDGE gave me the motivation to work hard and keep moving," he adds. "The best thing about Travelers EDGE was the support the program gave me while at college. It was almost like a family and everyone kept pushing me."
Nicole Ampe
Insurance was far from Nicole Ampe's mind when she started her college career at Metropolitan State University in Saint Paul, Minnesota. The Minnesota native planned on working in human resources, but after an internship at Travelers in the summer of 2013, she was drawn to working in the claims department.
Before she joined Travelers EDGE, she says, "The only thing I knew about auto insurance was that I had it for my car." Now she's an auto damage appraiser, a job she enjoys. Ampe worked as many as three jobs at a time while supporting herself through college. Her goal was to have zero college debt, a promise to herself she was able to keep thanks to the financial support from Travelers.
The first-generation college student now mentors her younger sister, who is starting college and watching her older sister build her career at Travelers.
Jesus Medina
A freshman at the University of Connecticut, Jesus Medina speaks with the composure of a senior. Medina, who is majoring in management information systems, first interned at Travelers the summer before his senior year of high school and plans to intern again this summer. He's still weighing his post-college career options, but knows he's on track.
"When I talk to people here, they're a bit surprised that I have so much more of a plan than other freshmen," Medina says. He credits Travelers EDGE for that. Medina was a junior at Pathways Academy of Technology & Design, a Hartford Public High School, when he learned about the program, and set his sights on the University of Connecticut. "Coming from an inner city, it was a really good opportunity for me to be able to go to school," Medina says. "I always had the idea in my mind that I'd go to college, but Travelers EDGE helped me be able to go to a good school and to make connections."
A Long Way from Afghanistan
A former Marine reflects on how Travelers EDGE has introduced him to a career path in the financial services industry.
As Travelers EDGE celebrates 10 years, a look back at a handful of the program's graduates, who share where they are now and their plans for the future.


text:
Q: Bogachev change of variables theorem. I am reading the Bogachev's change of variable theorem proof. And I am stuck in an argument contained in it:
Let $F:U\subset \mathbb{R}^n\to \mathbb{R}^n$ an injective $C¹$ map. Given $\epsilon>$ there exist $\delta>0$ s.t  $\forall x,y \in U,~\|x-y\|<\delta$ implies
$$
F(x)-F(y)=F^{'}(x)(y-x)+r(x,y)
$$
where $\|r(x,y)\|\leq \epsilon \|x-y\|$.
Here is where I am stucked:
Claim: Let $Q$ be a cube with center $x_0$ and diameter less than $\delta.$ If $|\det F'(x_0)|\leq \sqrt{\epsilon}$ then  we have that
$$
\lambda (L(Q))-\lambda(F(Q))\leq \sqrt{\epsilon}\lambda (Q)
$$
where $L(x)=F^{'}(x_0)(x-x_0)+F(x_0)$ and $\lambda$ is the $n$-dimensional lebesgue measure.
Can someone give me some help?
Comment: I think the argument pass over to give some inferior bound for
$\text{diam}( F(U))$ by using in some way the inequality
$\|F(x)-F(y)\|\geq \|F^{'}(x_0)(x-y)\|-\|r(x,y\|$.

A: I don't know enough measure theory but since $\lambda(L(Q))=\det L \cdot \lambda(Q)$, you could try to prove that $\det L \le \frac{\lambda(F(Q))}{\lambda(Q)} + |\det F'(x_0)|$.

A: $\lambda(L(Q)) - \lambda(F(Q) \leq \lambda(L(Q)) = \lambda(F'(x_0)Q + (F(x_0) - F'(x_0)x_0)) = \lambda(F'(x_0)Q) = |\det F'(x_0)| \lambda(Q) \leq \sqrt{\epsilon}\lambda(Q).$
Where we use shift invariance as well as the scaling property under linear maps of Lebesgue measure, proofs of which can be seen in Folland, Real Analysis, Theorem 2.42 and 2.44 resp.

redpajama_set_name: RedPajamaStackExchange


text:
The English Heritage 'New Model' Programme
Classed as a 'major project' within Government and requiring a complex governance structure and robust stakeholder engagement to ensure its success, the English Heritage 'New Model' initiative was ground-breaking in its ambition.
In the Spring of 2015, the Historic Buildings and Monuments Commission for England, the Government's adviser on the built historic environment and custodian of over 400 sites and monuments in public ownership (known then as English Heritage), split into two separate bodies after having been awarded a one-off capital lump sum of £80m for repairs and enhancements to the National Heritage Collection.
Caroline Crewe-Read, Head of Programme Delivery, in the Boardroom at Holborn Bars, gave insight into the approach taken to this novel, complex and challenging de-merger which resulted, on 1 April 2015, in the establishment of two separate bodies:
Historic England, the public body that looks after England's historic environment by providing expert advice and fulfilling a statutory role as part of the planning system, helping people protect and care for it and helping the public understand and enjoy it,
The English Heritage Trust, a new charity, which is licensed to look after and open to the public the National Heritage Collection of more than 400 historic properties and their collections.
Caroline has worked for Historic England and its predecessor body English Heritage for 13 years, the last seven of which have been in project and programme management. In September 2013 Caroline took on the role of Head of Programme Delivery for the de-merger of English Heritage. Following implementation in April 2015 Caroline was appointed Head of Corporate Projects and Programmes at Historic England. Caroline has a degree in History, a post-graduate degree in Archaeology and professional qualifications including APMP, MSP and PRINCE2.
Ryan Wilcox
Caroline has kindly made her presentation available for viewing.
English heritage new model apm event 28 january 2016 from Association for Project Management
Advanced - Professional
Current practice - Reports & case studies
Bring Brent Home – the story of the Brent decommissioning project so far webinar
Force Atlantic – project managing the adventure of a lifetime webinar
Being Chartered at 25 – 'How I did it' webinar


Lars is noble, is majestic, is our dear deer! It is a geometric wall animal sculpture, inspired on the Caucasian red stag.
• Exclusive decorative design of Dacoris.
• It is made of strong, but light, calabo plywood.
• You will receive it in a DIY puzzle package. Be aware you will enjoy assembling it!
• Glue or nails are not needed for assembling the animals, just a nail or a hanger to hang it to the wall.
Jumbo is our most gentle elephant but is also a mischievous friend! It is a geometric wall animal sculpture, inspired on the African elephant.
•	Exclusive decorative design of Dacoris.
•	It is made of strong, but light, calabo plywood.
•	You will receive it in a DIY puzzle package. Be aware you will enjoy assembling it!
•	Glue or nails are not needed for assembling the animals, just a nail or hanger to hang it to the wall.
Nina is a spirit dreamer, is our beloved mythical unicorn! It is a geometric wall animal sculpture, inspired on the fairy and magical tales.
•	Don't be afraid to paint your unicorn with bright colours, let your children personalize it as they desire!
Red is a real fighter, a loyal friend, a Spanish bull! He comes directly from our country, standing out due to its incredible geometric sculpturic wall design.
Dacoris could not miss one of the most iconic dog breeds and one of the most trendy dogs across the world.
This Dachshund makes the perfect companion at your workplace or home. Either if you miss your beloved dog or you like the shape of this beautiful puppy, you cannot pass on Frankie.


I'm the Guy in Charge of the Butter!
Many people take themselves too seriously. They sometimes think they are better than they really are. When they get a nice job and a good salary, they adopt a swagger. They walk into a restaurant thinking they own the place, and when drinks are slow in arriving, they are vociferous in their disgust.
This situation reminds me of a story that a friend told me, and I would like to share it with you. As it goes, a man ("Showboat") decides to wield his power during dinner at a restaurant with colleagues. He is unhappy that the service is falling short of his expectations.
Showboat: How long ago did we order our drinks?
Colleague: A few minutes ago.
Showboat: Don't these people know that we need our drinks right away? This is ridiculous! I've been coming to this place for years. I've given so much money to this restaurant. I'm going to call the owner and tell him that he is doing a poor job. You would think that they would know me by now. When I walk in, my martini should be waiting for me.
Colleague: Really … he just took the drink order. It is a bit busier tonight. If we give them a couple more minutes, we will have the drinks.
Showboat: A couple minutes … a couple minutes … a couple minutes … no way! I'm far too important to wait that long for my drinks. Think about how long it will take to get my food. My time is worth far more to me. The people around here are hourly workers, so they don't care how long it takes. Look at them! They are walking around with stupid smiles on their faces. This is far from funny to me.
Colleague: Well, Randy … why don't you cut them some slack. I'm sure they will be here soon.
Showboat: Sir, do you know that the butter is missing?
Waiter: Let me get that for you right away.
Showboat: Sir, I don't think you know who I am! Let me tell you. I own two businesses here in town. I have a membership at an exclusive gold club. I frequently travel to Europe, Asia, and Africa. I own one of the biggest houses in this town. That's who I am! When I ask for butter, it's important that I get it right away!
Waiter: Sir, I don't think you know who I am.
Showboat: You got me there. I don't know who you are.
Waiter: I'm the guy in charge of the butter!
What's the point here? Even if you own the biggest house, play golf with the rich, and travel the world, but you must avoid getting a big head. When you do, the guy in charge of the butter can quickly deflate your prominence.


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Kristina Lindhe presented her autumn collection at the Zita cinema. The theme was "Back in the City" and consisted of classic American style in a mix of dressy and casual garments.
EA 4th, F.A.S, FESWA, LazoSchmidl, Louise Körner, Und, Nebel and Séfr Séfr is this year nominees for the Swedish Fashion Talents, a project created to support young design talents.
Inspired by rock legends like Freddie Mercury and David Bowie – Maria Nilsdotter began her AW16 show with a magic ballet performance to .
An imaginary, intellectual eccentrics was the muse behind Nina Granerøds AW16 collection for Fall Winter Spring Summer. Selected materials such as crushed velvet, lace and corduroy creates a rich mix of new wardrobe favorites.
A trip to southern Spain inspired Valerie Aflalo to create Valerie AW16 collection. Feminine silhouettes from the 80s and 90s, interpreted the colors and patterns taken from cracked pebble beaches from the Mediterranean.
Fleetwood Macs "Go Your Own Way" inspired Ida Sjöstedt to a darker side of her aesthetics. Her glamour remains in the tailored pieces and the show ended with a pompous prom dress.
Twin Peaks was the theme of the House of Dagmar's dramatic show. Materials such as leather, fur and ethically manufactured signature knit garments sets the tone for the collection.
A meeting between art, fashion and photography – Filippa K presented the AW 16 collection with the artist Åsa Stenerhags art and the photographer Julia Hetta photos.


text:
Cantonul Randan este un canton din arondismentul Riom, departamentul Puy-de-Dôme, regiunea Auvergne, Franța.

Comune

 Bas-et-Lezat
 Beaumont-lès-Randan
 Mons
 Randan (reședință)
 Saint-André-le-Coq
 Saint-Clément-de-Régnat
 Saint-Denis-Combarnazat
 Saint-Priest-Bramefant
 Saint-Sylvestre-Pragoulin
 Villeneuve-les-Cerfs

Cantoane în Puy-de-Dôme


Dr. Dori Waggoner serves as Dean of the Swinney Conservatory of Music and chair of the Fine Arts Division. Her teaching responsibilities include theory and applied flute. She also coaches chamber ensembles and assists with the band program.
Prior to seeking an advanced degree, Dori spent several years directing bands in the public schools of Missouri. Her students experienced success performing solos and small ensembles at both district and state levels. Concurrently, her middle school and high school bands earned numerous Superior ratings and were consistently awarded top honors at Music in the Parks Festivals. She remains active as a clinician, adjudicator, presenter, and conductor.
Dori has presented music education research and practitioners' clinics at the national MENC conference, Missouri Bandmasters Association Convention, Missouri Music Educators Association Conference, Kansas Bandmasters Association Convention, and Kansas Music Educators Association Conference. Her research interests include error detection skills and pre-service music teacher training. Recently, she was published in both The Instrumentalist and Journal for Research in Music Education.


text:
import React from 'react';
import Header from '@src/components/header/Header';

/**
 * 框架布局
 *
 * @class Layout
 * @extends {React.Component<any>}
 */
class Layout extends React.Component<any> {
	private layoutStyle: any = {
		margin: 20,
		padding: 20,
		border: '1px solid #000'
	};

	/**
	 * render
	 *
	 * @returns {*}
	 * @memberof Layout
	 */
	public render(): any {
		return (
			<div style={this.layoutStyle}>
				<input type="hidden" name="_csrf" value={this.props.content}></input>
				<Header />
				{this.props.children}
			</div>
		);
	}
}

export default Layout;