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Q: Calculating average width of polygon? I'm interested in examining the average width of a polygon that represents the road surface. I also have the road centerline as a vector (which is sometimes not exactly in the center). In this example, the road-centerline is in red, and the polygon is blue:

One brute force approach I have thought of, is to buffer the line by small increments, intersect the buffer with a fishnet grid, intersect the road-polygon with a fishnet grid, calculate the intersected area for both intersection measures and to keep doing this until the error is small. This is a crude approach though, and I'm wondering if there is a more elegant solution. In addition, this would conceal the width of a large road and a small road.
I'm interested in a solution that uses ArcGIS 10, PostGIS 2.0 or QGIS software. I have seen this question and downloaded Dan Patterson's tool for ArcGIS10, but I wasn't able to calculate what I want with it.
I've just discovered the Minimum Bounding Geometry tool in ArcGIS 10 which enables me to produce the following green polygons:

This seems like a good solution for roads that follow a grid, but would not work otherwise, so I am still interested in any other suggestions.

A: Part of the problem is to find a suitable definition of "average width."  Several are natural but will differ, at least slightly.  For simplicity, consider definitions based on properties that are easy to compute (which is going to rule out those based on the medial axis transform or sequences of buffers, for instance).
As an example, consider that the archetypal intuition of a polygon with a definite "width" is a small buffer (say of radius r with squared ends) around a long, fairly straight polyline (say of length L).  We think of 2r = w as its width.  Thus:

*

*Its perimeter P is approximately equal to 2L + 2w;

*Its area A is approximately equal to w L.
The width w and length L can then be recovered as roots of the quadratic x^2 - (P/2)x + A; in particular, we can estimate

*

*w = (P - Sqrt(P^2 - 16A))/4.

When you're sure the polygon really is long and skinny, as a further approximation you can take 2L + 2w to equal 2L, whence

*

*w (crudely) = 2A / P.

The relative error in this approximation is proportional to w/L: the skinnier the polygon, the closer w/L is to zero, and the better the approximation gets.
Not only is this approach extremely simple (just divide the area by the perimeter and multiply by 2), with either formula it doesn't matter how the polygon is oriented or where it is situated (because such Euclidean motions change neither the area nor the perimeter).
You might consider using either of these formulas to estimate average width for any polygons that represent street segments.  The error you make in the original estimate of w (with the quadratic formula) comes about because the area A also includes tiny wedges at each bend of the original polyline.  If the sum of bend angles is t radians (this is the total absolute curvature of the polyline), then really

*

*P = 2L + 2w + 2 Pi t w and

*A = L w + Pi t w^2.
Plug these into the previous (quadratic formula) solution and simplify.  When the smoke clears, the contribution from the curvature term t has disappeared!  What originally looked like an approximation is perfectly accurate for non-self-intersecting polyline buffers (with squared ends).  For variable-width polygons, this is therefore a reasonable definition of average width.

A: Here I show little optimization about @whuber solution, and I'm putting in terms of "buffer width", because it is useful for integrate the solution of a more general problem: Is there a st_buffer inverse function, that returns a width estimation?
CREATE FUNCTION buffer_width(
        -- rectangular strip mean width estimator
    p_len float,   -- len of the central line of g
    p_geom geometry, -- g
    p_btype varchar DEFAULT 'endcap=flat' -- st_buffer() parameter
) RETURNS float AS $f$
  DECLARE
    w_half float;
    w float;
  BEGIN
         w_half := 0.25*ST_Area(p_geom)/p_len;
         w      := 0.50*ST_Area( ST_Buffer(p_geom,-w_half,p_btype) )/(p_len-2.0*w_half);
     RETURN w_half+w;
  END
$f$ LANGUAGE plpgsql IMMUTABLE;

For this problem, the @celenius  question about street width, sw, the solution is
 sw = buffer_width(ST_Length(g1), g2)

where sw is the "average width", g1 the central line of g2, and the street g2 is a POLYGON. I used only the OGC standard library, tested with PostGIS, and solved other serious practical applications with the same buffer_width function.
DEMONSTRATION
A2 is the area of g2, L1 the length of the central line (g1) of g2.
Supposing that we can generate g2 by g2=ST_Buffer(g1,w), and that g1 is a straight, so g2 is a rectangle with lenght L1 and width 2*w, and
    A2 = L1*(2*w)   -->  w = 0.5*A2/L1

It is not the same formula of @whuber, because here w is a half of the rectangle (g2)  width. It is a good estimator, but as we can see by tests (below), is not exact, and the function use it as a clue, to reduce the g2 area, and as a final estimator.
Here we  do not evaluate buffers with "endcap=square" or "endcap=round", that need a sum to  A2  of an area of a point buffer with the same w.
REFERENCES: in a similar forum of 2005, W. Huber explains suchlike and other solutions.
TESTS AND REASONS
For straight lines the results, as expected, are exact. But for other geometries the results can be disappointing.  The main reason is, perhaps, all the model is for exact rectangles, or for geometries that can be approximated to a "strip rectangle". Here a "test kit" for check the limits of this approximation (see wfactor in the results above).
 SELECT *, round(100.0*(w_estim-w)/w,1) as estim_perc_error
    FROM (
        SELECT btype, round(len,1) AS len, w, round(w/len,3) AS wfactor,
               round(  buffer_width(len, gbase, btype)  ,2) as w_estim ,
               round(  0.5*ST_Area(gbase)/len       ,2) as w_near
        FROM (
         SELECT
            *, st_length(g) AS len, ST_Buffer(g, w, btype) AS gbase
         FROM (
               -- SELECT ST_GeomFromText('LINESTRING(50 50,150 150)') AS g, -- straight
               SELECT ST_GeomFromText('LINESTRING(50 50,150 150,150 50,250 250)') AS g,
            unnest(array[1.0,10.0,20.0,50.0]) AS w
              ) AS t,
             (SELECT unnest(array['endcap=flat','endcap=flat join=bevel']) AS btype
             ) AS t2
        ) as t3
    ) as t4;

RESULTS:
WITH RECTANGLES (central line is a STRAIGHT LINE):
         btype          |  len  |  w   | wfactor | w_estim | w_near | estim_perc_error
------------------------+-------+------+---------+---------+--------+------------------
 endcap=flat            | 141.4 |  1.0 |   0.007 |       1 |      1 |                0
 endcap=flat join=bevel | 141.4 |  1.0 |   0.007 |       1 |      1 |                0
 endcap=flat            | 141.4 | 10.0 |   0.071 |      10 |     10 |                0
 endcap=flat join=bevel | 141.4 | 10.0 |   0.071 |      10 |     10 |                0
 endcap=flat            | 141.4 | 20.0 |   0.141 |      20 |     20 |                0
 endcap=flat join=bevel | 141.4 | 20.0 |   0.141 |      20 |     20 |                0
 endcap=flat            | 141.4 | 50.0 |   0.354 |      50 |     50 |                0
 endcap=flat join=bevel | 141.4 | 50.0 |   0.354 |      50 |     50 |                0

WITH OTHER GEOMETRIES (centerline folded):
         btype          | len |  w   | wfactor | w_estim | w_near | estim_perc_error
 -----------------------+-----+------+---------+---------+--------+------------------
 endcap=flat            | 465 |  1.0 |   0.002 |       1 |      1 |                0
 endcap=flat join=bevel | 465 |  1.0 |   0.002 |       1 |   0.99 |                0
 endcap=flat            | 465 | 10.0 |   0.022 |    9.98 |   9.55 |             -0.2
 endcap=flat join=bevel | 465 | 10.0 |   0.022 |    9.88 |   9.35 |             -1.2
 endcap=flat            | 465 | 20.0 |   0.043 |   19.83 |  18.22 |             -0.9
 endcap=flat join=bevel | 465 | 20.0 |   0.043 |   19.33 |  17.39 |             -3.4
 endcap=flat            | 465 | 50.0 |   0.108 |   46.29 |  40.47 |             -7.4
 endcap=flat join=bevel | 465 | 50.0 |   0.108 |   41.76 |  36.65 |            -16.5

 wfactor= w/len
 w_near = 0.5*area/len
 w_estim is the proposed estimator, the buffer_width function.

About btype see ST_Buffer guide, with good ilustratins and the LINESTRINGs used here.
CONCLUSIONS:

*

*the estimator of w_estim is always better than w_near;

*for "near to rectangular" g2 geometries, its ok, any wfactor

*for another geometries (near to "rectangular strips"), use the limit wfactor=~0.01 for 1% of error on w_estim. Up to this wfactor, use another estimator.

Caution and prevention
Why the estimation error occurs?
When you use ST_Buffer(g,w), you expect, by the "rectangular strip model", that the new area added by the buffer of width w is about w*ST_Length(g) or w*ST_Perimeter(g)...  When not, usually by overlays (see folded lines) or by "styling", is when the estimation of average w fault.  This is the main message of the tests.
To detect this problem at any king of buffer, check the behavior of the buffer generation:
SELECT btype, w, round(100.0*(a1-len1*2.0*w)/a1)::varchar||'%' AS straight_error,
                 round(100.0*(a2-len2*2.0*w)/a2)::varchar||'%' AS curve2_error,
                 round(100.0*(a3-len3*2.0*w)/a3)::varchar||'%' AS curve3_error
FROM (
 SELECT
    *, st_length(g1) AS len1, ST_Area(ST_Buffer(g1, w, btype)) AS a1,
    st_length(g2) AS len2, ST_Area(ST_Buffer(g2, w, btype)) AS a2,
    st_length(g3) AS len3, ST_Area(ST_Buffer(g3, w, btype)) AS a3
 FROM (
       SELECT ST_GeomFromText('LINESTRING(50 50,150 150)') AS g1, -- straight
              ST_GeomFromText('LINESTRING(50 50,150 150,150 50)') AS g2,
              ST_GeomFromText('LINESTRING(50 50,150 150,150 50,250 250)') AS g3,
              unnest(array[1.0,20.0,50.0]) AS w
      ) AS t,
     (SELECT unnest(array['endcap=flat','endcap=flat join=bevel']) AS btype
     ) AS t2
) as t3;

RESULTS:
         btype          |  w   | straight_error | curve2_error | curve3_error
------------------------+------+----------------+--------------+--------------
 endcap=flat            |  1.0 | 0%             | -0%          | -0%
 endcap=flat join=bevel |  1.0 | 0%             | -0%          | -1%
 endcap=flat            | 20.0 | 0%             | -5%          | -10%
 endcap=flat join=bevel | 20.0 | 0%             | -9%          | -15%
 endcap=flat            | 50.0 | 0%             | -14%         | -24%
 endcap=flat join=bevel | 50.0 | 0%             | -26%         | -36%

A: If you can join your polygon data to your centerline data (by either spatial or tabular means), then just sum the polygon areas for each centerline alignment and divide by the length of the centerline.

A: I've developed a formula for the average width of a polygon and put it into a Python/ArcPy function. My formula is derived from (but substantially extends) the most straightforward notion of average width that I've seen discussed elsewhere; that is, the diameter of a circle having the same area as your polygon. However, in the question above and in my project, I was more interested in the width of the narrowest axis. Furthermore, I was interested in the average width for potentially complex, non-convex shapes.
My solution was:
(perimeter / pi) * area / (perimeter**2 / (4*pi))
= 4 * area / perimeter

That is:
(Diameter of a circle with the same perimeter as the polygon) * Area / (Area of a circle with the same perimeter as the polygon)

The function is:
def add_average_width(featureClass, averageWidthField='Width'):
    '''
    (str, [str]) -> str

    Calculate the average width of each feature in the feature class. The width
        is reported in units of the feature class' projected coordinate systems'
        linear unit.

    Returns the name of the field that is populated with the feature widths.
    '''
    import arcpy
    from math import pi

    # Add the width field, if necessary
    fns = [i.name.lower() for i in arcpy.ListFields(featureClass)]
    if averageWidthField.lower() not in fns:
        arcpy.AddField_management(featureClass, averageWidthField, 'DOUBLE')

    fnsCur = ['SHAPE@LENGTH', 'SHAPE@AREA', averageWidthField]
    with arcpy.da.UpdateCursor(featureClass, fnsCur) as cur:
        for row in cur:
            perim, area, width = row
            row[-1] = ((perim/pi) * area) / (perim**2 / (4 * pi))
            cur.updateRow(row)

    return averageWidthField

Here is an exported map with the average width (and some other geometry attributes for reference) across a variety of shapes using the function from above:

A: Another solution with approximate medial axis:

*

*Calculate approximate medial axis of the polygon;

*Get length of approximate medial axis;

*Get distance from both ends of axis to polygon's border;

*Sum axis length and distances from step 3 -- it is approximate polygon's length;

*Now you can divide polygon's area by this length and get average width of polygon.

Result will be surely wrong for those polygons where approximate medial axis is not a single continuous line, so you can check it before step 1 and return NULL or something.

Here is example of PostgreSQL function (note: you need to install postgis and postgis_sfcgal extensions):
CREATE FUNCTION ApproximatePolygonLength(geom geometry)
RETURNS float AS $$
    SELECT
        CASE
            /* in case when approximate medial axis is empty or simple line
             * return axis length
             */
            WHEN (ST_GeometryType(axis.axis) = 'ST_LineString' OR ST_IsEmpty(axis.axis))
                THEN axis_length.axis_length
                    + start_point_distance.start_point_distance
                    + end_point_distance.end_point_distance
            /* else geometry is too complex to define length */
            ELSE NULL
        END AS length
    FROM
        LATERAL (
            SELECT
                ST_MakeValid(geom) AS valid_geom
        ) AS valid_geom,
        LATERAL (
            SELECT
                /* `ST_LineMerge` returns:
                 *  - `GEOMETRYCOLLECTION EMPTY`, if `ST_ApproximateMedialAxis` is an empty line (i.e. for square);
                 *  - `LINESTRING ...`, if `ST_ApproximateMedialAxis` is a simple line;
                 *  - `MULTILINESTRING ...`, if `ST_ApproximateMedialAxis` is a complex line
                 *     that can not be merged to simple line. In this case we should return `NULL`.
                 */
                ST_LineMerge(
                    ST_ApproximateMedialAxis(
                        valid_geom.valid_geom
                    )
                ) AS axis
        ) AS axis,
        LATERAL (
            SELECT
                ST_Boundary(valid_geom.valid_geom) AS border
        ) AS border,
        LATERAL (
            SELECT
                ST_Length(axis.axis) AS axis_length
        ) AS axis_length,
        LATERAL (
            SELECT
                ST_IsClosed(axis.axis) AS axis_is_closed
        ) AS axis_is_closed,
        LATERAL (
            SELECT
                CASE WHEN axis_is_closed.axis_is_closed THEN 0
                ELSE
                    ST_Distance(
                        border.border,
                        CASE ST_GeometryType(axis.axis)
                            WHEN 'ST_LineString' THEN ST_StartPoint(axis.axis)
                            /* if approximate medial axis is empty (i.e. for square),
                             * get centroid of geometry
                             */
                            ELSE ST_Centroid(valid_geom.valid_geom)
                        END
                    )
                END AS start_point_distance
        ) AS start_point_distance,
        LATERAL (
            SELECT
                CASE WHEN axis_is_closed.axis_is_closed THEN 0
                ELSE
                    ST_Distance(
                        border.border,
                        CASE ST_GeometryType(axis.axis)
                            WHEN 'ST_LineString' THEN ST_EndPoint(axis.axis)
                            /* if approximate medial axis is empty (i.e. for square),
                             * get centroid of geometry
                             */
                            ELSE ST_Centroid(valid_geom.valid_geom)
                        END
                    )
                END AS end_point_distance
        ) AS end_point_distance;
$$ LANGUAGE SQL;

CREATE FUNCTION ApproximatePolygonWidth(geom geometry)
RETURNS float AS $$
    SELECT
        CASE
            WHEN length IS NULL THEN NULL
            ELSE area.area / length.length
        END AS width
    FROM
        (
            SELECT ApproximatePolygonLength(geom) AS length
        ) AS length,
        (
            SELECT
                ST_Area(
                    ST_MakeValid(geom)
                ) AS area
        ) AS area;
$$ LANGUAGE SQL;

Disadvantage:
This solution will not work with cases when polygon is almost rectangular and human can intuitevely define its length but approximate medial axis has little branches near the edge and thus algorithm returns None.
Example:


text:
Q: Password Maker Python Lists This program is supposed to prompt the user to make a password, however only
certain characters are allowed to be used.
def password(z):
    n=0
    w=0
    a=0
    b=['!','@','#','$','%','^','&','*','?']
    c=['.',',',':',';','[',']','{','}','(',')','<','>','|','~','-
       ','=','+','_']
    for ch in z:
        if any(ch in c for ch in z):
            z=raw_input("Illegal characters. Please try again: ")
            return password(z)
        else:
            if any(ch.isdigit() for ch in z):
                n+=1
            if any(ch in b for ch in z):
                w+=1
            if any(ch.isalpha() for ch in z):
                a+=1
            if n==0 or w==0 or a==0:
                m=raw_input("Please use at least one letter, number, and special character: \n")
                return password(m)
            if n>0 and w>0 and a>0:
                y=raw_input("Please retype password: ")
            if y==z:
                print "Password confirmed"
                break
            else:
                y=raw_input("Not the same password. Please create a new password: ")
                return password(y)

z=raw_input('Enter a password: ')
print password(z)

UPDATE: This now works. I'm however a bit confused as to why it does, since I don't know why I needed to put the any method for ch in b, cause I thought that if ch in b means that if any ch is in the list b. Regardless, it now works.

A: The function returns None, because you have no return statements at all.  None is the default return value.  Your logic is somewhat convoluted, especially the superfluous recursion, but I think you can fix this by simply adding
return z

to the bottom of the function.

FOLLOW-UP
I revisited this ... and your logic appears to have a variety of problems.

*

*Your indentation is faulty near the bottom of the loop; this code won't reach execution.

*int() always returns 0.  I think you want ch.isdigit() here

*You check each character for being 0, then in the "b" list, then in the "c" list ... and as soon as you find all three, you move on to confirming the password.  Is that the logic flow you wanted?

Also ...

*

*Single-letter variable names have very little information.  Use descriptive ones.

*For simple exists / doesn't exist variables, use Boolean, not 0 and 1.  Again, this will make your code easier to read.

*If you change b and c to strings, the code will be easier to read, and your in statements will still work.

A: The reason your function returns None, is because your function doesn't return anything when it is successful.
Also, even if you did add a return statement, your check for integers is not correct. one correct way to check this would be ch.isdigit()

redpajama_set_name: RedPajamaStackExchange


text:
NCBI CID
Disease relevance of Chlorobiocin
High impact information on Chlorobiocin
Chemical compound and disease context of Chlorobiocin
Biological context of Chlorobiocin
Associations of Chlorobiocin with other chemical compounds
Gene context of Chlorobiocin
Analytical, diagnostic and therapeutic context of Chlorobiocin
Chemical Compound Review:
Chlorobiocin [6-[8-chloro-2-hydroxy-3-[[4- hydroxy-3-(3...
Westrich, L. et al., Galm, U. et al., Freitag, A. et al., Freitag, A. et al., Tsai, F.T. et al., et al.
Lafitte, Lamour, Tsvetkov, Makarov, Klich, Deprez, Moras, Briand, Gilli,
In the present study, the prenyltransferase involved in the biosynthesis of this moiety was identified from the clorobiocin producer (Streptomyces roseochromogenes), overexpressed, and purified [1].
Clorobiocin was the most active compound both against E. coli DNA gyrase in vitro and against bacterial growth [2].
Twenty-eight novel clorobiocin derivatives obtained from mutasynthesis experiments were investigated for their inhibitory activity towards Escherichia coli DNA gyrase and for their antibacterial activities towards clinically relevant gram-positive and gram-negative bacteria in comparison to novobiocin and clorobiocin [2].
Antibacterial activity tests against Bacillus subtilis showed that novclobiocin 109 and novclobiocin 110 have antibacterial activities about eight times less than that of clorobiocin, whereas novclobiocin 104 showed no activity under the test conditions [3].
CloQ from the clorobiocin biosynthetic gene cluster in Streptomyces roseochromogenes DS 12976 has recently been identified as a 4-hydroxyphenylpyruvate-3-dimethylallyltransferase [4].
Their chemical structures contain amide bonds, formed between an aminocoumarin ring and an aromatic acyl component, which is 3-dimethylallyl-4-hydroxybenzoate in the case of novobiocin and clorobiocin [5].
By gene inactivation, clo-hal was identified as the gene of the halogenase responsible for the introduction of the chlorine atom of clorobiocin [6].
Novobiocin and clorobiocin are gyrase inhibitors produced by Streptomyces strains [7].
When the 5-methylpyrrolyl-2-carboxyl-thioester of CouN1 is the cosubstrate, the in vitro product differs from clorobiocin only in a CH3 for Cl group change on the coumarin ring [8].
Novobiocin, coumermycin A1, and clorobiocin, structurally related compounds that antagonize the B subunit of the essential bacterial enzyme DNA gyrase, were compared with 18 of their analogs for the inhibition of Escherichia coli DNA gyrase supertwisting activity in vitro and of bacterial multiplication [9].
Three new antibiotics, vanillobiocin, isovanillobiocin and declovanillobiocin, were isolated from the culture broth of a cloQ-defective mutant of the clorobiocin producer Streptomyces roseochromogenes, which is blocked in the biosynthesis of the prenylated 4-hydroxybenzoic acid moiety of clorobiocin [10].
Metabolic engineering of the heterologous production of clorobiocin derivatives and elloramycin in Streptomyces coelicolor M512 [11].
To understand the difference in affinity, in order that this information might be exploited in rational drug design, the crystal structure of the 24-kDa GyrB fragment in complex with clorobiocin was determined to high resolution [12].
Although a derivative of ColE1-pBR322 was effectively cured by clorobiocin, the ColE1 plasmid was resistant to its effect [13].
In this study, the genes cloN1 and cloN7 were deleted separately from a cosmid containing the complete clorobiocin cluster [14].
CloN6, a novel methyltransferase catalysing the methylation of the pyrrole-2-carboxyl moiety of clorobiocin [3].
Correlation of hydrophobicity with protein binding for clorobiocin analogs [15].
Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters [16].
The biosynthetic gene clusters of the gyrase inhibitors coumermycin A(1) and clorobiocin contain two different resistance genes (gyrB(R) and parY(R)) [17].
In contrast to the results obtained with clorobiocin, inhibition of cell division by the beta-lactam antibiotic cefuroxime did not cause any detectable disturbance in the rate of synthesis of either inner or outer membrane protein [18].
However, unlike other inhibitors of deoxyribonucleic acid synthesis, clorobiocin failed to induce the synthesis of protein X, the recA gene product [19].
Clorobiocin, an inhibitor of the gyrB subunit of DNA gyrase, was used for the curing of some Escherichia coli plasmids [13].
Antimicrobial and DNA gyrase-inhibitory activities of novel clorobiocin derivatives produced by mutasynthesis [2].
In this work, we obtained the crystal costructures of the natural coumarin clorobiocin and a synthetic analogue with the 24 kDa gyrase fragment [20].
Metabolic engineering of aminocoumarins: inactivation of the methyltransferase gene cloP and generation of new clorobiocin derivatives in a heterologous host [21].
Moreover, to understand the differences in energetics of binding of clorobiocin and novobiocin to the protein, the results from isothermal titration calorimetry are also presented [12].
However, sequence analysis of the clorobiocin biosynthetic gene cluster did not reveal a gene with sequence similarity to the SAM-dependent methyltransferases that could be assigned to this reaction [3].
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics [22].
Crystallization and preliminary X-ray analysis of the aromatic prenyltransferase CloQ from the clorobiocin biosynthetic cluster of Streptomyces roseochromogenes [23].
CloQ, a prenyltransferase involved in clorobiocin biosynthesis. Pojer, F., Wemakor, E., Kammerer, B., Chen, H., Walsh, C.T., Li, S.M., Heide, L. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
Antimicrobial and DNA gyrase-inhibitory activities of novel clorobiocin derivatives produced by mutasynthesis. Galm, U., Heller, S., Shapiro, S., Page, M., Li, S.M., Heide, L. Antimicrob. Agents Chemother. (2004) [Pubmed]
CloN6, a novel methyltransferase catalysing the methylation of the pyrrole-2-carboxyl moiety of clorobiocin. Westrich, L., Heide, L., Li, S.M. Chembiochem (2003) [Pubmed]
CloR, a bifunctional non-heme iron oxygenase involved in clorobiocin biosynthesis. Pojer, F., Kahlich, R., Kammerer, B., Li, S.M., Heide, L. J. Biol. Chem. (2003) [Pubmed]
In vitro and in vivo production of new aminocoumarins by a combined biochemical, genetic, and synthetic approach. Galm, U., Dessoy, M.A., Schmidt, J., Wessjohann, L.A., Heide, L. Chem. Biol. (2004) [Pubmed]
Clorobiocin biosynthesis in Streptomyces: identification of the halogenase and generation of structural analogs. Eustáquio, A.S., Gust, B., Luft, T., Li, S.M., Chater, K.F., Heide, L. Chem. Biol. (2003) [Pubmed]
Structure-Activity Relationships of Aminocoumarin-Type Gyrase and Topoisomerase IV Inhibitors Obtained by Combinatorial Biosynthesis. Flatman, R.H., Eustaquio, A., Li, S.M., Heide, L., Maxwell, A. Antimicrob. Agents Chemother. (2006) [Pubmed]
Installation of the pyrrolyl-2-carboxyl pharmacophore by CouN1 and CouN7 in the late biosynthetic steps of the aminocoumarin antibiotics clorobiocin and coumermycin A1. Garneau-Tsodikova, S., Stapon, A., Kahne, D., Walsh, C.T. Biochemistry (2006) [Pubmed]
Effects of novobiocin, coumermycin A1, clorobiocin, and their analogs on Escherichia coli DNA gyrase and bacterial growth. Hooper, D.C., Wolfson, J.S., McHugh, G.L., Winters, M.B., Swartz, M.N. Antimicrob. Agents Chemother. (1982) [Pubmed]
New aminocoumarin antibiotics from a cloQ-defective mutant of the clorobiocin producer Streptomyces roseochromogenes DS12.976. Freitag, A., Galm, U., Li, S.M., Heide, L. J. Antibiot. (2004) [Pubmed]
Metabolic engineering of the heterologous production of clorobiocin derivatives and elloramycin in Streptomyces coelicolor M512. Freitag, A., M??ndez, C., Salas, J.A., Kammerer, B., Li, S.M., Heide, L. Metab. Eng. (2006) [Pubmed]
The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin. Tsai, F.T., Singh, O.M., Skarzynski, T., Wonacott, A.J., Weston, S., Tucker, A., Pauptit, R.A., Breeze, A.L., Poyser, J.P., O'Brien, R., Ladbury, J.E., Wigley, D.B. Proteins (1997) [Pubmed]
Curing effect of clorobiocin on Escherichia coli plasmids. Cejka, K., Holubová, I., Hubácek, J. Mol. Gen. Genet. (1982) [Pubmed]
Acyl transfer in clorobiocin biosynthesis: involvement of several proteins in the transfer of the pyrrole-2-carboxyl moiety to the deoxysugar. Freitag, A., Wemakor, E., Li, S.M., Heide, L. Chembiochem (2005) [Pubmed]
Correlation of hydrophobicity with protein binding for clorobiocin analogs. Coulson, C.J., Smith, V.J. Journal of pharmaceutical sciences. (1980) [Pubmed]
Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters. Eustáquio, A.S., Gust, B., Galm, U., Li, S.M., Chater, K.F., Heide, L. Appl. Environ. Microbiol. (2005) [Pubmed]
Identification of a topoisomerase IV in actinobacteria: purification and characterization of ParYR and GyrBR from the coumermycin A1 producer Streptomyces rishiriensis DSM 40489. Schmutz, E., Hennig, S., Li, S.M., Heide, L. Microbiology (Reading, Engl.) (2004) [Pubmed]
Envelope protein synthesis and inhibition of cell division in Escherichia coli during inactivation of the B subunit of DNA gyrase. Herrero, E., Fairweather, N.F., Holland, I.B. J. Gen. Microbiol. (1982) [Pubmed]
Inhibition of deoxyribonucleic acid gyrase: effects on nucleic acid synthesis and cell division in Escherichia coli K-12. Fairweather, N.F., Orr, E., Holland, I.B. J. Bacteriol. (1980) [Pubmed]
DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose. Lafitte, D., Lamour, V., Tsvetkov, P.O., Makarov, A.A., Klich, M., Deprez, P., Moras, D., Briand, C., Gilli, R. Biochemistry (2002) [Pubmed]
Metabolic engineering of aminocoumarins: inactivation of the methyltransferase gene cloP and generation of new clorobiocin derivatives in a heterologous host. Freitag, A., Rapp, H., Heide, L., Li, S.M. Chembiochem (2005) [Pubmed]
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics. Pojer, F., Li, S.M., Heide, L. Microbiology (Reading, Engl.) (2002) [Pubmed]
Crystallization and preliminary X-ray analysis of the aromatic prenyltransferase CloQ from the clorobiocin biosynthetic cluster of Streptomyces roseochromogenes. Keller, S., Pojer, F., Heide, L., Lawson, D.M. Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. (2006) [Pubmed]

redpajama_set_name: RedPajamaCommonCrawl


Enjoy opportunities for quiet contemplation, fellowship, and faith building at various events and retreats designed to nurture your spiritual side.
The Ignatian Center provides many opportunities to encounter the Spiritual Exercises of St. Ignatius of Loyola and other forms of Christian spirituality. We also celebrate the inter-religious nature of our community with programs representing multiple faith traditions and practices.
Part of the Ignatian Center, the Bannan Institutes are yearlong thematic programs that address matters of significance within the Jesuit, Catholic intellectual tradition, foster an ethic of dialogue among persons of diverse religious and philosophical commitments, and facilitate opportunities for interdisciplinary exchange across the University and broader community.
The Jesuit Retreat Center of Los Altos offers a full schedule of retreat opportunities.
Here is your opportunity to experience firsthand April in Paris on an exclusive 10-day Jesuits West Pilgrimage. This trip will explore the heart of Paris and nearby environs, providing a blend of beauty, spiritual nourishment, fine food and relaxing touring - while staying in one of the finer hotels in Paris with convenient Metro access. Mass will be celebrated daily. To discover more about this amazing opportunity, visit the Jesuit West website.
To learn about retreats or other spiritual offereings either in your area or online, please contact Sarah Bonini in Alumni Relations.


text:
'The Hunter of the Dark' by Donato Carrisi
Published by Abacus (Little Brown),
5 November 2015.
The Hunter of the Dark is a priest named Marcus who belongs to ancient Italian team within the Vatican called the Penienzieri. They are trained in detecting evil that no one else can see.
A murderer is at large in Rome who kills couples and subjects them to strange rituals bordering on the occult.
Sandra is a police photographer and she teams up with Marcus whom she knew previously to set about catching the "Monster" as the killer becomes known.
Investigations lead them back many years to an Institute for children who had committed terrible crimes. There then begins the job of tracing all the children and staff , leading them into many narrow escapes as they unveil the evil character responsible for the ritual killings.
Also what is the meaning of the image of a man with a wolf's head which appears at the scene of some of the murders?
Just as they think they are getting nearer the truth, something leads them in another direction, making for a gripping read which races along at a break neck speed. Also running parallel with the main story is the mystery of the discovery of the dismembered body of a nun in the Vatican garden a year earlier. Marcus found her body and is determined to find the killer and wonders if it is at all connected to the later murders.
What a great book, I had real trouble putting it down. The pace never lets up and one surprise after another actually made me gasp out loud. I love Rome and was transported there so good is the description.
Very interesting is the Author's note at the back. The penitenziere does actually exist and subjects mentioned in the book were based on reality. Although, obviously as he says Donato Carrisi "took liberties" with them to produce a story. A really fantastic read.
Reviewer: Tricia Chappell
Donato Carrisi was born in 1973 and studied law and criminology. Since 1999 he has been working as a TV screenwriter. The Whisperer, Carrisi's first novel, won five international literary prizes, has been sold in nearly twenty countries, and has been translated into languages as varied as French, Danish, Hebrew and Vietnamese. Carrisi lives in Rome.
Tricia Chappell. I have a great love of books and reading, especially crime and thrillers. I play the occasional game of golf (when I am not reading). My great love is cruising especially to far flung places, when there are long days at sea for plenty more reading! I am really enjoying reviewing books and have found lots of great new authors.
Posted by Lizzie at 17:45 No comments:
'Cat Among the Herrings' by L C Tyler
Published by Allison & Busby,
18 February 2016.
The village of West Wittering was burying the last of the Paghams, a family, the rector said had for centuries been significant landowners in the area. That the family fortunes had in recent years declined through gambling, drinking and bribery, he glossed over. Robin Pagham had met a tragic end when out sailing. "Probably drunk" mused the congregation. However, it appeared that Robin's fiancée Catrina did not share the general view, as just as they were all ready to take their leave of the church and head for refreshment at the wake, Catrina lifted her veil and surveying the congregation declared: 'One of you bastards murdered Robin, and I'm going to have your arse.'
At the wake Ethelred Tressidor funds himself buttonholed by Catrina to find out who killed Robin, but he politely refuses. However, when taxed by journalist Tom Gittings, who reveals that his family and the Paghams have lived side by side as it were for centuries, and asks Ethelred to look into the murder of his ancestor John Gittings, he is intrigued. After all, there might be a book in it.
When Ethelred's former agent Elsie Thirkettle gets wind of a possible murder investigation in the village of West Wittering, she wastes no time in scheduling a visit. While Elthelred proceeds to investigate the murder of John Gittings, Elsie pursues her own investigations, with comic results.
Despite their current estrangement it was joy to visit again with Elthelred and Elsie. An intriguing murder, interspersed with the life of a literary agent. All those rejection letters to write, to point budding authors in the right direction with encouragement and kindness. And to help one's PA to understand irony.
I loved this book. And heartily recommend it.
Reviewer: Lizzie Hayes
L. C. Tyler was born in Southend, Essex, and educated at Southend High School for Boys, Jesus College Oxford and City University London. After university he joined the Civil Service and worked at the Department of the Environment in London and Hong Kong. He then moved to the British Council, where his postings included Malaysia, Thailand, Sudan and Denmark.
Since returning to the UK he has lived in Sussex and London, and was Chief Executive of the Royal College of Paediatrics and Child Health for eleven years. He is now a full time writer. His first novel, The Herring Seller's Apprentice, was published by Macmillan in 2007, followed by A Very Persistent Illusion, Ten Little Herrings, The Herring in the Library and Herring on the Nile. The first book in a new historical series, A Cruel Necessity, was published by Constable and Robinson in November 2014. The follow up is A Masterpiece of Corruption and was published in January 2016.
http://www.lctyler.com/
'Hester and Harriet' by Hilary Spiers
Published by Allen & Unwin,
Theft, people-trafficking, manufacturing illegal drugs, car chases: typical ingredients of a fast-paced thriller, wouldn't you say?
How about knitting, cooking, bridge and the cutest, best-behaved baby that ever drew breath?
In Hester and Harriet, Hilary Spiers manages to include all of the above, with hardly a policeman in sight, give or take the odd village bobby and a raid on a cannabis farm that takes place off-stage. The eponymous characters are sisters, both widowed, formerly a senior local government officer and comprehensive school teacher, enjoying a peaceful retirement in a rural village; the most excitement in their lives is the occasional skirmish with another vehicle on account of Harriet's terrible driving.
Then one Christmas they find themselves rescuing Daria, a young eastern European woman, and her baby Milo, who they discover sleeping in a bus shelter. Shortly afterwards Ben, their teenage nephew, arrives on the doorstep in search of sanctuary from his over-protective parents – and Hester and Harriet's quiet existence is set to become a lot more interesting.
As Daria's unfortunate story unfolds, village life goes on, though not quite as normal. There's gossip over an afternoon of bridge regarding a dispute between a snooty neighbour and the local philanderer turned property developer. Finbar the highly educated tramp finds himself involved in a dispute with a shady character. The vicar's wife starts behaving quite out of character. And Ben, a typical fifteen-year-old, acne-ridden, school-phobic and welded to his mobile phone, reveals hidden depths.
Hester, Harriet, Daria and Ben are rounded, believable characters: ordinary people caught up in extraordinary circumstances. Both the village background and the supporting characters are two-dimensional and just a little larger than life: do-gooders Isabelle and George, opinionated Peggy, wide-boy Teddy, a tweedy solicitor, an avuncular desk sergeant, a distinctly seedy private detective. There's even a martinet of a hospital sister for good measure – but it all works in the context of a gentle, humorous narrative in which two ladies of a certain age discover that there's a big, bad world outside their cosy sitting room, and that they quite enjoy the stimulation it provides. And of course it all turns out fine in the end.
The result is an easy read, comforting in the face of the real big, bad world, beautifully written and perfectly pitched.
Reviewer: Lynne Patrick
Hilary Spiers is a novelist, award-winning short story writer and playwright. She enjoys writing about ordinary women in extraordinary circumstances. Hilary lives in the finest stone town in England, with her husband and their neurotic cat Lola. When she isn't writing (which she is most of the time), she is directing, performing or cooking up a storm. Pies are a speciality.
www.hilaryspiers.co.uk
Lynne Patrick has been a writer ever since she could pick up a pen, and has enjoyed success with short stories, reviews and feature journalism, but never, alas, with a novel. She crossed to the dark side to become a publisher for a few years, and is proud to have launched several careers which are now burgeoning. She lives on the edge of rural Derbyshire in a house groaning with books, about half of them crime fiction.
Brit Noir: The Pocket Essential Guide to the Crime Fiction, Film and TV of the British Isles by Barry Forshaw.
Published by Pocket Essentials,
Forshaw has followed his previous Nordic Noir and Euro Noir with this similar format volume on British crime. This handy book is subtitled "A definitive investigation of the contemporary crime field", and that's a well-earned description. In his introduction, Forshaw speaks of a 'new Golden Age' of crime, and the variety of genres, detectives, themes and authors he then gives details of certainly bear that out. He's interpreted 'noir' loosely to include contemporary writers he feels meet his criteria of the key four elements: strong plotting, literate, adroit writing, complex characterisation and vividly evoked locales. This means non-noir writers like McCall Smith and other 'cosies' are included, so it is a real snapshot of crime writing in Britain today. The only crime genre not included is historical crime, although a number of writers who are usually historical are included for their contemporary novels.
The guide is roughly organised by region, so if you enjoy researching your favoured holiday spot with a look at their crime scene, you can do that. However, as Forshaw points out, writers like McDermid and Cleeves are known for several locations, so the easiest way to find a particular author is through the index. All our favourites are here, along with many less well-known (I'm honoured to be included). Each author is then given a paragraph describing the work, the series detective, locale, writing strengths, and a recommendation of a representative book. These paragraphs are descriptions, rather than reviews, as Forshaw points out in his introduction, but he can't help his enthusiasm breaking through when he talks of his particular favourites. England is divided into regions, with Wales and the Borders part of this section, and Scotland and Ireland each have a section of their own. The Irish section includes the whole of Ireland, because, as Forshaw says, he wanted to celebrate as many interesting and talented writers as he could. This is followed by 'A World Elsewhere', with British writers who set their novels abroad. Finally, there's a list of films and TV series, with a paragraph of description of each.
A must-have for crime fans: for reminding yourself about old favourites, for finding new authors, and for that 'What shall we watch?' moment as you contemplate settling down on the sofa for an exciting evening of TV. Highly recommended.
Reviewer: Marsali Taylor
Barry Forshaw's latest books are British Crime Film and Death in a Cold Climate: A Guide to Scandinavian Crime Fiction. Other work includes British Crime Writing: An Encyclopedia, The Rough Guide to Crime Fiction and Guns for Hire: The Modern Adventure Thriller, along with books on Italian cinema and the first biography of Stieg Larsson. His next books are British Gothic Cinema and a study of Thomas Harris and The Silence of the Lambs. He writes for various newspapers, edits Crime Time, and broadcasts for ITV and BBC TV documentaries. He has been Vice Chair of the Crime Writers' Association.
Marsali Taylor grew up near Edinburgh, and came to Shetland as a newly-qualified teacher. She is currently a part-time teacher on Shetland's scenic west side, living with her husband and two Shetland ponies. Marsali is a qualified STGA tourist-guide who is fascinated by history, and has published plays in Shetland's distinctive dialect, as well as a history of women's suffrage in Shetland. She's also a keen sailor who enjoys exploring in her own 8m yacht, and an active member of her local drama group. Marsali also does a regular monthly column for the Mystery People e-zine.
Brit Noir: The Pocket Essential Guide to the Crime...
Deadly Duos: Partners and Sidekicks
'Point of Control' by L.J. Sellers
'Quick and the Dead' by Susan Moody
'Rain Dogs' by Adrian McKinty
'The Woman Who Ran' by Sam Baker
'French Concession' by Xiao Bai
'The Hand that Feeds You' by A J Rich
'NightBlind' by Ragnar Jónasson
'The Corruption of Chastity'Killing Sisters Book 2...
'The Powder Man' by Paul Youlden
Robin Forsythe (1879-1937)
'Echoes of Justice' by J. J. Franklin
'The Fall' by John Lescroart
'The House of Wolfe' by James Carlos Blake
'Goodbye to the Dead' by Brian Freeman
A Life of Crime: What's the Appeal of Crime Writing?
'The Chelsea Strangler' by Susanna Gregory
'Scream, You Die' by Michael Fowler
Debut Authors: An Infusion of Fresh Blood - Friday...
'Abigale Hall' by Lauren Forry
'The Starlings & Other Stories' A Murder Squad and...
'A Stranger's House' by Clare Chase
Forgotten Authors
'Spare me the Truth' by C J Carver
'Thin Ice' by Quentin Bates
'Kill Me Again' by Rachel Abbott
Richard Creasey talks about his father's work
'A Coin for the Hangman' by Ralph Spurrier


text:
RSpec.shared_examples 'a claim journeys query' do
  describe '#prepare' do
    subject(:prepare) { instance.prepare }

    context 'when journeys function does not exist' do
      before do
        ActiveRecord::Base.connection.execute(instance.send(:drop_journeys_func))
      end

      specify 'function does not exist prior to call' do
        expect(instance.send(:journeys_func_exists?)).to be false
      end

      it 'creates the journeys function' do
        prepare
        expect(instance.send(:journeys_func_exists?)).to be true
      end
    end

    context 'when journeys function already exists' do
      before do
        allow(Settings).to receive(:replace_journeys_func?).and_return(replace_flag)
        ActiveRecord::Base.connection.execute(instance.send(:create_journeys_func))
        allow(instance).to receive(:recreate_journeys_func)
      end

      let(:replace_flag) { false }

      specify 'function exists prior to call' do
        expect(instance.send(:journeys_func_exists?)).to be true
      end

      context 'with replace flag false' do
        let(:replace_flag) { false }

        it 'does not recreate function' do
          prepare
          expect(instance).not_to have_received(:recreate_journeys_func)
        end
      end

      context 'with replace flag true' do
        let(:replace_flag) { true }

        it 'recreates function' do
          prepare
          expect(instance).to have_received(:recreate_journeys_func).once
        end
      end
    end
  end

  describe '#journeys_query' do
    subject(:journeys_query) { instance.journeys_query }

    it { is_expected.to be_instance_of(String) }
  end
end

redpajama_set_name: RedPajamaGithub


text:
DARK ESSENCE RECORDS ANNOUNCES DETAILS OF NEW ALBUM FROM ATROX
Atrox, News
Dark Essence Records have today announced details of the upcoming album from one of their latest signings, ATROX. Set for release on the 8th September, and titled "Monocle", this will be the sixth full-length studio album from the veteran Norwegians.
With "Monocle", the first album from the band since 2008's "Binocular", ATROX are back stronger than ever, having fine tuned their sound so that what was once an atmospheric mix of Death and Doom Metal has become much more progressive, experimental and industrial. It is an album that shows a darker side to the band, with more epic and atmospheric elements than before. Consolidating the unique ATROX sound within the album are catchy and upbeat sections.
Artwork for "Monocle" is by Rune Folgerø and Erik Paulsen. Tracklisting is as follows:
1. Mass
3. Heat
4. Finger
5. Suicide Days
6. For We Are Many
7. Movie
8. Target
Today's ATROX lineup comprises Rune Folgerø on Vocals, viNd on Guitars, Rune Sørgård on Guitars & Technology, Tor Arne Helgesen on Drums and Erik Paulsen on Bass, and they recently had some very interesting things to say about "Monocle":
"Monocle" is our darkest album so far. During the process of creating and recording it we explored, and were exposed to, our darker selves, and what we encountered during this process almost killed us. It left us in a dystopian vacuum and all worn out, but with one hell of a piece of music to present to the world.
"Musically speaking "Monocle" contains poisons that'll blind you, and poisons that'll open your eyes.
As William Gibson says in his novel "Neuromancer": "The future is already here. It's just unevenly distributed."
More information about ATROX can be found on the band's website at http://www.atrox.no/ or on Facebook at https://www.facebook.com/atrox.no
The time-lapse video of Finnmark and North Troms (Norway), photographed and edited by Randulf Valle and using ATROX's Den Store Hvite Stillhet / The Great White Silence as a soundtrack can be seen below and at https://youtu.be/awDolWWpcJM
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You Are Here: Home » National News » Confirmed: Black Lives Matter, but not as much as White Lives!
Confirmed: Black Lives Matter, but not as much as White Lives!
While homicide is the leading cause of premature death among Blacks, it is the 12th leading cause among whites. Yet, there is very little research devoted to Black homicides, causing many to conclude that Black lives matter but not as much as white lives.
A recent study evaluated the leading causes of death in 2015 by race in the United States. Researchers found that Blacks accounted for 20 percent of the nearly 21.4 million potential years of life lost in 2015 even though they make up only 13 percent of the U.S. population. Further, they found that birth defects and suicides occur among Blacks more than ten years earlier than whites. Yet funding for research on premature deaths focuses on whites, not Blacks.
For example, in 2015 researchers found that heart disease is the leading cause of potential years of life lost among whites. This research was supported by 341 grants and almost 600 publications. On the other hand, homicide, the leading cause of premature death among Blacks, received support by only a few grants and publications.
Study author Molly Rosenberg points out another inequality regarding premature deaths among Blacks compared to whites. Very often, the "loss of human potential can push families into poverty and societies toward heightened inequality," she stated. Black families are more inclined to feel the affects of the loss of a family member to a greater degree, pushing them further into poverty.
Since homicide is the leading cause of death among Blacks, it deserves more funding for public health research. Otherwise, we are perpetuating "a system that disadvantages the health of Black Americans." Black lives matter! Period.


I've seen a few articles over the past week in which Clinton supporters said they would not support Obama if he won the Democratic primary. And, I've had conversations with Obama supporters who said the same about Clinton. For both (and for full disclosure, I'm an Obama supporter), I am shocked. How could you not support the other if s/he won? If for no other reason than that Justice Stevens is 88 years old.
In past elections, the prospect of a change on the Supreme Court was important. But, losing Roe and other progressive precedents has never been as possible as it is now. In the recent past, we had Justices O'Connor and Kennedy on the Court as the "swing" votes. But this is the first Presidential election since O'Connor retired, which means we now have four solid conservative votes in Chief Justice Roberts and Justices Scalia, Thomas, and Alito. As I've written about, Kennedy is not as much of a swing Justice as some make him out to be, but he is, at this point, an important vote for gay rights (in some circumstances) and for the basic right to choose (albeit with restrictions).
At 88, Justice Stevens is the oldest member of the Supreme Court. I wouldn't put much money on the chances of him making it as a member of the Court to 2012, the next presidential election. So, in all likelihood, he will need to be replaced during the next President's term. If McCain is the President, he has given every indication, through his votes and his speeches, that he would appoint another Justice in the Alito/Roberts conservative mold. With that Justice replacing Stevens, the McCain-appointed conservative would be the fifth vote for a young, solid conservative majority on the Court. Roe, Lawrence, Romer, Gratz, VMI, and many other progressive decisions would be at serious risk.
But, if Clinton or Obama is President, whatever you think of their general merit compared to one another, Justice Stevens' replacement would undoubtedly not be a young conservative. With a likely more solidified Democratic majority in the Senate, President Clinton or President Obama would protect the progressive Supreme Court that has become central to our modern constitutional order.
If for no other reason, whichever Democratic candidate wins this primary has my vote. And s/he should have yours too.
I do understand your reasoning, and I probably will vote, even though for various reasons I can't stand or trust Obama. It's really a case of McCain being by far the worst of two men I can't stand, and the Bush presidency is enough of a lesson for me to know I should at least try to vote.
That said, I hate it when people get hostile about people not voting because they don't like the candidate. "Vote for the Democrat! What are you, crazy?" I think the beauty of our system, flawed though it may be, is that we have a choice. I know staying home is a vote for the winner, but some of us can't in good conscious vote for someone we strongly oppose. It's also very difficult for some people to vote. Like I said, I'm going to try, but I'm not particularly enthusiastic, and when I think about trying to get to my polling place – in a season where it very well may be snow and ice in Iowa, when I have to run across a very dangerous highway with no pedestrian crosswalks, not to mention the fact that I'm a law student and work twenty hours a week and the hour it takes me to walk there and back is an hour of precious sleep lost – it just makes me feel defeated. If I were excited about the candidate, it'd be different, but the way I see it whether Obama or McCain, I'm not going to like the 2008 administration.


text:
Hollywood Release: Django Unchained
Apr 12, 2013 09:58 IST
Quentin Tarantino's Oscars awarded and highly anticipated film Django Unchained is all set to release in India. Here's a look
Jamie Foxx plays Django, a plantation slave in the action-packed film Django Unchained.
Christoph Waltz (left) who won the Oscar award for Best Supporting actor plays Dr King Schultz, a bounty hunter who teams with Django (Jamie Foxx) to free his wife in Django Unchained.
Django (Jamie Foxx) with Dr King Schultz (Christoph Waltz) on a quest to save Django wife.
Leonardo DiCaprio plays the ruthless plantation owner Calvin Candie who captures Django's wife in the film.
Christoph Waltz (Dr. King Schultz) and Jamie Foxx (Django) in a still from Django Unchained.
Django (Jamie Foxx) with Amerigo Vessepi played by Franco Nero (who played Django in the original 1966 film and its 1987 sequel) in a still from Django Unchained.
Leonardo DiCaprio as the heartless Calvin Candie in a still from Django Unchained.
Django Unchained director Quentin Tarantino who won Oscar for Best Original Screenplay has also played a role in the film as an employee at The LeQuint Dickey Mining Co.


text:
Why are doctors using PDAs?
by John Fuller
PDA Use in Health Care
PDAs give health care professionals access to loads of medical information on the spot.
Jose Luis Pelaez/Getty Images
It's important to remember that personal digital assistants are essentially like tiny, handheld laptop computers. Although they typically don't have as much memory as computers, they're powered by microprocessors and run on an operating system, and advanced PDAs run very close to laptop capability. Despite the perceived lack of memory available, PDAs can hold anywhere from 16 to 128 MB of data on their systems. On top of this, owners with newer models have the option to add even more memory with the help of expansion cards, which can add as much as 512 MB of memory. Even though you probably can't put your entire iTunes library onto a PDA, you can use one to store a lot of smaller files like PDFs, which contain a wealth of information.
Doctors, nurses and most professional health care workers have found this fact extremely beneficial in their practice, and hospitals, doctor's offices and pharmacies have quickly adapted to the benefits of PDA technology over the past decade. By 2003, for instance, more than 50 percent of doctors were using handheld computers in some form during their daily activities, while an even larger percentage of residents and students used them and showed proficiency [source: Palm Infocenter].
Health care providers rely on a staggering amount of information to help patients. Doctors use reference material from books or print off data from larger computers to ensure accuracy and provide diagnosis, while pharmacists do the same to look up drug information. Seeking out this type of information takes time and wastes resources if it involves printing, and because of the constant need to update, books can become outdated in a matter of weeks when new discoveries are made.
If doctors and nurses use PDAs, however, they can carry with them large tomes of medical reference which they can access on the spot. This allows them to make quicker decisions regarding diagnoses and medicine prescriptions, resulting in more time spent on caring for the patient directly.
In terms of communication and response time, PDAs also have the advantage over pagers, according to a study performed on a team of surgeons at St. Mary's Hospital in Paddington, England [source: BMC Medical Informatics and Decision Making]. Whereas using a pager requires a doctor to receive a page, locate a free phone and call back the number displayed on the pager, newer PDAs and smartphones allow doctors to communicate directly.
For lots more information about communications technology and how it affects our daily lives, see the next page.
How PDAs Work
Are PDAs a help or hindrance?
How Becoming a Doctor Works
How the iPhone Works
How a BlackBerry Works
How Smartphones Work
How Bluetooth Works
How Cell Phones Work
How Computer Memory Works
How Laptops Work
Aziz, Omer et al. "Handheld computers and the 21st century surgical team: a pilot study." BMC Medical Informatics and Decision Making. Aug. 18, 2005. http://www.biomedcentral.com/content/pdf/1472-6947-5-28.pdf
Elward, Kurt and Scott Strayer. "Patientcare device for asthma: utility and acceptability in primary care settings." University of Virginia Department of Family Medicine. Dec. 31, 2004.http://www.healthsystem.virginia.edu/internet/news/Archives05/pdafullstudy.cfm
George, Lynn and Lynda Davidson. "PDA use in nursing education: prepared for today, poised for tomorrow." Online Journal of Nursing Information. Vol. 9, No. 2. June 2005. http://eaa-knowledge.com/ojni/ni/9_2/george.htm
Kairer, Ryan. "More than 50% of U.S. doctors use handhelds." Palm Infocenter. Dec. 19, 2003. http://www.palminfocenter.com/view_story.asp?ID=6357
Krazit, Tom. "PDA sales hit a slump." PC World. April 27, 2004. http://www.pcworld.com/article/id,115879-page,1/article.html
Lemon, Sumner. "PDA sales increase sharply." PC World. May 4, 2005. http://www.pcworld.com/article/id,120698-page,1/article.html
Morrison, Jan. "UVA health system doctors first to use PDAs to diagnose and treat asthma." University of Virginia Health System. March 17, 2005. http://www.healthsystem.virginia.edu/internet/news/Archives05/pdaasthmastudy.cfm
Siracuse, Mark. "Doctor of pharmacy students' use of personal digital assistants." American Journal of Pharmaceutical Education. Feb. 15, 2008. http://findarticles.com/p/articles/mi_qa3833/is_200801/ai_n24394680/print
"PDAs beat pagers for doctor response times, says study." E-Health Insider. Aug. 23, 2005. http://www.e-health-insider.com/news/1386/pdas_beat_pagers_for_doctor_response_times,_says_study
5 Ways to Donate Your Old Smartphone or Cell Phone to Charity
We Need to Stop Believing These Five Tech Myths
You Don't Really Need Apps to Save Your Smartphone's Battery
6 Creative Uses for an Old Smartphone
Porting Out: It's Phone Fraud 101


text:
Longdom Journals Press Releases
Second-line Anti-Tuberculosis Drugs and Risk of Alopecia: A Retrospective Cohort study
Alopecia is not a well-known adverse effect of second-line anti-tuberculosis drugs. It is, however, been frequently reported in Eritrea and 83% of the reports of alopecia associated with second-line anti-TB drugs in the global adverse drug reaction database, as of July 25, 2017, were submitted from Eritrea. It is wondering why this much variation is happening and this study is therefore aimed at quantifying the risk, identifying possible risk factors and elucidating the causal association between alopecia and the second-line anti-TB drugs in Eritrea. This was an observational cohort study of PLWH on IPT enrolled from three Antiretroviral therapy (ART) Clinics in Eritrea. Causality and preventability of the cases were assessed using Naranjo probability scale and P-method respectively.
Find the full length article at: https://www.longdom.org/open-access/secondline-antituberculosis-drugs-and-risk-of-alopecia-a-retrospective-cohort-study-2167-1052-1000223.pdf
Alex Stewart
Gene Mutations
Journal of Genetic Syndromes & Gene Therapy
HBV Vaccine Used
Congenital Rubella with Autism
Medical Microbiology : A Guide to Microbial Infections
Agri and Aquaculture Biochemistry Bioinformatics & Systems Biology Business & Management Food & Nutrition General Science Genetics & Molecular Biology Medical Sciences Neuroscience & Psychology Nursing & Health Care
Copyright © 2020 Longdom Journals Press Releases. All rights reserved.


CIP Programme provides records of new and forthcoming books in advance of publication. It serves publishers as a bridge to the library book buying market.
The British Library contracts the administration of the CIP Programme and the creation of records to Bibliographic Data Services Limited (BDS) which is an independent, privately-owned company.
BDS gathers information from publishers on new and forthcoming books. Publishers can use a pre-printed forms to send in book information or can submit the title information form online.
Typical CIP record details include author, title and publisher, projected date of publication, pagination, ISBN and price.
BDS offers its services free to publishers.
Publishers in the United Kingdom have a legal obligation to send one copy of each of their publications to the Legal Deposit Office of the British Library within one month of publication.


text:
Q: IntegrityError at /new_food/(?P6\d+)/ : NOT NULL constraint failed: food_entry.refer_id views.py :
def new_entry(request, food_id):
    food=Food.objects.get(id=food_id)

    if request.method != 'POST':
        form=EntryForm()
    else:
        form=EntryForm(data=request.POST)
        if form.is_valid():
            new_entry=form.save(commit=False)
            new_entry.food=food
            new_entry.save()
            return HttpResponseRedirect(reverse('food',args=[food_id]))
    context={'food':food,'form':form}
    return render(request,'new_entry.html',context)

forms.py :
from django import forms
from .models import Food , Entry

class FoodForm(forms.ModelForm):
    class Meta:
        model= Food
        fields= ['name']
        labels= {'text':''}

class EntryForm(forms.ModelForm):
    class Meta:
        model=Entry
        fields=['item']
        labels={'text':''}

models.py
from django.db import models

# Create your models here.
class Food(models.Model):
   name=models.CharField(max_length=200)
   type=models.CharField(max_length=200)
   date_added=models.DateTimeField(auto_now_add=True)

   def __str__(self):
       return self.name

class Entry(models.Model):
    refer=models.ForeignKey(Food,on_delete=models.CASCADE)
    item=models.CharField(max_length=200)
    date_added=models.DateTimeField(auto_now_add=True)

    class Meta:
        verbose_name_plural='entries'

    def __str__(self):
        return self.item[:50]

Even after going through a lot of similar posts , I'm not being able to figure to out where is it going wrong , may be something is wrong in views.py but even after spending hours I'm not able to figure it out. Any help would be much appreciated .

A: Your foreign key is called refer but you're assigning food.
Either change the Entry to
class Entry(models.Model):
    food = models.ForeignKey(Food, on_delete=models.CASCADE)
    # ...

or the form code to
# ...
new_entry = form.save(commit=False)
new_entry.refer = food
new_entry.save()
# ...

My recommendation is the former, since food is a much better name for a foreign key referring to a food.


text:
Subscribe to our News Updates & Alerts
ASX AGN: A$
Clinical Advisory Committee
Announcements & Reports
About Argenica Therapeutics
Commercialising the novel neuroprotective therapeutic ARG-007 to reduce the damaging effects of stroke and other acute CNS injuries
Argenica Therapeutics was incorporated on 20 November 2019 as a proprietary Australian company to undertake the development and commercialisation of a novel drug based on the pioneering work of Professor Bruno Meloni and Clinical Professor Neville Knuckey at the University of Western Australia (UWA) and the Perron Institute for Neurological and Translational Science (Perron Institute). The drug, known as ARG-007, a cationic, arginine rich peptide, has neuroprotective properties that has the potential to offer protection to the brain following stroke and other acute central nervous system injuries. In June 2021, the Company listed on the ASX, raising the necessary funds to allow Argenica to develop a best in class neuroprotective therapeutic.
Drug development is tightly regulated and involves the sequential demonstration of both safety and efficacy of compounds. Argenica is undertaking the required Drug Research and Development Process to progress through to commercialisation. The Company is currently completing the pre-clinical safety and toxicity assessments required for entering clinical trials, with the Phase 1 clinical trial currently scheduled for initiation in the second half of 2021.
There is currently a large unmet need for a safe, early intervention therapeutic that provides protection to brain cells immediately following a stroke, until the underlying cause of stroke can be diagnosed and alleviated.
It is our mission to provide a solution for this unmet need. Our aim is for ARG-007 to be administered by first responders in the field to provide neuroprotective treatment prior to a patient's arrival at the hospital which will result in improved patient outcomes.
Mr Geoff Pocock (B.Sc., LLB)
Non- Executive Chairman
Mr Geoff Pocock is an experienced strategy consultant and commercialisation professional, with over 20 years' experience across the commercialisation process. Mr Pocock's experience has covered technical roles, executive management as well as significant corporate finance and strategy roles with a number of technology commercialisation ventures. Mr Pocock is the Principal of Polaris Consulting, a specialist boutique commercialisation strategy and executive services advisory business based in Western Australia, which also provides administrative services to businesses. He is also currently an Executive Director of Osteopore Ltd (ASX:OSX) and Non-Executive Director of EMVision Medical Devices Ltd (ASX:EMV) and former Managing Director/Co-Founder of Hazer Group (ASX: HZR)
Ms Liddy McCall (LLB, B. Juris, B.Com (Hons), GAID)
Ms Liddy McCall co-founded early stage venture fund, Yuuwa Capital LP and has over 20 years' experience as a founder, investor and in management of early stage startups. Her prior experience includes co-founder of iCeutica Inc group, Dimerix Limited (ASX:DXB) and Argus Biomedical Pty Ltd.Previously, Ms McCall was an Associate Director, Macquarie Bank focusing on mergers and acquisitions. Ms McCall has been admitted as a barrister and solicitor in various Australian jurisdictions. Ms McCall is on the Board of various companies including ASX listed AdAlta Limited (ASX:1AD), and unlisted companies, The Tailor Made Spirits Company Limited and SuperTrans Medical Limited.
Mr Terry Budge (B. Ecs, FAICD)
Mr Terry Budge was a Director of Aspen Group Limited from 6 May 2005 to 23 November 2012. He was also Chancellor of Murdoch University from 2006 to 2013 (appointed to Senate 1 June 2004). Mr Budgeholds a Bachelor of Economics from Monash University and is a Graduate of the Advanced ManagementProgram from Harvard Business School. He is also a Graduate and Fellow of the Australian Institute of Company Directors and a Senior Fellow of FINSIA. He is currently a non-executive director and Chairman of the Audit Committee of Westoz Investment Company Ltd (ASX:WIC).
Dr Liz Dallimore (B. Sc. (Hons), MBA, PhD)
Dr Liz Dallimore is a research & development, innovation and commercialisation specialist with over 20 years' experience across Australia and the UK. Prior to joining Argenica Therapeutics, Dr Dallimore was the Director of the WA Data Science Innovation Hub, tasked with working across WA businesses to establish innovative data science projects. Dr Dallimore has also held senior roles in management consulting across Australia, most recently as KPMG's National Director of Research Engagement and Commercialisation. Prior to this she held senior roles with Ernst & Young and PricewaterhouseCoopers. Dr Dallimore is a co-founder of medical device company Inspiring Holdings, sits on the AusBiotech WA Committee and is a non-executive Director of NERA, a Federal Government Growth Centre. Dr Dallimore has a PhD in Neuroscience jointly completed at Oxford University and the University of Western Australia and has worked as a neuroscientist at the Australian Neuromuscular Research Institute (now Perron Institute). In 2020, Dr Dallimore was recognised as one of Western Australia's Top Women in Tech.
Dr Samantha South (PhD, MBA, GAICD)
Chief Operating Officer / Executive Director
Dr Samantha South has over 13 years' experience in technology transfer and commercialisation within the medtech / biotech sector,as Senior Commercialisation Officer (Life Sciences) in the Research Development & Innovation Office at UWA and at the University of Queensland (UQ), and Queensland University of Technology (QUTBluebox). Dr South has extensive background in CNS research at Weill Medical College at Cornell University (NY), UQ and The Garvan Institute. She was also the Preclinical Manager at TetraQ, a preclinical contract organisation, specialising in central nervous system animal models.
Dr South was the UWA Director on UWA spin-out companies, MiReven Pty Ltd, Eridan Technologies Pty Ltd and OncoRes Medical Pty Ltd and is currently a Director of Rage Biotech Pty Ltd. Dr South is also the WA Ausbiotech Committee Chair and member of the Ausmedtech National Advisory Group and SBE LifeSciences Council.
Prof. Bruno Meloni
Prof. Meloni is the head of stroke laboratory research at UWA and the Perron Institute.
Prof. Meloni has over 25 years' experience as a research scientist, the last 20 in the field of stroke/cerebral ischaemia. His research in the stroke/cerebral ischaemia field has focussed on understanding the mechanisms associated with ischaemic brain injury, the identification of potential neuroprotective targets and the development of new therapies. Prof. Meloni has experience with designing preclinical stroke trials, and the use of peptides as neuroprotective agents.
Ms Emma Waldon
Chief Financial Officer / Company Secretary
Ms Waldon has diverse accounting, capital markets and corporate governance experience in Australia and the UK and is currently Company Secretary of EMVision Medical Devices Ltd (ASX:EMV) and a number of unlisted companies. Ms Waldon was Company Secretary of Hazer Group Limited (ASX: HZR). Ms Waldon was a director of Moko Social Media Ltd (ASX:MKB) when voluntary administrators were appointed to the company on 31 May 2017.
Dr David Blacker
Chairman of Clinical Advisory Committee
Professor David Blacker is an acute stroke clinician/neurologist who has previous experience initiating neuroprotection clinical stroke trials in Western Australia and being the local Principal Investigator of a number of national and international acute and secondary prevention stroke studies. Prof. Blacker is thePerron Institute Medical Director and consultant neurologist and stroke physician.
Prof. Geoffrey Donnan
Member of Clinical Advisory Committee
Professor Geoffrey Donnan AO is a Professor of Neurology at The University of Melbourne and former Director of The Florey Institute of Neuroscience and Mental Health. His research interest is clinical stroke management. He was co-founder, with Prof. Stephen Davis, of the Australian Stroke Trials Network (ASTN) within which there have been numerous investigator driven and other stroke trials. The first of these was the Australian Streptokinase Trial (ASK). He has since been involved in numerous clinical trials of therapy as Chair, Co-chair or Steering Committee member. These include ECASSII and more recently EPITHET. He is currently Co-chair of the EXTEND group of trials, including the recently published EXTEND IAtrial of thrombectomy in acute ischaemic stroke. The EXTEND trial itself, in which thrombolysis was safely and effectively given out to 9 hours, was also recently published, again with Prof. Davis. He was a co-founder of Neurosciences Trials Australia and has a major interest in the imaging of the ischaemic penumbra. The interface between basic sciences and clinical stroke medicine has been a research focus and, in collaboration with Messrs Malcolm Macleod and David Howells, has adapted the meta-analysis technique to assess therapies in animal stroke models. He was Editor-in-Chief of the International Journal of Stroke and is Past President of the World Stroke Organization. In 2012 he was appointed an Officer of the Order of Australia for his distinguished service to neurology and research contributions and is the recipient of a number of international awards including the American Stroke Association William Feinberg Award (2007), the World Stroke Organization Leadership Award (2012), Karolinska Institute Award (2012) and Wepfer Award Of the European Stroke Congress for excellence in stroke research (2014).
Associate Prof. Paul Bailey
Assoc. Prof. Paul Bailey is Medical Director for St John Ambulance Western Australia. Assoc. Prof. Bailey is Perth based, completing his medical degree at the University of Western Australia in 1992, and becoming a Fellow of the Australasian College for Emergency Medicine in 2000. He completed a Biochemistry / Physiology laboratory PhD in 2007 – investigating the functional and structural characteristics of Australian jellyfish venom. More recently Assoc. Assoc. Prof. Bailey's research focus has been in the areas of out of hospital cardiac arrest, anaphylaxis, emergency department systems and trauma – with 29 papers published in the scientific literature since 2015. In early 2020, Assoc. Prof. Bailey successfully completed the AICD's Company Directors course. Assoc. Prof. Bailey and his team are active participants in the WA Stroke Advisory Group – which has transformed the clinical approach to stroke patients in the prehospital environment in WA.
Dr Tim Phillips
Dr Tim Phillips is an Interventional Neuroradiologist with 15 years' experience, currently working at the Neurological Intervention and Imaging Service of Western Australia (NIIS WA) and the Perth Children's Hospital. Prior to returning to Perth he undertook post-specialist fellowship training at the Royal Melbourne Hospital, The Royal London Hospital, Queens Hospital Romford, The National Hospital for Neurology and Neurosurgery, and Great Ormond Street Hospital.
Argenica is undertaking the development and commercialisation of ARG-007 developed by world-leading researchers at UWA and the Perron Institute.
Development of the underlying technology has progressed over the last 6 years from initial concept and proof-of-concept experiments through pre-clinical research. Argenica is now poised to begin the human testing phase of product development for its initial target application of acute ischaemic stroke. Our ongoing partnerships with UWA and the Perron Institute will provide continuing research and pipeline development.
Subscribe to our mailing list to stay up to date with Argenica Therapeutics
Argenica Therapeutics Limited
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Nedlands WA 6009, Australia
PO Box 1458, West Perth WA 6872
info@argenica.com.au
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I Create With Many Different Mediums.
My personal work tends toward dreamy abstraction or magical realism.
Im fascinated with water and reflections, and all the stories they can tell.
I often paint reflections of past civilizations or events.
Travel inspires me, though I never just copy my photographs.
because they found it interesting enough to live with.
environment to tell their own stories.


ලංකාවේ ධනවත් ම දේශපාලකයන් 10දෙනා පිළිබඳ තොරතුරු ඇත්ත ද?
ෆෝබ්ස් සඟරාව උපුටා දක්වමින් ඒෂියන් ට්‍රිබියුන් වෙබ් අඩවිය හා තවත් මාධ්‍ය රැසක වාර්තා කර තිබෙන ආකාරයට ලංකාවේ ධනවත් ම දේශපාලකයන් හා ඔවුන් සතු ධනයේ වටිනාකම මෙසේයි.
මෙම වාර්තාවේ සත්‍යාසත්‍යතාව සොයා බලා අප කළ අධ්‍යයනයේදී අපට ෆෝබ්ස් සඟරාවේ මූලාශ්‍ර‍යක් සොයා ගත නො හැකි වුණා.
එසේම, මේ පිළිබඳ ඒෂියන් ට්‍රිබියුන්ට අමතරව වාර්තා කර තිබුණු වෙබ් අඩවි දෙකක් වන මෙන්න මේ වෙබ් අඩවි දෙක බලන්න. එ් දෙක පුදුම සහගත අන්දමින් එක හා සමානයි. මේ ගවේශනයට ඔබත් එක් වන්න.
ඔබ ලක්ෂ හතරකට වඩා ණයගැතියකු බවට පත් කළේ කවුරු ද?
ශ්‍රී ලංකා නිදහස් පක්ෂය තව දුරටත් ආණ්ඩුවේ ඉන්නේ කුමට ද?
These figures (from #4 down) are laughable to say the least.
I am sure there are thousands of people in SL with assets over 2 million dollars.
ධනවත්ම පුද්ගලයින් ද, දේශපාලකයින් ද?
දැන් ඔබතුමා කියන්නේ මේ ගවේශනයට ඔබත් එක් වන්න කියලා …. ඔබතුමා මේ වගේ දේවල් මේ තරම් සීරියස් ගන්නවද ?
හරි එතකොට කවදාද ෆෝබ්ස් සගරාව Top 10 Most Beautiful Hot Sri Lankan Actresses ලව තේරුවේ…..
මෙහෙම යන කොට මේ සයිට් එක පටන් අරන් තියෙන්නේ ගොසිප් සයිට් එකක් කරන්න වගේ …..
ඉස්සෙල්ලා මෙලෝ රහක් නැති එක එක ශරීර අංග නිසා ජනප්‍රිය වෙච්ච ඉන්දීය ශ්‍රී දේවී දැන් මේක ….
මේක එහෙම දාන්න එපා …… Top 10 Most Beautiful Hot Sri Lankan Actresses ….ඊළගට ….
පැරා නිකන් දැන් පලාත්පාලන චන්දෙන් පස්සේ මැතිවරණ කොමසරිගේ ගානට වැටිලා!
Dear Para, I really love your writings. but please do not loose your reputation on this type of mud slings.
I have clearly said this in the report.
//මෙම වාර්තාවේ සත්‍යාසත්‍යතාව සොයා බලා අප කළ අධ්‍යයනයේදී අපට ෆෝබ්ස් සඟරාවේ මූලාශ්‍ර‍යක් සොයා ගත නො හැකි වුණා.
I am more interested in studying how these reports come. Why do websites like Asian Tribune publish such stories? Who pays for them? Why? Do you have any clue?
Really know clue. But 18 Billion dollar means 3 times of our foreign reserve. It's too much. See for Ranil its about 1 Mill USD around 160 Mil LKR. His Land in Cambridge Terrace should cost more than that. That's why I'm calling it Mud sling.
By the way websites trying to increase there web traffic. If someone paying, they are paying to up MRs "reputation" as a corrupted politician.


Being a medical student is tough stuff. Thankfully, there are multiple organizations and resources that you can use to help make things a bit easier. To celebrate World Mental Health Day 2019, the NSWMSC is also proud to announce its NSWSMC Mental Health Contacts for Medical Students Poster.
This is poster is a 'one-stop-shop' for mental health services that provide FREE SUPPORT for medical students. There are a TONNE of resources and services out there to support the mental health of medical students, but navigating through them all and knowing which service to access for help with each particular issue can be overwhelming and confusing.
Because of this, the NSWMSC put them all together in one hand poster. The poster is full of FREE mental health service that medical students can use for almost ANY mental health concern that you may come across. Everything 'mental health support' that you could ever want is on the poster!
Every medical school in NSW and the ACT have GIANT A2 versions of this poster put up around. their medical school. Be sure to track down where yours has been placed! All of these services are to support you, free of charge.


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With this amazing platform you'll find relevant and engaging content to include videos and news all of which can be posted with a simple click of the mouse.
It also creates incredible image posts without any photo editing experience.
You can also measure your social media performance, which helps you get more traffic and generate new leads.
It's amazing and it's free so signup below and give it a try.
A social media management company is something you should look into if you have a business or are well known online. This kind of service will allow you to hire someone to keep up with your social media accounts. That way, you can work and live your life and if something important happens you'll be on top of it.
The first benefit you can expect to have with a social media management company helping you is that you are going to be able to deal with complaints about your company. Let's say that you get a message that says someone is not happy with your product or service. It's important that you deal with these kinds of things quickly. Otherwise, the person could get fed up and may start shopping elsewhere. Word spreads fast if customers are not happy due to the Internet, so you have to be careful not to ignore customers.
Social media is a type of website that never shuts off. People are going to be on these sites at all times, day and night. That means you're going to want to have someone that can deal with your social media profile pages on a regular basis just to keep up with people. If you have a lot of people commenting because you're really popular, you have to have someone fielding the questions and letting you know when something important is being discussed so you can respond to it.
You need to know how to build your profile properly so that it can reach out to the most people possible. One thing you need to remember is that everyone is different, so you don't want your profile to have something on it that people don't agree with if you're representing a company. For instance, if you say that you're someone that only believes in a certain religion, you may end up alienating yourself to only those that agree with you. A management company can make your page something that everyone can agree is good due to the fact that it's only about business or keeping fans in the know about what you're doing.
Reputation management is something that a company like this can help you with. When someone, for instance, leaves a bad review about you on your social media profile, you have to know about it so you can respond accordingly. People will be able to see what you say, so make sure you don't lose your cool. It's best to let the management company handle it, and if you tell that person you'll give their money back or make it right somehow, you're going to want to follow through.
Being careful about what you share is important because people are going to assume this is your company speaking and not you personally. Let's say you're interested in sports and are tempted to gloat about your team's victory that day. Your management company will probably tell you this is not a good idea because some of your customers may not be fans as well. You have to take a neutral approach to what you share and assume that other people are potential customers. Having the ability to have someone else deal with your profile professionally will let you live your personal life and professional one separately.
You shouldn't just get help with your business profile, you should also ask the company to work on your personal page. People are going to look into what you're doing if you have your name attached to your business. Even if you're someone that's famous on a website like one where you share videos, you don't want people to find your personal profile and see things like you drinking on it. It's good to remember that everything you put online is able to be seen by everyone eventually no matter how private settings are because the site could be hacked or someone could take a screenshot of your comments.
Social media websites are going to change over time, and people are going to migrate to different ones. You're going to want to work with those who can stay on top of what is going on and what is popular. For instance, if one site starts to lose popularity in favor of another, you're going to want to have the company set up a profile for you wherever people are going. When one site quits being cool, people tend to switch it up and a good management company will help you stay on top of that.
Anyone that has an online presence or a business should work with a social media management company. That way, you can always be sure to have someone there to keep track of your profiles. Otherwise, you may lose customers because they won't have anything new to look at and may unfollow you.
A thing to notice about the Social Media Marketing services is that they're affordable. You don't need to spend a whole lot of cash, but they do provide a set of results. They bring you value and quality, all while keeping the costs low.
Social Media Marketing's benefit is that it makes it possible to get more exposure. The thing is that the vulnerability is extremely large with so many people using Social Media. You will be pleased with the value and the outcome which you can obtain here!
People want to feel that you send them a set of results. They wish to feel social and valued Social Media Marketing lets them feel like that. It's definitely among the best investments that you can make for your company.
Finding market insights that are great costs a whole lot of money, with companies. With some social media marketing services, you don't have to worry about that. That is the results you get here are likely to impress in the long run and what makes this sort of service useful.
In the last few decades, social media marketing has begun to acquire an extremely significant role in the internet world. With approximately two billion people there is no denying that companies are currently trying to make and pursue a following on networking. That is social media marketing is something that you need to concentrate on as you can and what makes a difference.
It's really tough to do so, but you should not worry that much as a following can be gotten via a set of services and media marketing.
If you would like to sell things and create the following traffic is vital. Encourage them to see your website and you should try to talk to your clients. A lot of them will do this if you would like to obtain outcomes in the long haul and the experience, and you need followers.
You should think about investing in social media marketing as soon as possible. This should be a priority as it helps deliver the result and an experience such as this with your company can be very worth it. Provided that you're currently working hard to promote your business and you need to acquire an excellent experience social media marketing is the ideal fit for you!
With almost every kind of business and business procedures now on the web in this era of state-of-the-art technology, even if you do not specifically wish to be an integral part of social media, you will not triumph if you don't. Simply because your competitions plus your existing and prospective customers are on the web and you need to keep abreast of occurrences. Hence, you will need social media monitoring resources.
The appearing of the social media has an excellent potential for businesses to obtain a major look into relevant niches. Despite complicated economic stages, an economical level of research is suitably provided by way of social media. The only thing that is necessary for you to do is implement social media stats and boost its use.
Ahead of the introduction of social media, what market professionals do on a normal schedule is come to a decision between wanting current market forecasts and the restrictions of their finances and resources. Most of options for research were expensive. These comprise forms and surveys, focus groups, media scanning, contact-tapping and a variety of other techniques.
These commonly used a whole lot of men and women, cash and time.
Social media monitoring instruments are trendy right now since companies are employing social media to accomplish their brand new and broad research. On top of that, the business opportunities for social media research are completely unique. As an example, B2B and B2C conversations with each other can now be documented, stored, searchable on automation and most important, available to the populace.
While it's an undeniable fact that conventional research techniques still has some quality, utilizing social media statistics coupled with monitoring social media can cheaply substitute a few of them. Those that can't be replaced can be compounded by social media and assist in making a final result set that's better and extensive.
Social media monitoring tools guide experts in the field of marketing and advertising to change face-to-face focus teams. This is done by the identification of buyer discussions, browsing the comments of the focus group and delivering professionals with the information so that social media analytics can be performed.
The advantages in terms of value are perfect. As an alternative to market researchers being brought to a number of towns, countries, states and urban centers , the corporation can simply tap into online conversations that happen to be effectively built globally local.


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Enlight bolsters Central and Eastern European solar position with Croatia asset acquisition
By Liam Stoker
Power Plants, Financial & Legal, Markets & Finance, Projects
Enlight's Atilla solar PV project in Hungary. Image: Enlight.
Enlight Renewable Energy is to acquire and co-develop almost 400MW of solar PV in Croatia, bolstering its position in Europe's solar market.
The Israel-headquartered independent power producer (IPP) has agreed to acquire a 525MW portfolio of solar and wind projects in the country which are at various stages of development.
The portfolio comprises four solar projects with a combined generating capacity of 386MW and one wind project with a total capacity of 139MW.
Construction of the portfolio is expected to commence between the end of 2023 and 2025, Enlight said.
While Enlight already has an operational onshore wind farm in Croatia – the 48.75MW Lukovac project in Split-Dalmatia – the deal marks the IPP's maiden investment in Croatian solar and strengthens its presence in Central and Eastern European (CEE) solar markets.
Enlight's CEE renewables portfolio currently includes projects in Hungary, Kosovo and Serbia, as well as Croatia. Its portfolio stands at 1.2GW, of which 316MW is operational.
Enlight has historically looked to bolster its portfolio through M&A activity, last year acquiring a 90% stake in US solar and storage developer Clēnera in June 2021 before picking up a 490MWdc array of Spanish solar projects from Cerberus Capital Management later that year.
central europe, croatia, eastern europe, enlight, european solar, lss cee, solar energy


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Robin Beth Schaer
Full-Time Lecturer in Creative Writing
rbs116@case.edu
Robin Beth Schaer is a poet and essayist whose research and teaching interests include hybrid forms, contemporary poetry, environmental writing, documentary poetics, gender & sexuality studies, global literature, and Jewish studies. She is the author of the poetry collection Shipbreaking (Anhinga 2015) and a work in progress on art and atrocity. Her recent awards include the Creative Capital Award Shortlist in 2022, a Creative Writing Fellowship from The National Endowment for the Arts in 2021, and an Ohio Arts Council Individual Excellence Award in 2020. She has received fellowships from Yaddo, MacDowell Colony, Djerassi Resident Artists Program, Saltonstall Foundation, Vermont Studio Center, and Virginia Center for the Creative Arts. Her work has appeared in Tin House, Paris Review, and Guernica, among others. Schaer was educated at Colgate University and Columbia University's School of the Arts. She has taught writing in New York, New Jersey, and Ohio, and she worked as a deckhand aboard the Tall Ship Bounty, a 180-foot ship lost in Hurricane Sandy.


The Badger basketball team stopped Northwestern cold in the second half, leading the game early in the half by 9 the Badgers went on a 23-7 run that saw Northwestern go scoreless for 3 minutes. With the Badgers second half run they went on to win the game by a score of 74-45, but do not let the final score fool you there was value in this victory. Against Northwestern Jason Bohannon showed further signs he is breaking out of his early season shooting funk, scoring a career high 20 points on 8 of 12 shooting from the field. Also Jon Leuer continued to show an agressiveness on the offensive end that is making him a very dangerous scorer, he finished with 15 on 6 of 9 shooting. In an odd bit of coaching, despite the Badgers up almost 30 with ten minutes to go Bo Ryan did not get the reserves much playing time. Freshman Rob Wilson only played 4 minutes, however hit a three pointer, after great ball movement set him up. Fellow freshman Jordan Talyor played 6 minutes and scored 2 points, he also missed a free throw which is becoming an all to common theme.