text:
Springfield seeks demolition bids ahead of delayed $3 million Central Street corridor improvement project
The city is preparing to demolish buildings on Central, Walnut and Hickory streets as part of the Central Street corridor improvement project. Buildings and related land takings are shown in city rendering from 2016, prior to approval
SPRINGFIELD — The city is seeking bids for the demolition of two vacant buildings along the Central Street corridor, a key milestone as the city prepares to begin a long-awaited, $3 million corridor improvement project.
Christopher Cignoli, the city's director of public works, said Thursday that once the demolition work begins, the city will be ready to advertise for bids for the road reconstruction project. The road project in the Maple High-Six Corners area should be ready to begin Oct. 1, he said.
Cignoli said it is nice to be near the point of construction in what seems like a project that has taken "forever."
"Finally, this is really the first step of the project," Cignoli said.
The final property takings were approved in February by the City Council after years of planning, design and neighborhood discussions.
Springfield City Council approves final property takings for $3 million Central Street corridor improvement project
The Springfield City Council approved two property takings on Monday at a cost of $265,000 needed for the $3 million Central Street corridor improvement project in Maple High-Six Corners area.
Bids for demolition, removal and site work are due Aug. 15, for the two buildings which were taken by the city by eminent domain. The buildings slated for demolition are 462 Central St. which formally housed Kevin's Towing and two other automotive businesses; and 468 Walnut St., which formerly housed Impocco's Poultry Market.
The cost of demolishing and cleaning up both properties is estimated to total $197,000. Bids must be submitted at the Office of Procurement at City Hall by the 2 p.m. deadline.
The corridor project will result in realignment and reconstruction of roadways, reconstruction of sidewalks, traffic signalization, landscape improvements, new pedestrian crosswalks, a widening of one narrow section of Hickory Street, and a new entrance area to Ruth Elizabeth Park, Cignoli said.
There are also plans to demolish a two-family house at 46-48 Hickory St., also taken by eminent domain tied to the corridor and park projects, said Tina Quagliator-Sullivan, the city's deputy director of disaster recovery. The city is in the process of helping the tenants relocate under eminent domain guidelines, and will then demolish the site in a separate bid process, she said.
The road reconstruction project is centered along Central Street from Pine Street to Hancock Street and on Hickory Street from Hancock to Eastern Avenue. The project and property takings are being financed by grant funds from the federal Community Development Block Grant Disaster Recovery Program.
In a related action, the city began advertising for bids this week for a renovation project at Ruth Elizabeth Park, in the corridor area.
Bids are due Aug. 22, and the project will include new paved pathways, regrading, sediment and erosion controls, signage, a new pavilion and site furnishings and landscaping. The project has an estimated cost of $200,000.
The Central Street corridor project has been discussed for many years, and construction was hoped to begin in 2018, and then in the spring or summer of 2019.
A key reason for the delay was a very prolonged process to get federal approval for redesigning the park entrance, Cignoli said. The city needed to transfer some parkland for the road widening project, and had to replace it with other land and redesign the entrance.
The property takings for the corridor project had triggered some concerns in recent years but were approved by the City Council in 2018 and 2019.
The property taking at 462 Central St., was for $225,000, and the city taking of the property at 468 Walnut St., was for $140,000. The taking of 45-48 Hickory St., was approved for $125,000.
The city is required by law to pay fair market value for properties taken by eminent domain and must also pay for relocation costs, officials said.


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Qualifications & Guidelines
We Empower Women
Watch Our Story
Brittany Ayala Sasha Graham Hayoun Lim Jennifer Ochoa
Brittany Ayala
Brittany, a political science major, has shown a curiosity for history throughout her life. Even though she has faced daunting challenges, she has shown courage and determination to rise above circumstances that might have deterred others. As Brittany finishes up her community college education (Diablo Valley College) and heads off to a four-year university, she chooses to major in political science and will be well on her way to reaching her goal of becoming a civil rights attorney.
Sasha's determination and "can-do" attitude exude! Against all odds she has put herself through community college, excelling in her classes. Her experiences with extreme poverty inform her perspectives on how to assist others facing similar realities. Sasha will be pursuing ethnic studies and pre-law classes at a four-year university. Her goal is to return to her community as a support for others.
Hayoun Lim
AP scholar Hayoun Lim is a College Park High School Student who is interested in the field of mechanical engineering. Her love of robotic design and creation is obvious. While in high school she has participated in robotics competitions and in events that help introduce and explain robotics to others. Recently she participated in a "Girls Who Code" summer immersion program.
Jennifer Ochoa
Jennifer currently volunteers as a peer mentor at Diablo Valley College and wants to continue mentoring and guiding students as a career following her college graduation. She will be pursuing a degree in psychology and will be the first in her family to graduate from college. Jennifer plans to attend either UC Santa Cruz or Berkeley and following graduation Jennifer intends to pursue a Masters' Degree in Counseling.
© 2019 by Blackhawk Women's Scholarship Fund PO Box 2991, Danville, CA 94526
copyright 2016 by NN

redpajama_set_name: RedPajamaCommonCrawl


You should never pay full price while on vacation if you can help it. That's why Best Western is partnered with us to offer you discount coupons that will substantially reduce your costs on vacation. Best Western Discount Coupons will reduce your stay cost, allowing you to enjoy your vacation for longer. As the premier mid-scale hotel franchise in the world, Best Western is able to provide a great quality product to you for less than many competitors while providing a warm and consistent level of customer service. Each property has a set of standard amenities, a well trained staff, and bonus plans for select guests such as the Biker and Airline Partner bonuses. You can save more money by taking advantage of on-property amenities such as pools, restaurants, and saunas. Your Best Western Hotel should have everything you could need during your stay and they are happy to accommodate you.
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text:
<?php

namespace pukoframework\middleware;

use pukoframework\peh\ThrowConsole;
use Ratchet\MessageComponentInterface;

/**
 * Class Sockets
 * @package pukoframework\middleware
 */
abstract class Sockets extends Controller implements MessageComponentInterface
{

    var $SOCKET_PORT = 8090;

    /**
     * Console constructor.
     */
    public function __construct()
    {
        $exception_handler = new ThrowConsole('Sockets Error');
        $exception_handler->setLogger($this);

        set_exception_handler(array($exception_handler, 'ExceptionHandler'));
        set_error_handler(array($exception_handler, 'ErrorHandler'));
    }

    public function BeforeInitialize()
    {
        return array();
    }

    public function AfterInitialize()
    {
        return array();
    }
}

redpajama_set_name: RedPajamaGithub


text:
58David Schweikert
27Carolyn Maloney
26Scott Garrett
25Barney Frank
24Sheila Jackson Lee
22Maxine Waters
21Spencer Bachus
20Ted Poe
20Judy Biggert
20Bob Dold
David Schweikert
Showing 1 - 20 of 58 Show 58
December 12, 2012 Last Aired January 8, 2013
Financial Industry Regulations
Witnesses testified on the implementation of Title VII of the Dodd-Frank financial regulations law, which deals with over-the-counter derivatives and swaps market regulations. Commodity…
December 5, 2012 Last Aired December 5, 2012
House Session, Part 2
The U.S. House of Representatives convened for a legislative session.
View in Congressional Chronicle139 views
September 20, 2012 Last Aired November 16, 2012
Consumer Financial Protection Bureau Report
Richard Cordray gave his semi-annual report to Congress of the Consumer Financial Protection Bureau (CFPB). In his testimony he said that the CFPB would draft a proposal to address a provision of…
September 21, 2012 Last Aired September 21, 2012
House Session
July 25, 2012 Last Aired August 21, 2012
Financial Stability Oversight Council Report
Treasury Secretary Geithner testified on the annual report of the Financial Stability Oversight Council (FSOC), created by the Dodd-Frank financial regulations law to monitor excessive risk taking and…
July 25, 2012 Last Aired July 25, 2012
The House debated resolutions relating to offshore drilling.
JPMorgan Chase Trading Loss, Jamie Dimon Testimony
Jamie Dimon testified on JPMorgan Chase's $2 billion trading loss on May 10, 2012 He apologized for the trading losses, but he stressed that no taxpayer money was lost and that the bank…
View in Congressional Chronicle84 views
June 1, 2012 Last Aired June 8, 2012
Cyberthreats to the U.S. Financial Industry
Witnesses testified on cybersecurity threats to the U.S. financial industry. The focused on the scope of the problem and specific threats to the financial sector. Other topics included the…
May 8, 2012 Last Aired May 13, 2012
Federal Reserve Reform, Congressional Panel
Representatives Kevin Brady (R-TX) and Barney Frank (D-MA) testified on their differing legislative proposals to reform the Federal Reserve System. Representative Brady's version included getting…
Federal Reserve Reform, Economists Panel
Economists testified on legislative proposals that either reform abolish the Federal Reserve System.
May 9, 2012 Last Aired May 9, 2012
The House worked on commerce, justice and science appropriations.
View in Congressional Chronicle23,199 views
The House debated federal spending for the Commerce and Justice Departments and science agencies.
View in Congressional Chronicle1,711 views
On Wednesday, the House will meet at 10:00 a.m. for morning hour and 12:00 p.m. for legislative business. First votes expected: 1:30 - 2:30 p.m. Last votes expected: 4:00 - 5:00 p.m. One…
March 28, 2012 Last Aired March 28, 2012
H.R. 1339 - To amend title 32, the body of laws of the US dealing with the National Guard, to recognize the Salem, MA, as the Birthplace of the National Guard (Sponsored by Rep. Tierney…
1) Concur in the Senate Amendment to H.R. 3606 - Jumpstart Our Business Startups (JOBS) Act 2) Legislation Related to H.R. 4239 - Surface Transportation Extension Act of 2012 Begin…
House Republican Leadership on JOBS Act
House Republican leaders spoke to reporters after a vote on a bill that reduces regulations for businesses going public. The legislation passed 390-23.
One Minute Speeches (5 per side) Complete Consideration of H.R. 3606 - Jumpstart Our Business Startups (JOBS) Act (Structured Rule) (Sponsored by Rep. Stephen Fincher / Financial Services…


text:
info@t-stripe.com
Window heating system
Condensation water
Airing and heating
In 2010 the IBO conducted a study about T-STRIPE
The effectiveness of T-STRIPE in preventing condensation has already been proven by two independent entities; the Austrian Institute for Healthy and Ecological Building (IBO) and the certified expert and graduate engineer Günther Apfelbacher.
While studying the heat bridge effect with an outdoor temperature of minus twelve degrees (-12°) centigrade the following results could be observed: Without T-STRIPE the lowest measured temperatures on the inside surface of the window pane were seven (7°) degrees along the edges of the pane. With T-STRIPE the lowest recorded temperature on the glass surface was sixteen (16°) degrees in the middle of the window pane. During these tests the T-STRIPE heating element itself reached a temperature of 38.9 degrees.
Maximilan Hron (left), inventor and managing director of T-STRIPE und Felix Heisinger of the IBO, author of the study, at a press conference presenting the study's results.
Mr. Heisinger summed up the effectiveness of T-STRIPE: 'With T-STRIPE none of the limits for condensation or mold spores were close of being violated, and neither condensation water nor mold did occur.'
The study also unveiled another positive side effect of T-STRIPE. By heating up the window pane along the edges the resulting warm air circulation raises the temperature of the window as a whole. Most of this heat radiates back into the room, raising room temperature and therefore indoor environment quality as well. Up to 63.2% of invested thermal energy is being reflected back into the room.
Often times people who have problems with condensation on their windows are being advised to simply air their rooms more often and to turn up their radiators. Compared to these methods T-STRIPE offers several advantages.
By increasing the airflow within a room excessive humidity could be reduced and an increase in comfort can be achieved as well – as long as certain temperatures are not being exceeded – but condensation water can never be fully avoided. Additional heating expenses also depend on what heating system is being used. All of these methods do not reduce the likelyhood of condensation to occur.
Only with T-STRIPE condensation water becomes a thing of the past, the heat dissipation effect adds to a comfortable room climate.
Find the study here.
Certified expert and graduate engineer Günther Apfelbacher also confirmed the advantages and effectiveness of T-STRIPE:
"…it should be considered that – especially with regards to availability on the market – the T-STRIPE system marks an unprecedented contribution on the subject of condensation and mold spore prevention in conjunction with window constructions and exterior walls.
"Usage of the system in connection with a controlling unit for the purposes of minimizing energy costs (i.e. thermostat) can generelly be recommended."
"The T-STRIPE heating system is the first truly flexible heating system that combats condensation along the edges of window panes."
"One of the advantages of the system is the fact that it can be assembled and installed even in places where no other alternatives remain."
"In closing it should be remarked that assembly and installation of the system is entirely customizable and can therefore be practically invisible to the naked eye."
Over the years I spent finding a solution for my problems with condensation water, I met a lot of people who were equally frustrated. After coming up with invention I decided to introduce it onto the market.' says T-STRIPE inventor and engineer Maximilian Hron. 'Since I always wanted to provide my customers with a satisfaction guarantee, I made various experts conduct studies on T-STRIPE.
T-STRIPE - window heating system that stops window condensation --- +43 1 997 17 49 --- info@t-stripe.com --- www.t-stripe.com
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This historic building designed by JRA Architects in 1938, and the addition in 1963 are rich with Art Deco style elements. This 13 story high-rise office building with 10 story wing addition in downtown Frankfort, Kentucky, includes complete restoration and renovation of the exterior and interior.
The building interior includes 384,000 square feet of renovated area. The lower level cafeteria and kitchen will be replaced with new office suites and a new secured accessible entrance from the employee parking. The first floor will have it's historic finishes restored and existing office areas will become flexible training rooms for the Commonwealth along with a central security station for the building. A restored 214 seat auditorium at this level will feature new seating with tablet arms, power/data for lap top computers, an accessible stage and state-of-the-art audio and video conferencing capabilities. The remaining floors will be designed with open office flexibility with carpet tiles and monolithic acoustical ceilings for flexible tenant layout. A new central core has been efficiently redesigned retaining remnants of the "historic" lobby and connects three banks of renovated elevators, a freight elevator, new accessible toilet rooms, a central kitchenette and egress stairs. JRA worked closely with The Landmark Committee for review and approval of the restored or replaced building elements.
The exterior restoration involves masonry cleaning of brick and limestone, and full replacement of windows to their original 1938 design. An 8' high by 20' deep inaccessible plaza which surrounds three sides of the building will have new adjacent handicapped parking and becomes accessible to three monumental entrances creating a park like plaza. Five 18' square limestone clad pergolas are designed for corner points of the plaza. These open-air educational structures featuring changing exhibits, are connected by new walkways with new site lighting, outdoor furniture and landscaping to be utilized and enjoyed by the public and building employees.


F22 – New Academic Scene is a long-term project of the Academy for Dramatic Arts aiming to open up public space to up-and-coming theatrical artists and present their recent work to theatre audience. Inspired by extremely successful performances of several of our exam plays, which continued to live a stage life even beyond the regular classes at the Department of Sacting and Stage Directing and Radio, wishing to provide our students – future artists and theatre professionals – professional working conditions and creative environment. Be it graduation performances or Academy festivals, we have established a new scene open for different events in performative arts and offered free cultural events to the audience.


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A pseudo-prize for pseudo-research into pseudo-medicine
Published Friday 30 March 2018
An announcement (it's in German, I'm afraid) proudly declaring that 'homeopathy fulfils the criteria of evidence-based medicine' caught my attention.
Here is the story:
In 2016, Dr. Melanie Wölk, did a 'Master of Science'* at the 'Donau University' in Krems, Austria investigating the question whether homeopathy follows the rules of evidence-based medicine (EBM). She arrived at the conclusion that YES, IT DOES! This pleased the leading Austrian manufacturer of homeopathics (Dr Peithner) so much and so durably that, on 23 March 2018, he gave her a 'scientific' award (the annual Peithner award) for her 'research'.
Her paper is unpublished, or at least not available on Medline; therefore, I am unable to evaluate it directly. All I know about it from the announcement is that she did her 'research at the 'Zentrum für Traditionelle Chinesische Medizin und Komplementärmedizin' of the said university. A quick Medline search revealed that this unit has never published anything, not a single paper, it seems! Disappointed I search for Dr. Christine Schauhuber, the leader of the unit; and again I find no Medline-listed publications in her name. My interim conclusion is thus that this institution might not be at the cutting edge of science.
But what do we know about Dr. Melanie Wölk's award-winning master thesis *?
The announcement tells us that she investigated all RCTs published between 2010 and 2016. In addition, she evaluated:
the 'Swiss report',
the NHMRC report,
Shang 2005,
Ernst 2002,
the Frass sepsis trial of 2005,
Linde 1997 (why not Linde 1999? I ask myself; perhaps because this re-analysis of the same material came to a largly negative conclusion?)
On that basis, she arrived at her positive verdict – not just tentatively, but without doubt ("Das Ergebnis steht fest").
Dr Peithner, the owner of the company and awarder of the prize, was quoted stating that this is a very important piece of work for homeopathy; it shows yet again what we see in our daily routine, namely that homeopathics are effective. Wölk's investigation demonstrates furthermore that high-quality trials of homeopathy do exist, and that it is time to end the witch-hunt aimed at discrediting an effective therapy. Conventional medicine and homeopathy ought to finally work hand in hand – for the benefit of our patients. ("Für die Homöopathie ist das eine sehr wichtige Arbeit, die wieder zeigt, was wir in der ärztlichen Praxis täglich erleben, nämlich dass homöopathische Arzneimittel wirken. Wölks Untersuchung zeigt weiters deutlich, dass es sehr wohl hochqualitative Homöopathie-Studien gibt und es an der Zeit ist, die Hexenjagd zu beenden, mit der eine wirksame medizinische Therapie diskreditiert werden soll. Konventionelle Medizin und Homöopathie sollten endlich Hand in Hand arbeiten – zum Wohle der Patientinnen und Patienten.")
I do hope that Dr Wölk uses the prize money (by no means a fortune; see photo) to buy some time for publishing her work (one of my teachers, all those years ago, used to say 'unpublished research is no research') so that we can all benefit from it. Until it becomes available, I should perhaps mention that the description of her methodology (publications between 2010 and 2016 [plus a few other papers that nicely fitted the arguments?]; including one Linde review and not his more recent re-analysis [see above]) does not inspire me to think that Dr Wölk's research was anywhere near rigorous, systematic or complete. In the same vein, I am tempted to point out that the Swiss report is probably the very last document I would select, if I wanted to generate an objective picture about the value of homeopathy.
Taking all this into account, I conclude that we seem to be dealing here with a
pseudo-prize (given by a commercial firm to further its business) for a piece of
pseudo-research (the project seems to have been aimed to white-wash homeopathy) into
pseudo-medicine (a treatment that has been tested extensively but has not been shown to work beyond placebo).
*Wölk, Melanie: Eminenz oder Evidenz: Die Homöopathie auf dem Prüfstand der Evidence based Medicine. Masterarbeit zur Erlangung des akademischen Abschlusses Master of Science im Universitätslehrgang Natural Medicine. Donau-Universität Krems, Department für Gesundheitswissenschaften und Biomedizin. Krems, Mai 2016.
Posted in alternative medicine, bias, bogus claims, commercial interests, doctors, homeopathy, meta-analysis, methodology, pseudo-science, quackery, satire, systematic review | 20 Comments
Is Reiki effective? The researchers say yes, but I am far from convinced
Published Thursday 29 March 2018
Reiki is a Japanese technique administered by "laying on hands" and is based on the idea that an unseen "life force energy" flows through us and is what causes us to be alive. If one's "life force energy" is low, then we are more likely to get sick or feel stress, and if it is high, we are more capable of being happy and healthy (because it is such a clear-cut case of nonsense, we have discussed Reiki regularly; see for instance here, here, here, here, here, here, and here).
But nonsense does not stop researchers from conducting trials. In this new clinical trial, conducted in Physiotherapy Clinic of Khatam Al-Anbia Hospital in Iran, 60 patients with pain due to inter-vertebral disc herniation (IVDH) were randomly assigned to one of three groups.
The Reiki group received three 15-minute Reiki sessions on consecutive days by a master of Reiki plus Indomethacin and Methocarbamol (as in group 3).
The physiotherapy group underwent 7 to 10 sessions of physiotherapy of 60 to 90 minutes (heat therapy, TENS, pelvic traction, and physical exercises) plus Indomethacin and Methocarbamol (as in group 3).
The drug group received Indomethacin capsules 75 mg and Methocarbamol tablets 500 mg every 8 hours daily for one week.
The severity of pain and the activities of daily living (ADL) were measured using visual analogue scales (VAS) and ADL-Instrumental ADL questionnaire before and after the intervention. A significant difference was found in pain intensity and ADL improvement between Reiki and the drug therapy. No significant difference between the Reiki and physiotherapy groups were noted.
The authors concluded that Reiki and physiotherapy are effective methods in managing pain and improving ADL in patients with IVDH; however, Reiki is more cost-effective and faster treatment method than physiotherapy.
This RCT seems fairly well-panned and conducted, and its results are straight forward. My only problem with it is how the findings are interpreted.
The study design was such that there was no blinding or control for placebo effects. Therefore, the observed outcomes can be interpreted in more than one way. In my view, by far the most plausible explanation is that Reiki (being an exotic, impressive intervention that generates plenty of expectation) produced a powerful placebo effect. Physiotherapy (being entirely normal and routine), on the other hand, was only marginally successful. It is regrettable that the authors do not even consider this interpretation of their results. They should have remembered that a clinical trial test the null-hypothesis (the experimental treatment is not better that the comparator) which can be rejected only, if there is no other reasonable explanation for the results produced.
If I am correct, the conclusions should be re-written as follows:
The addition of Reiki to drug treatment generated better outcomes than drug therapy alone. Physiotherapy was only marginally effective. The effects of Reiki are most likely not due to the treatment per se but to a classical placebo response.
Posted in alternative medicine, back pain, causation, clinical trial, critical thinking, pain, physiotherapists, pseudo-science, Reiki | 16 Comments
INSPIRAL PAEDIATRIC SEMINARS … chiropractic quackery at its most obvious
Published Wednesday 28 March 2018
Chiropractic for kids? Yes, many chiropractors advocate (and earn good money with) it, yet it has been pointed out ad nauseam that the claim of being able of treating paediatric conditions is bogus (in fact, the BCA even lost a famous court case over this issue). But evidence does rarely seem to stop a chiro on a mission!
This website shows us how UK chiropractors plan to educate colleagues in 'paediatric chiropractic'.
START OF QUOTE
INSPIRAL PAEDIATRIC SEMINARS ……..KIDS DYNAMIC DEVELOPMENT
Join us for an exciting weekend of learning and skills development, in a supportive, enjoyable environment
Learn the latest in Chiropractic Paediatrics from two world class leaders whose seminars receive rave reviews & letters of gratitude
Increase your confidence and certainty in working with families in your community
Fri 7th September 2-6pm, Sat 8th 9-6pm, Sun 9th 9-1pm I
Investment £649 Earlybird ends August 15th Late fee £679
Inclusions: Notes, Lunch on Saturday, onsite parking Park Inn Hotel, Bath Rd, Sipson, Heathrow UB7 0DU
The seminar offers a neurological approach to healthy development in babies & children. It provides clinically relevant assessment, adjusting & clinical decision making. The focus will be on a Chiropractic wellness paradigm with a collaborative approach to promote healthy outcomes across the infant to adolescent years.
SAFE ADJUSTING
This is a hands-on program with a focus on neuro – developmentally appropriate adjusting of the spine and cranial dural system for health. We address some of the leading challenges with infant health and development, and teach exciting home care plans to facilitate optimum development.
YOUR TEACHERS
Genevieve & Rosemary Keating are leaders in Chiropractic paediatric health, learning & development.
Both are experienced Chiropractors, Facilitators, Diplomates of the American Chiropractic Neurology Board and Master Practitioners of Neuro Linguistics.
Rosemary holds a Masters in Chiropractic Paediatrics, and Genevieve is completing her PhD in Early Childhood Development.
The event is hosted and organised by the 'United Chiropractic Association UK' (UCA), an organisation with a mission to ensure the public has access to vitalistic chiropractic care, which claims that chiropractors provide care that is safe. Because the techniques used by chiropractors are acquired over years of study and experience, chiropractors have an enviable safety record. In fact, in the words of a classic New Zealand study, chiropractic care is "remarkably safe." Chiropractors use the latest methods. After years of study, licensing examinations and continuing education seminars, chiropractors in the United Kingdom are at the top of their game, using proven techniques and natural methods to help you get well and stay well.
The UCA is firmly rooted in the gospel of the founding fathers (D D Palmer, B J Palmer etc.): Chiropractic is concerned with the preservation and restoration of health, and focuses particular attention on the subluxation. A subluxation is a complex of functional and/or structural and/or pathological articular changes that compromise neural integrity and may influence organ system function and general health. A subluxation is evaluated, diagnosed, and managed through the use of chiropractic procedures based on the best available rational and empirical evidence. Subluxation is a fundamental axiom of the Chiropractic profession. The World Federation of Chiropractors (WFC) policy statement reaffirms the use of the term vertebral subluxation and it is defined succinctly and accepted by the World Health Organisation (WHO).
Thus, the UCA seems to subscribe to both principles of the Palmers. The first is subluxation and the second is profit.
Now, now, now – I must not be so sarcastic.
Try something constructive, Edzard!
You are absolutely correct, Edzard.
Here it is, my constructive contribution to this event:
I herewith offer the UCA to give two lectures during their course; one about the importance of critical thinking in healthcare, and one reviewing the evidence for and against chiropractic for paediatric conditions.
Posted in alternative medicine, children, chiropractic, commercial interests, critical thinking, education, medical ethics, progress, spinal manipulation | 9 Comments
Exaggerations and untruths in the promotion of homeopathy
Published Tuesday 27 March 2018
There seem to be plenty of myths and misunderstandings about homeopathy in India.
Homeopathy was first introduced to India by a German doctor from Siebenbuergen, Martin Honigberger (1795 – 1869). He first came to India in 1829 as a conventionally trained physician and treated amongst other personalities the Maharaja Ranjit Singh of Punjab. In 1834, he returned to Europe, met Hahnemann, and became a convert of homeopathy. Subsequently he returned to India, in 1839, and brought homeopathy to this country. Initially, homeopathy was practised mainly by lay practitioners. Mahendra Lal Sircar is said to have been the first Indian who became a homeopathic physician, and he is often called the 'Hering of India'. The 'Calcutta Homeopathic Medical College' was established in 1881 and assumed a crucial role in popularising homeopathy.
Today, we are often being told that homeopathy is incredibly popular in India. For instance, the HINDUSTAN TIMES recently published the following article:
The government on Tuesday said homeopathy is 'clinically effective' and there has been a 50 % rise in the number of patients seeking homeopathic treatment in the country in the past five years.
"In India, at 23 Institutes/ Units under the Central Council for Research in Homeopathy (CCRH), there is 50 % more footfall of patients seeking homeopathic treatment during the last five years," said AYUSH Minister of State (Independent Charge) Shripad Yesso Naik.
"Homeopathy is not a pseudoscience. The conclusion of most comprehensive systematic reviews of studies based on classical homeopathy has concluded that it has a positive and specific effect greater than placebo alone," he said in a written reply in the upper house.
"Homeopathy is being promoted as it is not only safe and effective but also due to its high acceptance through high quality surveys of use of homeopathy," said Naik, adding that there is evidence that homeopathy is beneficial.
"There is evidence based data (not anecdotal) with CCRH that warrants the promotion or acceptance of homeopathy in India," said the Minister.
In my view, this foremost begs one question: How does Shripad Yesso Naik get away with evidently false statements?
The minister describes himself as a 'business person' (not sure what this means, but it clearly does not describe a medical expert). Wikipedia has this interesting information on him: On March 25, 2016, Shripad Naik publicly stated he had access to research which proved that diseases such as cancer could be cured by yoga. He further stated that his Ministry was a year away from granting an endorsement to such techniques and research. The statement was challenged by medical researchers and doctors, who advocated caution in claiming a cure to cancer on the basis of unproven and unpublished research.
The AUYSH-ministry (AYUSH stands for ayurveda, yoga, siddha and homeopathy) seems to have the purpose of promoting homeopathy not on the basis of evidence but despite the evidence. For that purpose, it has set up a committee at the Central Council for Research in Homeopathy (CCRH) to "deal with issues related to false propaganda against homeopathy". They claim to have written to Nobel laureate Venkatraman Ramakrishnan, who correctly stated that homeopathy and astrology were "bogus"… "No one in chemistry believes in homeopathy. It works because of placebo effect". The director general of the CCRH countered that "The propaganda is coming from the West and it is picked up by newspapers here. They present homeopathy in a disproportionate and negative light, and it creates confusion… " The CCRH has also been writing letters, rejoinders and counter-editorials to others to combat "false propaganda."
I do not need to repeat here the evidence on homeopathy (we have dealt with it regularly on this blog); suffice to state that it fails to show that highly diluted homeopathic remedies differ from placebos. This, in turn, means that the accusation of 'false propaganda' must be directed not at the sceptics but at the AYUSH-ministry.
And what about the claim that homeopathy is currently so hugely popular in India? It seems that it is bogus too. A recent survey conducted by 'Indian National Sample Survey Office' revealed that 90% of the Indian population rely on conventional medicine. Merely 6% trust what the investigators chose to call 'Indian systems of medicine', e. g. ayurveda, yoga, siddha and homeopathy, often abbreviated as AYUSH.
The message that seems to emerge from all this is that, in India, homeopathy is being promoted on the basis of exaggerations and untruths – much like in many other countries, I hasten to add.
Chiropractors are being educated to become a danger to public health
Published Monday 26 March 2018
Chiropractors are fast giving up the vitalistic and obsolete concepts of their founding fathers, we are told over and over again. But are these affirmations true? There are good reasons to be sceptical. Take this recent paper, for instance.
The objective of this survey was to investigate the proportion of Australian chiropractic students who hold non-evidence-based beliefs in the first year of study and to determine the extent to which they may be involved in non-musculoskeletal health conditions.
Students from two Australian chiropractic programs were invited to answer a questionnaire on how often they would give advice on 5 common health conditions in their future practices, as well as to provide their opinion on whether chiropractic spinal adjustments could prevent or help seven health-related conditions.
The response rate of this survey was 53%. Students were highly likely to offer advice on a range of non-musculoskeletal conditions. The proportions were lowest in first year and highest the final year. For instance, 64% of students in year 4/5 believed that spinal adjustments improve the health of infants. Also, high numbers of students held non-evidence-based beliefs about 'chiropractic spinal adjustments' which tended to occur in gradually decreasing in numbers in sequential years, except for 5th and final year, when a reversal of the pattern occurred.
The authors concluded that new strategies are required for chiropractic educators if they are to produce graduates who understand and deliver evidence-based health care and able to be part of the mainstream health care system.
This is an interesting survey, but I think its conclusion is wrong!
Educators do not require 'new strategies', I would argue; they simply need to take their duty of educating students seriously – educating in this context does not mean brain-washing, it means teaching facts and evidence-based practice. And this is were any concept of true education would run into problems: it would teach students that chiropractic is built on sand.
Conclusions need to be based on the data presented. Therefore, the most fitting conclusion, in my view, is that chiropractic students are currently being educated such that, once let loose on the unsuspecting and often all too gullible public, they will be a menace and a serious danger to public health.
You might say that this survey is from Australia and that the findings therefore do not necessarily apply to other countries. Correct! However, I very much fear that elsewhere the situation is similar or perhaps even worse. And my fear does not come out of thin air, it is based on things we have discussed before; see for instance these three posts:
Chiropractic education seems to be a form of religious indoctrination
What are the competencies of a 'certified paediatric doctor of chiropractic'?
Educating chiros
But I would be more than willing to change my mind – provided someone can show me good evidence to the contrary.
Posted in alternative therapist, bias, charlatan, chiropractic, conflict of interest, critical thinking, education, medical ethics, risk, survey | Leave a comment
'Doctors turn to herbal cures when the drugs don't work' … THE TIMES is wallowing in nonsense
Published Sunday 25 March 2018
An article in yesterday' Times makes the surprising claim that 'doctors turn to herbal cures when the drugs don't work'. As the subject is undoubtedly relevant to this blog and as the Times is a highly respected newspaper, I think this might be important and will therefore comment (in normal print) on the full text of the article (in bold print):
GPs are increasingly dissatisfied with doling out pills that do not work for illnesses with social and emotional roots, and a surprising number of them end up turning to alternative medicine.
What a sentence! I would have thought that GPs have always been 'dissatisfied' with treatments that are ineffective. But who says they turn to alternative medicine in 'surprising numbers' (our own survey does not confirm the notion)? And what is a 'surprising number' anyway (zero would be surprising, in my view)?
Charlotte Mendes da Costa is unusual in being both an NHS GP and a registered homeopath. Her frustration with the conventional approach of matching a medicine to a symptom is growing as doctors increasingly see the limits, and the risks, of such a tactic.
Do we get the impression that THE TIMES does not know that homeopathy is not herbal medicine? Do they know that 'matching a medicine to a symptom' is what homeopaths believe they are doing? Real doctors try to find the cause of a symptom and, whenever possible, treat it.
She asks patients with sore throats questions that few other GPs pose: "What side is it? Is it easier to swallow solids or liquids? What time of day is it worst?" Dr Mendes da Costa is trying to find out which homeopathic remedy to prescribe. But when NHS guidance for sore throats aims mainly to convince patients that they will get better on their own, her questions are just as important as her prescription.
This section makes no sense. Sore throats do get better on their own, that's a fact. And empathy is not a monopoly of homeopaths. But Dr Mendes Da Costa might be somewhat detached from reality; she once promoted the nonsensical notion that "up to the end of 2010, 156 randomised controlled trials (RCTs) in homeopathy had been carried out with 41% reporting positive effects, whereas only 7% have been negative. The remainder were non-conclusive." (see more on this particular issue here)
"It's very difficult to disentangle the effect of listening to someone properly, in a non-judgmental way, and taking a real rather than a superficial interest," she says. "With a sore throat [I was trained] really only to be interested in, 'Do they need antibiotics or not?' "
In this case, she should ask her money back; her medical school seems to have been rubbish in training her adequately.
This week a Lancet series on back pain said that millions of patients were getting treatments that did them no good. A government review is looking into how one in 11 people has come to be on potentially addictive drugs such as tranquillisers, opioid painkillers and antidepressants.
Yes, and how is that an argument for homeopathy? It isn't! It seems to come from the textbook of fallacies.
And this week a BMJ Open study found that GPs with alternative training prescribed a fifth fewer antibiotics.
That study was akin to showing that butchers sell less vegetables than green-grocers. It provided no argument at all for implying that homeopathy is a valuable therapy.
Doctors seem receptive to alternative approaches: in a poll on its website 70 per cent agreed that doctors should recommend acupuncture to patients in pain. The Faculty of Homeopathy now counts 400 doctors among its 700 healthcare professional members.
Wow! Does the Times journalist know that the 'Faculty of Homeopathy' is primarily an organisation for doctor homeopaths? If so, why are these figures anything to write home about? And does the author appreciate that the pole was open not just to doctors but to to anyone (particularly those who were motivated, like acupuncturists)?
This horrifies many academics, who say that there is almost no evidence that complementary therapies work.
It horrifies nobody, I'd say. It puzzles some people, and not just academics. And their claim of a lack of sound evidence is evidence-based.
"It's a false battle", says Michael Dixon, a GP who chairs the College of Medicine, which is trying to broaden the focus on treatment to patients' whole lives. "GPs are practical. If a patient gets better that's all that matters."
Here comes the inevitable Dr Dixon (the 'pyromaniac in a field of straw-men') with the oldest chestnut in town. But repeating a nonsense endlessly does not render it sensible.
Dr Dixon says there are enormous areas of illness ranging from chronic pain to irritable bowels where few conventional treatments have been shown to be particularly effective, so why not try alternatives with fewer side effects?
Unable to diagnose and treat adequately, let's all do the next worst thing and apply some outright quackery?!? Logic does not seem to be Dixon's strong point, does it?
He recommends herbal remedies such as pelargonium — "like a geranium, quite a pretty little flower" — acupressure, and techniques such as self-hypnosis. To those who say these are placebos he replies: so what?
So what indeed! There are over 200 species of pelargonium; only 2 or 3 of them are used in herbal medicine. I don't suppose Dr Dixon wants to poison us?
"Aromatherapy does work, but only if you believe in it, that's the way you have to look at it, like a mother kissing knees better." He continues: "We are healers. That's what we do as doctors. You can call it theatrical or you can call it a relationship. A lot of patients come in with a metaphor — a headache is actually unhappiness — and the treatment is symbolic."
It frightens me to know that there are doctors out there who think like this!
What if a patient is seriously ill?
A cancer is a metaphor for what exactly?
As doctors, we have the ethical duty to apply BOTH the science and the art of medicine, BOTH efficacious, evidence-based therapies AND compassion. Can I be so bold as to recommend our book about the ethics of alternative medicine to Dixon?
Such talk makes conventional doctors very nervous. Yet acupuncture illustrates their dilemma. It used to be recommended by the NHS for back pain because patients did improve. Now it is not, after further evidence suggested that patients given placebo "sham acupuncture" did just as well.
No, acupuncture used to be recommended by NICE because there was some evidence; when subsequently more rigorous trials emerged showing that it does NOT work, NICE stopped recommending it. Real medicine develops – it's only alternative medicine and its proponents that seem to be stuck in the past and resist progress.
Martin Underwood, of the University of Warwick, asks: "So are you going to say, 'Well, patients get better than they would do otherwise'? Or say it's all theatrical placebo because it shows no benefit over sham treatment? That's the question for society."
Society has long answered it! The answer is called evidence-based medicine. We are not content using quackery for its placebo response; we know that effective treatments do that too, and we want to make progress and improve healthcare of tomorrow.
Although many doctors agree that they need to look at patients more broadly, they insist they do not need to turn to unproven treatments. The magic ingredient, they say, is not an alternative remedy, but time. Helen Stokes-Lampard, chairwoman of the Royal College of GPs, said: "Practices which offer alternative therapies tend to spend longer with patients . . . allowing for more in-depth conversations."
I am sorry, if this post turned into a bit of a lengthy rant. But it was needed, I think: if there ever was a poorly written, ill focussed, badly researched and badly argued article on alternative medicine, it must be this one.
Did I call the Times a highly respected paper?
I take it back.
Posted in acupuncture, alternative medicine, aromatherapy, back pain, bias, bogus claims, charlatan, conflict of interest, fallacy, herbal medicine, homeopathy, medical ethics, Michael Dixon, pain, quackery, risk | 22 Comments
Low back pain: alternative practitioners feel encouraged by the recent Lancet-articles – wrongly so, I hasten to add
Published Saturday 24 March 2018
The media have (rightly) paid much attention to the three Lancet-articles on low back pain (LBP) which were published this week. LBP is such a common condition that its prevalence alone renders it an important subject for us all. One of the three papers covers the treatment and prevention of LBP. Specifically, it lists various therapies according to their effectiveness for both acute and persistent LBP. The authors of the article base their judgements mainly on published guidelines from Denmark, UK and the US; as these guidelines differ, they attempt a synthesis of the three.
Several alternative therapist organisations and individuals have consequently jumped on the LBP bandwagon and seem to feel encouraged by the attention given to the Lancet-papers to promote their treatments. Others have claimed that my often critical verdicts of alternative therapies for LBP are out of line with this evidence and asked 'who should we believe the international team of experts writing in one of the best medical journals, or Edzard Ernst writing on his blog?' They are trying to create a division where none exists,
The thing is that I am broadly in agreement with the evidence presented in Lancet-paper! But I also know that things are a bit more complex.
Below, I have copied the non-pharmacological, non-operative treatments listed in the Lancet-paper together with the authors' verdicts regarding their effectiveness for both acute and persistent LBP. I find no glaring contradictions with what I regard as the best current evidence and with my posts on the subject. But I feel compelled to point out that the Lancet-paper merely lists the effectiveness of several therapeutic options, and that the value of a treatment is not only determined by its effectiveness. Crucial further elements are a therapy's cost and its risks, the latter of which also determines the most important criterion: the risk/benefit balance. In my version of the Lancet table, I have therefore added these three variables for non-pharmacological and non-surgical options:
EFFECTIVENESS ACUTE LBP EFFECTIVENESS PERSISTENT LBP RISKS COSTS RISK/BENEFIT BALANCE
Advice to stay active +, routine +, routine None Low Positive
Education +, routine +, routine None Low Positive
Superficial heat +/- Ie Very minor Low to medium Positive (aLBP)
Exercise Limited +/-, routine Very minor Low Positive (pLBP)
CBT Limited +/-, routine None Low to medium Positive (pLBP)
Spinal manipulation +/- +/- vfbmae
sae High Negative
Massage +/- +/- Very minor High Positive
Acupuncture +/- +/- sae High Questionable
Yoga Ie +/- Minor Medium Questionable
Mindfulness Ie +/- Minor Medium Questionable
Rehab Ie +/- Minor Medium to high Questionable
Routine = consider for routine use
+/- = second line or adjunctive treatment
Ie = insufficient evidence
Limited = limited use in selected patients
vfbmae = very frequent, minor adverse effects
sae = serious adverse effects, including deaths, are on record
aLBP = acute low back pain
The reason why my stance, as expressed on this blog and elsewhere, is often critical about certain alternative therapies is thus obvious and transparent. For none of them (except for massage) is the risk/benefit balance positive. And for spinal manipulation, it even turns out to be negative. It goes almost without saying that responsible advice must be to avoid treatments for which the benefits do not demonstrably outweigh the risks.
I imagine that chiropractors, osteopaths and acupuncturists will strongly disagree with my interpretation of the evidence (they might even feel that their cash-flow is endangered) – and I am looking forward to the discussions around their objections.
Posted in acupuncture, alternative medicine, alternative therapist, back pain, bias, chiropractic, commercial interests, conflict of interest, critical thinking, death, EBM, economic evaluation, evidence, guideline, massage, methodology, pain, physiotherapists, risk, risk/benefit, spinal manipulation, symptom-relief, yoga | 30 Comments
A new RCT of homeopathy … and, guess what, it reports a positive result (but are we being misled or not?)
Homeopathy works!
At least this is what the authors of this new study want us to believe.
But are they right?
This RCT is entitled 'Efficacy and tolerability of a complex homeopathic drug in children suffering from dry cough-A double-blind, placebo- controlled, clinical trial'. It recruited children suffering from acute dry cough to assess the efficacy and tolerability of a complex homeopathic remedy in liquid form (Drosera, Coccus cacti, Cuprum Sulfuricum, Ipecacuanha = Monapax syrup, short: verum).
The authors stated that "preparations of Drosera, Coccus cacti, Cuprum sulfuricum, and Ipecacuanha are well-known antitussives in homeopathic medicine. Each of them is connected with special subtypes of cough. Drosera is intended for inflammations of the respiratory tract, especially for whooping cough. Coccus cacti is intended for inflammations of the nasopharyngeal space and the respiratory tract. Cuprum sulfuricum is intended for spasmodic coughing at night. Ipecacuanha is intended for bronchitis, bronchial asthma, and whooping cough. The complex homeopathic drug explored in this trial consists of all four of these active substances."
According to the authors of the paper, "the primary objective of the trial was to demonstrate the superiority of verum compared to the placebo".
A total of 89 children, enrolled in the Ukraine between 15/04/2008 and 26/05/2008 in 9 trial centres, received verum and 91 received placebo daily for 7 days (age groups 0.5–3, 4–7 and 8–12 years). The trial was conducted using an adaptive 3-stage group sequential design with possible sample size adjustments after the two planned interim analyses. The inverse normal method of combining the p-values from all three stages was used for confirmatory hypothesis testing at the interim analyses as well as at the final analysis. The primary efficacy variable was the improvement of the Cough Assessment Score. Tolerability and compliance were also assessed. A confirmatory statistical analysis was performed for the primary efficacy variable and a descriptive analysis for the secondary parameters.
A total of 180 patients (89 in the verum and 91 in the placebo group) evaluable according to the intention-to-treat principle were included in the trial. The Cough Assessment Score showed an improvement of 5.2 ± 2.6 points for children treated with verum and 3.2 ± 2.6 points in the placebo group (p < 0.0001). The difference of the least square means of the improvements was 1.9 ± 0.4. The effect size of Cohen´s d was d = 0.77. In all secondary parameters the patients in the verum group showed higher rates of improvement and remission than those in the placebo group. In 15 patients (verum: n = 6; placebo: n = 9) 18 adverse drug reactions of mild or moderate intensity were observed.
The authors concluded that the administering verum resulted in a statistically significantly greater improvement of the Cough Assessment Score than the placebo. The tolerability was good and not inferior to that of the placebo.
This study seems fairly rigorous. What is more, it has been published in a mainstream journal of reasonably high standing. So, how can its results be positive? We all know that homeopathy does not work, don't we?
Are we perhaps mistaken?
Are highly diluted homeopathic remedies effective after all?
Let me explain to you a few points that raise my suspicions about this study:
It was conducted 10 years ago; why did it take that long to get it published?
I don't think highly of a study with "the primary objective … to demonstrate the superiority" of the experimental interventions. Scientists use RCTs for testing efficacy and pseudo-scientist use it for demonstrating it, I think.
The study was conducted in the Ukraine in 9 centres, yet no Ukrainian is an author of the paper, and there is not even an acknowledgement of these primary investigators.
The 'adaptive 3-stage group sequential design with possible sample size adjustments' sounds very odd to me, but I may be wrong; I am not a statistician.
We learn that 180 patients were evaluated, but not how many were entered into the trial?
The Cough Assessment Score is not a validated outcome measure.
Was the verum distinguishable from the placebo? It would be easy to test whether the patients/parents were truly blinded. Yet no such results were included.
The trial was funded by the manufacturer of the homeopathic remedy.
The paper has three authors 1)Hans W. Voß has no conflict of interest to declare. 2) Rainer Brünjes is employed at Cassella-med, the marketing authorisation holder of the study product. 3) Andreas Michalsen has consulted for Cassella-med and participated in advisory boards.
I know, homeopathy fans will think I am nit-picking; and perhaps they are correct. So, let me tell you why I really do strongly reject the notion that this study shows or even suggests that highly diluted homeopathic remedies are more than placebos.
The remedy used in this study is composed of Drosera 0,02 g, Hedera helix Ø 0,04 g, China D1 0,02 g, Coccus cacti D1 0,04 g, Cuprum sulfuricum D4 2,0 g, Ipecacuanha D4 2,0 g, Hyoscyamus D4 2,0 g.
In case you don't know what 'Ø' stands for (I don't blame you, hardly anyone outside the world of homeopathy does), it signifies a 'mother tincture', i. e. an undiluted herbal extract; and 'D1' signifies diluted 1:10. This means that the remedy may be homeopathic from a regulatory point of view, but for all intents and purposes it is a herbal medicine. It contains an uncounted amount of active compounds, and it is therefore hardly surprising that it might have pharmacological effects. In turn, this means that this trial does by no means overturn the fact that highly diluted homeopathic remedies are pure placebos.
It's a pity, I find, that the authors of the paper fail to explain this simple fact in full detail – might one think that they intentionally aimed at misleading us?
Posted in alternative medicine, bias, children, clinical trial, commercial interests, critical thinking, herbal medicine, homeopathy, methodology | 10 Comments
Suffering from back pain? Walk to your therapist, don't accept (or pay for) treatment, but walk straight back home again
We all know that there is a plethora of interventions for and specialists in low back pain (chiropractors, osteopaths, massage therapists, physiotherapists etc., etc.); and, depending whether you are an optimist or a pessimist, each of these therapies is as good or as useless as the next. Today, a widely-publicised series of articles in the Lancet confirms that none of the current options is optimal:
Almost everyone will have low back pain at some point in their lives. It can affect anyone at any age, and it is increasing—disability due to back pain has risen by more than 50% since 1990. Low back pain is becoming more prevalent in low-income and middle-income countries (LMICs) much more rapidly than in high-income countries. The cause is not always clear, apart from in people with, for example, malignant disease, spinal malformations, or spinal injury. Treatment varies widely around the world, from bed rest, mainly in LMICs, to surgery and the use of dangerous drugs such as opioids, usually in high-income countries.
The Lancet publishes three papers on low back pain, by an international group of authors led by Prof Rachelle Buchbinder, Monash University, Melbourne, Australia, which address the issues around the disorder and call for worldwide recognition of the disability associated with the disorder and the removal of harmful practices. In the first paper, Jan Hartvigsen, Mark Hancock, and colleagues draw our attention to the complexity of the condition and the contributors to it, such as psychological, social, and biophysical factors, and especially to the problems faced by LMICs. In the second paper, Nadine Foster, Christopher Maher, and their colleagues outline recommendations for treatment and the scarcity of research into prevention of low back pain. The last paper is a call for action by Rachelle Buchbinder and her colleagues. They say that persistence of disability associated with low back pain needs to be recognised and that it cannot be separated from social and economic factors and personal and cultural beliefs about back pain.
Overview of interventions endorsed for non-specific low back pain in evidence-based clinical practice guidelines (Danish, US, and UK guidelines)
In this situation, it makes sense, I think, to opt for a treatment (amongst similarly effective/ineffective therapies) that is at least safe, cheap and readily available. This automatically rules out chiropractic, osteopathy and many others. Exercise, however, does come to mind – but what type of exercise?
The aim of this meta-analysis of randomized controlled trials was to gain insight into the effectiveness of walking intervention on pain, disability, and quality of life in patients with chronic low back pain (LBP) at post intervention and follow ups.
Six electronic databases (PubMed, Science Direct, Web of Science, Scopus, PEDro and The Cochrane library) were searched from 1980 to October 2017. Randomized controlled trials (RCTs) in patients with chronic LBP were included, if they compared the effects of walking intervention to non-pharmacological interventions. Pain, disability, and quality of life were the primary health outcomes.
Nine RCTs were suitable for meta-analysis. Data was analysed according to the duration of follow-up (short-term, < 3 months; intermediate-term, between 3 and 12 months; long-term, > 12 months). Low- to moderate-quality evidence suggests that walking intervention in patients with chronic LBP was as effective as other non-pharmacological interventions on pain and disability reduction in both short- and intermediate-term follow ups.
The authors concluded that, unless supplementary high-quality studies provide different evidence, walking, which is easy to perform and highly accessible, can be recommended in the management of chronic LBP to reduce pain and disability.
I know – this will hardly please the legions of therapists who earn their daily bread with pretending their therapy is the best for LBP. But healthcare is clearly not about the welfare of the therapists, it is/should be about patients. And patients should surely welcome this evidence. I know, walking is not always easy for people with severe LBP, but it seems effective and it is safe, free and available to everyone.
My advice to patients is therefore to walk (slowly and cautiously) to the office of their preferred therapist, have a little rest there (say hello to the staff perhaps) and then walk straight back home.
Posted in alternative medicine, alternative therapist, back pain, chiropractic, education, evidence, massage, meta-analysis, osteopathy, pain, physiotherapists, risk, spinal manipulation, systematic review | 51 Comments
Prof Frass' criticism of the Lancet meta-analysis of homeopathy: a rebuttal of a rebuttal
by Norbert Aust as 'guest blogger' and Edzard Ernst
Professor Frass has repeatedly stated that his published criticism of the Lancet meta-analysis has never been refuted, and therefore homeopathy is a valid therapy. The last time we heard him say this was during a TV discussion (March 2018) where he said that, if one succeeded in scientifically refuting the arguments set out in his paper, one would show the ineffectiveness of homeopathy.
In today's post, we quote the paper Frass refers to, published as a 'letter to the editor' (published in the journal Homeopathy) by Frass et al (bold typing), and provide our rebuttal (in normal print) of it:
Even with careful selection, it remains problematic to compare studies of a pool of 165 for homeopathy vs 4200,000 for conventional medicine. This factor of 41000 already contains asymmetry.
We see no good reasons why the asymmetry poses a problem; it does not conceivably impact on the outcome, nor does it bias the results. In fact, such asymmetries are common is research.
Furthermore, it appears that there is discrimination when publications in English (94/110, 85% in the conventional medicine group vs 58/110, 53% in the homeopathy group) are rated higher quality (Table 2).
We cannot confirm that the table demonstrates such a discrimination, nor do we understand how this would disadvantage homeopathy.
Neither the Summary nor the Introduction clearly specify the aim of the study.
The authors stated that they "analysed trials of homoeopathy and conventional medicine and estimated treatment effects in trials least likely to be affected by bias". It is hardly difficult to transform this into their aim: the authors aimed at analysing trials of homoeopathy and conventional medicine and estimating treatment effects in trials least likely to be affected by bias.
Furthermore, the design of the study differs substantially from the final analysis and therefore the prolonged description of how the papers and databases were selected is misleading: instead of analysing all 110 studies retrieved by their defined inclusion and exclusion criteria, the authors reduce the number of investigated studies to 'larger trials of higher quality'. By using these sub-samples, the results seem to differ between conventional medicine and homeopathy.
This statement discloses a misconception of the approach used in the meta-analysis. The meta-analysis of all 110 trials found some advantages of homeopathy. When the authors performed a sensitivity analysis with high quality and larger studies, this advantage disappeared. The sensitivity analysis was to determine whether the overall treatment effect seen in the initial analysis was real or false-positive. In the case of homeopathy, it turned out to be false (and presumably for this reason, the authors hardly mention it in their paper), whereas for the trials of conventional medicines, it was real. This procedure is in keeping with the authors' stated aims.
The meta-analysis does not compare studies of homeopathy vs studies of conventional medicine, but specific effects of these two methods in separate analyses. Therefore, a direct comparison must not be made from this study.
We fail to see the significance in terms of the research question stated by the authors. Even Frass et al use direct comparisons above.
However, there remains great uncertainty about the selection of the eight homeopathy and the six conventional medicine studies: the cut-off point seems to be arbitrarily chosen: if one looks at Figure 2, the data look very much the same for both groups. This holds true even if various levels of SE are considered. Therefore, the selection of larger trials of higher quality is a post-festum hypothesis but not a pre-set criterion.
This is not true, Shang et al clearly stated in their paper: "Trials with SE (standard error) in the lowest quartile were considered larger trials." It is common, reasonable and in keeping with the authors' aims to conduct sensitivity analyses using a subset of trials that seem more reliable than the average.
The question remains: was the restriction to larger trials of higher quality part of the original protocol or was this a data-driven decision? Since we cannot find this proposed reduction in the abstract, we doubt that it was included a priori.
We are puzzled by this statement and fail to understand why Frass et al insist that this information should have been in the abstract.
However, even if one assumes that this was a predefined selection, there are still some problems with the authors' interpretation: for larger trials of higher reported methodological quality, the odds ratio was 0.88 (CI 95%: 0.65–1.19) based on eight trials of homeopathy: although this finding does not prove an effect of the study design on the 5% level, neither does it disprove the hypothesis that the results might have been achieved by homeopathy. For conventional medicine, the odds ratio was 0.58 (CI 95% 0.39–0.85), which indicates that the results may not be explained by mere chance with a 5% uncertainty.
As the outcome failed to reach the level of significance, the null-hypothesis ("there is no difference") cannot be discarded, and this is sufficient evidence to show that there is no evidence for the effectiveness of homeopathy. The comment by Frass et al seems to be based on a misunderstanding how science operates.
Although the authors acknowledge that 'to prove a negative is impossible' the authors clearly favour the view that there is evidence that homoeopathy exhibits no effect beyond the placebo-effect. However, this conclusion was drawn after a substantial modification of the original protocol which considerably weakens its validity from the methodological point of view. After acquiring the trials by their original inclusion- and exclusion criteria they introduced a further criterion, 'larger trials of higher reported methodological quality'. Thus, eight trials (=46% of the larger trials) in the homoeopathy group were left and only six (32%) in conventional medicine group (an odds ratio of 0.75 in favour of homoeopathy).
As explained above, the authors' reasoning was clear and rational; it did not follow the logic suggested by Frass et al. which confirms our suspicion already mentioned above that Frass et al misunderstood the concept of the Shang meta-analysis.
But the decisive point is that it is unlikely that these six trials are still matched to the eight samples of homoeopathy (although each of the 110 in the original was matched). Consequently, one cannot conclude that these trials are still comparable. Thus, any comparisons of results between them are unjustified.
Further evidence that Frass et al misunderstood the concept of the Shang meta-analysis.
The rationale for this major alteration of the study protocol was the assumption, that these larger, higher quality trials are not biased, but no evidence or databased justification is given. Neither the actual data (odds ratio, matching parameters…) nor a funnel plot (to indicate that there is no bias) of the final 14 trials are supplied although these parameters constitute the ground of their conclusion.
The other 206 trials (94% of the originally selected according to the protocol) were discarded because of possible publication biases as visualized by the funnel plots. However, the use of funnel plots is also questionable. Funnel plots are thought to detect publication bias, and heterogeneity to detect fundamental differences between studies.
New evidence suggests that both of these common beliefs are badly flawed. Using 198 published meta-analyses, Tang and Liu demonstrate that the shape of a funnel plot is largely determined by the arbitrary choice of the method to construct the plot. When a different definition of precision and/or effect measure was used, the conclusion about the shape of the plot was altered in 37 (86%) of the 43 meta-analyses with an asymmetrical plot suggesting selection bias. In the absence of a consensus on how the plot should be constructed, asymmetrical funnel plots should be interpreted cautiously.
These findings also suggest that the discrepancies between large trials and corresponding meta-analyses and heterogeneity in metaanalyses may also be determined by how they are evaluated. Researchers tend to read asymmetric funnel plots as evidence of publication bias, even though metaanalyses without publication bias frequently have asymmetric plots and meta-analysis with publication bias frequently have symmetric plots, simply due to chance.
Perhaps we should mention that the senior author of the Lancet meta-analysis, Mathias Egger, is the clinical epidemiologist who invented the funnel plot and certainly knows how to use and interpret it.
Use of funnel plots is even more unreliable when there is heterogeneity. Apart from the questionable selection of the samples there is a further aspect of randomness which further weakens their conclusion: the odds ratio of the eight trials of homoeopathy was 0.88 (CI 0.65–1.19), which might be significant around the 7–8% level. Actually, the reader might be interested to know at which exact level homeopathy would have become significant. Thus, there is no support of their conclusion any more when you shift the level of significance by mere, say 2–3%.
What number of grains is required to build a heap? Certainly there is such a limit. Five grains are not a heap, five billion are. But if you select any specific value, you will find it hard to explain if one grain less changes the characteristic of a heap to become a number of grains only. Same here. If p = 0.05 is the limit of significance, p = 0.05001 is not significant, let alone, when p is 2-3%higher than that.
In addition, with such controversial hypotheses the scientific community would tend to use a level of significance of 1% in which case the odds ratio of the conventional studies would not be significant either.
The level of 5% is commonly applied in medical research; it is the accepted standard. Frass et al also apply it in their studies; but here they want to change it. Why, to suit their preconceived ideas?
From a statistical point of view, the power of the test, considering the small sample sizes, should have been stated, especially in the case of a nonsignificant result.
This might have been informative but is rarely done in meta-analyses.
Above all, the choice of which trials are to be evaluated is crucial. By choosing a different sample of eight trials (eg the eight trials in 'acute infections of the upper respiratory tract', as mentioned in the Discussion section) a radically different conclusion would have had to be drawn (namely a substantial beneficial effect of homeopathy—as the authors state).
The authors may not be aware that larger trials are usually not 'classical' homeopathic interventions, because the main principle of homeopathy, individualization are difficult to apply in large trials. In this respect, the whole study lacks sound understanding of what homeopathy really is.
This is a red herring; firstly the authors did not aim to evaluate individualised homeopathy. Secondly, Frass et al know very well that clinical homeopathy is not individualised and regarded as entirely legitimate by homeopaths. And finally, the largest trial of individualised homeopathy included in Mathie's review of individualized homeopathy had 251 participants.
So, why has so far no rebuttal of this 'letter to the Editor' been published? We suspect that the journal Homeopathy has little incentive to publish a critical response, and critics of homeopathy have even less motivation to submit one to this journal. Other journals have no reason at all to pursue a discussion started in 'Homeopathy'. In other words, Frass et al were safe from any rebuttal – until today, that is.


text:
El Pic de l'Espasa és una muntanya de 1.531 metres que es troba entre els municipis de Farrera i de Llavorsí, a la comarca del Pallars Sobirà.

Referències

Muntanyes de Farrera
Muntanyes de Llavorsí

redpajama_set_name: RedPajamaWikipedia


text:
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A wonderful example of belle époque architecture, the Hotel Maria Cristina was designed by Charles Mewes, the architect responsible for the Ritz hotels in Paris and London. It first opened its doors in 1912; the first guest was the regent of Spain, Maria Cristina. Today, anyone can enter the lobby and admire the understated luxury, or browse the items on sale at the Mimo San Sebastián Gourmet Shop.


text:
Q: Can't re-order songs in iTunes 12 I'm almost embarrassed to post this: I can't re-order the songs in any playlists on my Mac. It's iTunes 12.1.0.50 on OSX Yosemite 10.10.2.
The playlists are all sorted in manual order. There doesn't appear to be anything wrong with them. They all play; each playlist, each song. It is a mixture of playlists I've created on this computer and ones I've synced from another. They are not shuffled. iTunes Match is enabled and not currently syncing. I've quit and restarted iTunes.
Just in case I've missed something, here's a screenshot:

Help me Ask Different, you're my only hope.

A: posted as answer to add pic…
This tells me it's shuffled right now; click it to turn off again.

Re-ordering should be as simple as dragging to a new position, but whilst it's shuffled it will appear to ignore you, as it's unlikely to recalculate the shuffle at that point.

A: Okay, so this is weird... OSX suddenly started to be unable to copy and paste in certain applications (Sublime Text 2 could cut/copy, but wouldn't paste anything, couldn't cut from Chrome then paste in Sublime, etc). I've had this issue before with Yosemite. I restarted, which I've used to fix the issue before.
Now I can re-order songs in iTunes. Related to clipboard stuff?! I'm at a total loss and don't feel like I've answered anything. Would love to get more insight into this.

A: I had the same issue. I discovered that my iPhone 5S was connected via Wi-fi. Once I disconnected it, control of everything in iTunes returned.

A: According to your screenshot, your sort order is with the numbers (position).  I feel bad to ask, but what happens if you clicked on the header for "Name", "Artist" or "Album"?  Does that sort them by name, artist and album respectively?

A: So here's what I did to shuffle the order of my playlist.

*

*Select all the songs you want in the playlist

*Edit all their info so they have a matching category (artist, album, grouping, etc.)

*Create a smart playlist with the rule to include all items containing whatever matching info you chose.

*Select the limit to [any number higher than the number of songs in your playlist] items option with items selected by random

*Select OK

*You should have a smart playlist with randomized order. You can now copy this to a regular playlist if you'd prefer not to use a smart playlist

A: I finally found the easy way to do this - on the top right corner you have a drop down list often set to 'Songs' or 'Playlist'. Just enter this menu and you can see the option 'Sort by'. Select 'Playlist order'. That should do it!

A: Go into edit and put say 1 of 5, 2 of 5, 3 of 5 and so on in compilation. It took me ages to work this out. Worked for me.

redpajama_set_name: RedPajamaStackExchange


text:
Q: Java Number format how to change +/- sign to custom text I would like to use number formatting for adding a text different when number is positive or negative
ex :

-3.5 => (down) 3.5
+3.5 => (up)   3.5

I have found things in DecimalFormatSymbols, but it's only possible to change minus sign and only for a single char
Is there any other simple way using number formater?
DecimalFormatSymbols unusualSymbols = new DecimalFormatSymbols(currentLocale);
unusualSymbols.setDecimalSeparator('|');
unusualSymbols.setGroupingSeparator('^');
unusualSymbols.setMinusSign();
String strange = "#,##0.###";
DecimalFormat weirdFormatter =
        new DecimalFormat(strange, unusualSymbols);
weirdFormatter.setGroupingSize(4);

String bizarre = weirdFormatter.format(12345.678);
System.out.println(bizarre);

A: Set the positive prefix and negative prefix of the DecimalFormat:
DecimalFormat formatter = new DecimalFormat();
formatter.setPositivePrefix("(up) ");
formatter.setNegativePrefix("(down) ");
System.out.println(formatter.format(-3.5));
System.out.println(formatter.format(3.5));

Output:
(down) 3.5
(up) 3.5

A: You can do this in your format string for DecimalFormat:
(up) #,##0.###;(down) #,##0.###

The linked doc contains a complete syntax definition for the format string, which starts:

Pattern:
         PositivePattern
         PositivePattern ; NegativePattern

This indicates that an optional second format string separated by a semicolon (;) will be used for negative values.
Reading further:

PositivePattern:
        Prefix_opt Number Suffix_opt
NegativePattern:
        Prefix_opt Number Suffix_opt
Prefix:
        any Unicode characters except \uFFFE, \uFFFF, and special characters
Suffix:
        any Unicode characters except \uFFFE, \uFFFF, and special characters

Each pattern (positive and negative) consists of a number format string (Number) with an optional prefix and suffix string. These additional parts can be any string you like (including (up) and (down)).


text:
Our Catalog Literature & Fiction British & Irish
Giordano Bruno and the Geometry of Language (Literary and Scientific Cultures of Early Modernity)
Mega Sale! Save 27% on the Giordano Bruno and the Geometry of Language (Literary and Scientific Cultures of Early Modernity) by Ashgate Publishing Co. at Translate This Website. Hurry! Limited time offer. Offer valid only while supplies last. Giordano Bruno and the Geometry of Language brings to the fore a sixteenth-century philosopher's role in early modern Europe as a bridge between science and literature, or more specifically, between the spatial paradigm of geometry and that of language. Arielle Saiber examines how, to invite what Bruno believed to be an infinite universe-its qualities and vicissitudes-into the world of language, Bruno forged a system of 'figurative' vocabularies: number, form, space, and word. This verbal and
Giordano Bruno and the Geometry of Language brings to the fore a sixteenth-century philosopher's role in early modern Europe as a bridge between science and literature, or more specifically, between the spatial paradigm of geometry and that of language. Arielle Saiber examines how, to invite what Bruno believed to be an infinite universe-its qualities and vicissitudes-into the world of language, Bruno forged a system of 'figurative' vocabularies: number, form, space, and word. This verbal and symbolic system in which geometric figures are seen to underlie rhetorical figures, is what Saiber calls 'geometric rhetoric.' Through analysis of Bruno's writings, Saiber shows how Bruno's writing necessitates a crafting of space, and is, in essence, a lexicon of spatial concepts. This study constitutes an original contribution both to scholarship on Bruno and to the fields of early modern scientific and literary studies. It also addresses the broader question of what role geometry has in the formation of any language and literature of any place and time.
Manufacturer: Ashgate Publishing Co.
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Wordsworth's Poetic Theory: Knowledge, Language, Experience
By Uhlig Stefan H Regier Alexander
ean: 9780230525443, isbn: 023052544X,
Together, Wordsworth's verse and his compelling criticism have done much to shape our understanding of poetic art since the Romantic period. This volume is the first in many years to reexamine Wordsworth's complex theory of poetry in depth across the full range of the poet's work, presenting new scholarship by influential commentators in the field.Wordsworth s Poetic Theory Knowledge Language Experience.
Language and Community in Early England: Imagining Distance in Medieval Literature (Routledge Studies in Medieval Literature and Culture)
By Ingramcontent
ean: 9781138676619, isbn: 1138676616,
This book examines the development of English as a written vernacular and identifies that development as a process of community building that occurred in a multilingual context. Moving through the eighth century to the thirteenth century, and finally to the sixteenth-century antiquarians who collected medieval manuscripts, it suggests that this important period in the history of English can only be understood if we loosen our insistence on a sharp divide between Old and Middle English and place
J.R.R. Tolkien's Double Worlds and Creative Process: Language and Life
By Palgrave Macmillan
A close colleague of J.R.R. Tolkien for many years during their editorial work on the various manuscripts of the Ancrene Wisse at Oxford University, Arne Zettersten offers here a personally-informed analysis of Tolkien's strongly visual fantasy fiction. In light of Tolkien's unusual life experience and enthusiasm for the study of languages, Zettersten locates the same animating passions in the well-known fictions that drove that great author as a youth, a soldier, a linguist, and an Oxford


text:
Lathrostizus shenyangensis är en stekelart som beskrevs av Xu och Mao-Ling Sheng 1994. Lathrostizus shenyangensis ingår i släktet Lathrostizus och familjen brokparasitsteklar. Inga underarter finns listade i Catalogue of Life.

Källor

Brokparasitsteklar
shenyangensis


text:
Review: Yuneec Typhoon Q500 4K Drone
camera | drone | quadcopter | August 1, 2015
It's rare that I get my hands on a gadget these days that lives up to my expectations, let alone exceeds them, but Yuneec did both with their incredible Typhoon Q500 4K drone. This is no toy quadcopter. This is a serious piece of aerial filmmaking equipment, and it does a spectacular job doing what it's made for.
The Q500 4K is designed to be both easy to use and incredibly powerful, packing in technologies to help make flying safe and simple for beginner drone pilots, and also provides advanced controls for those who prefer to have full control over even the smallest movements.
When purchased in its premium kit for $1449, you get a complete package that not only includes the drone, its touchscreen remote, and its accessories, but two battery packs, a heavy-duty aluminum travel case and an accessory that lets you use its 4K camera and gimbal as a sort of portable Steadicam – basically giving you two pieces of pro video gear for the price of one.
Using the drone is as simple as screwing on its four propellers (the "A" props tighten one direction, and the "B" props tighten the other), placing an MicroSD card in the camera slot, sliding the battery pack in, and then turning on the controller and the drone itself. Once on, the touchscreen remote automatically finds and pairs with the drone, and displays useful messages to confirm connectivity.
Stand back at least 26 feet away, press the Start/Stop button on the remote, and the propellers start spinning. In the default "Smart" mode, pressing forward on the left stick lifts the drone, and pulling back lowers it. Letting go makes the drone hover at the current height. Pushing left or right on the left stick rotates the drone in position, while the right stick acts moves it forward, backwards, left or right from your current position. In addition, Smart mode has two sub-modes: Follow Me and Watch Me. Follow Me makes the drone fly wherever you walk, and Watch Me aims the camera at the holder of the remote and stays fixed on them as they move. It's ridiculously simple and intuitive.
In addition to showing exactly what the drone's camera is seeing, the remote also includes controls for adjusting the tilt of the camera, as well as the speed at which the flight controls operate. I recommend starting off in slow (turtle) mode, and gradually ramping up to fast (rabbit) mode as you get more comfortable. The controller also has a mode called "Angle" which works more like a traditional R/C flyer, where your moves are relative to the position of the drone itself. This is much more difficult to use, and really best left to pro flyers and show-offs. I can see no good reason to use this mode for most people. The last mode is called "home" – which I like to call "oh crap" mode. This automatically returns the drone to whoever is holding the controller (about 13 to 26 feet away from them), and lands it safely (assuming the area is clear of obstacles.) This panic button comes in handy if you lose the drone in the bright sun or just want to bring it home from a long distance. Speaking of bright sun, I wish the screen on the remote were a bit easier to see outdoors. There is a snap-on screen shade that helps a bit, but it's less than an ideal solution.
The camera in the Yuneec captures sharp 4K (3840×2160) resolution video at 24, 25 or 30fps, or 4096×2160 at 24 or 25 fps, and also can do 1080p at 60 or even 120fps for 2x slow motion video, among other frame rates. Overall, the video quality is very good – on par with my GoPro Hero 4 Black, though not as film-like as a high-end pro camera like a RED One or a Canon XC10. Still, it's more than sufficient for most applications, and is clear, smooth and easy to watch. While you can pan and tilt the camera, there's no zoom feature. The on-board gimbal does a great job keeping shots smooth in flight.
Check out some of my sample footage below (note that any compression artifacts are due to YouTube compression, and not there in the source video). Be sure to switch to 4K playback if your computer supports it.
A few specs worth mentioning are flying time and range for the drone. Air time is approximately 25 minutes per battery pack, so if you plan on shooting longer than that, definitely keep a spare charged up. Fortunately, the system is smart enough to warn you and land if the battery gets too low. Maximum operating range is about 1,500 feet, but video and images can't be reliably captured more than about 1,200 to 1,400 feet from the operator. In addition, there's geofence capability which can ensure that the drone never goes more than 300 feet away from the operator. Top speed for the drone is 15 mph when GPS lock is engaged (which you want on.)
You can also use the drone's camera to shoot 12 megapixel still images (JPG or RAW) with the camera, but in automatic exposure mode, I found them to be a little on the dim side, so they need some post-production tuning. The images below were shot on a bright, sunny day using the default settings. Click the sample images below for full-resolution:
But between its flying capabilities, very good 4K video, and rich accessory package, the still image quality shortfall is a minor one, and certainly not a deal killer.
If the Yuneec were to simply package the drone and camera in its box for under $1500, that would be worth the money, but they throw in another awesome accessory, the CGO Steadygrip. By sliding the 4K camera and its gimbal off its drone mount and onto the Steadygrip, you get a stabilized 4K video rig for handheld shooting too. A comparable handheld setup with a GoPro 4K camera and a gyroscopic gimbal would run you around $700 to $800.
The Steadygrip is a serious bonus. It runs on eight AA rechargeable batteries (not included), and connects via Wi-Fi to an app on your smartphone, providing a viewfinder and camera controls using your phone as the display. Its simple, but clever clip can hold a wide variety of phones. Here's some sample footage I shot using the Steadygrip:
The system comes with some great quick-start reference materials to help get you up and running quickly, and Yuneec offers excellent supplemental documentation in the form of tutorial videos, like the one below:
For anyone seriously considering aerial video work, I highly recommend the Typhoon Q500 4K drone. It's jampacked with features, and lets videographers focus on their shots rather than the complexity of flying. It's easy to fly, relatively idiot-proof, and captures great 4K video. With the added bonus of the Steadygrip and the aluminum carrying case, it's a very well priced package, offering excellent value as well.
The Proto "M": A Compact Holographic Display and Media Device
Santa and Reindeer Flying Drone: Ho-Ho-Hovercraft
Dasung Paperlike 253 3K HDMI E-ink Monitor: Stock Footage
Government Developing Confetti Launching Anti-Drone Technology
DIY Wooden Security Camera Birdhouse: Big Bird Is Watching


In 2015, Big Bang made their long-awaited comeback after 3 years of hiatus and solo activities, driving their fans into delirium.
Alice in Wonderland meets Capitol fashion?
Giving up eyesight for looks.
It's more than Fantastic, Baby.
6. And not to mention innuendos.
8. With disregard to recited choreography..
15. And more to come!


text:
Q: CORS error using fetch API - React create app I'm consuming an API using fetch but i'm getting CORS error.
I tried multiples headers, but I'm not understading what's the problem.
I'm not the owner of the API, so I couldn't change it, but checking the response it's returning access-control-allow-origin.
Following is my request method:
export const execPOST = (url, body) => {
  return fetch(url, {
    method: "POST",
    headers: {
      "Access-Control-Allow-Origin": "*",
      "Content-Type": "application/json"
    },
    body: JSON.stringify(body)
  });
};

The response is:
Request URL: http://api
Request Method: OPTIONS
Status Code: 405 Method Not Allowed
Remote Address: ip
Referrer Policy: no-referrer-when-downgrade
Response Headers:
Access-Control-Allow-Origin: *

Isn't this response above enough to allow my request?
console error:

OPTIONS http://api net::ERR_ABORTED 405 (Method Not Allowed)
      Access to fetch at 'http://api' from origin 'http://localhost:3000' has been blocked by CORS policy: Response to preflight request doesn't pass access control check: It does not have HTTP ok status.

I got this working (meanwhile I develop) using "https://cors-anywhere.herokuapp.com/", but I don't think that I should use this for production enviroment.
I found a lot of material about this problem, but nothing that worked besides implements a backend to make the request or use something else as a proxy to make the request and so on...

A: Update code as given below (use 'mode' with the value 'no-cors' ):
For more details follow the link => https://developer.mozilla.org/en-US/docs/Web/API/Fetch_API/Using_Fetch
export const execPOST = (url: string, body: any) => {
  return fetch(url, {
    mode: 'no-cors',
    method: 'POST',
    headers: {
      'Content-Type': 'application/json'
    },
    body: JSON.stringify(body)
  });
};

A: CORS headers are set by the API to protect users from malicious code making requests to sites on their behalf.
This means that you cannot enable or disable it from the client side as the Access-Control-Allow-Origin header is a server side only header.
If you don't have access to the API to change the headers then you won't be able to use the API from the client side.
In production you would have to create your own API that will handle the requests to the API you are trying to contact.